Apolipoprotein E is a ligand for triggering receptor expressed on myeloid cells 2 (TREM2)

Journal of Biological Chemistry

Volumn 290, Issue 43, 2015, Pages 26043-26050

  Atagi, Yuka ^a   Liu, Chia Chen ^a   Painter, Meghan M ^a   Chen, Xiao Fen ^a   Verbeeck, Christophe ^a   Zheng, Honghua ^a   Li, Xia ^a   Rademakers, Rosa ^a   Kang, Silvia S ^a   Xu, Huaxi ^a   Younkin, Steven ^a   Das, Pritam ^a   Fryer, John D ^a,b   Bu, Guojun ^a,b  

^a MAYO CLINIC   (United States)

^b XIAMEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; ASSAYS; BINS; CELLS; CYTOLOGY; IMMUNOLOGY; LIGANDS; LIPOPROTEINS; PROTEINS;

ALZHEIMER DISEASE; APOLIPOPROTEIN E (APOE); BIOCHEMICAL ASSAY; CENTRAL NERVOUS SYSTEMS; FRONTOTEMPORAL DEMENTIAS; HIGH AFFINITY BINDING; NEUROINFLAMMATION; NEUROLOGICAL DISORDERS;

NEURODEGENERATIVE DISEASES;

APOLIPOPROTEIN A1; APOLIPOPROTEIN E; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; IMMUNOGLOBULIN RECEPTOR; LIGAND; MEMBRANE PROTEIN; PROTEIN BINDING; TREM2 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; MICROGLIA; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ALZHEIMER DISEASE; ANIMAL; APOPTOSIS; GENETICS; HEK293 CELL LINE; HUMAN; KNOCKOUT MOUSE; METABOLISM; NERVE CELL;

ALZHEIMER DISEASE; ANIMALS; APOLIPOPROTEINS E; APOPTOSIS; HEK293 CELLS; HUMANS; LIGANDS; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; NEURONS; PHAGOCYTOSIS; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC;

EID: 84944937240     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.679043     Document Type: Article

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