Recoded organisms engineered to depend on synthetic amino acids

Nature

Volumn 518, Issue 7537, 2015, Pages 89-93

  Rovner, Alexis J ^a   Haimovich, Adrian D ^a   Katz, Spencer R ^a   Li, Zhe ^a   Grome, Michael W ^a   Gassaway, Brandon M ^a,b   Amiram, Miriam ^a   Patel, Jaymin R ^a   Gallagher, Ryan R ^a   Rinehart, Jesse ^a,b   Isaacs, Farren J ^a  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; PHENYLALANINE; TRANSFER RNA; AMINO ACID TRANSFER RNA LIGASE; CODON; CULTURE MEDIUM; ESCHERICHIA COLI PROTEIN; PRFA PROTEIN, E COLI; TRANSLATION TERMINATION FACTOR;

AMINO ACID; BACTERIUM; BIOENGINEERING; BIOREMEDIATION; BIOSAFETY; GENE EXPRESSION; GENETIC ISOLATION; GENETICALLY MODIFIED ORGANISM; MUTATION; PROBIOTICS; RECOMBINATION;

AMINO ACID SYNTHESIS; ARTICLE; AUXOTROPHY; CHROMOSOME; CODON; CONTROLLED STUDY; ESCHERICHIA COLI; ESSENTIAL GENE; GENE ISOLATION; GENETIC CODE; GENETIC ENGINEERING; GENOMICALLY RECODED ORGANISM; HORIZONTAL GENE TRANSFER; METHANOCALDOCOCCUS JANNASCHII; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC ORGANISM; BACTERIAL GENOME; BIOSYNTHESIS; CHEMISTRY; CULTURE MEDIUM; CYTOLOGY; DRUG EFFECTS; ENVIRONMENT; ENZYME ACTIVE SITE; GENETICS; GROWTH, DEVELOPMENT AND AGING; HAZARDOUS WASTE; METABOLISM; MICROBIAL VIABILITY; MOLECULAR EVOLUTION; MOLECULAR GENETICS; PHARMACOLOGY; PROCEDURES; PROTEIN MULTIMERIZATION; SYNTHESIS; SYNTHETIC BIOLOGY;

ESCHERICHIA COLI; METHANOCALDOCOCCUS JANNASCHII;

AMINO ACIDS; AMINO ACYL-TRNA SYNTHETASES; CATALYTIC DOMAIN; CODON; CONTAINMENT OF BIOHAZARDS; CULTURE MEDIA; ENVIRONMENT; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; EVOLUTION, MOLECULAR; GENE TRANSFER, HORIZONTAL; GENES, ESSENTIAL; GENETIC CODE; GENETIC ENGINEERING; GENOME, BACTERIAL; MICROBIAL VIABILITY; MOLECULAR SEQUENCE DATA; ORGANISMS, GENETICALLY MODIFIED; PEPTIDE TERMINATION FACTORS; PHENYLALANINE; PROTEIN MULTIMERIZATION; RNA, TRANSFER; SYNTHETIC BIOLOGY;

EID: 84922595374     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14095     Document Type: Article

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