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Volumn 26, Issue , 2018, Pages 97-121

The Oxazolidinones

Author keywords

Chloramphenicol; Peptidyl transfer center; Protein synthesis inhibitor; Ribosome; Sutezolid

Indexed keywords

CADAZOLID; CHLORAMPHENICOL; CONTEZOLID; CONTEZOLID ACEFOSAMIL; DP 326; FLORFENICOL; LINEZOLID; OXAZOLIDINONE DERIVATIVE; PF 2341272; POSIZOLID; RADEZOLID; RBX 11760; RIVAROXABAN; SEROTONIN UPTAKE INHIBITOR; SIDEROPHORE; SUTEZOLID; T 145; TEDIZOLID; TETRAMETHYLPYRAZINE; TOLOXATONE; UNCLASSIFIED DRUG; VANCOMYCIN;

EID: 85046789610     PISSN: 18622461     EISSN: 1862247X     Source Type: Book Series    
DOI: 10.1007/7355_2017_15     Document Type: Chapter
Times cited : (16)

References (106)
  • 1
    • 41849111626 scopus 로고    scopus 로고
    • YVOX®), the first member of a completely new class of antibacterial agents for the treatment of serious gram-positive infections
    • YVOX®), the first member of a completely new class of antibacterial agents for the treatment of serious gram-positive infections. J Med Chem 51:1981–1990. doi:10.1021/jm800038g
    • (2008) J Med Chem , vol.51 , pp. 1981-1990
    • Brickner, S.J.1    Barbachyn, M.R.2    Hutchinson, D.K.3    Manninen, P.R.4
  • 2
    • 84979036498 scopus 로고    scopus 로고
    • YVOX® annual appraisal of potency and spectrum (ZAAPS) programme (2014): Evolving resistance mechanisms with stable susceptibility rates
    • YVOX® annual appraisal of potency and spectrum (ZAAPS) programme (2014): evolving resistance mechanisms with stable susceptibility rates. J Antimicrob Chemother 71:1860–1865. doi:10.1093/jac/dkw052
    • (2016) J Antimicrob Chemother , vol.71 , pp. 1860-1865
    • Mendes, R.E.1    Hogan, P.A.2    Jones, R.N.3    Sader, H.S.4    Flamm, R.K.5
  • 3
    • 84902533691 scopus 로고    scopus 로고
    • Linezolid update: Stable in vitro activity following more than a decade of clinical use and summary of associated resistance mechanisms
    • Mendes RE, Deshpande LM, Jones RN (2014) Linezolid update: stable in vitro activity following more than a decade of clinical use and summary of associated resistance mechanisms. Drug Resist Updates 17:1–12. doi:10.1016/j.drup.2014.04.002
    • (2014) Drug Resist Updates , vol.17 , pp. 1-12
    • Mendes, R.E.1    Deshpande, L.M.2    Jones, R.N.3
  • 4
    • 84943328189 scopus 로고    scopus 로고
    • Tedizolid: The first once-daily oxazolidinone class antibiotic
    • Burdette SD, Trotman R (2015) Tedizolid: the first once-daily oxazolidinone class antibiotic. Clin Infect Dis 61:1315–1321. doi:10.1093/cid/civ501
    • (2015) Clin Infect Dis , vol.61 , pp. 1315-1321
    • Burdette, S.D.1    Trotman, R.2
  • 7
    • 84889648578 scopus 로고    scopus 로고
    • The discovery of rivaroxaban: Translating preclinical assessments into clinical practice
    • Kubitza D, Perzbom E, Berkowitz SD (2013) The discovery of rivaroxaban: translating preclinical assessments into clinical practice. Front Pharmacol 4:1–9. doi:10.3389/fphar. 2013.00145
    • (2013) Front Pharmacol , vol.4 , pp. 1-9
    • Kubitza, D.1    Perzbom, E.2    Berkowitz, S.D.3
  • 8
    • 0025652047 scopus 로고
    • Comparison of the monoamine oxidase inhibiting properties of two reversible and selective monoamine oxidase-A inhibitors moclobemide and toloxatone, and assessment of their effect on psychometric performance in healthy subjects
    • Berlin I, Zimmer R, Thiede H-M, Payan C, Hergueta T, Robin L, Puech AJ (1990) Comparison of the monoamine oxidase inhibiting properties of two reversible and selective monoamine oxidase-A inhibitors moclobemide and toloxatone, and assessment of their effect on psychometric performance in healthy subjects. Br J Clin Pharmacol 30:805–816. doi:10. 1111/j.1365-2125.1990.tb05445.x
    • (1990) Br J Clin Pharmacol , vol.30 , pp. 805-816
    • Berlin, I.1    Zimmer, R.2    Thiede, H.-M.3    Payan, C.4    Hergueta, T.5    Robin, L.6    Puech, A.J.7
  • 11
    • 9744232909 scopus 로고    scopus 로고
    • Time-related differences in the physical property profiles of oral drugs
    • Leeson PD, Davis AM (2004) Time-related differences in the physical property profiles of oral drugs. J Med Chem 47:6338–6348. https://doi.org/10.1021/jm049717d
    • (2004) J Med Chem , vol.47 , pp. 6338-6348
    • Leeson, P.D.1    Davis, A.M.2
  • 13
    • 84255201091 scopus 로고    scopus 로고
    • The oxazolidinones: Past, present, and future
    • Shaw KJ, Barbachyn MR (2011) The oxazolidinones: past, present, and future. Ann N Y Acad Sci 1241:48–70. doi:10.1111/j.1749-6632.2011.06330.x
    • (2011) Ann N Y Acad Sci , vol.1241 , pp. 48-70
    • Shaw, K.J.1    Barbachyn, M.R.2
  • 14
    • 84929587260 scopus 로고    scopus 로고
    • Oxazolidinone antibacterial agents
    • Dougherty TJ, Pucci MJ, Springer, New York
    • Barbachyn MR (2012) Oxazolidinone antibacterial agents. In: Dougherty TJ, Pucci MJ (eds) Antibiotic discovery and development, vol 1. Springer, New York, pp. 271–299
    • (2012) Antibiotic Discovery and Development , vol.1 , pp. 271-299
    • Barbachyn, M.R.1
  • 17
    • 51649117099 scopus 로고    scopus 로고
    • The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
    • Wilson DN, Schluenzen F, Harms JM, Starosta AL, Connell SR, Fucini P (2008) The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning. Proc Natl Acad Sci U S A 105:13339–13344. doi:10.1073/pnas.0804276105
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 13339-13344
    • Wilson, D.N.1    Schluenzen, F.2    Harms, J.M.3    Starosta, A.L.4    Connell, S.R.5    Fucini, P.6
  • 18
    • 45749089015 scopus 로고    scopus 로고
    • Crysal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit
    • Ippolito JA, Kanyo ZF, Wang D, Franceschi FJ, Moore PB, Steitz TA, Duffy EM (2008) Crysal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit. J Med Chem 51:3353–3356. doi:10.1021/jm800379d
    • (2008) J Med Chem , vol.51 , pp. 3353-3356
    • Ippolito, J.A.1    Kanyo, Z.F.2    Wang, D.3    Franceschi, F.J.4    Moore, P.B.5    Steitz, T.A.6    Duffy, E.M.7
  • 21
    • 84868035954 scopus 로고    scopus 로고
    • Selective protein synthesis by ribosomes with a drug-obstructed exit tunnel
    • Kannan K, Vázquez-Laslop N, Mankin AS (2012) Selective protein synthesis by ribosomes with a drug-obstructed exit tunnel. Cell 151:508–520. doi:10.1016/j.cell.2012.09.018
    • (2012) Cell , vol.151 , pp. 508-520
    • Kannan, K.1    Vázquez-Laslop, N.2    Mankin, A.S.3
  • 22
    • 84997830829 scopus 로고    scopus 로고
    • Binding of macrolide antibiotics leads to ribosomal selection against specific substrates based on their charge and size
    • Sothiselvam S, Neuner S, Rigger L, Klepacki D, Micura R, Vázquez-Laslop N, Mankin AS (2016) Binding of macrolide antibiotics leads to ribosomal selection against specific substrates based on their charge and size. Cell Rep 16:1789–1799. doi:10.1016/j.celrep.2016.07.018
    • (2016) Cell Rep , vol.16 , pp. 1789-1799
    • Sothiselvam, S.1    Neuner, S.2    Rigger, L.3    Klepacki, D.4    Micura, R.5    Vázquez-Laslop, N.6    Mankin, A.S.7
  • 24
    • 71249138911 scopus 로고    scopus 로고
    • Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700)
    • Locke JB, Hilgers M, Shaw KJ (2009) Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700). Antimicrob Agents Chemother 53:5265–5274. doi:10.1128/AAC.00871-09
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 5265-5274
    • Locke, J.B.1    Hilgers, M.2    Shaw, K.J.3
  • 25
    • 70449723278 scopus 로고    scopus 로고
    • Visualization of ribosomal RNA operon copy number distribution
    • Rastogi R, Wu M, DasGupta I, Fox GE (2009) Visualization of ribosomal RNA operon copy number distribution. BMC Microbiol 9:208. doi:10.1186/1471-2180-9-208
    • (2009) BMC Microbiol , vol.9 , pp. 208
    • Rastogi, R.1    Wu, M.2    Dasgupta, I.3    Fox, G.E.4
  • 26
    • 0242322580 scopus 로고    scopus 로고
    • Rapid detection and estimation by pyrosequencing of 23S rRNA genes with a single nucleotide polymorphism conferring linezolid resistance in enterococci
    • Sinclair A, Arnold C, Woodford N (2003) Rapid detection and estimation by pyrosequencing of 23S rRNA genes with a single nucleotide polymorphism conferring linezolid resistance in enterococci. Antimicrob Agents Chemother 47:3620–3622. doi:10.1128/AAC.47.11.3620-3622.2003
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 3620-3622
    • Sinclair, A.1    Arnold, C.2    Woodford, N.3
  • 28
    • 62549099077 scopus 로고    scopus 로고
    • Activity of oxazolidinone TR-700 against linezolid-susceptible and-resistant staphylococci and enterococci
    • Livermore DM, Mushtaq S, Warner M, Woodford N (2009) Activity of oxazolidinone TR-700 against linezolid-susceptible and-resistant staphylococci and enterococci. J Antimicrob Chemother 63:713–715. doi:10.1093/jac/dkp002
    • (2009) J Antimicrob Chemother , vol.63 , pp. 713-715
    • Livermore, D.M.1    Mushtaq, S.2    Warner, M.3    Woodford, N.4
  • 29
  • 30
    • 42049096982 scopus 로고    scopus 로고
    • Linezolid resistance in Staphylococcus aureus: Gene dosage effect, stability, fitness costs, and cross-resistances
    • Besier S, Ludwig A, Zander J, Brade V, Wichelhaus TA (2008) Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances. Antimicrob Agents Chemother 52:1570–1572. doi:10.1128/AAC.01098-07
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 1570-1572
    • Besier, S.1    Ludwig, A.2    Zander, J.3    Brade, V.4    Wichelhaus, T.A.5
  • 33
  • 34
    • 84856068450 scopus 로고    scopus 로고
    • Resistance to linezolid caused by modifications at its binding site on the ribosome
    • Long KS, Vester B (2012) Resistance to linezolid caused by modifications at its binding site on the ribosome. Antimicrob Agents Chemother 56:603–612. doi:10.1128/AAC.05702-11
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 603-612
    • Long, K.S.1    Vester, B.2
  • 35
    • 23744453392 scopus 로고    scopus 로고
    • A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: methylation of 23S ribosomal RNA at A2503
    • Kehrenberg C, Schwarz S, Jacobsen L, Hansen LH, Vester B (2005) A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: methylation of 23S ribosomal RNA at A2503. Mol Microbiol 57:1064–1073. doi:10.1111/j.1365-2958.2005.04754.x
    • (2005) Mol Microbiol , vol.57 , pp. 1064-1073
    • Kehrenberg, C.1    Schwarz, S.2    Jacobsen, L.3    Hansen, L.H.4    Vester, B.5
  • 36
    • 33645761164 scopus 로고    scopus 로고
    • Distribution of florfenicol resistance genes fexA and cfr among chloramphenicol-resistant staphylococcus isolates
    • Kehrenberg C, Schwarz S (2006) Distribution of florfenicol resistance genes fexA and cfr among chloramphenicol-resistant staphylococcus isolates. Antimicrob Agents Chemother 50:1156–1163. doi:10.1128/AAC.50.4.1156-1163.2006
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1156-1163
    • Kehrenberg, C.1    Schwarz, S.2
  • 37
    • 34250028674 scopus 로고    scopus 로고
    • Acquisition of a natural resistance gene renders a clinical strain of methicillin-resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid
    • Toh SM, Xiong L, Arias CA, Villegas MV, Lolans K, Quinn J, Mankin AS (2007) Acquisition of a natural resistance gene renders a clinical strain of methicillin-resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid. Mol Microbiol 64:1506–1514. doi:10.1111/j.1365-2958.2007.05744.x
    • (2007) Mol Microbiol , vol.64 , pp. 1506-1514
    • Toh, S.M.1    Xiong, L.2    Arias, C.A.3    Villegas, M.V.4    Lolans, K.5    Quinn, J.6    Mankin, A.S.7
  • 38
    • 44449125584 scopus 로고    scopus 로고
    • First report of cfr-mediated resistance to linezolid in human staphylococcal isolates recovered in the United States
    • Mendes RE, Deshpande LM, Castanheira M, DiPersio J, Saubolle MA, Jones RN (2008) First report of cfr-mediated resistance to linezolid in human staphylococcal isolates recovered in the United States. Antimicrob Agents Chemother 52:2244–2246. doi:10.1128/AAC.00231-08
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 2244-2246
    • Mendes, R.E.1    Deshpande, L.M.2    Castanheira, M.3    Dipersio, J.4    Saubolle, M.A.5    Jones, R.N.6
  • 39
    • 33745599646 scopus 로고    scopus 로고
    • The Cfr rRNA methyltransferase confers resistance to phenicols, lincosamides, oxazolidinones, pleuromutilins, and streptogramin A antibiotics
    • Long KS, Poehlsgaard J, Kehrenberg C, Schwarz S, Vester B (2006) The Cfr rRNA methyltransferase confers resistance to phenicols, lincosamides, oxazolidinones, pleuromutilins, and streptogramin A antibiotics. Antimicrob Agents Chemother 50:2500–2505. doi:10.1128/AAC.00131-06
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 2500-2505
    • Long, K.S.1    Poehlsgaard, J.2    Kehrenberg, C.3    Schwarz, S.4    Vester, B.5
  • 40
    • 84960797232 scopus 로고    scopus 로고
    • Horizontal gene transmission of the cfr gene to MRSA and Enterococcus: The role of Staphylococcus epidermidis as a reservoir and alternative pathway for the spread of linezolid resistance
    • Cafini F, Nguyen LTT, Higashide M, Roman F, Prieto J, Morikawa K (2016) Horizontal gene transmission of the cfr gene to MRSA and Enterococcus: the role of Staphylococcus epidermidis as a reservoir and alternative pathway for the spread of linezolid resistance. J Antimicrob Chemother 71:587–592. doi:10.1093/jac/dkv391
    • (2016) J Antimicrob Chemother , vol.71 , pp. 587-592
    • Cafini, F.1    Nguyen, L.T.T.2    Higashide, M.3    Roman, F.4    Prieto, J.5    Morikawa, K.6
  • 41
    • 84949115944 scopus 로고    scopus 로고
    • Update on linezolid in vitro activity through the Zyvox annual appraisal of potency and spectrum program, 2013
    • Mendes RE, Hogan PA, Streit JM, Jones RN, Flamm RK (2015) Update on linezolid in vitro activity through the Zyvox annual appraisal of potency and spectrum program, 2013. Antimicrob Agents Chemother 59:2454–2457. doi:10.1128/AAC.04784-14
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 2454-2457
    • Mendes, R.E.1    Hogan, P.A.2    Streit, J.M.3    Jones, R.N.4    Flamm, R.K.5
  • 42
    • 9744232909 scopus 로고    scopus 로고
    • Time-related differences in the physical property profiles of oral drugs
    • Leeson PD, Davis AM (2004) Time-related differences in the physical property profiles of oral drugs. J Med Chem 47:6338–6348. https://doi.org/10.1021/jm049717d
    • (2004) J Med Chem , vol.47 , pp. 6338-6348
    • Leeson, P.D.1    Davis, A.M.2
  • 44
    • 78649668302 scopus 로고    scopus 로고
    • Structure-activity relationships for linezolid-resistant Staphylococcus aureus strains possessing the cfr methyltransferase gene or ribosomal mutations
    • Locke JB, Finn J, Hilgers M, Morales G, Rahawi S, Kedar GC, Picazo JJ, Im W, Shaw KJ, Stein JL (2010) Structure-activity relationships for linezolid-resistant Staphylococcus aureus strains possessing the cfr methyltransferase gene or ribosomal mutations. Antimicrob Agents Chemother 54:5337–5343. doi:10.1128/AAC.00663-10
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 5337-5343
    • Locke, J.B.1    Finn, J.2    Hilgers, M.3    Morales, G.4    Rahawi, S.5    Kedar, G.C.6    Picazo, J.J.7    Im, W.8    Shaw, K.J.9    Stein, J.L.10
  • 45
    • 84942279482 scopus 로고    scopus 로고
    • Detection of a new cfr-like gene, cfr(B), in Enterococcus faecium isolates recovered from human specimens in the United States as part of the SENTRY antimicrobial surveillance program
    • Deshpande LM, Ashcraft DS, Kahn HP, Pankey G, Jones RN, Farrell DJ, Mendes RE (2015) Detection of a new cfr-like gene, cfr(B), in Enterococcus faecium isolates recovered from human specimens in the United States as part of the SENTRY antimicrobial surveillance program. Antimicrob Agents Chemother 59:6256–6261. doi:10.1128/AAC.01473-15
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 6256-6261
    • Deshpande, L.M.1    Ashcraft, D.S.2    Kahn, H.P.3    Pankey, G.4    Jones, R.N.5    Farrell, D.J.6    Mendes, R.E.7
  • 47
    • 84945539738 scopus 로고    scopus 로고
    • Enterococcal isolates carrying the novel oxazolidinone resistance gene optrA from hospitals in Zhejiang, Guangdong, and Henan, China, 2010–2014
    • Cai J, Wang Y, Schwarz S, Lv H, Li Y, Liao K, Yu S, Zhao K, Gu D, Wang X, Zhang R, Shen J (2015) Enterococcal isolates carrying the novel oxazolidinone resistance gene optrA from hospitals in Zhejiang, Guangdong, and Henan, China, 2010–2014. Clin Microbiol Infect 21:1095.e1–1095.e4. doi:10.1016/j.cmi.2015.08.007
    • (2015) Clin Microbiol Infect , vol.21 , pp. 1-1095
    • Cai, J.1    Wang, Y.2    Schwarz, S.3    Lv, H.4    Li, Y.5    Liao, K.6    Yu, S.7    Zhao, K.8    Gu, D.9    Wang, X.10    Zhang, R.11    Shen, J.12
  • 48
    • 9744232909 scopus 로고    scopus 로고
    • Time-related differences in the physical property profiles of oral drugs
    • Leeson PD, Davis AM (2004) Time-related differences in the physical property profiles of oral drugs. J Med Chem 47:6338–6348. https://doi.org/10.1021/jm049717d
    • (2004) J Med Chem , vol.47 , pp. 6338-6348
    • Leeson, P.D.1    Davis, A.M.2
  • 49
    • 84973316105 scopus 로고    scopus 로고
    • Co-location of the oxazolidinone resistance genes optrA and cfr on a multiresistance plasmid from Staphylococcus sciuri
    • Li D, Wang Y, Schwarz S, Cai J, Fan R, Li J, Fesler AT, Zhang R, Wu C, Shen J (2016) Co-location of the oxazolidinone resistance genes optrA and cfr on a multiresistance plasmid from Staphylococcus sciuri. J Antimicrob Chemother 71:1474–1478. doi:10.1093/jac/dkw040
    • (2016) J Antimicrob Chemother , vol.71 , pp. 1474-1478
    • Li, D.1    Wang, Y.2    Schwarz, S.3    Cai, J.4    Fan, R.5    Li, J.6    Fesler, A.T.7    Zhang, R.8    Wu, C.9    Shen, J.10
  • 51
    • 84946949457 scopus 로고    scopus 로고
    • No outbreak of vancomycin and linezolid resistance in staphylococcal pneumonia over a 10-year period
    • doi:10. 1371/journal.pone.0138895
    • Yayan J, Ghebremedhin B, Rasche K (2016) No outbreak of vancomycin and linezolid resistance in staphylococcal pneumonia over a 10-year period. PLoS One 10:1–20. doi:10. 1371/journal.pone.0138895
    • (2016) Plos One , vol.10 , pp. 1-20
    • Yayan, J.1    Ghebremedhin, B.2    Rasche, K.3
  • 52
    • 67749127546 scopus 로고    scopus 로고
    • In vitro activity of TR-700, the active ingredient of the antibacterial prodrug TR-701, a novel oxazolidinone antibacterial agent
    • Schaadt R, Sweeney D, Shinabarger D, Zurenko G (2009) In vitro activity of TR-700, the active ingredient of the antibacterial prodrug TR-701, a novel oxazolidinone antibacterial agent. Antimicrob Agents Chemother 53:3236–3239. doi:10.1128/AAC.00228-09
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 3236-3239
    • Schaadt, R.1    Sweeney, D.2    Shinabarger, D.3    Zurenko, G.4
  • 53
    • 77951234516 scopus 로고    scopus 로고
    • Comparative in vitro antimicrobial activities of torezolid (TR-700), the active moiety of a new oxazolidinone, torezolid phosphate (TR-701), determination of tentative disk diffusion interpretive criteria, and quality control ranges
    • Brown SD, Traczewski MM (2010) Comparative in vitro antimicrobial activities of torezolid (TR-700), the active moiety of a new oxazolidinone, torezolid phosphate (TR-701), determination of tentative disk diffusion interpretive criteria, and quality control ranges. Antimicrob Agents Chemother 54:2063–2069. doi:10.1128/AAC.01569-09
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 2063-2069
    • Brown, S.D.1    Traczewski, M.M.2
  • 54
    • 84865436255 scopus 로고    scopus 로고
    • Activity of tedizolid phosphate (TR-701) in murine models of infection with penicillin-resistant and penicillin-sensitive Streptococcus pneumoniae
    • Choi S, Im W, Bartizal K (2012) Activity of tedizolid phosphate (TR-701) in murine models of infection with penicillin-resistant and penicillin-sensitive Streptococcus pneumoniae. Antimicrob Agents Chemother 56:4713–4717. doi:10.1128/AAC.00346-12
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 4713-4717
    • Choi, S.1    Im, W.2    Bartizal, K.3
  • 56
    • 9744232909 scopus 로고    scopus 로고
    • Time-related differences in the physical property profiles of oral drugs
    • Leeson PD, Davis AM (2004) Time-related differences in the physical property profiles of oral drugs. J Med Chem 47:6338–6348. https://doi.org/10.1021/jm049717d
    • (2004) J Med Chem , vol.47 , pp. 6338-6348
    • Leeson, P.D.1    Davis, A.M.2
  • 57
    • 9744232909 scopus 로고    scopus 로고
    • Time-related differences in the physical property profiles of oral drugs
    • Leeson PD, Davis AM (2004) Time-related differences in the physical property profiles of oral drugs. J Med Chem 47:6338–6348. https://doi.org/10.1021/jm049717d
    • (2004) J Med Chem , vol.47 , pp. 6338-6348
    • Leeson, P.D.1    Davis, A.M.2
  • 58
    • 9744232909 scopus 로고    scopus 로고
    • Time-related differences in the physical property profiles of oral drugs
    • Leeson PD, Davis AM (2004) Time-related differences in the physical property profiles of oral drugs. J Med Chem 47:6338–6348. https://doi.org/10.1021/jm049717d
    • (2004) J Med Chem , vol.47 , pp. 6338-6348
    • Leeson, P.D.1    Davis, A.M.2
  • 59
    • 0035042226 scopus 로고    scopus 로고
    • Cardiovascular sympathomimetic amine interactions in rats treated with monoamine oxidase inhibitors and the novel oxazolidinone antibiotic linezolid
    • Humphrey SJ, Curry JT, Turman CN, Stryd RP (2001) Cardiovascular sympathomimetic amine interactions in rats treated with monoamine oxidase inhibitors and the novel oxazolidinone antibiotic linezolid. J Cardiovasc Pharmacol 37:548–563. doi:10.1097/00005344-200105000-00007
    • (2001) J Cardiovasc Pharmacol , vol.37 , pp. 548-563
    • Humphrey, S.J.1    Curry, J.T.2    Turman, C.N.3    Stryd, R.P.4
  • 60
    • 17644383350 scopus 로고    scopus 로고
    • Serotonin toxicity associated with concomitant use of linezolid
    • Bergeron L, Boulé M, Perreault S (2005) Serotonin toxicity associated with concomitant use of linezolid. Ann Pharmacother 39:956–961. doi:10.1345/aph.1E523
    • (2005) Ann Pharmacother , vol.39 , pp. 956-961
    • Bergeron, L.1    Boulé, M.2    Perreault, S.3
  • 61
    • 0242490744 scopus 로고    scopus 로고
    • Linezolid and serotonin toxicity
    • Gillman PK (2003) Linezolid and serotonin toxicity. Clin Infect Dis 37:1274–1275. doi:10. 1086/378895
    • (2003) Clin Infect Dis , vol.37 , pp. 1274-1275
    • Gillman, P.K.1
  • 62
    • 0037097653 scopus 로고    scopus 로고
    • Serotonin syndrome and linezolid
    • Wigen CL, Goetz MB (2002) Serotonin syndrome and linezolid. Clin Infect Dis 34:1651–1652. doi:10.1086/340710
    • (2002) Clin Infect Dis , vol.34 , pp. 1651-1652
    • Wigen, C.L.1    Goetz, M.B.2
  • 63
    • 0037413465 scopus 로고    scopus 로고
    • Linezolid-induced lactic acidosis
    • Apodaca AA, Rakita RM (2003) Linezolid-induced lactic acidosis. N Engl J Med 348:86–87. doi:10.1056/NEJM200301023480123
    • (2003) N Engl J Med , vol.348 , pp. 86-87
    • Apodaca, A.A.1    Rakita, R.M.2
  • 65
    • 4043151561 scopus 로고    scopus 로고
    • Peripheral neuropathy associated with prolonged use of linezolid
    • Bressler AM, Zimmer SM, Gilmore JL, Somani J (2004) Peripheral neuropathy associated with prolonged use of linezolid. Lancet Infect Dis 4:528–531. doi:10.1016/S1473-3099(04) 01109-0
    • (2004) Lancet Infect Dis , vol.4 , pp. 528-531
    • Bressler, A.M.1    Zimmer, S.M.2    Gilmore, J.L.3    Somani, J.4
  • 66
    • 14644430330 scopus 로고    scopus 로고
    • Severe sensory neuropathy associated with long-term linezolid use
    • Zivkovic SA, Lacomis D (2005) Severe sensory neuropathy associated with long-term linezolid use. Neurology 64:926–927. doi:10.1212/01.WNL.0000152883.53691.5B
    • (2005) Neurology , vol.64 , pp. 926-927
    • Zivkovic, S.A.1    Lacomis, D.2
  • 68
    • 33748535813 scopus 로고    scopus 로고
    • Effectiveness and tolerability of prolonged linezolid treatment for chronic osteomyelitis: A retrospective study
    • Senneville E, Legout L, Valette M, Yazdanpanah Y, Beltrand E, Caillaux M, Migaud H, Mouton Y (2006) Effectiveness and tolerability of prolonged linezolid treatment for chronic osteomyelitis: a retrospective study. Clin Ther 28:1155–1163. doi:10.1016/j.clinthera.2006. 08.001
    • (2006) Clin Ther , vol.28 , pp. 1155-1163
    • Senneville, E.1    Legout, L.2    Valette, M.3    Yazdanpanah, Y.4    Beltrand, E.5    Caillaux, M.6    Migaud, H.7    Mouton, Y.8
  • 69
    • 56049084881 scopus 로고    scopus 로고
    • Toxicity of extended courses of linezolid: Results of an Infectious Diseases Society of America emerging infections network survey
    • Beekmann SE, Gilbert DN, Polgreen PM (2009) Toxicity of extended courses of linezolid: results of an Infectious Diseases Society of America emerging infections network survey. Diagn Microbiol Infect Dis 62:407–410. doi:10.1016/j.diagmicrobio.2008.08.009
    • (2009) Diagn Microbiol Infect Dis , vol.62 , pp. 407-410
    • Beekmann, S.E.1    Gilbert, D.N.2    Polgreen, P.M.3
  • 70
    • 33744503144 scopus 로고    scopus 로고
    • Inhibition of mammalian mitochondrial protein synthesis by oxazolidinones
    • McKee EE, Ferguson M, Bentley AT, Marks TA (2006) Inhibition of mammalian mitochondrial protein synthesis by oxazolidinones. Antimicrob Agents Chemother 50:2042–2049. doi:10.1128/AAC.01411-05
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 2042-2049
    • McKee, E.E.1    Ferguson, M.2    Bentley, A.T.3    Marks, T.A.4
  • 71
    • 33847622511 scopus 로고    scopus 로고
    • Reversible inhibition of mitochondrial protein synthesis during linezolid-related hyperlactatemia
    • Garrabou G, Soriano A, et al (2007) Reversible inhibition of mitochondrial protein synthesis during linezolid-related hyperlactatemia. Antimicrob Agents Chemother 51:962–967. doi:10. 1128/AAC.01190-06
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 962-967
    • Garrabou, G.1    Soriano, A.2
  • 72
    • 84960824702 scopus 로고    scopus 로고
    • Toxicity to sensory neurons and Schwann cells in experimental linezolid-induced peripheral neuropathy
    • Bobylev I, Maru H, Joshi AR, Lehmann HC (2016) Toxicity to sensory neurons and Schwann cells in experimental linezolid-induced peripheral neuropathy. J Antimicrob Chemother 71:685–691. doi:10.1093/jac/dkv386
    • (2016) J Antimicrob Chemother , vol.71 , pp. 685-691
    • Bobylev, I.1    Maru, H.2    Joshi, A.R.3    Lehmann, H.C.4
  • 73
    • 84879009223 scopus 로고    scopus 로고
    • In vitro, in vivo, and clinical studies of tedizolid to assess the potential for peripheral or central monoamine oxidase interactions
    • Flanagan S, Bartizal K, Minassian SL, Fang E, Prokocimer P (2013) In vitro, in vivo, and clinical studies of tedizolid to assess the potential for peripheral or central monoamine oxidase interactions. Antimicrob Agents Chemother 57:3060–3066. doi:10.1128/AAC. 00431-13
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 3060-3066
    • Flanagan, S.1    Bartizal, K.2    Minassian, S.L.3    Fang, E.4    Prokocimer, P.5
  • 75
    • 0032960636 scopus 로고    scopus 로고
    • Activities of several novel oxazolidinones against Mycobacterium tuberculosis in a murine model
    • Cynamon MH, Klemens SP, Sharpe CA, Chase S (1999) Activities of several novel oxazolidinones against Mycobacterium tuberculosis in a murine model. Antimicrob Agents Chemother 43:1189–1191
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1189-1191
    • Cynamon, M.H.1    Klemens, S.P.2    Sharpe, C.A.3    Chase, S.4
  • 79
    • 84901289434 scopus 로고    scopus 로고
    • Population pharmacokinetic/pharmaco-dynamic analysis of the bactericidal activities of sutezolid (PNU-100480) and its major metabolite against intracellular mycobacterium tuberculosis in ex vivo whole-blood cultures of patients with pulmonary tuberculosis
    • Zhu T, Friedrich SO, Diacon A, Wallis RS (2014) Population pharmacokinetic/pharmaco-dynamic analysis of the bactericidal activities of sutezolid (PNU-100480) and its major metabolite against intracellular mycobacterium tuberculosis in ex vivo whole-blood cultures of patients with pulmonary tuberculosis. Antimicrob Agents Chemother 58:3306–3311. doi:10.1128/AAC.01920-13
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 3306-3311
    • Zhu, T.1    Friedrich, S.O.2    Diacon, A.3    Wallis, R.S.4
  • 80
    • 0035991983 scopus 로고    scopus 로고
    • In vitro evaluation of AZD2563, a novel oxazolidinone, against 603 recent staphylococcal isolates
    • Anderegg TR, Biedenbach DJ, Jones RN (2002) In vitro evaluation of AZD2563, a novel oxazolidinone, against 603 recent staphylococcal isolates. Antimicrob Agents Chemother 46:2662–2664. doi:10.1128/AAC.46.8.2662-2664.2002
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 2662-2664
    • Anderegg, T.R.1    Biedenbach, D.J.2    Jones, R.N.3
  • 82
    • 84877267006 scopus 로고    scopus 로고
    • Advances in the development of new tuberculosis drugs and treatment regimens
    • Zumla A, Nahid P, Cole ST (2013) Advances in the development of new tuberculosis drugs and treatment regimens. Nat Rev Drug Discov 12:388–404. doi:10.1038/nrd4001
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 388-404
    • Zumla, A.1    Nahid, P.2    Cole, S.T.3
  • 83
    • 84902477549 scopus 로고    scopus 로고
    • New potent oxazolidinone (MRX-I) with an improved class safety profile
    • Gordeev MF, Zhengyu YY (2014) New potent oxazolidinone (MRX-I) with an improved class safety profile. J Med Chem 57:4487–4497. doi:10.1021/jm401931eI
    • (2014) J Med Chem , vol.57 , pp. 4487-4497
    • Gordeev, M.F.1    Zhengyu, Y.Y.2
  • 84
    • 9744232909 scopus 로고    scopus 로고
    • Time-related differences in the physical property profiles of oral drugs
    • Leeson PD, Davis AM (2004) Time-related differences in the physical property profiles of oral drugs. J Med Chem 47:6338–6348. https://doi.org/10.1021/jm049717d
    • (2004) J Med Chem , vol.47 , pp. 6338-6348
    • Leeson, P.D.1    Davis, A.M.2
  • 86
    • 84940387006 scopus 로고    scopus 로고
    • Metabolism of MRX-I, a novel antibacterial oxazolidinone, in humans: The oxidative ring opening of 2,3-dihydropyridin-4-one catalyzed by non-P450 enzymes
    • Meng J, Zhong D, Li L, Yuan Z, Yuan H, Xie C, Zhou J, Li C, Gordeev MF, Liu J, Chen X (2015) Metabolism of MRX-I, a novel antibacterial oxazolidinone, in humans: the oxidative ring opening of 2,3-dihydropyridin-4-one catalyzed by non-P450 enzymes. Drug Metab Dipos 43:646–659. doi:10.1124/dmd.114.061747
    • (2015) Drug Metab Dipos , vol.43 , pp. 646-659
    • Meng, J.1    Zhong, D.2    Li, L.3    Yuan, Z.4    Yuan, H.5    Xie, C.6    Zhou, J.7    Li, C.8    Gordeev, M.F.9    Liu, J.10    Chen, X.11
  • 87
    • 42949106448 scopus 로고    scopus 로고
    • In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens
    • Lawrence L, Danese P, DeVito J, Franceschi F, Sutcliffe J (2008) In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. Antimicrob Agents Chemother 52:1653–1662. doi:10.1128/AAC.01383-07
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 1653-1662
    • Lawrence, L.1    Danese, P.2    Devito, J.3    Franceschi, F.4    Sutcliffe, J.5
  • 90
    • 0037447946 scopus 로고    scopus 로고
    • Design, synthesis and biological evaluation of oxazolidinone-quinolone hybrids
    • Hubschwerlen C, Specklin J-L, Sigwalt C, Schroeder S, Locher HH (2003) Design, synthesis and biological evaluation of oxazolidinone-quinolone hybrids. Bioorg Med Chem 11:2313–2319. doi:10.1016/S0968-0896(03)00083-X
    • (2003) Bioorg Med Chem , vol.11 , pp. 2313-2319
    • Hubschwerlen, C.1    Specklin, J.-L.2    Sigwalt, C.3    Schroeder, S.4    Locher, H.H.5
  • 92
    • 84942850284 scopus 로고    scopus 로고
    • A multicenter, double-blind, randomized, phase 2 study evaluating the novel antibiotic, cadazolid, in patients with Clostridium difficile infection
    • Louie T, Nord CE, Talbot GH, Wilcox M, Gerding DM, Buitrago M, Kracker H, Charef P, Comely OA (2015) A multicenter, double-blind, randomized, phase 2 study evaluating the novel antibiotic, cadazolid, in patients with Clostridium difficile infection. Antimicrob Agents Chemother 59:6266–6273. doi:10.1128/AAC.00504-15
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 6266-6273
    • Louie, T.1    Nord, C.E.2    Talbot, G.H.3    Wilcox, M.4    Gerding, D.M.5    Buitrago, M.6    Kracker, H.7    Charef, P.8    Comely, O.A.9
  • 101
    • 0025219010 scopus 로고
    • Cir and Fiu proteins in the outer membrane of Escherichia coli catalyze transport of monomeric catechols: Study with 1-lactam antibiotics containing catechol and analogous groups
    • Nikaido H, Rosenberg EY (1990) Cir and Fiu proteins in the outer membrane of Escherichia coli catalyze transport of monomeric catechols: study with 1-lactam antibiotics containing catechol and analogous groups. J Bacteriol 172:1361–1367
    • (1990) J Bacteriol , vol.172 , pp. 1361-1367
    • Nikaido, H.1    Rosenberg, E.Y.2
  • 102
    • 84947264564 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of novel 5-(Hydroxamic acid) methyl oxazolidinone derivatives
    • Phillips OA, D’Silva R, Bahta TO, Sharaf LH, Udo EE, Benov L, Walters DE (2015) Synthesis and biological evaluation of novel 5-(hydroxamic acid) methyl oxazolidinone derivatives. Eur J Med Chem 106:120–131. doi:10.1016/j.ejmech.2015.10.025
    • (2015) Eur J Med Chem , vol.106 , pp. 120-131
    • Phillips, O.A.1    D’Silva, R.2    Bahta, T.O.3    Sharaf, L.H.4    Udo, E.E.5    Benov, L.6    Walters, D.E.7
  • 103
    • 84942502131 scopus 로고    scopus 로고
    • Novel oxazolidinone antibacterial analogues with a substituted ligustrazine C-ring unit
    • Chen Y, Ruan Z-X, Wang F, Huangfu D-S, Sun P-H, Lin J, Chen W-M (2015) Novel oxazolidinone antibacterial analogues with a substituted ligustrazine C-ring unit. Chem Biol Drug Des 86:682–690. doi:10.1111/cbdd.12537
    • (2015) Chem Biol Drug Des , vol.86 , pp. 682-690
    • Chen, Y.1    Ruan, Z.-X.2    Wang, F.3    Huangfu, D.-S.4    Sun, P.-H.5    Lin, J.6    Chen, W.-M.7
  • 104
    • 85006186498 scopus 로고    scopus 로고
    • Progress against Escherichia coli with the oxazolidinone class of antibacterials: Test case for a general approach to improving whole-cell Gram-negative activity
    • Takrouri K, Cooper HD, Spaulding A, Zucchi P, Koleva B, Cleary DC, Tear W, Beuning PJ, Hirsch EB, Aggen JB (2016) Progress against Escherichia coli with the oxazolidinone class of antibacterials: test case for a general approach to improving whole-cell Gram-negative activity. ACS Infect Dis 2:405–426. doi:10.1021/acsinfecdis.6b00003
    • (2016) ACS Infect Dis , vol.2 , pp. 405-426
    • Takrouri, K.1    Cooper, H.D.2    Spaulding, A.3    Zucchi, P.4    Koleva, B.5    Cleary, D.C.6    Tear, W.7    Beuning, P.J.8    Hirsch, E.B.9    Aggen, J.B.10
  • 105
    • 84947596423 scopus 로고    scopus 로고
    • A convenient synthesis of the antibacterial agent linezolid
    • McCarthy JR (2015) A convenient synthesis of the antibacterial agent linezolid. Tetrahedron Lett 56:6846–6847. doi:10.1016/j.tetlet.2015.10.082
    • (2015) Tetrahedron Lett , vol.56 , pp. 6846-6847
    • McCarthy, J.R.1
  • 106
    • 84960225679 scopus 로고    scopus 로고
    • Copper catalyzed assembly of N-aryloxazolidinones: Synthesis of linezolid, tedizolid and rivaroxaban
    • Mahy W, Leitch JA, Frost CG (2016) Copper catalyzed assembly of N-aryloxazolidinones: synthesis of linezolid, tedizolid and rivaroxaban. Eur J Org Chem 2016:1305–1313. doi:10. 1002/ejoc.201600033
    • (2016) Eur J Org Chem , vol.2016 , pp. 1305-1313
    • Mahy, W.1    Leitch, J.A.2    Frost, C.G.3


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