Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 8, 2017, Pages E1470-E1479

  Agmon, Neta ^a,b   Tang, Zuojian ^a   Yang, Kun ^b   Sutter, Ben ^c   Ikushima, Shigehito ^a,d   Cai, Yizhi ^b,e   Caravelli, Katrina ^b   Martin, James A ^a,b   Sun, Xiaoji ^a   Choi, Woo Jin ^b   Zhang, Allen ^b   Stracquadanio, Giovanni ^b,f   Hao, Haiping ^b   Tu, Benjamin P ^c   Fenyo, David ^a   Bader, Joel S ^b   Boeke, Jef D ^a,b  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d KIRIN HOLDINGS CO LTD   (Japan)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

^f UNIVERSITY OF ESSEX   (United Kingdom)

Author keywords

Escape mutants; Genome safety; Histone deacetylase; Rpd3L; Yeast

Indexed keywords

LIGAND;

ARTICLE; CONTROLLED STUDY; ESSENTIAL GENE; FUNGAL GENOME; FUNGUS GROWTH; GENE CONSTRUCT; GENETIC TRANSCRIPTION; GROWTH REGULATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REPRODUCTIVE FITNESS; SACCHAROMYCES CEREVISIAE; GENETICS; GENOME; METABOLIC ENGINEERING; PROCEDURES; REGULATOR GENE; SYNTHETIC BIOLOGY;

GENES, ESSENTIAL; GENOME; METABOLIC ENGINEERING; PROMOTER REGIONS, GENETIC; SACCHAROMYCES CEREVISIAE; SYNTHETIC BIOLOGY; TERMINATOR REGIONS, GENETIC; TRANSCRIPTION, GENETIC;

EID: 85013304603     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1621250114     Document Type: Article

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