-
1
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
DOI 10.1126/science.1072994
-
Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002;297:353-356. (Pubitemid 34790756)
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
2
-
-
0032989712
-
Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease
-
Price JL, Morris JC. Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease Ann Neurol 1999;45:358 -368.
-
(1999)
Ann Neurol
, vol.45
, pp. 358-368
-
-
Price, J.L.1
Morris, J.C.2
-
3
-
-
33745876233
-
Neuropathology of older persons without cognitive impairment from two community-based studies
-
Bennett D, Schneider J, Arvanitakis Z, et al. Neuropathology of older persons without cognitive impairment from two community-based studies. Neurology 2006;66:1837.
-
(2006)
Neurology
, vol.66
, pp. 1837
-
-
Bennett, D.1
Schneider, J.2
Arvanitakis, Z.3
-
4
-
-
66549106850
-
Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: Implications for sequence of pathological events in Alzheimer's disease
-
Jack CR, Jr., Lowe VJ, Weigand SD, et al. Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease. Brain 2009;132:1355-1365.
-
(2009)
Brain
, vol.132
, pp. 1355-1365
-
-
Jack Jr., C.R.1
Lowe, V.J.2
Weigand, S.D.3
-
6
-
-
33747048954
-
11C]PIB in a nondemented population: Potential antecedent marker of Alzheimer disease
-
DOI 10.1212/01.wnl.0000228230.26044.a4, PII 0000611420060808000020
-
Mintun MA, Larossa GN, Sheline YI, et al. [11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease. Neurology 2006;67:446-452. (Pubitemid 44214969)
-
(2006)
Neurology
, vol.67
, Issue.3
, pp. 446-452
-
-
Mintun, M.A.1
Larossa, G.N.2
Sheline, Y.I.3
Dence, C.S.4
Lee, S.Y.5
MacH, R.H.6
Klunk, W.E.7
Mathis, C.A.8
Dekosky, S.T.9
Morris, J.C.10
-
7
-
-
39749108812
-
11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment
-
Jack CR, Jr., Lowe VJ, Senjem ML, et al. 11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment. Brain 2008;131:665- 680.
-
(2008)
Brain
, vol.131
, pp. 665-680
-
-
Jack Jr., C.R.1
Lowe, V.J.2
Senjem, M.L.3
-
8
-
-
77649314191
-
APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging
-
Morris JC, Roe CM, Xiong C, et al. APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging. Ann Neurol 2010;67:122-131.
-
(2010)
Ann Neurol
, vol.67
, pp. 122-131
-
-
Morris, J.C.1
Roe, C.M.2
Xiong, C.3
-
9
-
-
66149084048
-
Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease
-
Reiman EM, Chen K, Liu X, et al. Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease. Proc Natl Acad Sci USA 2009;106:6820-6825.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 6820-6825
-
-
Reiman, E.M.1
Chen, K.2
Liu, X.3
-
10
-
-
77954033257
-
Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging
-
Rowe CC, Ellis KA, Rimajova M, et al. Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging. Neurobiol Aging 2010;31: 1275-1283.
-
(2010)
Neurobiol Aging
, vol.31
, pp. 1275-1283
-
-
Rowe, C.C.1
Ellis, K.A.2
Rimajova, M.3
-
11
-
-
73549106106
-
Cognitive decline and brain volume loss as signatures of cerebral amyloid-beta peptide deposition identified with Pittsburgh compound B: Cognitive decline associated with Abeta deposition
-
Storandt M, Mintun MA, Head D, Morris JC. Cognitive decline and brain volume loss as signatures of cerebral amyloid-beta peptide deposition identified with Pittsburgh compound B: cognitive decline associated with Abeta deposition. Arch Neurol 2009;66:1476 -1481.
-
(2009)
Arch Neurol
, vol.66
, pp. 1476-1481
-
-
Storandt, M.1
Mintun, M.A.2
Head, D.3
Morris, J.C.4
-
12
-
-
43849084404
-
A [beta] deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease
-
Villemagne V, Pike K, Darby D, et al. A [beta] deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease. Neuropsychologia 2008;46:1688 -1697.
-
(2008)
Neuropsychologia
, vol.46
, pp. 1688-1697
-
-
Villemagne, V.1
Pike, K.2
Darby, D.3
-
13
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder EH, Saunders AM, Strittmatter WJ, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993;261:921-923. (Pubitemid 23275809)
-
(1993)
Science
, vol.261
, Issue.5123
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
14
-
-
55949117032
-
Frequent amyloid deposition without significant cognitive impairment among the elderly
-
Aizenstein HJ, Nebes RD, Saxton JA, et al. Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol 2008;65:1509-1517.
-
(2008)
Arch Neurol
, vol.65
, pp. 1509-1517
-
-
Aizenstein, H.J.1
Nebes, R.D.2
Saxton, J.A.3
-
15
-
-
75649106499
-
Beta-amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia
-
Bourgeat P, Chetelat G, Villemagne VL, et al. Beta-amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia. Neurology 2010;74:121-127.
-
(2010)
Neurology
, vol.74
, pp. 121-127
-
-
Bourgeat, P.1
Chetelat, G.2
Villemagne, V.L.3
-
16
-
-
70349876480
-
Disruption of functional connectivity in clinically normal older adults harboring amyloid burden
-
Hedden T, Van Dijk KR, Becker JA, et al. Disruption of functional connectivity in clinically normal older adults harboring amyloid burden. J Neurosci 2009;29:12686-12694.
-
(2009)
J Neurosci
, vol.29
, pp. 12686-12694
-
-
Hedden, T.1
Van Dijk, K.R.2
Becker, J.A.3
-
17
-
-
78650222201
-
β-Amyloid affects frontal and posterior brain networks in normal aging
-
Oh H, Mormino EC, Madison C, Hayenga A, Smiljic A, Jagust WJ. β-Amyloid affects frontal and posterior brain networks in normal aging. Neuroimage 2011;54:1887-1895.
-
(2011)
Neuroimage
, vol.54
, pp. 1887-1895
-
-
Oh, H.1
Mormino, E.C.2
Madison, C.3
Hayenga, A.4
Smiljic, A.5
Jagust, W.J.6
-
18
-
-
66549127860
-
Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects
-
Mormino EC, Kluth JT, Madison CM, et al. Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects. Brain 2009;132:1310-1323.
-
(2009)
Brain
, vol.132
, pp. 1310-1323
-
-
Mormino, E.C.1
Kluth, J.T.2
Madison, C.M.3
-
19
-
-
35648932901
-
Beta-amyloid imaging and memory in non-demented individuals: Evidence for preclinical Alzheimer's disease
-
DOI 10.1093/brain/awm238
-
Pike KE, Savage G, Villemagne VL, et al. Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease. Brain 2007;130:2837-2844. (Pubitemid 350033975)
-
(2007)
Brain
, vol.130
, Issue.11
, pp. 2837-2844
-
-
Pike, K.E.1
Savage, G.2
Villemagne, V.L.3
Ng, S.4
Moss, S.A.5
Maruff, P.6
Mathis, C.A.7
Klunk, W.E.8
Masters, C.L.9
Rowe, C.C.10
-
20
-
-
77950538370
-
Cognition, reserve, and amyloid deposition in normal aging
-
Rentz DM, Locascio JJ, Becker JA, et al. Cognition, reserve, and amyloid deposition in normal aging. Ann Neurol 2010;67:353-364.
-
(2010)
Ann Neurol
, vol.67
, pp. 353-364
-
-
Rentz, D.M.1
Locascio, J.J.2
Becker, J.A.3
-
21
-
-
77949408552
-
Longitudinal cognitive decline is associated with fibrillar amyloid-beta measured by [11C]PiB
-
Resnick SM, Sojkova J, Zhou Y, et al. Longitudinal cognitive decline is associated with fibrillar amyloid-beta measured by [11C]PiB. Neurology 2010;74:807- 815.
-
(2010)
Neurology
, vol.74
, pp. 807-815
-
-
Resnick, S.M.1
Sojkova, J.2
Zhou, Y.3
-
22
-
-
79956098248
-
Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging and the Alzheimer's Association workgroup
-
Sperling RA, Aisen PS, Beckett LA, et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging and the Alzheimer's Association workgroup. Alzheimers Dement 2011;7:280-292.
-
(2011)
Alzheimers Dement
, vol.7
, pp. 280-292
-
-
Sperling, R.A.1
Aisen, P.S.2
Beckett, L.A.3
-
23
-
-
0016823810
-
"Mini-mental state": A practical method for grading the cognitive state of patients for the clinician
-
Folstein MF, Folstein SE, McHugh PR. "Mini-mental state": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-198.
-
(1975)
J Psychiatr Res
, vol.12
, pp. 189-198
-
-
Folstein, M.F.1
Folstein, S.E.2
McHugh, P.R.3
-
24
-
-
0024284028
-
A simple salting out procedure for extracting DNA from human nucleated cells
-
Miller S, Dykes D, Polesky H. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16:1215.
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 1215
-
-
Miller, S.1
Dykes, D.2
Polesky, H.3
-
25
-
-
0036915402
-
TaqMan systems for genotyping of disease-related polymorphisms present in the gene encoding apolipoprotein E
-
DOI 10.1515/CCLM.2002.197
-
Koch W, Ehrenhaft A, Griesser K, et al. TaqMan systems for genotyping of disease-related polymorphisms present in the gene encoding apolipoprotein E. Clin Chem Lab Med 2002;40:1123-1131. (Pubitemid 36032659)
-
(2002)
Clinical Chemistry and Laboratory Medicine
, vol.40
, Issue.11
, pp. 1123-1131
-
-
Koch, W.1
Ehrenhaft, A.2
Griesser, K.3
Pfeufer, A.4
Muller, J.5
Schomig, A.6
Kastrati, A.7
-
26
-
-
58149206091
-
Decomposing adult age-differences in working memory
-
Salthouse T, Babcock R. Decomposing adult age-differences in working memory. Dev Psychol 1991;27:763-776.
-
(1991)
Dev Psychol
, vol.27
, pp. 763-776
-
-
Salthouse, T.1
Babcock, R.2
-
28
-
-
33847039693
-
Is working memory capacity task dependent?
-
Turner M, Engler R. Is working memory capacity task dependent? J Memory Lang 1989;28:127-154.
-
(1989)
J Memory Lang
, vol.28
, pp. 127-154
-
-
Turner, M.1
Engler, R.2
-
29
-
-
0025890255
-
The Hopkins Verbal Learning Test: Development of a new memory test with six equivalent forms
-
Brandt J. The Hopkins Verbal Learning Test: development of a new memory test with six equivalent forms. Clin Neuropsychol 1991;5:125-142.
-
(1991)
Clin Neuropsychol
, vol.5
, pp. 125-142
-
-
Brandt, J.1
-
30
-
-
0028092805
-
Cambridge Neuropsychological Test Automated Battery (CANTAB): A factor analytic study of a large sample of normal elderly volunteers
-
Robbins T, James M, Owen A, Sahakian B, McInnes L, Rabbitt P. Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers. Dement Geriatr Cogn Disord 1994;5:266 -281.
-
(1994)
Dement Geriatr Cogn Disord
, vol.5
, pp. 266-281
-
-
Robbins, T.1
James, M.2
Owen, A.3
Sahakian, B.4
McInnes, L.5
Rabbitt, P.6
-
34
-
-
78751546481
-
Use of florbetapir-PET for imaging beta-amyloid pathology
-
Clark CM, Schneider JA, Bedell BJ, et al. Use of florbetapir-PET for imaging beta-amyloid pathology. JAMA 2011;305:275-283.
-
(2011)
JAMA
, vol.305
, pp. 275-283
-
-
Clark, C.M.1
Schneider, J.A.2
Bedell, B.J.3
-
35
-
-
0030805991
-
Frequency of stages of Alzheimer-related lesions in different age categories
-
DOI 10.1016/S0197-4580(97)00056-0, PII S0197458097000560
-
Braak H, Braak E. Frequency of stages of Alzheimer-related lesions in different age categories. Neurobiol Aging 1997;18:351-357. (Pubitemid 27435070)
-
(1997)
Neurobiology of Aging
, vol.18
, Issue.4
, pp. 351-357
-
-
Braak, H.1
Braak, E.2
-
36
-
-
67349184808
-
Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease
-
Price JL, McKeel DW, Jr., Buckles VD, et al. Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease. Neurobiol Aging 2009;30:1026-1036.
-
(2009)
Neurobiol Aging
, vol.30
, pp. 1026-1036
-
-
Price, J.L.1
McKeel Jr., D.W.2
Buckles, V.D.3
-
37
-
-
0024299370
-
Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
-
Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 1988;240:622-630.
-
(1988)
Science
, vol.240
, pp. 622-630
-
-
Mahley, R.W.1
-
38
-
-
78049467441
-
Larger temporal volume in elderly with high versus low beta-amyloid deposition
-
Chételat G, Villemagne VL, Pike KE, et al. Larger temporal volume in elderly with high versus low beta-amyloid deposition. Brain 2010;133:3349-3358.
-
(2010)
Brain
, vol.133
, pp. 3349-3358
-
-
Chételat, G.1
Villemagne, V.L.2
Pike, K.E.3
-
39
-
-
38149081191
-
Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: Proof of mechanism
-
Rowe CC, Ackerman U, Browne W, et al. Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism. Lancet Neurol 2008;7:129-135.
-
(2008)
Lancet Neurol
, vol.7
, pp. 129-135
-
-
Rowe, C.C.1
Ackerman, U.2
Browne, W.3
-
40
-
-
67650875899
-
Amyloid deposition is associated with impaired default network function in older persons without dementia
-
Sperling RA, Laviolette PS, O'Keefe K, et al. Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron 2009;63:178-188.
-
(2009)
Neuron
, vol.63
, pp. 178-188
-
-
Sperling, R.A.1
Laviolette, P.S.2
O'Keefe, K.3
|