PCB 136 atropselectively alters morphometric and functional parameters of neuronal connectivity in cultured rat hippocampal neurons via ryanodine receptor-dependent mechanisms

Toxicological Sciences

Volumn 138, Issue 2, 2014, Pages 379-392

  Yang, Dongren ^a   Kania Korwel, Izabela ^b   Ghogha, Atefeh ^a   Chen, Hao ^a   Stamou, Marianna ^a   Bose, Diptiman D ^a   Pessah, Isaac N ^a   Lehmler, Hans Joachim ^b   Lein, Pamela J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Atropselectivity; Chirality; Dendritic growth; Developmental neurotoxicity; Neuronal connectivity; Polychlorinated biphenyls; Ryanodine receptor

Indexed keywords

CALCIUM ION; POLYCHLORINATED BIPHENYL; POLYCHLORINATED BIPHENYL 136; RYANODINE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DENDRITE; HIPPOCAMPAL NEURONAL CULTURE; MORPHOMETRICS; NERVE CELL NETWORK; NONHUMAN; OSCILLATION; RAT;

ATROPSELECTIVITY; CHIRALITY; DENDRITIC GROWTH; DEVELOPMENTAL NEUROTOXICITY; NEURONAL CONNECTIVITY; POLYCHLORINATED BIPHENYLS; RYANODINE RECEPTOR;

ANIMALS; ANIMALS, NEWBORN; CALCIUM SIGNALING; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; GROWTH CONES; HIPPOCAMPUS; MICROELECTRODES; NEURONS; POLYCHLORINATED BIPHENYLS; PRIMARY CELL CULTURE; RATS; RATS, SPRAGUE-DAWLEY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; STEREOISOMERISM; SYNAPTIC TRANSMISSION;

EID: 84894262438     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft334     Document Type: Article

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