Reversible inhibition of mitochondrial protein synthesis during linezolid-related hyperlactatemia

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 3, 2007, Pages 962-967

  Garrabou, Glòria ^a   Soriano, Alejandro ^a   López, Sònia ^a   Guallar, Jordi P ^b   Giralt, Marta ^b   Villarroya, Francesc ^b   Martínez, Jose A ^a   Casademont, Jordi ^a   Cardellach, Francesc ^a   Mensa, Josep ^a   Miró, Òscar ^a  

^a HOSPITAL CLÍNIC   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; ISOENZYME; LACTIC ACID; LINEZOLID; MESSENGER RNA; MITOCHONDRIAL DNA; MITOCHONDRIAL ENZYME;

ADULT; AGED; ANEMIA; ARTICLE; BACTERIAL INFECTION; CLINICAL ARTICLE; CONTROLLED STUDY; DNA CONTENT; DRUG WITHDRAWAL; ENZYME ACTIVITY; ENZYME SUBUNIT; FEMALE; GASTROINTESTINAL SYMPTOM; GENETIC TRANSCRIPTION; HOMEOSTASIS; HUMAN; HYPERLACTATEMIA; MALE; MEASUREMENT; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL TOXICITY; MITOCHONDRION; OXIDATION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; RNA TRANSLATION; THROMBOCYTOPENIA;

ACETAMIDES; ADULT; AGED; ANTI-BACTERIAL AGENTS; DNA; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX IV; FEMALE; HUMANS; LACTATES; LONGITUDINAL STUDIES; MALE; MEMBRANE POTENTIALS; MITOCHONDRIA; OXAZOLIDINONES; OXIDATION-REDUCTION; PROTEIN SYNTHESIS INHIBITORS; RNA;

EID: 33847622511     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.01190-06     Document Type: Article

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