Genome-Based Infection Tracking Reveals Dynamics of Clostridium difficile Transmission and Disease Recurrence

Clinical Infectious Diseases

Volumn 62, Issue 6, 2015, Pages 746-752

  Kumar, Nitin ^a   Miyajima, Fabio ^b   He, Miao ^a   Roberts, Paul ^c   Swale, Andrew ^b   Ellison, Louise ^a   Pickard, Derek ^a   Smith, Godfrey ^c   Molyneux, Rebecca ^c   Dougan, Gordon ^a   Parkhill, Julian ^a   Wren, Brendan W ^d   Parry, Christopher M ^d   Pirmohamed, Munir ^b   Lawley, Trevor D ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

C. difficile 027 ST1; Highly contagious individuals; Recurrence; Ward based transmission; Whole genome sequencing

Indexed keywords

ADULT; ARTICLE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; BACTERIUM ISOLATE; CLOSTRIDIUM DIFFICILE INFECTION; DIARRHEA; EPIDEMIC; GENE SEQUENCE; GENOTYPE; HEALTH CARE FACILITY; HOSPITAL PATIENT; HUMAN; INCIDENCE; INFECTION CONTROL; MAJOR CLINICAL STUDY; PATIENT CARE; PEPTOCLOSTRIDIUM DIFFICILE; PHYLOGENY; PRIORITY JOURNAL; RECURRENT INFECTION; REINFECTION; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED KINGDOM; WARD; WHOLE GENOME SEQUENCING; CLOSTRIDIUM INFECTIONS; CROSS INFECTION; DISEASE OUTBREAKS; DNA SEQUENCE; FEMALE; GENETICS; HOSPITALIZATION; ISOLATION AND PURIFICATION; MALE; MICROBIOLOGY; MIDDLE AGED; RECURRENT DISEASE; RIBOTYPING; TRANSMISSION; YOUNG ADULT;

ADULT; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; CROSS INFECTION; DISEASE OUTBREAKS; FEMALE; GENOME, BACTERIAL; GENOTYPE; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; PHYLOGENY; POLYMORPHISM, SINGLE NUCLEOTIDE; RECURRENCE; RIBOTYPING; SEQUENCE ANALYSIS, DNA; UNITED KINGDOM; YOUNG ADULT;

EID: 84960097403     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/civ1031     Document Type: Article

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