The structural organization of substrate loading in iterative polyketide synthases

Nature Chemical Biology

Volumn 14, Issue 5, 2018, Pages 474-479

  Herbst, Dominik A ^a   Huitt Roehl, Callie R ^b   Jakob, Roman P ^a   Kravetz, Jacob M ^b   Storm, Philip A ^b   Alley, Jamie R ^b   Townsend, Craig A ^b   Maier, Timm ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEIN; ALANINE; ARGININE; GLUTAMIC ACID; HISTIDINE; POLYKETIDE SYNTHASE; 2-BROMOPROPIONIC ACID; CROSS LINKING REAGENT; PANTETHEINE; PROPIONIC ACID DERIVATIVE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; ENZYME STRUCTURE; ENZYME SUBSTRATE; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN CROSS LINKING; ASCOMYCETES; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ESCHERICHIA COLI; METABOLISM; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN MULTIMERIZATION; X RAY CRYSTALLOGRAPHY;

ACYL CARRIER PROTEIN; ASCOMYCOTA; CATALYTIC DOMAIN; CROSS-LINKING REAGENTS; CRYOELECTRON MICROSCOPY; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; PANTETHEINE; PHOSPHORYLATION; POLYKETIDE SYNTHASES; PROPIONATES; PROTEIN CONFORMATION; PROTEIN DOMAINS; PROTEIN MULTIMERIZATION; SUBSTRATE SPECIFICITY;

EID: 85044766221     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/s41589-018-0026-3     Document Type: Article

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