-
1
-
-
84892868891
-
The microenvironment in chronic lymphocytic leukemia (CLL) and other B cell malignancies: Insight into disease biology and new targeted therapies
-
Burger JA, Gribben JG. The microenvironment in chronic lymphocytic leukemia (CLL) and other B cell malignancies: insight into disease biology and new targeted therapies. Semin Cancer Biol. 2014;24:71-81.
-
(2014)
Semin Cancer Biol.
, vol.24
, pp. 71-81
-
-
Burger, J.A.1
Gribben, J.G.2
-
2
-
-
84875802229
-
Biology of chronic lymphocytic leukemia in different microenvironments: Clinical and therapeutic implications
-
Herishanu Y, Katz BZ, Lipsky A, Wiestner A. Biology of chronic lymphocytic leukemia in different microenvironments: clinical and therapeutic implications. Hematol Oncol Clin North Am. 2013;27(2):173-206.
-
(2013)
Hematol Oncol Clin North Am.
, vol.27
, Issue.2
, pp. 173-206
-
-
Herishanu, Y.1
Katz, B.Z.2
Lipsky, A.3
Wiestner, A.4
-
3
-
-
84897901864
-
Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL)
-
Woyach JA, Bojnik E, Ruppert AS, et al. Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL). Blood. 2014;123(8):1207-1213.
-
(2014)
Blood
, vol.123
, Issue.8
, pp. 1207-1213
-
-
Woyach, J.A.1
Bojnik, E.2
Ruppert, A.S.3
-
4
-
-
84888440844
-
B cell receptor signaling in chronic lymphocytic leukemia
-
Burger JA, Chiorazzi N. B cell receptor signaling in chronic lymphocytic leukemia. Trends Immunol. 2013;34(12):592-601.
-
(2013)
Trends Immunol.
, vol.34
, Issue.12
, pp. 592-601
-
-
Burger, J.A.1
Chiorazzi, N.2
-
5
-
-
0033567968
-
Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
-
Damle RN, Wasil T, Fais F, et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood. 1999;94(6):1840-1847.
-
(1999)
Blood
, vol.94
, Issue.6
, pp. 1840-1847
-
-
Damle, R.N.1
Wasil, T.2
Fais, F.3
-
6
-
-
0033567907
-
Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
-
Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood. 1999;94(6): 1848-1854.
-
(1999)
Blood
, vol.94
, Issue.6
, pp. 1848-1854
-
-
Hamblin, T.J.1
Davis, Z.2
Gardiner, A.3
Oscier, D.G.4
Stevenson, F.K.5
-
7
-
-
0035803371
-
Relation of gene expression phenotype to immunoglobulin mutation genotype in B cellchronic lymphocytic leukemia
-
Rosenwald A, Alizadeh AA, Widhopf G, et al. Relation of gene expression phenotype to immunoglobulin mutation genotype in B cellchronic lymphocytic leukemia. J Exp Med. 2001; 194(11):1639-1647.
-
(2001)
J Exp Med.
, vol.194
, Issue.11
, pp. 1639-1647
-
-
Rosenwald, A.1
Alizadeh, A.A.2
Widhopf, G.3
-
8
-
-
10744222814
-
ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile
-
Wiestner A, Rosenwald A, Barry TS, et al. ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile. Blood. 2003;101(12): 4944-4951.
-
(2003)
Blood
, vol.101
, Issue.12
, pp. 4944-4951
-
-
Wiestner, A.1
Rosenwald, A.2
Barry, T.S.3
-
9
-
-
0037306842
-
Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukemia
-
Lanham S, Hamblin T, Oscier D, Ibbotson R, Stevenson F, Packham G. Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukemia. Blood. 2003;101(3): 1087-1093.
-
(2003)
Blood
, vol.101
, Issue.3
, pp. 1087-1093
-
-
Lanham, S.1
Hamblin, T.2
Oscier, D.3
Ibbotson, R.4
Stevenson, F.5
Packham, G.6
-
10
-
-
84897451152
-
A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor
-
Burke RT, Meadows S, Loriaux MM, et al. A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor. Oncotarget. 2014;5(4):908-915.
-
(2014)
Oncotarget
, vol.5
, Issue.4
, pp. 908-915
-
-
Burke, R.T.1
Meadows, S.2
Loriaux, M.M.3
-
11
-
-
84900484963
-
Leukaemic cells from chronic lymphocytic leukaemia patients undergo apoptosis following microtubule depolymerization and Lyn inhibition by nocodazole
-
Frezzato F, Trimarco V, Martini V, et al. Leukaemic cells from chronic lymphocytic leukaemia patients undergo apoptosis following microtubule depolymerization and Lyn inhibition by nocodazole. Br J Haematol. 2014;165(5): 659-672.
-
(2014)
Br J Haematol.
, vol.165
, Issue.5
, pp. 659-672
-
-
Frezzato, F.1
Trimarco, V.2
Martini, V.3
-
12
-
-
84884523966
-
Ibrutinib in relapsed chronic lymphocytic leukemia
-
Byrd JC, O'Brien S, James DF. Ibrutinib in relapsed chronic lymphocytic leukemia. N Engl J Med. 2013;369(13):1278-1279.
-
(2013)
N Engl J Med.
, vol.369
, Issue.13
, pp. 1278-1279
-
-
Byrd, J.C.1
O'Brien, S.2
James, D.F.3
-
13
-
-
84858590826
-
Accessories to the crime: Functions of cells recruited to the tumormicroenvironment
-
Hanahan D, Coussens LM. Accessories to the crime: functions of cells recruited to the tumormicroenvironment. Cancer Cell. 2012;21(3): 309-322.
-
(2012)
Cancer Cell
, vol.21
, Issue.3
, pp. 309-322
-
-
Hanahan, D.1
Coussens, L.M.2
-
14
-
-
84861116448
-
Tumor microenvironment complexity: Emerging roles in cancer therapy
-
Swartz MA, Iida N, Roberts EW, et al. Tumor microenvironment complexity: emerging roles in cancer therapy. Cancer Res. 2012;72(10): 2473-2480.
-
(2012)
Cancer Res.
, vol.72
, Issue.10
, pp. 2473-2480
-
-
Swartz, M.A.1
Iida, N.2
Roberts, E.W.3
-
15
-
-
84862618600
-
Tumor-derived microvesicles: Shedding light on novel microenvironment modulators and prospective cancer biomarkers
-
D'Souza-Schorey C, Clancy JW. Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers. Genes Dev. 2012;26(12): 1287-1299.
-
(2012)
Genes Dev.
, vol.26
, Issue.12
, pp. 1287-1299
-
-
D'Souza-Schorey, C.1
Clancy, J.W.2
-
16
-
-
84874377202
-
Extracellular vesicles: Exosomes, microvesicles, and friends
-
Raposo G, Stoorvogel W. Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol. 2013;200(4):373-383.
-
(2013)
J Cell Biol.
, vol.200
, Issue.4
, pp. 373-383
-
-
Raposo, G.1
Stoorvogel, W.2
-
17
-
-
84880280703
-
Extracellular vesicles in chronic lymphocytic leukemia
-
Haderk F, Hanna B, Richter K, et al. Extracellular vesicles in chronic lymphocytic leukemia. Leuk Lymphoma. 2013;54(8):1826-1830.
-
(2013)
Leuk Lymphoma
, vol.54
, Issue.8
, pp. 1826-1830
-
-
Haderk, F.1
Hanna, B.2
Richter, K.3
-
18
-
-
85027933779
-
Exosomes: Immune properties and potential clinical implementations
-
Chaput N, Théry C. Exosomes: immune properties and potential clinical implementations. Semin Immunopathol. 2011;33(5):419-440.
-
(2011)
Semin Immunopathol.
, vol.33
, Issue.5
, pp. 419-440
-
-
Chaput, N.1
Théry, C.2
-
19
-
-
77950352713
-
Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: Implications for disease progression
-
Ghosh AK, Secreto CR, Knox TR, Ding W, Mukhopadhyay D, Kay NE. Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression. Blood. 2010;115(9):1755-1764.
-
(2010)
Blood
, vol.115
, Issue.9
, pp. 1755-1764
-
-
Ghosh, A.K.1
Secreto, C.R.2
Knox, T.R.3
Ding, W.4
Mukhopadhyay, D.5
Kay, N.E.6
-
20
-
-
79951470770
-
The novel receptor tyrosine kinase Axl is constitutively active in B-cell chronic lymphocytic leukemia and acts as a docking site of nonreceptor kinases:implications for therapy
-
Ghosh AK, Secreto C, Boysen J, et al. The novel receptor tyrosine kinase Axl is constitutively active in B-cell chronic lymphocytic leukemia and acts as a docking site of nonreceptor kinases:implications for therapy. Blood. 2011;117(6): 1928-1937.
-
(2011)
Blood
, vol.117
, Issue.6
, pp. 1928-1937
-
-
Ghosh, A.K.1
Secreto, C.2
Boysen, J.3
-
21
-
-
84886367490
-
Prognostic value of MIR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia
-
Ferrajoli A, Shanafelt TD, Ivan C, et al. Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia. Blood. 2013;122(11): 1891-1899.
-
(2013)
Blood
, vol.122
, Issue.11
, pp. 1891-1899
-
-
Ferrajoli, A.1
Shanafelt, T.D.2
Ivan, C.3
-
22
-
-
79955582317
-
MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia
-
Moussay E, Wang K, Cho JH, et al. MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia. Proc Natl Acad Sci USA. 2011;108(16):6573-6578.
-
(2011)
Proc Natl Acad Sci USA.
, vol.108
, Issue.16
, pp. 6573-6578
-
-
Moussay, E.1
Wang, K.2
Cho, J.H.3
-
23
-
-
68849129712
-
Membrane vesicles as conveyors of immune responses
-
Théry C, Ostrowski M, Segura E. Membrane vesicles as conveyors of immune responses. Nat Rev Immunol. 2009;9(8):581-593.
-
(2009)
Nat Rev Immunol.
, vol.9
, Issue.8
, pp. 581-593
-
-
Théry, C.1
Ostrowski, M.2
Segura, E.3
-
24
-
-
0022201056
-
Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes
-
Pan BT, Teng K, Wu C, Adam M, Johnstone RM. Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes. J Cell Biol. 1985;101(3): 942-948.
-
(1985)
J Cell Biol.
, vol.101
, Issue.3
, pp. 942-948
-
-
Pan, B.T.1
Teng, K.2
Wu, C.3
Adam, M.4
Johnstone, R.M.5
-
25
-
-
0033485648
-
Activated platelets release two types of membrane vesicles: Microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules
-
Heijnen HF, Schiel AE, Fijnheer R, Geuze HJ, Sixma JJ. Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. Blood. 1999;94(11):3791-3799.
-
(1999)
Blood
, vol.94
, Issue.11
, pp. 3791-3799
-
-
Heijnen, H.F.1
Schiel, A.E.2
Fijnheer, R.3
Geuze, H.J.4
Sixma, J.J.5
-
26
-
-
43249109372
-
Isolation and characterization of exosomes from cell culture supernatants and biological fluids
-
1-3.22.29
-
Thery C, Amigorena S, Raposo G, et al. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol. 2006:3.22.1-3.22.29.
-
(2006)
Curr Protoc Cell Biol.
, vol.3
, pp. 22
-
-
Thery, C.1
Amigorena, S.2
Raposo, G.3
-
27
-
-
0037490207
-
Exosome release is regulated by a calciumdependent mechanism in K562 cells
-
Savina A, Furlán M, Vidal M, Colombo MI. Exosome release is regulated by a calciumdependent mechanism in K562 cells. J Biol Chem. 2003;278(22):20083-20090.
-
(2003)
J Biol Chem.
, vol.278
, Issue.22
, pp. 20083-20090
-
-
Savina, A.1
Furlán, M.2
Vidal, M.3
Colombo, M.I.4
-
28
-
-
81055157988
-
Exosome secretion: Molecular mechanisms and roles in immune responses
-
Bobrie A, Colombo M, Raposo G, Théry C. Exosome secretion: molecular mechanisms and roles in immune responses. Traffic. 2011;12(12): 1659-1668.
-
(2011)
Traffic
, vol.12
, Issue.12
, pp. 1659-1668
-
-
Bobrie, A.1
Colombo, M.2
Raposo, G.3
Théry, C.4
-
29
-
-
84862007577
-
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
-
Peinado H, Aleeč;ković M, Lavotshkin S, et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med. 2012;18(6): 883-891.
-
(2012)
Nat Med.
, Issue.18
, pp. 883-891
-
-
Peinado, H.1
Aleeč Ković, M.2
Lavotshkin, S.3
-
30
-
-
84864503916
-
MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
-
Fabbri M, Paone A, Calore F, et al. MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response. Proc Natl Acad Sci USA. 2012;109(31):E2110-E2116.
-
(2012)
Proc Natl Acad Sci USA.
, vol.109
, Issue.31
, pp. E2110-E2116
-
-
Fabbri, M.1
Paone, A.2
Calore, F.3
-
31
-
-
84905643012
-
Hypoxiainducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
-
Wang T, Gilkes DM, Takano N, et al. Hypoxiainducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis. Proc Natl Acad Sci USA. 2014;111(31):E3234-E3242.
-
(2014)
Proc Natl Acad Sci USA.
, vol.111
, Issue.31
, pp. E3234-E3242
-
-
Wang, T.1
Gilkes, D.M.2
Takano, N.3
-
32
-
-
84904868088
-
Bone marrow stromal cell-derived exosomes as communicators in drug resistance in multiple myeloma cells
-
Wang J, Hendrix A, Hernot S, et al. Bone marrow stromal cell-derived exosomes as communicators in drug resistance in multiple myeloma cells. Blood. 2014;124(4):555-566.
-
(2014)
Blood
, vol.124
, Issue.4
, pp. 555-566
-
-
Wang, J.1
Hendrix, A.2
Hernot, S.3
-
33
-
-
84876927914
-
Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
-
Kucharzewska P, Christianson HC, Welch JE, et al. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc Natl Acad Sci USA. 2013; 110(18):7312-7317.
-
(2013)
Proc Natl Acad Sci USA.
, vol.110
, Issue.18
, pp. 7312-7317
-
-
Kucharzewska, P.1
Christianson, H.C.2
Welch, J.E.3
-
34
-
-
76649097628
-
Membraneassociated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells
-
Chalmin F, Ladoire S, Mignot G, et al. Membraneassociated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. J Clin Invest. 2010;120(2): 457-471.
-
(2010)
J Clin Invest.
, vol.120
, Issue.2
, pp. 457-471
-
-
Chalmin, F.1
Ladoire, S.2
Mignot, G.3
-
35
-
-
84871563123
-
Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration
-
Luga V, Zhang L, Viloria-Petit AM, et al. Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration. Cell. 2012;151(7):1542-1556.
-
(2012)
Cell
, vol.151
, Issue.7
, pp. 1542-1556
-
-
Luga, V.1
Zhang, L.2
Viloria-Petit, A.M.3
-
36
-
-
77957195392
-
Exosome release of b-catenin: A novel mechanism that antagonizes Wnt signaling
-
Chairoungdua A, Smith DL, Pochard P, Hull M, Caplan MJ. Exosome release of b-catenin: a novel mechanism that antagonizes Wnt signaling. J Cell Biol. 2010;190(6):1079-1091.
-
(2010)
J Cell Biol.
, vol.190
, Issue.6
, pp. 1079-1091
-
-
Chairoungdua, A.1
Smith, D.L.2
Pochard, P.3
Hull, M.4
Caplan, M.J.5
-
37
-
-
78649958307
-
Cancer exosomes trigger fibroblast to myofibroblast differentiation
-
Webber J, Steadman R, Mason MD, Tabi Z, Clayton A. Cancer exosomes trigger fibroblast to myofibroblast differentiation. Cancer Res. 2010;70(23):9621-9630.
-
(2010)
Cancer Res.
, vol.70
, Issue.23
, pp. 9621-9630
-
-
Webber, J.1
Steadman, R.2
Mason, M.D.3
Tabi, Z.4
Clayton, A.5
-
38
-
-
45149100665
-
International workshop on chronic lymphocytic leukemia. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the international workshop on chronic lymphocytic leukemia updating the national cancer institute-working group 1996
-
Hallek M, Cheson BD, Catovsky D, et al; International Workshop on Chronic Lymphocytic Leukemia. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood. 2008;111(12):5446-5456.
-
(2008)
Guidelines. Blood
, vol.111
, Issue.12
, pp. 5446-5456
-
-
Hallek, M.1
Cheson, B.D.2
Catovsky, D.3
-
39
-
-
84871236598
-
The novel cyclin-dependent kinase inhibitor dinaciclib (SCH727965) promotes apoptosis and abrogates microenvironmental cytokine protection in chronic lymphocytic leukemia cells
-
Johnson AJ, Yeh YY, Smith LL, et al. The novel cyclin-dependent kinase inhibitor dinaciclib (SCH727965) promotes apoptosis and abrogates microenvironmental cytokine protection in chronic lymphocytic leukemia cells. Leukemia. 2012; 26(12):2554-2557.
-
(2012)
Leukemia
, vol.26
, Issue.12
, pp. 2554-2557
-
-
Johnson, A.J.1
Yeh, Y.Y.2
Smith, L.L.3
-
40
-
-
80055118968
-
Sizing and phenotyping of cellular vesicles using nanoparticle tracking analysis
-
Dragovic RA, Gardiner C, Brooks AS, et al. Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis. Nanomedicine (Lond Print). 2011;7(6):780-788.
-
(2011)
Nanomedicine (Lond Print)
, vol.7
, Issue.6
, pp. 780-788
-
-
Dragovic, R.A.1
Gardiner, C.2
Brooks, A.S.3
-
41
-
-
84923281763
-
Up-regulation of CDK9 kinase activity and Mcl-1 stability contributes to the acquired resistance to cyclin-dependent kinase inhibitors in leukemia
-
Yeh YY, Chen R, Hessler J, et al. Up-regulation of CDK9 kinase activity and Mcl-1 stability contributes to the acquired resistance to cyclin-dependent kinase inhibitors in leukemia. Oncotarget. 2015;6(5):2667-2679.
-
(2015)
Oncotarget
, vol.6
, Issue.5
, pp. 2667-2679
-
-
Yeh, Y.Y.1
Chen, R.2
Hessler, J.3
-
42
-
-
0037129827
-
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
-
RESEARCH0034
-
Vandesompele J, De Preter K, Pattyn F, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002;3(7): RESEARCH0034.
-
(2002)
Genome Biol.
, vol.3
, Issue.7
-
-
Vandesompele, J.1
De Preter, K.2
Pattyn, F.3
-
43
-
-
84878771209
-
Gene feature discovery in RNA-seq experiments from multiple sources
-
Ozer HG, Parvin JD, Huang K. DFI: gene feature discovery in RNA-seq experiments from multiple sources. BMC Genomics. 2012;13(Suppl 8):S11.
-
(2012)
BMC Genomics
, vol.13
, pp. S11
-
-
Ozer, H.G.1
Parvin, J.D.2
Dfi, H.K.3
-
44
-
-
84903186936
-
Non-inhibited MIRNAs shape the cellular response to anti-MIR
-
Androsavich JR, Chau BN. Non-inhibited miRNAs shape the cellular response to anti-miR. Nucleic Acids Res. 2014;42(11):6945-6955.
-
(2014)
Nucleic Acids Res.
, vol.42
, Issue.11
, pp. 6945-6955
-
-
Androsavich, J.R.1
Chau, B.N.2
-
45
-
-
84894286325
-
Dynamic impacts of the inhibition of the molecular chaperone Hsp90 on the T-cell proteome have implications for anticancer therapy
-
Fierro-Monti I, Echeverria P, Racle J, Hernandez C, Picard D, Quadroni M. Dynamic impacts of the inhibition of the molecular chaperone Hsp90 on the T-cell proteome have implications for anticancer therapy. PLoS ONE. 2013;8(11):e80425.
-
(2013)
PLoS ONE
, vol.8
, Issue.11
, pp. e80425
-
-
Fierro-Monti, I.1
Echeverria, P.2
Racle, J.3
Hernandez, C.4
Picard, D.5
Quadroni, M.6
-
46
-
-
0036533633
-
TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex
-
Blanchard N, Lankar D, Faure F, et al. TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. J Immunol. 2002;168(7):3235-3241.
-
(2002)
J Immunol.
, vol.168
, Issue.7
, pp. 3235-3241
-
-
Blanchard, N.1
Lankar, D.2
Faure, F.3
-
47
-
-
0035166047
-
Analysis of antigen presenting cell derived exosomes, based on immuno-magnetic isolation and flow cytometry
-
Clayton A, Court J, Navabi H, et al. Analysis of antigen presenting cell derived exosomes, based on immuno-magnetic isolation and flow cytometry. J Immunol Methods. 2001;247(1-2):163-174.
-
(2001)
J Immunol Methods
, vol.247
, Issue.1-2
, pp. 163-174
-
-
Clayton, A.1
Court, J.2
Navabi, H.3
-
48
-
-
84866152581
-
Immune surveillance properties of human NK cell-derived exosomes
-
Lugini L, Cecchetti S, Huber V, et al. Immune surveillance properties of human NK cell-derived exosomes. J Immunol. 2012;189(6):2833-2842.
-
(2012)
J Immunol.
, vol.189
, Issue.6
, pp. 2833-2842
-
-
Lugini, L.1
Cecchetti, S.2
Huber, V.3
-
49
-
-
0040089526
-
Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73
-
Théry C, Regnault A, Garin J, et al. Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73. J Cell Biol. 1999;147(3): 599-610.
-
(1999)
J Cell Biol.
, vol.147
, Issue.3
, pp. 599-610
-
-
Théry, C.1
Regnault, A.2
Garin, J.3
Et, A.4
-
50
-
-
20244373139
-
Tumorderived exosomes are a source of shared tumor rejection antigens for CTL cross-priming
-
Wolfers J, Lozier A, Raposo G, et al. Tumorderived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Nat Med. 2001;7(3):297-303.
-
(2001)
Nat Med.
, vol.7
, Issue.3
, pp. 297-303
-
-
Wolfers, J.1
Lozier, A.2
Raposo, G.3
-
51
-
-
84892607130
-
Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion
-
Atay S, Banskota S, Crow J, Sethi G, Rink L, Godwin AK. Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion. Proc Natl Acad Sci USA. 2014;111(2): 711-716.
-
(2014)
Proc Natl Acad Sci USA.
, vol.111
, Issue.2
, pp. 711-716
-
-
Atay, S.1
Banskota, S.2
Crow, J.3
Sethi, G.4
Rink, L.5
Godwin, A.K.6
-
52
-
-
50949130683
-
Induction of exosome release in primary B cells stimulated via CD40 and the IL-4 receptor
-
Saunderson SC, Schuberth PC, Dunn AC, et al. Induction of exosome release in primary B cells stimulated via CD40 and the IL-4 receptor. J Immunol. 2008;180(12):8146-8152.
-
(2008)
J Immunol.
, vol.180
, Issue.12
, pp. 8146-8152
-
-
Saunderson, S.C.1
Schuberth, P.C.2
Dunn, A.C.3
-
53
-
-
22044447897
-
ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming
-
Segura E, Nicco C, Lombard B, et al. ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming. Blood. 2005;106(1): 216-223.
-
(2005)
Blood
, vol.106
, Issue.1
, pp. 216-223
-
-
Segura, E.1
Nicco, C.2
Lombard, B.3
-
54
-
-
84866152172
-
Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling
-
Dühren-von Minden M, Übelhart R, Schneider D, et al. Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling. Nature. 2012;489(7415):309-312.
-
(2012)
Nature
, vol.489
, Issue.7415
, pp. 309-312
-
-
Dühren-Von Minden, M.1
Übelhart, R.2
Schneider, D.3
-
55
-
-
79959404661
-
Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
-
Herman SE, Gordon AL, Hertlein E, et al. Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765. Blood. 2011;117(23):6287-6296.
-
(2011)
Blood
, vol.117
, Issue.23
, pp. 6287-6296
-
-
Herman, S.E.1
Gordon, A.L.2
Hertlein, E.3
-
56
-
-
84879748062
-
Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia
-
Byrd JC, Furman RR, Coutre SE, et al. Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia. N Engl J Med. 2013;369(1):32-42.
-
(2013)
N Engl J Med.
, vol.369
, Issue.1
, pp. 32-42
-
-
Byrd, J.C.1
Furman, R.R.2
Coutre, S.E.3
-
57
-
-
84872534918
-
RNA trafficking by acute myelogenous leukemia exosomes
-
Huan J, Hornick NI, Shurtleff MJ, et al. RNA trafficking by acute myelogenous leukemia exosomes. Cancer Res. 2013;73(2):918-929.
-
(2013)
Cancer Res.
, vol.73
, Issue.2
, pp. 918-929
-
-
Huan, J.1
Hornick, N.I.2
Shurtleff, M.J.3
-
58
-
-
34249302620
-
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
-
Valadi H, Ekström K, Bossios A, Sjöstrand M, Lee JJ, Lötvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007;9(6):654-659.
-
(2007)
Nat Cell Biol.
, vol.9
, Issue.6
, pp. 654-659
-
-
Valadi, H.1
Ekström, K.2
Bossios, A.3
Sjöstrand, M.4
Lee, J.J.5
Lötvall, J.O.6
-
59
-
-
27244434788
-
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
-
Calin GA, Ferracin M, Cimmino A, et al. A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med. 2005;353(17):1793-1801.
-
(2005)
N Engl J Med.
, vol.353
, Issue.17
, pp. 1793-1801
-
-
Calin, G.A.1
Ferracin, M.2
Cimmino, A.3
-
60
-
-
25444520537
-
MIR-15 and MIR-16 induce apoptosis by targeting BCL2
-
Cimmino A, Calin GA, Fabbri M, et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA. 2005;102(39):13944-13949.
-
(2005)
Proc Natl Acad Sci USA.
, vol.102
, Issue.39
, pp. 13944-13949
-
-
Cimmino, A.1
Calin, G.A.2
Fabbri, M.3
-
61
-
-
84904887947
-
MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia
-
Cui B, Chen L, Zhang S, et al. MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia. Blood. 2014;124(4): 546-554.
-
(2014)
Blood
, vol.124
, Issue.4
, pp. 546-554
-
-
Cui, B.1
Chen, L.2
Zhang, S.3
-
62
-
-
70449713652
-
Karyotype-specific microRNA signature in chronic lymphocytic leukemia
-
Visone R, Rassenti LZ, Veronese A, et al. Karyotype-specific microRNA signature in chronic lymphocytic leukemia. Blood. 2009;114(18): 3872-3879.
-
(2009)
Blood
, vol.114
, Issue.18
, pp. 3872-3879
-
-
Visone, R.1
Rassenti, L.Z.2
Veronese, A.3
-
63
-
-
67149147424
-
MicroRNA-29c and microRNA-223 downregulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification
-
Stamatopoulos B, Meuleman N, Haibe-Kains B, et al. microRNA-29c and microRNA-223 downregulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification. Blood. 2009;113(21):5237-5245.
-
(2009)
Blood
, vol.113
, Issue.21
, pp. 5237-5245
-
-
Stamatopoulos, B.1
Meuleman, N.2
Haibe-Kains, B.3
-
64
-
-
84903977667
-
MIR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1
-
Mraz M, Chen L, Rassenti LZ, et al. miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1. Blood. 2014;124(1):84-95.
-
(2014)
Blood
, vol.124
, Issue.1
, pp. 84-95
-
-
Mraz, M.1
Chen, L.2
Rassenti, L.Z.3
-
65
-
-
42449141513
-
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia
-
Garzon R, Volinia S, Liu CG, et al. MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia. Blood. 2008;111(6):3183-3189.
-
(2008)
Blood
, vol.111
, Issue.6
, pp. 3183-3189
-
-
Garzon, R.1
Volinia, S.2
Liu, C.G.3
-
66
-
-
84898000670
-
Increased microRNA-630 expression in gastric cancer is associated with poor overall survival
-
Chu D, Zhao Z, Li Y, et al. Increased microRNA-630 expression in gastric cancer is associated with poor overall survival. PLoS ONE. 2014;9(3): e90526.
-
(2014)
PLoS ONE
, vol.9
, Issue.3
, pp. e90526
-
-
Chu, D.1
Zhao, Z.2
Li, Y.3
-
67
-
-
84923025327
-
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1
-
Ma X, Li C, Sun L, et al. Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1. Nat Commun. 2014;5:5212.
-
(2014)
Nat Commun.
, vol.5
, pp. 5212
-
-
Ma, X.1
Li, C.2
Sun, L.3
-
68
-
-
77950839553
-
Children's cancer and leukaemia group malignant germ cell tumors display common microRNA profiles resulting in global changes in expression of messenger RNA targets
-
Palmer RD, Murray MJ, Saini HK, et al; Children's Cancer and Leukaemia Group. Malignant germ cell tumors display common microRNA profiles resulting in global changes in expression of messenger RNA targets. Cancer Res. 2010;70(7): 2911-2923.
-
(2010)
Cancer Res.
, vol.70
, Issue.7
, pp. 2911-2923
-
-
Palmer, R.D.1
Murray, M.J.2
Saini, H.K.3
-
69
-
-
84859129420
-
Mirna expression profiles identify drivers in colorectal and pancreatic cancers
-
Piepoli A, Tavano F, Copetti M, et al. Mirna expression profiles identify drivers in colorectal and pancreatic cancers. PLoS ONE. 2012;7(3): e33663.
-
(2012)
PLoS ONE
, vol.7
, Issue.3
, pp. e33663
-
-
Piepoli, A.1
Tavano, F.2
Copetti, M.3
-
70
-
-
41449093809
-
B-cell receptor activation induces BIC/MIR-155 expression through a conserved AP-1 element
-
Yin Q, Wang X, McBride J, Fewell C, Flemington E. B-cell receptor activation induces BIC/miR-155 expression through a conserved AP-1 element. J Biol Chem. 2008;283(5):2654-2662.
-
(2008)
J Biol Chem.
, vol.283
, Issue.5
, pp. 2654-2662
-
-
Yin, Q.1
Wang, X.2
McBride, J.3
Fewell, C.4
Flemington, E.5
-
71
-
-
84983462314
-
Aberrant PD-L1 expression in CLL as a result of adaptive immune resistance mediated by tumor-secreted circulating miRNA binding to Toll-like receptor 7 [abstract]
-
Abstract 716
-
McClanahan F, Calore F, Zanesi N, et al. Aberrant PD-L1 expression in CLL as a result of adaptive immune resistance mediated by tumor-secreted circulating miRNA binding to Toll-like receptor 7 [abstract]. Blood. 2014; 124(21). Abstract 716.
-
(2014)
Blood
, vol.124
, Issue.21
-
-
McClanahan, F.1
Calore, F.2
Zanesi, N.3
|