Mycobactericidal activity of sutezolid (PNU-100480) in sputum (EBA) and blood (WBA) of patients with pulmonary tuberculosis

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Wallis, Robert S ^a,f   Dawson, Rodney ^b   Friedrich, Sven O ^c   Venter, Amour ^d   Paige, Darcy ^a   Zhu, Tong ^a   Silvia, Annette ^a   Gobey, Jason ^a   Ellery, Craig ^a   Zhang, Yao ^a   Eisenach, Kathleen ^e   Miller, Paul ^a,g   Diacon, Andreas H ^c  

^a PFIZER INC   (United States)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c UNIVERSITY OF STELLENBOSCH   (South Africa)

^d STELLENBOSCH UNIVERSITY   (South Africa)

^e UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^f AURUM INSTITUTE   (South Africa)

^g ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ETHAMBUTOL PLUS ISONIAZID PLUS PYRAZINAMIDE PLUS RIFAMPICIN; SUTEZOLID; ALANINE AMINOTRANSFERASE; OXAZOLIDINONE DERIVATIVE; PNU-100480;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ARTICLE; BACTERIAL COUNT; BACTERIAL LOAD; BACTERICIDAL ACTIVITY; BACTERIUM CULTURE; BLOOD; BLOOD CULTURE; CONTROLLED STUDY; DRUG SAFETY; DRUG TOLERABILITY; EX VIVO STUDY; FEMALE; HUMAN; INOCULATION; LIQUID CULTURE; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; QT INTERVAL; RANDOMIZED CONTROLLED TRIAL; SPUTUM; TREATMENT DURATION; ANIMAL; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MOUSE; SERUM BACTERICIDAL ACTIVITY; TUBERCULOSIS, PULMONARY;

ADULT; ALANINE TRANSAMINASE; ANIMALS; BLOOD BACTERICIDAL ACTIVITY; COLONY COUNT, MICROBIAL; FEMALE; HUMANS; MALE; MICE; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; OXAZOLIDINONES; SPUTUM; TUBERCULOSIS, PULMONARY;

EID: 84899637134     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094462     Document Type: Article

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