메뉴 건너뛰기




Volumn 12, Issue 2, 2016, Pages 82-86

'Deadman' and 'Passcode' microbial kill switches for bacterial containment

Author keywords

[No Author keywords available]

Indexed keywords

SYNTHETIC DNA; BACTERIAL TOXIN;

EID: 84955192252     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1979     Document Type: Article
Times cited : (241)

References (46)
  • 2
    • 84884921451 scopus 로고    scopus 로고
    • Biomedically relevant circuit-design strategies in mammalian synthetic biology
    • Bacchus, W., Aubel, D., Fussenegger, M. Biomedically relevant circuit-design strategies in mammalian synthetic biology. Mol. Syst. Biol. 9, 691 (2013).
    • (2013) Mol. Syst. Biol. , vol.9 , pp. 691
    • Bacchus, W.1    Aubel, D.2    Fussenegger, M.3
  • 3
    • 84865283318 scopus 로고    scopus 로고
    • Post-translational tools expand the scope of synthetic biology
    • Olson, E.J., Tabor, J.J. Post-translational tools expand the scope of synthetic biology. Curr. Opin. Chem. Biol. 16, 300-306 (2012).
    • (2012) Curr. Opin. Chem. Biol. , vol.16 , pp. 300-306
    • Olson, E.J.1    Tabor, J.J.2
  • 4
    • 84925610163 scopus 로고    scopus 로고
    • Gene Guard: A modular plasmid system designed for biosafety
    • Wright, O., Delmans, M., Stan, G.B., Ellis, T. GeneGuard: a modular plasmid system designed for biosafety. ACS Synth. Biol. 4, 307-316 (2015).
    • (2015) ACS Synth. Biol. , vol.4 , pp. 307-316
    • Wright, O.1    Delmans, M.2    Stan, G.B.3    Ellis, T.4
  • 5
    • 84889685663 scopus 로고    scopus 로고
    • The centrality of RNA for engineering gene expression
    • Chappell, J. et al. The centrality of RNA for engineering gene expression. Biotechnol. J. 8, 1379-1395 (2013).
    • (2013) Biotechnol. J. , vol.8 , pp. 1379-1395
    • Chappell, J.1
  • 7
    • 84879816810 scopus 로고    scopus 로고
    • Building-in biosafety for synthetic biology
    • Wright, O., Stan, G.B., Ellis, T. Building-in biosafety for synthetic biology. Microbiology 159, 1221-1235 (2013).
    • (2013) Microbiology , vol.159 , pp. 1221-1235
    • Wright, O.1    Stan, G.B.2    Ellis, T.3
  • 8
    • 0037820426 scopus 로고    scopus 로고
    • Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10
    • Steidler, L. et al. Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10. Nat. Biotechnol. 21, 785-789 (2003).
    • (2003) Nat. Biotechnol. , vol.21 , pp. 785-789
    • Steidler, L.1
  • 9
    • 84922595374 scopus 로고    scopus 로고
    • Recoded organisms engineered to depend on synthetic amino acids
    • Rovner, A.J. et al. Recoded organisms engineered to depend on synthetic amino acids. Nature 518, 89-93 (2015).
    • (2015) Nature , vol.518 , pp. 89-93
    • Rovner, A.J.1
  • 10
    • 84923112573 scopus 로고    scopus 로고
    • Biocontainment of genetically modified organisms by synthetic protein design
    • Mandell, D.J. et al. Biocontainment of genetically modified organisms by synthetic protein design. Nature 518, 55-60 (2015).
    • (2015) Nature , vol.518 , pp. 55-60
    • Mandell, D.J.1
  • 12
    • 0025754177 scopus 로고
    • Conditional-suicide containment system for bacteria which mineralize aromatics
    • Contreras, A., Molin, S., Ramos, J.L. Conditional-suicide containment system for bacteria which mineralize aromatics. Appl. Environ. Microbiol. 57, 1504-1508 (1991).
    • (1991) Appl. Environ. Microbiol. , vol.57 , pp. 1504-1508
    • Contreras, A.1    Molin, S.2    Ramos, J.L.3
  • 13
    • 84922678329 scopus 로고    scopus 로고
    • Intrinsic biocontainment: Multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes
    • Cai, Y. et al. Intrinsic biocontainment: multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes. Proc. Natl. Acad. Sci. USA 112, 1803-1808 (2015).
    • (2015) Proc. Natl. Acad. Sci. USA , vol.112 , pp. 1803-1808
    • Cai, Y.1
  • 14
    • 84922664743 scopus 로고    scopus 로고
    • Multilayered genetic safeguards limit growth of microorganisms to defined environments
    • Gallagher, R.R., Patel, J.R., Interiano, A.L., Rovner, A.J., Isaacs, F.J. Multilayered genetic safeguards limit growth of microorganisms to defined environments. Nucleic Acids Res. 43, 1945-1954 (2015).
    • (2015) Nucleic Acids Res. , vol.43 , pp. 1945-1954
    • Gallagher, R.R.1    Patel, J.R.2    Interiano, A.L.3    Rovner, A.J.4    Isaacs, F.J.5
  • 15
    • 33748953866 scopus 로고    scopus 로고
    • Genetic parts to program bacteria
    • Voigt, C.A. Genetic parts to program bacteria. Curr. Opin. Biotechnol. 17, 548-557 (2006).
    • (2006) Curr. Opin. Biotechnol. , vol.17 , pp. 548-557
    • Voigt, C.A.1
  • 16
    • 0027368820 scopus 로고
    • A substrate-dependent biological containment system for Pseudomonas putida based on the Escherichia coli gef gene
    • Jensen, L.B., Ramos, J.L., Kaneva, Z., Molin, S. A substrate-dependent biological containment system for Pseudomonas putida based on the Escherichia coli gef gene. Appl. Environ. Microbiol. 59, 3713-3717 (1993).
    • (1993) Appl. Environ. Microbiol. , vol.59 , pp. 3713-3717
    • Jensen, L.B.1    Ramos, J.L.2    Kaneva, Z.3    Molin, S.4
  • 17
    • 84869078490 scopus 로고    scopus 로고
    • Iterative plug-and-play methodology for constructing and modifying synthetic gene networks
    • Litcofsky, K.D., Afeyan, R.B., Krom, R.J., Khalil, A.S., Collins, J.J. Iterative plug-and-play methodology for constructing and modifying synthetic gene networks. Nat. Methods 9, 1077-1080 (2012).
    • (2012) Nat. Methods , vol.9 , pp. 1077-1080
    • Litcofsky, K.D.1    Afeyan, R.B.2    Krom, R.J.3    Khalil, A.S.4    Collins, J.J.5
  • 18
    • 0034688174 scopus 로고    scopus 로고
    • Construction of a genetic toggle switch in Escherichia coli
    • Gardner, T.S., Cantor, C.R., Collins, J.J. Construction of a genetic toggle switch in Escherichia coli. Nature 403, 339-342 (2000).
    • (2000) Nature , vol.403 , pp. 339-342
    • Gardner, T.S.1    Cantor, C.R.2    Collins, J.J.3
  • 19
    • 0342687610 scopus 로고
    • A perfectly symmetric lac operator binds the lac repressor very tightly
    • Sadler, J.R., Sasmor, H., Betz, J.L. A perfectly symmetric lac operator binds the lac repressor very tightly. Proc. Natl. Acad. Sci. USA 80, 6785-6789 (1983).
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 6785-6789
    • Sadler, J.R.1    Sasmor, H.2    Betz, J.L.3
  • 20
    • 84924336011 scopus 로고    scopus 로고
    • Tunable protein degradation in bacteria
    • Cameron, D.E., Collins, J.J. Tunable protein degradation in bacteria. Nat. Biotechnol. 32, 1276-1281 (2014).
    • (2014) Nat. Biotechnol. , vol.32 , pp. 1276-1281
    • Cameron, D.E.1    Collins, J.J.2
  • 21
    • 0021161793 scopus 로고
    • Isolation of gram quantities of EcoRI restriction and modification enzymes from an overproducing strain
    • Cheng, S.C., Kim, R., King, K., Kim, S.H., Modrich, P. Isolation of gram quantities of EcoRI restriction and modification enzymes from an overproducing strain. J. Biol. Chem. 259, 11571-11575 (1984).
    • (1984) J. Biol. Chem. , vol.259 , pp. 11571-11575
    • Cheng, S.C.1    Kim, R.2    King, K.3    Kim, S.H.4    Modrich, P.5
  • 22
    • 33750206130 scopus 로고    scopus 로고
    • A strand-passage conformation of DNA gyrase is required to allow the bacterial toxin, CcdB, to access its binding site
    • Smith, A.B., Maxwell, A. A strand-passage conformation of DNA gyrase is required to allow the bacterial toxin, CcdB, to access its binding site. Nucleic Acids Res. 34, 4667-4676 (2006).
    • (2006) Nucleic Acids Res. , vol.34 , pp. 4667-4676
    • Smith, A.B.1    Maxwell, A.2
  • 23
    • 0242361323 scopus 로고    scopus 로고
    • MazF cleaves cellular mRNAs specifically at ACA to block protein synthesis in Escherichia coli
    • Zhang, Y. et al. MazF cleaves cellular mRNAs specifically at ACA to block protein synthesis in Escherichia coli. Mol. Cell 12, 913-923 (2003).
    • (2003) Mol. Cell , vol.12 , pp. 913-923
    • Zhang, Y.1
  • 24
    • 79957534528 scopus 로고    scopus 로고
    • The ribosome binding site calculator
    • Salis, H.M. The ribosome binding site calculator. Methods Enzymol. 498, 19-42 (2011).
    • (2011) Methods Enzymol. , vol.498 , pp. 19-42
    • Salis, H.M.1
  • 25
    • 58149292217 scopus 로고    scopus 로고
    • Experimental identification of specificity determinants in the domain linker of a LacI/GalR protein: Bioinformatics-based predictions generate true positives and false negatives
    • Meinhardt, S., Swint-Kruse, L. Experimental identification of specificity determinants in the domain linker of a LacI/GalR protein: bioinformatics-based predictions generate true positives and false negatives. Proteins 73, 941-957 (2008).
    • (2008) Proteins , vol.73 , pp. 941-957
    • Meinhardt, S.1    Swint-Kruse, L.2
  • 26
    • 84870607623 scopus 로고    scopus 로고
    • Novel insights from hybrid LacI/GalR proteins: Family-wide functional attributes and biologically significant variation in transcription repression
    • Meinhardt, S. et al. Novel insights from hybrid LacI/GalR proteins: family-wide functional attributes and biologically significant variation in transcription repression. Nucleic Acids Res. 40, 11139-11154 (2012).
    • (2012) Nucleic Acids Res. , vol.40 , pp. 11139-11154
    • Meinhardt, S.1
  • 27
    • 84927591028 scopus 로고    scopus 로고
    • Modular multi-input transcriptional logic gating with orthogonal LacI/GalR family chimeras
    • Shis, D.L., Hussain, F., Meinhardt, S., Swint-Kruse, L., Bennett, M.R. Modular, multi-input transcriptional logic gating with orthogonal LacI/GalR family chimeras. ACS Synth. Biol. 3, 645-651 (2014).
    • (2014) ACS Synth. Biol. , vol.3 , pp. 645-651
    • Shis, D.L.1    Hussain, F.2    Meinhardt, S.3    Swint-Kruse, L.4    Bennett, M.R.5
  • 28
    • 84891914165 scopus 로고    scopus 로고
    • Rates of transposition in Escherichia coli
    • Sousa, A., Bourgard, C., Wahl, L.M., Gordo, I. Rates of transposition in Escherichia coli. Biol. Lett. 9, 20130838 (2013).
    • (2013) Biol. Lett. , vol.9 , pp. 20130838
    • Sousa, A.1    Bourgard, C.2    Wahl, L.M.3    Gordo, I.4
  • 30
    • 84891782659 scopus 로고    scopus 로고
    • Pfam: The protein families database
    • Finn, R.D. et al. Pfam: the protein families database. Nucleic Acids Res. 42, D222-D230 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. D222-D230
    • Finn, R.D.1
  • 31
    • 20544432535 scopus 로고    scopus 로고
    • The TetR family of transcriptional repressors
    • Ramos, J.L. et al. The TetR family of transcriptional repressors. Microbiol. Mol. Biol. Rev. 69, 326-356 (2005).
    • (2005) Microbiol. Mol. Biol. Rev. , vol.69 , pp. 326-356
    • Ramos, J.L.1
  • 32
    • 0028836985 scopus 로고
    • Expression vectors for the use of eukaryotic luciferases as bacterial markers with different colors of luminescence
    • Cebolla, A., Vázquez, M.E., Palomares, A.J. Expression vectors for the use of eukaryotic luciferases as bacterial markers with different colors of luminescence. Appl. Environ. Microbiol. 61, 660-668 (1995).
    • (1995) Appl. Environ. Microbiol. , vol.61 , pp. 660-668
    • Cebolla, A.1    Vázquez, M.E.2    Palomares, A.J.3
  • 33
    • 84946095546 scopus 로고    scopus 로고
    • Antibiotic-free selection in biotherapeutics: Now and forever
    • Mignon, C., Sodoyer, R., Werle, B. Antibiotic-free selection in biotherapeutics: now and forever. Pathogens 4, 157-181 (2015).
    • (2015) Pathogens , vol.4 , pp. 157-181
    • Mignon, C.1    Sodoyer, R.2    Werle, B.3
  • 34
    • 84857114878 scopus 로고    scopus 로고
    • Low-mutation-rate reduced-genome Escherichia coli: An improved host for faithful maintenance of engineered genetic constructs
    • Csörgo, B., Fehér, T., Tímár, E., Blattner, F.R., Pósfai, G. Low-mutation-rate, reduced-genome Escherichia coli: an improved host for faithful maintenance of engineered genetic constructs. Microb. Cell Fact. 11, 11 (2012).
    • (2012) Microb. Cell Fact. , vol.11 , pp. 11
    • Csörgo, B.1    Fehér, T.2    Tímár, E.3    Blattner, F.R.4    Pósfai, G.5
  • 35
    • 36448991500 scopus 로고    scopus 로고
    • Clustal W and Clustal X version 2.0
    • Larkin, M.A. et al. Clustal W and Clustal X version 2.0. Bioinformatics 23, 2947-2948 (2007).
    • (2007) Bioinformatics , vol.23 , pp. 2947-2948
    • Larkin, M.A.1
  • 36
    • 0034089394 scopus 로고    scopus 로고
    • A closer view of the conformation of the Lac repressor bound to operator
    • Bell, C.E., Lewis, M. A closer view of the conformation of the Lac repressor bound to operator. Nat. Struct. Biol. 7, 209-214 (2000).
    • (2000) Nat. Struct. Biol. , vol.7 , pp. 209-214
    • Bell, C.E.1    Lewis, M.2
  • 37
    • 0029004903 scopus 로고
    • Crystal structure of lac repressor core tetramer and its implications for DNA looping
    • Friedman, A.M., Fischmann, T.O., Steitz, T.A. Crystal structure of lac repressor core tetramer and its implications for DNA looping. Science 268, 1721-1727 (1995).
    • (1995) Science , vol.268 , pp. 1721-1727
    • Friedman, A.M.1    Fischmann, T.O.2    Steitz, T.A.3
  • 38
    • 0029938053 scopus 로고    scopus 로고
    • Crystal structure of the lactose operon repressor and its complexes with DNA and inducer
    • Lewis, M. et al. Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Science 271, 1247-1254 (1996).
    • (1996) Science , vol.271 , pp. 1247-1254
    • Lewis, M.1
  • 39
    • 0028810684 scopus 로고
    • Mechanism of corepressor-mediated specific DNA binding by the purine repressor
    • Schumacher, M.A., Choi, K.Y., Lu, F., Zalkin, H., Brennan, R.G. Mechanism of corepressor-mediated specific DNA binding by the purine repressor. Cell 83, 147-155 (1995).
    • (1995) Cell , vol.83 , pp. 147-155
    • Schumacher, M.A.1    Choi, K.Y.2    Lu, F.3    Zalkin, H.4    Brennan, R.G.5
  • 40
    • 0032804235 scopus 로고    scopus 로고
    • The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions
    • Glasfeld, A., Koehler, A.N., Schumacher, M.A., Brennan, R.G. The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. J. Mol. Biol. 291, 347-361 (1999).
    • (1999) J. Mol. Biol. , vol.291 , pp. 347-361
    • Glasfeld, A.1    Koehler, A.N.2    Schumacher, M.A.3    Brennan, R.G.4
  • 41
    • 31544450286 scopus 로고    scopus 로고
    • Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: The Keio collection
    • Baba, T. et al. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2, 2006.0008 (2006).
    • (2006) Mol. Syst. Biol. , vol.2 , pp. 2006-2008
    • Baba, T.1
  • 42
    • 0034612342 scopus 로고    scopus 로고
    • One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
    • Datsenko, K.A., Wanner, B.L. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. USA 97, 6640-6645 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6640-6645
    • Datsenko, K.A.1    Wanner, B.L.2
  • 44
    • 67349270900 scopus 로고    scopus 로고
    • Enzymatic assembly of DNA molecules up to several hundred kilobases
    • Gibson, D.G. et al. Enzymatic assembly of DNA molecules up to several hundred kilobases. Nat. Methods 6, 343-345 (2009).
    • (2009) Nat. Methods , vol.6 , pp. 343-345
    • Gibson, D.G.1
  • 45
    • 0036739377 scopus 로고    scopus 로고
    • Conditionally amplifiable BACs: Switching from single-copy to high-copy vectors and genomic clones
    • Wild, J., Hradecna, Z., Szybalski, W. Conditionally amplifiable BACs: switching from single-copy to high-copy vectors and genomic clones. Genome Res. 12, 1434-1444 (2002).
    • (2002) Genome Res. , vol.12 , pp. 1434-1444
    • Wild, J.1    Hradecna, Z.2    Szybalski, W.3
  • 46
    • 0030861452 scopus 로고    scopus 로고
    • Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements
    • Lutz, R., Bujard, H. Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements. Nucleic Acids Res. 25, 1203-1210 (1997).
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1203-1210
    • Lutz, R.1    Bujard, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.