Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition

Journal of Neuroinflammation

Volumn 11, Issue , 2014, Pages

  Rodriguez, Gustavo A ^a   Tai, Leon M ^b   LaDu, Mary J ^b   Rebeck, G W ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Alzheimer's disease; APOE4; A 1 42; Microglia; MOAB2; Neuroinflammation

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E4; INTERLEUKIN 1BETA; AMYLOID PRECURSOR PROTEIN; PRESENILIN 1; PSEN1 PROTEIN, HUMAN;

AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOLIPOPROTEIN E GENE; ARTICLE; ASTROCYTE; BRAIN CORTEX; CELL ACTIVATION; DYSTROPHY; GENOTYPE; IMMUNOHISTOCHEMISTRY; MICROGLIA; MOUSE; MOUSE MODEL; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; SUBICULUM; TRANSGENIC MOUSE; ALZHEIMER DISEASE; ANIMAL; CONFOCAL MICROSCOPY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MUTATION; PATHOLOGY;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; APOLIPOPROTEIN E4; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1BETA; MICE; MICE, TRANSGENIC; MICROGLIA; MICROSCOPY, CONFOCAL; MUTATION; PLAQUE, AMYLOID; PRESENILIN-1;

EID: 84902759627     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-11-111     Document Type: Article

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