-
1
-
-
84929051903
-
Toxic oligomer species of amyloid-beta in Alzheimer's disease, a timing issue
-
Lesne, S.E., Toxic oligomer species of amyloid-beta in Alzheimer's disease, a timing issue. Swiss Med Wkly, 144, 2014, w14021.
-
(2014)
Swiss Med Wkly
, vol.144
, pp. w14021
-
-
Lesne, S.E.1
-
2
-
-
84857642949
-
The toxic Abeta oligomer and Alzheimer's disease: an emperor in need of clothes
-
Benilova, I., Karran, E., De Strooper, B., The toxic Abeta oligomer and Alzheimer's disease: an emperor in need of clothes. Nat Neurosci 15 (2012), 349–357.
-
(2012)
Nat Neurosci
, vol.15
, pp. 349-357
-
-
Benilova, I.1
Karran, E.2
De Strooper, B.3
-
3
-
-
84860215480
-
Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature
-
Nelson, P.T., Alafuzoff, I., Bigio, E.H., Bouras, C., Braak, H., Cairns, N.J., et al. Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. J Neuropathol Exp Neurol 71 (2012), 362–381.
-
(2012)
J Neuropathol Exp Neurol
, vol.71
, pp. 362-381
-
-
Nelson, P.T.1
Alafuzoff, I.2
Bigio, E.H.3
Bouras, C.4
Braak, H.5
Cairns, N.J.6
-
4
-
-
0014313861
-
The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects
-
Blessed, G., Tomlinson, B.E., Roth, M., The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry 114 (1968), 797–811.
-
(1968)
Br J Psychiatry
, vol.114
, pp. 797-811
-
-
Blessed, G.1
Tomlinson, B.E.2
Roth, M.3
-
5
-
-
0025987048
-
Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment
-
Terry, R.D., Masliah, E., Salmon, D.P., Butters, N., DeTeresa, R., Hill, R., Hansen, L.A., Katzman, R., Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 30 (1991), 572–580.
-
(1991)
Ann Neurol
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
Masliah, E.2
Salmon, D.P.3
Butters, N.4
DeTeresa, R.5
Hill, R.6
Hansen, L.A.7
Katzman, R.8
-
6
-
-
0026740795
-
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
-
Arriagada, P.V., Growdon, J.H., Hedley-Whyte, E.T., Hyman, B.T., Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 42 (1992), 631–639.
-
(1992)
Neurology
, vol.42
, pp. 631-639
-
-
Arriagada, P.V.1
Growdon, J.H.2
Hedley-Whyte, E.T.3
Hyman, B.T.4
-
7
-
-
0027468235
-
Neuropathological indexes of Alzheimer's disease in demented and nondemented persons aged 80 years and older
-
Berg, L., McKeel, D.W. Jr., Miller, J.P., Baty, J., Morris, J.C., Neuropathological indexes of Alzheimer's disease in demented and nondemented persons aged 80 years and older. Arch Neurol 50 (1993), 349–358.
-
(1993)
Arch Neurol
, vol.50
, pp. 349-358
-
-
Berg, L.1
McKeel, D.W.2
Miller, J.P.3
Baty, J.4
Morris, J.C.5
-
8
-
-
0025773225
-
Neuritic pathology and dementia in Alzheimer's disease
-
McKee, A.C., Kosik, K.S., Kowall, N.W., Neuritic pathology and dementia in Alzheimer's disease. Ann Neurol 30 (1991), 156–165.
-
(1991)
Ann Neurol
, vol.30
, pp. 156-165
-
-
McKee, A.C.1
Kosik, K.S.2
Kowall, N.W.3
-
9
-
-
84872379077
-
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
-
Jack, C.R. Jr., Knopman, D.S., Jagust, W.J., Petersen, R.C., Weiner, M.W., Aisen, P.S., Shaw, L.M., Vemuri, P., Wiste, H.J., Weigand, S.D., Lesnick, T.G., Pankratz, V.S., Donohue, M.C., Trojanowski, J.Q., Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol 12 (2013), 207–216.
-
(2013)
Lancet Neurol
, vol.12
, pp. 207-216
-
-
Jack, C.R.1
Knopman, D.S.2
Jagust, W.J.3
Petersen, R.C.4
Weiner, M.W.5
Aisen, P.S.6
Shaw, L.M.7
Vemuri, P.8
Wiste, H.J.9
Weigand, S.D.10
Lesnick, T.G.11
Pankratz, V.S.12
Donohue, M.C.13
Trojanowski, J.Q.14
-
10
-
-
72049130805
-
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
-
Jack, C.R. Jr., Knopman, D.S., Jagust, W.J., Shaw, L.M., Aisen, P.S., Weiner, M.W., Petersen, R.C., Trojanowski, J.Q., Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol 9 (2010), 119–128.
-
(2010)
Lancet Neurol
, vol.9
, pp. 119-128
-
-
Jack, C.R.1
Knopman, D.S.2
Jagust, W.J.3
Shaw, L.M.4
Aisen, P.S.5
Weiner, M.W.6
Petersen, R.C.7
Trojanowski, J.Q.8
-
11
-
-
77953675879
-
Probing the biology of Alzheimer's disease in mice
-
Ashe, K.H., Zahs, K.R., Probing the biology of Alzheimer's disease in mice. Neuron 66 (2010), 631–645.
-
(2010)
Neuron
, vol.66
, pp. 631-645
-
-
Ashe, K.H.1
Zahs, K.R.2
-
12
-
-
84875449522
-
Cognition and amyloid load in Alzheimer disease imaged with florbetapir F 18(AV-45) positron emission tomography
-
Rosenberg, P.B., Wong, D.F., Edell, S.L., Ross, J.S., Joshi, A.D., Brasic, J.R., Zhou, Y., Raymont, V., Kumar, A., Ravert, H.T., Dannals, R.F., Pontecorvo, M.J., Skovronsky, D.M., Lyketsos, C.G., Cognition and amyloid load in Alzheimer disease imaged with florbetapir F 18(AV-45) positron emission tomography. Am J Geriatr Psychiatry 21 (2013), 272–278.
-
(2013)
Am J Geriatr Psychiatry
, vol.21
, pp. 272-278
-
-
Rosenberg, P.B.1
Wong, D.F.2
Edell, S.L.3
Ross, J.S.4
Joshi, A.D.5
Brasic, J.R.6
Zhou, Y.7
Raymont, V.8
Kumar, A.9
Ravert, H.T.10
Dannals, R.F.11
Pontecorvo, M.J.12
Skovronsky, D.M.13
Lyketsos, C.G.14
-
13
-
-
84875367717
-
Amyloid imaging and cognitive decline in nondemented oldest-old: the 90+ Study
-
Kawas, C.H., Greenia, D.E., Bullain, S.S., Clark, C.M., Pontecorvo, M.J., Joshi, A.D., Corrada, M.M., Amyloid imaging and cognitive decline in nondemented oldest-old: the 90+ Study. Alzheimers Dement 9 (2013), 199–203.
-
(2013)
Alzheimers Dement
, vol.9
, pp. 199-203
-
-
Kawas, C.H.1
Greenia, D.E.2
Bullain, S.S.3
Clark, C.M.4
Pontecorvo, M.J.5
Joshi, A.D.6
Corrada, M.M.7
-
14
-
-
84861606292
-
Effects of beta-amyloid accumulation on neural function during encoding across the adult lifespan
-
Kennedy, K.M., Rodrigue, K.M., Devous, M.D. Sr., Hebrank, A.C., Bischof, G.N., Park, D.C., Effects of beta-amyloid accumulation on neural function during encoding across the adult lifespan. Neuroimage 62 (2012), 1–8.
-
(2012)
Neuroimage
, vol.62
, pp. 1-8
-
-
Kennedy, K.M.1
Rodrigue, K.M.2
Devous, M.D.3
Hebrank, A.C.4
Bischof, G.N.5
Park, D.C.6
-
15
-
-
84858121162
-
beta-Amyloid burden in healthy aging: regional distribution and cognitive consequences
-
Rodrigue, K.M., Kennedy, K.M., Devous, M.D. Sr., Rieck, J.R., Hebrank, A.C., Diaz-Arrastia, R., Mathews, D., Park, D.C., beta-Amyloid burden in healthy aging: regional distribution and cognitive consequences. Neurology 78 (2012), 387–395.
-
(2012)
Neurology
, vol.78
, pp. 387-395
-
-
Rodrigue, K.M.1
Kennedy, K.M.2
Devous, M.D.3
Rieck, J.R.4
Hebrank, A.C.5
Diaz-Arrastia, R.6
Mathews, D.7
Park, D.C.8
-
16
-
-
84895802685
-
Relation of neuropathology with cognitive decline among older persons without dementia
-
Boyle, P.A., Yu, L., Wilson, R.S., Schneider, J.A., Bennett, D.A., Relation of neuropathology with cognitive decline among older persons without dementia. Front Aging Neurosci, 5, 2013, 50.
-
(2013)
Front Aging Neurosci
, vol.5
, pp. 50
-
-
Boyle, P.A.1
Yu, L.2
Wilson, R.S.3
Schneider, J.A.4
Bennett, D.A.5
-
17
-
-
84871200927
-
Stronger effect of amyloid load than APOE genotype on cognitive decline in healthy older adults
-
Lim, Y.Y., Ellis, K.A., Pietrzak, R.H., Ames, D., Darby, D., Harrington, K., Martins, R.N., Masters, C.L., Rowe, C., Savage, G., Szoeke, C., Villemagne, V.L., Maruff, P., Stronger effect of amyloid load than APOE genotype on cognitive decline in healthy older adults. Neurology 79 (2012), 1645–1652.
-
(2012)
Neurology
, vol.79
, pp. 1645-1652
-
-
Lim, Y.Y.1
Ellis, K.A.2
Pietrzak, R.H.3
Ames, D.4
Darby, D.5
Harrington, K.6
Martins, R.N.7
Masters, C.L.8
Rowe, C.9
Savage, G.10
Szoeke, C.11
Villemagne, V.L.12
Maruff, P.13
-
18
-
-
79957800704
-
Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden
-
Drzezga, A., Becker, J.A., Van Dijk, K.R., Sreenivasan, A., Talukdar, T., Sullivan, C., Schultz, A.P., Sepulcre, J., Putcha, D., Greve, D., Johnson, K.A., Sperling, R.A., Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden. Brain 134 (2011), 1635–1646.
-
(2011)
Brain
, vol.134
, pp. 1635-1646
-
-
Drzezga, A.1
Becker, J.A.2
Van Dijk, K.R.3
Sreenivasan, A.4
Talukdar, T.5
Sullivan, C.6
Schultz, A.P.7
Sepulcre, J.8
Putcha, D.9
Greve, D.10
Johnson, K.A.11
Sperling, R.A.12
-
19
-
-
79952162530
-
Independent contribution of temporal beta-amyloid deposition to memory decline in the pre-dementia phase of Alzheimer's disease
-
Chetelat, G., Villemagne, V.L., Pike, K.E., Ellis, K.A., Bourgeat, P., Jones, G., O'Keefe, G.J., Salvado, O., Szoeke, C., Martins, R.N., Ames, D., Masters, C.L., Rowe, C.C., Independent contribution of temporal beta-amyloid deposition to memory decline in the pre-dementia phase of Alzheimer's disease. Brain 134 (2011), 798–807.
-
(2011)
Brain
, vol.134
, pp. 798-807
-
-
Chetelat, G.1
Villemagne, V.L.2
Pike, K.E.3
Ellis, K.A.4
Bourgeat, P.5
Jones, G.6
O'Keefe, G.J.7
Salvado, O.8
Szoeke, C.9
Martins, R.N.10
Ames, D.11
Masters, C.L.12
Rowe, C.C.13
-
20
-
-
29644440011
-
Persistent amyloidosis following suppression of Aβ production in a transgenic model of Alzheimer's disease
-
Jankowsky, J.L., Slunt, H.H., Gonzales, V., Savonenko, A.V., Wen, J.C., Jenkins, N.A., Copeland, N.G., Younkin, L.H., Lester, H.A., Younkin, S.G., Borchelt, D.R., Persistent amyloidosis following suppression of Aβ production in a transgenic model of Alzheimer's disease. PLoS Med, 2, 2005, e355.
-
(2005)
PLoS Med
, vol.2
, pp. e355
-
-
Jankowsky, J.L.1
Slunt, H.H.2
Gonzales, V.3
Savonenko, A.V.4
Wen, J.C.5
Jenkins, N.A.6
Copeland, N.G.7
Younkin, L.H.8
Lester, H.A.9
Younkin, S.G.10
Borchelt, D.R.11
-
21
-
-
0029807527
-
Control of memory formation through regulated expression of a CaMKII transgene
-
Mayford, M., Bach, M.E., Huang, Y.Y., Wang, L., Hawkins, R.D., Kandel, E.R., Control of memory formation through regulated expression of a CaMKII transgene. Science 274 (1996), 1678–1683.
-
(1996)
Science
, vol.274
, pp. 1678-1683
-
-
Mayford, M.1
Bach, M.E.2
Huang, Y.Y.3
Wang, L.4
Hawkins, R.D.5
Kandel, E.R.6
-
22
-
-
84864479496
-
Strain background influences neurotoxicity and behavioral abnormalities in mice expressing the tetracycline transactivator
-
Han, H.J., Allen, C.C., Buchovecky, C.M., Yetman, M.J., Born, H.A., Marin, M.A., Rodgers, S.P., Song, B.J., Lu, H.C., Justice, M.J., Probst, F.J., Jankowsky, J.L., Strain background influences neurotoxicity and behavioral abnormalities in mice expressing the tetracycline transactivator. J Neurosci 32 (2012), 10574–10586.
-
(2012)
J Neurosci
, vol.32
, pp. 10574-10586
-
-
Han, H.J.1
Allen, C.C.2
Buchovecky, C.M.3
Yetman, M.J.4
Born, H.A.5
Marin, M.A.6
Rodgers, S.P.7
Song, B.J.8
Lu, H.C.9
Justice, M.J.10
Probst, F.J.11
Jankowsky, J.L.12
-
23
-
-
84862264187
-
Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult
-
Rodgers, S.P., Born, H.A., Das, P., Jankowsky, J.L., Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult. Mol Neurodegener, 7, 2012, 28.
-
(2012)
Mol Neurodegener
, vol.7
, pp. 28
-
-
Rodgers, S.P.1
Born, H.A.2
Das, P.3
Jankowsky, J.L.4
-
24
-
-
84901779689
-
Genetic modulation of soluble abeta rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease
-
Fowler, S.W., Chiang, A.C., Savjani, R.R., Larson, M.E., Sherman, M.A., Schuler, D.R., Cirrito, J.R., Lesne, S.E., Jankowsky, J.L., Genetic modulation of soluble abeta rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease. J Neurosci 34 (2014), 7871–7885.
-
(2014)
J Neurosci
, vol.34
, pp. 7871-7885
-
-
Fowler, S.W.1
Chiang, A.C.2
Savjani, R.R.3
Larson, M.E.4
Sherman, M.A.5
Schuler, D.R.6
Cirrito, J.R.7
Lesne, S.E.8
Jankowsky, J.L.9
-
25
-
-
30444454374
-
Morris water maze search strategy analysis in PDAPP mice before and after experimental traumatic brain injury
-
Brody, D.L., Holtzman, D.M., Morris water maze search strategy analysis in PDAPP mice before and after experimental traumatic brain injury. Exp Neurol 197 (2006), 330–340.
-
(2006)
Exp Neurol
, vol.197
, pp. 330-340
-
-
Brody, D.L.1
Holtzman, D.M.2
-
26
-
-
0025908356
-
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD), part II: standardization of the neuropathologic assessment of Alzheimer's disease
-
Mirra, S.S., Heyman, A., McKeel, D., Sumi, S.M., Crain, B.J., Brownlee, L.M., Vogel, F.S., Hughes, J.P., van Belle, G., Berg, L., The Consortium to Establish a Registry for Alzheimer's Disease (CERAD), part II: standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 41 (1991), 479–486.
-
(1991)
Neurology
, vol.41
, pp. 479-486
-
-
Mirra, S.S.1
Heyman, A.2
McKeel, D.3
Sumi, S.M.4
Crain, B.J.5
Brownlee, L.M.6
Vogel, F.S.7
Hughes, J.P.8
van Belle, G.9
Berg, L.10
-
27
-
-
84934444742
-
Detecting abeta*56 oligomers in brain tissues
-
Sherman, M.A., Lesne, S.E., Detecting abeta*56 oligomers in brain tissues. Methods Mol Biol 670 (2011), 45–56.
-
(2011)
Methods Mol Biol
, vol.670
, pp. 45-56
-
-
Sherman, M.A.1
Lesne, S.E.2
-
28
-
-
33645038471
-
A specific amyloid-beta protein assembly in the brain impairs memory
-
Lesne, S., Koh, M.T., Kotilinek, L., Kayed, R., Glabe, C.G., Yang, A., Gallagher, M., Ashe, K.H., A specific amyloid-beta protein assembly in the brain impairs memory. Nature 440 (2006), 352–357.
-
(2006)
Nature
, vol.440
, pp. 352-357
-
-
Lesne, S.1
Koh, M.T.2
Kotilinek, L.3
Kayed, R.4
Glabe, C.G.5
Yang, A.6
Gallagher, M.7
Ashe, K.H.8
-
29
-
-
0037088956
-
Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months
-
King, D.L., Arendash, G.W., Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months. Physiol Behav 75 (2002), 627–642.
-
(2002)
Physiol Behav
, vol.75
, pp. 627-642
-
-
King, D.L.1
Arendash, G.W.2
-
30
-
-
33845891619
-
Spatial learning and psychomotor performance of C57BL/6 mice: age sensitivity and reliability of individual differences
-
de Fiebre, N.C., Sumien, N., Forster, M.J., de Fiebre, C.M., Spatial learning and psychomotor performance of C57BL/6 mice: age sensitivity and reliability of individual differences. Age (Dordr) 28 (2006), 235–253.
-
(2006)
Age (Dordr)
, vol.28
, pp. 235-253
-
-
de Fiebre, N.C.1
Sumien, N.2
Forster, M.J.3
de Fiebre, C.M.4
-
31
-
-
35148819275
-
Age-dependent effects of environmental enrichment on spatial reference memory in male mice
-
Harburger, L.L., Lambert, T.J., Frick, K.M., Age-dependent effects of environmental enrichment on spatial reference memory in male mice. Behav Brain Res 185 (2007), 43–48.
-
(2007)
Behav Brain Res
, vol.185
, pp. 43-48
-
-
Harburger, L.L.1
Lambert, T.J.2
Frick, K.M.3
-
32
-
-
68049116930
-
The effects of aging on N-methyl-D-aspartate receptor subunits in the synaptic membrane and relationships to long-term spatial memory
-
Zhao, X., Rosenke, R., Kronemann, D., Brim, B., Das, S.R., Dunah, A.W., Magnusson, K.R., The effects of aging on N-methyl-D-aspartate receptor subunits in the synaptic membrane and relationships to long-term spatial memory. Neuroscience 162 (2009), 933–945.
-
(2009)
Neuroscience
, vol.162
, pp. 933-945
-
-
Zhao, X.1
Rosenke, R.2
Kronemann, D.3
Brim, B.4
Das, S.R.5
Dunah, A.W.6
Magnusson, K.R.7
-
33
-
-
84877293577
-
Brain amyloid-beta oligomers in ageing and Alzheimer's disease
-
Lesne, S.E., Sherman, M.A., Grant, M., Kuskowski, M., Schneider, J.A., Bennett, D.A., Ashe, K.H., Brain amyloid-beta oligomers in ageing and Alzheimer's disease. Brain 136 (2013), 1383–1398.
-
(2013)
Brain
, vol.136
, pp. 1383-1398
-
-
Lesne, S.E.1
Sherman, M.A.2
Grant, M.3
Kuskowski, M.4
Schneider, J.A.5
Bennett, D.A.6
Ashe, K.H.7
-
34
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed, R., Head, E., Thompson, J.L., McIntire, T.M., Milton, S.C., Cotman, C.W., Glabe, C.G., Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300 (2003), 486–489.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
35
-
-
84944324335
-
eta-Secretase processing of APP inhibits neuronal activity in the hippocampus
-
Willem, M., Tahirovic, S., Busche, M.A., Ovsepian, S.V., Chafai, M., Kootar, S., Hornburg, D., Evans, L.D., Moore, S., Daria, A., Hampel, H., Muller, V., Giudici, C., Nuscher, B., Wenninger-Weinzierl, A., Kremmer, E., Heneka, M.T., Thal, D.R., Giedraitis, V., Lannfelt, L., Muller, U., Livesey, F.J., Meissner, F., Herms, J., Konnerth, A., Marie, H., Haass, C., eta-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature 526 (2015), 443–447.
-
(2015)
Nature
, vol.526
, pp. 443-447
-
-
Willem, M.1
Tahirovic, S.2
Busche, M.A.3
Ovsepian, S.V.4
Chafai, M.5
Kootar, S.6
Hornburg, D.7
Evans, L.D.8
Moore, S.9
Daria, A.10
Hampel, H.11
Muller, V.12
Giudici, C.13
Nuscher, B.14
Wenninger-Weinzierl, A.15
Kremmer, E.16
Heneka, M.T.17
Thal, D.R.18
Giedraitis, V.19
Lannfelt, L.20
Muller, U.21
Livesey, F.J.22
Meissner, F.23
Herms, J.24
Konnerth, A.25
Marie, H.26
Haass, C.27
more..
-
36
-
-
84948799632
-
N-terminal extensions retard Abeta42 fibril formation but allow cross-seeding and coaggregation with Abeta42
-
Szczepankiewicz, O., Linse, B., Meisl, G., Thulin, E., Frohm, B., Sala Frigerio, C., Colvin, M.T., Jacavone, A.C., Griffin, R.G., Knowles, T., Walsh, D.M., Linse, S., N-terminal extensions retard Abeta42 fibril formation but allow cross-seeding and coaggregation with Abeta42. J Am Chem Soc 137 (2015), 14673–14685.
-
(2015)
J Am Chem Soc
, vol.137
, pp. 14673-14685
-
-
Szczepankiewicz, O.1
Linse, B.2
Meisl, G.3
Thulin, E.4
Frohm, B.5
Sala Frigerio, C.6
Colvin, M.T.7
Jacavone, A.C.8
Griffin, R.G.9
Knowles, T.10
Walsh, D.M.11
Linse, S.12
-
37
-
-
33749020837
-
Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host
-
Meyer-Luehmann, M., Coomaraswamy, J., Bolmont, T., Kaeser, S., Schaefer, C., Kilger, E., Neuenschwander, A., Abramowski, D., Frey, P., Jaton, A.L., Vigouret, J.M., Paganetti, P., Walsh, D.M., Mathews, P.M., Ghiso, J., Staufenbiel, M., Walker, L.C., Jucker, M., Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host. Science 313 (2006), 1781–1784.
-
(2006)
Science
, vol.313
, pp. 1781-1784
-
-
Meyer-Luehmann, M.1
Coomaraswamy, J.2
Bolmont, T.3
Kaeser, S.4
Schaefer, C.5
Kilger, E.6
Neuenschwander, A.7
Abramowski, D.8
Frey, P.9
Jaton, A.L.10
Vigouret, J.M.11
Paganetti, P.12
Walsh, D.M.13
Mathews, P.M.14
Ghiso, J.15
Staufenbiel, M.16
Walker, L.C.17
Jucker, M.18
-
38
-
-
84869992747
-
The complex PrP(c)-Fyn couples human oligomeric Abeta with pathological tau changes in Alzheimer's disease
-
Larson, M., Sherman, M.A., Amar, F., Nuvolone, M., Schneider, J.A., Bennett, D.A., Aguzzi, A., Lesne, S.E., The complex PrP(c)-Fyn couples human oligomeric Abeta with pathological tau changes in Alzheimer's disease. J Neurosci 32 (2012), 16857–16871a.
-
(2012)
J Neurosci
, vol.32
, pp. 16857-16871a
-
-
Larson, M.1
Sherman, M.A.2
Amar, F.3
Nuvolone, M.4
Schneider, J.A.5
Bennett, D.A.6
Aguzzi, A.7
Lesne, S.E.8
-
39
-
-
84966708925
-
Amyloid-beta receptors: the good, the bad, and the prion protein
-
Jarosz-Griffiths, H.H., Noble, E., Rushworth, J.V., Hooper, N.M., Amyloid-beta receptors: the good, the bad, and the prion protein. J Biol Chem 291 (2016), 3174–3183.
-
(2016)
J Biol Chem
, vol.291
, pp. 3174-3183
-
-
Jarosz-Griffiths, H.H.1
Noble, E.2
Rushworth, J.V.3
Hooper, N.M.4
-
40
-
-
79951761390
-
The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?
-
Broersen, K., Rousseau, F., Schymkowitz, J., The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?. Alzheimers Res Ther, 2, 2010, 12.
-
(2010)
Alzheimers Res Ther
, vol.2
, pp. 12
-
-
Broersen, K.1
Rousseau, F.2
Schymkowitz, J.3
-
41
-
-
84937640921
-
Quaternary structure defines a large class of amyloid-beta oligomers neutralized by sequestration
-
Liu, P., Reed, M.N., Kotilinek, L.A., Grant, M.K., Forster, C.L., Qiang, W., Shapiro, S.L., Reichl, J.H., Chiang, A.C., Jankowsky, J.L., Wilmot, C.M., Cleary, J.P., Zahs, K.R., Ashe, K.H., Quaternary structure defines a large class of amyloid-beta oligomers neutralized by sequestration. Cell Rep 11 (2015), 1760–1771.
-
(2015)
Cell Rep
, vol.11
, pp. 1760-1771
-
-
Liu, P.1
Reed, M.N.2
Kotilinek, L.A.3
Grant, M.K.4
Forster, C.L.5
Qiang, W.6
Shapiro, S.L.7
Reichl, J.H.8
Chiang, A.C.9
Jankowsky, J.L.10
Wilmot, C.M.11
Cleary, J.P.12
Zahs, K.R.13
Ashe, K.H.14
-
42
-
-
68149162581
-
Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction
-
Tomic, J.L., Pensalfini, A., Head, E., Glabe, C.G., Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction. Neurobiol Dis 35 (2009), 352–358.
-
(2009)
Neurobiol Dis
, vol.35
, pp. 352-358
-
-
Tomic, J.L.1
Pensalfini, A.2
Head, E.3
Glabe, C.G.4
-
43
-
-
84864497129
-
Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice
-
Rasool, S., Albay, R. 3rd, Martinez-Coria, H., Breydo, L., Wu, J., Milton, S., Misra, S., Tran, A., Pensalfini, A., Laferla, F., Kayed, R., Glabe, C.G., Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice. Mol Neurodegener, 7, 2012, 37.
-
(2012)
Mol Neurodegener
, vol.7
, pp. 37
-
-
Rasool, S.1
Albay, R.2
Martinez-Coria, H.3
Breydo, L.4
Wu, J.5
Milton, S.6
Misra, S.7
Tran, A.8
Pensalfini, A.9
Laferla, F.10
Kayed, R.11
Glabe, C.G.12
-
44
-
-
84885961431
-
Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Abeta deposition and tau pathology in 3xTg-AD mice
-
Rasool, S., Martinez-Coria, H., Wu, J.W., LaFerla, F., Glabe, C.G., Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Abeta deposition and tau pathology in 3xTg-AD mice. J Neurochem 126 (2013), 473–482.
-
(2013)
J Neurochem
, vol.126
, pp. 473-482
-
-
Rasool, S.1
Martinez-Coria, H.2
Wu, J.W.3
LaFerla, F.4
Glabe, C.G.5
-
45
-
-
84994337754
-
Effective anti-Alzheimer Abeta therapy involves depletion of specific Abeta oligomer subtypes
-
Knight, E.M., Kim, S.H., Kottwitz, J.C., Hatami, A., Albay, R., Suzuki, A., Lublin, A., Alberini, C.M., Klein, W.L., Szabo, P., Relkin, N.R., Ehrlich, M., Glabe, C.G., Gandy, S., Steele, J.W., Effective anti-Alzheimer Abeta therapy involves depletion of specific Abeta oligomer subtypes. Neurol Neuroimmunol Neuroinflamm, 3, 2016, e237.
-
(2016)
Neurol Neuroimmunol Neuroinflamm
, vol.3
, pp. e237
-
-
Knight, E.M.1
Kim, S.H.2
Kottwitz, J.C.3
Hatami, A.4
Albay, R.5
Suzuki, A.6
Lublin, A.7
Alberini, C.M.8
Klein, W.L.9
Szabo, P.10
Relkin, N.R.11
Ehrlich, M.12
Glabe, C.G.13
Gandy, S.14
Steele, J.W.15
-
46
-
-
85019231994
-
The amyloid-beta oligomer Abeta*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation
-
Amar, F., Sherman, M.A., Rush, T., Larson, M., Boyle, G., Chang, L., Gotz, J., Buisson, A., Lesne, S.E., The amyloid-beta oligomer Abeta*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation. Sci Signal, 10, 2017, eaal2021.
-
(2017)
Sci Signal
, vol.10
, pp. eaal2021
-
-
Amar, F.1
Sherman, M.A.2
Rush, T.3
Larson, M.4
Boyle, G.5
Chang, L.6
Gotz, J.7
Buisson, A.8
Lesne, S.E.9
-
47
-
-
70349973683
-
Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life
-
Shankar, G.M., Leissring, M.A., Adame, A., Sun, X., Spooner, E., Masliah, E., Selkoe, D.J., Lemere, C.A., Walsh, D.M., Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life. Neurobiol Dis 36 (2009), 293–302.
-
(2009)
Neurobiol Dis
, vol.36
, pp. 293-302
-
-
Shankar, G.M.1
Leissring, M.A.2
Adame, A.3
Sun, X.4
Spooner, E.5
Masliah, E.6
Selkoe, D.J.7
Lemere, C.A.8
Walsh, D.M.9
-
48
-
-
33144487701
-
Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease: a link between Abeta and tau pathology
-
Oddo, S., Caccamo, A., Tran, L., Lambert, M.P., Glabe, C.G., Klein, W.L., LaFerla, F.M., Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease: a link between Abeta and tau pathology. J Biol Chem 281 (2006), 1599–1604.
-
(2006)
J Biol Chem
, vol.281
, pp. 1599-1604
-
-
Oddo, S.1
Caccamo, A.2
Tran, L.3
Lambert, M.P.4
Glabe, C.G.5
Klein, W.L.6
LaFerla, F.M.7
-
49
-
-
84901029497
-
Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models
-
Webster, S.J., Bachstetter, A.D., Nelson, P.T., Schmitt, F.A., Van Eldik, L.J., Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models. Front Genet, 5, 2014, 88.
-
(2014)
Front Genet
, vol.5
, pp. 88
-
-
Webster, S.J.1
Bachstetter, A.D.2
Nelson, P.T.3
Schmitt, F.A.4
Van Eldik, L.J.5
-
50
-
-
84903208566
-
Secreted amyloid beta-proteins in a cell culture model include N-terminally extended peptides that impair synaptic plasticity
-
Welzel, A.T., Maggio, J.E., Shankar, G.M., Walker, D.E., Ostaszewski, B.L., Li, S., Klyubin, I., Rowan, M.J., Seubert, P., Walsh, D.M., Selkoe, D.J., Secreted amyloid beta-proteins in a cell culture model include N-terminally extended peptides that impair synaptic plasticity. Biochemistry 53 (2014), 3908–3921.
-
(2014)
Biochemistry
, vol.53
, pp. 3908-3921
-
-
Welzel, A.T.1
Maggio, J.E.2
Shankar, G.M.3
Walker, D.E.4
Ostaszewski, B.L.5
Li, S.6
Klyubin, I.7
Rowan, M.J.8
Seubert, P.9
Walsh, D.M.10
Selkoe, D.J.11
-
51
-
-
42949155299
-
Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization
-
Klyubin, I., Betts, V., Welzel, A.T., Blennow, K., Zetterberg, H., Wallin, A., Lemere, C.A., Cullen, W.K., Peng, Y., Wisniewski, T., Selkoe, D.J., Anwyl, R., Walsh, D.M., Rowan, M.J., Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization. J Neurosci 28 (2008), 4231–4237.
-
(2008)
J Neurosci
, vol.28
, pp. 4231-4237
-
-
Klyubin, I.1
Betts, V.2
Welzel, A.T.3
Blennow, K.4
Zetterberg, H.5
Wallin, A.6
Lemere, C.A.7
Cullen, W.K.8
Peng, Y.9
Wisniewski, T.10
Selkoe, D.J.11
Anwyl, R.12
Walsh, D.M.13
Rowan, M.J.14
-
52
-
-
21044453723
-
Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo
-
Klyubin, I., Walsh, D.M., Lemere, C.A., Cullen, W.K., Shankar, G.M., Betts, V., Spooner, E.T., Jiang, L., Anwyl, R., Selkoe, D.J., Rowan, M.J., Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo. Nat Med 11 (2005), 556–561.
-
(2005)
Nat Med
, vol.11
, pp. 556-561
-
-
Klyubin, I.1
Walsh, D.M.2
Lemere, C.A.3
Cullen, W.K.4
Shankar, G.M.5
Betts, V.6
Spooner, E.T.7
Jiang, L.8
Anwyl, R.9
Selkoe, D.J.10
Rowan, M.J.11
-
53
-
-
49149124343
-
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
Shankar, G.M., Li, S., Mehta, T.H., Garcia-Munoz, A., Shepardson, N.E., Smith, I., Brett, F.M., Farrell, M.A., Rowan, M.J., Lemere, C.A., Regan, C.M., Walsh, D.M., Sabatini, B.L., Selkoe, D.J., Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med 14 (2008), 837–842.
-
(2008)
Nat Med
, vol.14
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
Brett, F.M.7
Farrell, M.A.8
Rowan, M.J.9
Lemere, C.A.10
Regan, C.M.11
Walsh, D.M.12
Sabatini, B.L.13
Selkoe, D.J.14
-
54
-
-
84873328025
-
Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls
-
Esparza, T.J., Zhao, H., Cirrito, J.R., Cairns, N.J., Bateman, R.J., Holtzman, D.M., Brody, D.L., Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls. Ann Neurol 73 (2013), 104–119.
-
(2013)
Ann Neurol
, vol.73
, pp. 104-119
-
-
Esparza, T.J.1
Zhao, H.2
Cirrito, J.R.3
Cairns, N.J.4
Bateman, R.J.5
Holtzman, D.M.6
Brody, D.L.7
-
55
-
-
84856353669
-
High-molecular weight Abeta oligomers and protofibrils are the predominant Abeta species in the native soluble protein fraction of the AD brain
-
Upadhaya, A.R., Lungrin, I., Yamaguchi, H., Fandrich, M., Thal, D.R., High-molecular weight Abeta oligomers and protofibrils are the predominant Abeta species in the native soluble protein fraction of the AD brain. J Cell Mol Med 16 (2012), 287–295.
-
(2012)
J Cell Mol Med
, vol.16
, pp. 287-295
-
-
Upadhaya, A.R.1
Lungrin, I.2
Yamaguchi, H.3
Fandrich, M.4
Thal, D.R.5
-
56
-
-
84865577637
-
Dispersible amyloid beta-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice
-
Rijal Upadhaya, A., Capetillo-Zarate, E., Kosterin, I., Abramowski, D., Kumar, S., Yamaguchi, H., Walter, J., Fandrich, M., Staufenbiel, M., Thal, D.R., Dispersible amyloid beta-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice. Neurobiol Aging 33 (2012), 2641–2660.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 2641-2660
-
-
Rijal Upadhaya, A.1
Capetillo-Zarate, E.2
Kosterin, I.3
Abramowski, D.4
Kumar, S.5
Yamaguchi, H.6
Walter, J.7
Fandrich, M.8
Staufenbiel, M.9
Thal, D.R.10
-
57
-
-
85015324796
-
Pre-plaque conformational changes in Alzheimer's disease-linked Abeta and APP
-
Klementieva, O., Willen, K., Martinsson, I., Israelsson, B., Engdahl, A., Cladera, J., Uvdal, P., Gouras, G.K., Pre-plaque conformational changes in Alzheimer's disease-linked Abeta and APP. Nat Commun, 8, 2017, 14726.
-
(2017)
Nat Commun
, vol.8
, pp. 14726
-
-
Klementieva, O.1
Willen, K.2
Martinsson, I.3
Israelsson, B.4
Engdahl, A.5
Cladera, J.6
Uvdal, P.7
Gouras, G.K.8
-
58
-
-
84995912064
-
Preparation of pure populations of covalently stabilized amyloid beta-protein oligomers of specific sizes
-
Hayden, E.Y., Conovaloff, J.L., Mason, A., Bitan, G., Teplow, D.B., Preparation of pure populations of covalently stabilized amyloid beta-protein oligomers of specific sizes. Anal Biochem 518 (2017), 78–85.
-
(2017)
Anal Biochem
, vol.518
, pp. 78-85
-
-
Hayden, E.Y.1
Conovaloff, J.L.2
Mason, A.3
Bitan, G.4
Teplow, D.B.5
-
59
-
-
80053616820
-
Molecular engineering of a secreted, highly homogeneous, and neurotoxic abeta dimer
-
Muller-Schiffmann, A., Andreyeva, A., Horn, A.H., Gottmann, K., Korth, C., Sticht, H., Molecular engineering of a secreted, highly homogeneous, and neurotoxic abeta dimer. ACS Chem Neurosci 2 (2011), 242–248.
-
(2011)
ACS Chem Neurosci
, vol.2
, pp. 242-248
-
-
Muller-Schiffmann, A.1
Andreyeva, A.2
Horn, A.H.3
Gottmann, K.4
Korth, C.5
Sticht, H.6
-
60
-
-
84896764452
-
Genetic suppression of transgenic APP rescues hypersynchronous network activity in a mouse model of Alzheimer's disease
-
Born, H.A., Kim, J.Y., Savjani, R.R., Das, P., Dabaghian, Y.A., Guo, Q., Yoo, J.W., Schuler, D.R., Cirrito, J.R., Zheng, H., Golde, T.E., Noebels, J.L., Jankowsky, J.L., Genetic suppression of transgenic APP rescues hypersynchronous network activity in a mouse model of Alzheimer's disease. J Neurosci 34 (2014), 3826–3840.
-
(2014)
J Neurosci
, vol.34
, pp. 3826-3840
-
-
Born, H.A.1
Kim, J.Y.2
Savjani, R.R.3
Das, P.4
Dabaghian, Y.A.5
Guo, Q.6
Yoo, J.W.7
Schuler, D.R.8
Cirrito, J.R.9
Zheng, H.10
Golde, T.E.11
Noebels, J.L.12
Jankowsky, J.L.13
-
61
-
-
79955128215
-
Biology and pathophysiology of the amyloid precursor protein
-
Zheng, H., Koo, E.H., Biology and pathophysiology of the amyloid precursor protein. Mol Neurodegener, 6, 2011, 27.
-
(2011)
Mol Neurodegener
, vol.6
, pp. 27
-
-
Zheng, H.1
Koo, E.H.2
-
62
-
-
84922942705
-
Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains
-
Bushman, D.M., Kaeser, G.E., Siddoway, B., Westra, J.W., Rivera, R.R., Rehen, S.K., Yung, Y.C., Chun, J., Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains. Elife, 4, 2015, e05116.
-
(2015)
Elife
, vol.4
, pp. e05116
-
-
Bushman, D.M.1
Kaeser, G.E.2
Siddoway, B.3
Westra, J.W.4
Rivera, R.R.5
Rehen, S.K.6
Yung, Y.C.7
Chun, J.8
-
63
-
-
84926370173
-
Neuroinflammation in Alzheimer's disease
-
Heneka, M.T., Carson, M.J., El Khoury, J., Landreth, G.E., Brosseron, F., Feinstein, D.L., et al. Neuroinflammation in Alzheimer's disease. Lancet Neurol 14 (2015), 388–405.
-
(2015)
Lancet Neurol
, vol.14
, pp. 388-405
-
-
Heneka, M.T.1
Carson, M.J.2
El Khoury, J.3
Landreth, G.E.4
Brosseron, F.5
Feinstein, D.L.6
-
64
-
-
84958225958
-
The cellular phase of Alzheimer's disease
-
De Strooper, B., Karran, E., The cellular phase of Alzheimer's disease. Cell 164 (2016), 603–615.
-
(2016)
Cell
, vol.164
, pp. 603-615
-
-
De Strooper, B.1
Karran, E.2
-
65
-
-
84941600256
-
Neuroinflammatory changes negatively impact on LTP: a focus on IL-1beta
-
Lynch, M.A., Neuroinflammatory changes negatively impact on LTP: a focus on IL-1beta. Brain Res 1621 (2015), 197–204.
-
(2015)
Brain Res
, vol.1621
, pp. 197-204
-
-
Lynch, M.A.1
-
66
-
-
84876847878
-
Chemokines and the hippocampus: a new perspective on hippocampal plasticity and vulnerability
-
Williamson, L.L., Bilbo, S.D., Chemokines and the hippocampus: a new perspective on hippocampal plasticity and vulnerability. Brain Behav Immun 30 (2013), 186–194.
-
(2013)
Brain Behav Immun
, vol.30
, pp. 186-194
-
-
Williamson, L.L.1
Bilbo, S.D.2
-
67
-
-
78651412528
-
Immune modulation of learning, memory, neural plasticity and neurogenesis
-
Yirmiya, R., Goshen, I., Immune modulation of learning, memory, neural plasticity and neurogenesis. Brain Behav Immun 25 (2011), 181–213.
-
(2011)
Brain Behav Immun
, vol.25
, pp. 181-213
-
-
Yirmiya, R.1
Goshen, I.2
-
68
-
-
84870932482
-
Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline
-
Vom Berg, J., Prokop, S., Miller, K.R., Obst, J., Kalin, R.E., Lopategui-Cabezas, I., Wegner, A., Mair, F., Schipke, C.G., Peters, O., Winter, Y., Becher, B., Heppner, F.L., Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline. Nat Med 18 (2012), 1812–1819.
-
(2012)
Nat Med
, vol.18
, pp. 1812-1819
-
-
Vom Berg, J.1
Prokop, S.2
Miller, K.R.3
Obst, J.4
Kalin, R.E.5
Lopategui-Cabezas, I.6
Wegner, A.7
Mair, F.8
Schipke, C.G.9
Peters, O.10
Winter, Y.11
Becher, B.12
Heppner, F.L.13
-
69
-
-
84920841382
-
NFkappaB-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease
-
Lian, H., Yang, L., Cole, A., Sun, L., Chiang, A.C., Fowler, S.W., Shim, D.J., Rodriguez-Rivera, J., Taglialatela, G., Jankowsky, J.L., Lu, H.C., Zheng, H., NFkappaB-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease. Neuron 85 (2015), 101–115.
-
(2015)
Neuron
, vol.85
, pp. 101-115
-
-
Lian, H.1
Yang, L.2
Cole, A.3
Sun, L.4
Chiang, A.C.5
Fowler, S.W.6
Shim, D.J.7
Rodriguez-Rivera, J.8
Taglialatela, G.9
Jankowsky, J.L.10
Lu, H.C.11
Zheng, H.12
-
70
-
-
84962418507
-
Complement and microglia mediate early synapse loss in Alzheimer mouse models
-
Hong, S., Beja-Glasser, V.F., Nfonoyim, B.M., Frouin, A., Li, S., Ramakrishnan, S., Merry, K.M., Shi, Q., Rosenthal, A., Barres, B.A., Lemere, C.A., Selkoe, D.J., Stevens, B., Complement and microglia mediate early synapse loss in Alzheimer mouse models. Science 352 (2016), 712–716.
-
(2016)
Science
, vol.352
, pp. 712-716
-
-
Hong, S.1
Beja-Glasser, V.F.2
Nfonoyim, B.M.3
Frouin, A.4
Li, S.5
Ramakrishnan, S.6
Merry, K.M.7
Shi, Q.8
Rosenthal, A.9
Barres, B.A.10
Lemere, C.A.11
Selkoe, D.J.12
Stevens, B.13
-
71
-
-
84936144528
-
The role of the tripartite glutamatergic synapse in the pathophysiology of Alzheimer's disease
-
Rudy, C.C., Hunsberger, H.C., Weitzner, D.S., Reed, M.N., The role of the tripartite glutamatergic synapse in the pathophysiology of Alzheimer's disease. Aging Dis 6 (2015), 131–148.
-
(2015)
Aging Dis
, vol.6
, pp. 131-148
-
-
Rudy, C.C.1
Hunsberger, H.C.2
Weitzner, D.S.3
Reed, M.N.4
-
72
-
-
70349431078
-
Axonopathy and cytoskeletal disruption in degenerative diseases of the central nervous system
-
Vickers, J.C., King, A.E., Woodhouse, A., Kirkcaldie, M.T., Staal, J.A., McCormack, G.H., Blizzard, C.A., Musgrove, R.E., Mitew, S., Liu, Y., Chuckowree, J.A., Bibari, O., Dickson, T.C., Axonopathy and cytoskeletal disruption in degenerative diseases of the central nervous system. Brain Res Bull 80 (2009), 217–223.
-
(2009)
Brain Res Bull
, vol.80
, pp. 217-223
-
-
Vickers, J.C.1
King, A.E.2
Woodhouse, A.3
Kirkcaldie, M.T.4
Staal, J.A.5
McCormack, G.H.6
Blizzard, C.A.7
Musgrove, R.E.8
Mitew, S.9
Liu, Y.10
Chuckowree, J.A.11
Bibari, O.12
Dickson, T.C.13
-
73
-
-
84867603343
-
Cognitive reserve in ageing and Alzheimer's disease
-
Stern, Y., Cognitive reserve in ageing and Alzheimer's disease. Lancet Neurol 11 (2012), 1006–1012.
-
(2012)
Lancet Neurol
, vol.11
, pp. 1006-1012
-
-
Stern, Y.1
-
74
-
-
77950538370
-
Cognition, reserve, and amyloid deposition in normal aging
-
Rentz, D.M., Locascio, J.J., Becker, J.A., Moran, E.K., Eng, E., Buckner, R.L., Sperling, R.A., Johnson, K.A., Cognition, reserve, and amyloid deposition in normal aging. Ann Neurol 67 (2010), 353–364.
-
(2010)
Ann Neurol
, vol.67
, pp. 353-364
-
-
Rentz, D.M.1
Locascio, J.J.2
Becker, J.A.3
Moran, E.K.4
Eng, E.5
Buckner, R.L.6
Sperling, R.A.7
Johnson, K.A.8
-
75
-
-
79957496944
-
Cognitive reserve and Alzheimer's disease biomarkers are independent determinants of cognition
-
Vemuri, P., Weigand, S.D., Przybelski, S.A., Knopman, D.S., Smith, G.E., Trojanowski, J.Q., Shaw, L.M., Decarli, C.S., Carmichael, O., Bernstein, M.A., Aisen, P.S., Weiner, M., Petersen, R.C., Jack, C.R. Jr., Alzheimer's Disease Neuroimaging Initiative. Cognitive reserve and Alzheimer's disease biomarkers are independent determinants of cognition. Brain 134 (2011), 1479–1492.
-
(2011)
Brain
, vol.134
, pp. 1479-1492
-
-
Vemuri, P.1
Weigand, S.D.2
Przybelski, S.A.3
Knopman, D.S.4
Smith, G.E.5
Trojanowski, J.Q.6
Shaw, L.M.7
Decarli, C.S.8
Carmichael, O.9
Bernstein, M.A.10
Aisen, P.S.11
Weiner, M.12
Petersen, R.C.13
Jack, C.R.14
-
76
-
-
55949096820
-
Alzheimer disease and cognitive reserve: variation of education effect with carbon 11-labeled Pittsburgh Compound B uptake
-
Roe, C.M., Mintun, M.A., D'Angelo, G., Xiong, C., Grant, E.A., Morris, J.C., Alzheimer disease and cognitive reserve: variation of education effect with carbon 11-labeled Pittsburgh Compound B uptake. Arch Neurol 65 (2008), 1467–1471.
-
(2008)
Arch Neurol
, vol.65
, pp. 1467-1471
-
-
Roe, C.M.1
Mintun, M.A.2
D'Angelo, G.3
Xiong, C.4
Grant, E.A.5
Morris, J.C.6
-
77
-
-
84871972979
-
Effect of lifestyle activities on Alzheimer disease biomarkers and cognition
-
Vemuri, P., Lesnick, T.G., Przybelski, S.A., Knopman, D.S., Roberts, R.O., Lowe, V.J., Kantarci, K., Senjem, M.L., Gunter, J.L., Boeve, B.F., Petersen, R.C., Jack, C.R. Jr., Effect of lifestyle activities on Alzheimer disease biomarkers and cognition. Ann Neurol 72 (2012), 730–738.
-
(2012)
Ann Neurol
, vol.72
, pp. 730-738
-
-
Vemuri, P.1
Lesnick, T.G.2
Przybelski, S.A.3
Knopman, D.S.4
Roberts, R.O.5
Lowe, V.J.6
Kantarci, K.7
Senjem, M.L.8
Gunter, J.L.9
Boeve, B.F.10
Petersen, R.C.11
Jack, C.R.12
-
78
-
-
39049170344
-
Cognitive reserve hypothesis: Pittsburgh Compound B and fluorodeoxyglucose positron emission tomography in relation to education in mild Alzheimer's disease
-
Kemppainen, N.M., Aalto, S., Karrasch, M., Nagren, K., Savisto, N., Oikonen, V., Viitanen, M., Parkkola, R., Rinne, J.O., Cognitive reserve hypothesis: Pittsburgh Compound B and fluorodeoxyglucose positron emission tomography in relation to education in mild Alzheimer's disease. Ann Neurol 63 (2008), 112–118.
-
(2008)
Ann Neurol
, vol.63
, pp. 112-118
-
-
Kemppainen, N.M.1
Aalto, S.2
Karrasch, M.3
Nagren, K.4
Savisto, N.5
Oikonen, V.6
Viitanen, M.7
Parkkola, R.8
Rinne, J.O.9
-
79
-
-
84905867828
-
Neuropsychological changes in asymptomatic persons with Alzheimer disease neuropathology
-
Monsell, S.E., Mock, C., Hassenstab, J., Roe, C.M., Cairns, N.J., Morris, J.C., Kukull, W., Neuropsychological changes in asymptomatic persons with Alzheimer disease neuropathology. Neurology 83 (2014), 434–440.
-
(2014)
Neurology
, vol.83
, pp. 434-440
-
-
Monsell, S.E.1
Mock, C.2
Hassenstab, J.3
Roe, C.M.4
Cairns, N.J.5
Morris, J.C.6
Kukull, W.7
-
80
-
-
84927173827
-
Abeta and cognitive change: examining the preclinical and prodromal stages of Alzheimer's disease
-
Lim, Y.Y., Maruff, P., Pietrzak, R.H., Ellis, K.A., Darby, D., Ames, D., Harrington, K., Martins, R.N., Masters, C.L., Szoeke, C., Savage, G., Villemagne, V.L., Rowe, C.C., Abeta and cognitive change: examining the preclinical and prodromal stages of Alzheimer's disease. Alzheimers Dement 10 (2014), 743–751.e1.
-
(2014)
Alzheimers Dement
, vol.10
, pp. 743-751.e1
-
-
Lim, Y.Y.1
Maruff, P.2
Pietrzak, R.H.3
Ellis, K.A.4
Darby, D.5
Ames, D.6
Harrington, K.7
Martins, R.N.8
Masters, C.L.9
Szoeke, C.10
Savage, G.11
Villemagne, V.L.12
Rowe, C.C.13
-
81
-
-
84870503989
-
Amyloid deposition detected with florbetapir F 18 ((18)F-AV-45) is related to lower episodic memory performance in clinically normal older individuals
-
Sperling, R.A., Johnson, K.A., Doraiswamy, P.M., Reiman, E.M., Fleisher, A.S., Sabbagh, M.N., Sadowsky, C.H., Carpenter, A., Davis, M.D., Lu, M., Flitter, M., Joshi, A.D., Clark, C.M., Grundman, M., Mintun, M.A., Skovronsky, D.M., Pontecorvo, M.J., AV45-A05 Study Group. Amyloid deposition detected with florbetapir F 18 ((18)F-AV-45) is related to lower episodic memory performance in clinically normal older individuals. Neurobiol Aging 34 (2013), 822–831.
-
(2013)
Neurobiol Aging
, vol.34
, pp. 822-831
-
-
Sperling, R.A.1
Johnson, K.A.2
Doraiswamy, P.M.3
Reiman, E.M.4
Fleisher, A.S.5
Sabbagh, M.N.6
Sadowsky, C.H.7
Carpenter, A.8
Davis, M.D.9
Lu, M.10
Flitter, M.11
Joshi, A.D.12
Clark, C.M.13
Grundman, M.14
Mintun, M.A.15
Skovronsky, D.M.16
Pontecorvo, M.J.17
-
82
-
-
79960199327
-
Cognition and beta-amyloid in preclinical Alzheimer's disease: data from the AIBL study
-
Pike, K.E., Ellis, K.A., Villemagne, V.L., Good, N., Chetelat, G., Ames, D., Szoeke, C., Laws, S.M., Verdile, G., Martins, R.N., Masters, C.L., Rowe, C.C., Cognition and beta-amyloid in preclinical Alzheimer's disease: data from the AIBL study. Neuropsychologia 49 (2011), 2384–2390.
-
(2011)
Neuropsychologia
, vol.49
, pp. 2384-2390
-
-
Pike, K.E.1
Ellis, K.A.2
Villemagne, V.L.3
Good, N.4
Chetelat, G.5
Ames, D.6
Szoeke, C.7
Laws, S.M.8
Verdile, G.9
Martins, R.N.10
Masters, C.L.11
Rowe, C.C.12
-
83
-
-
35648932901
-
Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease
-
Pike, K.E., Savage, G., Villemagne, V.L., Ng, S., Moss, S.A., Maruff, P., Mathis, C.A., Klunk, W.E., Masters, C.L., Rowe, C.C., Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease. Brain 130 (2007), 2837–2844.
-
(2007)
Brain
, vol.130
, pp. 2837-2844
-
-
Pike, K.E.1
Savage, G.2
Villemagne, V.L.3
Ng, S.4
Moss, S.A.5
Maruff, P.6
Mathis, C.A.7
Klunk, W.E.8
Masters, C.L.9
Rowe, C.C.10
-
84
-
-
84904258819
-
Impairments in experience-dependent scaling and stability of hippocampal place fields limit spatial learning in a mouse model of Alzheimer's disease
-
Zhao, R., Fowler, S.W., Chiang, A.C., Ji, D., Jankowsky, J.L., Impairments in experience-dependent scaling and stability of hippocampal place fields limit spatial learning in a mouse model of Alzheimer's disease. Hippocampus 24 (2014), 963–978.
-
(2014)
Hippocampus
, vol.24
, pp. 963-978
-
-
Zhao, R.1
Fowler, S.W.2
Chiang, A.C.3
Ji, D.4
Jankowsky, J.L.5
-
85
-
-
84874605021
-
Reversible pathologic and cognitive phenotypes in an inducible model of Alzheimer-amyloidosis
-
Melnikova, T., Fromholt, S., Kim, H., Lee, D., Xu, G., Price, A., Moore, B.D., Golde, T.E., Felsenstein, K.M., Savonenko, A., Borchelt, D.R., Reversible pathologic and cognitive phenotypes in an inducible model of Alzheimer-amyloidosis. J Neurosci 33 (2013), 3765–3779.
-
(2013)
J Neurosci
, vol.33
, pp. 3765-3779
-
-
Melnikova, T.1
Fromholt, S.2
Kim, H.3
Lee, D.4
Xu, G.5
Price, A.6
Moore, B.D.7
Golde, T.E.8
Felsenstein, K.M.9
Savonenko, A.10
Borchelt, D.R.11
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