Toxicity of extended courses of linezolid: results of an Infectious Diseases Society of America Emerging Infections Network survey

Diagnostic Microbiology and Infectious Disease

Volumn 62, Issue 4, 2008, Pages 407-410

  Beekmann, Susan E ^a   Gilbert, David N ^b   Polgreen, Philip M ^a  

^a UNIVERSITY OF IOWA   (United States)

^b PROVIDENCE PORTLAND MEDICAL CENTER   (United States)

Author keywords

Antimicrobial toxicity; Inhibition of mitochondrial protein synthesis; Lactic acidosis; Linezolid

Indexed keywords

LINEZOLID; SEROTONIN UPTAKE INHIBITOR;

ANEMIA; ANXIETY DISORDER; ARTICLE; CLINICAL PRACTICE; CONFUSION; DRUG ERUPTION; DRUG WITHDRAWAL; HEALTH SURVEY; HOSPITAL PHYSICIAN; HUMAN; INFECTION; LABORATORY TEST; LACTIC ACIDOSIS; MEDICAL SOCIETY; MOUTH PAIN; MYOSITIS; NAUSEA AND VOMITING; NEUTROPENIA; OPTIC NERVE DISEASE; PATIENT MONITORING; PERIPHERAL NEUROPATHY; PRESCRIPTION; PRIORITY JOURNAL; SEROTONIN SYNDROME; SIDE EFFECT; THROMBOCYTOPENIA; TREATMENT RESPONSE;

ACETAMIDES; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; COMMUNICABLE DISEASES, EMERGING; DATA COLLECTION; DRUG ADMINISTRATION SCHEDULE; HUMANS; OXAZOLIDINONES; PHYSICIAN'S PRACTICE PATTERNS; SOCIETIES, MEDICAL; UNITED STATES;

EID: 56049084881     PISSN: 07328893     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2008.08.009     Document Type: Article

References (11)

1. Bernard L., Stern R., Lew D., and Hoffmeyer P. Serotonin syndrome after concomitant treatment with linezolid and citalopram. Clin. Infect. Dis. 36 (2003) 1197
2. Bishop E., Melvani S., Howden B.P., Charles P.G.P., and Grayson M.L. Good clinical outcomes but high rates of adverse reactions during linezolid therapy for serious infections: a proposed protocol for monitoring therapy in complex patients. Antimicrob. Agents Chemother. 50 (2006) 1599-1602
3. Das P.K., Warkentin D.I., Hewko R., and Forrest D.L. Serotonin syndrome after concomitant treatment with linezolid and meperidine. Clin. Infect. Dis. 46 (2008) 264-265
4. Ferry T., Ponceau B., Simon M., Issartel B., Petiot P., Boibieux A., Biron F., Chidiac C., and Peyramond D. Possibly linezolid-induced peripheral and central neurotoxicity: report of four cases. Infection 33 (2005) 151-154
5. Garrabou G., Soriano A., Lopez S., Guallar J.P., Girald M., Villarroya F., Martinez J.A., Casademont J., Cardellach F., Mensa J., and Miro O. Reversible inhibition of mitochondrial protein synthesis during linezolid-related hyperlactatemia. Antimicrob. Agents Chemother. 51 (2007) 962-967
6. Lawrence K.R., Adra M., and Gillman P.K. Serotonin toxicity associated with the use of linezolid: a review of postmarketing data. Clin. Infect. Dis. 42 (2006) 1578-1583
7. McKee E.E., Ferguson M., Bentley A.T., and Marks T.A. Inhibition of mammalian mitochondrial protein synthesis by oxazolidinones. Antimicrob. Agents. Chemother. 50 (2006) 2042-2049
8. Narita M., Tsuji B.T., and Yu V.L. Linezolid-associated peripheral and optic neuropathy, lactic acidosis, and serotonin syndrome. Pharmacother 27 (2007) 1189-1197
9. Soriano A., Miro O., and Mensa J. Mitochondrial toxicity associated with linezolid. N. Engl. J. Med. 353 (2005) 2305-2306
10. Taylor J.J., Wilson J.W., and Estes L.L. Linezolid and serotonergic drug interactions: a retrospective survey. Clin. Infect. Dis. 43 (2006) 180-187
11. von der Lippe B., Sandven P., and Brubakk O. Efficacy and safety of linezolid in multidrug resistant tuberculosis (MDR-TB)-a report of ten cases. J. Infect. 52 (2006) 92-96