Gene dosage and linezolid resistance in Enterococcus faecium and Enterococcus faecalis

Antimicrobial Agents and Chemotherapy

Volumn 46, Issue 10, 2002, Pages 3334-3336

  Marshall, S H ^a   Donskey, C J ^a   Hutton Thomas, R ^a   Salata, R A ^a   Rice, L B ^a  

^a LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; BACTERIAL RNA; LINEZOLID; RIBOSOME RNA; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; GENE DOSAGE; GENE EXPRESSION; GENE MUTATION; GENE STRUCTURE; GENETIC ANALYSIS; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

ACETAMIDES; DRUG RESISTANCE, BACTERIAL; ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; GENE DOSAGE; GENES, RRNA; HUMANS; MUTATION; OXAZOLIDINONES; POLYMERASE CHAIN REACTION; RNA, RIBOSOMAL, 23S;

EID: 0036783696     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.46.10.3334-3336.2002     Document Type: Article

References (9)

1. Genetic linkage and cotransfer of a novel vanB-containing transposon (Tn5382) and a low-affinity penicillin-binding protein 5 gene in a clinical vancomycin-resistant Enterococcus faecium isolate
2. A polyclonal outbreak of predominantly VanB vancomycin-resistant enterococci in northeast Ohio
3. Infections due to vancomycin-resistant Enterococcus faecium resistant to linezolid
4. Resistance mutations in 23S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center
5. Resistance to linezolid: Characterization of mutations in rRNA and comparison of their occurrences in vancomycin-resistant enterococci
6. Mechanism of action of oxazolidinones: Effects of linezolid and eperezolid on translation reactions
7. Diversity of domain V of 23S rRNA gene sequence in different Enterococcus species
8. Linezolid resistance in a clinical isolate of Staphylococcus aureus