Stem cell-derived immature human dorsal root ganglia neurons to identify peripheral neurotoxicants

Stem Cells Translational Medicine

Volumn 5, Issue 4, 2016, Pages 476-487

  Hoelting, Lisa ^a,b   Klima, Stefanie ^a   Karreman, Christiaan ^a   Grinberg, Marianna ^c   Meisig, Johannes ^d,e   Henry, Margit ^f   Rotshteyn, Tamara ^f   Rahnenführer, Jörg ^c   Blüthgen, Nils ^d,e   Sachinidis, Agapios ^f   Waldmann, Tanja ^a   Leist, Marcel ^a  

^a Doerenkamp Zbinden Lab for In Vitro Toxicology and Biomedicine   (Germany)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c TU DORTMUND UNIVERSITY   (Germany)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e HUMBOLDT UNIVERSITY   (Germany)

^f UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Human pluripotent stem cells; In vitro drug and toxicity testing; Neural differentiation; Peripheral neuropathies

Indexed keywords

ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; MICROARRAY ANALYSIS; NERVE FIBER GROWTH; NEUROTOXICITY; PLURIPOTENT STEM CELL; POLYMERASE CHAIN REACTION; SPINAL GANGLION; TOXICITY TESTING; TRANSCRIPTOMICS; UPREGULATION; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEURITE; PERIPHERAL NERVE; PHYSIOLOGY; POLLUTANT; PROCEDURES; TOXICITY;

POLLUTANT; ROTENONE;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; ENVIRONMENTAL POLLUTANTS; GANGLIA, SPINAL; HUMANS; MICE; NEURAL STEM CELLS; NEURITES; NEUROGENESIS; NEURONS; PERIPHERAL NERVES; PLURIPOTENT STEM CELLS; ROTENONE; TOXICITY TESTS;

EID: 84961258170     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2015-0108     Document Type: Article

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