Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition

Chemistry and Biology

Volumn 17, Issue 5, 2010, Pages 504-514

  Starosta, Agata L ^a   Karpenko, Viktoriya V ^b   Shishkina, Anna V ^b   Mikolajka, Aleksandra ^a   Sumbatyan, Natalia V ^b   Schluenzen, Frank ^c   Korshunova, Galina A ^b   Bogdanov, Alexey A ^b   Wilson, Daniel N ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c DESY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOACYL TRANSFER RNA; ANTIINFECTIVE AGENT; MACROLIDE; PEPTIDE; PROTEIN SYNTHESIS INHIBITOR; TRNA, PEPTIDYL; TRNA, PEPTIDYL-; TYLOSIN;

ARTICLE; CHEMISTRY; DRUG EFFECT; METABOLISM; PROTEIN BINDING; PROTEIN SYNTHESIS; PROTEIN TERTIARY STRUCTURE; RIBOSOME;

ANTI-BACTERIAL AGENTS; MACROLIDES; PEPTIDES; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, TERTIARY; PROTEIN SYNTHESIS INHIBITORS; RIBOSOMES; RNA, TRANSFER, AMINO ACYL; TYLOSIN;

EID: 77954185197     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2010.04.008     Document Type: Article

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