Binding of Macrolide Antibiotics Leads to Ribosomal Selection against Specific Substrates Based on Their Charge and Size

Cell Reports

Volumn 16, Issue 7, 2016, Pages 1789-1799

  Sothiselvam, Shanmugapriya ^a   Neuner, Sandro ^b   Rigger, Lukas ^b   Klepacki, Dorota ^a   Micura, Ronald ^b   Vázquez Laslop, Nora ^a   Mankin, Alexander S ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; ERYTHROMYCIN; MACROLIDE; MESSENGER RNA; PEPTIDE; PSEUDOMONIC ACID; SOLITHROMYCIN; TRANSFER RNA; AMINOACYL TRANSFER RNA; PEPTIDYLTRANSFERASE; PROTEIN SYNTHESIS INHIBITOR;

ARTICLE; CATALYSIS; CODON; DRUG BINDING; IN VITRO STUDY; MUTATION; PRIORITY JOURNAL; RIBOSOME; RNA SEQUENCE; RNA STRUCTURE; BINDING SITE; CHEMISTRY; DRUG EFFECTS; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; NUCLEOTIDE SEQUENCE; PROTEIN MOTIF; PROTEIN SYNTHESIS; STATIC ELECTRICITY;

AMINO ACID MOTIFS; BASE SEQUENCE; BINDING SITES; ESCHERICHIA COLI; MACROLIDES; PEPTIDYL TRANSFERASES; PROTEIN BIOSYNTHESIS; PROTEIN SYNTHESIS INHIBITORS; RIBOSOMES; RNA, MESSENGER; RNA, TRANSFER, AMINO ACYL; STATIC ELECTRICITY; SUBSTRATE SPECIFICITY;

EID: 84997830829     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.07.018     Document Type: Article

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