-
1
-
-
34248673126
-
Isolation of murine microglial cells for RNA analysis or flow cytometry
-
Cardona, A. E., Huang, D., Sasse, M. E. & Ransohoff, R. M. Isolation of murine microglial cells for RNA analysis or flow cytometry. Nat. Protoc. 1, 1947-1951 (2006).
-
(2006)
Nat. Protoc
, vol.1
, pp. 1947-1951
-
-
Cardona, A.E.1
Huang, D.2
Sasse, M.E.3
Ransohoff, R.M.4
-
2
-
-
0025900245
-
Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system
-
Sedgwick, J. D. et al. Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system. Proc. Natl Acad. Sci. USA 88, 7438-7442 (1991).
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 7438-7442
-
-
Sedgwick, J.D.1
-
3
-
-
84860322835
-
Genomic analysis of reactive astrogliosis
-
Zamanian, J. L. et al. Genomic analysis of reactive astrogliosis. J. Neurosci. 32, 6391-6410 (2012).
-
(2012)
J. Neurosci
, vol.32
, pp. 6391-6410
-
-
Zamanian, J.L.1
-
4
-
-
84862163088
-
Trehalose-enhanced isolation of neuronal sub-types from adult mouse brain
-
Saxena, A. et al. Trehalose-enhanced isolation of neuronal sub-types from adult mouse brain. BioTechniques 52, 381-385 (2012).
-
(2012)
BioTechniques
, vol.52
, pp. 381-385
-
-
Saxena, A.1
-
5
-
-
84910047887
-
Dissecting gene expression at the blood-brain barrier
-
Huntley, M. A., Bien-Ly, N., Daneman, R. & Watts, R. J. Dissecting gene expression at the blood-brain barrier. Front. Neurosci. 8, 355 (2014).
-
(2014)
Front. Neurosci
, vol.8
, pp. 355
-
-
Huntley, M.A.1
Bien-Ly, N.2
Daneman, R.3
Watts, R.J.4
-
6
-
-
84907457155
-
Characterization of oligodendroglial populations in mouse demyelinating disease using flow cytometry: Clues for MS pathogenesis
-
Robinson, A. P., Rodgers, J. M., Goings, G. E. & Miller, S. D. Characterization of oligodendroglial populations in mouse demyelinating disease using flow cytometry: clues for MS pathogenesis. PLoS ONE 9, e107649 (2014).
-
(2014)
PLoS ONE
, vol.9
-
-
Robinson, A.P.1
Rodgers, J.M.2
Goings, G.E.3
Miller, S.D.4
-
7
-
-
84893745524
-
Identification of a unique TGF-beta-dependent molecular and functional signature in microglia
-
Butovsky, O. et al. Identification of a unique TGF-beta-dependent molecular and functional signature in microglia. Nat. Neurosci. 17, 131-143 (2014).
-
(2014)
Nat. Neurosci
, vol.17
, pp. 131-143
-
-
Butovsky, O.1
-
8
-
-
84888324248
-
The microglial sensome revealed by direct RNA sequencing
-
Hickman, S. E. et al. The microglial sensome revealed by direct RNA sequencing. Nature neuroscience 16, 1896-1905 (2013).
-
(2013)
Nature Neuroscience
, vol.16
, pp. 1896-1905
-
-
Hickman, S.E.1
-
9
-
-
84906901689
-
An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex
-
Zhang, Y. et al. An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. J. Neurosci. 34, 11929-11947 (2014).
-
(2014)
J. Neurosci
, vol.34
, pp. 11929-11947
-
-
Zhang, Y.1
-
10
-
-
80755168022
-
CX3CR1 deficiency leads to impairment of hippocampal cognitive function and synaptic plasticity
-
Rogers, J. T. et al. CX3CR1 deficiency leads to impairment of hippocampal cognitive function and synaptic plasticity. J. Neurosci. 31, 16241-16250 (2011).
-
(2011)
J. Neurosci
, vol.31
, pp. 16241-16250
-
-
Rogers, J.T.1
-
11
-
-
77957316313
-
CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models
-
Lee, S. et al. CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models. Am. J. Pathol. 177, 2549-2562 (2010).
-
(2010)
Am. J. Pathol
, vol.177
, pp. 2549-2562
-
-
Lee, S.1
-
12
-
-
81555204354
-
FACS purification of immunolabeled cell types from adult rat brain
-
Guez-Barber, D. et al. FACS purification of immunolabeled cell types from adult rat brain. J. Neurosci. Methods 203, 10-18 (2012).
-
(2012)
J. Neurosci. Methods
, vol.203
, pp. 10-18
-
-
Guez-Barber, D.1
-
13
-
-
43049143907
-
Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration
-
Chen-Plotkin, A. S. et al. Variations in the progranulin gene affect global gene expression in frontotemporal lobar degeneration. Hum. Mol. Genet. 17, 1349-1362 (2008).
-
(2008)
Hum. Mol. Genet
, vol.17
, pp. 1349-1362
-
-
Chen-Plotkin, A.S.1
-
14
-
-
0141707862
-
PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation
-
Richards, J. G. et al. PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation. J. Neurosci. 23, 8989-9003 (2003).
-
(2003)
J. Neurosci
, vol.23
, pp. 8989-9003
-
-
Richards, J.G.1
-
15
-
-
84888399981
-
Deletion of galectin-3 exacerbates microglial activation and accelerates disease progression and demise in a SOD1(G93A) mouse model of amyotrophic lateral sclerosis
-
Lerman, B. J. et al. Deletion of galectin-3 exacerbates microglial activation and accelerates disease progression and demise in a SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Brain Behav. 2, 563-575 (2012).
-
(2012)
Brain Behav
, vol.2
, pp. 563-575
-
-
Lerman, B.J.1
-
16
-
-
77949477815
-
Sporadic ALS has compartment-specific aberrant exon splicing and altered cell-matrix adhesion biology
-
Rabin, S. J. et al. Sporadic ALS has compartment-specific aberrant exon splicing and altered cell-matrix adhesion biology. Hum. Mol. Genet. 19, 313-328 (2010).
-
(2010)
Hum. Mol. Genet
, vol.19
, pp. 313-328
-
-
Rabin, S.J.1
-
17
-
-
84856715245
-
Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model
-
Kamphuis, W., Orre, M., Kooijman, L., Dahmen, M. & Hol, E. M. Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model. Glia 60, 615-629 (2012).
-
(2012)
Glia
, vol.60
, pp. 615-629
-
-
Kamphuis, W.1
Orre, M.2
Kooijman, L.3
Dahmen, M.4
Hol, E.M.5
-
18
-
-
84907385189
-
Proliferation in the Alzheimer hippocampus is due to microglia, not astroglia, and occurs at sites of amyloid deposition
-
Marlatt, M. W. et al. Proliferation in the Alzheimer hippocampus is due to microglia, not astroglia, and occurs at sites of amyloid deposition. Neural Plast. 2014, 693851 (2014).
-
(2014)
Neural Plast
, vol.2014
-
-
Marlatt, M.W.1
-
19
-
-
70449529633
-
The blood-brain barrier and immune function and dysfunction
-
Banks, W. A. & Erickson, M. A. The blood-brain barrier and immune function and dysfunction. Neurobiol. Dis. 37, 26-32 (2010).
-
(2010)
Neurobiol. Dis
, vol.37
, pp. 26-32
-
-
Banks, W.A.1
Erickson, M.A.2
-
20
-
-
84888859097
-
Endotoxin-induced experimental systemic inflammation in humans: A model to disentangle immune-to-brain communication
-
Schedlowski, M., Engler, H. & Grigoleit, J. S. Endotoxin-induced experimental systemic inflammation in humans: a model to disentangle immune-to-brain communication. Brain Behav. Immun. 35, 1-8 (2014).
-
(2014)
Brain Behav. Immun
, vol.35
, pp. 1-8
-
-
Schedlowski, M.1
Engler, H.2
Grigoleit, J.S.3
-
21
-
-
0037320253
-
Molecular insights on the cerebral innate immune system
-
Rivest, S. Molecular insights on the cerebral innate immune system. Brain Behav. Immun. 17, 13-19 (2003).
-
(2003)
Brain Behav. Immun
, vol.17
, pp. 13-19
-
-
Rivest, S.1
-
22
-
-
80054993342
-
Spatio-temporal transcriptome of the human brain
-
Kang, H. J. et al. Spatio-temporal transcriptome of the human brain. Nature 478, 483-489 (2011).
-
(2011)
Nature
, vol.478
, pp. 483-489
-
-
Kang, H.J.1
-
23
-
-
84880802569
-
A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
-
Chiu, I. M. et al. A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model. Cell Rep. 4, 385-401 (2013).
-
(2013)
Cell Rep
, vol.4
, pp. 385-401
-
-
Chiu, I.M.1
-
24
-
-
77952581425
-
Aberrant RNA processing events in neurological disorders
-
Anthony, K. & Gallo, J. M. Aberrant RNA processing events in neurological disorders. Brain Res. 1338, 67-77 (2010).
-
(2010)
Brain Res
, vol.1338
, pp. 67-77
-
-
Anthony, K.1
Gallo, J.M.2
-
26
-
-
84865527768
-
Detecting differential usage of exons from RNA-seq data
-
Anders, S., Reyes, A. & Huber, W. Detecting differential usage of exons from RNA-seq data. Genome Res. 22, 2008-2017 (2012).
-
(2012)
Genome Res
, vol.22
, pp. 2008-2017
-
-
Anders, S.1
Reyes, A.2
Huber, W.3
-
27
-
-
35748967921
-
A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis
-
Chan, C. W. et al. A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis. Biochem. J. 407, 355-362 (2007).
-
(2007)
Biochem. J
, vol.407
, pp. 355-362
-
-
Chan, C.W.1
-
28
-
-
55949104665
-
TNF signaling inhibition in the CNS: Implications for normal brain function and neurodegenerative disease
-
McCoy, M. K. & Tansey, M. G. TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease. J. Neuroinflammation 5, 45 (2008).
-
(2008)
J. Neuroinflammation
, vol.5
, pp. 45
-
-
McCoy, M.K.1
Tansey, M.G.2
-
29
-
-
77952291438
-
Tumor necrosis factor-alpha mediated signaling in neuronal homeostasis and dysfunction
-
Park, K. M. & Bowers, W. J. Tumor necrosis factor-alpha mediated signaling in neuronal homeostasis and dysfunction. Cell. Signal. 22, 977-983 (2010).
-
(2010)
Cell. Signal
, vol.22
, pp. 977-983
-
-
Park, K.M.1
Bowers, W.J.2
-
30
-
-
79953181649
-
Lipoprotein lipase is a novel amyloid beta (Abeta)-binding protein that promotes glycosaminoglycan-dependent cellular uptake of Abeta in astrocytes
-
Nishitsuji, K., Hosono, T., Uchimura, K. & Michikawa, M. Lipoprotein lipase is a novel amyloid beta (Abeta)-binding protein that promotes glycosaminoglycan-dependent cellular uptake of Abeta in astrocytes. J. Biol. Chem. 286, 6393-6401 (2011).
-
(2011)
J. Biol. Chem
, vol.286
, pp. 6393-6401
-
-
Nishitsuji, K.1
Hosono, T.2
Uchimura, K.3
Michikawa, M.4
-
31
-
-
84885171213
-
Activated cyclin-dependent kinase 5 promotes microglial phagocytosis of fibrillar beta-amyloid by up-regulating lipoprotein lipase expression
-
Ma, Y. et al. Activated cyclin-dependent kinase 5 promotes microglial phagocytosis of fibrillar beta-amyloid by up-regulating lipoprotein lipase expression. Mol. Cell. Proteomics 12, 2833-2844 (2013).
-
(2013)
Mol. Cell. Proteomics
, vol.12
, pp. 2833-2844
-
-
Ma, Y.1
-
32
-
-
79960935129
-
LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking
-
Ranganathan, S. et al. LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking. J. Neurosci. 31, 10836-10846 (2011).
-
(2011)
J. Neurosci
, vol.31
, pp. 10836-10846
-
-
Ranganathan, S.1
-
33
-
-
84858423000
-
Reducing human apolipoprotein e levels attenuates age-dependent Abeta accumulation in mutant human amyloid precursor protein transgenic mice
-
Bien-Ly, N., Gillespie, A. K., Walker, D., Yoon, S. Y. & Huang, Y. Reducing human apolipoprotein E levels attenuates age-dependent Abeta accumulation in mutant human amyloid precursor protein transgenic mice. J. Neurosci. 32, 4803-4811 (2012).
-
(2012)
J. Neurosci
, vol.32
, pp. 4803-4811
-
-
Bien-Ly, N.1
Gillespie, A.K.2
Walker, D.3
Yoon, S.Y.4
Huang, Y.5
-
34
-
-
0033787295
-
Two splice variants of the hypoxia-inducible factor HIF-1alpha as potential dimerization partners of ARNT2 in neurons
-
Drutel, G. et al. Two splice variants of the hypoxia-inducible factor HIF-1alpha as potential dimerization partners of ARNT2 in neurons. Eur. J. Neurosci. 12, 3701-3708 (2000).
-
(2000)
Eur. J. Neurosci
, vol.12
, pp. 3701-3708
-
-
Drutel, G.1
-
35
-
-
9644269066
-
Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation
-
Sato, F. et al. Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation. Interaction with BMAL1. Eur. J. Biochem. 271, 4409-4419 (2004).
-
(2004)
Interaction with BMAL1. Eur. J. Biochem
, vol.271
, pp. 4409-4419
-
-
Sato, F.1
-
36
-
-
0025304816
-
Tumor necrosis factor-alpha production by astrocytes. Induction by lipopolysaccharide
-
Chung, I. Y. & Benveniste, E. N. Tumor necrosis factor-alpha production by astrocytes. Induction by lipopolysaccharide, IFN-gamma, and IL-1 beta. J. Immunol. 144, 2999-3007 (1990).
-
(1990)
IFN-gamma, and IL-1 Beta. J. Immunol
, vol.144
, pp. 2999-3007
-
-
Chung, I.Y.1
Benveniste, E.N.2
-
37
-
-
0001139213
-
Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus
-
Lieberman, A. P., Pitha, P. M., Shin, H. S. & Shin, M. L. Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus. Proc. Natl Acad. Sci. USA 86, 6348-6352 (1989).
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 6348-6352
-
-
Lieberman, A.P.1
Pitha, P.M.2
Shin, H.S.3
Shin, M.L.4
-
38
-
-
0023281068
-
Production of cytotoxic factor for oligodendrocytes by stimulated astrocytes
-
Robbins, D. S. et al. Production of cytotoxic factor for oligodendrocytes by stimulated astrocytes. J. Immunol. 139, 2593-2597 (1987).
-
(1987)
J. Immunol
, vol.139
, pp. 2593-2597
-
-
Robbins, D.S.1
-
39
-
-
84856739147
-
Microglia are required for astroglial Toll-like receptor 4 response and for optimal TLR2 and TLR3 response
-
Holm, T. H., Draeby, D. & Owens, T. Microglia are required for astroglial Toll-like receptor 4 response and for optimal TLR2 and TLR3 response. Glia 60, 630-638 (2012).
-
(2012)
Glia
, vol.60
, pp. 630-638
-
-
Holm, T.H.1
Draeby, D.2
Owens, T.3
-
40
-
-
84944881561
-
Lack of widespread BBB Disruption in Alzheimer's Disease Models: Focus on Therapeutic Antibodies
-
Bien-Ly, N. et al. Lack of widespread BBB Disruption in Alzheimer's Disease Models: Focus on Therapeutic Antibodies. Neuron 88, 289-297 (2015).
-
(2015)
Neuron
, vol.88
, pp. 289-297
-
-
Bien-Ly, N.1
-
42
-
-
77951820899
-
Fast and SNP-tolerant detection of complex variants and splicing in short reads
-
Wu, T. D. & Nacu, S. Fast and SNP-tolerant detection of complex variants and splicing in short reads. Bioinformatics 26, 873-881 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 873-881
-
-
Wu, T.D.1
Nacu, S.2
-
43
-
-
84924629414
-
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
-
Love, M. I., Huber, W. & Anders, S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 15, 550 (2014).
-
(2014)
Genome Biol
, vol.15
, pp. 550
-
-
Love, M.I.1
Huber, W.2
Anders, S.3
-
44
-
-
84865022311
-
Primer3-new capabilities and interfaces
-
Untergasser, A. et al. Primer3-new capabilities and interfaces. Nucleic Acids Res. 40, e115 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, pp. e115
-
-
Untergasser, A.1
-
45
-
-
0142121516
-
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
-
Irizarry, R. A. et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4, 249-264 (2003).
-
(2003)
Biostatistics
, vol.4
, pp. 249-264
-
-
Irizarry, R.A.1
-
46
-
-
77953095629
-
Independent filtering increases detection power for high-throughput experiments
-
Bourgon, R., Gentleman, R. & Huber, W. Independent filtering increases detection power for high-throughput experiments. Proc. Natl Acad. Sci. USA 107, 9546-9551 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 9546-9551
-
-
Bourgon, R.1
Gentleman, R.2
Huber, W.3
-
47
-
-
33645756545
-
-
(eds Carey, V., Gentleman, R., Dudoit, S., Irizarry, R. & Huber, W.), Springer
-
Smyth, G. K. in Bioinformatics and Compuational Biology Solutions using R and Bioconductor (Statistics for Biology and Health) (eds Carey, V., Gentleman, R., Dudoit, S., Irizarry, R. & Huber, W.) 397-420 (Springer, 2005).
-
(2005)
Bioinformatics and Compuational Biology Solutions Using R and Bioconductor (Statistics for Biology and Health)
, pp. 397-420
-
-
Smyth, G.K.1
-
48
-
-
84891804649
-
Database resources of the National Center for Biotechnology Information
-
NCBI-Coordinators
-
NCBI-Coordinators. Database resources of the National Center for Biotechnology Information. Nucleic acids Res. 42, D7-17 (2014).
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D7-17
-
-
|