메뉴 건너뛰기




Volumn 103, Issue 3, 2018, Pages 382-394

Extracellular vesicles in the hematopoietic microenvironment

Author keywords

[No Author keywords available]

Indexed keywords

ADP RIBOSYL CYCLASE/CYCLIC ADP RIBOSE HYDROLASE 1; ALPHA3 INTEGRIN; CD19 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; CD5 ANTIGEN; CD63 ANTIGEN; CD82 ANTIGEN; COMPLEMENT COMPONENT C3D RECEPTOR; DECAY ACCELERATING FACTOR; DICKKOPF 1 PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ESCRT PROTEIN; GELATINASE B; HERMES ANTIGEN; HLA A ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 8; L SELECTIN; PLATELET ENDOTHELIAL CELL ADHESION MOLECULE 1; PROTEIN JAGGED 1; PROTEIN MDM2; PROTEIN P53; SCATTER FACTOR RECEPTOR; SOMATOMEDIN C; STEM CELL FACTOR RECEPTOR; STROMAL CELL DERIVED FACTOR 1; UNINDEXED DRUG;

EID: 85042775243     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2017.183335     Document Type: Review
Times cited : (72)

References (103)
  • 1
    • 84892610064 scopus 로고    scopus 로고
    • The bone marrow niche for haematopoietic stem cells
    • Morrison SJ, Scadden DT. The bone marrow niche for haematopoietic stem cells. Nature. 2014;505(7483):327–334.
    • (2014) Nature , vol.505 , Issue.7483 , pp. 327-334
    • Morrison, S.J.1    Scadden, D.T.2
  • 2
    • 84855885803 scopus 로고    scopus 로고
    • Cell cycle regulation in hematopoietic stem cells
    • Pietras EM, Warr MR, Passegué E. Cell cycle regulation in hematopoietic stem cells. J Cell Biol. 2011;195(5):709–720.
    • (2011) J Cell Biol , vol.195 , Issue.5 , pp. 709-720
    • Pietras, E.M.1    Warr, M.R.2    Passegué, E.3
  • 3
    • 84924272696 scopus 로고    scopus 로고
    • Normal and leukemic stem cell niches: Insights and therapeutic opportunities
    • Schepers K, Campbell TB, Passegué E. Normal and leukemic stem cell niches: insights and therapeutic opportunities. Cell Stem Cell. 2015;16(3):254–267.
    • (2015) Cell Stem Cell , vol.16 , Issue.3 , pp. 254-267
    • Schepers, K.1    Campbell, T.B.2    Passegué, E.3
  • 4
    • 84930933095 scopus 로고    scopus 로고
    • TGF-β signaling in the control of hematopoietic stem cells
    • Blank U, Karlsson S. TGF-β signaling in the control of hematopoietic stem cells. Blood. 2015;125(23):3542–3550.
    • (2015) Blood , vol.125 , Issue.23 , pp. 3542-3550
    • Blank, U.1    Karlsson, S.2
  • 5
    • 33747613351 scopus 로고    scopus 로고
    • Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells
    • Yamazaki S, Iwama A, Takayanagi S-I, et al. Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells. EMBO. 2006;25(15):3515–3523.
    • (2006) EMBO , vol.25 , Issue.15 , pp. 3515-3523
    • Yamazaki, S.1    Iwama, A.2    Takayanagi, S.-I.3
  • 6
    • 39749178390 scopus 로고    scopus 로고
    • Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo
    • Fleming HE, Janzen V, Celso Lo C, et al. Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell. 2008;2(3):274–283.
    • (2008) Cell Stem Cell , vol.2 , Issue.3 , pp. 274-283
    • Fleming, H.E.1    Janzen, V.2    Celso Lo, C.3
  • 7
    • 44649190505 scopus 로고    scopus 로고
    • The PI-3kinase pathway in hematopoietic stem cells and leukemia-initiating cells: A mechanistic difference between normal and cancer stem cells
    • Yilmaz OH, Morrison SJ. The PI-3kinase pathway in hematopoietic stem cells and leukemia-initiating cells: a mechanistic difference between normal and cancer stem cells. Blood Cells Mol Dis. 2008;41(1):73–76.
    • (2008) Blood Cells Mol Dis , vol.41 , Issue.1 , pp. 73-76
    • Yilmaz, O.H.1    Morrison, S.J.2
  • 8
    • 57849108116 scopus 로고    scopus 로고
    • Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells
    • Colmone A, Amorim M, Pontier AL, Wang S, Jablonski E, Sipkins DA. Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells. Science. 2008;322(5909):1861–1865.
    • (2008) Science , vol.322 , Issue.5909 , pp. 1861-1865
    • Colmone, A.1    Amorim, M.2    Pontier, A.L.3    Wang, S.4    Jablonski, E.5    Sipkins, D.A.6
  • 9
    • 33645314949 scopus 로고    scopus 로고
    • Exosomes biological significance: a concise review
    • Johnstone RM. Exosomes biological significance: a concise review. Blood Cells Mol Dis. 2006;36(2):315–321.
    • (2006) Blood Cells Mol Dis , vol.36 , Issue.2 , pp. 315-321
    • Johnstone, R.M.1
  • 10
    • 85015317590 scopus 로고    scopus 로고
    • Adipose-derived circulating miRNAs regulate gene expression in other tissues
    • Thomou T, Mori MA, Dreyfuss JM, et al. Adipose-derived circulating miRNAs regulate gene expression in other tissues. Nature. 2017;542(7642):450–455.
    • (2017) Nature , vol.542 , Issue.7642 , pp. 450-455
    • Thomou, T.1    Mori, M.A.2    Dreyfuss, J.M.3
  • 11
    • 79955070767 scopus 로고    scopus 로고
    • Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells
    • Mittelbrunn M, Gutiérrez-Vázquez C, Villarroya-Beltri C, et al. Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Nat Commun. 2017;2:282.
    • (2017) Nat Commun , vol.2 , pp. 282
    • Mittelbrunn, M.1    Gutiérrez-Vázquez, C.2    Villarroya-Beltri, C.3
  • 12
    • 85014619748 scopus 로고    scopus 로고
    • Biological properties of extracellular vesicles and their physiological functions
    • Yáñez-Mó M, Siljander PR-M, Andreu Z, et al. Biological properties of extracellular vesicles and their physiological functions. J Extracell Vesicles. 2015;4(0):27066.
    • (2015) J Extracell Vesicles , vol.4 , pp. 27066
    • Yáñez-Mó, M.1    Siljander, P.R.-M.2    Andreu, Z.3
  • 13
    • 84988845025 scopus 로고    scopus 로고
    • AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB
    • Hornick NI, Doron B, Abdelhamed S, et al. AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB. Sci Signal. 2016;9(444):ra88.
    • (2016) Sci Signal. , vol.9 , Issue.444
    • Hornick, N.I.1    Doron, B.2    Abdelhamed, S.3
  • 14
    • 85035016569 scopus 로고    scopus 로고
    • Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion
    • [Epub ahead of print]
    • Kumar B, Garcia M, Weng L, et al. Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion. Leukemia. 2017 Aug 17. [Epub ahead of print]
    • (2017) Leukemia
    • Kumar, B.1    Garcia, M.2    Weng, L.3
  • 15
    • 0014082202 scopus 로고
    • The nature and significance of platelet products in human plasma
    • Wolf P. The nature and significance of platelet products in human plasma. Br J Haematol. 1967;13(3):269–288.
    • (1967) Br J Haematol , vol.13 , Issue.3 , pp. 269-288
    • Wolf, P.1
  • 16
    • 0020956787 scopus 로고
    • Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: Selective externalization of the receptor
    • Pan BT, Johnstone RM. Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. Cell. 1983;33(3):967–978.
    • (1983) Cell , vol.33 , Issue.3 , pp. 967-978
    • Pan, B.T.1    Johnstone, R.M.2
  • 17
    • 84995752697 scopus 로고    scopus 로고
    • Mesenchymal stromal cell-derived extracellular vesicles promote myeloid-biased multi-potent hematopoietic progenitor expansion via Toll-like receptor engagement
    • Goloviznina NA, Verghese SC, Yoon YM, Taratula O, Marks DL, Kurre P. Mesenchymal stromal cell-derived extracellular vesicles promote myeloid-biased multi-potent hematopoietic progenitor expansion via Toll-like receptor engagement. J Biol Chem. 2016;291(47): 24607–24617.
    • (2016) J Biol Chem , vol.291 , Issue.47 , pp. 24607-24617
    • Goloviznina, N.A.1    Verghese, S.C.2    Yoon, Y.M.3    Taratula, O.4    Marks, D.L.5    Kurre, P.6
  • 18
    • 84955207383 scopus 로고    scopus 로고
    • Tissue factor-positive tumor microvesicles activate platelets and enhance thrombosis in mice
    • Geddings JE, Hisada Y, Boulaftali Y, et al. Tissue factor-positive tumor microvesicles activate platelets and enhance thrombosis in mice. J Thromb Haemost. 2016;14(1):153–166.
    • (2016) J Thromb Haemost , vol.14 , Issue.1 , pp. 153-166
    • Geddings, J.E.1    Hisada, Y.2    Boulaftali, Y.3
  • 19
    • 62649095692 scopus 로고    scopus 로고
    • Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR
    • Al-Nedawi K, Meehan B, Kerbel RS, Allison AC, Rak J. Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR. Proc Natl Acad Sci USA. 2009;106(10):3794–3799.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.10 , pp. 3794-3799
    • Al-Nedawi, K.1    Meehan, B.2    Kerbel, R.S.3    Allison, A.C.4    Rak, J.5
  • 20
    • 84947723880 scopus 로고    scopus 로고
    • Tumour exosome integrins determine organotropic metastasis
    • Hoshino A, Costa-Silva B, Shen T-L, et al. Tumour exosome integrins determine organotropic metastasis. Nature. 2015;527(7578):329–335.
    • (2015) Nature , vol.527 , Issue.7578 , pp. 329-335
    • Hoshino, A.1    Costa-Silva, B.2    Shen, T.-L.3
  • 21
    • 84875846330 scopus 로고    scopus 로고
    • BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression
    • Roccaro AM, Sacco A, Maiso P, et al. BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. J Clin Invest. 2013;123(4):1542–1555.
    • (2013) J Clin Invest , vol.123 , Issue.4 , pp. 1542-1555
    • Roccaro, A.M.1    Sacco, A.2    Maiso, P.3
  • 22
    • 84959386845 scopus 로고    scopus 로고
    • Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
    • Kowal J, Arras G, Colombo M, et al. Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes. Proc Natl Acad Sci USA. 2016;113(8):E968–977.
    • (2016) Proc Natl Acad Sci USA , vol.113 , Issue.8 , pp. E968-E977
    • Kowal, J.1    Arras, G.2    Colombo, M.3
  • 23
    • 85002514611 scopus 로고    scopus 로고
    • Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis
    • Gu H, Chen C, Hao X, et al. Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis. J Clin Invest. 2016;126(12):4537-4553.
    • (2016) J Clin Invest , vol.126 , Issue.12 , pp. 4537-4553
    • Gu, H.1    Chen, C.2    Hao, X.3
  • 24
    • 79953136097 scopus 로고    scopus 로고
    • Rab27a and Rab27b control different steps of the exosome secretion pathway
    • Ostrowski M, Carmo NB, Krumeich S, et al. Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol. 2010;12(1):19–30
    • (2010) Nat Cell Biol , vol.12 , Issue.1 , pp. 19-30
    • Ostrowski, M.1    Carmo, N.B.2    Krumeich, S.3
  • 25
    • 84959513695 scopus 로고    scopus 로고
    • Cells release subpopulations of exosomes with distinct molecular and biological properties
    • Willms E, Johansson HJ, Mäger I, et al. Cells release subpopulations of exosomes with distinct molecular and biological properties. Sci Rep. 2016;6(1):22519.
    • (2016) Sci Rep , vol.6 , Issue.1 , pp. 22519
    • Willms, E.1    Johansson, H.J.2    Mäger, I.3
  • 26
    • 85020648971 scopus 로고    scopus 로고
    • Single exosome study reveals subpopulations distributed among cell lines with variability related to membrane content
    • Smith ZJ, Lee C, Rojalin T, et al. Single exosome study reveals subpopulations distributed among cell lines with variability related to membrane content. J Extracell Vesicles. 2015;4:28533.
    • (2015) J Extracell Vesicles , vol.4 , pp. 28533
    • Smith, Z.J.1    Lee, C.2    Rojalin, T.3
  • 27
    • 84874377202 scopus 로고    scopus 로고
    • Extracellular vesicles: Exosomes, microvesicles, and friends
    • Raposo G, Stoorvogel W. Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol. 2013;200(4):373–383.
    • (2013) J Cell Biol , vol.200 , Issue.4 , pp. 373-383
    • Raposo, G.1    Stoorvogel, W.2
  • 28
    • 84872469459 scopus 로고    scopus 로고
    • Antibacterial effect of microvesicles released from human neutrophilic granulocytes
    • Timár CI, Lőrincz ÁM, Csépányi-Kömi R, et al. Antibacterial effect of microvesicles released from human neutrophilic granulocytes. Blood. 2013;121(3):510–518.
    • (2013) Blood , vol.121 , Issue.3 , pp. 510-518
    • Timár, C.I.1    Lőrincz, Á.M.2    Csépányi-Kömi, R.3
  • 29
    • 85015685520 scopus 로고    scopus 로고
    • Acute lymphoblastic leukaemia cells produce large extracellular vesicles containing organelles and an active cytoskeleton
    • Johnson SM, Dempsey C, Parker C, Mironov A, Bradley H, Saha V. Acute lymphoblastic leukaemia cells produce large extracellular vesicles containing organelles and an active cytoskeleton. J Extracell Vesicles. 2017;6(1):e1294339.
    • (2017) J Extracell Vesicles , vol.6 , Issue.1
    • Johnson, S.M.1    Dempsey, C.2    Parker, C.3    Mironov, A.4    Bradley, H.5    Saha, V.6
  • 30
    • 84868208632 scopus 로고    scopus 로고
    • Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease
    • Di Vizio D, Morello M, Dudley AC, et al. Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease. Am J Pathol. 2012;181(5):1573–1584.
    • (2012) Am J Pathol , vol.181 , Issue.5 , pp. 1573-1584
    • Di Vizio, D.1    Morello, M.2    Dudley, A.C.3
  • 31
    • 39749182234 scopus 로고    scopus 로고
    • Apoptosis: Controlled demolition at the cellular level
    • Taylor RC, Cullen SP, Martin SJ. Apoptosis: controlled demolition at the cellular level. Nat Rev Mol Cell Biol. 2008;9(3):231–241.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.3 , pp. 231-241
    • Taylor, R.C.1    Cullen, S.P.2    Martin, S.J.3
  • 32
    • 0033152288 scopus 로고    scopus 로고
    • Horizontal transfer of DNA by the uptake of apoptotic bodies
    • Holmgren L, Szeles A, Rajnavölgyi E, et al. Horizontal transfer of DNA by the uptake of apoptotic bodies. Blood. 1999;93(11):3956–3963.
    • (1999) Blood , vol.93 , Issue.11 , pp. 3956-3963
    • Holmgren, L.1    Szeles, A.2    Rajnavölgyi, E.3
  • 33
    • 57149087260 scopus 로고    scopus 로고
    • Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes
    • Hakulinen J, Sankkila L, Sugiyama N, Lehti K, Keski-Oja J. Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes. J Cell Biochem. 2008;105(5):1211–1218.
    • (2008) J Cell Biochem , vol.105 , Issue.5 , pp. 1211-1218
    • Hakulinen, J.1    Sankkila, L.2    Sugiyama, N.3    Lehti, K.4    Keski-Oja, J.5
  • 34
    • 85003945007 scopus 로고    scopus 로고
    • Extracellular vesicles in ccncer: Cell-to-cell mediators of metastasis
    • Becker A, Thakur BK, Weiss JM, Kim HS, Peinado H, Lyden D. Extracellular vesicles in ccncer: cell-to-cell mediators of metastasis. Cancer Cell. 2016;30(6):836–848.
    • (2016) Cancer Cell , vol.30 , Issue.6 , pp. 836-848
    • Becker, A.1    Thakur, B.K.2    Weiss, J.M.3    Kim, H.S.4    Peinado, H.5    Lyden, D.6
  • 35
    • 84876729225 scopus 로고    scopus 로고
    • Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection
    • Takahashi Y, Nishikawa M, Shinotsuka H, et al. Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection. J Biotechnol. 2013;165(2):77–84.
    • (2013) J Biotechnol , vol.165 , Issue.2 , pp. 77-84
    • Takahashi, Y.1    Nishikawa, M.2    Shinotsuka, H.3
  • 36
    • 85013654823 scopus 로고    scopus 로고
    • Routes and mechanisms of extracellular vesicle uptake
    • Mulcahy LA, Pink RC, Carter DR. Routes and mechanisms of extracellular vesicle uptake. J Extracell Vesicles. 2014;3(1):24641.
    • (2014) J Extracell Vesicles , vol.3 , Issue.1 , pp. 24641
    • Mulcahy, L.A.1    Pink, R.C.2    Carter, D.R.3
  • 37
    • 84886387008 scopus 로고    scopus 로고
    • Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity
    • Christianson HC, Svensson KJ, van Kuppevelt TH, Li J-P, Belting M. Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity. Proc Natl Acad Sci USA. 2013;110(43):17380–17385.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.43 , pp. 17380-17385
    • Christianson, H.C.1    Svensson, K.J.2    van Kuppevelt, T.H.3    Li, J.-P.4    Belting, M.5
  • 38
    • 79953081976 scopus 로고    scopus 로고
    • Interaction and uptake of exosomes by ovarian cancer cells
    • Escrevente C, Keller S, Altevogt P, Costa J. Interaction and uptake of exosomes by ovarian cancer cells. BMC Cancer. 2011;11(1):108.
    • (2011) BMC Cancer , vol.11 , Issue.1 , pp. 108
    • Escrevente, C.1    Keller, S.2    Altevogt, P.3    Costa, J.4
  • 39
    • 84879046970 scopus 로고    scopus 로고
    • Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1
    • Svensson KJ, Christianson HC, Wittrup A, et al. Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1. J Biol Chem. 2013;288(24):17713–17724.
    • (2013) J Biol Chem , vol.288 , Issue.24 , pp. 17713-17724
    • Svensson, K.J.1    Christianson, H.C.2    Wittrup, A.3
  • 40
    • 77449102731 scopus 로고    scopus 로고
    • Galectin-5 is bound onto the surface of rat reticulocyte exosomes and modulates vesicle uptake by macrophages
    • Barrès C, Blanc L, Bette-Bobillo P, et al. Galectin-5 is bound onto the surface of rat reticulocyte exosomes and modulates vesicle uptake by macrophages. Blood. 2010;115(3):696–705.
    • (2010) Blood , vol.115 , Issue.3 , pp. 696-705
    • Barrès, C.1    Blanc, L.2    Bette-Bobillo, P.3
  • 41
    • 57749169272 scopus 로고    scopus 로고
    • Tetraspanins: Push and pull in suppressing and promoting metastasis
    • Zöller M. Tetraspanins: push and pull in suppressing and promoting metastasis. Nature. 2009;9(1):40–55.
    • (2009) Nature , vol.9 , Issue.1 , pp. 40-55
    • Zöller, M.1
  • 43
    • 28444441957 scopus 로고    scopus 로고
    • Tetraspanin functions and associated microdomains
    • Hemler ME. Tetraspanin functions and associated microdomains. Nat Rev Mol Cell Biol. 2005;6(10):801–811.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , Issue.10 , pp. 801-811
    • Hemler, M.E.1
  • 44
    • 0037097563 scopus 로고    scopus 로고
    • C-kit associated with the transmembrane 4 superfamily proteins constitutes a functionally distinct subunit in human hematopoietic progenitors
    • Anzai N, Lee Y, Youn B-S, et al. C-kit associated with the transmembrane 4 superfamily proteins constitutes a functionally distinct subunit in human hematopoietic progenitors. Blood. 2002;99(12):4413–4421.
    • (2002) Blood , vol.99 , Issue.12 , pp. 4413-4421
    • Anzai, N.1    Lee, Y.2    Youn, B.-S.3
  • 45
    • 84926456125 scopus 로고    scopus 로고
    • Tetraspanins as therapeutic targets in hematological malignancy: A concise review
    • Beckwith KA, Byrd JC, Muthusamy N. Tetraspanins as therapeutic targets in hematological malignancy: a concise review. Front Physiol. 2015;6:91.
    • (2015) Front Physiol , vol.6 , pp. 91
    • Beckwith, K.A.1    Byrd, J.C.2    Muthusamy, N.3
  • 46
    • 84969262605 scopus 로고    scopus 로고
    • Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER
    • Heusermann W, Hean J, Trojer D, et al. Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER. J Cell Biol. 2016;213(2):173–184.
    • (2016) J Cell Biol , vol.213 , Issue.2 , pp. 173-184
    • Heusermann, W.1    Hean, J.2    Trojer, D.3
  • 47
    • 84876927914 scopus 로고    scopus 로고
    • Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
    • Kucharzewska P, Christianson HC, Welch JE, et al. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc Natl Acad Sci USA. 2013;110(18):7312–7317.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.18 , pp. 7312-7317
    • Kucharzewska, P.1    Christianson, H.C.2    Welch, J.E.3
  • 48
    • 84969963343 scopus 로고    scopus 로고
    • Mesenchymal stromal cell-derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells
    • Wen S, Dooner M, Cheng Y, et al. Mesenchymal stromal cell-derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells. Leukemia. 2016;30(11):2221–2231.
    • (2016) Leukemia , vol.30 , Issue.11 , pp. 2221-2231
    • Wen, S.1    Dooner, M.2    Cheng, Y.3
  • 50
    • 84888986034 scopus 로고    scopus 로고
    • Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells
    • Tadokoro H, Umezu T, Ohyashiki K, Hirano T, Ohyashiki JH. Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells. J Biol Chem. 2013;288(48):34343–34351.
    • (2013) J Biol Chem , vol.288 , Issue.48 , pp. 34343-34351
    • Tadokoro, H.1    Umezu, T.2    Ohyashiki, K.3    Hirano, T.4    Ohyashiki, J.H.5
  • 51
    • 84951569690 scopus 로고    scopus 로고
    • Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes
    • Huan J, Hornick NI, Goloviznina NA, et al. Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes. Leukemia. 2015;29(12): 2285–2295.
    • (2015) Leukemia , vol.29 , Issue.12 , pp. 2285-2295
    • Huan, J.1    Hornick, N.I.2    Goloviznina, N.A.3
  • 52
    • 84862128486 scopus 로고    scopus 로고
    • MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular cell adhesion molecule 1
    • Salvucci O, Jiang K, Gasperini P, et al. MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular cell adhesion molecule 1. Haematologica. 2012;97(6):818–826.
    • (2012) Haematologica , vol.97 , Issue.6 , pp. 818-826
    • Salvucci, O.1    Jiang, K.2    Gasperini, P.3
  • 53
    • 85015663550 scopus 로고    scopus 로고
    • Angiogenic mechanisms of human CD34(+) stem cell exosomes in the repair of ischemic hindlimb
    • Mathiyalagan P, Liang Y, Kim D, et al. Angiogenic mechanisms of human CD34(+) stem cell exosomes in the repair of ischemic hindlimb. Circ Res. 2017;120(9):1466–1476.
    • (2017) Circ Res , vol.120 , Issue.9 , pp. 1466-1476
    • Mathiyalagan, P.1    Liang, Y.2    Kim, D.3
  • 54
    • 84969884453 scopus 로고    scopus 로고
    • Activated Stat5 trafficking via endothelial cell-derived extracellular vesicles controls IL-3 pro-angiogenic paracrine action
    • Lombardo G, Dentelli P, Togliatto G, et al. Activated Stat5 trafficking via endothelial cell-derived extracellular vesicles controls IL-3 pro-angiogenic paracrine action. Sci Rep. 2016;6(1):25689.
    • (2016) Sci Rep , vol.6 , Issue.1 , pp. 25689
    • Lombardo, G.1    Dentelli, P.2    Togliatto, G.3
  • 55
    • 84977644852 scopus 로고    scopus 로고
    • Secreted microvesicular miR-31 inhibits osteogenic differentiation of mesenchymal stem cells
    • Weilner S, Schraml E, Wieser M, et al. Secreted microvesicular miR-31 inhibits osteogenic differentiation of mesenchymal stem cells. Aging Cell. 2016;15(4):744–754.
    • (2016) Aging Cell , vol.15 , Issue.4 , pp. 744-754
    • Weilner, S.1    Schraml, E.2    Wieser, M.3
  • 57
    • 85022226203 scopus 로고    scopus 로고
    • Mesenchymal stem cells release exosomes that transfer miRNAs to endothelial cells and promote angiogenesis
    • Gong M, Yu B, Wang J, et al. Mesenchymal stem cells release exosomes that transfer miRNAs to endothelial cells and promote angiogenesis. Oncotarget. 2017;8(28):45200-45212.
    • (2017) Oncotarget , vol.8 , Issue.28 , pp. 45200-45212
    • Gong, M.1    Yu, B.2    Wang, J.3
  • 58
    • 84886738545 scopus 로고    scopus 로고
    • Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies
    • Record M, Carayon K, Poirot M, Silvente-Poirot S. Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies. Biochim Biophys Acta. 2014;1841(1):108–120.
    • (2014) Biochim Biophys Acta , vol.1841 , Issue.1 , pp. 108-120
    • Record, M.1    Carayon, K.2    Poirot, M.3    Silvente-Poirot, S.4
  • 59
    • 67049134758 scopus 로고    scopus 로고
    • Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation
    • Hoggatt J, Singh P, Sampath J, Pelus LM. Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation. Blood. 2009;113(22):5444–5455.
    • (2009) Blood , vol.113 , Issue.22 , pp. 5444-5455
    • Hoggatt, J.1    Singh, P.2    Sampath, J.3    Pelus, L.M.4
  • 60
    • 84988613635 scopus 로고    scopus 로고
    • A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods
    • Madrigal M, Rao KS, Riordan NH. A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods. J Transl Med. 2014;12(1):260.
    • (2014) J Transl Med , vol.12 , Issue.1 , pp. 260
    • Madrigal, M.1    Rao, K.S.2    Riordan, N.H.3
  • 61
    • 85008330562 scopus 로고    scopus 로고
    • How do megakaryocytic microparticles target and deliver cargo to alter the fate of hematopoietic stem cells?
    • Jiang J, Kao C-Y, Papoutsakis ET. How do megakaryocytic microparticles target and deliver cargo to alter the fate of hematopoietic stem cells? J Control Release. 2017;247:1–18.
    • (2017) J Control Release , vol.247 , pp. 1-18
    • Jiang, J.1    Kao, C.-Y.2    Papoutsakis, E.T.3
  • 63
    • 85009432124 scopus 로고    scopus 로고
    • Exosomal miR-486 regulates hypoxia-induced erythroid differentiation of erythroleukemia cells through targeting Sirt1
    • Shi X-F, Wang H, Kong F-X, et al. Exosomal miR-486 regulates hypoxia-induced erythroid differentiation of erythroleukemia cells through targeting Sirt1. Exp Cell Res. 2017;351(1):74–81.
    • (2017) Exp Cell Res , vol.351 , Issue.1 , pp. 74-81
    • Shi, X.-F.1    Wang, H.2    Kong, F.-X.3
  • 64
    • 84923378622 scopus 로고    scopus 로고
    • MicroRNA-486 regulates normal erythropoiesis and enhances growth and modulates drug response in CML progenitors
    • Wang L-S, Li L, Li L, et al. MicroRNA-486 regulates normal erythropoiesis and enhances growth and modulates drug response in CML progenitors. Blood. 2015;125(8):1302–1313.
    • (2015) Blood , vol.125 , Issue.8 , pp. 1302-1313
    • Wang, L.-S.1    Li, L.2    Li, L.3
  • 65
    • 85027516950 scopus 로고    scopus 로고
    • MicroRNA-183-5p increases with age in bone-derived extracellular vesicles, suppresses bone marrow stromal (Stem) cell proliferation, and induces stem cell senescence
    • Davis C, Dukes A, Drewry M, et al. MicroRNA-183-5p increases with age in bone-derived extracellular vesicles, suppresses bone marrow stromal (stem) cell proliferation, and induces stem cell senescence. Tissue Eng Part A. 2016.23(21-22);1231-1240.
    • (2016) Tissue Eng Part A , vol.23 , Issue.21-22 , pp. 1231-1240
    • Davis, C.1    Dukes, A.2    Drewry, M.3
  • 66
    • 33646146422 scopus 로고    scopus 로고
    • Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: Evidence for horizontal transfer of mRNA and protein delivery
    • Ratajczak J, Miekus K, Kucia M, et al. Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery. Leukemia. 2006;20(5):847–856.
    • (2006) Leukemia , vol.20 , Issue.5 , pp. 847-856
    • Ratajczak, J.1    Miekus, K.2    Kucia, M.3
  • 67
    • 85014849155 scopus 로고    scopus 로고
    • Leukemia microvesicles affect healthy hematopoietic stem cells
    • 101042831769223
    • Razmkhah F, Soleimani M, Mehrabani D, et al. Leukemia microvesicles affect healthy hematopoietic stem cells. Tumor Biol. 2017;39(2):101042831769223.
    • (2017) Tumor Biol. , vol.39 , Issue.2
    • Razmkhah, F.1    Soleimani, M.2    Mehrabani, D.3
  • 68
    • 84960106140 scopus 로고    scopus 로고
    • Alterations in acute myeloid leukaemia bone marrow stromal cell exosome content coincide with gains in tyrosine kinase inhibitor resistance
    • Viola S, Traer E, Huan J, et al. Alterations in acute myeloid leukaemia bone marrow stromal cell exosome content coincide with gains in tyrosine kinase inhibitor resistance. Br J Haematol. 2015;172(6):938-986
    • (2015) Br J Haematol , vol.172 , Issue.6 , pp. 938-986
    • Viola, S.1    Traer, E.2    Huan, J.3
  • 69
    • 80052384534 scopus 로고    scopus 로고
    • Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1
    • Szczepanski MJ, Szajnik M, Welsh A, Whiteside TL, Boyiadzis M. Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1. Haematologica. 2011;96(9):1302–1309.
    • (2011) Haematologica , vol.96 , Issue.9 , pp. 1302-1309
    • Szczepanski, M.J.1    Szajnik, M.2    Welsh, A.3    Whiteside, T.L.4    Boyiadzis, M.5
  • 70
    • 84962419405 scopus 로고    scopus 로고
    • Extracellular vesicle miR-7977 is involved in hematopoietic dysfunction of mesenchymal stromal cells via poly(RC) binding protein 1 reduction in myeloid neoplasms
    • Horiguchi H, Kobune M, Kikuchi S, et al. Extracellular vesicle miR-7977 is involved in hematopoietic dysfunction of mesenchymal stromal cells via poly(rC) binding protein 1 reduction in myeloid neoplasms. Haematologica. 2016;101(4):437–447.
    • (2016) Haematologica , vol.101 , Issue.4 , pp. 437-447
    • Horiguchi, H.1    Kobune, M.2    Kikuchi, S.3
  • 71
    • 84958794074 scopus 로고    scopus 로고
    • Microvesicles from mesenchymal stromal cells are involved in HPC-microenvironment crosstalk in myelodysplastic patients
    • Wagner W, editor.
    • Muntión S, Ramos TL, Diez-Campelo M, et al. Microvesicles from mesenchymal stromal cells are involved in HPC-microenvironment crosstalk in myelodysplastic patients. Wagner W, editor. PLoS One. 2016;11(2):e0146722.
    • (2016) PloS One , vol.11 , Issue.2
    • Muntión, S.1    Ramos, T.L.2    Diez-Campelo, M.3
  • 72
    • 84971311450 scopus 로고    scopus 로고
    • Chronic myelogenous leukaemia exosomes modulate bone marrow microenvironment through activation of epidermal growth factor receptor
    • Corrado C, Saieva L, Raimondo S, Santoro A, De Leo G, Alessandro R. Chronic myelogenous leukaemia exosomes modulate bone marrow microenvironment through activation of epidermal growth factor receptor. J Cell Mol Med. 2016;20(10):1829–1839.
    • (2016) J Cell Mol Med , vol.20 , Issue.10 , pp. 1829-1839
    • Corrado, C.1    Saieva, L.2    Raimondo, S.3    Santoro, A.4    De Leo, G.5    Alessandro, R.6
  • 73
    • 84862007577 scopus 로고    scopus 로고
    • Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
    • Peinado H, Alečković M, Lavotshkin S, et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med. 2012;18(6):883–891.
    • (2012) Nat Med , vol.18 , Issue.6 , pp. 883-891
    • Peinado, H.1    Alečković, M.2    Lavotshkin, S.3
  • 74
    • 84951838953 scopus 로고    scopus 로고
    • An overview of the role of microparticles/microvesicles in blood components: Are they clinically beneficial or harmful?
    • Burnouf T, Chou M-L, Goubran H, Cognasse F, Garraud O, Seghatchian J. An overview of the role of microparticles/microvesicles in blood components: are they clinically beneficial or harmful? Transfus Apher Sci. 2015;53(2): 137–145.
    • (2015) Transfus Apher Sci , vol.53 , Issue.2 , pp. 137-145
    • Burnouf, T.1    Chou, M.-L.2    Goubran, H.3    Cognasse, F.4    Garraud, O.5    Seghatchian, J.6
  • 75
    • 84952876765 scopus 로고    scopus 로고
    • High serum levels of extracellular vesicles expressing malignancy-related markers are released in patients with various types of hematological neoplastic disorders
    • Caivano A, Laurenzana I, De Luca L, et al. High serum levels of extracellular vesicles expressing malignancy-related markers are released in patients with various types of hematological neoplastic disorders. Tumour Biol. 2015;36(12):9739–9752.
    • (2015) Tumour Biol , vol.36 , Issue.12 , pp. 9739-9752
    • Caivano, A.1    Laurenzana, I.2    De Luca, L.3
  • 76
    • 85020422033 scopus 로고    scopus 로고
    • Extracellular vesicles in hematological malignancies: From biology to therapy
    • Caivano A, La Rocca F, Laurenzana I, et al. Extracellular vesicles in hematological malignancies: from biology to therapy. Int J Mol Sci. 2017;18(6):1183.
    • (2017) Int J Mol Sci , vol.18 , Issue.6 , pp. 1183
    • Caivano, A.1    La Rocca, F.2    Laurenzana, I.3
  • 77
    • 85010207500 scopus 로고    scopus 로고
    • Extensive surface protein profiles of extracellular vesicles from cancer cells may provide diagnostic signatures from blood samples
    • Belov L, Matic KJ, Hallal S, Best OG, Mulligan SP, Christopherson RI. Extensive surface protein profiles of extracellular vesicles from cancer cells may provide diagnostic signatures from blood samples. J Extracell Vesicles. 2016;5(1):e25355.
    • (2016) J Extracell Vesicles , vol.5 , Issue.1
    • Belov, L.1    Matic, K.J.2    Hallal, S.3    Best, O.G.4    Mulligan, S.P.5    Christopherson, R.I.6
  • 78
    • 84991037515 scopus 로고    scopus 로고
    • Characterization and prognostic relevance of circulating microvesicles in chronic lymphocytic leukemia
    • De Luca L, D’Arena G, Simeon V, et al. Characterization and prognostic relevance of circulating microvesicles in chronic lymphocytic leukemia. Leuk Lymphoma. 2017;58(6):1424–1432.
    • (2017) Leuk Lymphoma , vol.58 , Issue.6 , pp. 1424-1432
    • De Luca, L.1    D’Arena, G.2    Simeon, V.3
  • 79
    • 84959266374 scopus 로고    scopus 로고
    • Proteomic characterization of circulating extracellular vesicles identifies novel serum myeloma associated markers
    • Harshman SW, Canella A, Ciarlariello PD, et al. Proteomic characterization of circulating extracellular vesicles identifies novel serum myeloma associated markers. J Proteomics. 2016;136:89–98.
    • (2016) J Proteomics , vol.136 , pp. 89-98
    • Harshman, S.W.1    Canella, A.2    Ciarlariello, P.D.3
  • 80
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi H, Ekström K, Bossios A, Sjöstrand M, Lee JJ, Lötvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007;9(6):654–659.
    • (2007) Nat Cell Biol , vol.9 , Issue.6 , pp. 654-659
    • Valadi, H.1    Ekström, K.2    Bossios, A.3    Sjöstrand, M.4    Lee, J.J.5    Lötvall, J.O.6
  • 81
    • 84931287779 scopus 로고    scopus 로고
    • Serum exosome microRNA as a minimally-invasive early biomarker of AML
    • Hornick NI, Huan J, Doron B, et al. Serum exosome microRNA as a minimally-invasive early biomarker of AML. Sci Rep. 2015;5:11295.
    • (2015) Sci Rep , vol.5 , pp. 11295
    • Hornick, N.I.1    Huan, J.2    Doron, B.3
  • 82
    • 84987762488 scopus 로고    scopus 로고
    • Extracellular microvesicle microRNAs in children with sickle cell anaemia with divergent clinical phenotypes
    • Khalyfa A, Khalyfa AA, Akbarpour M, et al. Extracellular microvesicle microRNAs in children with sickle cell anaemia with divergent clinical phenotypes. Br J Haematol. 2016;174(5):786–798.
    • (2016) Br J Haematol , vol.174 , Issue.5 , pp. 786-798
    • Khalyfa, A.1    Khalyfa, A.A.2    Akbarpour, M.3
  • 83
    • 85008367709 scopus 로고    scopus 로고
    • A plasma microRNA signature as a biomarker for acquired aplastic anemia
    • Hosokawa K, Kajigaya S, Feng X, et al. A plasma microRNA signature as a biomarker for acquired aplastic anemia. Haematologica. 2017;102(1):69–78.
    • (2017) Haematologica , vol.102 , Issue.1 , pp. 69-78
    • Hosokawa, K.1    Kajigaya, S.2    Feng, X.3
  • 84
    • 84987910488 scopus 로고    scopus 로고
    • PGE2/EP4 signaling controls the transfer of the mammary stem cell state by lipid rafts in extracellular vesicles
    • Lin M-C, Chen S-Y, Tsai H-M, et al. PGE2/EP4 signaling controls the transfer of the mammary stem cell state by lipid rafts in extracellular vesicles. Stem Cells. 2017;35(2):425–444.
    • (2017) Stem Cells , vol.35 , Issue.2 , pp. 425-444
    • Lin, M.-C.1    Chen, S.-Y.2    Tsai, H.-M.3
  • 85
    • 84963974153 scopus 로고    scopus 로고
    • Differential and transferable modulatory effects of mesenchymal stromal cell-derived extracellular vesicles on T, B and NK cell functions
    • Di Trapani M, Bassi G, Midolo M, et al. Differential and transferable modulatory effects of mesenchymal stromal cell-derived extracellular vesicles on T, B and NK cell functions. Sci Rep. 2016;6(1):24120.
    • (2016) Sci Rep , vol.6 , Issue.1 , pp. 24120
    • Di Trapani, M.1    Bassi, G.2    Midolo, M.3
  • 86
    • 84925590260 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stromal cells harness purinergenic signaling to tolerize human Th1 cells in vivo
    • Amarnath S, Foley JE, Farthing DE, et al. Bone marrow-derived mesenchymal stromal cells harness purinergenic signaling to tolerize human Th1 cells in vivo. Stem Cells. 2015;33(4):1200–1212.
    • (2015) Stem Cells , vol.33 , Issue.4 , pp. 1200-1212
    • Amarnath, S.1    Foley, J.E.2    Farthing, D.E.3
  • 87
    • 84898039042 scopus 로고    scopus 로고
    • MSC-derived exosomes: A novel tool to treat therapy-refractory graft-versus-host disease
    • Kordelas L, Rebmann V, Ludwig A-K, et al. MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease. Leukemia. 2014;28(4):970–973.
    • (2014) Leukemia , vol.28 , Issue.4 , pp. 970-973
    • Kordelas, L.1    Rebmann, V.2    Ludwig, A.-K.3
  • 88
    • 85033407954 scopus 로고    scopus 로고
    • Rab27-dependent exosome production inhibits chronic inflammation and enables acute responses to inflammatory stimuli
    • Alexander M, Ramstead AG, Bauer KM, et al. Rab27-dependent exosome production inhibits chronic inflammation and enables acute responses to inflammatory stimuli. J Immunol. 2017;199(10):3559–3570.
    • (2017) J Immunol , vol.199 , Issue.10 , pp. 3559-3570
    • Alexander, M.1    Ramstead, A.G.2    Bauer, K.M.3
  • 89
    • 84907225988 scopus 로고    scopus 로고
    • Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs
    • Boyd AL, Campbell CJ, Hopkins CI, et al. Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs. J Exp Med. 2014;211(10):1925–1935.
    • (2014) J Exp Med , vol.211 , Issue.10 , pp. 1925-1935
    • Boyd, A.L.1    Campbell, C.J.2    Hopkins, C.I.3
  • 90
    • 79953331206 scopus 로고    scopus 로고
    • Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow
    • Shiozawa Y, Pedersen EA, Havens AM, et al. Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow. J Clin Invest. 2011;121(4):1298–1312.
    • (2011) J Clin Invest , vol.121 , Issue.4 , pp. 1298-1312
    • Shiozawa, Y.1    Pedersen, E.A.2    Havens, A.M.3
  • 91
    • 33646416463 scopus 로고    scopus 로고
    • The regulation of exosome secretion: A novel function of the p53 protein
    • Yu X, Harris SL, Levine AJ. The regulation of exosome secretion: a novel function of the p53 protein. Cancer Res. 2006;66(9):4795–4801.
    • (2006) Cancer Res , vol.66 , Issue.9 , pp. 4795-4801
    • Yu, X.1    Harris, S.L.2    Levine, A.J.3
  • 92
    • 77949907107 scopus 로고    scopus 로고
    • P53-mediated hematopoietic stem and progenitor cell competition
    • Bondar T, Medzhitov R. p53-mediated hematopoietic stem and progenitor cell competition. Stem Cell. 2010;6(4):309–322.
    • (2010) Stem Cell , vol.6 , Issue.4 , pp. 309-322
    • Bondar, T.1    Medzhitov, R.2
  • 93
    • 78651056338 scopus 로고
    • Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin
    • Slaughter DP, Southwick HW, Smekjal W. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer. 1953;6(5):963–968.
    • (1953) Cancer , vol.6 , Issue.5 , pp. 963-968
    • Slaughter, D.P.1    Southwick, H.W.2    Smekjal, W.3
  • 94
    • 84982793251 scopus 로고    scopus 로고
    • Functional interference in the bone marrow microenvironment by disseminated breast cancer cells
    • Dhawan A, Bonin von M, Bray LJ, et al. Functional interference in the bone marrow microenvironment by disseminated breast cancer cells. Stem Cells. 2016;34(8):2224–2235.
    • (2016) Stem Cells , vol.34 , Issue.8 , pp. 2224-2235
    • Dhawan, A.1    Bonin Von, M.2    Bray, L.J.3
  • 95
    • 27944432476 scopus 로고    scopus 로고
    • Cell-to-cell contact is critical for the survival of hematopoietic progenitor cells on osteoblasts
    • Jung Y, Wang J, Havens A, et al. Cell-to-cell contact is critical for the survival of hematopoietic progenitor cells on osteoblasts. Cytokine. 2005;32(3-4):155–162.
    • (2005) Cytokine , vol.32 , Issue.3-4 , pp. 155-162
    • Jung, Y.1    Wang, J.2    Havens, A.3
  • 96
    • 84904023285 scopus 로고    scopus 로고
    • Chronic variable stress activates hematopoietic stem cells
    • Heidt T, Sager HB, Courties G, et al. Chronic variable stress activates hematopoietic stem cells. Nat Med. 2014;20(7):754–758.
    • (2014) Nat Med , vol.20 , Issue.7 , pp. 754-758
    • Heidt, T.1    Sager, H.B.2    Courties, G.3
  • 97
    • 84934903985 scopus 로고    scopus 로고
    • Exosome-delivered microRNAs modulate the inflammatory response to endotoxin
    • Alexander M, Hu R, Runtsch MC, et al. Exosome-delivered microRNAs modulate the inflammatory response to endotoxin. Nat Commun. 2015;6:7321.
    • (2015) Nat Commun , vol.6 , pp. 7321
    • Alexander, M.1    Hu, R.2    Runtsch, M.C.3
  • 98
    • 84903289462 scopus 로고    scopus 로고
    • Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation
    • Ridder K, Keller S, Dams M, et al. Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation. PLoS Biol. 2014;12(6):1001874.
    • (2014) Plos Biol. , vol.12 , Issue.6 , pp. 1001874
    • Ridder, K.1    Keller, S.2    Dams, M.3
  • 99
    • 84983334837 scopus 로고    scopus 로고
    • Vps33b regulates Vwf-positive vesicular trafficking in megakaryocytes
    • Dai J, Lu Y, Wang C, et al. Vps33b regulates Vwf-positive vesicular trafficking in megakaryocytes. J Pathol. 2016;240(1):108–119.
    • (2016) J Pathol , vol.240 , Issue.1 , pp. 108-119
    • Dai, J.1    Lu, Y.2    Wang, C.3
  • 100
    • 84874268409 scopus 로고    scopus 로고
    • Identification of circulating microRNAs as potential biomarkers for detecting acute myeloid leukemia
    • Zhi F, Cao X, Xie X, et al. Identification of circulating microRNAs as potential biomarkers for detecting acute myeloid leukemia. PLoS One. 2013;8(2):56718.
    • (2013) PloS One , vol.8 , Issue.2 , pp. 56718
    • Zhi, F.1    Cao, X.2    Xie, X.3
  • 101
    • 84983456248 scopus 로고    scopus 로고
    • Characterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signaling
    • Yeh Y-Y, Ozer HG, Lehman AM, et al. Characterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signaling. Blood. 2015;125(21):3297–3305.
    • (2015) Blood , vol.125 , Issue.21 , pp. 3297-3305
    • Yeh, Y.-Y.1    Ozer, H.G.2    Lehman, A.M.3
  • 102
    • 85055608701 scopus 로고    scopus 로고
    • Plasma vesicle miRNAs for therapy response monitoring in Hodgkin lymphoma patients
    • van Eijndhoven MA, Zijlstra JM, Groenewegen NJ, et al. Plasma vesicle miRNAs for therapy response monitoring in Hodgkin lymphoma patients. JCI Insight. 2016;1(19):89631.
    • (2016) JCI Insight , vol.1 , Issue.19 , pp. 89631
    • van Eijndhoven, M.A.1    Zijlstra, J.M.2    Groenewegen, N.J.3
  • 103
    • 85018902695 scopus 로고    scopus 로고
    • Prognostic role of circulating exosomal miRNAs in multiple myeloma
    • Manier S, Liu C-J, Avet-Loiseau H, et al. Prognostic role of circulating exosomal miRNAs in multiple myeloma. Blood. 2017;129(17):2429–2436.
    • (2017) Blood , vol.129 , Issue.17 , pp. 2429-2436
    • Manier, S.1    Liu, C.-J.2    Avet-Loiseau, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.