Neurobehavioural effects of developmental toxicity

The Lancet Neurology

Volumn 13, Issue 3, 2014, Pages 330-338

  Grandjean, Philippe ^a,b   Landrigan, Philip J ^c  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; BRAIN; DEVELOPMENTAL DISABILITIES; ENVIRONMENTAL EXPOSURE; HUMANS; METHYLMERCURY COMPOUNDS; NEUROTOXICITY SYNDROMES; POLYCHLORINATED BIPHENYLS;

EID: 84894029844     PISSN: 14744422     EISSN: 14744465     Source Type: Journal    
DOI: 10.1016/S1474-4422(13)70278-3     Document Type: Review

References (115)

1. Bloom B, Cohen RA, Freeman G Summary health statistics for U.S. children: National Health Interview Survey, 2009. Vital Health Stat 2010, 10:1-82.
2. Landrigan PJ, Lambertini L, Birnbaum LS A research strategy to discover the environmental causes of autism and neurodevelopmental disabilities. Environ Health Perspect 2012, 120:a258-a260.
3. Bellinger DC Interpreting epidemiologic studies of developmental neurotoxicity: conceptual and analytic issues. Neurotoxicol Teratol 2009, 31:267-274.
4. Gould E Childhood lead poisoning: conservative estimates of the social and economic benefits of lead hazard control. Environ Health Perspect 2009, 117:1162-1167.
5. Scientific frontiers in developmental toxicology and risk assessment 2000, National Research Council, National Academies Press, Washington, DC.
6. Grandjean P, Landrigan PJ Developmental neurotoxicity of industrial chemicals. Lancet 2006, 368:2167-2178.
7. Grandjean P Only one chance. How environmental pollution impairs brain development - and how to protect the brains of the next generation 2013, Oxford University Press, New York.
8. Rice D, Barone S Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Environ Health Perspect 2000, 108(suppl 3):511-533.
9. Needleman HL The removal of lead from gasoline: historical and personal reflections. Environ Res 2000, 84:20-35.
10. Grandjean P, Satoh H, Murata K, Eto K Adverse effects of methylmercury: environmental health research implications. Environ Health Perspect 2010, 118:1137-1145.
11. Landrigan PJ, Goldman LR Children's vulnerability to toxic chemicals: a challenge and opportunity to strengthen health and environmental policy. Health Aff 2011, 30:842-850.
12. Weiss B Food additives and environmental chemicals as sources of childhood behavior disorders. J Am Acad Child Psychiatry 1982, 21:144-152.
13. Needham LL, Grandjean P, Heinzow B, et al. Partition of environmental chemicals between maternal and fetal blood and tissues. Environ Sci Technol 2011, 45:1121-1126.
14. Body burden-the pollution in newborns 2005, Environmental Working Group, Environmental Working Group, Washington, DC.
15. Zheng W, Aschner M, Ghersi-Egea JF Brain barrier systems: a new frontier in metal neurotoxicological research. Toxicol Appl Pharmacol 2003, 192:1-11.
16. Bose R, Onishchenko N, Edoff K, Janson Lang AM, Ceccatelli S Inherited effects of low-dose exposure to methylmercury in neural stem cells. Toxicol Sci 2012, 130:383-390.
17. Costa LG Current issues in organophosphate toxicology. Clin Chim Acta 2006, 366:1-13.
18. Augusti-Tocco G, Biagioni S, Tata AM Acetylcholine and regulation of gene expression in developing systems. J Mol Neurosci 2006, 30:45-48.
19. Roth TL Epigenetics of neurobiology and behavior during development and adulthood. Dev Psychobiol 2012, 54:590-597.
20. Lanphear BP, Hornung R, Khoury J, et al. Low-level environmental lead exposure and children's intellectual function: an international pooled analysis. Environ Health Perspect 2005, 113:894-899.
21. Budtz-Jorgensen E, Bellinger D, Lanphear B, Grandjean P An international pooled analysis for obtaining a benchmark dose for environmental lead exposure in children. Risk Anal 2013, 33:450-461.
22. Grandjean P Even low-dose lead exposure is hazardous. Lancet 2010, 376:855-856.
23. Mazumdar M, Bellinger DC, Gregas M, Abanilla K, Bacic J, Needleman HL Low-level environmental lead exposure in childhood and adult intellectual function: a follow-up study. Environ Health 2011, 10:24.
24. Cecil KM, Brubaker CJ, Adler CM, et al. Decreased brain volume in adults with childhood lead exposure. PLoS Med 2008, 5:e112.
25. Zhang N, Baker HW, Tufts M, Raymond RE, Salihu H, Elliott MR Early childhood lead exposure and academic achievement: evidence from Detroit public schools, 2008-2010. Am J Public Health 2013, 103:e72-e77.
26. Fergusson DM, Boden JM, Horwood LJ Dentine lead levels in childhood and criminal behaviour in late adolescence and early adulthood. J Epidemiol Community Health 2008, 62:1045-1050.
27. Wright JP, Dietrich KN, Ris MD, et al. Association of prenatal and childhood blood lead concentrations with criminal arrests in early adulthood. PLoS Med 2008, 5:e101.
28. Oken E, Bellinger DC Fish consumption, methylmercury and child neurodevelopment. Curr Opin Pediatr 2008, 20:178-183.
29. Debes F, Budtz-Jorgensen E, Weihe P, White RF, Grandjean P Impact of prenatal methylmercury exposure on neurobehavioral function at age 14 years. Neurotoxicol Teratol 2006, 28:536-547.
30. Julvez J, Smith GD, Golding J, et al. Genetic predisposition to cognitive deficit at age 8 years associated with prenatal methylmercury exposure. Epidemiology 2013, 24:643-650.
31. White RF, Palumbo CL, Yurgelun-Todd DA, et al. Functional MRI approach to developmental methylmercury and polychlorinated biphenyl neurotoxicity. Neurotoxicology 2011, 32:975-980.
32. Budtz-Jorgensen E, Grandjean P, Weihe P Separation of risks and benefits of seafood intake. Environ Health Perspect 2007, 115:323-327.
33. Strain JJ, Davidson PW, Bonham MP, et al. Associations of maternal long-chain polyunsaturated fatty acids, methyl mercury, and infant development in the Seychelles Child Development Nutrition Study. Neurotoxicology 2008, 29:776-782.
34. Wasserman GA, Liu X, Parvez F, et al. Water arsenic exposure and intellectual function in 6-year-old children in Araihazar, Bangladesh. Environ Health Perspect 2007, 115:285-289.
35. Hamadani JD, Tofail F, Nermell B, et al. Critical windows of exposure for arsenic-associated impairment of cognitive function in pre-school girls and boys: a population-based cohort study. Int J Epidemiol 2011, 40:1593-1604.
36. Tanaka H, Tsukuma H, Oshima A Long-term prospective study of 6104 survivors of arsenic poisoning during infancy due to contaminated milk powder in 1955. J Epidemiol 2010, 20:439-445.
37. Engel SM, Wolff MS Causal inference considerations for endocrine disruptor research in children's health. Annu Rev Public Health 2013, 34:139-158.
38. Mattson SN, Crocker N, Nguyen TT Fetal alcohol spectrum disorders: neuropsychological and behavioral features. Neurospychol Rev 2011, 21:81-101.
39. Khan K, Wasserman GA, Liu X, et al. Manganese exposure from drinking water and children's academic achievement. Neurotoxicology 2012, 33:91-97.
40. Bouchard M, Laforest F, Vandelac L, Bellinger D, Mergler D Hair manganese and hyperactive behaviors: pilot study of school-age children exposed through tap water. Environ Health Perspect 2007, 115:122-127.
41. Riojas-Rodriguez H, Solis-Vivanco R, Schilmann A, et al. Intellectual function in Mexican children living in a mining area and environmentally exposed to manganese. Environ Health Perspect 2010, 118:1465-1470.
42. Lucchini RG, Guazzetti S, Zoni S, et al. Tremor, olfactory and motor changes in Italian adolescents exposed to historical ferro-manganese emission. Neurotoxicology 2012, 33:687-696.
43. Moreno JA, Yeomans EC, Streifel KM, Brattin BL, Taylor RJ, Tjalkens RB Age-dependent susceptibility to manganese-induced neurological dysfunction. Toxicol Sci 2009, 112:394-404.
44. Choi AL, Sun G, Zhang Y, Grandjean P Developmental fluoride neurotoxicity: a systematic review and meta-analysis. Environ Health Perspect 2012, 120:1362-1368.
45. Julvez J, Grandjean P Neurodevelopmental toxicity risks due to occupational exposure to industrial chemicals during pregnancy. Ind Health 2009, 47:459-468.
46. Pele F, Muckle G, Costet N, et al. Occupational solvent exposure during pregnancy and child behaviour at age 2. Occup Environ Med 2013, 70:114-119.
47. Janulewicz PA, White RF, Martin BM, et al. Adult neuropsychological performance following prenatal and early postnatal exposure to tetrachloroethylene (PCE)-contaminated drinking water. Neurotoxicol Teratol 2012, 34:350-359.
48. Kofman O, Berger A, Massarwa A, Friedman A, Jaffar AA Motor inhibition and learning impairments in school-aged children following exposure to organophosphate pesticides in infancy. Pediatr Res 2006, 60:88-92.
49. London L, Beseler C, Bouchard MF, et al. Neurobehavioral and neurodevelopmental effects of pesticide exposures. Neurotoxicology 2012, 33:887-896.
50. Torres-Sanchez L, Schnaas L, Rothenberg SJ, et al. Prenatal p,p'-DDE exposure and neurodevelopment among children 3.5-5 years of age. Environ Health Perspect 2013, 121:263-268.
51. Boucher O, Simard MN, Muckle G, et al. Exposure to an organochlorine pesticide (chlordecone) and development of 18-month-old infants. Neurotoxicology 2013, 35:162-168.
52. Rauh V, Arunajadai S, Horton M, et al. 7-year neurodevelopmental scores and prenatal exposure to chlorpyrifos, a common agricultural pesticide. Environ Health Perspect 2011, 119:1196-1201.
53. Bouchard MF, Chevrier J, Harley KG, et al. Prenatal exposure to organophosphate pesticides and IQ in 7-year old children. Environ Health Perspect 2011, 119:1189-1195.
54. Engel SM, Wetmur J, Chen J, et al. Prenatal exposure to organophosphates, paraoxonase 1, and cognitive development in childhood. Environ Health Perspect 2011, 119:1182-1188.
55. Rauh VA, Perera FP, Horton MK, et al. Brain anomalies in children exposed prenatally to a common organophosphate pesticide. Proc Natl Acad Sci USA 2012, 109:7871-7876.
56. Bjorling-Poulsen M, Andersen HR, Grandjean P Potential developmental neurotoxicity of pesticides used in Europe. Environ Health 2008, 7:50.
57. Ostrea EM, Reyes A, Villanueva-Uy E, et al. Fetal exposure to propoxur and abnormal child neurodevelopment at 2 years of age. Neurotoxicology 2012, 33:669-675.
58. Horton MK, Rundle A, Camann DE, Boyd Barr D, Rauh VA, Whyatt RM Impact of prenatal exposure to piperonyl butoxide and permethrin on 36-month neurodevelopment. Pediatrics 2011, 127:e699-e706.
59. Dingemans MM, van den Berg M, Westerink RH Neurotoxicity of brominated flame retardants: (in)direct effects of parent and hydroxylated polybrominated diphenyl ethers on the (developing) nervous system. Environ Health Perspect 2011, 119:900-907.
60. Roze E, Meijer L, Bakker A, Van Braeckel KN, Sauer PJ, Bos AF Prenatal exposure to organohalogens, including brominated flame retardants, influences motor, cognitive, and behavioral performance at school age. Environ Health Perspect 2009, 117:1953-1958.
61. Herbstman JB, Sjodin A, Kurzon M, et al. Prenatal exposure to PBDEs and neurodevelopment. Environ Health Perspect 2010, 118:712-719.
62. Eskenazi B, Chevrier J, Rauch SA, et al. In utero and childhood polybrominated diphenyl ether (PBDE) exposures and neurodevelopment in the CHAMACOS study. Environ Health Perspect 2013, 121:257-262.
63. Grandjean P, Budtz-Jorgensen E An ignored risk factor in toxicology: the total imprecision of exposure assessment. Pure Appl Chem 2010, 82:383-391.
64. Vandenberg LN, Colborn T, Hayes TB, et al. Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev 2012, 33:378-455.
65. Engel SM, Miodovnik A, Canfield RL, et al. Prenatal phthalate exposure is associated with childhood behavior and executive functioning. Environ Health Perspect 2010, 118:565-571.
66. Swan SH, Liu F, Hines M, et al. Prenatal phthalate exposure and reduced masculine play in boys. Int J Androl 2010, 33:259-269.
67. Braun JM, Kalkbrenner AE, Calafat AM, et al. Impact of early-life bisphenol A exposure on behavior and executive function in children. Pediatrics 2011, 128:873-882.
68. Perera FP, Li Z, Whyatt R, et al. Prenatal airborne polycyclic aromatic hydrocarbon exposure and child IQ at age 5 years. Pediatrics 2009, 124:e195-e202.
69. Calderon-Garciduenas L, Mora-Tiscareno A, Ontiveros E, et al. Air pollution, cognitive deficits and brain abnormalities: a pilot study with children and dogs. Brain Cogn 2008, 68:117-127.
70. Dix-Cooper L, Eskenazi B, Romero C, Balmes J, Smith KR Neurodevelopmental performance among school age children in rural Guatemala is associated with prenatal and postnatal exposure to carbon monoxide, a marker for exposure to woodsmoke. Neurotoxicology 2012, 33:246-254.
71. Vrijheid M, Martinez D, Aguilera I, et al. Indoor air pollution from gas cooking and infant neurodevelopment. Epidemiology 2012, 23:23-32.
72. Hernandez-Martinez C, Arija Val V, Escribano Subias J, Canals Sans J A longitudinal study on the effects of maternal smoking and secondhand smoke exposure during pregnancy on neonatal neurobehavior. Early Hum Dev 2012, 88:403-408.
73. Mariussen E Neurotoxic effects of perfluoroalkylated compounds: mechanisms of action and environmental relevance. Arch Toxicol 2012, 86:1349-1367.
74. Gump BB, Wu Q, Dumas AK, Kannan K Perfluorochemical (PFC) exposure in children: associations with impaired response inhibition. Environ Sci Technol 2011, 45:8151-8159.
75. Froehlich TE, Anixt JS, Loe IM, Chirdkiatgumchai V, Kuan L, Gilman RC Update on environmental risk factors for attention-deficit/hyperactivity disorder. Curr Psychiatry Rep 2011, 13:333-344.
76. Carpenter DO, Nevin R Environmental causes of violence. Physiol Behav 2010, 99:260-268.
77. Miodovnik A, Engel SM, Zhu C, et al. Endocrine disruptors and childhood social impairment. Neurotoxicology 2011, 32:261-267.
78. Volk HE, Lurmann F, Penfold B, Hertz-Picciotto I, McConnell R Traffic-related air pollution, particulate matter, and autism. JAMA Psychiatry 2013, 70:71-77.
79. Bandeen-Roche K, Glass TA, Bolla KI, Todd AC, Schwartz BS Cumulative lead dose and cognitive function in older adults. Epidemiology 2009, 20:831-839.
80. Lock EA, Zhang J, Checkoway H Solvents and Parkinson disease: a systematic review of toxicological and epidemiological evidence. Toxicol Appl Pharmacol 2013, 266:345-355.
81. Landrigan PJ, Sonawane B, Butler RN, Trasande L, Callan R, Droller D Early environmental origins of neurodegenerative disease in later life. Environ Health Perspect 2005, 113:1230-1233.
82. Lauterbach M, Solak E, Kaes J, Wiechelt J, Von Mach MA, Weilemann LS Epidemiology of hydrogen phosphide exposures in humans reported to the poison center in Mainz, Germany, 1983-2003. Clin Toxicol 2005, 43:575-581.
83. Demarest C, Torgovnick J, Sethi NK, Arsura E, Sethi PK Acute reversible neurotoxicity associated with inhalation of ethyl chloride: a case report. Clin Neurol Neurosurg 2011, 113:909-910.
84. Imamura T, Yanagawa Y, Nishikawa K, Matsumoto N, Sakamoto T Two cases of acute poisoning with acetamiprid in humans. Clin Toxicol 2010, 48:851-853.
85. Veale DJ, Wium CA, Muller GJ Amitraz poisoning in South Africa: a two year survey (2008-2009). Clin Toxicol 2011, 49:40-44.
86. Sung YF, Huang CT, Fan CK, Lin CH, Lin SP Avermectin intoxication with coma, myoclonus, and polyneuropathy. Clin Toxicol 2009, 47:686-688.
87. Yang CC Acute human toxicity of macrocyclic lactones. Curr Pharm Biotechnol 2012, 13:999-1003.
88. Lee SJ, Mulay P, Diebolt-Brown B, et al. Acute illnesses associated with exposure to fipronil-surveillance data from 11 states in the United States, 2001-2007. Clin Toxicol 2010, 48:737-744.
89. Malhotra RC, Ghia DK, Cordato DJ, Beran RG Glyphosate-surfactant herbicide-induced reversible encephalopathy. J Clin Neurosci 2010, 17:1472-1473.
90. David D, Prabhakar A, Peter JV, Pichamuthu K Human poisoning with hexastar: a hexaconazole-containing agrochemical fungicide. Clin Toxicol 2008, 46:692-693.
91. Shadnia S, Moghaddam HH Fatal intoxication with imidacloprid insecticide. Am J Emerg Med 2008, 26:634.e1-634.e4.
92. Deng X, Li G, Mei R, Sun S Long term effects of tetramine poisoning: an observational study. Clin Toxicol 2012, 50:172-175.
93. Khalil M, Abudiab M, Ahmed AE Clinical evaluation of 1,3-butadiene neurotoxicity in humans. Toxicol Ind Health 2007, 23:141-146.
94. Bellinger DC A strategy for comparing the contributions of environmental chemicals and other risk factors to neurodevelopment of children. Environ Health Perspect 2012, 120:501-507.
95. Grandjean P, Pichery C, Bellanger M, Budtz-Jorgensen E Calculation of mercury's effects on neurodevelopment. Environ Health Perspect 2012, 120:A452.
96. Bellanger M, Pichery C, Aerts D, et al. Economic benefits of methylmercury exposure control in Europe: monetary value of neurotoxicity prevention. Environ Health 2013, 12:3.
97. Trasande L, Liu Y Reducing the staggering costs of environmental disease in children, estimated at $76.6 billion in 2008. Health Aff 2011, 30:863-870.
98. Pichery C, Bellanger M, Zmirou-Navier D, Glorennec P, Hartemann P, Grandjean P Childhood lead exposure in France: benefit estimation and partial cost-benefit analysis of lead hazard control. Environ Health 2011, 10:44.
99. Lynn R, Vanhanen T IQ and the wealth of nations 2002, Praeger, Westport.
100. The world's worst pollution problems: assessing health risks at hazardous waste sites 2012, Blacksmith Institute, Blacksmith Institute, New York.
101. Trasande L, Massey RI, DiGangi J, Geiser K, Olanipekun AI, Gallagher L How developing nations can protect children from hazardous chemical exposures while sustaining economic growth. Health Aff 2011, 30:2400-2409.
102. Nevin R Understanding international crime trends: the legacy of preschool lead exposure. Environ Res 2007, 104:315-336.
103. Schwartz J Societal benefits of reducing lead exposure. Environ Res 1994, 66:105-124.
104. Toxicity testing in the 21st century: a vision and a strategy 2007, National Research Council, National Academies Press, Washington, DC.
105. Makris SL, Raffaele K, Allen S, et al. A retrospective performance assessment of the developmental neurotoxicity study in support of OECD test guideline 426. Environ Health Perspect 2009, 117:17-25.
106. Rovida C, Longo F, Rabbit RR How are reproductive toxicity and developmental toxicity addressed in REACH dossiers?. Altex 2011, 28:273-294.
107. Collins FS, Gray GM, Bucher JR Toxicology. Transforming environmental health protection. Science 2008, 319:906-907.
108. Crofton KM, Mundy WR, Lein PJ, et al. Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals. Altex 2011, 28:9-15.
109. Audouze K, Grandjean P Application of computational systems biology to explore environmental toxicity hazards. Environ Health Perspect 2011, 119:1754-1759.
110. Willighagen EL, Jeliazkova N, Hardy B, Grafstrom RC, Spjuth O Computational toxicology using the OpenTox application programming interface and Bioclipse. BMC Res Notes 2011, 4:487.
111. Science and decisions: advancing risk assessment 2009, National Research Council, National Academies Press, Washington, DC.
112. Late lessons from early warnings: science precaution, innovation. 2013, European Environment Agency, Copenhagen.
113. Moodie R, Stuckler D, Monteiro C, et al. Profits and pandemics: prevention of harmful effects of tobacco, alcohol, and ultra-processed food and drink industries. Lancet 2013, 381:670-679.
114. Grandjean P Seven deadly sins of environmental epidemiology and the virtues of precaution. Epidemiology 2008, 19:158-162.
115. Grandjean P, Eriksen ML, Ellegaard O, Wallin JA The Matthew effect in environmental science publication: a bibliometric analysis of chemical substances in journal articles. Environ Health 2011, 10:96.