AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB

Science Signaling

Volumn 9, Issue 444, 2016, Pages

  Hornick, Noah I ^a,b   Doron, Ben ^a,b   Abdelhamed, Sherif ^a,b   Huan, Jianya ^a,b   Harrington, Christina A ^b   Shen, Rongkun ^b,c   Cambronne, Xiaolu A ^b   Verghese, Santhosh Chakkaramakkil ^a,b   Kurre, Peter ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; CHECKPOINT KINASE 2; DNA METHYLTRANSFERASE 1; MICRORNA; MICRORNA 132; MICRORNA 137; MICRORNA 150; MICRORNA 155; MIXED LINEAGE LEUKEMIA PROTEIN; PROTEIN C MYB; PROTEIN P53; RNA INDUCED SILENCING COMPLEX; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG; MIRN150 MICRORNA, HUMAN; MIRN155 MICRORNA, HUMAN; RNA;

ACUTE MYELOBLASTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CLONOGENESIS; COLONY FORMING UNIT; CONTROLLED STUDY; EXOSOME; GENE TARGETING; HEMATOPOIESIS; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; ONCOGENE C KIT; ONCOGENE C MYB; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; RNA TRANSLATION; STEM CELL NICHE; TUMOR MICROENVIRONMENT; UNTRANSLATED REGION; ACUTE MYELOID LEUKEMIA; ANIMAL; BIOSYNTHESIS; CANCER TRANSPLANTATION; GENETICS; HL-60 CELL LINE; HUMAN; METABOLISM; PATHOLOGY; XENOGRAFT;

ANIMALS; EXOSOMES; HEMATOPOIESIS; HETEROGRAFTS; HL-60 CELLS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MICE; MICRORNAS; NEOPLASM TRANSPLANTATION; PROTO-ONCOGENE PROTEINS C-MYB; RNA, NEOPLASM;

EID: 84988845025     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aaf2797     Document Type: Article

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