Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytes

Brain Research

Volumn 1638, Issue , 2016, Pages 57-73

  Pei, Ying ^a   Peng, Jun ^b   Behl, Mamta ^c   Sipes, Nisha S ^c   Shockley, Keith R ^c   Rao, Mahendra S ^d   Tice, Raymond R ^c   Zeng, Xianmin ^a,b  

^a XCell Science Inc   (United States)

^b BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^d NxCell Inc   (United States)

Author keywords

Astrocytes; Drug screening; iPSC; Lineage specific reporter lines; Neural stem cells; Neurons; Neurotoxicity

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 3,3',5,5' TETRABROMOBISPHENOL; 4,4' ISOPROPYLIDENEDIPHENOL; ACRYLAMIDE; ALDICARB; BIS(TRIBUTYLTIN) OXIDE; CARBARIL; CHLORPHENOTANE; CHLORPYRIFOS; COLCHICINE; CYCLODEPSIPEPTIDE; DELTAMETHRIN; DIAZEPAM; DIELDRIN; DIETHYLSTILBESTROL; FLAME RETARDANT; FLUOROURACIL; HEPTACHLOR; HEXACHLOROPHENE; HEXANE; HYDROXYUREA; LINDANE; NEUROTOXIN; OXIDOPAMINE; PARATHION; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PROPYLTHIOURACIL; ROTENONE; TRIPHENYLPHOSPHATE; UNCLASSIFIED DRUG; VALINOMYCIN;

ARTICLE; ASTROCYTE; CELL POPULATION; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; MICROARRAY ANALYSIS; MTT ASSAY; NEURAL STEM CELL; NEUROTOXICITY; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SCREENING; TOXICITY TESTING; CELL CULTURE; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; DRUG EFFECTS; INDUCED PLURIPOTENT STEM CELL; METABOLISM; NERVE CELL; NEUROTOXICITY SYNDROMES; PRECLINICAL STUDY; PROCEDURES;

ASTROCYTES; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; DRUG EVALUATION, PRECLINICAL; HUMANS; INDUCED PLURIPOTENT STEM CELLS; NEURAL STEM CELLS; NEURONS; NEUROTOXICITY SYNDROMES;

EID: 84939857473     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2015.07.048     Document Type: Article

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