Alterations in acute myeloid leukaemia bone marrow stromal cell exosome content coincide with gains in tyrosine kinase inhibitor resistance

British Journal of Haematology

Volumn 172, Issue 6, 2016, Pages 983-986

  Viola, Shelton ^a   Traer, Elie ^a   Huan, Jianya ^a   Hornick, Noah I ^a   Tyner, Jeffrey W ^a   Agarwal, Anupriya ^a   Loriaux, Marc ^a,b   Johnstone, Brian ^b   Kurre, Peter ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Acute myeloid leukaemia; Chemo resistance; Exosomes; MicroRNA; Stroma

Indexed keywords

CD45 ANTIGEN; CYTARABINE; FLT3 INHIBITOR; MICRORNA; PROTEIN TYROSINE KINASE INHIBITOR; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; RNA; THY 1 ANTIGEN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE;

ACUTE MYELOBLASTIC LEUKEMIA; APOPTOSIS; BONE MARROW STROMA CELL; CANCER RECURRENCE; CANCER RESISTANCE; CELL DIFFERENTIATION; CELL PROTECTION; CXCL1 GENE; CXCL12 GENE; CYTOKINE RELEASE; DOWN REGULATION; ELECTRON MICROSCOPY; EXOSOME; GENE; GENE EXPRESSION; HIGH RISK PATIENT; HUMAN; KITLG GENE; LETTER; LEUKEMIA CELL; LEUKEMOGENESIS; MIR155 GENE; MIR375 GENE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL NICHE; ULTRACENTRIFUGATION; WESTERN BLOTTING; ACUTE MYELOID LEUKEMIA; ADOLESCENT; ADULT; AGED; ANTAGONISTS AND INHIBITORS; CHILD; DRUG RESISTANCE; FEMALE; MALE; MESENCHYMAL STROMA CELL; MIDDLE AGED; PATHOLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANTINEOPLASTIC AGENTS; CHILD; DRUG RESISTANCE, NEOPLASM; EXOSOMES; FEMALE; HUMANS; LEUKEMIA, MYELOID, ACUTE; MALE; MESENCHYMAL STROMAL CELLS; MIDDLE AGED; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; YOUNG ADULT;

EID: 84960106140     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.13551     Document Type: Letter

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