-
1
-
-
84875851718
-
Preparing synthetic biology for the world
-
Moe-Behrens, G.H., Davis, R., Haynes, K.A. Preparing synthetic biology for the world. Front. Microbiol. 4, 5 (2013).
-
(2013)
Front. Microbiol.
, vol.4
, pp. 5
-
-
Moe-Behrens, G.H.1
Davis, R.2
Haynes, K.A.3
-
2
-
-
84884921451
-
Biomedically relevant circuit-design strategies in mammalian synthetic biology
-
Bacchus, W., Aubel, D., Fussenegger, M. Biomedically relevant circuit-design strategies in mammalian synthetic biology. Mol. Syst. Biol. 9, 691 (2013).
-
(2013)
Mol. Syst. Biol.
, vol.9
, pp. 691
-
-
Bacchus, W.1
Aubel, D.2
Fussenegger, M.3
-
3
-
-
84865283318
-
Post-translational tools expand the scope of synthetic biology
-
Olson, E.J., Tabor, J.J. Post-translational tools expand the scope of synthetic biology. Curr. Opin. Chem. Biol. 16, 300-306 (2012).
-
(2012)
Curr. Opin. Chem. Biol.
, vol.16
, pp. 300-306
-
-
Olson, E.J.1
Tabor, J.J.2
-
4
-
-
84925610163
-
Gene Guard: A modular plasmid system designed for biosafety
-
Wright, O., Delmans, M., Stan, G.B., Ellis, T. GeneGuard: a modular plasmid system designed for biosafety. ACS Synth. Biol. 4, 307-316 (2015).
-
(2015)
ACS Synth. Biol.
, vol.4
, pp. 307-316
-
-
Wright, O.1
Delmans, M.2
Stan, G.B.3
Ellis, T.4
-
5
-
-
84889685663
-
The centrality of RNA for engineering gene expression
-
Chappell, J. et al. The centrality of RNA for engineering gene expression. Biotechnol. J. 8, 1379-1395 (2013).
-
(2013)
Biotechnol. J.
, vol.8
, pp. 1379-1395
-
-
Chappell, J.1
-
6
-
-
84899079198
-
A brief history of synthetic biology
-
Cameron, D.E., Bashor, C.J., Collins, J.J. A brief history of synthetic biology. Nat. Rev. Microbiol. 12, 381-390 (2014).
-
(2014)
Nat. Rev. Microbiol.
, vol.12
, pp. 381-390
-
-
Cameron, D.E.1
Bashor, C.J.2
Collins, J.J.3
-
7
-
-
84879816810
-
Building-in biosafety for synthetic biology
-
Wright, O., Stan, G.B., Ellis, T. Building-in biosafety for synthetic biology. Microbiology 159, 1221-1235 (2013).
-
(2013)
Microbiology
, vol.159
, pp. 1221-1235
-
-
Wright, O.1
Stan, G.B.2
Ellis, T.3
-
8
-
-
0037820426
-
Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10
-
Steidler, L. et al. Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10. Nat. Biotechnol. 21, 785-789 (2003).
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 785-789
-
-
Steidler, L.1
-
9
-
-
84922595374
-
Recoded organisms engineered to depend on synthetic amino acids
-
Rovner, A.J. et al. Recoded organisms engineered to depend on synthetic amino acids. Nature 518, 89-93 (2015).
-
(2015)
Nature
, vol.518
, pp. 89-93
-
-
Rovner, A.J.1
-
10
-
-
84923112573
-
Biocontainment of genetically modified organisms by synthetic protein design
-
Mandell, D.J. et al. Biocontainment of genetically modified organisms by synthetic protein design. Nature 518, 55-60 (2015).
-
(2015)
Nature
, vol.518
, pp. 55-60
-
-
Mandell, D.J.1
-
11
-
-
77957679279
-
Tracking tuning, and terminating microbial physiology using synthetic riboregulators
-
Callura, J.M., Dwyer, D.J., Isaacs, F.J., Cantor, C.R., Collins, J.J. Tracking, tuning, and terminating microbial physiology using synthetic riboregulators. Proc. Natl. Acad. Sci. USA 107, 15898-15903 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 15898-15903
-
-
Callura, J.M.1
Dwyer, D.J.2
Isaacs, F.J.3
Cantor, C.R.4
Collins, J.J.5
-
12
-
-
0025754177
-
Conditional-suicide containment system for bacteria which mineralize aromatics
-
Contreras, A., Molin, S., Ramos, J.L. Conditional-suicide containment system for bacteria which mineralize aromatics. Appl. Environ. Microbiol. 57, 1504-1508 (1991).
-
(1991)
Appl. Environ. Microbiol.
, vol.57
, pp. 1504-1508
-
-
Contreras, A.1
Molin, S.2
Ramos, J.L.3
-
13
-
-
84922678329
-
Intrinsic biocontainment: Multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes
-
Cai, Y. et al. Intrinsic biocontainment: multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes. Proc. Natl. Acad. Sci. USA 112, 1803-1808 (2015).
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. 1803-1808
-
-
Cai, Y.1
-
14
-
-
84922664743
-
Multilayered genetic safeguards limit growth of microorganisms to defined environments
-
Gallagher, R.R., Patel, J.R., Interiano, A.L., Rovner, A.J., Isaacs, F.J. Multilayered genetic safeguards limit growth of microorganisms to defined environments. Nucleic Acids Res. 43, 1945-1954 (2015).
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. 1945-1954
-
-
Gallagher, R.R.1
Patel, J.R.2
Interiano, A.L.3
Rovner, A.J.4
Isaacs, F.J.5
-
15
-
-
33748953866
-
Genetic parts to program bacteria
-
Voigt, C.A. Genetic parts to program bacteria. Curr. Opin. Biotechnol. 17, 548-557 (2006).
-
(2006)
Curr. Opin. Biotechnol.
, vol.17
, pp. 548-557
-
-
Voigt, C.A.1
-
16
-
-
0027368820
-
A substrate-dependent biological containment system for Pseudomonas putida based on the Escherichia coli gef gene
-
Jensen, L.B., Ramos, J.L., Kaneva, Z., Molin, S. A substrate-dependent biological containment system for Pseudomonas putida based on the Escherichia coli gef gene. Appl. Environ. Microbiol. 59, 3713-3717 (1993).
-
(1993)
Appl. Environ. Microbiol.
, vol.59
, pp. 3713-3717
-
-
Jensen, L.B.1
Ramos, J.L.2
Kaneva, Z.3
Molin, S.4
-
17
-
-
84869078490
-
Iterative plug-and-play methodology for constructing and modifying synthetic gene networks
-
Litcofsky, K.D., Afeyan, R.B., Krom, R.J., Khalil, A.S., Collins, J.J. Iterative plug-and-play methodology for constructing and modifying synthetic gene networks. Nat. Methods 9, 1077-1080 (2012).
-
(2012)
Nat. Methods
, vol.9
, pp. 1077-1080
-
-
Litcofsky, K.D.1
Afeyan, R.B.2
Krom, R.J.3
Khalil, A.S.4
Collins, J.J.5
-
18
-
-
0034688174
-
Construction of a genetic toggle switch in Escherichia coli
-
Gardner, T.S., Cantor, C.R., Collins, J.J. Construction of a genetic toggle switch in Escherichia coli. Nature 403, 339-342 (2000).
-
(2000)
Nature
, vol.403
, pp. 339-342
-
-
Gardner, T.S.1
Cantor, C.R.2
Collins, J.J.3
-
19
-
-
0342687610
-
A perfectly symmetric lac operator binds the lac repressor very tightly
-
Sadler, J.R., Sasmor, H., Betz, J.L. A perfectly symmetric lac operator binds the lac repressor very tightly. Proc. Natl. Acad. Sci. USA 80, 6785-6789 (1983).
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 6785-6789
-
-
Sadler, J.R.1
Sasmor, H.2
Betz, J.L.3
-
20
-
-
84924336011
-
Tunable protein degradation in bacteria
-
Cameron, D.E., Collins, J.J. Tunable protein degradation in bacteria. Nat. Biotechnol. 32, 1276-1281 (2014).
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 1276-1281
-
-
Cameron, D.E.1
Collins, J.J.2
-
21
-
-
0021161793
-
Isolation of gram quantities of EcoRI restriction and modification enzymes from an overproducing strain
-
Cheng, S.C., Kim, R., King, K., Kim, S.H., Modrich, P. Isolation of gram quantities of EcoRI restriction and modification enzymes from an overproducing strain. J. Biol. Chem. 259, 11571-11575 (1984).
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 11571-11575
-
-
Cheng, S.C.1
Kim, R.2
King, K.3
Kim, S.H.4
Modrich, P.5
-
22
-
-
33750206130
-
A strand-passage conformation of DNA gyrase is required to allow the bacterial toxin, CcdB, to access its binding site
-
Smith, A.B., Maxwell, A. A strand-passage conformation of DNA gyrase is required to allow the bacterial toxin, CcdB, to access its binding site. Nucleic Acids Res. 34, 4667-4676 (2006).
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 4667-4676
-
-
Smith, A.B.1
Maxwell, A.2
-
23
-
-
0242361323
-
MazF cleaves cellular mRNAs specifically at ACA to block protein synthesis in Escherichia coli
-
Zhang, Y. et al. MazF cleaves cellular mRNAs specifically at ACA to block protein synthesis in Escherichia coli. Mol. Cell 12, 913-923 (2003).
-
(2003)
Mol. Cell
, vol.12
, pp. 913-923
-
-
Zhang, Y.1
-
24
-
-
79957534528
-
The ribosome binding site calculator
-
Salis, H.M. The ribosome binding site calculator. Methods Enzymol. 498, 19-42 (2011).
-
(2011)
Methods Enzymol.
, vol.498
, pp. 19-42
-
-
Salis, H.M.1
-
25
-
-
58149292217
-
Experimental identification of specificity determinants in the domain linker of a LacI/GalR protein: Bioinformatics-based predictions generate true positives and false negatives
-
Meinhardt, S., Swint-Kruse, L. Experimental identification of specificity determinants in the domain linker of a LacI/GalR protein: bioinformatics-based predictions generate true positives and false negatives. Proteins 73, 941-957 (2008).
-
(2008)
Proteins
, vol.73
, pp. 941-957
-
-
Meinhardt, S.1
Swint-Kruse, L.2
-
26
-
-
84870607623
-
Novel insights from hybrid LacI/GalR proteins: Family-wide functional attributes and biologically significant variation in transcription repression
-
Meinhardt, S. et al. Novel insights from hybrid LacI/GalR proteins: family-wide functional attributes and biologically significant variation in transcription repression. Nucleic Acids Res. 40, 11139-11154 (2012).
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 11139-11154
-
-
Meinhardt, S.1
-
27
-
-
84927591028
-
Modular multi-input transcriptional logic gating with orthogonal LacI/GalR family chimeras
-
Shis, D.L., Hussain, F., Meinhardt, S., Swint-Kruse, L., Bennett, M.R. Modular, multi-input transcriptional logic gating with orthogonal LacI/GalR family chimeras. ACS Synth. Biol. 3, 645-651 (2014).
-
(2014)
ACS Synth. Biol.
, vol.3
, pp. 645-651
-
-
Shis, D.L.1
Hussain, F.2
Meinhardt, S.3
Swint-Kruse, L.4
Bennett, M.R.5
-
28
-
-
84891914165
-
Rates of transposition in Escherichia coli
-
Sousa, A., Bourgard, C., Wahl, L.M., Gordo, I. Rates of transposition in Escherichia coli. Biol. Lett. 9, 20130838 (2013).
-
(2013)
Biol. Lett.
, vol.9
, pp. 20130838
-
-
Sousa, A.1
Bourgard, C.2
Wahl, L.M.3
Gordo, I.4
-
30
-
-
84891782659
-
Pfam: The protein families database
-
Finn, R.D. et al. Pfam: the protein families database. Nucleic Acids Res. 42, D222-D230 (2014).
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. D222-D230
-
-
Finn, R.D.1
-
31
-
-
20544432535
-
The TetR family of transcriptional repressors
-
Ramos, J.L. et al. The TetR family of transcriptional repressors. Microbiol. Mol. Biol. Rev. 69, 326-356 (2005).
-
(2005)
Microbiol. Mol. Biol. Rev.
, vol.69
, pp. 326-356
-
-
Ramos, J.L.1
-
32
-
-
0028836985
-
Expression vectors for the use of eukaryotic luciferases as bacterial markers with different colors of luminescence
-
Cebolla, A., Vázquez, M.E., Palomares, A.J. Expression vectors for the use of eukaryotic luciferases as bacterial markers with different colors of luminescence. Appl. Environ. Microbiol. 61, 660-668 (1995).
-
(1995)
Appl. Environ. Microbiol.
, vol.61
, pp. 660-668
-
-
Cebolla, A.1
Vázquez, M.E.2
Palomares, A.J.3
-
33
-
-
84946095546
-
Antibiotic-free selection in biotherapeutics: Now and forever
-
Mignon, C., Sodoyer, R., Werle, B. Antibiotic-free selection in biotherapeutics: now and forever. Pathogens 4, 157-181 (2015).
-
(2015)
Pathogens
, vol.4
, pp. 157-181
-
-
Mignon, C.1
Sodoyer, R.2
Werle, B.3
-
34
-
-
84857114878
-
Low-mutation-rate reduced-genome Escherichia coli: An improved host for faithful maintenance of engineered genetic constructs
-
Csörgo, B., Fehér, T., Tímár, E., Blattner, F.R., Pósfai, G. Low-mutation-rate, reduced-genome Escherichia coli: an improved host for faithful maintenance of engineered genetic constructs. Microb. Cell Fact. 11, 11 (2012).
-
(2012)
Microb. Cell Fact.
, vol.11
, pp. 11
-
-
Csörgo, B.1
Fehér, T.2
Tímár, E.3
Blattner, F.R.4
Pósfai, G.5
-
35
-
-
36448991500
-
Clustal W and Clustal X version 2.0
-
Larkin, M.A. et al. Clustal W and Clustal X version 2.0. Bioinformatics 23, 2947-2948 (2007).
-
(2007)
Bioinformatics
, vol.23
, pp. 2947-2948
-
-
Larkin, M.A.1
-
36
-
-
0034089394
-
A closer view of the conformation of the Lac repressor bound to operator
-
Bell, C.E., Lewis, M. A closer view of the conformation of the Lac repressor bound to operator. Nat. Struct. Biol. 7, 209-214 (2000).
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 209-214
-
-
Bell, C.E.1
Lewis, M.2
-
37
-
-
0029004903
-
Crystal structure of lac repressor core tetramer and its implications for DNA looping
-
Friedman, A.M., Fischmann, T.O., Steitz, T.A. Crystal structure of lac repressor core tetramer and its implications for DNA looping. Science 268, 1721-1727 (1995).
-
(1995)
Science
, vol.268
, pp. 1721-1727
-
-
Friedman, A.M.1
Fischmann, T.O.2
Steitz, T.A.3
-
38
-
-
0029938053
-
Crystal structure of the lactose operon repressor and its complexes with DNA and inducer
-
Lewis, M. et al. Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Science 271, 1247-1254 (1996).
-
(1996)
Science
, vol.271
, pp. 1247-1254
-
-
Lewis, M.1
-
39
-
-
0028810684
-
Mechanism of corepressor-mediated specific DNA binding by the purine repressor
-
Schumacher, M.A., Choi, K.Y., Lu, F., Zalkin, H., Brennan, R.G. Mechanism of corepressor-mediated specific DNA binding by the purine repressor. Cell 83, 147-155 (1995).
-
(1995)
Cell
, vol.83
, pp. 147-155
-
-
Schumacher, M.A.1
Choi, K.Y.2
Lu, F.3
Zalkin, H.4
Brennan, R.G.5
-
40
-
-
0032804235
-
The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions
-
Glasfeld, A., Koehler, A.N., Schumacher, M.A., Brennan, R.G. The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. J. Mol. Biol. 291, 347-361 (1999).
-
(1999)
J. Mol. Biol.
, vol.291
, pp. 347-361
-
-
Glasfeld, A.1
Koehler, A.N.2
Schumacher, M.A.3
Brennan, R.G.4
-
41
-
-
31544450286
-
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: The Keio collection
-
Baba, T. et al. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2, 2006.0008 (2006).
-
(2006)
Mol. Syst. Biol.
, vol.2
, pp. 2006-2008
-
-
Baba, T.1
-
42
-
-
0034612342
-
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
-
Datsenko, K.A., Wanner, B.L. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. USA 97, 6640-6645 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6640-6645
-
-
Datsenko, K.A.1
Wanner, B.L.2
-
44
-
-
67349270900
-
Enzymatic assembly of DNA molecules up to several hundred kilobases
-
Gibson, D.G. et al. Enzymatic assembly of DNA molecules up to several hundred kilobases. Nat. Methods 6, 343-345 (2009).
-
(2009)
Nat. Methods
, vol.6
, pp. 343-345
-
-
Gibson, D.G.1
-
45
-
-
0036739377
-
Conditionally amplifiable BACs: Switching from single-copy to high-copy vectors and genomic clones
-
Wild, J., Hradecna, Z., Szybalski, W. Conditionally amplifiable BACs: switching from single-copy to high-copy vectors and genomic clones. Genome Res. 12, 1434-1444 (2002).
-
(2002)
Genome Res.
, vol.12
, pp. 1434-1444
-
-
Wild, J.1
Hradecna, Z.2
Szybalski, W.3
-
46
-
-
0030861452
-
Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements
-
Lutz, R., Bujard, H. Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements. Nucleic Acids Res. 25, 1203-1210 (1997).
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 1203-1210
-
-
Lutz, R.1
Bujard, H.2
|