메뉴 건너뛰기




Volumn 90, Issue 5, 2016, Pages 1021-1024

Highlight report: Launch of a large integrated European in vitro toxicology project: EU-ToxRisk

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL SAFETY; EDITORIAL; EUROPEAN; HUMAN; NONHUMAN; PRIORITY JOURNAL; RISK ASSESSMENT; TOXICITY TESTING; TOXICOKINETICS; TOXICOLOGY; TRANSCRIPTOMICS; ANIMAL; ANIMAL TESTING ALTERNATIVE; COOPERATION; EUROPE; IN VITRO STUDY; INTERNATIONAL COOPERATION; MEDICAL RESEARCH; ORGANIZATION AND MANAGEMENT; PROCEDURES; PROGRAM DEVELOPMENT; WORKFLOW;

EID: 84961653980     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-016-1698-7     Document Type: Editorial
Times cited : (50)

References (40)
  • 1
    • 84962861082 scopus 로고    scopus 로고
    • Toward good read-across practice (GRAP) guidance
    • PID: 26863606
    • Ball N, Cronin MT, Shen J et al (2016) Toward good read-across practice (GRAP) guidance. ALTEX. doi:10.14573/altex.1601251
    • (2016) ALTEX
    • Ball, N.1    Cronin, M.T.2    Shen, J.3
  • 3
    • 84861744139 scopus 로고    scopus 로고
    • A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing—t4 report*
    • PID: 22307314
    • Basketter DA, Clewell H, Kimber I et al (2012) A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing—t4 report*. ALTEX 29(1):3–91
    • (2012) ALTEX , vol.29 , Issue.1 , pp. 3-91
    • Basketter, D.A.1    Clewell, H.2    Kimber, I.3
  • 4
    • 84948166805 scopus 로고    scopus 로고
    • Chemical safety assessment using read-across: assessing the use of novel testing methods to strengthen the evidence base for decision making
    • PID: 25956009
    • Berggren E, Amcoff P, Benigni R et al (2015) Chemical safety assessment using read-across: assessing the use of novel testing methods to strengthen the evidence base for decision making. Environ Health Perspect 123(12):1232–1240. doi:10.1289/ehp.1409342
    • (2015) Environ Health Perspect , vol.123 , Issue.12 , pp. 1232-1240
    • Berggren, E.1    Amcoff, P.2    Benigni, R.3
  • 6
    • 84946763147 scopus 로고    scopus 로고
    • Toward a unifying strategy for the structure-based prediction of toxicological endpoints
    • PID: 26553148
    • Carrio P, Sanz F, Pastor M (2015) Toward a unifying strategy for the structure-based prediction of toxicological endpoints. Arch Toxicol. doi:10.1007/s00204-015-1618-2
    • (2015) Arch Toxicol
    • Carrio, P.1    Sanz, F.2    Pastor, M.3
  • 7
    • 84940727150 scopus 로고    scopus 로고
    • SEURAT: Safety evaluation ultimately replacing animal testing—recommendations for future research in the field of predictive toxicology
    • COI: 1:CAS:528:DC%2BC2cXitVSitb%2FN, PID: 25433540
    • Daston G, Knight DJ, Schwarz M et al (2015) SEURAT: Safety evaluation ultimately replacing animal testing—recommendations for future research in the field of predictive toxicology. Arch Toxicol 89(1):15–23. doi:10.1007/s00204-014-1421-5
    • (2015) Arch Toxicol , vol.89 , Issue.1 , pp. 15-23
    • Daston, G.1    Knight, D.J.2    Schwarz, M.3
  • 8
    • 84963677203 scopus 로고    scopus 로고
    • EU: EU-ToxRisk to start in 2016
    • EU-ToxRisk (2015) EU: EU-ToxRisk to start in 2016. ALTEX 32(4):403–404
    • (2015) ALTEX , vol.32 , Issue.4 , pp. 403-404
    • EU-ToxRisk1
  • 10
    • 84921416823 scopus 로고    scopus 로고
    • The SEURAT-1 approach towards animal free human safety assessment
    • PID: 25372315
    • Gocht T, Berggren E, Ahr HJ et al (2015) The SEURAT-1 approach towards animal free human safety assessment. ALTEX 32(1):9–24. doi:10.14573/altex.1408041
    • (2015) ALTEX , vol.32 , Issue.1 , pp. 9-24
    • Gocht, T.1    Berggren, E.2    Ahr, H.J.3
  • 11
    • 84883464564 scopus 로고    scopus 로고
    • Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
    • COI: 1:CAS:528:DC%2BC3sXhtlahtr3N, PID: 23974980
    • Godoy P, Hewitt NJ, Albrecht U et al (2013) Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Arch Toxicol 87(8):1315–1530. doi:10.1007/s00204-13-1078-5
    • (2013) Arch Toxicol , vol.87 , Issue.8 , pp. 1315-1530
    • Godoy, P.1    Hewitt, N.J.2    Albrecht, U.3
  • 13
    • 84856967407 scopus 로고    scopus 로고
    • Highlight report: towards the replacement of in vivo repeated dose systemic toxicity testing
    • COI: 1:CAS:528:DC%2BC3MXhs1GhtbnF, PID: 22187068
    • Hengstler JG, Marchan R, Leist M (2012) Highlight report: towards the replacement of in vivo repeated dose systemic toxicity testing. Arch Toxicol 86(1):13–15. doi:10.1007/s00204-011-0798-7
    • (2012) Arch Toxicol , vol.86 , Issue.1 , pp. 13-15
    • Hengstler, J.G.1    Marchan, R.2    Leist, M.3
  • 15
    • 84872305587 scopus 로고    scopus 로고
    • Stress response pathways, toxicity pathways and adverse outcome pathways
    • COI: 1:CAS:528:DC%2BC38Xhs1Kjt7zM, PID: 23149676
    • Jennings P (2013) Stress response pathways, toxicity pathways and adverse outcome pathways. Arch Toxicol 87(1):13–14. doi:10.1007/s00204-012-0974-4.76
    • (2013) Arch Toxicol , vol.87 , Issue.1 , pp. 13-14
    • Jennings, P.1
  • 16
    • 84872335543 scopus 로고    scopus 로고
    • An overview of transcriptional regulation in response to toxicological insult
    • COI: 1:CAS:528:DC%2BC38Xht1Grt7vN, PID: 22926699
    • Jennings P, Limonciel A, Felice L, Leonard MO (2013) An overview of transcriptional regulation in response to toxicological insult. Arch Toxicol 87(1):49–72. doi:10.1007/s00204-012-0919-y
    • (2013) Arch Toxicol , vol.87 , Issue.1 , pp. 49-72
    • Jennings, P.1    Limonciel, A.2    Felice, L.3    Leonard, M.O.4
  • 20
    • 59849124092 scopus 로고    scopus 로고
    • The dawning of a new age of toxicology
    • PID: 18551234
    • Leist M, Hartung T, Nicotera P (2008) The dawning of a new age of toxicology. ALTEX 25(2):103–114
    • (2008) ALTEX , vol.25 , Issue.2 , pp. 103-114
    • Leist, M.1    Hartung, T.2    Nicotera, P.3
  • 21
    • 84904901979 scopus 로고    scopus 로고
    • Consensus report on the future of animal-free systemic toxicity testing
    • PID: 25061899
    • Leist M, Hasiwa N, Rovida C et al (2014) Consensus report on the future of animal-free systemic toxicity testing. ALTEX 31(3):341–356. doi:10.14573/altex.1406091
    • (2014) ALTEX , vol.31 , Issue.3 , pp. 341-356
    • Leist, M.1    Hasiwa, N.2    Rovida, C.3
  • 22
    • 84928125522 scopus 로고    scopus 로고
    • Predicting hepatotoxicity using ToxCast in vitro bioactivity and chemical structure
    • COI: 1:CAS:528:DC%2BC2MXjtVahtrc%3D, PID: 25697799
    • Liu J, Mansouri K, Judson RS et al (2015) Predicting hepatotoxicity using ToxCast in vitro bioactivity and chemical structure. Chem Res Toxicol 28(4):738–751. doi:10.1021/tx500501h
    • (2015) Chem Res Toxicol , vol.28 , Issue.4 , pp. 738-751
    • Liu, J.1    Mansouri, K.2    Judson, R.S.3
  • 23
    • 84942502605 scopus 로고    scopus 로고
    • Probabilistic hazard assessment for skin sensitization potency by dose-response modeling using feature elimination instead of quantitative structure-activity relationships
    • COI: 1:CAS:528:DC%2BC2MXps1Wntrk%3D, PID: 26046447
    • Luechtefeld T, Maertens A, McKim JM, Hartung T, Kleensang A, Sa-Rocha V (2015) Probabilistic hazard assessment for skin sensitization potency by dose-response modeling using feature elimination instead of quantitative structure-activity relationships. J Appl Toxicol 35(11):1361–1371. doi:10.1002/jat.3172
    • (2015) J Appl Toxicol , vol.35 , Issue.11 , pp. 1361-1371
    • Luechtefeld, T.1    Maertens, A.2    McKim, J.M.3    Hartung, T.4    Kleensang, A.5    Sa-Rocha, V.6
  • 24
    • 84943328804 scopus 로고    scopus 로고
    • Quantitative adverse outcome pathway analysis of hatching in zebrafish with CuO nanoparticles
    • COI: 1:CAS:528:DC%2BC2MXhsFWqtLzL, PID: 26378804
    • Muller EB, Lin S, Nisbet RM (2015) Quantitative adverse outcome pathway analysis of hatching in zebrafish with CuO nanoparticles. Environ Sci Technol 49(19):11817–11824. doi:10.1021/acs.est.5b01837
    • (2015) Environ Sci Technol , vol.49 , Issue.19 , pp. 11817-11824
    • Muller, E.B.1    Lin, S.2    Nisbet, R.M.3
  • 25
    • 84963708576 scopus 로고    scopus 로고
    • Toxicity testing in the 21st century: a vision and a strategy. Washington
    • NRC (2007) Toxicity testing in the 21st century: a vision and a strategy. Washington, DC
    • (2007) DC
  • 26
    • 84955382107 scopus 로고    scopus 로고
    • Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration
    • COI: 1:CAS:528:DC%2BC2MXitV2itrzE, PID: 26705709
    • Pallocca G, Grinberg M, Henry M et al (2016) Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration. Arch Toxicol 90(1):159–180. doi:10.1007/s00204-015-1658-7
    • (2016) Arch Toxicol , vol.90 , Issue.1 , pp. 159-180
    • Pallocca, G.1    Grinberg, M.2    Henry, M.3
  • 27
    • 84910681772 scopus 로고    scopus 로고
    • Read-across approaches—misconceptions, promises and challenges ahead
    • PID: 25368965
    • Patlewicz G, Ball N, Becker RA et al (2014) Read-across approaches—misconceptions, promises and challenges ahead. ALTEX 31(4):387–396. doi:10.14573/altex.1410071
    • (2014) ALTEX , vol.31 , Issue.4 , pp. 387-396
    • Patlewicz, G.1    Ball, N.2    Becker, R.A.3
  • 28
    • 84940606580 scopus 로고    scopus 로고
    • A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors
    • COI: 1:CAS:528:DC%2BC2MXhtlChu7fM, PID: 26272509
    • Rempel E, Hoelting L, Waldmann T et al (2015) A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol 89(9):1599–1618. doi:10.1007/s00204-015-1573-y
    • (2015) Arch Toxicol , vol.89 , Issue.9 , pp. 1599-1618
    • Rempel, E.1    Hoelting, L.2    Waldmann, T.3
  • 29
    • 84921415920 scopus 로고    scopus 로고
    • Integrated testing strategies (ITS) for safety assessment
    • PID: 25413849
    • Rovida C, Alepee N, Api AM et al (2015a) Integrated testing strategies (ITS) for safety assessment. ALTEX 32(1):25–40. doi:10.14573/altex.1411011
    • (2015) ALTEX , vol.32 , Issue.1 , pp. 25-40
    • Rovida, C.1    Alepee, N.2    Api, A.M.3
  • 30
    • 84938603406 scopus 로고    scopus 로고
    • Toxicity testing in the 21st century beyond environmental chemicals
    • PID: 26168280
    • Rovida C, Asakura S, Daneshian M et al (2015b) Toxicity testing in the 21st century beyond environmental chemicals. ALTEX 32(3):171–181. doi:10.14573/altex.1506201
    • (2015) ALTEX , vol.32 , Issue.3 , pp. 171-181
    • Rovida, C.1    Asakura, S.2    Daneshian, M.3
  • 34
    • 84887816244 scopus 로고    scopus 로고
    • A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment
    • PID: 24161465
    • Scholz S, Sela E, Blaha L et al (2013) A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment. Regul Toxicol Pharmacol 67(3):506–530. doi:10.1016/j.yrtph.2013.10.003
    • (2013) Regul Toxicol Pharmacol , vol.67 , Issue.3 , pp. 506-530
    • Scholz, S.1    Sela, E.2    Blaha, L.3
  • 36
    • 84922433050 scopus 로고    scopus 로고
    • Applying adverse outcome pathways (AOPs) to support integrated approaches to testing and assessment (IATA)
    • PID: 25261300
    • Tollefsen KE, Scholz S, Cronin MT et al (2014) Applying adverse outcome pathways (AOPs) to support integrated approaches to testing and assessment (IATA). Regul Toxicol Pharmacol 70(3):629–640. doi:10.1016/j.yrtph.2014.09.009
    • (2014) Regul Toxicol Pharmacol , vol.70 , Issue.3 , pp. 629-640
    • Tollefsen, K.E.1    Scholz, S.2    Cronin, M.T.3
  • 37
    • 84937827022 scopus 로고    scopus 로고
    • The ChemScreen project to design a pragmatic alternative approach to predict reproductive toxicity of chemicals
    • PID: 25656794
    • van der Burg B, Wedebye EB, Dietrich DR et al (2015) The ChemScreen project to design a pragmatic alternative approach to predict reproductive toxicity of chemicals. Reprod Toxicol 55:114–123. doi:10.1016/j.reprotox.2015.01.008
    • (2015) Reprod Toxicol , vol.55 , pp. 114-123
    • van der Burg, B.1    Wedebye, E.B.2    Dietrich, D.R.3
  • 39
    • 84896355899 scopus 로고    scopus 로고
    • Quantitative high content imaging of cellular adaptive stress response pathways in toxicity for chemical safety assessment
    • COI: 1:CAS:528:DC%2BC2cXhtVKktL8%3D, PID: 24450961
    • Wink S, Hiemstra S, Huppelschoten S, Danen E, Niemeijer M, Hendriks G, Vrieling H, Herpers B, van de Water B (2014) Quantitative high content imaging of cellular adaptive stress response pathways in toxicity for chemical safety assessment. Chem Res Toxicol 27(3):338–355. doi:10.1021/tx4004038
    • (2014) Chem Res Toxicol , vol.27 , Issue.3 , pp. 338-355
    • Wink, S.1    Hiemstra, S.2    Huppelschoten, S.3    Danen, E.4    Niemeijer, M.5    Hendriks, G.6    Vrieling, H.7    Herpers, B.8    van de Water, B.9
  • 40
    • 84962920734 scopus 로고    scopus 로고
    • Supporting read-across using biological data
    • Zhu H, Bouhifd M, Kleinstreuer N et al (2016) Supporting read-across using biological data. ALTEX. doi:10.14573/altex.1601252
    • (2016) ALTEX
    • Zhu, H.1    Bouhifd, M.2    Kleinstreuer, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.