Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells

EMBO Journal

Volumn 25, Issue 15, 2006, Pages 3515-3523

  Yamazaki, Satoshi ^a,b   Iwama, Atsushi ^a,c   Takayanagi, Shin Ichiro ^a   Morita, Yohei ^a,b   Eto, Koji ^a   Ema, Hideo ^a   Nakauchi, Hiromitsu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b ReproCELL Inc   (Japan)

^c CHIBA UNIVERSITY   (Japan)

Author keywords

Bone marrow niche; FOXO; Hematopoietic stem cells; Hibernation; Lipid raft clustering

Indexed keywords

CD34 ANTIGEN; CYCLIN DEPENDENT KINASE INHIBITOR; CYTOKINE; ERYTHROPOIETIN; KI 67 ANTIGEN; PROTEIN KINASE B; PROTEIN P57; STEM CELL FACTOR; THROMBOPOIETIN; TRANSCRIPTION FACTOR FOXO;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CAENORHABDITIS ELEGANS; CELL ISOLATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; EX VIVO STUDY; HEMATOPOIETIC STEM CELL; HIBERNATION; LIPID RAFT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CAENORHABDITIS ELEGANS; CELL CYCLE; CELLS, CULTURED; CYTOKINES; FLUORESCENT ANTIBODY TECHNIQUE; HEMATOPOIETIC STEM CELLS; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED C57BL; SIGNAL TRANSDUCTION; STEM CELLS;

CAENORHABDITIS ELEGANS;

EID: 33747613351     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601236     Document Type: Article

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