-
1
-
-
84863694101
-
Burden of Clostridium difficile on the healthcare system
-
Dubberke ER, Olsen MA. 2012. Burden of Clostridium difficile on the healthcare system. Clin Infect Dis 55(Suppl 2):S88-S92. http://dx.doi.org/10.1093/cid/cis335.
-
(2012)
Clin Infect Dis
, vol.55
, pp. S88-S92
-
-
Dubberke, E.R.1
Olsen, M.A.2
-
2
-
-
78651111353
-
Clostridium difficile infection: epidemiology, risk factors and management
-
Ananthakrishnan AN. 2011. Clostridium difficile infection: epidemiology, risk factors and management. Nat Rev Gastroenterol Hepatol 8:17-26. http://dx.doi.org/10.1038/nrgastro.2010.190.
-
(2011)
Nat Rev Gastroenterol Hepatol
, vol.8
, pp. 17-26
-
-
Ananthakrishnan, A.N.1
-
3
-
-
84878893265
-
Clostridium difficile infection is associated with increased risk of death and prolonged hospitalization in children
-
Sammons JS, Localio R, Xiao R, Coffin SE, Zaoutis T. 2013. Clostridium difficile infection is associated with increased risk of death and prolonged hospitalization in children. Clin Infect Dis 57:1-8. http://dx.doi.org/10.1093/cid/cit155.
-
(2013)
Clin Infect Dis
, vol.57
, pp. 1-8
-
-
Sammons, J.S.1
Localio, R.2
Xiao, R.3
Coffin, S.E.4
Zaoutis, T.5
-
4
-
-
84877306933
-
Relationship between bacterial strain type, host biomarkers, and mortality in Clostridium difficile infection
-
Walker AS, Eyre DW, Wyllie DH, Dingle KE, Griffiths D, Shine B, Oakley S, O'Connor L, Finney J, Vaughan A, Crook DW, Wilcox MH, Peto TE. 2013. Relationship between bacterial strain type, host biomarkers, and mortality in Clostridium difficile infection. Clin Infect Dis 56: 1589-1600. http://dx.doi.org/10.1093/cid/cit127.
-
(2013)
Clin Infect Dis
, vol.56
, pp. 1589-1600
-
-
Walker, A.S.1
Eyre, D.W.2
Wyllie, D.H.3
Dingle, K.E.4
Griffiths, D.5
Shine, B.6
Oakley, S.7
O'Connor, L.8
Finney, J.9
Vaughan, A.10
Crook, D.W.11
Wilcox, M.H.12
Peto, T.E.13
-
5
-
-
78650825355
-
Clostridium difficile infection in Europe: a hospital-based survey
-
Bauer MP, Notermans DW, van Benthem BH, Brazier JS, Wilcox MH, Rupnik M, Monnet DL, van Dissel JT, Kuijper EJ. 2011. Clostridium difficile infection in Europe: a hospital-based survey. Lancet 377:63-73. http://dx.doi.org/10.1016/S0140-6736(10)61266-4.
-
(2011)
Lancet
, vol.377
, pp. 63-73
-
-
Bauer, M.P.1
Notermans, D.W.2
van Benthem, B.H.3
Brazier, J.S.4
Wilcox, M.H.5
Rupnik, M.6
Monnet, D.L.7
van Dissel, J.T.8
Kuijper, E.J.9
-
6
-
-
77955433596
-
Clostridium difficile isolates resistant to fluoroquinolones in Italy: emergence of PCR ribotype 018
-
Spigaglia P, Barbanti F, Dionisi AM, Mastrantonio P. 2010. Clostridium difficile isolates resistant to fluoroquinolones in Italy: emergence of PCR ribotype 018. J Clin Microbiol 48:2892-2896. http://dx.doi.org/10.1128/JCM.02482-09.
-
(2010)
J Clin Microbiol
, vol.48
, pp. 2892-2896
-
-
Spigaglia, P.1
Barbanti, F.2
Dionisi, A.M.3
Mastrantonio, P.4
-
7
-
-
72049099881
-
First report of hypervirulent strains polymerase chain reaction ribotypes 027 and 078 causing severe Clostridium difficile infection in Italy
-
Baldan R, Cavallerio P, Tuscano A, Parlato C, Fossati L, Moro M, Serra R, Cirillo DM. 2010. First report of hypervirulent strains polymerase chain reaction ribotypes 027 and 078 causing severe Clostridium difficile infection in Italy. Clin Infect Dis 50:126-127. http://dx.doi.org/10.1086/649011.
-
(2010)
Clin Infect Dis
, vol.50
, pp. 126-127
-
-
Baldan, R.1
Cavallerio, P.2
Tuscano, A.3
Parlato, C.4
Fossati, L.5
Moro, M.6
Serra, R.7
Cirillo, D.M.8
-
8
-
-
79955548228
-
Comparison of strain typing results for Clostridium difficile isolates from North America
-
Tenover FC, Akerlund T, Gerding DN, Goering RV, Bostrom T, Jonsson AM, Wong E, Wortman AT, Persing DH. 2011. Comparison of strain typing results for Clostridium difficile isolates from North America. J Clin Microbiol 49:1831-1837. http://dx.doi.org/10.1128/JCM.02446-10.
-
(2011)
J Clin Microbiol
, vol.49
, pp. 1831-1837
-
-
Tenover, F.C.1
Akerlund, T.2
Gerding, D.N.3
Goering, R.V.4
Bostrom, T.5
Jonsson, A.M.6
Wong, E.7
Wortman, A.T.8
Persing, D.H.9
-
9
-
-
79959756757
-
Clostridium difficile infection: a comprehensive review
-
Kachrimanidou M, Malisiovas N. 2011. Clostridium difficile infection: a comprehensive review. Crit Rev Microbiol 37:178-187. http://dx.doi.org/10.3109/1040841X.2011.556598.
-
(2011)
Crit Rev Microbiol
, vol.37
, pp. 178-187
-
-
Kachrimanidou, M.1
Malisiovas, N.2
-
10
-
-
39349107697
-
Decreased diversity of the fecal microbiome in recurrent Clostridium difficile-associated diarrhea
-
Chang JY, Antonopoulos DA, Kalra A, Tonelli A, Khalife WT, Schmidt TM, Young VB. 2008. Decreased diversity of the fecal microbiome in recurrent Clostridium difficile-associated diarrhea. J Infect Dis 197:435-438. http://dx.doi.org/10.1086/525047.
-
(2008)
J Infect Dis
, vol.197
, pp. 435-438
-
-
Chang, J.Y.1
Antonopoulos, D.A.2
Kalra, A.3
Tonelli, A.4
Khalife, W.T.5
Schmidt, T.M.6
Young, V.B.7
-
11
-
-
84868203487
-
Immune responses to Clostridium difficile infection
-
Madan R, Petri WA, Jr. 2012. Immune responses to Clostridium difficile infection. Trends Mol Med 18:658-666. http://dx.doi.org/10.1016/j.molmed.2012.09.005.
-
(2012)
Trends Mol Med
, vol.18
, pp. 658-666
-
-
Madan, R.1
Petri, W.A.2
-
13
-
-
83655193502
-
α-Defensins in human innate immunity
-
Lehrer RI, Lu W. 2012. α-Defensins in human innate immunity. Immunol Rev 245:84-112. http://dx.doi.org/10.1111/j.1600-065X.2011.01082.x.
-
(2012)
Immunol Rev
, vol.245
, pp. 84-112
-
-
Lehrer, R.I.1
Lu, W.2
-
14
-
-
79551686484
-
Microbiota-immune system interaction: an uneasy alliance
-
Salzman NH. 2011. Microbiota-immune system interaction: an uneasy alliance. Curr Opin Microbiol 14:99-105. http://dx.doi.org/10.1016/j.mib.2010.09.018.
-
(2011)
Curr Opin Microbiol
, vol.14
, pp. 99-105
-
-
Salzman, N.H.1
-
15
-
-
0036079594
-
Paneth cell trypsin is the processing enzyme for human defensin-5
-
Ghosh D, Porter E, Shen B, Lee SK, Wilk D, Drazba J, Yadav SP, Crabb JW, Ganz T, Bevins CL. 2002. Paneth cell trypsin is the processing enzyme for human defensin-5. Nat Immunol 3:583-590. http://dx.doi.org/10.1038/ni797.
-
(2002)
Nat Immunol
, vol.3
, pp. 583-590
-
-
Ghosh, D.1
Porter, E.2
Shen, B.3
Lee, S.K.4
Wilk, D.5
Drazba, J.6
Yadav, S.P.7
Crabb, J.W.8
Ganz, T.9
Bevins, C.L.10
-
16
-
-
33947579340
-
Alpha-defensins block the early steps of HIV-1 infection: interference with the binding of gp120 to CD4
-
Furci L, Sironi F, Tolazzi M, Vassena L, Lusso P. 2007. Alpha-defensins block the early steps of HIV-1 infection: interference with the binding of gp120 to CD4. Blood 109:2928-2935. http://dx.doi.org/10.1182/blood-2006-05-024489.
-
(2007)
Blood
, vol.109
, pp. 2928-2935
-
-
Furci, L.1
Sironi, F.2
Tolazzi, M.3
Vassena, L.4
Lusso, P.5
-
17
-
-
2542480000
-
Multiple roles of antimicrobial defensins, cathelicidins, and eosinophilderived neurotoxin in host defense
-
Yang D, Biragyn A, Hoover DM, Lubkowski J, Oppenheim JJ. 2004. Multiple roles of antimicrobial defensins, cathelicidins, and eosinophilderived neurotoxin in host defense. Annu Rev Immunol 22:181-215. http://dx.doi.org/10.1146/annurev.immunol.22.012703.104603.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 181-215
-
-
Yang, D.1
Biragyn, A.2
Hoover, D.M.3
Lubkowski, J.4
Oppenheim, J.J.5
-
18
-
-
33751545243
-
Crystal structures of human alpha-defensins HNP4, HD5, and HD6
-
Szyk A, Wu Z, Tucker K, Yang D, Lu W, Lubkowski J. 2006. Crystal structures of human alpha-defensins HNP4, HD5, and HD6. Protein Sci 15:2749-2760. http://dx.doi.org/10.1110/ps.062336606.
-
(2006)
Protein Sci
, vol.15
, pp. 2749-2760
-
-
Szyk, A.1
Wu, Z.2
Tucker, K.3
Yang, D.4
Lu, W.5
Lubkowski, J.6
-
19
-
-
74049122536
-
Enteric defensins are essential regulators of intestinal microbial ecology
-
Salzman NH, Hung K, Haribhai D, Chu H, Karlsson-Sjoberg J, Amir E, Teggatz P, Barman M, Hayward M, Eastwood D, Stoel M, Zhou Y, Sodergren E, Weinstock GM, Bevins CL, Williams CB, Bos NA. 2010. Enteric defensins are essential regulators of intestinal microbial ecology. Nat Immunol 11:76-83. http://dx.doi.org/10.1038/ni.1825.
-
(2010)
Nat Immunol
, vol.11
, pp. 76-83
-
-
Salzman, N.H.1
Hung, K.2
Haribhai, D.3
Chu, H.4
Karlsson-Sjoberg, J.5
Amir, E.6
Teggatz, P.7
Barman, M.8
Hayward, M.9
Eastwood, D.10
Stoel, M.11
Zhou, Y.12
Sodergren, E.13
Weinstock, G.M.14
Bevins, C.L.15
Williams, C.B.16
Bos, N.A.17
-
20
-
-
84863582194
-
Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of alpha-defensins
-
Eriguchi Y, Takashima S, Oka H, Shimoji S, Nakamura K, Uryu H, Shimoda S, Iwasaki H, Shimono N, Ayabe T, Akashi K, Teshima T. 2012. Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of alpha-defensins. Blood 120:223-231. http://dx.doi.org/10.1182/blood-2011-12-401166.
-
(2012)
Blood
, vol.120
, pp. 223-231
-
-
Eriguchi, Y.1
Takashima, S.2
Oka, H.3
Shimoji, S.4
Nakamura, K.5
Uryu, H.6
Shimoda, S.7
Iwasaki, H.8
Shimono, N.9
Ayabe, T.10
Akashi, K.11
Teshima, T.12
-
21
-
-
79954915318
-
Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis
-
Bevins CL, Salzman NH. 2011. Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis. Nat Rev Microbiol 9:356-368. http://dx.doi.org/10.1038/nrmicro2546.
-
(2011)
Nat Rev Microbiol
, vol.9
, pp. 356-368
-
-
Bevins, C.L.1
Salzman, N.H.2
-
22
-
-
58549111588
-
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
-
Vaishnava S, Behrendt CL, Ismail AS, Eckmann L, Hooper LV. 2008. Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci USA 105: 20858-20863. http://dx.doi.org/10.1073/pnas.0808723105.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20858-20863
-
-
Vaishnava, S.1
Behrendt, C.L.2
Ismail, A.S.3
Eckmann, L.4
Hooper, L.V.5
-
23
-
-
84872275787
-
Bacterial stimulation of the TLRMyD88 pathway modulates the homeostatic expression of ileal Paneth cell alpha-defensins
-
Menendez A, Willing BP, Montero M, Wlodarska M, So CC, Bhinder G, Vallance BA, Finlay BB. 2013. Bacterial stimulation of the TLRMyD88 pathway modulates the homeostatic expression of ileal Paneth cell alpha-defensins. J Innate Immun 5:39-49. http://dx.doi.org/10.1159/000341630.
-
(2013)
J Innate Immun
, vol.5
, pp. 39-49
-
-
Menendez, A.1
Willing, B.P.2
Montero, M.3
Wlodarska, M.4
So, C.C.5
Bhinder, G.6
Vallance, B.A.7
Finlay, B.B.8
-
24
-
-
29144483937
-
Reduced Paneth cell alpha-defensins in ileal Crohn's disease
-
Wehkamp J, Salzman NH, Porter E, Nuding S, Weichenthal M, Petras RE, Shen B, Schaeffeler E, Schwab M, Linzmeier R, Feathers RW, Chu H, Lima H, Jr, Fellermann K, Ganz T, Stange EF, Bevins CL. 2005. Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proc Natl Acad Sci USA 102:18129-18134. http://dx.doi.org/10.1073/pnas.0505256102.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18129-18134
-
-
Wehkamp, J.1
Salzman, N.H.2
Porter, E.3
Nuding, S.4
Weichenthal, M.5
Petras, R.E.6
Shen, B.7
Schaeffeler, E.8
Schwab, M.9
Linzmeier, R.10
Feathers, R.W.11
Chu, H.12
Lima, H.13
Fellermann, K.14
Ganz, T.15
Stange, E.F.16
Bevins, C.L.17
-
25
-
-
0037417311
-
Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin
-
Salzman NH, Ghosh D, Huttner KM, Paterson Y, Bevins CL. 2003. Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin. Nature 422:522-526. http://dx.doi.org/10.1038/nature01520.
-
(2003)
Nature
, vol.422
, pp. 522-526
-
-
Salzman, N.H.1
Ghosh, D.2
Huttner, K.M.3
Paterson, Y.4
Bevins, C.L.5
-
26
-
-
0021848749
-
Clostridium difficile in patients with cystic fibrosis
-
Welkon CJ, Long SS, Thompson CM, Jr, Gilligan PH. 1985. Clostridium difficile in patients with cystic fibrosis. Am J Dis Child 139:805-808.
-
(1985)
Am J Dis Child
, vol.139
, pp. 805-808
-
-
Welkon, C.J.1
Long, S.S.2
Thompson, C.M.3
Gilligan, P.H.4
-
27
-
-
44649117522
-
Human alpha-defensins inhibit Clostridium difficile toxin B
-
Giesemann T, Guttenberg G, Aktories K. 2008. Human alpha-defensins inhibit Clostridium difficile toxin B. Gastroenterology 134:2049-2058. http://dx.doi.org/10.1053/j.gastro.2008.03.008.
-
(2008)
Gastroenterology
, vol.134
, pp. 2049-2058
-
-
Giesemann, T.1
Guttenberg, G.2
Aktories, K.3
-
28
-
-
84866460958
-
Clostridium difficile infection: toxins and non-toxin virulence factors, and their contributions to disease establishment and host response
-
Vedantam G, Clark A, Chu M, McQuade R, Mallozzi M, Viswanathan VK. 2012. Clostridium difficile infection: toxins and non-toxin virulence factors, and their contributions to disease establishment and host response. Gut Microbes 3:121-134. http://dx.doi.org/10.4161/gmic.19399.
-
(2012)
Gut Microbes
, vol.3
, pp. 121-134
-
-
Vedantam, G.1
Clark, A.2
Chu, M.3
McQuade, R.4
Mallozzi, M.5
Viswanathan, V.K.6
-
29
-
-
79955048935
-
Nucleotide-binding oligomerization domain 1 mediates recognition of Clostridium difficile and induces neutrophil recruitment and protection against the pathogen
-
Hasegawa M, Yamazaki T, Kamada N, Tawaratsumida K, Kim YG, Nunez G, Inohara N. 2011. Nucleotide-binding oligomerization domain 1 mediates recognition of Clostridium difficile and induces neutrophil recruitment and protection against the pathogen. J Immunol 186:4872-4880. http://dx.doi.org/10.4049/jimmunol.1003761.
-
(2011)
J Immunol
, vol.186
, pp. 4872-4880
-
-
Hasegawa, M.1
Yamazaki, T.2
Kamada, N.3
Tawaratsumida, K.4
Kim, Y.G.5
Nunez, G.6
Inohara, N.7
-
30
-
-
84867605854
-
Critical role for MyD88-mediated neutrophil recruitment during Clostridium difficile colitis
-
Jarchum I, Liu M, Shi C, Equinda M, Pamer EG. 2012. Critical role for MyD88-mediated neutrophil recruitment during Clostridium difficile colitis. Infect Immun 80:2989-2996. http://dx.doi.org/10.1128/IAI.00448-12.
-
(2012)
Infect Immun
, vol.80
, pp. 2989-2996
-
-
Jarchum, I.1
Liu, M.2
Shi, C.3
Equinda, M.4
Pamer, E.G.5
-
31
-
-
79960938721
-
Bacterial resistance mechanisms against host defense peptides
-
Koprivnjak T, Peschel A. 2011. Bacterial resistance mechanisms against host defense peptides. Cell Mol Life Sci 68:2243-2254. http://dx.doi.org/10.1007/s00018-011-0716-4.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 2243-2254
-
-
Koprivnjak, T.1
Peschel, A.2
-
32
-
-
78650902755
-
Identification of a genetic locus responsible for antimicrobial peptide resistance in Clostridium difficile
-
McBride SM, Sonenshein AL. 2011. Identification of a genetic locus responsible for antimicrobial peptide resistance in Clostridium difficile. Infect Immun 79:167-176. http://dx.doi.org/10.1128/IAI.00731-10.
-
(2011)
Infect Immun
, vol.79
, pp. 167-176
-
-
McBride, S.M.1
Sonenshein, A.L.2
-
33
-
-
84870312026
-
Clostridium difficile clinical isolates exhibit variable susceptibility and proteome alterations upon exposure to mammalian cationic antimicrobial peptides
-
McQuade R, Roxas B, Viswanathan VK, Vedantam G. 2012. Clostridium difficile clinical isolates exhibit variable susceptibility and proteome alterations upon exposure to mammalian cationic antimicrobial peptides. Anaerobe 18:614-620. http://dx.doi.org/10.1016/j.anaerobe.2012.09.004.
-
(2012)
Anaerobe
, vol.18
, pp. 614-620
-
-
McQuade, R.1
Roxas, B.2
Viswanathan, V.K.3
Vedantam, G.4
-
35
-
-
70450267459
-
Diversity of moxifloxacin resistance during a nosocomial outbreak of a predominantly ribotype ARU 027 Clostridium difficile diarrhea
-
Carman RJ, Genheimer CW, Rafii F, Park M, Hiltonsmith MF, Lyerly DM. 2009. Diversity of moxifloxacin resistance during a nosocomial outbreak of a predominantly ribotype ARU 027 Clostridium difficile diarrhea. Anaerobe 15:244-248. http://dx.doi.org/10.1016/j.anaerobe.2009.09.009.
-
(2009)
Anaerobe
, vol.15
, pp. 244-248
-
-
Carman, R.J.1
Genheimer, C.W.2
Rafii, F.3
Park, M.4
Hiltonsmith, M.F.5
Lyerly, D.M.6
-
36
-
-
0030913746
-
Broad-spectrum antimicrobial activity of human intestinal defensin 5
-
Porter EM, van Dam E, Valore EV, Ganz T. 1997. Broad-spectrum antimicrobial activity of human intestinal defensin 5. Infect Immun 65: 2396-2401.
-
(1997)
Infect Immun
, vol.65
, pp. 2396-2401
-
-
Porter, E.M.1
van Dam, E.2
Valore, E.V.3
Ganz, T.4
-
37
-
-
0024391711
-
Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity
-
Lehrer RI, Barton A, Daher KA, Harwig SS, Ganz T, Selsted ME. 1989. Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity. J Clin Invest 84:553-561.
-
(1989)
J Clin Invest
, vol.84
, pp. 553-561
-
-
Lehrer, R.I.1
Barton, A.2
Daher, K.A.3
Harwig, S.S.4
Ganz, T.5
Selsted, M.E.6
-
38
-
-
33646003271
-
A flow cytometric assay to monitor antimicrobial activity of defensins and cationic tissue extracts
-
Nuding S, Fellermann K, Wehkamp J, Mueller HA, Stange EF. 2006. A flow cytometric assay to monitor antimicrobial activity of defensins and cationic tissue extracts. J Microbiol Methods 65:335-345. http://dx.doi.org/10.1016/j.mimet.2005.08.004.
-
(2006)
J Microbiol Methods
, vol.65
, pp. 335-345
-
-
Nuding, S.1
Fellermann, K.2
Wehkamp, J.3
Mueller, H.A.4
Stange, E.F.5
-
39
-
-
34249945094
-
Defensins and other antimicrobial peptides in inflammatory bowel disease
-
Wehkamp J, Schmid M, Stange EF. 2007. Defensins and other antimicrobial peptides in inflammatory bowel disease. Curr Opin Gastroenterol 23:370-378. http://dx.doi.org/10.1097/MOG.0b013e328136c580.
-
(2007)
Curr Opin Gastroenterol
, vol.23
, pp. 370-378
-
-
Wehkamp, J.1
Schmid, M.2
Stange, E.F.3
-
40
-
-
73649139991
-
Health careassociated Clostridium difficile infection in Canada: patient age and infecting strain type are highly predictive of severe outcome and mortality
-
Miller M, Gravel D, Mulvey M, Taylor G, Boyd D, Simor A, Gardam M, McGeer A, Hutchinson J, Moore D, Kelly S. 2010. Health careassociated Clostridium difficile infection in Canada: patient age and infecting strain type are highly predictive of severe outcome and mortality. Clin Infect Dis 50:194-201. http://dx.doi.org/10.1086/649213.
-
(2010)
Clin Infect Dis
, vol.50
, pp. 194-201
-
-
Miller, M.1
Gravel, D.2
Mulvey, M.3
Taylor, G.4
Boyd, D.5
Simor, A.6
Gardam, M.7
McGeer, A.8
Hutchinson, J.9
Moore, D.10
Kelly, S.11
-
41
-
-
34547697437
-
Emergence and control of fluoroquinolone-resistant, toxin A-negative, toxin B-positive Clostridium difficile
-
Drudy D, Harnedy N, Fanning S, Hannan M, Kyne L. 2007. Emergence and control of fluoroquinolone-resistant, toxin A-negative, toxin B-positive Clostridium difficile. Infect Control Hosp Epidemiol 28:932-940. http://dx.doi.org/10.1086/519181.
-
(2007)
Infect Control Hosp Epidemiol
, vol.28
, pp. 932-940
-
-
Drudy, D.1
Harnedy, N.2
Fanning, S.3
Hannan, M.4
Kyne, L.5
-
42
-
-
76249088522
-
Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium
-
Stabler RA, He M, Dawson L, Martin M, Valiente E, Corton C, Lawley TD, Sebaihia M, Quail MA, Rose G, Gerding DN, Gibert M, Popoff MR, Parkhill J, Dougan G, Wren BW. 2009. Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium. Genome Biol 10:R102. http://dx.doi.org/10.1186/gb-2009-10-9-r102.
-
(2009)
Genome Biol
, vol.10
, pp. R102
-
-
Stabler, R.A.1
He, M.2
Dawson, L.3
Martin, M.4
Valiente, E.5
Corton, C.6
Lawley, T.D.7
Sebaihia, M.8
Quail, M.A.9
Rose, G.10
Gerding, D.N.11
Gibert, M.12
Popoff, M.R.13
Parkhill, J.14
Dougan, G.15
Wren, B.W.16
-
43
-
-
77954581650
-
The changing epidemiology of Clostridium difficile infections
-
Freeman J, Bauer MP, Baines SD, Corver J, Fawley WN, Goorhuis B, Kuijper EJ, Wilcox MH. 2010. The changing epidemiology of Clostridium difficile infections. Clin Microbiol Rev 23:529-549. http://dx.doi.org/10.1128/CMR.00082-09.
-
(2010)
Clin Microbiol Rev
, vol.23
, pp. 529-549
-
-
Freeman, J.1
Bauer, M.P.2
Baines, S.D.3
Corver, J.4
Fawley, W.N.5
Goorhuis, B.6
Kuijper, E.J.7
Wilcox, M.H.8
-
44
-
-
34548130847
-
Reduced mucosal antimicrobial activity in Crohn's disease of the colon
-
Nuding S, Fellermann K, Wehkamp J, Stange EF. 2007. Reduced mucosal antimicrobial activity in Crohn's disease of the colon. Gut 56:1240-1247. http://dx.doi.org/10.1136/gut.2006.118646.
-
(2007)
Gut
, vol.56
, pp. 1240-1247
-
-
Nuding, S.1
Fellermann, K.2
Wehkamp, J.3
Stange, E.F.4
-
45
-
-
11244342346
-
Antibacterial activity and specificity of the six human α-defensins
-
Ericksen B, Wu Z, Lu W, Lehrer RI. 2005. Antibacterial activity and specificity of the six human α-defensins. Antimicrob Agents Chemother 49:269-275. http://dx.doi.org/10.1128/AAC.49.1.269-275.2005.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 269-275
-
-
Ericksen, B.1
Wu, Z.2
Lu, W.3
Lehrer, R.I.4
-
46
-
-
79955769157
-
The dlt operon confers resistance to cationic antimicrobial peptides in Clostridium difficile
-
McBride SM, Sonenshein AL. 2011. The dlt operon confers resistance to cationic antimicrobial peptides in Clostridium difficile. Microbiology 157:1457-1465. http://dx.doi.org/10.1099/mic.0.045997-0.
-
(2011)
Microbiology
, vol.157
, pp. 1457-1465
-
-
McBride, S.M.1
Sonenshein, A.L.2
-
47
-
-
0033915369
-
Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria
-
Friedrich CL, Moyles D, Beveridge TJ, Hancock RE. 2000. Antibacterial action of structurally diverse cationic peptides on gram-positive bacteria. Antimicrob Agents Chemother 44:2086-2092. http://dx.doi.org/10.1128/AAC.44.8.2086-2092.2000.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 2086-2092
-
-
Friedrich, C.L.1
Moyles, D.2
Beveridge, T.J.3
Hancock, R.E.4
-
48
-
-
0028878032
-
4(3)-), for the flow cytometric assessment of bacterial viability
-
4(3)-), for the flow cytometric assessment of bacterial viability. FEMS Microbiol Lett 130:165-169. http://dx.doi.org/10.1016/0378-1097(95)00199-F.
-
(1995)
FEMS Microbiol Lett
, vol.130
, pp. 165-169
-
-
Deere, D.1
Porter, J.2
Edwards, C.3
Pickup, R.4
-
49
-
-
62649119114
-
Antibacterial activity of human defensins on anaerobic intestinal bacterial species: a major role of HBD-3
-
Nuding S, Zabel LT, Enders C, Porter E, Fellermann K, Wehkamp J, Mueller HA, Stange EF. 2009. Antibacterial activity of human defensins on anaerobic intestinal bacterial species: a major role of HBD-3. Microbes Infect 11:384-393. http://dx.doi.org/10.1016/j.micinf.2009.01.001.
-
(2009)
Microbes Infect
, vol.11
, pp. 384-393
-
-
Nuding, S.1
Zabel, L.T.2
Enders, C.3
Porter, E.4
Fellermann, K.5
Wehkamp, J.6
Mueller, H.A.7
Stange, E.F.8
-
50
-
-
79961111087
-
PrsW is required for colonization, resistance to antimicrobial peptides, and expression of extracytoplasmic function sigma factors in Clostridium difficile
-
Ho TD, Ellermeier CD. 2011. PrsW is required for colonization, resistance to antimicrobial peptides, and expression of extracytoplasmic function sigma factors in Clostridium difficile. Infect Immun 79:3229-3238. http://dx.doi.org/10.1128/IAI.00019-11.
-
(2011)
Infect Immun
, vol.79
, pp. 3229-3238
-
-
Ho, T.D.1
Ellermeier, C.D.2
-
51
-
-
0037372643
-
Enteric salmonella infection inhibits Paneth cell antimicrobial peptide expression
-
Salzman NH, Chou MM, de Jong H, Liu L, Porter EM, Paterson Y. 2003. Enteric salmonella infection inhibits Paneth cell antimicrobial peptide expression. Infect Immun 71:1109-1115. http://dx.doi.org/10.1128/IAI.71.3.1109-1115.2003.
-
(2003)
Infect Immun
, vol.71
, pp. 1109-1115
-
-
Salzman, N.H.1
Chou, M.M.2
de Jong, H.3
Liu, L.4
Porter, E.M.5
Paterson, Y.6
-
52
-
-
70350437264
-
Alpha-defensins in enteric innate immunity: functional Paneth cell alpha-defensins in mouse colonic lumen
-
Mastroianni JR, Ouellette AJ. 2009. Alpha-defensins in enteric innate immunity: functional Paneth cell alpha-defensins in mouse colonic lumen. J Biol Chem 284:27848-27856. http://dx.doi.org/10.1074/jbc.M109.050773.
-
(2009)
J Biol Chem
, vol.284
, pp. 27848-27856
-
-
Mastroianni, J.R.1
Ouellette, A.J.2
-
53
-
-
33745217570
-
The co-evolution of host cationic antimicrobial peptides and microbial resistance
-
Peschel A, Sahl HG. 2006. The co-evolution of host cationic antimicrobial peptides and microbial resistance. Nat Rev Microbiol 4:529-536. http://dx.doi.org/10.1038/nrmicro1441.
-
(2006)
Nat Rev Microbiol
, vol.4
, pp. 529-536
-
-
Peschel, A.1
Sahl, H.G.2
-
54
-
-
67649295414
-
Biological activity and structural aspects of PGLa interaction with membrane mimetic systems
-
Lohner K, Prossnigg F. 2009. Biological activity and structural aspects of PGLa interaction with membrane mimetic systems. Biochim Biophys Acta 1788:1656-1666. http://dx.doi.org/10.1016/j.bbamem.2009.05.012.
-
(2009)
Biochim Biophys Acta
, vol.1788
, pp. 1656-1666
-
-
Lohner, K.1
Prossnigg, F.2
-
55
-
-
67649396451
-
Free energies of molecular bound states in lipid bilayers: lethal concentrations of antimicrobial peptides
-
Huang HW. 2009. Free energies of molecular bound states in lipid bilayers: lethal concentrations of antimicrobial peptides. Biophys J 96:3263-3272. http://dx.doi.org/10.1016/j.bpj.2009.01.030.
-
(2009)
Biophys J
, vol.96
, pp. 3263-3272
-
-
Huang, H.W.1
-
57
-
-
77955377305
-
Damage of the bacterial cell envelope by antimicrobial peptides gramicidin S and PGLa as revealed by transmission and scanning electron microscopy
-
Hartmann M, Berditsch M, Hawecker J, Ardakani MF, Gerthsen D, Ulrich AS. 2010. Damage of the bacterial cell envelope by antimicrobial peptides gramicidin S and PGLa as revealed by transmission and scanning electron microscopy. Antimicrob Agents Chemother 54:3132-3142. http://dx.doi.org/10.1128/AAC.00124-10.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 3132-3142
-
-
Hartmann, M.1
Berditsch, M.2
Hawecker, J.3
Ardakani, M.F.4
Gerthsen, D.5
Ulrich, A.S.6
-
58
-
-
84862679509
-
Functional determinants of human enteric alpha-defensin HD5: crucial role for hydrophobicity at dimer interface
-
Rajabi M, Ericksen B, Wu X, de Leeuw E, Zhao L, Pazgier M, Lu W. 2012. Functional determinants of human enteric alpha-defensin HD5: crucial role for hydrophobicity at dimer interface. J Biol Chem 287:21615-21627. http://dx.doi.org/10.1074/jbc.M112.367995.
-
(2012)
J Biol Chem
, vol.287
, pp. 21615-21627
-
-
Rajabi, M.1
Ericksen, B.2
Wu, X.3
de Leeuw, E.4
Zhao, L.5
Pazgier, M.6
Lu, W.7
-
59
-
-
0034252293
-
Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria
-
Ayabe T, Satchell DP, Wilson CL, Parks WC, Selsted ME, Ouellette AJ. 2000. Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria. Nat Immunol 1:113-118. http://dx.doi.org/10.1038/77783.
-
(2000)
Nat Immunol
, vol.1
, pp. 113-118
-
-
Ayabe, T.1
Satchell, D.P.2
Wilson, C.L.3
Parks, W.C.4
Selsted, M.E.5
Ouellette, A.J.6
-
60
-
-
0025694758
-
Detection of capsule in strains of Clostridium difficile of varying virulence and toxigenicity
-
Davies HA, Borriello SP. 1990. Detection of capsule in strains of Clostridium difficile of varying virulence and toxigenicity. Microb Pathog 9:141-146. http://dx.doi.org/10.1016/0882-4010(90)90088-8.
-
(1990)
Microb Pathog
, vol.9
, pp. 141-146
-
-
Davies, H.A.1
Borriello, S.P.2
-
61
-
-
0034971793
-
Molecular characterization of the surface layer proteins from Clostridium difficile
-
Calabi E, Ward S, Wren B, Paxton T, Panico M, Morris H, Dell A, Dougan G, Fairweather N. 2001. Molecular characterization of the surface layer proteins from Clostridium difficile. Mol Microbiol 40:1187-1199. http://dx.doi.org/10.1046/j.1365-2958.2001.02461.x.
-
(2001)
Mol Microbiol
, vol.40
, pp. 1187-1199
-
-
Calabi, E.1
Ward, S.2
Wren, B.3
Paxton, T.4
Panico, M.5
Morris, H.6
Dell, A.7
Dougan, G.8
Fairweather, N.9
-
62
-
-
44149126798
-
Secreted enteric antimicrobial activity localises to the mucus surface layer
-
Meyer-Hoffert U, Hornef MW, Henriques-Normark B, Axelsson LG, Midtvedt T, Putsep K, Andersson M. 2008. Secreted enteric antimicrobial activity localises to the mucus surface layer. Gut 57:764-771. http://dx.doi.org/10.1136/gut.2007.141481.
-
(2008)
Gut
, vol.57
, pp. 764-771
-
-
Meyer-Hoffert, U.1
Hornef, M.W.2
Henriques-Normark, B.3
Axelsson, L.G.4
Midtvedt, T.5
Putsep, K.6
Andersson, M.7
-
63
-
-
84873019302
-
Duodenal infusion of donor feces for recurrent Clostridium difficile
-
van Nood E, Vrieze A, Nieuwdorp M, Fuentes S, Zoetendal EG, de Vos WM, Visser CE, Kuijper EJ, Bartelsman JF, Tijssen JG, Speelman P, Dijkgraaf MG, Keller JJ. 2013. Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med 368:407-415. http://dx.doi.org/10.1056/NEJMoa1205037.
-
(2013)
N Engl J Med
, vol.368
, pp. 407-415
-
-
van Nood, E.1
Vrieze, A.2
Nieuwdorp, M.3
Fuentes, S.4
Zoetendal, E.G.5
de Vos, W.M.6
Visser, C.E.7
Kuijper, E.J.8
Bartelsman, J.F.9
Tijssen, J.G.10
Speelman, P.11
Dijkgraaf, M.G.12
Keller, J.J.13
-
64
-
-
79960936612
-
Multifunctional cationic host defence peptides and their clinical applications
-
Yeung AT, Gellatly SL, Hancock RE. 2011. Multifunctional cationic host defence peptides and their clinical applications. Cell Mol Life Sci 68:2161-2176. http://dx.doi.org/10.1007/s00018-011-0710-x.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 2161-2176
-
-
Yeung, A.T.1
Gellatly, S.L.2
Hancock, R.E.3
|