Combination of multiple neural crest migration assays to identify environmental toxicants from a proof-of-concept chemical library

Archives of Toxicology

Volumn 91, Issue 11, 2017, Pages 3613-3632

  Nyffeler, Johanna ^a,b   Dolde, Xenia ^a   Krebs, Alice ^a   Pinto Gil, Kevin ^c   Pastor, Manuel ^c   Behl, Mamta ^d   Waldmann, Tanja ^a   Leist, Marcel ^a,b  

^a UNIVERSITY OF KONSTANZ   (Germany)

^b Research Training Group RTG1331   (Germany)

^c UNIVERSITAT POMPEU FABRA   (Spain)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Cell migration; Cell tracking; Cytotoxicity; Developmental toxicity; High content imaging; Human stem cells

Indexed keywords

2,2',4,4',5,5' HEXABROMODIPHENYL ETHER; 4,4' ISOPROPYLIDENEDIPHENOL; ACENAPHTHYLENE; BERBERINE; CHLORPHENOTANE; CHLORPYRIFOS; DIBENZ[A,C]ANTHRACENE; DIELDRIN; DIETHYLSTILBESTROL; FLAME RETARDANT; HEPTACHLOR; HEXACHLOROPHENE; INDUSTRIAL CHEMICAL; ORGANOCHLORINE PESTICIDE; ORGANOPHOSPHORUS COMPOUND; OXIDOPAMINE; PESTICIDE; POLYBROMINATED DIPHENYL ETHER; POLYCYCLIC AROMATIC HYDROCARBON; TETRABROMOBISPHENOL A; TOXIC SUBSTANCE; VALINOMYCIN;

ARTICLE; CELL FUNCTION; CELL MIGRATION; CELL MIGRATION ASSAY; CELL STRUCTURE; CELL TRACKING; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ECOTOXICITY; FOLLOW UP; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; NERVE CELL DIFFERENTIATION; NEURAL CREST CELL; NEUROTOXICITY; PHYSICAL CHEMISTRY; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; CELL CULTURE; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; NEURAL CREST; PRECLINICAL STUDY; PROCEDURES; TIME LAPSE IMAGING; TOXICITY TESTING;

CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DDT; DRUG EVALUATION, PRECLINICAL; HEPTACHLOR; HUMANS; NEURAL CREST; TIME-LAPSE IMAGING; TOXICITY TESTS;

EID: 85018724518     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-017-1977-y     Document Type: Article

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