-
1
-
-
77951107086
-
Synthetic biology: Applications come of age
-
Khalil, A. S. & Collins, J. J. Synthetic biology: Applications come of age. Nat. Rev. Genet. 11, 367-379 (2010).
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 367-379
-
-
Khalil, A.S.1
Collins, J.J.2
-
2
-
-
84861440312
-
Systems metabolic engineering of microorganisms for natural and non-natural chemicals
-
Lee, J. W. et al. Systems metabolic engineering of microorganisms for natural and non-natural chemicals. Nat. Chem. Biol. 8, 536-546 (2012).
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 536-546
-
-
Lee, J.W.1
-
3
-
-
84899079198
-
A brief history of synthetic biology
-
Cameron, D. E., Bashor, C. J. & Collins, J. J. A brief history of synthetic biology. Nat. Rev. Microbiol. 12, 381-390 (2014).
-
(2014)
Nat. Rev. Microbiol.
, vol.12
, pp. 381-390
-
-
Cameron, D.E.1
Bashor, C.J.2
Collins, J.J.3
-
4
-
-
0016772949
-
Summary statement of the Asilomar conference on recombinant DNA molecules
-
Berg, P., Baltimore, D., Brenner, S., Roblin, R. O. & Singer, M. F. Summary statement of the Asilomar conference on recombinant DNA molecules. Proc. Natl Acad. Sci. USA 72, 1981-1984 (1975).
-
(1975)
Proc. Natl Acad. Sci. USA
, vol.72
, pp. 1981-1984
-
-
Berg, P.1
Baltimore, D.2
Brenner, S.3
Roblin, R.O.4
Singer, M.F.5
-
5
-
-
0016746898
-
Asilomar conference on recombinant DNA molecules
-
Berg, P., Baltimore, D., Brenner, S., Roblin, R. O. III & Singer, M. F. Asilomar conference on recombinant DNA molecules. Science 188, 991-994 (1975).
-
(1975)
Science
, vol.188
, pp. 991-994
-
-
Berg, P.1
Baltimore, D.2
Brenner, S.3
Roblin, R.O.4
Singer, M.F.5
-
6
-
-
0027794688
-
NIH guidelines for research involving recombinant DNA molecules
-
Wilson, D. J. NIH guidelines for research involving recombinant DNA molecules. Account. Res. 3, 177-185 (1993).
-
(1993)
Account. Res.
, vol.3
, pp. 177-185
-
-
Wilson, D.J.1
-
7
-
-
0035834111
-
Impact of Bt corn pollen on monarch butterfly populations: A risk assessment
-
Sears, M. K. et al. Impact of Bt corn pollen on monarch butterfly populations: A risk assessment. Proc. Natl Acad. Sci. USA 98, 11937-11942 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 11937-11942
-
-
Sears, M.K.1
-
8
-
-
0035834099
-
Assessing the impact of Cry1Ab-expressing corn pollen on monarch butterfly larvae in field studies
-
Stanley-Horn, D. E. et al. Assessing the impact of Cry1Ab-expressing corn pollen on monarch butterfly larvae in field studies. Proc. Natl Acad. Sci. USA 98, 11931-11936 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 11931-11936
-
-
Stanley-Horn, D.E.1
-
9
-
-
0036267314
-
Transgenic crops why gene flow matters
-
Snow, A. A. Transgenic crops why gene flow matters. Nat. Biotechnol. 20, 542 (2002).
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 542
-
-
Snow, A.A.1
-
10
-
-
0142123052
-
The ecological risks of transgenic plants
-
Giovannetti, M. The ecological risks of transgenic plants. Riv. Biol. 96, 207-223 (2003).
-
(2003)
Riv. Biol.
, vol.96
, pp. 207-223
-
-
Giovannetti, M.1
-
11
-
-
34047119348
-
Genetic use restriction technologies (GURTs): Strategies to impede transgene movement
-
Hills, M. J., Hall, L., Arnison, P. G. & Good, A. G. Genetic use restriction technologies (GURTs): Strategies to impede transgene movement. Trends Plant Sci. 12, 177-183 (2007).
-
(2007)
Trends Plant Sci.
, vol.12
, pp. 177-183
-
-
Hills, M.J.1
Hall, L.2
Arnison, P.G.3
Good, A.G.4
-
12
-
-
0035969540
-
Transgenic DNA introgressed into traditional maize landraces in Oaxaca, Mexico
-
Quist, D. & Chapela, I. H. Transgenic DNA introgressed into traditional maize landraces in Oaxaca, Mexico. Nature 414, 541-543 (2001).
-
(2001)
Nature
, vol.414
, pp. 541-543
-
-
Quist, D.1
Chapela, I.H.2
-
13
-
-
80052826492
-
Bacteriophages carrying antibiotic resistance genes in fecal waste from cattle, pigs, and poultry
-
Colomer-Lluch, M., Imamovic, L., Jofre, J. & Muniesa, M. Bacteriophages carrying antibiotic resistance genes in fecal waste from cattle, pigs, and poultry. Antimicrob. Agents Chemother. 55, 4908-4911 (2011).
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 4908-4911
-
-
Colomer-Lluch, M.1
Imamovic, L.2
Jofre, J.3
Muniesa, M.4
-
14
-
-
84875851718
-
Preparing synthetic biology for the world
-
Moe-Behrens, G. H., Davis, R. & Haynes, K. A. Preparing synthetic biology for the world. Front. Microbiol. 4, 5 (2013).
-
(2013)
Front. Microbiol.
, vol.4
, pp. 5
-
-
Moe-Behrens, G.H.1
Davis, R.2
Haynes, K.A.3
-
15
-
-
84857737272
-
Synthetic biology: Four steps to avoid a synthetic-biology disaster
-
Dana, G. V., Kuiken, T., Rejeski, D. & Snow, A. A. Synthetic biology: Four steps to avoid a synthetic-biology disaster. Nature 483, 29 (2012).
-
(2012)
Nature
, vol.483
, pp. 29
-
-
Dana, G.V.1
Kuiken, T.2
Rejeski, D.3
Snow, A.A.4
-
16
-
-
84879816810
-
Building-in biosafety for synthetic biology
-
Wright, O., Stan, G. B. & Ellis, T. Building-in biosafety for synthetic biology. Microbiology 159, 1221-1235 (2013).
-
(2013)
Microbiology
, vol.159
, pp. 1221-1235
-
-
Wright, O.1
Stan, G.B.2
Ellis, T.3
-
17
-
-
84957806669
-
Synthetic bugs on the loose: Containment options for deeply engineered (micro)organisms
-
Schmidt, M. & de Lorenzo, V. Synthetic bugs on the loose: Containment options for deeply engineered (micro)organisms. Curr. Opin. Biotechnol. 38, 90-96 (2016).
-
(2016)
Curr. Opin. Biotechnol.
, vol.38
, pp. 90-96
-
-
Schmidt, M.1
De Lorenzo, V.2
-
18
-
-
85013451976
-
-
(eds. McGenity, T.J., Timmis, K.N. & Nogales, B.), (Springer Berlin Heidelberg, Berlin, Heidelberg).
-
Schmidt, M. & Pei, L. in Hydrocarbon and Lipid Microbiology Protocols: Synthetic and Systems Biology - Tools (eds. McGenity, T.J., Timmis, K.N. & Nogales, B.) 185-199 (Springer Berlin Heidelberg, Berlin, Heidelberg, 2016).
-
(2016)
Hydrocarbon and Lipid Microbiology Protocols: Synthetic and Systems Biology - Tools
, pp. 185-199
-
-
Schmidt, M.1
Pei, L.2
-
19
-
-
0006878245
-
-
US Patent, 5, 723, 765
-
Oliver, M. J., Quisenberry, J. E., Trolinder, N. L. G. & Keim, D. H. Control of plant gene expression. US Patent 5, 723, 765 (1998).
-
(1998)
Control of Plant Gene Expression
-
-
Oliver, M.J.1
Quisenberry, J.E.2
Trolinder, N.L.G.3
Keim, D.H.4
-
20
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini, L. et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 263-267 (1996).
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
-
21
-
-
0031710033
-
A third-generation lentivirus vector with a conditional packaging system
-
Dull, T. et al. A third-generation lentivirus vector with a conditional packaging system. J. Virol. 72, 8463-8471 (1998).
-
(1998)
J. Virol.
, vol.72
, pp. 8463-8471
-
-
Dull, T.1
-
22
-
-
0027228422
-
Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: Concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells
-
Burns, J. C., Friedmann, T., Driever, W., Burrascano, M. & Yee, J. K. Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: Concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. Proc. Natl Acad. Sci. USA 90, 8033-8037 (1993).
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 8033-8037
-
-
Burns, J.C.1
Friedmann, T.2
Driever, W.3
Burrascano, M.4
Yee, J.K.5
-
23
-
-
0037820426
-
Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10
-
Steidler, L. et al. Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10. Nat. Biotechnol. 21, 785-789 (2003).
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 785-789
-
-
Steidler, L.1
-
24
-
-
77950825733
-
Efficacy of a Lactococcus lactis Δ pyrG vaccine delivery platform expressing chromosomally integrated hly from Listeria monocytogenes
-
Bahey-El-Din, M., Casey, P. G., Griffin, B. T. & Gahan, C. G. Efficacy of a Lactococcus lactis Δ pyrG vaccine delivery platform expressing chromosomally integrated hly from Listeria monocytogenes. Bioeng. Bugs 1, 66-74 (2010).
-
(2010)
Bioeng. Bugs
, vol.1
, pp. 66-74
-
-
Bahey-El-Din, M.1
Casey, P.G.2
Griffin, B.T.3
Gahan, C.G.4
-
25
-
-
0035377246
-
Dual system to reinforce biological containment of recombinant bacteria designed for rhizoremediation
-
Ronchel, M. C. & Ramos, J. L. Dual system to reinforce biological containment of recombinant bacteria designed for rhizoremediation. Appl. Environ. Microbiol. 67, 2649-2656 (2001).
-
(2001)
Appl. Environ. Microbiol.
, vol.67
, pp. 2649-2656
-
-
Ronchel, M.C.1
Ramos, J.L.2
-
26
-
-
84885791219
-
Genomically recoded organisms expand biological functions
-
Lajoie, M. J. et al. Genomically recoded organisms expand biological functions. Science 342, 357-360 (2013).
-
(2013)
Science
, vol.342
, pp. 357-360
-
-
Lajoie, M.J.1
-
27
-
-
84922595374
-
Recoded organisms engineered to depend on synthetic amino acids
-
Rovner, A. J. et al. Recoded organisms engineered to depend on synthetic amino acids. Nature 518, 89-93 (2015).
-
(2015)
Nature
, vol.518
, pp. 89-93
-
-
Rovner, A.J.1
-
28
-
-
84923112573
-
Biocontainment of genetically modified organisms by synthetic protein design
-
Mandell, D. J. et al. Biocontainment of genetically modified organisms by synthetic protein design. Nature 518, 55-60 (2015).
-
(2015)
Nature
, vol.518
, pp. 55-60
-
-
Mandell, D.J.1
-
29
-
-
77957679279
-
Tracking, tuning, and terminating microbial physiology using synthetic riboregulators
-
Callura, J. M., Dwyer, D. J., Isaacs, F. J., Cantor, C. R. & Collins, J. J. Tracking, tuning, and terminating microbial physiology using synthetic riboregulators. Proc. Natl Acad Sci. USA 107, 15898-15903 (2010).
-
(2010)
Proc. Natl Acad Sci. USA
, vol.107
, pp. 15898-15903
-
-
Callura, J.M.1
Dwyer, D.J.2
Isaacs, F.J.3
Cantor, C.R.4
Collins, J.J.5
-
30
-
-
84922664743
-
Multilayered genetic safeguards limit growth of microorganisms to defined environments
-
Gallagher, R. R., Patel, J. R., Interiano, A. L., Rovner, A. J. & Isaacs, F. J. Multilayered genetic safeguards limit growth of microorganisms to defined environments. Nucleic Acids Res. 43, 1945-1954 (2015).
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. 1945-1954
-
-
Gallagher, R.R.1
Patel, J.R.2
Interiano, A.L.3
Rovner, A.J.4
Isaacs, F.J.5
-
31
-
-
84922678329
-
Intrinsic biocontainment: Multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes
-
Cai, Y. et al. Intrinsic biocontainment: Multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes. Proc. Natl Acad. Sci. USA 112, 1803-1808 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. 1803-1808
-
-
Cai, Y.1
-
32
-
-
85013304603
-
Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae
-
Agmon, N. et al. Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA 114, E1470-E1479 (2017).
-
(2017)
Proc. Natl Acad. Sci. USA
, vol.114
, pp. E1470-E1479
-
-
Agmon, N.1
-
33
-
-
84959323351
-
Coupling spatial segregation with synthetic circuits to control bacterial survival
-
Huang, S. et al. Coupling spatial segregation with synthetic circuits to control bacterial survival. Mol. Syst. Biol. 12, 859 (2016).
-
(2016)
Mol. Syst. Biol.
, vol.12
, pp. 859
-
-
Huang, S.1
-
34
-
-
84955192252
-
'Deadman' and 'Passcode' microbial kill switches for bacterial containment
-
Chan, C. T., Lee, J. W., Cameron, D. E., Bashor, C. J. & Collins, J. J. 'Deadman' and 'Passcode' microbial kill switches for bacterial containment. Nat. Chem. Biol. 12, 82-86 (2016).
-
(2016)
Nat. Chem. Biol.
, vol.12
, pp. 82-86
-
-
Chan, C.T.1
Lee, J.W.2
Cameron, D.E.3
Bashor, C.J.4
Collins, J.J.5
-
35
-
-
0031778132
-
Construction of an efficient biologically contained pseudomonas putida strain and its survival in outdoor assays
-
Molina, L., Ramos, C., Ronchel, M. C., Molin, S. & Ramos, J. L. Construction of an efficient biologically contained pseudomonas putida strain and its survival in outdoor assays. Appl. Environ. Microbiol. 64, 2072-2078 (1998).
-
(1998)
Appl. Environ. Microbiol.
, vol.64
, pp. 2072-2078
-
-
Molina, L.1
Ramos, C.2
Ronchel, M.C.3
Molin, S.4
Ramos, J.L.5
-
36
-
-
0025754177
-
Conditional-suicide containment system for bacteria which mineralize aromatics
-
Contreras, A., Molin, S. & Ramos, J. L. Conditional-suicide containment system for bacteria which mineralize aromatics. Appl. Environ. Microbiol. 57, 1504-1508 (1991).
-
(1991)
Appl. Environ. Microbiol.
, vol.57
, pp. 1504-1508
-
-
Contreras, A.1
Molin, S.2
Ramos, J.L.3
-
37
-
-
84875174921
-
The par toxin-antitoxin system from Enterococcus faecalis plasmid pAD1 and its chromosomal homologs
-
Weaver, K. E. The par toxin-antitoxin system from Enterococcus faecalis plasmid pAD1 and its chromosomal homologs. RNA Biol. 9, 1498-1503 (2012).
-
(2012)
RNA Biol.
, vol.9
, pp. 1498-1503
-
-
Weaver, K.E.1
-
38
-
-
84874197735
-
Type i toxin-antitoxin systems in Bacillus subtilis
-
Durand, S., Jahn, N., Condon, C. & Brantl, S. Type I toxin-antitoxin systems in Bacillus subtilis. RNA Biol. 9, 1491-1497 (2012).
-
(2012)
RNA Biol.
, vol.9
, pp. 1491-1497
-
-
Durand, S.1
Jahn, N.2
Condon, C.3
Brantl, S.4
-
39
-
-
77954694584
-
ParD toxin-antitoxin system of plasmid R1-basic contributions, biotechnological applications and relationships with closely-related toxin-antitoxin systems
-
Diago-Navarro, E. et al. parD toxin-antitoxin system of plasmid R1-basic contributions, biotechnological applications and relationships with closely-related toxin-antitoxin systems. FEBS J. 277, 3097-3117 (2010).
-
(2010)
FEBS J.
, vol.277
, pp. 3097-3117
-
-
Diago-Navarro, E.1
-
40
-
-
31344472169
-
Anatomy of the replication origin of plasmid ColE2-P9
-
Yagura, M., Nishio, S. Y., Kurozumi, H., Wang, C. F. & Itoh, T. Anatomy of the replication origin of plasmid ColE2-P9. J. Bacteriol. 188, 999-1010 (2006).
-
(2006)
J. Bacteriol.
, vol.188
, pp. 999-1010
-
-
Yagura, M.1
Nishio, S.Y.2
Kurozumi, H.3
Wang, C.F.4
Itoh, T.5
-
41
-
-
0031811125
-
Replication and control of circular bacterial plasmids
-
del Solar, G., Giraldo, R., Ruiz-Echevarría, M. J., Espinosa, M. & Díaz-Orejas, R. Replication and control of circular bacterial plasmids. Microbiol. Mol. Biol. Rev. 62, 434-464 (1998).
-
(1998)
Microbiol. Mol. Biol. Rev.
, vol.62
, pp. 434-464
-
-
Del Solar, G.1
Giraldo, R.2
Ruiz-Echevarría, M.J.3
Espinosa, M.4
Díaz-Orejas, R.5
-
42
-
-
84930197469
-
Targeted DNA degradation using a CRISPR device stably carried in the host genome
-
Caliando, B. J. & Voigt, C. A. Targeted DNA degradation using a CRISPR device stably carried in the host genome. Nat. Commun. 6, 6989 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 6989
-
-
Caliando, B.J.1
Voigt, C.A.2
-
43
-
-
85044871024
-
Precise Cas9 targeting enables genomic mutation prevention
-
Chavez, A. et al. Precise Cas9 targeting enables genomic mutation prevention. Proc. Natl Acad. Sci. USA https://doi.org/10.1073/pnas.1718148115 (2018).
-
(2018)
Proc. Natl Acad. Sci. USA
-
-
Chavez, A.1
-
44
-
-
84962460150
-
'Minimal' cell raises stakes in race to harness synthetic life
-
Callaway, E. 'Minimal' cell raises stakes in race to harness synthetic life. Nature 531, 557-558 (2016).
-
(2016)
Nature
, vol.531
, pp. 557-558
-
-
Callaway, E.1
-
45
-
-
84962855606
-
Principles for designing synthetic microbial communities
-
Johns, N. I., Blazejewski, T., Gomes, A. L. & Wang, H. H. Principles for designing synthetic microbial communities. Curr. Opin. Microbiol. 31, 146-153 (2016).
-
(2016)
Curr. Opin. Microbiol.
, vol.31
, pp. 146-153
-
-
Johns, N.I.1
Blazejewski, T.2
Gomes, A.L.3
Wang, H.H.4
-
46
-
-
84901049717
-
Syntrophic exchange in synthetic microbial communities
-
Mee, M. T., Collins, J. J., Church, G. M. & Wang, H. H. Syntrophic exchange in synthetic microbial communities. Proc. Natl Acad. Sci. USA 111, E2149-E2156 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. E2149-E2156
-
-
Mee, M.T.1
Collins, J.J.2
Church, G.M.3
Wang, H.H.4
-
47
-
-
34447342528
-
Evolved orthogonal ribosomes enhance the efficiency of synthetic genetic code expansion
-
Wang, K., Neumann, H., Peak-Chew, S. Y. & Chin, J. W. Evolved orthogonal ribosomes enhance the efficiency of synthetic genetic code expansion. Nat. Biotechnol. 25, 770-777 (2007).
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 770-777
-
-
Wang, K.1
Neumann, H.2
Peak-Chew, S.Y.3
Chin, J.W.4
-
48
-
-
77949772551
-
Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome
-
Neumann, H., Wang, K., Davis, L., Garcia-Alai, M. & Chin, J. W. Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome. Nature 464, 441-444 (2010).
-
(2010)
Nature
, vol.464
, pp. 441-444
-
-
Neumann, H.1
Wang, K.2
Davis, L.3
Garcia-Alai, M.4
Chin, J.W.5
-
49
-
-
84902856330
-
An orthogonal ribosometRNA pair via engineering of the peptidyl transferase center
-
Terasaka, N., Hayashi, G., Katoh, T. & Suga, H. An orthogonal ribosometRNA pair via engineering of the peptidyl transferase center. Nat. Chem. Biol. 10, 555-557 (2014).
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 555-557
-
-
Terasaka, N.1
Hayashi, G.2
Katoh, T.3
Suga, H.4
-
50
-
-
84937046954
-
Repurposing the translation apparatus for synthetic biology
-
Soye, B. J. D., Patel, J. R., Isaacs, F. J. & Jewett, M. C. Repurposing the translation apparatus for synthetic biology. Curr. Opin. Chem. Biol. 28, 83-90 (2015).
-
(2015)
Curr. Opin. Chem. Biol.
, vol.28
, pp. 83-90
-
-
Soye, B.J.D.1
Patel, J.R.2
Isaacs, F.J.3
Jewett, M.C.4
-
51
-
-
79960638580
-
Chemical evolution of a bacterium's genome
-
Marlière, P. et al. Chemical evolution of a bacterium's genome. Angew. Chem. Int. Edn. Engl. 50, 7109-7114 (2011).
-
(2011)
Angew. Chem. Int. Edn. Engl.
, vol.50
, pp. 7109-7114
-
-
Marlière, P.1
-
52
-
-
84860013215
-
Synthetic genetic polymers capable of heredity and evolution
-
Pinheiro, V. B. et al. Synthetic genetic polymers capable of heredity and evolution. Science 336, 341-344 (2012).
-
(2012)
Science
, vol.336
, pp. 341-344
-
-
Pinheiro, V.B.1
-
53
-
-
84900560301
-
A semi-synthetic organism with an expanded genetic alphabet
-
Malyshev, D. A. et al. A semi-synthetic organism with an expanded genetic alphabet. Nature 509, 385-388 (2014).
-
(2014)
Nature
, vol.509
, pp. 385-388
-
-
Malyshev, D.A.1
-
54
-
-
85018396526
-
Engineering genetic circuit interactions within and between synthetic minimal cells
-
Adamala, K. P., Martin-Alarcon, D. A., Guthrie-Honea, K. R. & Boyden, E. S. Engineering genetic circuit interactions within and between synthetic minimal cells. Nat. Chem. 9, 431-439 (2017).
-
(2017)
Nat. Chem.
, vol.9
, pp. 431-439
-
-
Adamala, K.P.1
Martin-Alarcon, D.A.2
Guthrie-Honea, K.R.3
Boyden, E.S.4
-
55
-
-
84909963313
-
Paper-based synthetic gene networks
-
Pardee, K. et al. Paper-based synthetic gene networks. Cell 159, 940-954 (2014).
-
(2014)
Cell
, vol.159
, pp. 940-954
-
-
Pardee, K.1
-
56
-
-
84973486576
-
Rapid, low-cost detection of Zika virus using programmable biomolecular components
-
Pardee, K. et al. Rapid, low-cost detection of Zika virus using programmable biomolecular components. Cell 165, 1255-1266 (2016).
-
(2016)
Cell
, vol.165
, pp. 1255-1266
-
-
Pardee, K.1
-
57
-
-
84988579147
-
Portable, on-demand biomolecular manufacturing
-
Pardee, K. et al. Portable, on-demand biomolecular manufacturing. Cell 167, 248-259.e12 (2016).
-
(2016)
Cell
, vol.167
, pp. 248-259e12
-
-
Pardee, K.1
-
58
-
-
84921496822
-
Cell-free metabolic engineering: Biomanufacturing beyond the cell
-
Dudley, Q. M., Karim, A. S. & Jewett, M. C. Cell-free metabolic engineering: Biomanufacturing beyond the cell. Biotechnol. J. 10, 69-82 (2015).
-
(2015)
Biotechnol. J.
, vol.10
, pp. 69-82
-
-
Dudley, Q.M.1
Karim, A.S.2
Jewett, M.C.3
-
59
-
-
84966334405
-
The All E. Coli TX-TL Toolbox 2.0: A platform for cell-free synthetic biology
-
Garamella, J., Marshall, R., Rustad, M. & Noireaux, V. The All E. coli TX-TL Toolbox 2.0: A platform for cell-free synthetic biology. ACS Synth. Biol. 5, 344-355 (2016).
-
(2016)
ACS Synth. Biol.
, vol.5
, pp. 344-355
-
-
Garamella, J.1
Marshall, R.2
Rustad, M.3
Noireaux, V.4
-
60
-
-
84896452607
-
Cell-free protein synthesis from a release factor 1 deficient Escherichia coli activates efficient and multiple site-specific nonstandard amino acid incorporation
-
Hong, S. H. et al. Cell-free protein synthesis from a release factor 1 deficient Escherichia coli activates efficient and multiple site-specific nonstandard amino acid incorporation. ACS Synth. Biol. 3, 398-409 (2014).
-
(2014)
ACS Synth. Biol.
, vol.3
, pp. 398-409
-
-
Hong, S.H.1
-
61
-
-
84860389302
-
The next generation of bacteriophage therapy
-
Lu, T. K. & Koeris, M. S. The next generation of bacteriophage therapy. Curr. Opin. Microbiol. 14, 524-531 (2011).
-
(2011)
Curr. Opin. Microbiol.
, vol.14
, pp. 524-531
-
-
Lu, T.K.1
Koeris, M.S.2
-
62
-
-
84936804003
-
Engineered phagemids for nonlytic, targeted antibacterial therapies
-
Krom, R. J., Bhargava, P., Lobritz, M. A. & Collins, J. J. Engineered phagemids for nonlytic, targeted antibacterial therapies. Nano. Lett. 15, 4808-4813 (2015).
-
(2015)
Nano. Lett.
, vol.15
, pp. 4808-4813
-
-
Krom, R.J.1
Bhargava, P.2
Lobritz, M.A.3
Collins, J.J.4
-
63
-
-
84983142945
-
Exploiting CRISPR-Cas nucleases to produce sequencespecific antimicrobials
-
Bikard, D. et al. Exploiting CRISPR-Cas nucleases to produce sequencespecific antimicrobials. Nat. Biotechnol. 32, 1146-1150 (2014).
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 1146-1150
-
-
Bikard, D.1
-
64
-
-
84983208863
-
Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases
-
Citorik, R. J., Mimee, M. & Lu, T. K. Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases. Nat. Biotechnol. 32, 1141-1145 (2014).
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 1141-1145
-
-
Citorik, R.J.1
Mimee, M.2
Lu, T.K.3
-
65
-
-
84942256417
-
Engineering modular viral scaffolds for targeted bacterial population editing
-
Ando, H., Lemire, S., Pires, D. P. & Lu, T. K. Engineering modular viral scaffolds for targeted bacterial population editing. Cell Syst. 1, 187-196 (2015).
-
(2015)
Cell Syst.
, vol.1
, pp. 187-196
-
-
Ando, H.1
Lemire, S.2
Pires, D.P.3
Lu, T.K.4
-
66
-
-
84931291929
-
Temperate and lytic bacteriophages programmed to sensitize and kill antibiotic-resistant bacteria
-
Yosef, I., Manor, M., Kiro, R. & Qimron, U. Temperate and lytic bacteriophages programmed to sensitize and kill antibiotic-resistant bacteria. Proc. Natl Acad. Sci. USA 112, 7267-7272 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. 7267-7272
-
-
Yosef, I.1
Manor, M.2
Kiro, R.3
Qimron, U.4
-
67
-
-
84958617028
-
Cheating evolution: Engineering gene drives to manipulate the fate of wild populations
-
Champer, J., Buchman, A. & Akbari, O. S. Cheating evolution: Engineering gene drives to manipulate the fate of wild populations. Nat. Rev. Genet. 17, 146-159 (2016).
-
(2016)
Nat. Rev. Genet.
, vol.17
, pp. 146-159
-
-
Champer, J.1
Buchman, A.2
Akbari, O.S.3
-
68
-
-
84949759161
-
Safeguarding CRISPR-Cas9 gene drives in yeast
-
DiCarlo, J. E., Chavez, A., Dietz, S. L., Esvelt, K. M. & Church, G. M. Safeguarding CRISPR-Cas9 gene drives in yeast. Nat. Biotechnol. 33, 1250-1255 (2015).
-
(2015)
Nat. Biotechnol.
, vol.33
, pp. 1250-1255
-
-
DiCarlo, J.E.1
Chavez, A.2
Dietz, S.L.3
Esvelt, K.M.4
Church, G.M.5
-
69
-
-
84928208828
-
Genome editing. The mutagenic chain reaction: A method for converting heterozygous to homozygous mutations
-
Gantz, V. M. & Bier, E. Genome editing. The mutagenic chain reaction: A method for converting heterozygous to homozygous mutations. Science 348, 442-444 (2015).
-
(2015)
Science
, vol.348
, pp. 442-444
-
-
Gantz, V.M.1
Bier, E.2
-
70
-
-
84949220605
-
Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi
-
Gantz, V. M. et al. Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi. Proc. Natl Acad. Sci. USA 112, E6736-E6743 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. E6736-E6743
-
-
Gantz, V.M.1
-
71
-
-
84953730637
-
A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae
-
Hammond, A. et al. A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae. Nat. Biotechnol. 34, 78-83 (2016).
-
(2016)
Nat. Biotechnol.
, vol.34
, pp. 78-83
-
-
Hammond, A.1
-
72
-
-
84925610163
-
GeneGuard: A modular plasmid system designed for biosafety
-
Wright, O., Delmans, M., Stan, G. B. & Ellis, T. GeneGuard: A modular plasmid system designed for biosafety. ACS Synth. Biol. 4, 307-316 (2015).
-
(2015)
ACS Synth. Biol.
, vol.4
, pp. 307-316
-
-
Wright, O.1
Delmans, M.2
Stan, G.B.3
Ellis, T.4
-
73
-
-
84966171881
-
Conditional suicide system for containment of bacteria and plasmids
-
Molin, S. et al. Conditional suicide system for containment of bacteria and plasmids. Nat. Biotechnol. 5, 1315-1318 (1987).
-
(1987)
Nat. Biotechnol.
, vol.5
, pp. 1315-1318
-
-
Molin, S.1
-
74
-
-
0023696645
-
Model suicide vector for containment of genetically engineered microorganisms
-
Bej, A. K., Perlin, M. H. & Atlas, R. M. Model suicide vector for containment of genetically engineered microorganisms. Appl. Environ. Microbiol. 54, 2472-2477 (1988).
-
(1988)
Appl. Environ. Microbiol.
, vol.54
, pp. 2472-2477
-
-
Bej, A.K.1
Perlin, M.H.2
Atlas, R.M.3
-
75
-
-
0025966530
-
Development of efficient suicide mechanisms for biological containment of bacteria
-
Knudsen, S. M. & Karlström, O. H. Development of efficient suicide mechanisms for biological containment of bacteria. Appl. Environ. Microbiol. 57, 85-92 (1991).
-
(1991)
Appl. Environ. Microbiol.
, vol.57
, pp. 85-92
-
-
Knudsen, S.M.1
Karlström, O.H.2
-
76
-
-
0024311086
-
A family of genes encoding a cell-killing function may be conserved in all gram-negative bacteria
-
Poulsen, L. K., Larsen, N. W., Molin, S. & Andersson, P. A family of genes encoding a cell-killing function may be conserved in all gram-negative bacteria. Mol. Microbiol. 3, 1463-1472 (1989).
-
(1989)
Mol. Microbiol.
, vol.3
, pp. 1463-1472
-
-
Poulsen, L.K.1
Larsen, N.W.2
Molin, S.3
Andersson, P.4
-
77
-
-
33744933432
-
A phase i trial with transgenic bacteria expressing interleukin-10 in Crohn's disease
-
Braat, H. et al. A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease. Clin. Gastroenterol. Hepatol. 4, 754-759 (2006).
-
(2006)
Clin. Gastroenterol. Hepatol.
, vol.4
, pp. 754-759
-
-
Braat, H.1
-
78
-
-
84870607623
-
Novel insights from hybrid LacI/GalR proteins: Family-wide functional attributes and biologically significant variation in transcription repression
-
Meinhardt, S. et al. Novel insights from hybrid LacI/GalR proteins: Family-wide functional attributes and biologically significant variation in transcription repression. Nucleic Acids Res. 40, 11139-11154 (2012).
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 11139-11154
-
-
Meinhardt, S.1
-
79
-
-
58149292217
-
Experimental identification of specificity determinants in the domain linker of a LacI/GalR protein: Bioinformaticsbased predictions generate true positives and false negatives
-
Meinhardt, S. & Swint-Kruse, L. Experimental identification of specificity determinants in the domain linker of a LacI/GalR protein: Bioinformaticsbased predictions generate true positives and false negatives. Proteins 73, 941-957 (2008).
-
(2008)
Proteins
, vol.73
, pp. 941-957
-
-
Meinhardt, S.1
Swint-Kruse, L.2
-
80
-
-
84956609810
-
Engineering an allosteric transcription factor to respond to new ligands
-
Taylor, N. D. et al. Engineering an allosteric transcription factor to respond to new ligands. Nat. Methods 13, 177-183 (2016).
-
(2016)
Nat. Methods
, vol.13
, pp. 177-183
-
-
Taylor, N.D.1
|