ApoE facilitates the microglial response to amyloid plaque pathology

Journal of Experimental Medicine

Volumn 215, Issue 4, 2018, Pages 1047-1058

  Ulrich, Jason D ^a   Ulland, Tyler K ^a   Mahan, Thomas E ^a   Nyström, Sofie ^b   Peter Nilsson, K ^b   Song, Wilbur M ^a   Zhou, Yingyue ^a   Reinartz, Mariska ^a,c   Choi, Seulah ^a   Jiang, Hong ^a   Stewart, Floy R ^a   Anderson, Elise ^a   Wang, Yaming ^a,d   Colonna, Marco ^a   Holtzman, David M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LINKÖPING UNIVERSITY   (Sweden)

^c RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^d ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; BCL2A1B PROTEIN; C5AR1 PROTEIN; CCL6 PROTEIN; CD68 ANTIGEN; CST7 PROTEIN; DECTIN 1; FLUORESCENT DYE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IFI27L2A PROTEIN; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; ITGAX PROTEIN; LAT2 PROTEIN; LUMINESCENT AGENT; LUMINESCENT CONJUGATED OLIGOTHIOPHENE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 1; PEPTIDES AND PROTEINS; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; TSC22D3 PROTEIN; TUMOR NECROSIS FACTOR; TYROBP PROTEIN; UNCLASSIFIED DRUG; WDFY1 PROTEIN; AMYLOID PRECURSOR PROTEIN;

AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DYSTROPHY; FLUORESCENCE IMAGING; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GLIOSIS; INNATE IMMUNITY; MICROGLIA; MOLECULAR PATHOLOGY; MORPHOTYPE; MOUSE; NEURITE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; ALZHEIMER DISEASE; ANIMAL; BRAIN; DISEASE MODEL; HUMAN; IMMUNOLOGY; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; APOLIPOPROTEINS E; BRAIN; DISEASE MODELS, ANIMAL; HUMANS; IMMUNITY, INNATE; MICE; MICE, TRANSGENIC; MICROGLIA; PLAQUE, AMYLOID;

EID: 85044831295     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20171265     Document Type: Article

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