TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis

Nature

Volumn 554, Issue 7693, 2018, Pages 538-543

  Tauriello, Daniele V F ^a,b   Palomo Ponce, Sergio ^a,b   Stork, Diana ^a   Berenguer Llergo, Antonio ^a   Badia Ramentol, Jordi ^a   Iglesias, Mar ^b,c,d   Sevillano, Marta ^a,b   Ibiza, Sales ^a   Cañellas, Adrià ^a   Hernando Momblona, Xavier ^a,b   Byrom, Daniel ^a   Matarin, Joan A ^a   Calon, Alexandre ^a,f   Rivas, Elisa I ^a,f   Nebreda, Angel R ^a,e   Riera, Antoni ^a,f   Attolini, Camille Stephan Otto ^a   Batlle, Eduard ^a,b,e  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^b Centro de Investigación Biomédica en Red de Cáncer   (Spain)

^c HOSPITAL DEL MAR   (Spain)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^e INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^f UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BUPRENORPHINE; GALUNISERTIB; PROGRAMMED DEATH 1 LIGAND 1; TAMOXIFEN; TRANSFORMING GROWTH FACTOR BETA; TRYPSIN; PROGRAMMED DEATH 1 RECEPTOR;

ADULT; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GENETICS; CANCER INHIBITION; CELL CYCLE CHECKPOINT; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; HUMAN; HUMAN CELL; IMMUNE EVASION; IMMUNOTHERAPY; INTESTINAL STEM CELL; INTESTINE TUMOR; LIVER METASTASIS; METASTATIC COLON CANCER; MICROSATELLITE MARKER; MOUSE; MUTATION; NONHUMAN; ORGANOID; PRIORITY JOURNAL; STROMA CELL; TGF BETA SIGNALING; TUMOR MICROENVIRONMENT; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL DIFFERENTIATION; COLON TUMOR; CYTOLOGY; DISEASE MODEL; DRUG EFFECT; DRUG POTENTIATION; FEMALE; GENETICS; IMMUNOLOGY; INTESTINE; LIVER TUMOR; MALE; METABOLISM; METASTASIS; PATHOLOGY; SECONDARY; STEM CELL; TH1 CELL;

MUS;

ALLELES; ANIMALS; CELL DIFFERENTIATION; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; FEMALE; HUMANS; IMMUNE EVASION; IMMUNOTHERAPY; INTESTINES; LIVER NEOPLASMS; MALE; MICE; MUTATION; NEOPLASM METASTASIS; PROGRAMMED CELL DEATH 1 RECEPTOR; STEM CELLS; T-LYMPHOCYTES, CYTOTOXIC; TH1 CELLS; TRANSFORMING GROWTH FACTOR BETA; TUMOR MICROENVIRONMENT;

EID: 85042540245     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature25492     Document Type: Article

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