Impairments in experience-dependent scaling and stability of hippocampal place fields limit spatial learning in a mouse model of Alzheimer's disease

Hippocampus

Volumn 24, Issue 8, 2014, Pages 963-978

  Zhao, Rong ^a   Fowler, Stephanie W ^a   Chiang, Angie C A ^a   Ji, Daoyun ^a   Jankowsky, Joanna L ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Amyloid; CA1; Cognitive decline; Hippocampal place cell; Spatial tuning

Indexed keywords

AMYLOID PRECURSOR PROTEIN;

ACCURACY; ALZHEIMER DISEASE; AMYLOIDOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN DISEASE; CELL LEVEL; COGNITIVE DEFECT; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; HIPPOCAMPUS; MALE; MORRIS WATER MAZE TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; RELIABILITY; SPATIAL LEARNING; TRANSGENIC ORGANISM; ACTION POTENTIAL; ANIMAL; C57BL MOUSE; DISEASE MODEL; ELECTRODE IMPLANT; ENVIRONMENT; MAZE TEST; NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; SPATIAL ORIENTATION; TRANSGENIC MOUSE;

ACTION POTENTIALS; ALZHEIMER DISEASE; AMYLOIDOSIS; ANIMALS; DISEASE MODELS, ANIMAL; ELECTRODES, IMPLANTED; ENVIRONMENT; FEMALE; HIPPOCAMPUS; MALE; MAZE LEARNING; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONS; SPATIAL LEARNING; SPATIAL NAVIGATION;

EID: 84904258819     PISSN: 10509631     EISSN: 10981063     Source Type: Journal    
DOI: 10.1002/hipo.22283     Document Type: Article

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