An evolved oxazolidinone with selective potency against Mycobacterium tuberculosis and gram positive bacteria

Bioorganic and Medicinal Chemistry Letters

Volumn 26, Issue 15, 2016, Pages 3572-3576

  Kaushik, Amit ^a   Heuer, Abigail M ^b   Bell, Drew T ^a   Culhane, Jeffrey C ^b   Ebner, David C ^b   Parrish, Nicole ^a   Ippoliti, J Thomas ^b   Lamichhane, Gyanu ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ST THOMAS   (United States)

Author keywords

Antimicrobials; E. faecalis; Mycobacterium tuberculosis; Oxazolidinone; Staphylococcus aureus

Indexed keywords

BIAPENEM; DORIPENEM; FROPENEM; OXAZOLIDINONE DERIVATIVE; TEBIPENEM; ANTIINFECTIVE AGENT;

ARTICLE; BACTERICIDAL ACTIVITY; DRUG POTENCY; DRUG SELECTIVITY; ENTEROCOCCUS FAECALIS; GRAM POSITIVE BACTERIUM; GROWTH INHIBITION; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STAPHYLOCOCCUS AUREUS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GRAM NEGATIVE BACTERIUM; GROWTH, DEVELOPMENT AND AGING; MICROBIAL SENSITIVITY TEST; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTI-BACTERIAL AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; OXAZOLIDINONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84977596084     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2016.06.019     Document Type: Article

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