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Volumn 8, Issue MAY, 2017, Pages

Endothelial extracellular vesicles-promises and challenges

Author keywords

Endothelial cells; Exosomes; Extracellular vesicles; Microparticles; Pathology

Indexed keywords

CELL FUNCTION; CELL ISOLATION; ENDOTHELIUM CELL; EXOSOME; HUMAN; NONHUMAN; SHORT SURVEY;

EID: 85019686794     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2017.00275     Document Type: Short Survey
Times cited : (82)

References (131)
  • 1
    • 41749120798 scopus 로고    scopus 로고
    • Phospholipid composition of in vitro endothelial microparticles and their in vivo thrombogenic properties
    • Abid Hussein, M. N., Böing, A. N., Biró, E., Hoek, F. J., Vogel, G. M., Meuleman, D. G., et al. (2008). Phospholipid composition of in vitro endothelial microparticles and their in vivo thrombogenic properties. Thromb. Res. 121, 865-871. doi: 10.1016/j.thromres.2007.08.005
    • (2008) Thromb. Res , vol.121 , pp. 865-871
    • Abid Hussein, M.N.1    Böing, A.N.2    Biró, E.3    Hoek, F.J.4    Vogel, G.M.5    Meuleman, D.G.6
  • 2
    • 84884820963 scopus 로고    scopus 로고
    • International society for extracellular vesicles: first annual meeting, April 17-21, 2012, ISEV-2012
    • Araldi, E., Krämer-Albers, E.-M., Hoen, E. N., Peinado, H., Psonka-Antonczyk, K. M., Rao, P., et al. (2012). International society for extracellular vesicles: first annual meeting, April 17-21, 2012: ISEV-2012. J. Extracell. Vesicles 1:19995. doi: 10.3402/jev.v1i0.19995
    • (2012) J. Extracell. Vesicles , vol.1 , pp. 19995
    • Araldi, E.1    Krämer-Albers, E.-M.2    Hoen, E.N.3    Peinado, H.4    Psonka-Antonczyk, K.M.5    Rao, P.6
  • 3
    • 84898680460 scopus 로고    scopus 로고
    • Extracellular vesicles from blood plasma: determination of their morphology, size, phenotype and concentration
    • Arraud, N., Linares, R., Tan, S., Gounou, C., Pasquet, J.-M., Mornet, S., et al. (2014). Extracellular vesicles from blood plasma: determination of their morphology, size, phenotype and concentration. J. Thromb. Haemost. 12, 614-627. doi: 10.1111/jth.12554
    • (2014) J. Thromb. Haemost , vol.12 , pp. 614-627
    • Arraud, N.1    Linares, R.2    Tan, S.3    Gounou, C.4    Pasquet, J.-M.5    Mornet, S.6
  • 4
    • 84873919177 scopus 로고    scopus 로고
    • Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury
    • Arslan, F., Lai, R. C., Smeets, M. B., Akeroyd, L., Choo, A., Aguor, E. N., et al. (2013). Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury. Stem Cell Res. 10, 301-312. doi: 10.1016/j.scr.2013.01.002
    • (2013) Stem Cell Res , vol.10 , pp. 301-312
    • Arslan, F.1    Lai, R.C.2    Smeets, M.B.3    Akeroyd, L.4    Choo, A.5    Aguor, E.N.6
  • 5
    • 84899621470 scopus 로고    scopus 로고
    • Circulating levels of cell-derived microparticles are reduced by mild hypobaric hypoxia: data from a randomised controlled trial
    • Ayers, L., Stoewhas, A.-C., Ferry, B., Latshang, T. D., Lo Cascio, C. M., Sadler, R., et al. (2014). Circulating levels of cell-derived microparticles are reduced by mild hypobaric hypoxia: data from a randomised controlled trial. Eur. J. Appl. Physiol. 114, 1067-1073. doi: 10.1007/s00421-014-2837-6
    • (2014) Eur. J. Appl. Physiol , vol.114 , pp. 1067-1073
    • Ayers, L.1    Stoewhas, A.-C.2    Ferry, B.3    Latshang, T.D.4    Lo Cascio, C.M.5    Sadler, R.6
  • 6
    • 79551608032 scopus 로고    scopus 로고
    • Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences
    • Balaj, L., Lessard, R., Dai, L., Cho, Y.-J., Pomeroy, S. L., Breakefield, X. O., et al. (2011). Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences. Nat. Commun. 2:180. doi: 10.1038/ncomms1180
    • (2011) Nat. Commun , vol.2 , pp. 180
    • Balaj, L.1    Lessard, R.2    Dai, L.3    Cho, Y.-J.4    Pomeroy, S.L.5    Breakefield, X.O.6
  • 7
    • 0038620493 scopus 로고    scopus 로고
    • High levels of circulating endothelial microparticles in patients with acute coronary syndromes
    • Bernal-Mizrachi, L., Jy, W., Jimenez, J. J., Pastor, J., Mauro, L. M., Horstman, L. L., et al. (2003). High levels of circulating endothelial microparticles in patients with acute coronary syndromes. Am. Heart J. 145, 962-970. doi: 10.1016/S0002-8703(03)00103-0
    • (2003) Am. Heart J , vol.145 , pp. 962-970
    • Bernal-Mizrachi, L.1    Jy, W.2    Jimenez, J.J.3    Pastor, J.4    Mauro, L.M.5    Horstman, L.L.6
  • 8
    • 84898461927 scopus 로고    scopus 로고
    • Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model
    • Bian, S., Zhang, L., Duan, L., Wang, X., Min, Y., and Yu, H. (2014). Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model. J. Mol. Med. Berl. Ger. 92, 387-397. doi: 10.1007/s00109-013-1110-5
    • (2014) J. Mol. Med. Berl. Ger , vol.92 , pp. 387-397
    • Bian, S.1    Zhang, L.2    Duan, L.3    Wang, X.4    Min, Y.5    Yu, H.6
  • 10
    • 34047237415 scopus 로고    scopus 로고
    • In vivo shear stress determines circulating levels of endothelial microparticles in end-stage renal disease
    • Boulanger, C. M., Amabile, N., Guérin, A. P., Pannier, B., Leroyer, A. S., Mallat, Z., et al. (2007). In vivo shear stress determines circulating levels of endothelial microparticles in end-stage renal disease. Hypertension 49, 902-908. doi: 10.1161/01.HYP.0000259667.22309.df
    • (2007) Hypertension , vol.49 , pp. 902-908
    • Boulanger, C.M.1    Amabile, N.2    Guérin, A.P.3    Pannier, B.4    Leroyer, A.S.5    Mallat, Z.6
  • 11
    • 84929603438 scopus 로고    scopus 로고
    • Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer
    • Bovy, N., Blomme, B., Frères, P., Dederen, S., Nivelles, O., Lion, M., et al. (2015). Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer. Oncotarget 6, 10253-10266. doi: 10.18632/oncotarget.3520
    • (2015) Oncotarget , vol.6 , pp. 10253-10266
    • Bovy, N.1    Blomme, B.2    Frères, P.3    Dederen, S.4    Nivelles, O.5    Lion, M.6
  • 12
    • 0037342076 scopus 로고    scopus 로고
    • Circulating microparticles: a marker of procoagulant state in normal pregnancy and pregnancy complicated by preeclampsia or intrauterine growth restriction
    • Bretelle, F., Sabatier, F., Desprez, D., Camoin, L., Grunebaum, L., Combes, V., et al. (2003). Circulating microparticles: a marker of procoagulant state in normal pregnancy and pregnancy complicated by preeclampsia or intrauterine growth restriction. Thromb. Haemost. 89, 486-492
    • (2003) Thromb. Haemost , vol.89 , pp. 486-492
    • Bretelle, F.1    Sabatier, F.2    Desprez, D.3    Camoin, L.4    Grunebaum, L.5    Combes, V.6
  • 13
    • 84962689435 scopus 로고    scopus 로고
    • Liquid biopsy for cancer screening, patient stratification and monitoring
    • Brock, G., Castellanos-Rizaldos, E., Hu, L., Coticchia, C., and Skog, J. (2015). Liquid biopsy for cancer screening, patient stratification and monitoring. Transl. Cancer Res. 4, 280-290. doi: 10.21037/4546
    • (2015) Transl. Cancer Res , vol.4 , pp. 280-290
    • Brock, G.1    Castellanos-Rizaldos, E.2    Hu, L.3    Coticchia, C.4    Skog, J.5
  • 14
    • 0037195054 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 promotes formation of endothelial microparticles with procoagulant potential
    • Brodsky, S. V., Malinowski, K., Golightly, M., Jesty, J., and Goligorsky, M. S. (2002). Plasminogen activator inhibitor-1 promotes formation of endothelial microparticles with procoagulant potential. Circulation 106, 2372-2378. doi: 10.1161/01.CIR.0000033972.90653.AF
    • (2002) Circulation , vol.106 , pp. 2372-2378
    • Brodsky, S.V.1    Malinowski, K.2    Golightly, M.3    Jesty, J.4    Goligorsky, M.S.5
  • 15
    • 1942533438 scopus 로고    scopus 로고
    • Endothelium-derived microparticles impair endothelial function in vitro
    • Brodsky, S. V., Zhang, F., Nasjletti, A., and Goligorsky, M. S. (2004). Endothelium-derived microparticles impair endothelial function in vitro. Am. J. Physiol. 286, H1910-H1915. doi: 10.1152/ajpheart.01172.2003
    • (2004) Am. J. Physiol , vol.286 , pp. H1910-H1915
    • Brodsky, S.V.1    Zhang, F.2    Nasjletti, A.3    Goligorsky, M.S.4
  • 16
    • 84874091042 scopus 로고    scopus 로고
    • Microvesicles derived from human bone marrow mesenchymal stem cells inhibit tumor growth
    • Bruno, S., Collino, F., Deregibus, M. C., Grange, C., Tetta, C., and Camussi, G. (2013). Microvesicles derived from human bone marrow mesenchymal stem cells inhibit tumor growth. Stem Cells Dev. 22, 758-771. doi: 10.1089/scd.2012.0304
    • (2013) Stem Cells Dev , vol.22 , pp. 758-771
    • Bruno, S.1    Collino, F.2    Deregibus, M.C.3    Grange, C.4    Tetta, C.5    Camussi, G.6
  • 18
    • 84918536001 scopus 로고    scopus 로고
    • Proangiogenic compositions of microvesicles derived from human umbilical cord mesenchymal stem cells
    • Chen, J., Liu, Z., Hong, M. M., Zhang, H., Chen, C., Xiao, M., et al. (2014). Proangiogenic compositions of microvesicles derived from human umbilical cord mesenchymal stem cells. PLoS ONE 9:e115316. doi: 10.1371/journal.pone.0115316
    • (2014) PLoS ONE , vol.9
    • Chen, J.1    Liu, Z.2    Hong, M.M.3    Zhang, H.4    Chen, C.5    Xiao, M.6
  • 19
    • 84957545377 scopus 로고    scopus 로고
    • Focus on extracellular vesicles: new frontiers of cell-to-cell communication in cancer
    • Ciardiello, C., Cavallini, L., Spinelli, C., Yang, J., Reis-Sobreiro, M., de Candia, P., et al. (2016). Focus on extracellular vesicles: new frontiers of cell-to-cell communication in cancer. Int. J. Mol. Sci. 17:175. doi: 10.3390/ijms17020175
    • (2016) Int. J. Mol. Sci , vol.17 , pp. 175
    • Ciardiello, C.1    Cavallini, L.2    Spinelli, C.3    Yang, J.4    Reis-Sobreiro, M.5    de Candia, P.6
  • 20
    • 84980397331 scopus 로고    scopus 로고
    • Imaging flow cytometry enhances particle detection sensitivity for extracellular vesicle analysis
    • Clark, R. T. (2015). Imaging flow cytometry enhances particle detection sensitivity for extracellular vesicle analysis. Nat. Methods 12. doi: 10.1038/nmeth.f.380
    • (2015) Nat. Methods , pp. 12
    • Clark, R.T.1
  • 21
    • 84904704297 scopus 로고    scopus 로고
    • Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles
    • Colombo, M., Raposo, G., and Théry, C. (2014). Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu. Rev. Cell Dev. Biol. 30, 255-289. doi: 10.1146/annurev-cellbio-101512-122326
    • (2014) Annu. Rev. Cell Dev. Biol , vol.30 , pp. 255-289
    • Colombo, M.1    Raposo, G.2    Théry, C.3
  • 22
    • 0032694867 scopus 로고    scopus 로고
    • In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant
    • Combes, V., Simon, A.-C., Grau, G.-E., Arnoux, D., Camoin, L., Sabatier, F., et al. (1999). In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant. J. Clin. Invest. 104, 93-102. doi: 10.1172/JCI4985
    • (1999) J. Clin. Invest , vol.104 , pp. 93-102
    • Combes, V.1    Simon, A.-C.2    Grau, G.-E.3    Arnoux, D.4    Camoin, L.5    Sabatier, F.6
  • 23
    • 85024946724 scopus 로고    scopus 로고
    • The influence of rotor type and centrifugation time on the yield and purity of extracellular vesicles
    • Cvjetkovic, A., Lötvall, J., and Lässer, C. (2014). The influence of rotor type and centrifugation time on the yield and purity of extracellular vesicles. J. Extracell. Vesicles 3:23111. doi: 10.3402/jev.v3.23111
    • (2014) J. Extracell. Vesicles , vol.3 , pp. 23111
    • Cvjetkovic, A.1    Lötvall, J.2    Lässer, C.3
  • 24
    • 85013156831 scopus 로고    scopus 로고
    • Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes
    • de Jong, O. G., Verhaar, M. C., Chen, Y., Vader, P., Gremmels, H., Posthuma, G., et al. (2012). Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. J. Extracell. Vesicles 1:18396. doi: 10.3402/jev.v1i0.18396
    • (2012) J. Extracell. Vesicles , vol.1 , pp. 18396
    • de Jong, O.G.1    Verhaar, M.C.2    Chen, Y.3    Vader, P.4    Gremmels, H.5    Posthuma, G.6
  • 25
    • 33750375282 scopus 로고    scopus 로고
    • Endothelium-derived microparticles induce endothelial dysfunction and acute lung injury
    • Densmore, J. C., Signorino, P. R., Ou, J., Hatoum, O. A., Rowe, J. J., Shi, Y., et al. (2006). Endothelium-derived microparticles induce endothelial dysfunction and acute lung injury. Shock Augusta Ga 26, 464-471. doi: 10.1097/01.shk.0000228791.10550.36
    • (2006) Shock Augusta Ga , vol.26 , pp. 464-471
    • Densmore, J.C.1    Signorino, P.R.2    Ou, J.3    Hatoum, O.A.4    Rowe, J.J.5    Shi, Y.6
  • 26
  • 27
    • 84868208632 scopus 로고    scopus 로고
    • Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease
    • Di Vizio, D., Morello, M., Dudley, A. C., Schow, P. W., Adam, R. M., Morley, S., et al. (2012). Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease. Am. J. Pathol. 181, 1573-1584. doi: 10.1016/j.ajpath.2012.07.030
    • (2012) Am. J. Pathol , vol.181 , pp. 1573-1584
    • Di Vizio, D.1    Morello, M.2    Dudley, A.C.3    Schow, P.W.4    Adam, R.M.5    Morley, S.6
  • 28
    • 80055118968 scopus 로고    scopus 로고
    • Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis
    • Dragovic, R. A., Gardiner, C., Brooks, A. S., Tannetta, D. S., Ferguson, D. J., Hole, P., et al. (2011). Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis. Nanomedicine 7, 780-788. doi: 10.1016/j.nano.2011.04.003
    • (2011) Nanomedicine , vol.7 , pp. 780-788
    • Dragovic, R.A.1    Gardiner, C.2    Brooks, A.S.3    Tannetta, D.S.4    Ferguson, D.J.5    Hole, P.6
  • 29
    • 84877585949 scopus 로고    scopus 로고
    • Extracellular vesicles: biology and emerging therapeutic opportunities
    • El Andaloussi, S., Mäger, I., Breakefield, X. O., and Wood, M. J. A. (2013). Extracellular vesicles: biology and emerging therapeutic opportunities. Nat. Rev. Drug Discov. 12, 347-357. doi: 10.1038/nrd3978
    • (2013) Nat. Rev. Drug Discov , vol.12 , pp. 347-357
    • El Andaloussi, S.1    Mäger, I.2    Breakefield, X.O.3    Wood, M.J.A.4
  • 30
    • 84983200491 scopus 로고    scopus 로고
    • Analytical challenges of extracellular vesicle detection: a comparison of different techniques
    • Erdbrügger, U., and Lannigan, J. (2016). Analytical challenges of extracellular vesicle detection: a comparison of different techniques. Cytometry A 89, 123-134. doi: 10.1002/cyto.a.22795
    • (2016) Cytometry A , vol.89 , pp. 123-134
    • Erdbrügger, U.1    Lannigan, J.2
  • 31
    • 33645965258 scopus 로고    scopus 로고
    • Elevation of circulating endothelial microparticles in patients with chronic renal failure
    • Faure, V., Dou, L., Sabatier, F., Cerini, C., Sampol, J., Berland, Y., et al. (2006). Elevation of circulating endothelial microparticles in patients with chronic renal failure. J. Thromb. Haemost. 4, 566-573. doi: 10.1111/j.1538-7836.2005.01780.x
    • (2006) J. Thromb. Haemost , vol.4 , pp. 566-573
    • Faure, V.1    Dou, L.2    Sabatier, F.3    Cerini, C.4    Sampol, J.5    Berland, Y.6
  • 32
    • 84904304045 scopus 로고    scopus 로고
    • Isolation, characterization and potential role in beta cell-endothelium cross-talk of extracellular vesicles released from human pancreatic islets
    • Figliolini, F., Cantaluppi, V., De Lena, M., Beltramo, S., Romagnoli, R., Salizzoni, M., et al. (2014). Isolation, characterization and potential role in beta cell-endothelium cross-talk of extracellular vesicles released from human pancreatic islets. PLoS ONE 9:e102521. doi: 10.1371/journal.pone.0102521
    • (2014) PLoS ONE , vol.9
    • Figliolini, F.1    Cantaluppi, V.2    De Lena, M.3    Beltramo, S.4    Romagnoli, R.5    Salizzoni, M.6
  • 33
    • 84978405472 scopus 로고    scopus 로고
    • Lipid-targeting peptide probes for extracellular vesicles
    • Flynn, A. D., and Yin, H. (2016). Lipid-targeting peptide probes for extracellular vesicles. J. Cell. Physiol. 231, 2327-2332. doi: 10.1002/jcp.25354
    • (2016) J. Cell. Physiol , vol.231 , pp. 2327-2332
    • Flynn, A.D.1    Yin, H.2
  • 34
    • 84988443503 scopus 로고    scopus 로고
    • Size-exclusion chromatography-based isolation minimally alters extracellular vesicles' characteristics compared to precipitating agents
    • Gámez-Valero, A., Monguió-Tortajada, M., Carreras-Planella, L., Franquesa, M., Beyer, K., and Borràs, F. E. (2016). Size-exclusion chromatography-based isolation minimally alters extracellular vesicles' characteristics compared to precipitating agents. Sci. Rep. 6:33641. doi: 10.1038/srep33641
    • (2016) Sci. Rep , vol.6 , pp. 33641
    • Gámez-Valero, A.1    Monguió-Tortajada, M.2    Carreras-Planella, L.3    Franquesa, M.4    Beyer, K.5    Borràs, F.E.6
  • 35
  • 38
    • 84949934993 scopus 로고    scopus 로고
    • As we wait: coping with an imperfect nomenclature for extracellular vesicles
    • Gould, S. J., and Raposo, G. (2013). As we wait: coping with an imperfect nomenclature for extracellular vesicles. J. Extracell. Vesicles 2:20389. doi: 10.3402/jev.v2i0.20389
    • (2013) J. Extracell. Vesicles , vol.2 , pp. 20389
    • Gould, S.J.1    Raposo, G.2
  • 39
    • 79960960417 scopus 로고    scopus 로고
    • Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche
    • Grange, C., Tapparo, M., Collino, F., Vitillo, L., Damasco, C., Deregibus, M. C., et al. (2011). Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Cancer Res. 71, 5346-5356. doi: 10.1158/0008-5472.CAN-11-0241
    • (2011) Cancer Res , vol.71 , pp. 5346-5356
    • Grange, C.1    Tapparo, M.2    Collino, F.3    Vitillo, L.4    Damasco, C.5    Deregibus, M.C.6
  • 40
    • 79960944057 scopus 로고    scopus 로고
    • Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles
    • György, B., Szabó, T. G., Pásztói, M., Pál, Z., Misják, P., Aradi, B., et al. (2011). Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles. Cell. Mol. Life Sci. 68, 2667-2688. doi: 10.1007/s00018-011-0689-3
    • (2011) Cell. Mol. Life Sci , vol.68 , pp. 2667-2688
    • György, B.1    Szabó, T.G.2    Pásztói, M.3    Pál, Z.4    Misják, P.5    Aradi, B.6
  • 42
    • 84902277709 scopus 로고    scopus 로고
    • Cutting-edge analysis of extracellular microparticles using imagestreamX imaging flow cytometry
    • Headland, S. E., Jones, H. R., D'Sa, A. S., Perretti, M., and Norling, L. V. (2014). Cutting-edge analysis of extracellular microparticles using imagestreamX imaging flow cytometry. Sci. Rep. 4:5237. doi: 10.1038/srep05237
    • (2014) Sci. Rep , vol.4 , pp. 5237
    • Headland, S.E.1    Jones, H.R.2    D'Sa, A.S.3    Perretti, M.4    Norling, L.V.5
  • 43
    • 0033485648 scopus 로고    scopus 로고
    • Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules
    • Heijnen, H. F., Schiel, A. E., Fijnheer, R., Geuze, H. J., and Sixma, J. J. (1999). Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. Blood 94, 3791-3799
    • (1999) Blood , vol.94 , pp. 3791-3799
    • Heijnen, H.F.1    Schiel, A.E.2    Fijnheer, R.3    Geuze, H.J.4    Sixma, J.J.5
  • 44
    • 84875161279 scopus 로고    scopus 로고
    • High glucose condition increases NADPH oxidase activity in endothelial microparticles that promote vascular inflammation
    • Jansen, F., Yang, X., Franklin, B. S., Hoelscher, M., Schmitz, T., Bedorf, J., et al. (2013). High glucose condition increases NADPH oxidase activity in endothelial microparticles that promote vascular inflammation. Cardiovasc. Res. 98, 94-106. doi: 10.1093/cvr/cvt013
    • (2013) Cardiovasc. Res , vol.98 , pp. 94-106
    • Jansen, F.1    Yang, X.2    Franklin, B.S.3    Hoelscher, M.4    Schmitz, T.5    Bedorf, J.6
  • 45
    • 85010886781 scopus 로고    scopus 로고
    • Release of endothelial cell associated VEGFR2 during TGF-ß modulated angiogenesis in vitro
    • Jarad, M., Kuczynski, E. A., Morrison, J., Viloria-Petit, A. M., and Coomber, B. L. (2017). Release of endothelial cell associated VEGFR2 during TGF-ß modulated angiogenesis in vitro. BMC Cell Biol. 18:10. doi: 10.1186/s12860-017-0127-y
    • (2017) BMC Cell Biol , vol.18 , pp. 10
    • Jarad, M.1    Kuczynski, E.A.2    Morrison, J.3    Viloria-Petit, A.M.4    Coomber, B.L.5
  • 46
    • 84874365843 scopus 로고    scopus 로고
    • Disturbed blood flow acutely induces activation and apoptosis of the human vascular endothelium
    • Jenkins, N. T., Padilla, J., Boyle, L. J., Credeur, D. P., Laughlin, M. H., and Fadel, P. J. (2013). Disturbed blood flow acutely induces activation and apoptosis of the human vascular endothelium. Hypertension 61, 615-621. doi: 10.1161/HYPERTENSIONAHA.111.00561
    • (2013) Hypertension , vol.61 , pp. 615-621
    • Jenkins, N.T.1    Padilla, J.2    Boyle, L.J.3    Credeur, D.P.4    Laughlin, M.H.5    Fadel, P.J.6
  • 48
    • 0035138106 scopus 로고    scopus 로고
    • Elevated endothelial microparticles in thrombotic thrombocytopenic purpura: findings from brain and renal microvascular cell culture and patients with active disease
    • Jimenez, J. J., Jy, W., Mauro, L. M., Horstman, L. L., and Ahn, Y. S. (2001). Elevated endothelial microparticles in thrombotic thrombocytopenic purpura: findings from brain and renal microvascular cell culture and patients with active disease. Br. J. Haematol. 112, 81-90. doi: 10.1046/j.1365-2141.2001.02516.x
    • (2001) Br. J. Haematol , vol.112 , pp. 81-90
    • Jimenez, J.J.1    Jy, W.2    Mauro, L.M.3    Horstman, L.L.4    Ahn, Y.S.5
  • 51
    • 0036830046 scopus 로고    scopus 로고
    • Extracellular membrane vesicles from tumor cells promote angiogenesis via sphingomyelin
    • Kim, C. W., Lee, H. M., Lee, T. H., Kang, C., Kleinman, H. K., and Gho, Y. S. (2002). Extracellular membrane vesicles from tumor cells promote angiogenesis via sphingomyelin. Cancer Res. 62, 6312-6317
    • (2002) Cancer Res , vol.62 , pp. 6312-6317
    • Kim, C.W.1    Lee, H.M.2    Lee, T.H.3    Kang, C.4    Kleinman, H.K.5    Gho, Y.S.6
  • 52
    • 84938592995 scopus 로고    scopus 로고
    • Shear stress-induced mitochondrial biogenesis decreases the release of microparticles from endothelial cells
    • Kim, J.-S., Kim, B., Lee, H., Thakkar, S., Babbitt, D. M., Eguchi, S., et al. (2015). Shear stress-induced mitochondrial biogenesis decreases the release of microparticles from endothelial cells. Am. J. Physiol. 309, H425-H433. doi: 10.1152/ajpheart.00438.2014
    • (2015) Am. J. Physiol , vol.309 , pp. H425-H433
    • Kim, J.-S.1    Kim, B.2    Lee, H.3    Thakkar, S.4    Babbitt, D.M.5    Eguchi, S.6
  • 53
    • 21044438176 scopus 로고    scopus 로고
    • Elevated levels of VE-cadherin-positive endothelial microparticles in patients with type 2 diabetes mellitus and coronary artery disease
    • Koga, H., Sugiyama, S., Kugiyama, K., Watanabe, K., Fukushima, H., Tanaka, T., et al. (2005). Elevated levels of VE-cadherin-positive endothelial microparticles in patients with type 2 diabetes mellitus and coronary artery disease. J. Am. Coll. Cardiol. 45, 1622-1630. doi: 10.1016/j.jacc.2005.02.047
    • (2005) J. Am. Coll. Cardiol , vol.45 , pp. 1622-1630
    • Koga, H.1    Sugiyama, S.2    Kugiyama, K.3    Watanabe, K.4    Fukushima, H.5    Tanaka, T.6
  • 54
    • 84922762082 scopus 로고    scopus 로고
    • Exosomes: vehicles of intercellular signaling, biomarkers, and vectors of cell therapy
    • Kourembanas, S. (2015). Exosomes: vehicles of intercellular signaling, biomarkers, and vectors of cell therapy. Annu. Rev. Physiol. 77, 13-27. doi: 10.1146/annurev-physiol-021014-071641
    • (2015) Annu. Rev. Physiol , vol.77 , pp. 13-27
    • Kourembanas, S.1
  • 55
    • 84959386845 scopus 로고    scopus 로고
    • Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
    • Kowal, J., Arras, G., Colombo, M., Jouve, M., Morath, J. P., Primdal-Bengtson, B., et al. (2016). Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes. Proc. Natl. Acad. Sci. U.S.A. 113, E968-E977. doi: 10.1073/pnas.1521230113
    • (2016) Proc. Natl. Acad. Sci. U.S.A , vol.113 , pp. E968-E977
    • Kowal, J.1    Arras, G.2    Colombo, M.3    Jouve, M.4    Morath, J.P.5    Primdal-Bengtson, B.6
  • 56
    • 70350225564 scopus 로고    scopus 로고
    • Acute coronary syndromes: diagnosis and management, part I
    • Kumar, A., and Cannon, C. P. (2009). Acute coronary syndromes: diagnosis and management, part I. Mayo Clin. Proc. 84, 917-938. doi: 10.4065/84.10.917
    • (2009) Mayo Clin. Proc , vol.84 , pp. 917-938
    • Kumar, A.1    Cannon, C.P.2
  • 57
    • 34948812510 scopus 로고    scopus 로고
    • Activation of plasminogen into plasmin at the surface of endothelial microparticles: a mechanism that modulates angiogenic properties of endothelial progenitor cells in vitro
    • Lacroix, R., Sabatier, F., Mialhe, A., Basire, A., Pannell, R., Borghi, H., et al. (2007). Activation of plasminogen into plasmin at the surface of endothelial microparticles: a mechanism that modulates angiogenic properties of endothelial progenitor cells in vitro. Blood 110, 2432-2439. doi: 10.1182/blood-2007-02-069997
    • (2007) Blood , vol.110 , pp. 2432-2439
    • Lacroix, R.1    Sabatier, F.2    Mialhe, A.3    Basire, A.4    Pannell, R.5    Borghi, H.6
  • 58
    • 77952293014 scopus 로고    scopus 로고
    • Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
    • Lai, R. C., Arslan, F., Lee, M. M., Sze, N. S. K., Choo, A., Chen, T. S., et al. (2010). Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury. Stem Cell Res. 4, 214-222. doi: 10.1016/j.scr.2009.12.003
    • (2010) Stem Cell Res , vol.4 , pp. 214-222
    • Lai, R.C.1    Arslan, F.2    Lee, M.M.3    Sze, N.S.K.4    Choo, A.5    Chen, T.S.6
  • 59
    • 84894211631 scopus 로고    scopus 로고
    • Exosomes derived from mesenchymal stem cells suppress angiogenesis by down-regulating VEGF expression in breast cancer cells
    • Lee, J.-K., Park, S.-R., Jung, B.-K., Jeon, Y.-K., Lee, Y.-S., Kim, M.-K., et al. (2013). Exosomes derived from mesenchymal stem cells suppress angiogenesis by down-regulating VEGF expression in breast cancer cells. PLoS ONE 8:e84256. doi: 10.1371/journal.pone.0084256
    • (2013) PLoS ONE , vol.8
    • Lee, J.-K.1    Park, S.-R.2    Jung, B.-K.3    Jeon, Y.-K.4    Lee, Y.-S.5    Kim, M.-K.6
  • 60
    • 84946222843 scopus 로고    scopus 로고
    • Simulated temporary hypoxia triggers the release of CD31+/Annexin+ endothelial microparticles: a prospective pilot study in humans
    • Lichtenauer, M., Goebel, B., Fritzenwanger, M., Förster, M., Betge, S., Lauten, A., et al. (2015). Simulated temporary hypoxia triggers the release of CD31+/Annexin+ endothelial microparticles: a prospective pilot study in humans. Clin. Hemorheol. Microcirc. 61, 83-90. doi: 10.3233/CH-141908
    • (2015) Clin. Hemorheol. Microcirc , vol.61 , pp. 83-90
    • Lichtenauer, M.1    Goebel, B.2    Fritzenwanger, M.3    Förster, M.4    Betge, S.5    Lauten, A.6
  • 61
    • 84983549222 scopus 로고    scopus 로고
    • High-speed centrifugation induces aggregation of extracellular vesicles
    • Linares, R., Tan, S., Gounou, C., Arraud, N., and Brisson, A. R. (2015). High-speed centrifugation induces aggregation of extracellular vesicles. J. Extracell. Vesicles 4:29509. doi: 10.3402/jev.v4.29509
    • (2015) J. Extracell. Vesicles , vol.4 , pp. 29509
    • Linares, R.1    Tan, S.2    Gounou, C.3    Arraud, N.4    Brisson, A.R.5
  • 62
    • 84873857031 scopus 로고    scopus 로고
    • Proteomic analysis of TNF-a-activated endothelial cells and endothelial microparticles
    • Liu, Y., Huang, W., Zhang, R., Wu, J., Li, L., and Tang, Y. (2013). Proteomic analysis of TNF-a-activated endothelial cells and endothelial microparticles. Mol. Med. Rep. 7, 318-326. doi: 10.3892/mmr.2012.1139
    • (2013) Mol. Med. Rep , vol.7 , pp. 318-326
    • Liu, Y.1    Huang, W.2    Zhang, R.3    Wu, J.4    Li, L.5    Tang, Y.6
  • 63
    • 84899585740 scopus 로고    scopus 로고
    • Platelet-derived growth factor regulates the secretion of extracellular vesicles by adipose mesenchymal stem cells and enhances their angiogenic potential
    • Lopatina, T., Bruno, S., Tetta, C., Kalinina, N., Porta, M., and Camussi, G. (2014). Platelet-derived growth factor regulates the secretion of extracellular vesicles by adipose mesenchymal stem cells and enhances their angiogenic potential. Cell Commun. Signal. 12:26. doi: 10.1186/1478-811X-12-26
    • (2014) Cell Commun. Signal , vol.12 , pp. 26
    • Lopatina, T.1    Bruno, S.2    Tetta, C.3    Kalinina, N.4    Porta, M.5    Camussi, G.6
  • 64
    • 84973514644 scopus 로고    scopus 로고
    • Cross talk between cancer and mesenchymal stem cells through extracellular vesicles carrying nucleic acids
    • Lopatina, T., Gai, C., Deregibus, M. C., Kholia, S., and Camussi, G. (2016). Cross talk between cancer and mesenchymal stem cells through extracellular vesicles carrying nucleic acids. Front. Oncol. 6:125. doi: 10.3389/fonc.2016.00125
    • (2016) Front. Oncol , vol.6 , pp. 125
    • Lopatina, T.1    Gai, C.2    Deregibus, M.C.3    Kholia, S.4    Camussi, G.5
  • 65
    • 85016448020 scopus 로고    scopus 로고
    • Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles
    • Lötvall, J., Hill, A. F., Hochberg, F., Buzás, E. I., Di Vizio, D., Gardiner, C., et al. (2014). Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles. J. Extracell. Vesicles 3:26913. doi: 10.3402/jev.v3.26913
    • (2014) J. Extracell. Vesicles , vol.3 , pp. 26913
    • Lötvall, J.1    Hill, A.F.2    Hochberg, F.3    Buzás, E.I.4    Di Vizio, D.5    Gardiner, C.6
  • 66
    • 85008146360 scopus 로고    scopus 로고
    • Extracellular vesicles: unique intercellular delivery vehicles
    • Maas, S. L. N., Breakefield, X. O., and Weaver, A. M. (2017). Extracellular vesicles: unique intercellular delivery vehicles. Trends Cell Biol. 27, 172-188. doi: 10.1016/j.tcb.2016.11.003
    • (2017) Trends Cell Biol , vol.27 , pp. 172-188
    • Maas, S.L.N.1    Breakefield, X.O.2    Weaver, A.M.3
  • 67
    • 84920736138 scopus 로고    scopus 로고
    • Possibilities and limitations of current technologies for quantification of biological extracellular vesicles and synthetic mimics
    • Maas, S. L., de Vrij, J., van der Vlist, E. J., Geragousian, B., van Bloois, L., Mastrobattista, E., et al. (2015). Possibilities and limitations of current technologies for quantification of biological extracellular vesicles and synthetic mimics. J. Control. Release 200, 87-96. doi: 10.1016/j.jconrel.2014.12.041
    • (2015) J. Control. Release , vol.200 , pp. 87-96
    • Maas, S.L.1    de Vrij, J.2    van der Vlist, E.J.3    Geragousian, B.4    van Bloois, L.5    Mastrobattista, E.6
  • 68
    • 0033999142 scopus 로고    scopus 로고
    • Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes
    • Mallat, Z., Benamer, H., Hugel, B., Benessiano, J., Steg, P. G., Freyssinet, J.-M., et al. (2000). Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes. Circulation 101, 841-843. doi: 10.1161/01.CIR.101.8.841
    • (2000) Circulation , vol.101 , pp. 841-843
    • Mallat, Z.1    Benamer, H.2    Hugel, B.3    Benessiano, J.4    Steg, P.G.5    Freyssinet, J.-M.6
  • 69
    • 84888881590 scopus 로고    scopus 로고
    • Impact of endothelial microparticles on coagulation, inflammation, and angiogenesis in age-related vascular diseases
    • Markiewicz, M., Richard, E., Marks, N., and Ludwicka-Bradley, A. (2013). Impact of endothelial microparticles on coagulation, inflammation, and angiogenesis in age-related vascular diseases. J. Aging Res. 2013, 1-11. doi: 10.1155/2013/734509
    • (2013) J. Aging Res , vol.2013 , pp. 1-11
    • Markiewicz, M.1    Richard, E.2    Marks, N.3    Ludwicka-Bradley, A.4
  • 70
    • 84865477117 scopus 로고    scopus 로고
    • Melanoma cell-derived exosomes alter macrophage and dendritic cell functions in vitro
    • Marton, A., Vizler, C., Kusz, E., Temesfoi, V., Szathmary, Z., Nagy, K., et al. (2012). Melanoma cell-derived exosomes alter macrophage and dendritic cell functions in vitro. Immunol. Lett. 148, 34-38. doi: 10.1016/j.imlet.2012.07.006
    • (2012) Immunol. Lett , vol.148 , pp. 34-38
    • Marton, A.1    Vizler, C.2    Kusz, E.3    Temesfoi, V.4    Szathmary, Z.5    Nagy, K.6
  • 71
    • 77956404647 scopus 로고    scopus 로고
    • Exosomes: extracellular organelles important in intercellular communication
    • Mathivanan, S., Ji, H., and Simpson, R. J. (2010). Exosomes: extracellular organelles important in intercellular communication. J. Proteomics 73, 1907-1920. doi: 10.1016/j.jprot.2010.06.006
    • (2010) J. Proteomics , vol.73 , pp. 1907-1920
    • Mathivanan, S.1    Ji, H.2    Simpson, R.J.3
  • 73
    • 23944476083 scopus 로고    scopus 로고
    • Endothelial microparticles affect angiogenesis in vitro: role of oxidative stress
    • Mezentsev, A., Merks, R. M. H., O'Riordan, E., Chen, J., Mendelev, N., Goligorsky, M. S., et al. (2005). Endothelial microparticles affect angiogenesis in vitro: role of oxidative stress. Am. J. Physiol. 289, H1106-H1114. doi: 10.1152/ajpheart.00265.2005
    • (2005) Am. J. Physiol , vol.289 , pp. H1106-H1114
    • Mezentsev, A.1    Merks, R.M.H.2    O'Riordan, E.3    Chen, J.4    Mendelev, N.5    Goligorsky, M.S.6
  • 74
    • 0035933189 scopus 로고    scopus 로고
    • Elevated plasma endothelial microparticles in multiple sclerosis
    • Minagar, A., Jy, W., Jimenez, J. J., Sheremata, W. A., Mauro, L. M., Mao, W. W., et al. (2001). Elevated plasma endothelial microparticles in multiple sclerosis. Neurology 56, 1319-1324. doi: 10.1212/WNL.56.10.1319
    • (2001) Neurology , vol.56 , pp. 1319-1324
    • Minagar, A.1    Jy, W.2    Jimenez, J.J.3    Sheremata, W.A.4    Mauro, L.M.5    Mao, W.W.6
  • 75
    • 84929292388 scopus 로고    scopus 로고
    • Extracellular vesicles in cancer: exosomes, microvesicles and the emerging role of large oncosomes
    • Minciacchi, V. R., Freeman, M. R., and Di Vizio, D. (2015). Extracellular vesicles in cancer: exosomes, microvesicles and the emerging role of large oncosomes. Semin. Cell Dev. Biol. 40, 41-51. doi: 10.1016/j.semcdb.2015.02.010
    • (2015) Semin. Cell Dev. Biol , vol.40 , pp. 41-51
    • Minciacchi, V.R.1    Freeman, M.R.2    Di Vizio, D.3
  • 77
    • 85013654823 scopus 로고    scopus 로고
    • Routes and mechanisms of extracellular vesicle uptake
    • Mulcahy, L. A., Pink, R. C., and Carter, D. R. F. (2014). Routes and mechanisms of extracellular vesicle uptake. J. Extracell. Vesicles 3:24641. doi: 10.3402/jev.v3.24641
    • (2014) J. Extracell. Vesicles , vol.3 , pp. 24641
    • Mulcahy, L.A.1    Pink, R.C.2    Carter, D.R.F.3
  • 78
    • 34948874323 scopus 로고    scopus 로고
    • T cell-induced secretion of MHC class II-peptide complexes on B cell exosomes
    • Muntasell, A., Berger, A. C., and Roche, P. A. (2007). T cell-induced secretion of MHC class II-peptide complexes on B cell exosomes. EMBO J. 26, 4263-4272. doi: 10.1038/sj.emboj.7601842
    • (2007) EMBO J , vol.26 , pp. 4263-4272
    • Muntasell, A.1    Berger, A.C.2    Roche, P.A.3
  • 79
    • 84936766922 scopus 로고    scopus 로고
    • Mesenchymal-stem-cell-derived exosomes accelerate skeletal muscle regeneration
    • Nakamura, Y., Miyaki, S., Ishitobi, H., Matsuyama, S., Nakasa, T., Kamei, N., et al. (2015). Mesenchymal-stem-cell-derived exosomes accelerate skeletal muscle regeneration. FEBS Lett. 589, 1257-1265. doi: 10.1016/j.febslet.2015.03.031
    • (2015) FEBS Lett , vol.589 , pp. 1257-1265
    • Nakamura, Y.1    Miyaki, S.2    Ishitobi, H.3    Matsuyama, S.4    Nakasa, T.5    Kamei, N.6
  • 80
    • 84955605332 scopus 로고    scopus 로고
    • Hijacking the cellular mail: exosome mediated differentiation of mesenchymal stem cells
    • Narayanan, R., Huang, C.-C., and Ravindran, S. (2016). Hijacking the cellular mail: exosome mediated differentiation of mesenchymal stem cells. Stem Cells Int. 2016:e3808674. doi: 10.1155/2016/3808674
    • (2016) Stem Cells Int , vol.2016
    • Narayanan, R.1    Huang, C.-C.2    Ravindran, S.3
  • 81
    • 76749106591 scopus 로고    scopus 로고
    • Cell surface tetraspanin tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation
    • Nazarenko, I., Rana, S., Baumann, A., McAlear, J., Hellwig, A., Trendelenburg, M., et al. (2010). Cell surface tetraspanin tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Cancer Res. 70, 1668-1678. doi: 10.1158/0008-5472.CAN-09-2470
    • (2010) Cancer Res , vol.70 , pp. 1668-1678
    • Nazarenko, I.1    Rana, S.2    Baumann, A.3    McAlear, J.4    Hellwig, A.5    Trendelenburg, M.6
  • 82
    • 0037269761 scopus 로고    scopus 로고
    • Arterial wall shear stress: observations from the bench to the bedside
    • Paszkowiak, J. J., and Dardik, A. (2003). Arterial wall shear stress: observations from the bench to the bedside. Vasc. Endovascular Surg. 37, 47-57. doi: 10.1177/153857440303700107
    • (2003) Vasc. Endovascular Surg , vol.37 , pp. 47-57
    • Paszkowiak, J.J.1    Dardik, A.2
  • 83
    • 48249091633 scopus 로고    scopus 로고
    • Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles
    • Peterson, D. B., Sander, T., Kaul, S., Wakim, B. T., Halligan, B., Twigger, S., et al. (2008). Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Proteomics 8, 2430-2446. doi: 10.1002/pmic.200701029
    • (2008) Proteomics , vol.8 , pp. 2430-2446
    • Peterson, D.B.1    Sander, T.2    Kaul, S.3    Wakim, B.T.4    Halligan, B.5    Twigger, S.6
  • 84
    • 84864408404 scopus 로고    scopus 로고
    • Endothelial microparticles and the antiangiogenic state in preeclampsia and the postpartum period
    • Petrozella, L., Mahendroo, M., Timmons, B., Roberts, S., McIntire, D., and Alexander, J. M. (2012). Endothelial microparticles and the antiangiogenic state in preeclampsia and the postpartum period. Am. J. Obstet. Gynecol. 207, 140.e20-140.e26. doi: 10.1016/j.ajog.2012.06.011
    • (2012) Am. J. Obstet. Gynecol , vol.207 , pp. 140.e20-140.e26
    • Petrozella, L.1    Mahendroo, M.2    Timmons, B.3    Roberts, S.4    McIntire, D.5    Alexander, J.M.6
  • 85
    • 84955563911 scopus 로고    scopus 로고
    • Increased endothelial microparticles and oxidative stress at extreme altitude
    • Pichler Hefti, J., Leichtle, A., Stutz, M., Hefti, U., Geiser, T., Huber, A. R., et al. (2016). Increased endothelial microparticles and oxidative stress at extreme altitude. Eur. J. Appl. Physiol. 116, 739-748. doi: 10.1007/s00421-015-3309-3
    • (2016) Eur. J. Appl. Physiol , vol.116 , pp. 739-748
    • Pichler Hefti, J.1    Leichtle, A.2    Stutz, M.3    Hefti, U.4    Geiser, T.5    Huber, A.R.6
  • 86
    • 84863439963 scopus 로고    scopus 로고
    • Toward tailored exosomes: the exosomal tetraspanin web contributes to target cell selection
    • Rana, S., Yue, S., Stadel, D., and Zöller, M. (2012). Toward tailored exosomes: the exosomal tetraspanin web contributes to target cell selection. Int. J. Biochem. Cell Biol. 44, 1574-1584. doi: 10.1016/j.biocel.2012.06.018
    • (2012) Int. J. Biochem. Cell Biol , vol.44 , pp. 1574-1584
    • Rana, S.1    Yue, S.2    Stadel, D.3    Zöller, M.4
  • 88
    • 84926252899 scopus 로고    scopus 로고
    • Extracellular RNA mediates and marks cancer progression
    • Redzic, J. S., Balaj, L., van der Vos, K. E., and Breakefield, X. O. (2014). Extracellular RNA mediates and marks cancer progression. Semin. Cancer Biol. 28, 14-23. doi: 10.1016/j.semcancer.2014.04.010
    • (2014) Semin. Cancer Biol , vol.28 , pp. 14-23
    • Redzic, J.S.1    Balaj, L.2    van der Vos, K.E.3    Breakefield, X.O.4
  • 89
    • 84963961500 scopus 로고    scopus 로고
    • ExtraPEG: a polyethylene glycol-based method for enrichment of extracellular vesicles
    • Rider, M. A., Hurwitz, S. N., and Meckes, D. G. (2016). ExtraPEG: a polyethylene glycol-based method for enrichment of extracellular vesicles. Sci. Rep. 6:23978. doi: 10.1038/srep23978
    • (2016) Sci. Rep , vol.6 , pp. 23978
    • Rider, M.A.1    Hurwitz, S.N.2    Meckes, D.G.3
  • 90
    • 85013191719 scopus 로고    scopus 로고
    • Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism
    • Royo, F., Moreno, L., Mleczko, J., Palomo, L., Gonzalez, E., Cabrera, D., et al. (2017). Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism. Sci. Rep. 7:42798. doi: 10.1038/srep42798
    • (2017) Sci. Rep , vol.7 , pp. 42798
    • Royo, F.1    Moreno, L.2    Mleczko, J.3    Palomo, L.4    Gonzalez, E.5    Cabrera, D.6
  • 91
    • 0036724722 scopus 로고    scopus 로고
    • Type 1 and type 2 diabetic patients display different patterns of cellular microparticles
    • Sabatier, F., Darmon, P., Hugel, B., Combes, V., Sanmarco, M., Velut, J.-G., et al. (2002a). Type 1 and type 2 diabetic patients display different patterns of cellular microparticles. Diabetes 51, 2840-2845. doi: 10.2337/diabetes.51.9.2840
    • (2002) Diabetes , vol.51 , pp. 2840-2845
    • Sabatier, F.1    Darmon, P.2    Hugel, B.3    Combes, V.4    Sanmarco, M.5    Velut, J.-G.6
  • 92
    • 0036624734 scopus 로고    scopus 로고
    • Interaction of endothelial microparticles with monocytic cells in vitro induces tissue factor-dependent procoagulant activity
    • Sabatier, F., Roux, V., Anfosso, F., Camoin, L., Sampol, J., and Dignat-George, F. (2002b). Interaction of endothelial microparticles with monocytic cells in vitro induces tissue factor-dependent procoagulant activity. Blood 99, 3962-3970. doi: 10.1182/blood. V99.11.3962
    • (2002) Blood , vol.99 , pp. 3962-3970
    • Sabatier, F.1    Roux, V.2    Anfosso, F.3    Camoin, L.4    Sampol, J.5    Dignat-George, F.6
  • 93
    • 84969963050 scopus 로고    scopus 로고
    • The potential of endurance exercise-derived exosomes to treat metabolic diseases
    • Safdar, A., Saleem, A., and Tarnopolsky, M. A. (2016). The potential of endurance exercise-derived exosomes to treat metabolic diseases. Nat. Rev. Endocrinol. 12, 504-517. doi: 10.1038/nrendo.2016.76
    • (2016) Nat. Rev. Endocrinol , vol.12 , pp. 504-517
    • Safdar, A.1    Saleem, A.2    Tarnopolsky, M.A.3
  • 94
    • 33748705954 scopus 로고    scopus 로고
    • Thrombin-induced endothelial microparticle generation: identification of a novel pathway involving ROCK-II activation by caspase-2
    • Sapet, C., Simoncini, S., Loriod, B., Puthier, D., Sampol, J., Nguyen, C., et al. (2006). Thrombin-induced endothelial microparticle generation: identification of a novel pathway involving ROCK-II activation by caspase-2. Blood 108, 1868-1876. doi: 10.1182/blood-2006-04-014175
    • (2006) Blood , vol.108 , pp. 1868-1876
    • Sapet, C.1    Simoncini, S.2    Loriod, B.3    Puthier, D.4    Sampol, J.5    Nguyen, C.6
  • 95
    • 85012283303 scopus 로고    scopus 로고
    • Dimensional characterization of extracellular vesicles using atomic force microscopy
    • Sebaihi, N., De Boeck, B., Yuana, Y., Nieuwland, R., and Pétry, J. (2017). Dimensional characterization of extracellular vesicles using atomic force microscopy. Meas. Sci. Technol. 28:34006. doi: 10.1088/1361-6501/28/3/034006
    • (2017) Meas. Sci. Technol , vol.28 , pp. 34006
    • Sebaihi, N.1    De Boeck, B.2    Yuana, Y.3    Nieuwland, R.4    Pétry, J.5
  • 96
    • 24644485206 scopus 로고    scopus 로고
    • Mature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responses
    • Segura, E., Amigorena, S., and Théry, C. (2005). Mature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responses. Blood Cells. Mol. Dis. 35, 89-93. doi: 10.1016/j.bcmd.2005.05.003
    • (2005) Blood Cells. Mol. Dis , vol.35 , pp. 89-93
    • Segura, E.1    Amigorena, S.2    Théry, C.3
  • 97
    • 77957708340 scopus 로고    scopus 로고
    • New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes
    • Sheldon, H., Heikamp, E., Turley, H., Dragovic, R., Thomas, P., Oon, C. E., et al. (2010). New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes. Blood 116, 2385-2394. doi: 10.1182/blood-2009-08-239228
    • (2010) Blood , vol.116 , pp. 2385-2394
    • Sheldon, H.1    Heikamp, E.2    Turley, H.3    Dragovic, R.4    Thomas, P.5    Oon, C.E.6
  • 98
    • 0141705303 scopus 로고    scopus 로고
    • Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes
    • Shet, A. S., Aras, O., Gupta, K., Hass, M. J., Rausch, D. J., Saba, N., et al. (2003). Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes. Blood 102, 2678-2683. doi: 10.1182/blood-2003-03-0693
    • (2003) Blood , vol.102 , pp. 2678-2683
    • Shet, A.S.1    Aras, O.2    Gupta, K.3    Hass, M.J.4    Rausch, D.J.5    Saba, N.6
  • 100
    • 84973520076 scopus 로고    scopus 로고
    • Purification of HIV-1 gag virus-like particles and separation of other extracellular particles
    • Steppert, P., Burgstaller, D., Klausberger, M., Berger, E., Aguilar, P. P., Schneider, T. A., et al. (2016). Purification of HIV-1 gag virus-like particles and separation of other extracellular particles. J. Chromatogr. A 1455, 93-101. doi: 10.1016/j.chroma.2016.05.053
    • (2016) J. Chromatogr. A , vol.1455 , pp. 93-101
    • Steppert, P.1    Burgstaller, D.2    Klausberger, M.3    Berger, E.4    Aguilar, P.P.5    Schneider, T.A.6
  • 101
    • 0036887580 scopus 로고    scopus 로고
    • Cells in focus: endothelial cell
    • Sumpio, B. E., Riley, J. T., and Dardik, A. (2002). Cells in focus: endothelial cell. Int. J. Biochem. Cell Biol. 34, 1508-1512. doi: 10.1016/S1357-2725(02)00075-4
    • (2002) Int. J. Biochem. Cell Biol , vol.34 , pp. 1508-1512
    • Sumpio, B.E.1    Riley, J.T.2    Dardik, A.3
  • 102
    • 84930345994 scopus 로고    scopus 로고
    • Isolation of extracellular vesicles: determining the correct approach (Review)
    • Szatanek, R., Baran, J., Siedlar, M., and Baj-Krzyworzeka, M. (2015). Isolation of extracellular vesicles: determining the correct approach (Review). Int. J. Mol. Med. 36, 11-17. doi: 10.3892/ijmm.2015.2194
    • (2015) Int. J. Mol. Med , vol.36 , pp. 11-17
    • Szatanek, R.1    Baran, J.2    Siedlar, M.3    Baj-Krzyworzeka, M.4
  • 103
    • 33846870603 scopus 로고    scopus 로고
    • Antioxidative treatment inhibits the release of thrombogenic tissue factor from irradiation-and cytokine-induced endothelial cells
    • Szotowski, B., Antoniak, S., Goldin-Lang, P., Tran, Q.-V., Pels, K., Rosenthal, P., et al. (2007). Antioxidative treatment inhibits the release of thrombogenic tissue factor from irradiation-and cytokine-induced endothelial cells. Cardiovasc. Res. 73, 806-812. doi: 10.1016/j.cardiores.2006.12.018
    • (2007) Cardiovasc. Res , vol.73 , pp. 806-812
    • Szotowski, B.1    Antoniak, S.2    Goldin-Lang, P.3    Tran, Q.-V.4    Pels, K.5    Rosenthal, P.6
  • 104
    • 0036172425 scopus 로고    scopus 로고
    • Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicle-associated components by endothelial cells
    • Taraboletti, G., D'Ascenzo, S., Borsotti, P., Giavazzi, R., Pavan, A., and Dolo, V. (2002). Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicle-associated components by endothelial cells. Am. J. Pathol. 160, 673-680. doi: 10.1016/S0002-9440(10)64887-0
    • (2002) Am. J. Pathol , vol.160 , pp. 673-680
    • Taraboletti, G.1    D'Ascenzo, S.2    Borsotti, P.3    Giavazzi, R.4    Pavan, A.5    Dolo, V.6
  • 105
    • 84858037808 scopus 로고    scopus 로고
    • Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes
    • Tauro, B. J., Greening, D. W., Mathias, R. A., Ji, H., Mathivanan, S., Scott, A. M., et al. (2012). Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Methods San Diego Calif 56, 293-304. doi: 10.1016/j.ymeth.2012.01.002
    • (2012) Methods San Diego Calif , vol.56 , pp. 293-304
    • Tauro, B.J.1    Greening, D.W.2    Mathias, R.A.3    Ji, H.4    Mathivanan, S.5    Scott, A.M.6
  • 106
    • 0036906477 scopus 로고    scopus 로고
    • Indirect activation of naïve CD4+ T cells by dendritic cell-derived exosomes
    • Théry, C., Duban, L., Segura, E., Véron, P., Lantz, O., and Amigorena, S. (2002). Indirect activation of naïve CD4+ T cells by dendritic cell-derived exosomes. Nat. Immunol. 3, 1156-1162. doi: 10.1038/ni854
    • (2002) Nat. Immunol , vol.3 , pp. 1156-1162
    • Théry, C.1    Duban, L.2    Segura, E.3    Véron, P.4    Lantz, O.5    Amigorena, S.6
  • 108
    • 84938519097 scopus 로고    scopus 로고
    • Intermittent hypoxia impairs endothelial function in early preatherosclerosis
    • Tuleta, I., França, C. N., Wenzel, D., Fleischmann, B., Nickenig, G., Werner, N., et al. (2015). Intermittent hypoxia impairs endothelial function in early preatherosclerosis. Adv. Exp. Med. Biol. 858, 1-7. doi: 10.1007/5584_2015_114
    • (2015) Adv. Exp. Med. Biol , vol.858 , pp. 1-7
    • Tuleta, I.1    França, C.N.2    Wenzel, D.3    Fleischmann, B.4    Nickenig, G.5    Werner, N.6
  • 109
    • 84879419464 scopus 로고    scopus 로고
    • Leukemia cell to endothelial cell communication via exosomal miRNAs
    • Umezu, T., Ohyashiki, K., Kuroda, M., and Ohyashiki, J. H. (2013). Leukemia cell to endothelial cell communication via exosomal miRNAs. Oncogene 32, 2747-2755. doi: 10.1038/onc.2012.295
    • (2013) Oncogene , vol.32 , pp. 2747-2755
    • Umezu, T.1    Ohyashiki, K.2    Kuroda, M.3    Ohyashiki, J.H.4
  • 110
    • 84924973691 scopus 로고    scopus 로고
    • Extracellular vesicles from bone marrow mesenchymal stem/stromal cells transport tumor regulatory microRNA, proteins, and metabolites
    • Vallabhaneni, K. C., Penfornis, P., Dhule, S., Guillonneau, F., Adams, K. V., Mo, Y. Y., et al. (2015). Extracellular vesicles from bone marrow mesenchymal stem/stromal cells transport tumor regulatory microRNA, proteins, and metabolites. Oncotarget 6, 4953-4967. doi: 10.18632/oncotarget.3211
    • (2015) Oncotarget , vol.6 , pp. 4953-4967
    • Vallabhaneni, K.C.1    Penfornis, P.2    Dhule, S.3    Guillonneau, F.4    Adams, K.V.5    Mo, Y.Y.6
  • 111
    • 84930483835 scopus 로고    scopus 로고
    • Classification, functions, and clinical relevance of extracellular vesicles
    • van der Pol, E., Boing, A. N., Harrison, P., Sturk, A., and Nieuwland, R. (2012). Classification, functions, and clinical relevance of extracellular vesicles. Pharmacol. Rev. 64, 676-705. doi: 10.1124/pr.112.005983
    • (2012) Pharmacol. Rev , vol.64 , pp. 676-705
    • van der Pol, E.1    Boing, A.N.2    Harrison, P.3    Sturk, A.4    Nieuwland, R.5
  • 112
    • 85014336174 scopus 로고    scopus 로고
    • EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research
    • Van Deun, J., Mestdagh, P., Agostinis, P., Akay, ö., Anand, S., Anckaert, J., et al. (2017). EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research. Nat. Methods 14, 228-232. doi: 10.1038/nmeth.4185
    • (2017) Nat. Methods , vol.14 , pp. 228-232
    • Van Deun, J.1    Mestdagh, P.2    Agostinis, P.3    Akay, Ö.4    Anand, S.5    Anckaert, J.6
  • 113
    • 85015684168 scopus 로고    scopus 로고
    • The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling
    • Van Deun, J., Mestdagh, P., Sormunen, R., Cocquyt, V., Vermaelen, K., Vandesompele, J., et al. (2014). The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling. J. Extracell. Vesicles 3:24858. doi: 10.3402/jev.v3.24858
    • (2014) J. Extracell. Vesicles , vol.3 , pp. 24858
    • Van Deun, J.1    Mestdagh, P.2    Sormunen, R.3    Cocquyt, V.4    Vermaelen, K.5    Vandesompele, J.6
  • 114
    • 77953420430 scopus 로고    scopus 로고
    • Hypoxia mediated release of endothelial microparticles and increased association of S100A12 with circulating neutrophils
    • Vince, R. V., Chrismas, B., Midgley, A. W., McNaughton, L. R., and Madden, L. A. (2009). Hypoxia mediated release of endothelial microparticles and increased association of S100A12 with circulating neutrophils. Oxid. Med. Cell. Longev. 2, 2-6. doi: 10.4161/oxim.2.1.7611
    • (2009) Oxid. Med. Cell. Longev , vol.2 , pp. 2-6
    • Vince, R.V.1    Chrismas, B.2    Midgley, A.W.3    McNaughton, L.R.4    Madden, L.A.5
  • 115
    • 84879831932 scopus 로고    scopus 로고
    • Shear stress regulates endothelial microparticle release
    • Vion, A.-C., Ramkhelawon, B., Loyer, X., Chironi, G., Devue, C., Loirand, G., et al. (2013). Shear stress regulates endothelial microparticle release. Circ. Res. 112, 1323-1333. doi: 10.1161/CIRCRESAHA.112.300818
    • (2013) Circ. Res , vol.112 , pp. 1323-1333
    • Vion, A.-C.1    Ramkhelawon, B.2    Loyer, X.3    Chironi, G.4    Devue, C.5    Loirand, G.6
  • 116
    • 34247092528 scopus 로고    scopus 로고
    • C-reactive protein-induced endothelial microparticle generation in HUVECs is related to BH4-dependent no formation
    • Wang, J.-M., Wang, Y., Huang, J.-Y., Yang, Z., Chen, L., Wang, L.-C., et al. (2007). C-reactive protein-induced endothelial microparticle generation in HUVECs is related to BH4-dependent no formation. J. Vasc. Res. 44, 241-248. doi: 10.1159/000100558
    • (2007) J. Vasc. Res , vol.44 , pp. 241-248
    • Wang, J.-M.1    Wang, Y.2    Huang, J.-Y.3    Yang, Z.4    Chen, L.5    Wang, L.-C.6
  • 117
    • 85017391075 scopus 로고    scopus 로고
    • Enhanced cardioprotection by human endometrium mesenchymal stem cells driven by exosomal MicroRNA-21: superiority of endometrium mesenchymal stem cells
    • Wang, K., Jiang, Z., Webster, K. A., Chen, J., Hu, H., Zhou, Y., et al. (2017). Enhanced cardioprotection by human endometrium mesenchymal stem cells driven by exosomal MicroRNA-21: superiority of endometrium mesenchymal stem cells. Stem Cells Transl. Med. 6, 209-222. doi: 10.5966/sctm.2015-0386
    • (2017) Stem Cells Transl. Med , vol.6 , pp. 209-222
    • Wang, K.1    Jiang, Z.2    Webster, K.A.3    Chen, J.4    Hu, H.5    Zhou, Y.6
  • 118
    • 84986626342 scopus 로고    scopus 로고
    • Vesicular Galectin-3 levels decrease with donor age and contribute to the reduced osteo-inductive potential of human plasma derived extracellular vesicles
    • Weilner, S., Keider, V., Winter, M., Harreither, E., Salzer, B., Weiss, F., et al. (2016a). Vesicular Galectin-3 levels decrease with donor age and contribute to the reduced osteo-inductive potential of human plasma derived extracellular vesicles. Aging 8, 16-33. doi: 10.18632/aging.100865
    • (2016) Aging , vol.8 , pp. 16-33
    • Weilner, S.1    Keider, V.2    Winter, M.3    Harreither, E.4    Salzer, B.5    Weiss, F.6
  • 119
    • 84879024861 scopus 로고    scopus 로고
    • Secretion of microvesicular miRNAs in cellular and organismal aging
    • Weilner, S., Schraml, E., Redl, H., Grillari-Voglauer, R., and Grillari, J. (2013). Secretion of microvesicular miRNAs in cellular and organismal aging. Exp. Gerontol. 48, 626-633. doi: 10.1016/j.exger.2012.11.017
    • (2013) Exp. Gerontol , vol.48 , pp. 626-633
    • Weilner, S.1    Schraml, E.2    Redl, H.3    Grillari-Voglauer, R.4    Grillari, J.5
  • 120
    • 84977644852 scopus 로고    scopus 로고
    • Secreted microvesicular miR-31 inhibits osteogenic differentiation of mesenchymal stem cells
    • Weilner, S., Schraml, E., Wieser, M., Messner, P., Schneider, K., Wassermann, K., et al. (2016b). Secreted microvesicular miR-31 inhibits osteogenic differentiation of mesenchymal stem cells. Aging Cell 15, 744-754. doi: 10.1111/acel.12484
    • (2016) Aging Cell , vol.15 , pp. 744-754
    • Weilner, S.1    Schraml, E.2    Wieser, M.3    Messner, P.4    Schneider, K.5    Wassermann, K.6
  • 121
    • 85013178173 scopus 로고    scopus 로고
    • Extracellular vesicles isolation and their biomarker potential: are we ready for testing?
    • Whiteside, T. L. (2017). Extracellular vesicles isolation and their biomarker potential: are we ready for testing? Ann. Transl. Med. 5:54. doi: 10.21037/atm.2017.01.62
    • (2017) Ann. Transl. Med , vol.5 , pp. 54
    • Whiteside, T.L.1
  • 122
    • 85013222187 scopus 로고    scopus 로고
    • Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
    • Witwer, K. W., Buzás, E. I., Bemis, L. T., Bora, A., Lässer, C., Lötvall, J., et al. (2013). Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J. Extracell. Vesicles 2:20360. doi: 10.3402/jev.v2i0.20360
    • (2013) J. Extracell. Vesicles , vol.2 , pp. 20360
    • Witwer, K.W.1    Buzás, E.I.2    Bemis, L.T.3    Bora, A.4    Lässer, C.5    Lötvall, J.6
  • 123
    • 84978370194 scopus 로고    scopus 로고
    • Exosomes from high glucose-treated glomerular endothelial cells activate mesangial cells to promote renal fibrosis
    • Wu, X., Gao, Y., Cui, F., and Zhang, N. (2016). Exosomes from high glucose-treated glomerular endothelial cells activate mesangial cells to promote renal fibrosis. Biol. Open 5, 484-491. doi: 10.1242/bio.015990
    • (2016) Biol. Open , vol.5 , pp. 484-491
    • Wu, X.1    Gao, Y.2    Cui, F.3    Zhang, N.4
  • 124
    • 68549128599 scopus 로고    scopus 로고
    • Lung cancer secreted microvesicles: underappreciated modulators of microenvironment in expanding tumors
    • Wysoczynski, M., and Ratajczak, M. Z. (2009). Lung cancer secreted microvesicles: underappreciated modulators of microenvironment in expanding tumors. Int. J. Cancer 125, 1595-1603. doi: 10.1002/ijc.24479
    • (2009) Int. J. Cancer , vol.125 , pp. 1595-1603
    • Wysoczynski, M.1    Ratajczak, M.Z.2
  • 125
    • 84923368860 scopus 로고    scopus 로고
    • Inflammation-induced endothelial cell-derived extracellular vesicles modulate the cellular status of pericytes
    • Yamamoto, S., Niida, S., Azuma, E., Yanagibashi, T., Muramatsu, M., Huang, T. T., et al. (2015). Inflammation-induced endothelial cell-derived extracellular vesicles modulate the cellular status of pericytes. Sci. Rep. 5:8505. doi: 10.1038/srep08505
    • (2015) Sci. Rep , vol.5 , pp. 8505
    • Yamamoto, S.1    Niida, S.2    Azuma, E.3    Yanagibashi, T.4    Muramatsu, M.5    Huang, T.T.6
  • 127
    • 84930424126 scopus 로고    scopus 로고
    • Human umbilical cord mesenchymal stem cell exosomes enhance angiogenesis through the Wnt4/ß-catenin pathway
    • Zhang, B., Wu, X., Zhang, X., Sun, Y., Yan, Y., Shi, H., et al. (2015). Human umbilical cord mesenchymal stem cell exosomes enhance angiogenesis through the Wnt4/ß-catenin pathway. Stem Cells Transl. Med. 4, 513-522. doi: 10.5966/sctm.2014-0267
    • (2015) Stem Cells Transl. Med , vol.4 , pp. 513-522
    • Zhang, B.1    Wu, X.2    Zhang, X.3    Sun, Y.4    Yan, Y.5    Shi, H.6
  • 128
    • 77954257796 scopus 로고    scopus 로고
    • Secreted monocytic miR-150 enhances targeted endothelial cell migration
    • Zhang, Y., Liu, D., Chen, X., Li, J., Li, L., Bian, Z., et al. (2010). Secreted monocytic miR-150 enhances targeted endothelial cell migration. Mol. Cell 39, 133-144. doi: 10.1016/j.molcel.2010.06.010
    • (2010) Mol. Cell , vol.39 , pp. 133-144
    • Zhang, Y.1    Liu, D.2    Chen, X.3    Li, J.4    Li, L.5    Bian, Z.6
  • 129
    • 85009423895 scopus 로고    scopus 로고
    • Exosomes derived from human pulmonary artery endothelial cells shift the balance between proliferation and apoptosis of smooth muscle cells
    • Zhao, L., Luo, H., Li, X., Li, T., He, J., Qi, Q., et al. (2017). Exosomes derived from human pulmonary artery endothelial cells shift the balance between proliferation and apoptosis of smooth muscle cells. Cardiology 137, 43-53. doi: 10.1159/000453544
    • (2017) Cardiology , vol.137 , pp. 43-53
    • Zhao, L.1    Luo, H.2    Li, X.3    Li, T.4    He, J.5    Qi, Q.6
  • 130
    • 81955167406 scopus 로고    scopus 로고
    • Exosomes derived from human bone marrow mesenchymal stem cells promote tumor growth in vivo
    • Zhu, W., Huang, L., Li, Y., Zhang, X., Gu, J., Yan, Y., et al. (2012). Exosomes derived from human bone marrow mesenchymal stem cells promote tumor growth in vivo. Cancer Lett. 315, 28-37. doi: 10.1016/j.canlet.2011.10.002
    • (2012) Cancer Lett , vol.315 , pp. 28-37
    • Zhu, W.1    Huang, L.2    Li, Y.3    Zhang, X.4    Gu, J.5    Yan, Y.6
  • 131
    • 84866093563 scopus 로고    scopus 로고
    • Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway
    • Zhuang, G., Wu, X., Jiang, Z., Kasman, I., Yao, J., Guan, Y., et al. (2012). Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway. EMBO J. 31, 3513-3523. doi: 10.1038/emboj.2012.183
    • (2012) EMBO J , vol.31 , pp. 3513-3523
    • Zhuang, G.1    Wu, X.2    Jiang, Z.3    Kasman, I.4    Yao, J.5    Guan, Y.6


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