Structure of the Human Fatty Acid Synthase KS-MAT Didomain as a Framework for Inhibitor Design

Journal of Molecular Biology

Volumn 397, Issue 2, 2010, Pages 508-519

  Pappenberger, Günter ^a   Benz, Jörg ^a   Gsell, Bernard ^a   Hennig, Michael ^a   Ruf, Armin ^a   Stihle, Martine ^a   Thoma, Ralf ^a   Rudolph, Markus G ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

fatty acid synthesis; metabolic disease; synthase; transferase; X ray crystallography

Indexed keywords

ACYLTRANSFERASE; BETA KETOACYL SYNTHASE; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE INHIBITOR; MALONYLTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME STRUCTURE; HUMAN; PLASTICITY; PRIORITY JOURNAL; STRUCTURAL HOMOLOGY; STRUCTURE ANALYSIS;

BACTERIA (MICROORGANISMS); MAMMALIA; SUS;

EID: 77349098976     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.01.066     Document Type: Article

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