-
1
-
-
84928023485
-
Clostridium difficile infection
-
Leffler, D. A. & Lamont, J. T. Clostridium difficile infection. N. Engl. J. Med. 372, 1539-1548 (2015).
-
(2015)
N. Engl. J. Med.
, vol.372
, pp. 1539-1548
-
-
Leffler, D.A.1
Lamont, J.T.2
-
2
-
-
85014277530
-
Clostridium difficile disease: Diagnosis, pathogenesis, and treatment update
-
Napolitano, L. M. & Edmiston, C. E. Jr. Clostridium difficile disease: diagnosis, pathogenesis, and treatment update. Surgery 162, 325-348 (2017).
-
(2017)
Surgery
, vol.162
, pp. 325-348
-
-
Napolitano, L.M.1
Edmiston, C.E.2
-
4
-
-
84863676446
-
Current status of Clostridium difficile infection epidemiology
-
Lessa, F. C., Gould, C. V. & McDonald, L. C. Current status of Clostridium difficile infection epidemiology. Clin. Infect. Dis. 55(Suppl. 2), S65-S70 (2012).
-
(2012)
Clin. Infect. Dis.
, vol.55
, pp. S65-S70
-
-
Lessa, F.C.1
Gould, C.V.2
McDonald, L.C.3
-
5
-
-
77951026738
-
Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA)
-
Cohen, S. H. et al. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect. Control Hosp. Epidemiol. 31, 431-455 (2010).
-
(2010)
Infect. Control Hosp. Epidemiol.
, vol.31
, pp. 431-455
-
-
Cohen, S.H.1
-
6
-
-
70649107673
-
European Society of Clinical Microbiology and Infectious Diseases (ESCMID): Treatment guidance document for Clostridium difficile infection (CDI)
-
Bauer, M. P., Kuijper, E. J. & van Dissel, J. T. European Society of Clinical Microbiology and Infectious Diseases (ESCMID): treatment guidance document for Clostridium difficile infection (CDI). Clin. Microbiol. Infect. 15, 1067-1079 (2009).
-
(2009)
Clin. Microbiol. Infect.
, vol.15
, pp. 1067-1079
-
-
Bauer, M.P.1
Kuijper, E.J.2
Van Dissel, J.T.3
-
7
-
-
84887259304
-
European Society of Clinical Microbiology and Infectious Diseases: Update of the treatment guidance document for Clostridium difficile infection
-
Debast, S. B., Bauer, M. P. & Kuijper, E. J. European Society of Clinical Microbiology and Infectious Diseases: update of the treatment guidance document for Clostridium difficile infection. Clin. Microbiol. Infect. 20(Suppl. 2), 1-26 (2014).
-
(2014)
Clin. Microbiol. Infect.
, vol.20
, pp. 1-26
-
-
Debast, S.B.1
Bauer, M.P.2
Kuijper, E.J.3
-
8
-
-
84964493540
-
Recent advances in the understanding of antibiotic resistance in Clostridium difficile infection
-
Spigaglia, P. Recent advances in the understanding of antibiotic resistance in Clostridium difficile infection. Ther. Adv. Infect. Dis. 3, 23-42 (2016).
-
(2016)
Ther. Adv. Infect. Dis.
, vol.3
, pp. 23-42
-
-
Spigaglia, P.1
-
9
-
-
85021267374
-
Update on antimicrobial resistance in Clostridium difficile: Resistance mechanisms and antimicrobial susceptibility testing
-
Peng, Z. et al. Update on antimicrobial resistance in Clostridium difficile: resistance mechanisms and antimicrobial susceptibility testing. J. Clin. Microbiol. 55, 1998-2008 (2017).
-
(2017)
J. Clin. Microbiol.
, vol.55
, pp. 1998-2008
-
-
Peng, Z.1
-
10
-
-
84979016970
-
European Society of Clinical Microbiology and Infectious Diseases: Update of the diagnostic guidance document for Clostridium difficile infection
-
Crobach, M. J. et al European Society of Clinical Microbiology and Infectious Diseases: update of the diagnostic guidance document for Clostridium difficile infection. Clin. Microbiol. Infect. 22(Suppl. 4), S63-S81 (2016).
-
(2016)
Clin. Microbiol. Infect.
, vol.22
, pp. S63-S81
-
-
Crobach, M.J.1
-
11
-
-
84952324895
-
Diagnosis and treatment of Clostridium difficile infection
-
Gerding, D. N., File, T. M. Jr & McDonald, L. C. Diagnosis and treatment of Clostridium difficile infection. Infect. Dis. Clin. Pract. 24, 3-10 (2016).
-
(2016)
Infect. Dis. Clin. Pract.
, vol.24
, pp. 3-10
-
-
Gerding, D.N.1
File, T.M.2
McDonald, L.C.3
-
12
-
-
80053253206
-
Biology of Clostridium difficile: Implications for epidemiology and diagnosis
-
Carroll, K. C. & Bartlett, J. G. Biology of Clostridium difficile: implications for epidemiology and diagnosis. Annu. Rev. Microbiol. 65, 501-521 (2011).
-
(2011)
Annu. Rev. Microbiol.
, vol.65
, pp. 501-521
-
-
Carroll, K.C.1
Bartlett, J.G.2
-
13
-
-
84897005021
-
Real-time cellular analysis coupled with a specimen enrichment accurately detects and quantifies Clostridium difficile toxins in stool
-
Huang, B. et al. Real-time cellular analysis coupled with a specimen enrichment accurately detects and quantifies Clostridium difficile toxins in stool. J. Clin. Microbiol. 52, 1105-1111 (2014).
-
(2014)
J. Clin. Microbiol.
, vol.52
, pp. 1105-1111
-
-
Huang, B.1
-
14
-
-
85014406448
-
Molecular epidemiology of Clostridium difficile infection in hospitalized patients in Eastern China
-
Jin, D. et al. Molecular epidemiology of Clostridium difficile infection in hospitalized patients in Eastern China. J. Clin. Microbiol. 55, 801-810 (2017).
-
(2017)
J. Clin. Microbiol.
, vol.55
, pp. 801-810
-
-
Jin, D.1
-
15
-
-
52249111798
-
Application of isothermal helicase-dependent amplification with a disposable detection device in a simple sensitive stool test for toxigenic Clostridium difficile
-
Chow, W. H. et al. Application of isothermal helicase-dependent amplification with a disposable detection device in a simple sensitive stool test for toxigenic Clostridium difficile. J. Mol. Diagn. 10, 452-458 (2008).
-
(2008)
J. Mol. Diagn.
, vol.10
, pp. 452-458
-
-
Chow, W.H.1
-
16
-
-
78049517380
-
Assessment of Clostridium difficile infections by quantitative detection of tcdB toxin by use of a real-time cell analysis system
-
Ryder, A. B. et al. Assessment of Clostridium difficile infections by quantitative detection of tcdB toxin by use of a real-time cell analysis system. J. Clin. Microbiol. 48, 4129-4134 (2010).
-
(2010)
J. Clin. Microbiol.
, vol.48
, pp. 4129-4134
-
-
Ryder, A.B.1
-
17
-
-
84982307153
-
False negative results in Clostridium difficile testing
-
Murad, Y. M. et al. False negative results in Clostridium difficile testing. BMC Infect. Dis. 16, 430 (2016).
-
(2016)
BMC Infect. Dis.
, vol.16
, pp. 430
-
-
Murad, Y.M.1
-
18
-
-
0028265436
-
Comparison of four commercially available rapid enzyme immunoassays with cytotoxin assay for detection of Clostridium difficile toxin(s) from stool specimens
-
Merz, C. S. et al. Comparison of four commercially available rapid enzyme immunoassays with cytotoxin assay for detection of Clostridium difficile toxin(s) from stool specimens. J. Clin. Microbiol. 32, 1142-1147 (1994).
-
(1994)
J. Clin. Microbiol.
, vol.32
, pp. 1142-1147
-
-
Merz, C.S.1
-
19
-
-
85018270569
-
Strategies for optimizing the diagnostic predictive value of Clostridium difficile molecular diagnostics
-
Kociolek, L. K. Strategies for optimizing the diagnostic predictive value of Clostridium difficile molecular diagnostics. J. Clin. Microbiol. 55, 1244-1248 (2017).
-
(2017)
J. Clin. Microbiol.
, vol.55
, pp. 1244-1248
-
-
Kociolek, L.K.1
-
20
-
-
84922930416
-
Diagnostic pitfalls in Clostridium difficile infection
-
Planche, T. & Wilcox, M. H. Diagnostic pitfalls in Clostridium difficile infection. Infect. Dis. Clin. North Am. 29, 63-82 (2015).
-
(2015)
Infect. Dis. Clin. North Am.
, vol.29
, pp. 63-82
-
-
Planche, T.1
Wilcox, M.H.2
-
21
-
-
84892481574
-
Does a rapid diagnosis of Clostridium difficile infection impact on quality of patient management?
-
Barbut, F. et al. Does a rapid diagnosis of Clostridium difficile infection impact on quality of patient management? Clin. Microbiol. Infect. 20, 136-144 (2014).
-
(2014)
Clin. Microbiol. Infect.
, vol.20
, pp. 136-144
-
-
Barbut, F.1
-
22
-
-
85017376088
-
Clostridium difficile and cystic fibrosis: Management strategies and the role of faecal transplantation
-
Dunwoody, R., Steel, A., Landy, J. & Simmonds, N. Clostridium difficile and cystic fibrosis: management strategies and the role of faecal transplantation. Paediatr. Respir. Rev. doi:10.1016/j.prrv.2017.03.003 (2017).
-
(2017)
Paediatr. Respir. Rev
-
-
Dunwoody, R.1
Steel, A.2
Landy, J.3
Simmonds, N.4
-
23
-
-
84879764131
-
Diagnosis of Clostridium difficile infection: An ongoing conundrum for clinicians and for clinical laboratories
-
Burnham, C. A. & Carroll, K. C. Diagnosis of Clostridium difficile infection: an ongoing conundrum for clinicians and for clinical laboratories. Clin. Microbiol. Rev. 26, 604-630 (2013).
-
(2013)
Clin. Microbiol. Rev.
, vol.26
, pp. 604-630
-
-
Burnham, C.A.1
Carroll, K.C.2
-
24
-
-
84875952150
-
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections
-
Surawicz, C. M. et al Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections. Am. J. Gastroenterol. 108, 478-498 (2013).
-
(2013)
Am. J. Gastroenterol.
, vol.108
, pp. 478-498
-
-
Surawicz, C.M.1
-
25
-
-
84893038141
-
Economic evaluation of laboratory testing strategies for hospital-associated Clostridium difficile infection
-
Schroeder, L. F., Robilotti, E., Peterson, L. R., Banaei, N. & Dowdy, D. W. Economic evaluation of laboratory testing strategies for hospital-associated Clostridium difficile infection. J. Clin. Microbiol. 52, 489-496 (2014).
-
(2014)
J. Clin. Microbiol.
, vol.52
, pp. 489-496
-
-
Schroeder, L.F.1
Robilotti, E.2
Peterson, L.R.3
Banaei, N.4
Dowdy, D.W.5
-
26
-
-
84986271699
-
Rapid detection of Clostridium difficile toxins and laboratory diagnosis of Clostridium difficile infections
-
Chen, S., Gu, H., Sun, C., Wang, H. & Wang, J. Rapid detection of Clostridium difficile toxins and laboratory diagnosis of Clostridium difficile infections. Infection 45, 255-262 (2017).
-
(2017)
Infection
, vol.45
, pp. 255-262
-
-
Chen, S.1
Gu, H.2
Sun, C.3
Wang, H.4
Wang, J.5
-
27
-
-
84891773348
-
Clostridium difficile binary toxin CDT: Mechanism, epidemiology, and potential clinical importance
-
Gerding, D. N., Johnson, S., Rupnik, M. & Aktories, K. Clostridium difficile binary toxin CDT: mechanism, epidemiology, and potential clinical importance. Gut Microbes 5, 15-27 (2014).
-
(2014)
Gut Microbes
, vol.5
, pp. 15-27
-
-
Gerding, D.N.1
Johnson, S.2
Rupnik, M.3
Aktories, K.4
-
28
-
-
84929949214
-
Optimizing the laboratory diagnosis of Clostridium difficile infection
-
Gilligan, P. H. Optimizing the laboratory diagnosis of Clostridium difficile infection. Clin. Lab. Med. 35, 299-312 (2015).
-
(2015)
Clin. Lab. Med.
, vol.35
, pp. 299-312
-
-
Gilligan, P.H.1
-
29
-
-
84988685711
-
Clostridium difficile infection
-
Smits, W. K., Lyras, D., Lacy, D. B., Wilcox, M. H. & Kuijper, E. J. Clostridium difficile infection. Nat. Rev. Dis. Primers 2, 16020 (2016).
-
(2016)
Nat. Rev. Dis. Primers
, vol.2
, pp. 16020
-
-
Smits, W.K.1
Lyras, D.2
Lacy, D.B.3
Wilcox, M.H.4
Kuijper, E.J.5
-
30
-
-
85014957871
-
Current knowledge on the laboratory diagnosis of Clostridium difficile infection
-
Martinez-Melendez, A. et al. Current knowledge on the laboratory diagnosis of Clostridium difficile infection. World J. Gastroenterol. 23, 1552-1567 (2017).
-
(2017)
World J. Gastroenterol.
, vol.23
, pp. 1552-1567
-
-
Martinez-Melendez, A.1
-
31
-
-
80052444456
-
Diagnostic accuracy of real-time polymerase chain reaction in detection of Clostridium difficile in the stool samples of patients with suspected Clostridium difficile Infection: A meta-analysis
-
Deshpande, A. et al. Diagnostic accuracy of real-time polymerase chain reaction in detection of Clostridium difficile in the stool samples of patients with suspected Clostridium difficile Infection: a meta-analysis. Clin. Infect. Dis. 53, e81-e90 (2011).
-
(2011)
Clin. Infect. Dis.
, vol.53
, pp. e81-e90
-
-
Deshpande, A.1
-
32
-
-
84923052479
-
How well does physician selection of microbiologic tests identify Clostridium difficile and other pathogens in paediatric diarrhoea? Insights using multiplex PCR-based detection
-
Stockmann, C. et al. How well does physician selection of microbiologic tests identify Clostridium difficile and other pathogens in paediatric diarrhoea? Insights using multiplex PCR-based detection. Clin. Microbiol. Infect. 21, 179.e9-179. e15. (2015).
-
(2015)
Clin. Microbiol. Infect.
, vol.21
, pp. 179e9-179e15
-
-
Stockmann, C.1
-
33
-
-
84939874210
-
Gastrointestinal pathogens detected by multiplex nucleic acid amplification testing in stools of pediatric patients and patients returning from the tropics
-
Beckmann, C., Heininger, U., Marti, H. & Hirsch, H. H. Gastrointestinal pathogens detected by multiplex nucleic acid amplification testing in stools of pediatric patients and patients returning from the tropics. Infection 42, 961-970 (2014).
-
(2014)
Infection
, vol.42
, pp. 961-970
-
-
Beckmann, C.1
Heininger, U.2
Marti, H.3
Hirsch, H.H.4
-
34
-
-
84869080321
-
Outcomes in patients tested for Clostridium difficile toxins
-
Polage, C. R. et al. Outcomes in patients tested for Clostridium difficile toxins. Diagn. Microbiol. Infect. Dis. 74, 369-373 (2012).
-
(2012)
Diagn. Microbiol. Infect. Dis.
, vol.74
, pp. 369-373
-
-
Polage, C.R.1
-
35
-
-
84946147732
-
Overdiagnosis of Clostridium difficile infection in the molecular test era
-
Polage, C. R. et al. Overdiagnosis of Clostridium difficile infection in the molecular test era. JAMA Intern. Med. 175, 1792-1801 (2015).
-
(2015)
JAMA Intern. Med.
, vol.175
, pp. 1792-1801
-
-
Polage, C.R.1
-
36
-
-
85014348543
-
Impact of a healthcare provider educational intervention on frequency of Clostridium difficile polymerase chain reaction testing in children: A segmented regression analysis
-
Kociolek, L. K. et al. Impact of a healthcare provider educational intervention on frequency of Clostridium difficile polymerase chain reaction testing in children: a segmented regression analysis. J. Pediatr. Infect. Dis. Soc. 6, 142-148 (2017).
-
(2017)
J. Pediatr. Infect. Dis. Soc.
, vol.6
, pp. 142-148
-
-
Kociolek, L.K.1
-
37
-
-
84872171026
-
Role of fecal Clostridium difficile load in discrepancies between toxin tests and PCR: Is quantitation the next step in C. Difficile testing?
-
Leslie, J. L., Cohen, S. H., Solnick, J. V. & Polage, C. R. Role of fecal Clostridium difficile load in discrepancies between toxin tests and PCR: is quantitation the next step in C. difficile testing?. Eur. J. Clin. Microbiol. Infect. Dis. 31, 3295-3299 (2012).
-
(2012)
Eur. J. Clin. Microbiol. Infect. Dis.
, vol.31
, pp. 3295-3299
-
-
Leslie, J.L.1
Cohen, S.H.2
Solnick, J.V.3
Polage, C.R.4
-
38
-
-
85018339961
-
Real-time electronic tracking of diarrheal episodes and laxative therapy enables verification of Clostridium difficile clinical testing criteria and reduction of Clostridium difficile infection rates
-
Truong, C. Y. et al. Real-time electronic tracking of diarrheal episodes and laxative therapy enables verification of Clostridium difficile clinical testing criteria and reduction of Clostridium difficile infection rates. J. Clin. Microbiol. 55, 1276-1284 (2017).
-
(2017)
J. Clin. Microbiol.
, vol.55
, pp. 1276-1284
-
-
Truong, C.Y.1
-
39
-
-
85028300056
-
Clostridium difficile PCR cycle threshold predicts free toxin
-
Senchyna, F. et al. Clostridium difficile PCR cycle threshold predicts free toxin. J. Clin. Microbiol. 55, 2651-2660 (2017).
-
(2017)
J. Clin. Microbiol.
, vol.55
, pp. 2651-2660
-
-
Senchyna, F.1
-
40
-
-
84964555274
-
Recent advances in the diagnosis and treatment of Clostridium difficile infection
-
Avila, M. B., Avila, N. P. & Dupont, A. W. Recent advances in the diagnosis and treatment of Clostridium difficile infection. F1000Research 5, https://doi.org/10.12688/f1000research.7109.1 (2016).
-
(2016)
F1000Research
, vol.5
-
-
Avila, M.B.1
Avila, N.P.2
Dupont, A.W.3
-
41
-
-
80053467680
-
Extended multilocus variable-number tandem-repeat analysis of Clostridium difficile correlates exactly with ribotyping and enables identification of hospital transmission
-
Manzoor, S. E. et al. Extended multilocus variable-number tandem-repeat analysis of Clostridium difficile correlates exactly with ribotyping and enables identification of hospital transmission. J. Clin. Microbiol. 49, 3523-3530 (2011).
-
(2011)
J. Clin. Microbiol.
, vol.49
, pp. 3523-3530
-
-
Manzoor, S.E.1
-
42
-
-
38949178833
-
Comparison of seven techniques for typing international epidemic strains of Clostridium difficile: Restriction endonuclease analysis, pulsed-field gel electrophoresis, PCR-ribotyping, multilocus sequence typing, multilocus variable-number tandem-repeat analysis, amplified fragment length polymorphism, and surface layer protein A gene sequence typing
-
Killgore, G. et al. Comparison of seven techniques for typing international epidemic strains of Clostridium difficile: restriction endonuclease analysis, pulsed-field gel electrophoresis, PCR-ribotyping, multilocus sequence typing, multilocus variable-number tandem-repeat analysis, amplified fragment length polymorphism, and surface layer protein A gene sequence typing. J. Clin. Microbiol. 46, 431-437 (2008).
-
(2008)
J. Clin. Microbiol.
, vol.46
, pp. 431-437
-
-
Killgore, G.1
-
43
-
-
27144504255
-
Multilocus sequence analysis and comparative evolution of virulence-associated genes and housekeeping genes of Clostridium difficile
-
Lemee, L. et al. Multilocus sequence analysis and comparative evolution of virulence-associated genes and housekeeping genes of Clostridium difficile. Microbiology 151, 3171-3180 (2005).
-
(2005)
Microbiology
, vol.151
, pp. 3171-3180
-
-
Lemee, L.1
-
44
-
-
2942594170
-
Multilocus sequence typing analysis of human and animal Clostridium difficile isolates of various toxigenic types
-
Lemee, L., Dhalluin, A., Pestel-Caron, M., Lemeland, J. F. & Pons, J. L. Multilocus sequence typing analysis of human and animal Clostridium difficile isolates of various toxigenic types. J. Clin. Microbiol. 42, 2609-2617 (2004).
-
(2004)
J. Clin. Microbiol.
, vol.42
, pp. 2609-2617
-
-
Lemee, L.1
Dhalluin, A.2
Pestel-Caron, M.3
Lemeland, J.F.4
Pons, J.L.5
-
45
-
-
33947195010
-
Typing and subtyping of Clostridium difficile isolates by using multiple-locus variable-number tandem-repeat analysis
-
van den Berg, R. J., Schaap, I., Templeton, K. E., Klaassen, C. H. & Kuijper, E. J. Typing and subtyping of Clostridium difficile isolates by using multiple-locus variable-number tandem-repeat analysis. J. Clin. Microbiol. 45, 1024-1028 (2007).
-
(2007)
J. Clin. Microbiol.
, vol.45
, pp. 1024-1028
-
-
Van Den Berg, R.J.1
Schaap, I.2
Templeton, K.E.3
Klaassen, C.H.4
Kuijper, E.J.5
-
46
-
-
84929512453
-
Sequencing and beyond: Integrating molecular 'omics' for microbial community profiling
-
Franzosa, E. A. et al. Sequencing and beyond: integrating molecular 'omics' for microbial community profiling. Nat. Rev. Microbiol. 13, 360-372 (2015).
-
(2015)
Nat. Rev. Microbiol.
, vol.13
, pp. 360-372
-
-
Franzosa, E.A.1
-
47
-
-
84871366407
-
Microevolutionary analysis of Clostridium difficile genomes to investigate transmission
-
Didelot, X. et al Microevolutionary analysis of Clostridium difficile genomes to investigate transmission. Genome Biol. 13, R118 (2012).
-
(2012)
Genome Biol.
, vol.13
, pp. R118
-
-
Didelot, X.1
-
48
-
-
84871990888
-
Emergence and global spread of epidemic healthcare-associated Clostridium difficile
-
He, M. et al. Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nat. Genet. 45, 109-113 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 109-113
-
-
He, M.1
-
49
-
-
84884510020
-
Diverse sources of C. Difficile infection identified on whole-genome sequencing
-
Eyre, D. W. et al. Diverse sources of C. difficile infection identified on whole-genome sequencing. N. Engl. J. Med. 369, 1195-1205 (2013).
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 1195-1205
-
-
Eyre, D.W.1
-
50
-
-
84960097403
-
Genome-based infection tracking reveals dynamics of Clostridium difficile transmission and disease recurrence
-
Kumar, N. et al. Genome-based infection tracking reveals dynamics of Clostridium difficile transmission and disease recurrence. Clin. Infect. Dis. 62, 746-752 (2016).
-
(2016)
Clin. Infect. Dis.
, vol.62
, pp. 746-752
-
-
Kumar, N.1
-
51
-
-
85027861396
-
Comparison of control of Clostridium difficile infection in six english hospitals using whole-genome sequencing
-
Eyre, D. W. et al. Comparison of control of Clostridium difficile infection in six english hospitals using whole-genome sequencing. Clin. Infect. Dis. 65, 433-441 (2017).
-
(2017)
Clin. Infect. Dis.
, vol.65
, pp. 433-441
-
-
Eyre, D.W.1
-
52
-
-
85014653259
-
A review of experimental and off-label therapies for Clostridium difficile infection
-
Feher, C., Soriano, A. & Mensa, J. A review of experimental and off-label therapies for Clostridium difficile infection. Infect. Dis. Ther. 6, 1-35 (2017).
-
(2017)
Infect. Dis. Ther.
, vol.6
, pp. 1-35
-
-
Feher, C.1
Soriano, A.2
Mensa, J.3
-
53
-
-
84941615946
-
Cadazolid: A new hope in the treatment of Clostridium difficile infection
-
Kali, A., Charles, M. V. & Srirangaraj, S. Cadazolid: a new hope in the treatment of Clostridium difficile infection. Australas. Med. J. 8, 253-262 (2015).
-
(2015)
Australas. Med. J.
, vol.8
, pp. 253-262
-
-
Kali, A.1
Charles, M.V.2
Srirangaraj, S.3
-
54
-
-
84893466318
-
In vitro and in vivo antibacterial evaluation of cadazolid, a new antibiotic for treatment of Clostridium difficile infections
-
Locher, H. H. et al. In vitro and in vivo antibacterial evaluation of cadazolid, a new antibiotic for treatment of Clostridium difficile infections. Antimicrob. Agents Chemother. 58, 892-900 (2014).
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 892-900
-
-
Locher, H.H.1
-
55
-
-
84894042563
-
In vitro activity of cadazolid against clinically relevant Clostridium difficile isolates and in an in vitro gut model of C. Difficile infection
-
Chilton, C. H. et al. In vitro activity of cadazolid against clinically relevant Clostridium difficile isolates and in an in vitro gut model of C. difficile infection. J. Antimicrob. Chemother. 69, 697-705 (2014).
-
(2014)
J. Antimicrob. Chemother.
, vol.69
, pp. 697-705
-
-
Chilton, C.H.1
-
56
-
-
84960097300
-
Susceptibility of Clostridium difficile isolates from a Phase 2 clinical trial of cadazolid and vancomycin in C. Difficile infection
-
Gerding, D. N. et al. Susceptibility of Clostridium difficile isolates from a Phase 2 clinical trial of cadazolid and vancomycin in C. difficile infection. J. Antimicrob. Chemother. 71, 213-219 (2016).
-
(2016)
J. Antimicrob. Chemother.
, vol.71
, pp. 213-219
-
-
Gerding, D.N.1
-
57
-
-
84958125272
-
Discovery and development of surotomycin for the treatment of Clostridium difficile
-
Knight-Connoni, V., Mascio, C., Chesnel, L. & Silverman, J. Discovery and development of surotomycin for the treatment of Clostridium difficile. J. Ind. Microbiol. Biotechnol. 43, 195-204 (2016).
-
(2016)
J. Ind. Microbiol. Biotechnol.
, vol.43
, pp. 195-204
-
-
Knight-Connoni, V.1
Mascio, C.2
Chesnel, L.3
Silverman, J.4
-
58
-
-
84905977547
-
Efficacy of surotomycin in an in vitro gut model of Clostridium difficile infection
-
Chilton, C. H. et al. Efficacy of surotomycin in an in vitro gut model of Clostridium difficile infection. J. Antimicrob. Chemother. 69, 2426-2433 (2014).
-
(2014)
J. Antimicrob. Chemother.
, vol.69
, pp. 2426-2433
-
-
Chilton, C.H.1
-
59
-
-
84994691299
-
Surotomycin versus vancomycin for Clostridium difficile infection: Phase 2, randomized, controlled, double-blind, non-inferiority, multicentre trial
-
Lee, C. H. et al. Surotomycin versus vancomycin for Clostridium difficile infection: phase 2, randomized, controlled, double-blind, non-inferiority, multicentre trial. J. Antimicrob. Chemother. 71, 2964-2971 (2016).
-
(2016)
J. Antimicrob. Chemother.
, vol.71
, pp. 2964-2971
-
-
Lee, C.H.1
-
60
-
-
85014224252
-
Primary outcomes from a phase 3, randomized, double-blind, active-controlled trial of surotomycin in subjects with Clostridium difficile infection
-
Boix, V. et al. Primary outcomes from a phase 3, randomized, double-blind, active-controlled trial of surotomycin in subjects with Clostridium difficile infection. Open Forum Infect. Dis. 4, ofw275 (2017).
-
(2017)
Open Forum Infect. Dis.
, vol.4
, pp. ofw275
-
-
Boix, V.1
-
61
-
-
84864386108
-
Mechanism of action of and mechanism of reduced susceptibility to the novel anti-Clostridium difficile compound LFF571
-
Leeds, J. A., Sachdeva, M., Mullin, S., Dzink-Fox, J. & Lamarche, M. J. Mechanism of action of and mechanism of reduced susceptibility to the novel anti-Clostridium difficile compound LFF571. Antimicrob. Agents Chemother. 56, 4463-4465 (2012).
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 4463-4465
-
-
Leeds, J.A.1
Sachdeva, M.2
Mullin, S.3
Dzink-Fox, J.4
Lamarche, M.J.5
-
62
-
-
84921755570
-
Subinhibitory concentrations of LFF571 reduce toxin production by Clostridium difficile
-
Sachdeva, M. & Leeds, J. A. Subinhibitory concentrations of LFF571 reduce toxin production by Clostridium difficile. Antimicrob. Agents Chemother. 59, 1252-1257 (2015).
-
(2015)
Antimicrob. Agents Chemother.
, vol.59
, pp. 1252-1257
-
-
Sachdeva, M.1
Leeds, J.A.2
-
63
-
-
84860186057
-
Comparative in vitro activities of LFF571 against Clostridium difficile and 630 other intestinal strains of aerobic and anaerobic bacteria
-
Citron, D. M., Tyrrell, K. L., Merriam, C. V. & Goldstein, E. J. Comparative in vitro activities of LFF571 against Clostridium difficile and 630 other intestinal strains of aerobic and anaerobic bacteria. Antimicrob. Agents Chemother. 56, 2493-2503 (2012).
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 2493-2503
-
-
Citron, D.M.1
Tyrrell, K.L.2
Merriam, C.V.3
Goldstein, E.J.4
-
64
-
-
84864386615
-
Efficacy of LFF571 in a hamster model of Clostridium difficile infection
-
Trzasko, A., Leeds, J. A., Praestgaard, J., Lamarche, M. J. & McKenney, D. Efficacy of LFF571 in a hamster model of Clostridium difficile infection. Antimicrob. Agents Chemother. 56, 4459-4462 (2012).
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 4459-4462
-
-
Trzasko, A.1
Leeds, J.A.2
Praestgaard, J.3
Lamarche, M.J.4
McKenney, D.5
-
65
-
-
84868024327
-
A first-in-human, randomized, double-blind, placebo-controlled, single-and multiple-ascending oral dose study to assess the safety and tolerability of LFF571 in healthy volunteers
-
Ting, L. S. et al. A first-in-human, randomized, double-blind, placebo-controlled, single-and multiple-ascending oral dose study to assess the safety and tolerability of LFF571 in healthy volunteers. Antimicrob. Agents Chemother. 56, 5946-5951 (2012).
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 5946-5951
-
-
Ting, L.S.1
-
66
-
-
84923252565
-
Multicenter, randomized clinical trial to compare the safety and efficacy of LFF571 and vancomycin for Clostridium difficile infections
-
Mullane, K. et al. Multicenter, randomized clinical trial to compare the safety and efficacy of LFF571 and vancomycin for Clostridium difficile infections. Antimicrob. Agents Chemother. 59, 1435-1440 (2015).
-
(2015)
Antimicrob. Agents Chemother.
, vol.59
, pp. 1435-1440
-
-
Mullane, K.1
-
67
-
-
84965067421
-
Impact on toxin production and cell morphology in Clostridium difficile by ridinilazole (SMT19969), a novel treatment for C. Difficile infection
-
Basseres, E. et al. Impact on toxin production and cell morphology in Clostridium difficile by ridinilazole (SMT19969), a novel treatment for C. difficile infection. J. Antimicrob. Chemother. 71, 1245-1251 (2016).
-
(2016)
J. Antimicrob. Chemother.
, vol.71
, pp. 1245-1251
-
-
Basseres, E.1
-
68
-
-
84971629579
-
Ridinilazole: A novel therapy for Clostridium difficile infection
-
Vickers, R. J. et al. Ridinilazole: a novel therapy for Clostridium difficile infection. Int. J. Antimicrob. Agents 48, 137-143 (2016).
-
(2016)
Int. J. Antimicrob. Agents
, vol.48
, pp. 137-143
-
-
Vickers, R.J.1
-
69
-
-
84893483979
-
Comparative in vitro activities of SMT19969, a new antimicrobial agent, against 162 strains from 35 less frequently recovered intestinal Clostridium species: Implications for Clostridium difficile recurrence
-
Goldstein, E. J., Citron, D. M. & Tyrrell, K. L. Comparative in vitro activities of SMT19969, a new antimicrobial agent, against 162 strains from 35 less frequently recovered intestinal Clostridium species: implications for Clostridium difficile recurrence. Antimicrob. Agents Chemother. 58, 1187-1191 (2014).
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 1187-1191
-
-
Goldstein, E.J.1
Citron, D.M.2
Tyrrell, K.L.3
-
70
-
-
85018283722
-
Efficacy and safety of ridinilazole compared with vancomycin for the treatment of Clostridium difficile infection: A phase 2, randomised, double-blind, active-controlled, non-inferiority study
-
Vickers, R. J. et al. Efficacy and safety of ridinilazole compared with vancomycin for the treatment of Clostridium difficile infection: a phase 2, randomised, double-blind, active-controlled, non-inferiority study. Lancet Infect. Dis. 17, 735-744 (2017).
-
(2017)
Lancet Infect. Dis.
, vol.17
, pp. 735-744
-
-
Vickers, R.J.1
-
71
-
-
84943141832
-
Clostridium difficile infection: A brief update on emerging therapies
-
Goldberg, E. J. et al. Clostridium difficile infection: a brief update on emerging therapies. Am. J. Health Syst. Pharm. 72, 1007-1012 (2015).
-
(2015)
Am. J. Health Syst. Pharm.
, vol.72
, pp. 1007-1012
-
-
Goldberg, E.J.1
-
72
-
-
84962367282
-
Clostridium difficile infection: A review of current and emerging therapies
-
Ofosu, A. Clostridium difficile infection: a review of current and emerging therapies. Ann. Gastroenterol. 29, 147-154 (2016).
-
(2016)
Ann. Gastroenterol.
, vol.29
, pp. 147-154
-
-
Ofosu, A.1
-
73
-
-
85018523685
-
Reducing recurrence of C. Difficile infection
-
Dieterle, M. G. & Young, V. B. Reducing recurrence of C. difficile infection. Cell 169, 375 (2017).
-
(2017)
Cell
, vol.169
, pp. 375
-
-
Dieterle, M.G.1
Young, V.B.2
-
74
-
-
85010953522
-
Bezlotoxumab-A new agent for Clostridium difficile infection
-
Bartlett, J. G. Bezlotoxumab-a new agent for Clostridium difficile infection. N. Engl. J. Med. 376, 381-382 (2017).
-
(2017)
N. Engl. J. Med.
, vol.376
, pp. 381-382
-
-
Bartlett, J.G.1
-
75
-
-
84976315674
-
Bezlotoxumab alone and with actoxumab for prevention of recurrent Clostridium difficile infection in patients on standard of care antibiotics: Integrated results of 2 phase 3 studies (MODIFY I and MODIFY II)
-
Wilcox, M. et al. Bezlotoxumab alone and with actoxumab for prevention of recurrent Clostridium difficile infection in patients on standard of care antibiotics: integrated results of 2 phase 3 studies (MODIFY I and MODIFY II). Open Forum Infect. Dis. 2, 67 (2015).
-
(2015)
Open Forum Infect. Dis.
, vol.2
, pp. 67
-
-
Wilcox, M.1
-
76
-
-
84997294485
-
The monoclonal antitoxin antibodies (actoxumab-be-zlotoxumab) treatment facilitates normalization of the gut microbiota of mice with Clostridium difficile infection
-
Dzunkova, M. et al. The monoclonal antitoxin antibodies (actoxumab-be-zlotoxumab) treatment facilitates normalization of the gut microbiota of mice with Clostridium difficile infection. Front. Cell. Infect. Microbiol. 6, 119 (2016).
-
(2016)
Front. Cell. Infect. Microbiol.
, vol.6
, pp. 119
-
-
Dzunkova, M.1
-
77
-
-
84922032670
-
The potential for emerging therapeutic options for Clostridium difficile infection
-
Mathur, H., Rea, M. C., Cotter, P. D., Ross, R. P. & Hill, C. The potential for emerging therapeutic options for Clostridium difficile infection. Gut Microbes 5, 696-710 (2014).
-
(2014)
Gut Microbes
, vol.5
, pp. 696-710
-
-
Mathur, H.1
Rea, M.C.2
Cotter, P.D.3
Ross, R.P.4
Hill, C.5
-
78
-
-
84996550864
-
Clostridium difficile infection and fecal microbiota transplant
-
Liubakka, A. & Vaughn, B. P. Clostridium difficile infection and fecal microbiota transplant. AACN Adv. Crit. Care 27, 324-337 (2016).
-
(2016)
AACN Adv. Crit. Care
, vol.27
, pp. 324-337
-
-
Liubakka, A.1
Vaughn, B.P.2
-
79
-
-
84875952542
-
Fecal microbiota transplantation for Clostridium difficileinfection: Systematic review and meta-analysis
-
Kassam, Z., Lee, C. H., Yuan, Y. & Hunt, R. H. Fecal microbiota transplantation for Clostridium difficileinfection: systematic review and meta-analysis. Am. J. Gastroenterol. 108, 500-508 (2013).
-
(2013)
Am. J. Gastroenterol.
, vol.108
, pp. 500-508
-
-
Kassam, Z.1
Lee, C.H.2
Yuan, Y.3
Hunt, R.H.4
-
80
-
-
84908681868
-
Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridium difficile infection
-
Youngster, I. et al. Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridium difficile infection. JAMA 312, 1772-1778 (2014).
-
(2014)
JAMA
, vol.312
, pp. 1772-1778
-
-
Youngster, I.1
-
81
-
-
84994514545
-
A retrospective comparison of fecal microbial transplantation methods for recurrent Clostridium difficile infection
-
Cohen, N. A. et al. A retrospective comparison of fecal microbial transplantation methods for recurrent Clostridium difficile infection. Isr. Med. Assoc. J. 18, 594-599 (2016).
-
(2016)
Isr. Med. Assoc. J.
, vol.18
, pp. 594-599
-
-
Cohen, N.A.1
-
82
-
-
84960130524
-
Safety and durability of RBX2660 (microbiota suspension) for recurrent Clostridium difficile infection: Results of the PUNCH CD study
-
Orenstein, R. et al. Safety and durability of RBX2660 (microbiota suspension) for recurrent Clostridium difficile infection: results of the PUNCH CD study. Clin. Infect. Dis. 62, 596-602 (2016).
-
(2016)
Clin. Infect. Dis.
, vol.62
, pp. 596-602
-
-
Orenstein, R.1
-
83
-
-
84991447029
-
New and emerging therapies for Clostridium difficile infection
-
Martin, J. & Wilcox, M. New and emerging therapies for Clostridium difficile infection. Curr. Opin. Infect. Dis. 29, 546-554 (2016).
-
(2016)
Curr. Opin. Infect. Dis.
, vol.29
, pp. 546-554
-
-
Martin, J.1
Wilcox, M.2
-
84
-
-
77954424086
-
Dose-response efficacy of a proprietary probiotic formula of Lactobacillus acidophilus CL1285 and Lactobacillus caseiLBC80R for antibiotic-associated diarrhea and Clostridium difficile-associated diarrhea prophylaxis in adult patients
-
Gao, X. W., Mubasher, M., Fang, C. Y., Reifer, C. & Miller, L. E. Dose-response efficacy of a proprietary probiotic formula of Lactobacillus acidophilus CL1285 and Lactobacillus caseiLBC80R for antibiotic-associated diarrhea and Clostridium difficile-associated diarrhea prophylaxis in adult patients. Am. J. Gastroenterol. 105, 1636-1641 (2010).
-
(2010)
Am. J. Gastroenterol.
, vol.105
, pp. 1636-1641
-
-
Gao, X.W.1
Mubasher, M.2
Fang, C.Y.3
Reifer, C.4
Miller, L.E.5
-
85
-
-
84928891429
-
A decade of experience in primary prevention of Clostridium difficileinfection at a community hospital using the probiotic combination Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R, and Lactobacillus rhamnosus CLR2 (Bio-K+)
-
Maziade, P. J., Pereira, P. & Goldstein, E. J. A decade of experience in primary prevention of Clostridium difficileinfection at a community hospital using the probiotic combination Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R, and Lactobacillus rhamnosus CLR2 (Bio-K+). Clin. Infect. Dis. 60(Suppl. 2), S144-S147 (2015).
-
(2015)
Clin. Infect. Dis.
, vol.60
, pp. S144-S147
-
-
Maziade, P.J.1
Pereira, P.2
Goldstein, E.J.3
-
86
-
-
84891816574
-
Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children
-
Goldenberg, J. Z. et al. Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database Syst. Rev. Cd006095, https://doi.org/10.1002/14651858.CD006095.pub3 (2013).
-
(2013)
Cochrane Database Syst. Rev.
, pp. Cd006095
-
-
Goldenberg, J.Z.1
-
87
-
-
84871349683
-
Probiotics for the prevention of Clostridium difficile-associated diarrhea: A systematic review and meta-analysis
-
Johnston, B. C. et al. Probiotics for the prevention of Clostridium difficile-associated diarrhea: a systematic review and meta-analysis. Ann. Intern. Med. 157, 878-888 (2012).
-
(2012)
Ann. Intern. Med.
, vol.157
, pp. 878-888
-
-
Johnston, B.C.1
-
88
-
-
85019055660
-
A combination of the probiotic and prebiotic product can prevent the germination of Clostridium difficile spores and infection
-
Ratsep, M. et al. A combination of the probiotic and prebiotic product can prevent the germination of Clostridium difficile spores and infection. Anaerobe 47, 94-103 (2017).
-
(2017)
Anaerobe
, vol.47
, pp. 94-103
-
-
Ratsep, M.1
-
89
-
-
84861908072
-
Saccharomyces boulardii for the prevention of antibiotic-associated diarrhea in adult hospitalized patients: A single-center, randomized, double-blind, placebo-controlled trial
-
Pozzoni, P. et al. Saccharomyces boulardii for the prevention of antibiotic-associated diarrhea in adult hospitalized patients: a single-center, randomized, double-blind, placebo-controlled trial. Am. J. Gastroenterol. 107, 922-931 (2012).
-
(2012)
Am. J. Gastroenterol.
, vol.107
, pp. 922-931
-
-
Pozzoni, P.1
-
90
-
-
0042922857
-
Lactobacillus plantarum 299v for the treatment of recurrent Clostridium difficile-associated diarrhoea: A double-blind, placebo-controlled trial
-
Wullt, M., Hagslatt, M. L. & Odenholt, I. Lactobacillus plantarum 299v for the treatment of recurrent Clostridium difficile-associated diarrhoea: a double-blind, placebo-controlled trial. Scand. J. Infect. Dis. 35, 365-367 (2003).
-
(2003)
Scand. J. Infect. Dis.
, vol.35
, pp. 365-367
-
-
Wullt, M.1
Hagslatt, M.L.2
Odenholt, I.3
-
91
-
-
0033985298
-
The effect of probiotics on Clostridium difficile diarrhea
-
Pochapin, M. The effect of probiotics on Clostridium difficile diarrhea. Am. J. Gastroenterol. 95, S11-S13 (2000).
-
(2000)
Am. J. Gastroenterol.
, vol.95
, pp. S11-S13
-
-
Pochapin, M.1
-
92
-
-
84889608780
-
A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: A multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (PLACIDE)
-
Allen, S. J. et al. A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: a multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (PLACIDE). Health Technol. Assess. 17, 1-140 (2013).
-
(2013)
Health Technol. Assess.
, vol.17
, pp. 1-140
-
-
Allen, S.J.1
-
93
-
-
84887390865
-
Lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea and Clostridium difficile diarrhoea in older inpatients (PLACIDE): A randomised, double-blind, placebo-controlled, multicentre trial
-
Allen, S. J. et al. Lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea and Clostridium difficile diarrhoea in older inpatients (PLACIDE): a randomised, double-blind, placebo-controlled, multicentre trial. Lancet 382, 1249-1257 (2013).
-
(2013)
Lancet
, vol.382
, pp. 1249-1257
-
-
Allen, S.J.1
-
94
-
-
84866313203
-
Evaluation of an oral suspension of VP20621, spores of nontoxigenic Clostridium difficile strain M3, in healthy subjects
-
Villano, S. A., Seiberling, M., Tatarowicz, W., Monnot-Chase, E. & Gerding, D. N. Evaluation of an oral suspension of VP20621, spores of nontoxigenic Clostridium difficile strain M3, in healthy subjects. Antimicrob. Agents Chemother. 56, 5224-5229 (2012).
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 5224-5229
-
-
Villano, S.A.1
Seiberling, M.2
Tatarowicz, W.3
Monnot-Chase, E.4
Gerding, D.N.5
-
95
-
-
84885915939
-
Nontoxigenic Clostridium difficile protects hamsters against challenge with historic and epidemic strains of toxigenic BI/NAP1/027 C. Difficile
-
Nagaro, K. J. et al. Nontoxigenic Clostridium difficile protects hamsters against challenge with historic and epidemic strains of toxigenic BI/NAP1/027 C. difficile. Antimicrob. Agents Chemother. 57, 5266-5270 (2013).
-
(2013)
Antimicrob. Agents Chemother.
, vol.57
, pp. 5266-5270
-
-
Nagaro, K.J.1
-
96
-
-
84945302337
-
The non-toxigenic Clostridium difficileCD37 protects mice against infection with a BI/NAP1/027 type of C. Difficile strain
-
Zhang, K. et al. The non-toxigenic Clostridium difficileCD37 protects mice against infection with a BI/NAP1/027 type of C. difficile strain. Anaerobe 36, 49-52 (2015).
-
(2015)
Anaerobe
, vol.36
, pp. 49-52
-
-
Zhang, K.1
-
97
-
-
84929148131
-
Administration of spores of nontoxigenic Clostridium difficile strain M3 for prevention of recurrent C. Difficile infection: A randomized clinical trial
-
Gerding, D. N. et al. Administration of spores of nontoxigenic Clostridium difficile strain M3 for prevention of recurrent C. difficile infection: a randomized clinical trial. JAMA 313, 1719-1727 (2015).
-
(2015)
JAMA
, vol.313
, pp. 1719-1727
-
-
Gerding, D.N.1
-
98
-
-
84939574142
-
Investigational new treatments for Clostridium difficile infection
-
Ivarsson, M. E., Leroux, J. C. & Castagner, B. Investigational new treatments for Clostridium difficile infection. Drug Discov. Today 20, 602-608 (2015).
-
(2015)
Drug Discov. Today
, vol.20
, pp. 602-608
-
-
Ivarsson, M.E.1
Leroux, J.C.2
Castagner, B.3
-
99
-
-
84954569031
-
Using a novel lysin to help control Clostridium difficile infections
-
Wang, Q., Euler, C. W., Delaune, A. & Fischetti, V. A. Using a novel lysin to help control Clostridium difficile infections. Antimicrob. Agents Chemother. 59, 7447-7457 (2015).
-
(2015)
Antimicrob. Agents Chemother.
, vol.59
, pp. 7447-7457
-
-
Wang, Q.1
Euler, C.W.2
Delaune, A.3
Fischetti, V.A.4
-
100
-
-
44649117522
-
Human alpha-defensins inhibit Clostridium difficile toxin B
-
Giesemann, T., Guttenberg, G. & Aktories, K. Human alpha-defensins inhibit Clostridium difficile toxin B. Gastroenterology 134, 2049-2058 (2008).
-
(2008)
Gastroenterology
, vol.134
, pp. 2049-2058
-
-
Giesemann, T.1
Guttenberg, G.2
Aktories, K.3
-
101
-
-
84923039622
-
New role for human alpha-defensin 5 in the fight against hypervirulent Clostridium difficile strains
-
Furci, L. et al New role for human alpha-defensin 5 in the fight against hypervirulent Clostridium difficile strains. Infect. Immun. 83, 986-995 (2015).
-
(2015)
Infect. Immun.
, vol.83
, pp. 986-995
-
-
Furci, L.1
-
102
-
-
84942543705
-
A small-molecule antivirulence agent for treating Clostridium difficile infection
-
Bender, K. O. et al. A small-molecule antivirulence agent for treating Clostridium difficile infection. Sci. Transl. Med. 7, 306ra148 (2015).
-
(2015)
Sci. Transl. Med.
, vol.7
, pp. 306ra148
-
-
Bender, K.O.1
-
103
-
-
84905057299
-
Vancomycin, metronidazole, or tolevamer for Clostridium difficile infection: Results from two multinational, randomized, controlled trials
-
Johnson, S. et al. Vancomycin, metronidazole, or tolevamer for Clostridium difficile infection: results from two multinational, randomized, controlled trials. Clin. Infect. Dis. 59, 345-354 (2014).
-
(2014)
Clin. Infect. Dis.
, vol.59
, pp. 345-354
-
-
Johnson, S.1
-
104
-
-
84988603121
-
Clostridium difficilein food and animals: A comprehensive review
-
Rodriguez, C., Taminiau, B., Van Broeck, J., Delmee, M. & Daube, G. Clostridium difficilein food and animals: a comprehensive review. Adv. Exp. Med. Biol. 932, 65-92 (2016).
-
(2016)
Adv. Exp. Med. Biol.
, vol.932
, pp. 65-92
-
-
Rodriguez, C.1
Taminiau, B.2
Van Broeck, J.3
Delmee, M.4
Daube, G.5
-
105
-
-
40749128497
-
Clostridium difficile PCR ribotype 078: An emerging strain in humans and in pigs?
-
Goorhuis, A. et al Clostridium difficile PCR ribotype 078: an emerging strain in humans and in pigs? J. Clin. Microbiol. 46, 1157 (2008).
-
(2008)
J. Clin. Microbiol.
, vol.46
, pp. 1157
-
-
Goorhuis, A.1
-
106
-
-
84902899123
-
International Clostridium difficile animal strain collection and large diversity of animal associated strains
-
Janezic, S. et al. International Clostridium difficile animal strain collection and large diversity of animal associated strains. BMC Microbiol. 14, 173 (2014).
-
(2014)
BMC Microbiol.
, vol.14
, pp. 173
-
-
Janezic, S.1
-
108
-
-
84922909621
-
Whole genome sequencing reveals potential spread of Clostridium difficile between humans and farm animals in the Netherlands 2002 to 2011
-
Knetsch, C. W. et al. Whole genome sequencing reveals potential spread of Clostridium difficile between humans and farm animals in the Netherlands, 2002 to 2011. Eur. Surveill. 19, 20954 (2014).
-
(2014)
Eur. Surveill.
, vol.19
, pp. 20954
-
-
Knetsch, C.W.1
-
109
-
-
85041955736
-
Human Clostridium difficile infection caused by a livestock-associated PCR ribotype 237 strain in Western Austrialia
-
Mc Govern, A. M. et al. Human Clostridium difficile infection caused by a livestock-associated PCR ribotype 237 strain in Western Austrialia. JMM Case Rep. 3, e005062 (2016).
-
(2016)
JMM Case Rep.
, vol.3
, pp. e005062
-
-
Mc Govern, A.M.1
|