메뉴 건너뛰기




Volumn 90, Issue , 2018, Pages 1-27

The treatment of anti-phospholipid syndrome: A comprehensive clinical approach

Author keywords

Anti phospholipid antibodies; Anti phospholipid syndrome; Asymptomatic carriers; Catastrophic anti phospholipid syndrome; Obstetric complications; Thrombosis

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; ECULIZUMAB; HYDROXYCHLOROQUINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN; LOW MOLECULAR WEIGHT HEPARIN; RAPAMYCIN; RITUXIMAB; STEROID; TUMOR NECROSIS FACTOR INHIBITOR; ANTITHROMBOCYTIC AGENT; PHOSPHOLIPID ANTIBODY;

EID: 85041948348     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2018.02.003     Document Type: Review
Times cited : (56)

References (317)
  • 1
    • 33344458573 scopus 로고    scopus 로고
    • International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
    • Miyakis, S., Lockshin, M.D., Atsumi, T., Branch, D.W., Brey, R.L., Cervera, R., et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J. Thromb. Haemostasis 4 (2006), 295–306.
    • (2006) J. Thromb. Haemostasis , vol.4 , pp. 295-306
    • Miyakis, S.1    Lockshin, M.D.2    Atsumi, T.3    Branch, D.W.4    Brey, R.L.5    Cervera, R.6
  • 2
    • 77649232595 scopus 로고    scopus 로고
    • The geoepidemiology of the antiphospholipid antibody syndrome
    • Biggioggero, M., Meroni, P.L., The geoepidemiology of the antiphospholipid antibody syndrome. Autoimmun. Rev. 9 (2010), A299–A304.
    • (2010) Autoimmun. Rev. , vol.9 , pp. A299-A304
    • Biggioggero, M.1    Meroni, P.L.2
  • 4
    • 84925140284 scopus 로고    scopus 로고
    • (EUROAPS study group collaborators), the European registry on obstetric antiphospholipid syndrome (EUROAPS): a survey of 247 consecutive cases
    • Alijotas-Reig, J., Ferrer-Oliveras, R., Ruffatti, A., Tincani, A., Lefkou, E., Bertero, M.T., et al. (EUROAPS study group collaborators), the European registry on obstetric antiphospholipid syndrome (EUROAPS): a survey of 247 consecutive cases. Autoimmun. Rev. 14 (2015), 387–395.
    • (2015) Autoimmun. Rev. , vol.14 , pp. 387-395
    • Alijotas-Reig, J.1    Ferrer-Oliveras, R.2    Ruffatti, A.3    Tincani, A.4    Lefkou, E.5    Bertero, M.T.6
  • 5
    • 84861558865 scopus 로고    scopus 로고
    • Antibodies against domain I of β2-glycoprotein I: the one and only?
    • Pelkmans, L., de Laat, B., Antibodies against domain I of β2-glycoprotein I: the one and only?. Lupus 21 (2012), 769–772.
    • (2012) Lupus , vol.21 , pp. 769-772
    • Pelkmans, L.1    de Laat, B.2
  • 6
    • 84896702818 scopus 로고    scopus 로고
    • New tests to detect antiphospholipid antibodies: anti-domain I beta-2-glycoprotein-I antibodies
    • Chighizola, C.B., Gerosa, M., Meroni, P.L., New tests to detect antiphospholipid antibodies: anti-domain I beta-2-glycoprotein-I antibodies. Curr. Rheumatol. Rep. 16 (2014), 402–407.
    • (2014) Curr. Rheumatol. Rep. , vol.16 , pp. 402-407
    • Chighizola, C.B.1    Gerosa, M.2    Meroni, P.L.3
  • 8
    • 84899102723 scopus 로고    scopus 로고
    • Antiphospholipid syndrome in 2014: more clinical manifestations, novel pathogenic players and emerging biomarkers
    • Meroni, P.L., Chighizola, C.B., Rovelli, F., Gerosa, M., Antiphospholipid syndrome in 2014: more clinical manifestations, novel pathogenic players and emerging biomarkers. Arthritis Res. Ther., 16, 2014, 209.
    • (2014) Arthritis Res. Ther. , vol.16 , pp. 209
    • Meroni, P.L.1    Chighizola, C.B.2    Rovelli, F.3    Gerosa, M.4
  • 10
    • 84942581213 scopus 로고    scopus 로고
    • Update on the pathogenesis and treatment of the antiphospholipid syndrome
    • Chighizola, C.B., Raschi, E., Borghi, M.O., Meroni, P.L., Update on the pathogenesis and treatment of the antiphospholipid syndrome. Curr. Opin. Rheumatol. 27 (2015), 476–482.
    • (2015) Curr. Opin. Rheumatol. , vol.27 , pp. 476-482
    • Chighizola, C.B.1    Raschi, E.2    Borghi, M.O.3    Meroni, P.L.4
  • 12
    • 85044328539 scopus 로고    scopus 로고
    • Activated signature of antiphospholipid syndrome neutrophils reveals potential therapeutic target
    • Knight, J.S., Meng, H., Coit, P., Yalavarthi, S., Sule, G., Gandhi, A.A., et al. Activated signature of antiphospholipid syndrome neutrophils reveals potential therapeutic target. J.C.I. Insight, 21, 2017.
    • (2017) J.C.I. Insight , vol.21
    • Knight, J.S.1    Meng, H.2    Coit, P.3    Yalavarthi, S.4    Sule, G.5    Gandhi, A.A.6
  • 13
    • 22244485396 scopus 로고    scopus 로고
    • Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia
    • Pierangeli, S.S., Girardi, G., Vega-Ostertag, M., Liu, X., Espinola, R.G., Salmon, J., Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia. Arthritis Rheum. 52 (2005), 2120–2124.
    • (2005) Arthritis Rheum. , vol.52 , pp. 2120-2124
    • Pierangeli, S.S.1    Girardi, G.2    Vega-Ostertag, M.3    Liu, X.4    Espinola, R.G.5    Salmon, J.6
  • 14
    • 27144494245 scopus 로고    scopus 로고
    • Thrombus formation induced by antibodies to beta2-glycoprotein I is complement dependent and requires a priming factor
    • Fischetti, F., Durigutto, P., Pellis, V., Debeus, A., Macor, P., Bulla, R., et al. Thrombus formation induced by antibodies to beta2-glycoprotein I is complement dependent and requires a priming factor. Blood 106 (2005), 2340–2346.
    • (2005) Blood , vol.106 , pp. 2340-2346
    • Fischetti, F.1    Durigutto, P.2    Pellis, V.3    Debeus, A.4    Macor, P.5    Bulla, R.6
  • 15
    • 84901705578 scopus 로고    scopus 로고
    • A non-complement-fixing antibody to β2 glycoprotein I as a novel therapy for antiphospholipid syndrome
    • Agostinis, C., Durigutto, P., Sblattero, D., Borghi, M.O., Grossi, C., et al. A non-complement-fixing antibody to β2 glycoprotein I as a novel therapy for antiphospholipid syndrome. Blood 123 (2014), 3478–3487.
    • (2014) Blood , vol.123 , pp. 3478-3487
    • Agostinis, C.1    Durigutto, P.2    Sblattero, D.3    Borghi, M.O.4    Grossi, C.5
  • 16
    • 84908664176 scopus 로고    scopus 로고
    • Complement C5-inhibitor rEV576 (coversin) ameliorates in-vivo effects of antiphospholipid antibodies
    • Romay-Penabad, Z., Carrera Marin, A., Willis, R., Weston-Davies, W., Machin, S., Cohen, H., et al. Complement C5-inhibitor rEV576 (coversin) ameliorates in-vivo effects of antiphospholipid antibodies. Lupus 23 (2014), 1324–1326.
    • (2014) Lupus , vol.23 , pp. 1324-1326
    • Romay-Penabad, Z.1    Carrera Marin, A.2    Willis, R.3    Weston-Davies, W.4    Machin, S.5    Cohen, H.6
  • 17
    • 80054091683 scopus 로고    scopus 로고
    • In vivo distribution of β2 glycoprotein I under various pathophysiologic conditions
    • Agostinis, C., Biffi, S., Garrovo, C., Durigutto, P., Lorenzon, A., Bek, A., et al. In vivo distribution of β2 glycoprotein I under various pathophysiologic conditions. Blood 118 (2011), 4231–4238.
    • (2011) Blood , vol.118 , pp. 4231-4238
    • Agostinis, C.1    Biffi, S.2    Garrovo, C.3    Durigutto, P.4    Lorenzon, A.5    Bek, A.6
  • 18
    • 84926971910 scopus 로고    scopus 로고
    • Purified IgG from patients with obstetric but not IgG from non-obstetric antiphospholipid syndrome inhibit trophoblast invasion
    • Poulton, K., Ripoll, V.M., Pericleous, C., Meroni, P.L., Gerosa, M., Ioannou, Y., et al. Purified IgG from patients with obstetric but not IgG from non-obstetric antiphospholipid syndrome inhibit trophoblast invasion. Am. J. Reprod. Immunol. 73 (2015), 390–401.
    • (2015) Am. J. Reprod. Immunol. , vol.73 , pp. 390-401
    • Poulton, K.1    Ripoll, V.M.2    Pericleous, C.3    Meroni, P.L.4    Gerosa, M.5    Ioannou, Y.6
  • 19
    • 84925202181 scopus 로고    scopus 로고
    • Histopathology in the placentae of women with antiphospholipid antibodies: a systematic review of the literature
    • Viall, C.A., Chamley, L.W., Histopathology in the placentae of women with antiphospholipid antibodies: a systematic review of the literature. Autoimmun. Rev. 14 (2015), 446–471.
    • (2015) Autoimmun. Rev. , vol.14 , pp. 446-471
    • Viall, C.A.1    Chamley, L.W.2
  • 20
    • 85024858233 scopus 로고    scopus 로고
    • Emerging treatment models in rheumatology: antiphospholipid syndrome and pregnancy: pathogenesis to translation
    • Abrahams, V.M., Chamley, L.W., Salmon, J.E., Emerging treatment models in rheumatology: antiphospholipid syndrome and pregnancy: pathogenesis to translation. Arthritis Rheum. 69 (2017), 1710–1721.
    • (2017) Arthritis Rheum. , vol.69 , pp. 1710-1721
    • Abrahams, V.M.1    Chamley, L.W.2    Salmon, J.E.3
  • 21
    • 0028586742 scopus 로고
    • Reduction of annexin-V (placental anticoagulant protein-I) on placental villi of women with antiphospholipid antibodies and recurrent spontaneous abortion
    • Rand, J.H., Wu, X.X., Guller, S., Gil, J., Guha, A., Scher, J., Lockwood, C.J., Reduction of annexin-V (placental anticoagulant protein-I) on placental villi of women with antiphospholipid antibodies and recurrent spontaneous abortion. Am. J. Obstet. Gynecol. 171 (1994), 1566–1572.
    • (1994) Am. J. Obstet. Gynecol. , vol.171 , pp. 1566-1572
    • Rand, J.H.1    Wu, X.X.2    Guller, S.3    Gil, J.4    Guha, A.5    Scher, J.6    Lockwood, C.J.7
  • 22
    • 0030761057 scopus 로고    scopus 로고
    • Placental pathology and antiphospholipid antibodies: a descriptive study
    • Salafia, C.M., Cowchock, F.S., Placental pathology and antiphospholipid antibodies: a descriptive study. Am. J. Perinatol. 14 (1997), 435–441.
    • (1997) Am. J. Perinatol. , vol.14 , pp. 435-441
    • Salafia, C.M.1    Cowchock, F.S.2
  • 23
    • 0036117498 scopus 로고    scopus 로고
    • Defective endovascular trophoblast invasion in primary antiphospholipid antibody syndrome-associated early pregnancy failure
    • Sebire, N.J., Fox, H., Backos, M., Rai, R., Paterson, C., Regan, L., Defective endovascular trophoblast invasion in primary antiphospholipid antibody syndrome-associated early pregnancy failure. Hum. Reprod. 17 (2002), 1067–1071.
    • (2002) Hum. Reprod. , vol.17 , pp. 1067-1071
    • Sebire, N.J.1    Fox, H.2    Backos, M.3    Rai, R.4    Paterson, C.5    Regan, L.6
  • 24
    • 0031947185 scopus 로고    scopus 로고
    • Thrombotic storm: when thrombosis begets thrombosis
    • Kitchens, C.S., Thrombotic storm: when thrombosis begets thrombosis. Am. J. Med. 104 (1998), 381–385.
    • (1998) Am. J. Med. , vol.104 , pp. 381-385
    • Kitchens, C.S.1
  • 26
    • 84877043171 scopus 로고    scopus 로고
    • Platelet and endothelial activation in catastrophic and quiescent antiphospholipid syndrome
    • Bontadi, A., Ruffatti, A., Falcinelli, E., Giannini, S., Marturano, A., Tonello, M., et al. Platelet and endothelial activation in catastrophic and quiescent antiphospholipid syndrome. Thromb. Haemostasis 109 (2013), 901–908.
    • (2013) Thromb. Haemostasis , vol.109 , pp. 901-908
    • Bontadi, A.1    Ruffatti, A.2    Falcinelli, E.3    Giannini, S.4    Marturano, A.5    Tonello, M.6
  • 28
    • 84887108546 scopus 로고    scopus 로고
    • The hyperferritinemic syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid syndrome
    • Rosário, C., Zandman-Goddard, G., Meyron-Holtz, E.G., D'Cruz, D.P., Shoenfeld, Y., The hyperferritinemic syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid syndrome. BMC Med., 11, 2013, 185.
    • (2013) BMC Med. , vol.11 , pp. 185
    • Rosário, C.1    Zandman-Goddard, G.2    Meyron-Holtz, E.G.3    D'Cruz, D.P.4    Shoenfeld, Y.5
  • 29
    • 84866275320 scopus 로고    scopus 로고
    • Pathophysiology of thrombosis and pregnancy morbidity in the antiphospholipid syndrome
    • Oku, K., Amengual, O., Atsumi, T., Pathophysiology of thrombosis and pregnancy morbidity in the antiphospholipid syndrome. Eur. J. Clin. Invest. 42 (2012), 1126–1135.
    • (2012) Eur. J. Clin. Invest. , vol.42 , pp. 1126-1135
    • Oku, K.1    Amengual, O.2    Atsumi, T.3
  • 30
    • 33749118495 scopus 로고    scopus 로고
    • A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways
    • Ritis, K., Doumas, M., Mastellos, D., Micheli, A., Giaglis, S., Magotti, P., et al. A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways. J. Immunol. 177 (2006), 4794–4802.
    • (2006) J. Immunol. , vol.177 , pp. 4794-4802
    • Ritis, K.1    Doumas, M.2    Mastellos, D.3    Micheli, A.4    Giaglis, S.5    Magotti, P.6
  • 31
    • 0033958261 scopus 로고    scopus 로고
    • The role of infection in the pathogenesis of catastrophic antiphospholipid syndrome–molecular mimicry?
    • Asherson, R., Shoenfeld, Y., The role of infection in the pathogenesis of catastrophic antiphospholipid syndrome–molecular mimicry?. J. Rheumatol. 27 (2000), 12–14.
    • (2000) J. Rheumatol. , vol.27 , pp. 12-14
    • Asherson, R.1    Shoenfeld, Y.2
  • 32
    • 84995665659 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome (CAPS): descriptive analysis of 500 patients from the International CAPS Registry
    • Rodríguez-Pintó I., Moitinho, M., Santacreu, I., Shoenfeld, Y., Erkan, D., Espinosa, G., Cervera, R., Catastrophic antiphospholipid syndrome (CAPS): descriptive analysis of 500 patients from the International CAPS Registry. Autoimmun. Rev. 15 (2016), 1120–1124.
    • (2016) Autoimmun. Rev. , vol.15 , pp. 1120-1124
    • Rodríguez-Pintó, I.1    Moitinho, M.2    Santacreu, I.3    Shoenfeld, Y.4    Erkan, D.5    Espinosa, G.6    Cervera, R.7
  • 33
    • 84887112232 scopus 로고    scopus 로고
    • Estimated frequency of antiphospholipid antibodies in patients with pregnancy morbidity, stroke, myocardial infarction, and deep vein thrombosis: a critical review of the literature
    • Andreoli, L., Chighizola, C.B., Banzato, A., Pons-Estel, G.J., Ramires de Jesus, G., Erkan, D., Estimated frequency of antiphospholipid antibodies in patients with pregnancy morbidity, stroke, myocardial infarction, and deep vein thrombosis: a critical review of the literature. Arthritis Care Res. 65 (2013), 1869–1873.
    • (2013) Arthritis Care Res. , vol.65 , pp. 1869-1873
    • Andreoli, L.1    Chighizola, C.B.2    Banzato, A.3    Pons-Estel, G.J.4    Ramires de Jesus, G.5    Erkan, D.6
  • 34
    • 67649371944 scopus 로고    scopus 로고
    • Morbidity and mortality in the antiphospholipid syndrome during a 5-year period: a multicentre prospective study of 1000 patients
    • Cervera, R., Khamashta, M.A., Shoenfeld, Y., Camps, M.T., Jacobsen, S., Kiss, E., et al. Morbidity and mortality in the antiphospholipid syndrome during a 5-year period: a multicentre prospective study of 1000 patients. Ann. Rheum. Dis. 68 (2009), 1428–1432.
    • (2009) Ann. Rheum. Dis. , vol.68 , pp. 1428-1432
    • Cervera, R.1    Khamashta, M.A.2    Shoenfeld, Y.3    Camps, M.T.4    Jacobsen, S.5    Kiss, E.6
  • 35
    • 0036228886 scopus 로고    scopus 로고
    • Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients
    • Cervera, R., Piette, J.C., Font, J., Khamashta, M.A., Shoenfeld, Y., Camps, M.A.T., et al. Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients. Arthritis Rheum. 46 (2002), 1019–1027.
    • (2002) Arthritis Rheum. , vol.46 , pp. 1019-1027
    • Cervera, R.1    Piette, J.C.2    Font, J.3    Khamashta, M.A.4    Shoenfeld, Y.5    Camps, M.A.T.6
  • 37
    • 84948688029 scopus 로고    scopus 로고
    • Recognition and management of antiphospholipid syndrome
    • Gerosa, M., Meroni, P.L., Erkan, D., Recognition and management of antiphospholipid syndrome. Curr. Opin. Rheumatol. 28 (2016), 51–59.
    • (2016) Curr. Opin. Rheumatol. , vol.28 , pp. 51-59
    • Gerosa, M.1    Meroni, P.L.2    Erkan, D.3
  • 38
    • 79953304901 scopus 로고    scopus 로고
    • Antiphospholipid syndrome clinical research task force report
    • Erkan, D., Derksen, R., Levy, R., Machin, S., Ortel, T., Pierangeli, S., et al. Antiphospholipid syndrome clinical research task force report. Lupus 20 (2011), 219–224.
    • (2011) Lupus , vol.20 , pp. 219-224
    • Erkan, D.1    Derksen, R.2    Levy, R.3    Machin, S.4    Ortel, T.5    Pierangeli, S.6
  • 39
    • 85026999474 scopus 로고    scopus 로고
    • Prevalence and thrombotic risk assessment of anti-β2 glycoprotein I domain I antibodies: a systematic Review
    • Radin, M., Cecchi, I., Roccatello, D., Meroni, P.L., Sciascia, S., Prevalence and thrombotic risk assessment of anti-β2 glycoprotein I domain I antibodies: a systematic Review. Semin. Thromb. Hemost., 2017, 10.1055/s-0037–1603936.
    • (2017) Semin. Thromb. Hemost.
    • Radin, M.1    Cecchi, I.2    Roccatello, D.3    Meroni, P.L.4    Sciascia, S.5
  • 40
    • 61449186513 scopus 로고    scopus 로고
    • Risk factors for a first thrombotic event in antiphospholipid antibody carriers. A multicentre, retrospective follow-up study
    • Ruffatti, A., Del Ross, T., Ciprian, M., Nuzzo, M., Rampudda, M., Bertero, M.T., Bergia, R., Risk factors for a first thrombotic event in antiphospholipid antibody carriers. A multicentre, retrospective follow-up study. Ann. Rheum. Dis. 68 (2009), 397–399.
    • (2009) Ann. Rheum. Dis. , vol.68 , pp. 397-399
    • Ruffatti, A.1    Del Ross, T.2    Ciprian, M.3    Nuzzo, M.4    Rampudda, M.5    Bertero, M.T.6    Bergia, R.7
  • 41
    • 23844437705 scopus 로고    scopus 로고
    • A randomized clinical trial of high-intensity warfarin vs. conventional antithrombotic therapy for the prevention of recurrent thrombosis in patients with the antiphospholipid syndrome (WAPS)
    • Finazzi, G., Marchioli, R., Brancaccio, V., Schinco, P., Wisloff, F., Musial, J., et al. A randomized clinical trial of high-intensity warfarin vs. conventional antithrombotic therapy for the prevention of recurrent thrombosis in patients with the antiphospholipid syndrome (WAPS). J. Thromb. Haemostasis 3 (2005), 848–853.
    • (2005) J. Thromb. Haemostasis , vol.3 , pp. 848-853
    • Finazzi, G.1    Marchioli, R.2    Brancaccio, V.3    Schinco, P.4    Wisloff, F.5    Musial, J.6
  • 42
    • 37349061734 scopus 로고    scopus 로고
    • A systematic review of secondary thromboprophylaxis in patients with antiphospholipid antibodies
    • Ruiz-Irastorza, G., Hunt, B.J., Khamashta, M.A., A systematic review of secondary thromboprophylaxis in patients with antiphospholipid antibodies. Arthritis Rheum. 57 (2007), 1487–1495.
    • (2007) Arthritis Rheum. , vol.57 , pp. 1487-1495
    • Ruiz-Irastorza, G.1    Hunt, B.J.2    Khamashta, M.A.3
  • 43
    • 84964484527 scopus 로고    scopus 로고
    • Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people with antiphospholipid syndrome, Cochrane
    • Bala, M.M., Celinska-Lowenhoff, M., Szot, W., Padjas, A., Kaczmarczyk, M., Swierz, M.J., Undas, A., Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people with antiphospholipid syndrome, Cochrane. Database. Syst. Rev., 10, 2017, 10.1002/14651858.CD012169.pub2.
    • (2017) Database. Syst. Rev. , vol.10
    • Bala, M.M.1    Celinska-Lowenhoff, M.2    Szot, W.3    Padjas, A.4    Kaczmarczyk, M.5    Swierz, M.J.6    Undas, A.7
  • 44
    • 0141791073 scopus 로고    scopus 로고
    • A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome
    • Crowther, M.A., Ginsberg, J.S., Julian, J., Denburg, J., Hirsch, J., Douketis, J., et al. A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome. N. Engl. J. Med. 349 (2003), 1133–1138.
    • (2003) N. Engl. J. Med. , vol.349 , pp. 1133-1138
    • Crowther, M.A.1    Ginsberg, J.S.2    Julian, J.3    Denburg, J.4    Hirsch, J.5    Douketis, J.6
  • 45
    • 3042701142 scopus 로고    scopus 로고
    • Unreliability of international normalized ratio for monitoring warfarin therapy in patients with lupus anticoagulant
    • Rosborough, T.K., Shepherd, M.F., Unreliability of international normalized ratio for monitoring warfarin therapy in patients with lupus anticoagulant. Pharmacotherapy 24 (2004), 838–842.
    • (2004) Pharmacotherapy , vol.24 , pp. 838-842
    • Rosborough, T.K.1    Shepherd, M.F.2
  • 47
    • 85042118964 scopus 로고    scopus 로고
    • Anticoagulation withdrawal in antiphospholipid syndrome: a retrospective matched-control study
    • Yelnik, C.M., Urbanski, G., Drumez, E., Caron, C., Maillard, H., Morell-Dubois, S., et al. Anticoagulation withdrawal in antiphospholipid syndrome: a retrospective matched-control study. Lupus, 93, 2017, 10.1177/0961203317721751.
    • (2017) Lupus , vol.93
    • Yelnik, C.M.1    Urbanski, G.2    Drumez, E.3    Caron, C.4    Maillard, H.5    Morell-Dubois, S.6
  • 48
    • 0031919292 scopus 로고    scopus 로고
    • Anticardiolipin antibodies predict early recurrence of thromboembolism and death among patients with venous thromboembolism following anticoagulant therapy. Duration of Anticoagulation Study Group
    • Schulman, S., Svenungsson, E., Granqvist, S., Anticardiolipin antibodies predict early recurrence of thromboembolism and death among patients with venous thromboembolism following anticoagulant therapy. Duration of Anticoagulation Study Group. Am. J. Med. 104 (1998), 332–338.
    • (1998) Am. J. Med. , vol.104 , pp. 332-338
    • Schulman, S.1    Svenungsson, E.2    Granqvist, S.3
  • 49
    • 85027473271 scopus 로고    scopus 로고
    • Anti-phospholipid Piedemont Consortium, Thrombotic recurrences and bleeding events in APS vascular patients: a review from the literature and a comparison with the APS Piedmont Cohort
    • Bazzan, M., Vaccarino, A., Stella, S., Bertero, M.T., Carignola, R., Montaruli, B., et al. Anti-phospholipid Piedemont Consortium, Thrombotic recurrences and bleeding events in APS vascular patients: a review from the literature and a comparison with the APS Piedmont Cohort. Autoimmun. Rev. 12 (2013), 26–31.
    • (2013) Autoimmun. Rev. , vol.12 , pp. 26-31
    • Bazzan, M.1    Vaccarino, A.2    Stella, S.3    Bertero, M.T.4    Carignola, R.5    Montaruli, B.6
  • 50
    • 84886379226 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and the risk of recurrence after a first episode of venous thromboembolism: a systematic review
    • Garcia, D., Akl, E.A., Carr, R., Kearon, C., Antiphospholipid antibodies and the risk of recurrence after a first episode of venous thromboembolism: a systematic review. Blood 122 (2013), 817–824.
    • (2013) Blood , vol.122 , pp. 817-824
    • Garcia, D.1    Akl, E.A.2    Carr, R.3    Kearon, C.4
  • 51
    • 84879549586 scopus 로고    scopus 로고
    • Discontinuation of anticoagulation or antiaggregation treatment may be safe in patients with primary antiphospholipid syndrome when antiphospholipid antibodies became persistently negative
    • Coloma Bazán, E., Donate López, C., Moreno Lozano, P., Cervera, R., Espinosa, G., Discontinuation of anticoagulation or antiaggregation treatment may be safe in patients with primary antiphospholipid syndrome when antiphospholipid antibodies became persistently negative. Immunol. Res. 56 (2013), 358–361.
    • (2013) Immunol. Res. , vol.56 , pp. 358-361
    • Coloma Bazán, E.1    Donate López, C.2    Moreno Lozano, P.3    Cervera, R.4    Espinosa, G.5
  • 53
    • 85046587675 scopus 로고    scopus 로고
    • Recurrent thrombosis in patients with antiphospholipid antibodies and arterial thrombosis on antithrombotic therapy
    • Jackson, W.G., Oromendia, C., Unlu, O., Erkan, D., DeSancho, M.T., Recurrent thrombosis in patients with antiphospholipid antibodies and arterial thrombosis on antithrombotic therapy. Blood. Adv. 1 (2017), 2320–2324.
    • (2017) Blood. Adv. , vol.1 , pp. 2320-2324
    • Jackson, W.G.1    Oromendia, C.2    Unlu, O.3    Erkan, D.4    DeSancho, M.T.5
  • 54
    • 67049109432 scopus 로고    scopus 로고
    • Clinical manifestations and outcomes of antithrombotic treatment of the Tan Tock Seng Hospital Singapore antiphospholipid syndrome cohort
    • Tan, B.E., Thong, B.Y.H., Shivananda, S., Han, W.W., Chng, H.H., Clinical manifestations and outcomes of antithrombotic treatment of the Tan Tock Seng Hospital Singapore antiphospholipid syndrome cohort. Lupus 18 (2009), 752–775.
    • (2009) Lupus , vol.18 , pp. 752-775
    • Tan, B.E.1    Thong, B.Y.H.2    Shivananda, S.3    Han, W.W.4    Chng, H.H.5
  • 56
    • 85046601191 scopus 로고    scopus 로고
    • The risk of ischaemic stroke in primary antiphospholipid syndrome patients: a prospective study
    • Radin, M., Schreiber, K., Cecchi, I., Roccatello, D., Cuadrado, M.J., Sciascia, S., The risk of ischaemic stroke in primary antiphospholipid syndrome patients: a prospective study. Eur. J. Neurol. 4 (2017), 295–299.
    • (2017) Eur. J. Neurol. , vol.4 , pp. 295-299
    • Radin, M.1    Schreiber, K.2    Cecchi, I.3    Roccatello, D.4    Cuadrado, M.J.5    Sciascia, S.6
  • 57
    • 34547407889 scopus 로고    scopus 로고
    • Aspirin for primary thrombosis prevention in the antiphospholipid syndrome: a randomized, double-blind, placebo-controlled trial in asymptomatic antiphospholipid antibody-positive individuals
    • Erkan, D., Harrison, M.J., Levy, R., Peterson, M., Petri, M., Sammaritano, L., et al. Aspirin for primary thrombosis prevention in the antiphospholipid syndrome: a randomized, double-blind, placebo-controlled trial in asymptomatic antiphospholipid antibody-positive individuals. Arthritis Rheum. 56 (2007), 2382–2391.
    • (2007) Arthritis Rheum. , vol.56 , pp. 2382-2391
    • Erkan, D.1    Harrison, M.J.2    Levy, R.3    Peterson, M.4    Petri, M.5    Sammaritano, L.6
  • 58
    • 84934930787 scopus 로고    scopus 로고
    • Euro-Phospholipid Project Group (European Forum on Antiphospholipid Antibodies), Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: a multicentre prospective study of 1000 patients
    • Cervera, R., Serrano, R., Pons-Estel, G.J., Ceberio-Hualde, L., Shoenfeld, Y., de Ramon, E., et al. Euro-Phospholipid Project Group (European Forum on Antiphospholipid Antibodies), Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: a multicentre prospective study of 1000 patients. Ann. Rheum. Dis. 74 (2015), 1011–1018.
    • (2015) Ann. Rheum. Dis. , vol.74 , pp. 1011-1018
    • Cervera, R.1    Serrano, R.2    Pons-Estel, G.J.3    Ceberio-Hualde, L.4    Shoenfeld, Y.5    de Ramon, E.6
  • 60
    • 48749104624 scopus 로고    scopus 로고
    • Hydroxychloroquine directly reduces the binding of antiphospholipid antibody-beta2-glycoprotein I complexes to phospholipid bilayers
    • Rand, J.H., Wu, X.-X., Quinn, A.S., Chen, P.P., Hathcock, J.J., Taatjes, D.J., Hydroxychloroquine directly reduces the binding of antiphospholipid antibody-beta2-glycoprotein I complexes to phospholipid bilayers. Blood 112 (2008), 1687–1695.
    • (2008) Blood , vol.112 , pp. 1687-1695
    • Rand, J.H.1    Wu, X.-X.2    Quinn, A.S.3    Chen, P.P.4    Hathcock, J.J.5    Taatjes, D.J.6
  • 61
    • 77950435764 scopus 로고    scopus 로고
    • Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: evidence for a novel effect for an old antimalarial drug
    • Rand, J.H., Wu, X.-X., Quinn, A.S., Ashton, A.W., Chen, P.P., Hathcock, J.J., Andree, H.A., Taatjes, D.J., Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: evidence for a novel effect for an old antimalarial drug. Blood 115 (2010), 2292–2299.
    • (2010) Blood , vol.115 , pp. 2292-2299
    • Rand, J.H.1    Wu, X.-X.2    Quinn, A.S.3    Ashton, A.W.4    Chen, P.P.5    Hathcock, J.J.6    Andree, H.A.7    Taatjes, D.J.8
  • 62
    • 85032809119 scopus 로고    scopus 로고
    • Antiphospholipid antibody-induced cellular responses depend on epitope specificity: implications for treatment of antiphospholipid syndrome
    • Müller-Calleja, N., Hollerbach, A., Häuser, F., Canisius, A., Orning, C., Lackner, K.J., Antiphospholipid antibody-induced cellular responses depend on epitope specificity: implications for treatment of antiphospholipid syndrome. J. Thromb. Haemostasis 15 (2017), 2367–2376.
    • (2017) J. Thromb. Haemostasis , vol.15 , pp. 2367-2376
    • Müller-Calleja, N.1    Hollerbach, A.2    Häuser, F.3    Canisius, A.4    Orning, C.5    Lackner, K.J.6
  • 63
    • 0036123462 scopus 로고    scopus 로고
    • Hydroxychloroquine reverses platelet activation induced by human IgG antiphospholipid antibodies
    • Espinola, R.G., Pierangeli, S.S., Gharavi, A.E., Harris, E.N., Ghara, A.E., Hydroxychloroquine reverses platelet activation induced by human IgG antiphospholipid antibodies. Thromb. Haemostasis 87 (2002), 518–522.
    • (2002) Thromb. Haemostasis , vol.87 , pp. 518-522
    • Espinola, R.G.1    Pierangeli, S.S.2    Gharavi, A.E.3    Harris, E.N.4    Ghara, A.E.5
  • 64
    • 0031442025 scopus 로고    scopus 로고
    • Hydroxychloroquine reverses thrombogenic properties of antiphospholipid antibodies in mice
    • Edwards, M.H., Pierangeli, S., Liu, X., Barker, J.H., Anderson, G., Harris, E.N., Hydroxychloroquine reverses thrombogenic properties of antiphospholipid antibodies in mice. Circulation 96 (1997), 4380–4384.
    • (1997) Circulation , vol.96 , pp. 4380-4384
    • Edwards, M.H.1    Pierangeli, S.2    Liu, X.3    Barker, J.H.4    Anderson, G.5    Harris, E.N.6
  • 65
    • 79551544891 scopus 로고    scopus 로고
    • Use of hydroxychloroquine to prevent thrombosis in systemic lupus erythematosus and in antiphospholipid antibody-positive patients
    • Petri, M., Use of hydroxychloroquine to prevent thrombosis in systemic lupus erythematosus and in antiphospholipid antibody-positive patients. Curr. Rheumatol. Rep. 13 (2011), 77–80.
    • (2011) Curr. Rheumatol. Rep. , vol.13 , pp. 77-80
    • Petri, M.1
  • 66
    • 58349097555 scopus 로고    scopus 로고
    • Risk factors for thrombosis and primary thrombosis prevention in patients with systemic lupus erythematosus with or without antiphospholipid antibodies
    • Tektonidou, M.G., Laskari, K., Panagiotakos, D.B., Moutsopoulos, H.M., Risk factors for thrombosis and primary thrombosis prevention in patients with systemic lupus erythematosus with or without antiphospholipid antibodies. Arthritis Rheum. 61 (2009), 29–36.
    • (2009) Arthritis Rheum. , vol.61 , pp. 29-36
    • Tektonidou, M.G.1    Laskari, K.2    Panagiotakos, D.B.3    Moutsopoulos, H.M.4
  • 68
    • 84978085781 scopus 로고    scopus 로고
    • Long-term use of hydroxychloroquine reduces antiphospholipid antibodies levels in patients with primary antiphospholipid syndrome
    • Nuri, E., Taraborelli, M., Andreoli, L., Tonello, M., Gerosa, M., Calligaro, A., et al. Long-term use of hydroxychloroquine reduces antiphospholipid antibodies levels in patients with primary antiphospholipid syndrome. Immunol. Res. 65 (2017), 17–24.
    • (2017) Immunol. Res. , vol.65 , pp. 17-24
    • Nuri, E.1    Taraborelli, M.2    Andreoli, L.3    Tonello, M.4    Gerosa, M.5    Calligaro, A.6
  • 69
    • 84864386925 scopus 로고    scopus 로고
    • B-cell directed therapies in antiphospholipid antibody syndrome-new directions based on murine and human data
    • Khattri, S., Zandman-Goddard, G., Peeva, E., B-cell directed therapies in antiphospholipid antibody syndrome-new directions based on murine and human data. Autoimmun. Rev. 11 (2012), 717–722.
    • (2012) Autoimmun. Rev. , vol.11 , pp. 717-722
    • Khattri, S.1    Zandman-Goddard, G.2    Peeva, E.3
  • 70
    • 84873846125 scopus 로고    scopus 로고
    • A pilot open-label phase II trial of rituximab for non-criteria manifestations of antiphospholipid syndrome
    • Erkan, D., Vega, J., Ramón, G., Kozora, E., Lockshin, M.D., A pilot open-label phase II trial of rituximab for non-criteria manifestations of antiphospholipid syndrome. Arthritis Rheum. 65 (2013), 464–471.
    • (2013) Arthritis Rheum. , vol.65 , pp. 464-471
    • Erkan, D.1    Vega, J.2    Ramón, G.3    Kozora, E.4    Lockshin, M.D.5
  • 71
    • 84896544929 scopus 로고    scopus 로고
    • 14th international congress on antiphospholipid antibodies task force report on antiphospholipid syndrome treatment trends
    • Erkan, D., Aguiar, C.L., Andrade, D., Cohen, H., Cuadrado, M.J., Danowski, A., et al. 14th international congress on antiphospholipid antibodies task force report on antiphospholipid syndrome treatment trends. Autoimmun. Rev. 13 (2014), 685–696.
    • (2014) Autoimmun. Rev. , vol.13 , pp. 685-696
    • Erkan, D.1    Aguiar, C.L.2    Andrade, D.3    Cohen, H.4    Cuadrado, M.J.5    Danowski, A.6
  • 73
    • 84958185001 scopus 로고    scopus 로고
    • Complement activation in antiphospholipid syndrome and its inhibition to prevent rethrombosis after arterial surgery
    • Meroni, P.L., Macor, P., Durigutto, P., De Maso, L., Gerosa, M., Ferraresso, M., et al. Complement activation in antiphospholipid syndrome and its inhibition to prevent rethrombosis after arterial surgery. Blood 127 (2016), 365–367.
    • (2016) Blood , vol.127 , pp. 365-367
    • Meroni, P.L.1    Macor, P.2    Durigutto, P.3    De Maso, L.4    Gerosa, M.5    Ferraresso, M.6
  • 74
    • 84929650173 scopus 로고    scopus 로고
    • Treatment of thrombotic antiphospholipid syndrome: the Rationale of current management- an insight into future approaches
    • 951424–20volume: 2015; year: 2015; article ID: 951424, page range: 1-20
    • Chighizola, C.B., Ubiali, T., Meroni, P.L., Treatment of thrombotic antiphospholipid syndrome: the Rationale of current management- an insight into future approaches. J. Immunol. Res., 2015 951424–20volume: 2015; year: 2015; article ID: 951424, page range: 1-20.
    • (2015) J. Immunol. Res.
    • Chighizola, C.B.1    Ubiali, T.2    Meroni, P.L.3
  • 75
    • 84958850685 scopus 로고    scopus 로고
    • Intravenous immunoglobulins and antiphospholipid syndrome: how, when and why? A review of the literature
    • Tenti, S., Cheleschi, S., Guidelli, G.M., Galeazzi, M., Fioravanti, A., Intravenous immunoglobulins and antiphospholipid syndrome: how, when and why? A review of the literature. Autoimmun. Rev. 15 (2016), 226–235.
    • (2016) Autoimmun. Rev. , vol.15 , pp. 226-235
    • Tenti, S.1    Cheleschi, S.2    Guidelli, G.M.3    Galeazzi, M.4    Fioravanti, A.5
  • 76
    • 84864749163 scopus 로고    scopus 로고
    • Prevention of thrombosis relapse in antiphospholipid syndrome patients refractory to conventional therapy using intravenous immunoglobulin
    • Sciascia, S., Giachino, O., Roccatello, D., Prevention of thrombosis relapse in antiphospholipid syndrome patients refractory to conventional therapy using intravenous immunoglobulin. Clin. Exp. Rheumatol. 30 (2012), 409–413.
    • (2012) Clin. Exp. Rheumatol. , vol.30 , pp. 409-413
    • Sciascia, S.1    Giachino, O.2    Roccatello, D.3
  • 78
    • 84991661576 scopus 로고    scopus 로고
    • Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial
    • Cohen, H., Hunt, B.J., Efthymiou, M., Arachchillage, D.R.J., Mackie, I.J., Clawson, S., et al. Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial. Lancet. Haematol. 3 (2016), e426–e436.
    • (2016) Lancet. Haematol. , vol.3 , pp. e426-e436
    • Cohen, H.1    Hunt, B.J.2    Efthymiou, M.3    Arachchillage, D.R.J.4    Mackie, I.J.5    Clawson, S.6
  • 79
    • 85042068391 scopus 로고    scopus 로고
    • Protocol modification of apixaban for the secondary prevention of thrombosis among patients with antiphospholipid syndrome study
    • Woller, S.C., Stevens, S.M., Kaplan, D.A., T Rondina, M., Protocol modification of apixaban for the secondary prevention of thrombosis among patients with antiphospholipid syndrome study. Clin. Appl. Thromb. Hemost., 24, 2018, 192.
    • (2018) Clin. Appl. Thromb. Hemost. , vol.24 , pp. 192
    • Woller, S.C.1    Stevens, S.M.2    Kaplan, D.A.3    T Rondina, M.4
  • 80
    • 85027933204 scopus 로고    scopus 로고
    • Rivaroxaban as an effective treatment for recurrent superficial thrombophlebitis related to primary antiphospholipid syndrome
    • Bachmeyer, C., Elalamy, I., Rivaroxaban as an effective treatment for recurrent superficial thrombophlebitis related to primary antiphospholipid syndrome. Clin. Exp. Dermatol. 39 (2014), 840–841.
    • (2014) Clin. Exp. Dermatol. , vol.39 , pp. 840-841
    • Bachmeyer, C.1    Elalamy, I.2
  • 81
    • 84907994966 scopus 로고    scopus 로고
    • New oral anticoagulants may not be effective to prevent venous thromboembolism in patients with antiphospholipid syndrome
    • Win, K., Rodgers, G.M., New oral anticoagulants may not be effective to prevent venous thromboembolism in patients with antiphospholipid syndrome. Am. J. Hematol., 89, 2014, 1017.
    • (2014) Am. J. Hematol. , vol.89 , pp. 1017
    • Win, K.1    Rodgers, G.M.2
  • 82
    • 84908550562 scopus 로고    scopus 로고
    • Failure of dabigatran and rivaroxaban to prevent thromboembolism in antiphospholipid syndrome: a case series of three patients
    • Schaefer, J.K., McBane, R.D., Black, D.F., Williams, L.N., Moder, K.G., Wysokinski, W.E., Failure of dabigatran and rivaroxaban to prevent thromboembolism in antiphospholipid syndrome: a case series of three patients. Thromb. Haemostasis 112 (2014), 947–950.
    • (2014) Thromb. Haemostasis , vol.112 , pp. 947-950
    • Schaefer, J.K.1    McBane, R.D.2    Black, D.F.3    Williams, L.N.4    Moder, K.G.5    Wysokinski, W.E.6
  • 83
    • 84930759043 scopus 로고    scopus 로고
    • Safety and efficacy of oral direct inhibitors of thrombin and factor Xa in antiphospholipid syndrome
    • Noel, N., Dutasta, F., Costedoat-Chalumeau, N., Bienvenu, B., Mariette, X., Geffray, L., et al. Safety and efficacy of oral direct inhibitors of thrombin and factor Xa in antiphospholipid syndrome. Autoimmun. Rev. 14 (2015), 680–685.
    • (2015) Autoimmun. Rev. , vol.14 , pp. 680-685
    • Noel, N.1    Dutasta, F.2    Costedoat-Chalumeau, N.3    Bienvenu, B.4    Mariette, X.5    Geffray, L.6
  • 84
    • 84937637849 scopus 로고    scopus 로고
    • Recurrent lacunar ischaemic stroke due to resistance to antiplatelet treatment: examining the need for personalised antithrombotic therapy
    • Delgado, M.G., Corte, J.R., Sáiz, A., Calleja, S., Recurrent lacunar ischaemic stroke due to resistance to antiplatelet treatment: examining the need for personalised antithrombotic therapy. Neurologia 30 (2015), 376–378.
    • (2015) Neurologia , vol.30 , pp. 376-378
    • Delgado, M.G.1    Corte, J.R.2    Sáiz, A.3    Calleja, S.4
  • 85
    • 84948983807 scopus 로고    scopus 로고
    • Cerebral venous thromboembolism in antiphospholipid syndrome successfully treated with the combined use of an anti-Xa inhibitor and corticosteroid
    • Sugie, M., Iizuka, N., Shimizu, Y., Ichikawa, H., Cerebral venous thromboembolism in antiphospholipid syndrome successfully treated with the combined use of an anti-Xa inhibitor and corticosteroid. Intern. Med. 54 (2015), 3051–3056.
    • (2015) Intern. Med. , vol.54 , pp. 3051-3056
    • Sugie, M.1    Iizuka, N.2    Shimizu, Y.3    Ichikawa, H.4
  • 86
    • 84929471149 scopus 로고    scopus 로고
    • Rivaroxaban use in patients with antiphospholipid syndrome and previous venous thromboembolism
    • Sciascia, S., Breen, K., Hunt, B.J., Rivaroxaban use in patients with antiphospholipid syndrome and previous venous thromboembolism. Blood Coagul. Fibrinolysis 26 (2015), 476–477.
    • (2015) Blood Coagul. Fibrinolysis , vol.26 , pp. 476-477
    • Sciascia, S.1    Breen, K.2    Hunt, B.J.3
  • 87
    • 85046594013 scopus 로고    scopus 로고
    • The use of rivaroxaban in patients with antiphospholipid syndrome: a series of 12 cases
    • Son, M., Wypasek, E., Celinska-Lowenhoff, M., Undas, A., The use of rivaroxaban in patients with antiphospholipid syndrome: a series of 12 cases. Thromb. Res., 1, 2015, 2.
    • (2015) Thromb. Res. , vol.1 , pp. 2
    • Son, M.1    Wypasek, E.2    Celinska-Lowenhoff, M.3    Undas, A.4
  • 88
    • 84960434570 scopus 로고    scopus 로고
    • Thrombotic events in patients with antiphospholipid syndrome treated with rivaroxaban: a series of eight cases
    • Signorelli, F., Nogueira, F., Domingues, V., Mariz, H.A., Levy, R.A., Thrombotic events in patients with antiphospholipid syndrome treated with rivaroxaban: a series of eight cases. Clin. Rheumatol. 35 (2016), 801–805.
    • (2016) Clin. Rheumatol. , vol.35 , pp. 801-805
    • Signorelli, F.1    Nogueira, F.2    Domingues, V.3    Mariz, H.A.4    Levy, R.A.5
  • 90
    • 84977640609 scopus 로고    scopus 로고
    • Bipolar disorder, ischemic stroke, mitral valve vegetation and recurrent venous thrombosis due to antiphospholipid syndrome despite rivaroxaban
    • Rokos, J., Heger, M., Stöllberger, C., Finsterer, J., Laufer, G., Wiedemann, D., Bipolar disorder, ischemic stroke, mitral valve vegetation and recurrent venous thrombosis due to antiphospholipid syndrome despite rivaroxaban. Int. J. Cardiol. 221 (2016), 383–384.
    • (2016) Int. J. Cardiol. , vol.221 , pp. 383-384
    • Rokos, J.1    Heger, M.2    Stöllberger, C.3    Finsterer, J.4    Laufer, G.5    Wiedemann, D.6
  • 91
    • 84979272518 scopus 로고    scopus 로고
    • Rivaroxaban - a safe therapeutic option in patients with antiphospholipid syndrome? Our experience in 23 cases
    • Haładyj, E., Olesińska, M., Rivaroxaban - a safe therapeutic option in patients with antiphospholipid syndrome? Our experience in 23 cases. Reumatologia 54 (2016), 146–149.
    • (2016) Reumatologia , vol.54 , pp. 146-149
    • Haładyj, E.1    Olesińska, M.2
  • 92
    • 85021733216 scopus 로고    scopus 로고
    • Direct oral anticoagulants: an alternative treatment for thrombotic antiphospholipid syndrome?
    • Resseguier, A.S., Pereira, B., Rieu, V., Le Guenno, G., Grobost, V., Ruivard, M., Direct oral anticoagulants: an alternative treatment for thrombotic antiphospholipid syndrome?. Lupus 26 (2017), 1297–1303.
    • (2017) Lupus , vol.26 , pp. 1297-1303
    • Resseguier, A.S.1    Pereira, B.2    Rieu, V.3    Le Guenno, G.4    Grobost, V.5    Ruivard, M.6
  • 94
    • 85026451069 scopus 로고    scopus 로고
    • Recurrent thrombosis in patients with antiphospholipid syndrome receiving newer oral anticoagulants: a case report and review of literature
    • Joshi, A., Hong, J., Siva, C., Recurrent thrombosis in patients with antiphospholipid syndrome receiving newer oral anticoagulants: a case report and review of literature. Clin. Med. Res. 15 (2017), 41–44.
    • (2017) Clin. Med. Res. , vol.15 , pp. 41-44
    • Joshi, A.1    Hong, J.2    Siva, C.3
  • 95
    • 85008414264 scopus 로고    scopus 로고
    • The use of direct oral anticoagulants in 56 patients with antiphospholipid syndrome
    • Malec, K., Góralczyk, T., Undas, A., The use of direct oral anticoagulants in 56 patients with antiphospholipid syndrome. Thromb. Res. 152 (2017), 93–97.
    • (2017) Thromb. Res. , vol.152 , pp. 93-97
    • Malec, K.1    Góralczyk, T.2    Undas, A.3
  • 96
    • 85015707473 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome on switching from warfarin to rivaroxaban
    • Crowley, M.P., Cuadrado, M.J., Hunt, B.J., Catastrophic antiphospholipid syndrome on switching from warfarin to rivaroxaban. Thromb. Res. 153 (2017), 37–39.
    • (2017) Thromb. Res. , vol.153 , pp. 37-39
    • Crowley, M.P.1    Cuadrado, M.J.2    Hunt, B.J.3
  • 98
    • 84982976138 scopus 로고    scopus 로고
    • Stents coated with mammalian target of rapamycin inhibitors (mTOR) appear to be the best choice in patients with antiphospholipid syndrome and myocardial infarction
    • Mora-Ramírez, M., González-Pacheco, H., Amezcua-Guerra, L.M., Stents coated with mammalian target of rapamycin inhibitors (mTOR) appear to be the best choice in patients with antiphospholipid syndrome and myocardial infarction. J. Clin. Rheumatol., 22, 2016, 281.
    • (2016) J. Clin. Rheumatol. , vol.22 , pp. 281
    • Mora-Ramírez, M.1    González-Pacheco, H.2    Amezcua-Guerra, L.M.3
  • 101
    • 80051936498 scopus 로고    scopus 로고
    • Risk factors for pregnancy failure in patients with anti-phospholipid syndrome treated with conventional therapies: a multicentre, case-control study
    • Ruffatti, A., Tonello, M., Visentin, M.S., Bontadi, A., Hoxha, A., de Carolis, S., et al. Risk factors for pregnancy failure in patients with anti-phospholipid syndrome treated with conventional therapies: a multicentre, case-control study. Rheumatology 50 (2011), 1684–1689.
    • (2011) Rheumatology , vol.50 , pp. 1684-1689
    • Ruffatti, A.1    Tonello, M.2    Visentin, M.S.3    Bontadi, A.4    Hoxha, A.5    de Carolis, S.6
  • 102
    • 33748597665 scopus 로고    scopus 로고
    • Antibody profile and clinical course in primary antiphospholipid syndrome with pregnancy morbidity
    • Ruffatti, A., Tonello, M., del Ross, T., Cavazzana, A., Grava, C., Noventa, F., et al. Antibody profile and clinical course in primary antiphospholipid syndrome with pregnancy morbidity. Thromb. Haemostasis 96 (2006), 337–341.
    • (2006) Thromb. Haemostasis , vol.96 , pp. 337-341
    • Ruffatti, A.1    Tonello, M.2    del Ross, T.3    Cavazzana, A.4    Grava, C.5    Noventa, F.6
  • 103
    • 85023198961 scopus 로고    scopus 로고
    • Pregnancy failure in patients with obstetric antiphospholipid syndrome with conventional treatment: the influence of a triple positive antibody profile
    • Latino, J.O., Udry, S., Aranda, F.M., Perés Wingeyer, S.D.A., Fernández Romero, D.S., de Larrañaga, G.F., Pregnancy failure in patients with obstetric antiphospholipid syndrome with conventional treatment: the influence of a triple positive antibody profile. Lupus 26 (2017), 983–988.
    • (2017) Lupus , vol.26 , pp. 983-988
    • Latino, J.O.1    Udry, S.2    Aranda, F.M.3    Perés Wingeyer, S.D.A.4    Fernández Romero, D.S.5    de Larrañaga, G.F.6
  • 104
    • 84961212573 scopus 로고    scopus 로고
    • Maternal and fetal outcome in women with antiphospholipid syndrome: a three-year observational study
    • Rezk, M., Dawood, R., Badr, H., Maternal and fetal outcome in women with antiphospholipid syndrome: a three-year observational study. J. Matern. Fetal Neonatal Med. 29 (2016), 4015–4019.
    • (2016) J. Matern. Fetal Neonatal Med. , vol.29 , pp. 4015-4019
    • Rezk, M.1    Dawood, R.2    Badr, H.3
  • 105
    • 84863197776 scopus 로고    scopus 로고
    • Prediction of adverse pregnancy outcome by the presence of lupus anticoagulant, but not anticardiolipin antibody, in patients with antiphospholipid antibodies
    • Lockshin, M.D., Kim, M., Laskin, C.A., Guerra, M., Branch, D.W., Merrill, J., et al. Prediction of adverse pregnancy outcome by the presence of lupus anticoagulant, but not anticardiolipin antibody, in patients with antiphospholipid antibodies. Arthritis Rheum. 64 (2012), 2311–2318.
    • (2012) Arthritis Rheum. , vol.64 , pp. 2311-2318
    • Lockshin, M.D.1    Kim, M.2    Laskin, C.A.3    Guerra, M.4    Branch, D.W.5    Merrill, J.6
  • 107
    • 79958045457 scopus 로고    scopus 로고
    • The association between antiphospholipid antibodies and placenta mediated complications: a systematic review and meta-analysis
    • Abou-Nassar, K., Carrier, M., Ramsay, T., Rodger, M.A., The association between antiphospholipid antibodies and placenta mediated complications: a systematic review and meta-analysis. Thromb. Res. 128 (2011), 77–85.
    • (2011) Thromb. Res. , vol.128 , pp. 77-85
    • Abou-Nassar, K.1    Carrier, M.2    Ramsay, T.3    Rodger, M.A.4
  • 108
    • 84924366763 scopus 로고    scopus 로고
    • Clinical features and pregnancy outcome in antiphospholipid syndrome patients with history of severe pregnancy complications
    • Matsuki, Y., Atsumi, T., Yamaguchi, K., Hisano, M., Arata, N., Oku, K., et al. Clinical features and pregnancy outcome in antiphospholipid syndrome patients with history of severe pregnancy complications. Mod. Rheumatol. 25 (2015), 215–218.
    • (2015) Mod. Rheumatol. , vol.25 , pp. 215-218
    • Matsuki, Y.1    Atsumi, T.2    Yamaguchi, K.3    Hisano, M.4    Arata, N.5    Oku, K.6
  • 109
    • 84937823546 scopus 로고    scopus 로고
    • The association between antiphospholipid antibodies and pregnancy morbidity, stroke, myocardial infarction, and deep vein thrombosis: a critical review of the literature
    • Chighizola, C.B., Andreoli, L., de Jesus, G.R., Banzato, A., Pons-Estel, G.J., Erkan, D., et al. The association between antiphospholipid antibodies and pregnancy morbidity, stroke, myocardial infarction, and deep vein thrombosis: a critical review of the literature. Lupus 24 (2015), 980–984.
    • (2015) Lupus , vol.24 , pp. 980-984
    • Chighizola, C.B.1    Andreoli, L.2    de Jesus, G.R.3    Banzato, A.4    Pons-Estel, G.J.5    Erkan, D.6
  • 110
    • 85015780849 scopus 로고    scopus 로고
    • PREGNANTS (PREGNancy in women with ANTiphospholipid Syndrome) working group. Antiphospholipid antibody profile based obstetric outcomes of primary antiphospholipid syndrome: the PREGNANTS study
    • e1–525.e12
    • Saccone, G., Berghella, V., Maruotti, G.M., Ghi, T., Rizzo, G., Simonazzi, G., et al. PREGNANTS (PREGNancy in women with ANTiphospholipid Syndrome) working group. Antiphospholipid antibody profile based obstetric outcomes of primary antiphospholipid syndrome: the PREGNANTS study. Am. J. Obstet. Gynecol., 216, 2017 e1–525.e12.
    • (2017) Am. J. Obstet. Gynecol. , vol.216
    • Saccone, G.1    Berghella, V.2    Maruotti, G.M.3    Ghi, T.4    Rizzo, G.5    Simonazzi, G.6
  • 111
    • 0037370733 scopus 로고    scopus 로고
    • Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: a systematic review of the literature
    • Galli, M., Luciani, D., Bertolini, G., Barbui, T., Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: a systematic review of the literature. Blood 101 (2003), 1827–1832.
    • (2003) Blood , vol.101 , pp. 1827-1832
    • Galli, M.1    Luciani, D.2    Bertolini, G.3    Barbui, T.4
  • 112
    • 84947284973 scopus 로고    scopus 로고
    • Determination of clinically significant tests for antiphospholipid antibodies and cutoff levels for obstetric antiphospholipid syndrome
    • Kitaori, T., Sugiura-Ogasawara, M., Oku, K., Papisch, W., Ebara, T., Ozaki, Y., et al. Determination of clinically significant tests for antiphospholipid antibodies and cutoff levels for obstetric antiphospholipid syndrome. Lupus 24 (2015), 1505–1519.
    • (2015) Lupus , vol.24 , pp. 1505-1519
    • Kitaori, T.1    Sugiura-Ogasawara, M.2    Oku, K.3    Papisch, W.4    Ebara, T.5    Ozaki, Y.6
  • 114
    • 85019105721 scopus 로고    scopus 로고
    • Antiphosphatidylserine/prothrombin antibodies as biomarkers to identify severe primary antiphospholipid syndrome
    • Hoxha, A., Mattia, E., Tonello, M., Grava, C., Pengo, V., Ruffatti, A., Antiphosphatidylserine/prothrombin antibodies as biomarkers to identify severe primary antiphospholipid syndrome. Clin. Chem. Lab. Med. 55 (2017), 890–898.
    • (2017) Clin. Chem. Lab. Med. , vol.55 , pp. 890-898
    • Hoxha, A.1    Mattia, E.2    Tonello, M.3    Grava, C.4    Pengo, V.5    Ruffatti, A.6
  • 116
    • 84870319871 scopus 로고    scopus 로고
    • Primary anti-phospholipid syndrome: any role for serum complement levels in predicting pregnancy complications?
    • Reggia, R., Ziglioli, T., Andreoli, L., Bellisai, F., Iuliano, A., Gerosa, M., et al. Primary anti-phospholipid syndrome: any role for serum complement levels in predicting pregnancy complications?. Rheumatology 51 (2012), 2186–2190.
    • (2012) Rheumatology , vol.51 , pp. 2186-2190
    • Reggia, R.1    Ziglioli, T.2    Andreoli, L.3    Bellisai, F.4    Iuliano, A.5    Gerosa, M.6
  • 117
    • 74849134126 scopus 로고    scopus 로고
    • Pregnancy outcome in different clinical phenotypes of antiphospholipid syndrome
    • Bramham, K., Hunt, B.J., Germain, S., Calatayud, I., Khamashta, M., Bewley, S., et al. Pregnancy outcome in different clinical phenotypes of antiphospholipid syndrome. Lupus 19 (2010), 58–64.
    • (2010) Lupus , vol.19 , pp. 58-64
    • Bramham, K.1    Hunt, B.J.2    Germain, S.3    Calatayud, I.4    Khamashta, M.5    Bewley, S.6
  • 118
    • 84873162417 scopus 로고    scopus 로고
    • Pregnancy outcome in patients with antiphospholipid syndrome after cerebral ischaemic events: an observational study
    • Fischer-Betz, R., Specker, C., Brinks, S., Schneider, M., Pregnancy outcome in patients with antiphospholipid syndrome after cerebral ischaemic events: an observational study. Lupus 21 (2012), 1183–1189.
    • (2012) Lupus , vol.21 , pp. 1183-1189
    • Fischer-Betz, R.1    Specker, C.2    Brinks, S.3    Schneider, M.4
  • 120
    • 0034810266 scopus 로고    scopus 로고
    • Risk factors associated with fetal losses in treated antiphospholipid syndrome pregnancies: a multivariate analysis
    • Carmona, F., Font, J., Azulay, M., Creus, M., Fábregues, F., Cervera, R., et al. Risk factors associated with fetal losses in treated antiphospholipid syndrome pregnancies: a multivariate analysis. Am. J. Reprod. Immunol. 46 (2001), 274–279.
    • (2001) Am. J. Reprod. Immunol. , vol.46 , pp. 274-279
    • Carmona, F.1    Font, J.2    Azulay, M.3    Creus, M.4    Fábregues, F.5    Cervera, R.6
  • 121
    • 0027144129 scopus 로고
    • Comparative trial of prednisone plus aspirin versus aspirin alone in the treatment of anticardiolipin antibody-positive obstetric patients
    • Silver, R.K., MacGregor, S.N., Sholl, J.S., Hobart, J.M., Neerhof, M.G., Ragin, A., Comparative trial of prednisone plus aspirin versus aspirin alone in the treatment of anticardiolipin antibody-positive obstetric patients. Am. J. Obstet. Gynecol. 169 (1993), 1411–1417.
    • (1993) Am. J. Obstet. Gynecol. , vol.169 , pp. 1411-1417
    • Silver, R.K.1    MacGregor, S.N.2    Sholl, J.S.3    Hobart, J.M.4    Neerhof, M.G.5    Ragin, A.6
  • 123
    • 0030852373 scopus 로고    scopus 로고
    • Obstetric outcome in antiphospholipid syndrome
    • Granger, K.A., Farquharson, R.G., Obstetric outcome in antiphospholipid syndrome. Lupus, 1997, 509–513.
    • (1997) Lupus , pp. 509-513
    • Granger, K.A.1    Farquharson, R.G.2
  • 126
    • 0030881273 scopus 로고    scopus 로고
    • Low-dose aspirin in prevention of miscarriage in women with unexplained or autoimmune related recurrent miscarriage: effect on prostacyclin and thromboxane A2 production
    • Tulppala, M., Marttunen, M., Söderstrom-Anttila, V., Foudila, T., Ailus, K., Palosuo, T., et al. Low-dose aspirin in prevention of miscarriage in women with unexplained or autoimmune related recurrent miscarriage: effect on prostacyclin and thromboxane A2 production. Hum. Reprod. 12 (1997), 1567–1572.
    • (1997) Hum. Reprod. , vol.12 , pp. 1567-1572
    • Tulppala, M.1    Marttunen, M.2    Söderstrom-Anttila, V.3    Foudila, T.4    Ailus, K.5    Palosuo, T.6
  • 127
    • 0033784643 scopus 로고    scopus 로고
    • Does aspirin have a role in improving pregnancy outcome for women with the antiphospholipid syndrome? A randomized controlled trial
    • Pattison, N.S., Chamley, L.W., Birdsall, M., Zanderigo, A.M., Liddell, H.S., McDougall, J., Does aspirin have a role in improving pregnancy outcome for women with the antiphospholipid syndrome? A randomized controlled trial. Am. J. Obstet. Gynecol. 183 (2000), 1008–1012.
    • (2000) Am. J. Obstet. Gynecol. , vol.183 , pp. 1008-1012
    • Pattison, N.S.1    Chamley, L.W.2    Birdsall, M.3    Zanderigo, A.M.4    Liddell, H.S.5    McDougall, J.6
  • 128
    • 0025275902 scopus 로고
    • Heparin therapy for pregnant women with lupus anticoagulant or anticardiolipin antibodies
    • Rosove, M.H., Tabsh, K., Wasserstrum, N., Howard, P., Hahn, B.H., Kalunian, K.C., Heparin therapy for pregnant women with lupus anticoagulant or anticardiolipin antibodies. Obstet. Gynecol. 75 (1990), 630–634.
    • (1990) Obstet. Gynecol. , vol.75 , pp. 630-634
    • Rosove, M.H.1    Tabsh, K.2    Wasserstrum, N.3    Howard, P.4    Hahn, B.H.5    Kalunian, K.C.6
  • 130
    • 12844250084 scopus 로고    scopus 로고
    • Heparin and aspirin attenuate placental apoptosis in vitro: implications for early pregnancy failure
    • Bose, P., Black, S., Kadyrov, M., Weissenborn, U., Neulen, J., Regan, L., et al. Heparin and aspirin attenuate placental apoptosis in vitro: implications for early pregnancy failure. Am. J. Obstet. Gynecol. 192 (2005), 23–30.
    • (2005) Am. J. Obstet. Gynecol. , vol.192 , pp. 23-30
    • Bose, P.1    Black, S.2    Kadyrov, M.3    Weissenborn, U.4    Neulen, J.5    Regan, L.6
  • 131
    • 84922825148 scopus 로고    scopus 로고
    • Aspirin-triggered lipoxin prevents antiphospholipid antibody effects on human trophoblast migration and endothelial cell interactions
    • Alvarez, A.M., Mulla, M.J., Chamley, L.W., Cadavid, A.P., Abrahams, V.M., Aspirin-triggered lipoxin prevents antiphospholipid antibody effects on human trophoblast migration and endothelial cell interactions. Arthritis Rheum. 67 (2015), 488–497.
    • (2015) Arthritis Rheum. , vol.67 , pp. 488-497
    • Alvarez, A.M.1    Mulla, M.J.2    Chamley, L.W.3    Cadavid, A.P.4    Abrahams, V.M.5
  • 132
    • 33847253520 scopus 로고    scopus 로고
    • Pathogenic role of anti-beta2-glycoprotein I antibodies on human placenta: functional effects related to implantation and roles of heparin
    • Di Simone, N., Meroni, P.L., D'Asta, M., Di Nicuolo, F., D'Alessio, M.C., Caruso, A., Pathogenic role of anti-beta2-glycoprotein I antibodies on human placenta: functional effects related to implantation and roles of heparin. Hum. Reprod. Update 13 (2007), 189–196.
    • (2007) Hum. Reprod. Update , vol.13 , pp. 189-196
    • Di Simone, N.1    Meroni, P.L.2    D'Asta, M.3    Di Nicuolo, F.4    D'Alessio, M.C.5    Caruso, A.6
  • 133
    • 84922623040 scopus 로고    scopus 로고
    • Obstetric antiphospholipid syndrome: a recent classification for an old defined disorder
    • D'Ippolito, S., Meroni, P.L., Koike, T., Veglia, M., Scambia, G., Di Simone, N., Obstetric antiphospholipid syndrome: a recent classification for an old defined disorder. Autoimmun. Rev. 13 (2014), 901–908.
    • (2014) Autoimmun. Rev. , vol.13 , pp. 901-908
    • D'Ippolito, S.1    Meroni, P.L.2    Koike, T.3    Veglia, M.4    Scambia, G.5    Di Simone, N.6
  • 134
    • 84855297285 scopus 로고    scopus 로고
    • Effect of low molecular weight heparins (LMWHs) on antiphospholipid antibodies (aPL)-mediated inhibition of endometrial angiogenesis
    • D'Ippolito, S., Marana, R., Di Nicuolo, F., Castellani, R., Veglia, M., Stinson, J., et al. Effect of low molecular weight heparins (LMWHs) on antiphospholipid antibodies (aPL)-mediated inhibition of endometrial angiogenesis. PLoS One, 7, 2012, e29660.
    • (2012) PLoS One , vol.7
    • D'Ippolito, S.1    Marana, R.2    Di Nicuolo, F.3    Castellani, R.4    Veglia, M.5    Stinson, J.6
  • 135
    • 0037169563 scopus 로고    scopus 로고
    • Heparin inhibits the binding of beta 2-glycoprotein I to phospholipids and promotes the plasmin-mediated inactivation of this blood protein. Elucidation of the consequences of the two biological events in patients with the anti-phospholipid syndrome
    • Guerin, J., Sheng, Y., Reddel, S., Iverson, G.M., Chapman, M.G., Krilis, S.A., Heparin inhibits the binding of beta 2-glycoprotein I to phospholipids and promotes the plasmin-mediated inactivation of this blood protein. Elucidation of the consequences of the two biological events in patients with the anti-phospholipid syndrome. J. Biol. Chem. 277 (2002), 2644–2649.
    • (2002) J. Biol. Chem. , vol.277 , pp. 2644-2649
    • Guerin, J.1    Sheng, Y.2    Reddel, S.3    Iverson, G.M.4    Chapman, M.G.5    Krilis, S.A.6
  • 136
    • 9144243607 scopus 로고    scopus 로고
    • Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation
    • Girardi, G., Redecha, P., Salmon, J.E., Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation. Nat. Med. 10 (2004), 1222–12226.
    • (2004) Nat. Med. , vol.10 , pp. 1222-12226
    • Girardi, G.1    Redecha, P.2    Salmon, J.E.3
  • 138
    • 85018972413 scopus 로고    scopus 로고
    • Obstetric antiphospholipid syndrome: early variations of angiogenic factors are associated with adverse outcomes
    • Cochery-Nouvellon, E., Mercier, E., Bouvier, S., Balducchi, J.-P., Quéré I., Perez-Martin, A., et al. Obstetric antiphospholipid syndrome: early variations of angiogenic factors are associated with adverse outcomes. Haematologica 102 (2017), 835–842.
    • (2017) Haematologica , vol.102 , pp. 835-842
    • Cochery-Nouvellon, E.1    Mercier, E.2    Bouvier, S.3    Balducchi, J.-P.4    Quéré, I.5    Perez-Martin, A.6
  • 139
    • 85046597110 scopus 로고    scopus 로고
    • Therapy for antiphospholipid miscarriages: throwing the baby out with the bathwater?
    • Chighizola, C.B., Shoenfeld, Y., Meroni, P.L., Therapy for antiphospholipid miscarriages: throwing the baby out with the bathwater?. Am. J. Reprod. Immunol., 27, 2017, e12792.
    • (2017) Am. J. Reprod. Immunol. , vol.27
    • Chighizola, C.B.1    Shoenfeld, Y.2    Meroni, P.L.3
  • 140
    • 84979642523 scopus 로고    scopus 로고
    • EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome
    • Andreoli, L., Bertsias, G.K., Agmon-Levin, N., Brown, S., Cervera, R., Costedoat-Chalumeau, N., et al. EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome. Ann. Rheum. Dis. 76 (2017), 476–485.
    • (2017) Ann. Rheum. Dis. , vol.76 , pp. 476-485
    • Andreoli, L.1    Bertsias, G.K.2    Agmon-Levin, N.3    Brown, S.4    Cervera, R.5    Costedoat-Chalumeau, N.6
  • 141
    • 45949094478 scopus 로고    scopus 로고
    • Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of chest physicians evidence-based clinical practice guidelines (8th edition)
    • Bates, S.M., Greer, J.A., Pabinger, I., Sofaer, S., Hirsh, J., Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of chest physicians evidence-based clinical practice guidelines (8th edition). Chest 133 (2008), 844S–886S.
    • (2008) Chest , vol.133 , pp. 844S-886S
    • Bates, S.M.1    Greer, J.A.2    Pabinger, I.3    Sofaer, S.4    Hirsh, J.5
  • 142
    • 84858283382 scopus 로고    scopus 로고
    • British Committee for Standards in Haematology. Guidelines on the investigation and management of antiphospholipid syndrome
    • Keeling, D., Mackie, I., Moore, G.W., Greer, I.A., Greaves, M., British Committee for Standards in Haematology. Guidelines on the investigation and management of antiphospholipid syndrome. Br. J. Haematol. 157 (2012), 47–58.
    • (2012) Br. J. Haematol. , vol.157 , pp. 47-58
    • Keeling, D.1    Mackie, I.2    Moore, G.W.3    Greer, I.A.4    Greaves, M.5
  • 143
    • 84940702545 scopus 로고    scopus 로고
    • Limited evidence for diagnosing and treating “non-criteria obstetric antiphospholipid syndrome”
    • Ramires de Jesús, G., Levy, R.A., Porter, T.F., Branch, D.W., Limited evidence for diagnosing and treating “non-criteria obstetric antiphospholipid syndrome”. Thromb. Haemostasis 114 (2015), 651–652.
    • (2015) Thromb. Haemostasis , vol.114 , pp. 651-652
    • Ramires de Jesús, G.1    Levy, R.A.2    Porter, T.F.3    Branch, D.W.4
  • 144
    • 77950377251 scopus 로고    scopus 로고
    • Combination of heparin and aspirin is superior to aspirin alone in enhancing live births in patients with recurrent pregnancy loss and positive anti-phospholipid antibodies: a meta-analysis of randomized controlled trials and meta-regression
    • Mak, A., Cheung, M.W.-L., Cheak, A.A.-C., Ho, R.C.-O., Combination of heparin and aspirin is superior to aspirin alone in enhancing live births in patients with recurrent pregnancy loss and positive anti-phospholipid antibodies: a meta-analysis of randomized controlled trials and meta-regression. Rheumatology 49 (2010), 281–288.
    • (2010) Rheumatology , vol.49 , pp. 281-288
    • Mak, A.1    Cheung, M.W.-L.2    Cheak, A.A.-C.3    Ho, R.C.-O.4
  • 145
    • 77952981639 scopus 로고    scopus 로고
    • Heparin treatment in antiphospholipid syndrome with recurrent pregnancy loss: a systematic review and meta-analysis
    • Ziakas, P.D., Pavlou, M., Voulgarelis, M., Heparin treatment in antiphospholipid syndrome with recurrent pregnancy loss: a systematic review and meta-analysis. Obstet. Gynecol. 115 (2010), 1256–1262.
    • (2010) Obstet. Gynecol. , vol.115 , pp. 1256-1262
    • Ziakas, P.D.1    Pavlou, M.2    Voulgarelis, M.3
  • 146
    • 84921705962 scopus 로고    scopus 로고
    • Prevention of recurrent miscarriage for women with antiphospholipid antibody or lupus anticoagulant
    • Empson, M., Lassere, M., Craig, J., Scott, J., Prevention of recurrent miscarriage for women with antiphospholipid antibody or lupus anticoagulant. Cochrane Database Syst. Rev., 182, 2005, CD002859.
    • (2005) Cochrane Database Syst. Rev. , vol.182
    • Empson, M.1    Lassere, M.2    Craig, J.3    Scott, J.4
  • 147
    • 84920177987 scopus 로고    scopus 로고
    • Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia
    • de Jong, P.G., Kaandorp, S., Di Nisio, M., Goddijn, M., Middeldorp, S., Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia. Cochrane Database Syst. Rev., 7, 2014, CD004734.
    • (2014) Cochrane Database Syst. Rev. , vol.7
    • de Jong, P.G.1    Kaandorp, S.2    Di Nisio, M.3    Goddijn, M.4    Middeldorp, S.5
  • 148
    • 84864278628 scopus 로고    scopus 로고
    • Early administration of low-dose aspirin for the prevention of severe and mild preeclampsia: a systematic review and meta-analysis
    • Roberge, R., Giguère, Y., Villa, P., Nicolaides, K., Vainio, M., Forest, J.-C., et al. Early administration of low-dose aspirin for the prevention of severe and mild preeclampsia: a systematic review and meta-analysis. Am. J. Perinatol. 29 (2012), 551–556.
    • (2012) Am. J. Perinatol. , vol.29 , pp. 551-556
    • Roberge, R.1    Giguère, Y.2    Villa, P.3    Nicolaides, K.4    Vainio, M.5    Forest, J.-C.6
  • 149
    • 77955147909 scopus 로고    scopus 로고
    • Prevention of preeclampsia and intrauterine growth restriction with aspirin started in early pregnancy: a meta-analysis
    • Bujold, E., Roberge, S., Lacasse, Y., Bureau, M., Audibert, F., Marcoux, S., et al. Prevention of preeclampsia and intrauterine growth restriction with aspirin started in early pregnancy: a meta-analysis. Obstet. Gynecol. 116 (2010), 402–414.
    • (2010) Obstet. Gynecol. , vol.116 , pp. 402-414
    • Bujold, E.1    Roberge, S.2    Lacasse, Y.3    Bureau, M.4    Audibert, F.5    Marcoux, S.6
  • 150
    • 84894025152 scopus 로고    scopus 로고
    • Meta-analysis of low-molecular-weight heparin to prevent recurrent placenta-mediated pregnancy complications
    • Rodger, M.A., Carrier, M., Le Gal, G., Martinelli, I., Perna, A., Rey, E., et al. Meta-analysis of low-molecular-weight heparin to prevent recurrent placenta-mediated pregnancy complications. Blood 123 (2014), 822–828.
    • (2014) Blood , vol.123 , pp. 822-828
    • Rodger, M.A.1    Carrier, M.2    Le Gal, G.3    Martinelli, I.4    Perna, A.5    Rey, E.6
  • 154
  • 155
    • 0035652633 scopus 로고    scopus 로고
    • Low molecular weight heparin and warfarin in the treatment of patients with antiphospholipid syndrome during pregnancy
    • Pauzner, R., Dulitzki, M., Langevitz, P., Livneh, A., Kenett, R., Many, A., Low molecular weight heparin and warfarin in the treatment of patients with antiphospholipid syndrome during pregnancy. Thromb. Haemostasis 86 (2001), 1379–1384.
    • (2001) Thromb. Haemostasis , vol.86 , pp. 1379-1384
    • Pauzner, R.1    Dulitzki, M.2    Langevitz, P.3    Livneh, A.4    Kenett, R.5    Many, A.6
  • 156
  • 157
    • 84978229544 scopus 로고    scopus 로고
    • Inherited thrombophilia in women with poor aPL-related obstetric history: prevalence and outcomes. Survey of 208 cases from the European Registry on Obstetric Antiphospholipid Syndrome cohort
    • Alijotas-Reig, J., Ferrer-Oliveras, R., Esteve-Valverde, E., Ruffatti, A., Tincani, A., Lefkou, E., et al. Inherited thrombophilia in women with poor aPL-related obstetric history: prevalence and outcomes. Survey of 208 cases from the European Registry on Obstetric Antiphospholipid Syndrome cohort. Am. J. Reprod. Immunol. 76 (2016), 164–171.
    • (2016) Am. J. Reprod. Immunol. , vol.76 , pp. 164-171
    • Alijotas-Reig, J.1    Ferrer-Oliveras, R.2    Esteve-Valverde, E.3    Ruffatti, A.4    Tincani, A.5    Lefkou, E.6
  • 158
    • 7944225659 scopus 로고    scopus 로고
    • Treatment of antiphospholipid antibody syndrome (APS) in pregnancy: a randomized pilot trial comparing low molecular weight heparin to unfractionated heparin
    • Stephenson, M.D., Ballem, P.J., Tsang, P., Purkiss, S., Ensworth, S., Houlihan, E., et al. Treatment of antiphospholipid antibody syndrome (APS) in pregnancy: a randomized pilot trial comparing low molecular weight heparin to unfractionated heparin. J. Obstet. Gynaecol. Can. 26 (2004), 729–734.
    • (2004) J. Obstet. Gynaecol. Can. , vol.26 , pp. 729-734
    • Stephenson, M.D.1    Ballem, P.J.2    Tsang, P.3    Purkiss, S.4    Ensworth, S.5    Houlihan, E.6
  • 159
    • 14844286167 scopus 로고    scopus 로고
    • Antiphospholipid antibodies associated with recurrent pregnancy loss: prospective, multicenter, controlled pilot study comparing treatment with low-molecular-weight heparin versus unfractionated heparin
    • Noble, L.S., Kutteh, W.H., Lashey, N., Franklin, R.D., Herrada, J., Antiphospholipid antibodies associated with recurrent pregnancy loss: prospective, multicenter, controlled pilot study comparing treatment with low-molecular-weight heparin versus unfractionated heparin. Fertil. Steril. 83 (2005), 684–690.
    • (2005) Fertil. Steril. , vol.83 , pp. 684-690
    • Noble, L.S.1    Kutteh, W.H.2    Lashey, N.3    Franklin, R.D.4    Herrada, J.5
  • 160
    • 79951673294 scopus 로고    scopus 로고
    • Enoxaparin versus unfractionated heparin in the management of recurrent abortion secondary to antiphospholipid syndrome
    • Fouda, U.M., Sayed, A.M., Abdou, A.-M.A., Ramadan, D.I., Fouda, I.M., Zaki, M.M., Enoxaparin versus unfractionated heparin in the management of recurrent abortion secondary to antiphospholipid syndrome. Int. J. Gynaecol. Obstet. 112 (2011), 211–215.
    • (2011) Int. J. Gynaecol. Obstet. , vol.112 , pp. 211-215
    • Fouda, U.M.1    Sayed, A.M.2    Abdou, A.-M.A.3    Ramadan, D.I.4    Fouda, I.M.5    Zaki, M.M.6
  • 161
    • 84893113042 scopus 로고    scopus 로고
    • Vitamin D deficiency may be a risk factor for recurrent pregnancy losses by increasing cellular immunity and autoimmunity
    • Ota, K., Dambaeva, S., Han, A.-R., Beaman, K., Gilman-Sachs, A., Kwak-Kim, J., Vitamin D deficiency may be a risk factor for recurrent pregnancy losses by increasing cellular immunity and autoimmunity. Hum. Reprod. 29 (2014), 208–219.
    • (2014) Hum. Reprod. , vol.29 , pp. 208-219
    • Ota, K.1    Dambaeva, S.2    Han, A.-R.3    Beaman, K.4    Gilman-Sachs, A.5    Kwak-Kim, J.6
  • 163
    • 80052054220 scopus 로고    scopus 로고
    • Adjusted prophylactic doses of nadroparin plus low dose aspirin therapy in obstetric antiphospholipid syndrome. A prospective cohort management study
    • Ruffatti, A., Gervasi, M.T., Favaro, M., Ruffatti, A.T., Hoxha, A., Punzi, L., Adjusted prophylactic doses of nadroparin plus low dose aspirin therapy in obstetric antiphospholipid syndrome. A prospective cohort management study. Clin. Exp. Rheumatol. 29 (2011), 551–554.
    • (2011) Clin. Exp. Rheumatol. , vol.29 , pp. 551-554
    • Ruffatti, A.1    Gervasi, M.T.2    Favaro, M.3    Ruffatti, A.T.4    Hoxha, A.5    Punzi, L.6
  • 164
    • 77954513283 scopus 로고    scopus 로고
    • Should bilateral uterine artery notching be used in the risk assessment for preeclampsia, small-for-gestational-age, and gestational hypertension?
    • Espinoza, J., Kusanovic, J.P., Bahado-Singh, R., Gervasi, M.T., Romero, R., Lee, W., et al. Should bilateral uterine artery notching be used in the risk assessment for preeclampsia, small-for-gestational-age, and gestational hypertension?. J. Ultrasound Med. 29 (2010), 1103–1115.
    • (2010) J. Ultrasound Med. , vol.29 , pp. 1103-1115
    • Espinoza, J.1    Kusanovic, J.P.2    Bahado-Singh, R.3    Gervasi, M.T.4    Romero, R.5    Lee, W.6
  • 165
    • 74549191939 scopus 로고    scopus 로고
    • Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American society of regional anesthesia and pain medicine evidence-based guidelines (third edition)
    • Horlocker, T.T., Wedel, D.J., Rowlingson, J.C., Enneking, F.K., Kopp, S.L., Benzon, H.T., et al. Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American society of regional anesthesia and pain medicine evidence-based guidelines (third edition). Reg. Anesth. Pain Med. 35 (2010), 64–101.
    • (2010) Reg. Anesth. Pain Med. , vol.35 , pp. 64-101
    • Horlocker, T.T.1    Wedel, D.J.2    Rowlingson, J.C.3    Enneking, F.K.4    Kopp, S.L.5    Benzon, H.T.6
  • 167
    • 57949106754 scopus 로고    scopus 로고
    • Laboratory classification categories and pregnancy outcome in patients with primary antiphospholipid syndrome prescribed antithrombotic therapy
    • Ruffatti, A., Tonello, M., Cavazzana, A., Bagatella, P., Pengo, V., Laboratory classification categories and pregnancy outcome in patients with primary antiphospholipid syndrome prescribed antithrombotic therapy. Thromb. Res. 123 (2009), 482–487.
    • (2009) Thromb. Res. , vol.123 , pp. 482-487
    • Ruffatti, A.1    Tonello, M.2    Cavazzana, A.3    Bagatella, P.4    Pengo, V.5
  • 168
    • 84893089265 scopus 로고    scopus 로고
    • Comparative incidence of pregnancy outcomes in treated obstetric antiphospholipid syndrome: the NOH-APS observational study
    • Bouvier, S., Cochery-Nouvellon, E., Lavigne-Lissalde, G., Mercier, E., Marchetti, T., Balducchi, J.-P., et al. Comparative incidence of pregnancy outcomes in treated obstetric antiphospholipid syndrome: the NOH-APS observational study. Blood 123 (2014), 404–413.
    • (2014) Blood , vol.123 , pp. 404-413
    • Bouvier, S.1    Cochery-Nouvellon, E.2    Lavigne-Lissalde, G.3    Mercier, E.4    Marchetti, T.5    Balducchi, J.-P.6
  • 170
    • 54549099356 scopus 로고    scopus 로고
    • Management of the controversial aspects of the antiphospholipid syndrome pregnancies: a guide for clinicians and researchers
    • iii23–27
    • Erkan, D., Patel, S., Nuzzo, M., Gerosa, M., Meroni, P.L., Tincani, A., Lockshin, M.D., Management of the controversial aspects of the antiphospholipid syndrome pregnancies: a guide for clinicians and researchers. Rheumatology, 47, 2008 iii23–27.
    • (2008) Rheumatology , vol.47
    • Erkan, D.1    Patel, S.2    Nuzzo, M.3    Gerosa, M.4    Meroni, P.L.5    Tincani, A.6    Lockshin, M.D.7
  • 171
    • 0020640457 scopus 로고
    • Fetal survival after prednisone suppression of maternal lupus-anticoagulant
    • Lubbe, W.F., Butler, W.S., Palmer, S.J., Liggins, G.C., Fetal survival after prednisone suppression of maternal lupus-anticoagulant. Lancet 1 (1983), 1361–1363.
    • (1983) Lancet , vol.1 , pp. 1361-1363
    • Lubbe, W.F.1    Butler, W.S.2    Palmer, S.J.3    Liggins, G.C.4
  • 172
    • 0024578482 scopus 로고
    • Prednisone does not prevent recurrent fetal death in women with antiphospholipid antibody
    • Lockshin, M.D., Druzin, M.L., Qamar, T., Prednisone does not prevent recurrent fetal death in women with antiphospholipid antibody. Am. J. Obstet. Gynecol. 160 (1989), 439–443.
    • (1989) Am. J. Obstet. Gynecol. , vol.160 , pp. 439-443
    • Lockshin, M.D.1    Druzin, M.L.2    Qamar, T.3
  • 173
    • 79959504067 scopus 로고    scopus 로고
    • First-trimester low-dose prednisolone in refractory antiphospholipid antibody-related pregnancy loss
    • Bramham, K., Thomas, M., Nelson-Piercy, C., Khamashta, M., Hunt, B.J., First-trimester low-dose prednisolone in refractory antiphospholipid antibody-related pregnancy loss. Blood 117 (2011), 6948–6951.
    • (2011) Blood , vol.117 , pp. 6948-6951
    • Bramham, K.1    Thomas, M.2    Nelson-Piercy, C.3    Khamashta, M.4    Hunt, B.J.5
  • 174
    • 85019168322 scopus 로고    scopus 로고
    • Refractory obstetrical antiphospholipid syndrome: features, treatment and outcome in a European multicenter retrospective study
    • Mekinian, A., Alijotas-Reig, J., Carrat, F., Costedoat-Chalumeau, N., Ruffatti, A., Lazzaroni, M.G., et al. Refractory obstetrical antiphospholipid syndrome: features, treatment and outcome in a European multicenter retrospective study. Autoimmun. Rev. 16 (2017), 730–734.
    • (2017) Autoimmun. Rev. , vol.16 , pp. 730-734
    • Mekinian, A.1    Alijotas-Reig, J.2    Carrat, F.3    Costedoat-Chalumeau, N.4    Ruffatti, A.5    Lazzaroni, M.G.6
  • 175
  • 176
    • 81855167427 scopus 로고    scopus 로고
    • Hydroxychloroquine reduces binding of antiphospholipid antibodies to syncytiotrophoblasts and restores annexin A5 expression
    • 576.e7–14
    • Wu, X.-X., Guller, S., Rand, J.H., Hydroxychloroquine reduces binding of antiphospholipid antibodies to syncytiotrophoblasts and restores annexin A5 expression. Am. J. Obstet. Gynecol., 205, 2011 576.e7–14.
    • (2011) Am. J. Obstet. Gynecol. , vol.205
    • Wu, X.-X.1    Guller, S.2    Rand, J.H.3
  • 177
    • 84892438423 scopus 로고    scopus 로고
    • Effect of hydroxychloroquine on antiphospholipid antibody-induced changes in first trimester trophoblast function
    • Albert, C.R., Schlesinger, W.J., Viall, C.A., Mulla, M.J., Brosens, J.J., Chamley, L.W., et al. Effect of hydroxychloroquine on antiphospholipid antibody-induced changes in first trimester trophoblast function. Am. J. Reprod. Immunol. 71 (2013), 154–164.
    • (2013) Am. J. Reprod. Immunol. , vol.71 , pp. 154-164
    • Albert, C.R.1    Schlesinger, W.J.2    Viall, C.A.3    Mulla, M.J.4    Brosens, J.J.5    Chamley, L.W.6
  • 178
    • 84965056655 scopus 로고    scopus 로고
    • Complement inhibition by hydroxychloroquine prevents placental and fetal brain abnormalities in antiphospholipid syndrome
    • Bertolaccini, M.L., Contento, G., Lennen, R., Sanna, G., Blower, P.J., Ma, M.T., et al. Complement inhibition by hydroxychloroquine prevents placental and fetal brain abnormalities in antiphospholipid syndrome. J. Autoimmun. 75 (2016), 30–38.
    • (2016) J. Autoimmun. , vol.75 , pp. 30-38
    • Bertolaccini, M.L.1    Contento, G.2    Lennen, R.3    Sanna, G.4    Blower, P.J.5    Ma, M.T.6
  • 179
    • 0023820822 scopus 로고
    • Antimalarial drugs and pregnancy
    • Parke, A., Antimalarial drugs and pregnancy. Am. J. Med. 85 (1988), 30–33.
    • (1988) Am. J. Med. , vol.85 , pp. 30-33
    • Parke, A.1
  • 180
    • 84933670410 scopus 로고    scopus 로고
    • The efficacy of hydroxychloroquine for obstetrical outcome in anti-phospholipid syndrome: data from a European multicenter retrospective study
    • Mekinian, A., Lazzaroni, M.G., Kuzenko, A., Alijotas-Reig, J., Ruffatti, A., Levy, P., et al. The efficacy of hydroxychloroquine for obstetrical outcome in anti-phospholipid syndrome: data from a European multicenter retrospective study. Autoimmun. Rev. 14 (2015), 498–502.
    • (2015) Autoimmun. Rev. , vol.14 , pp. 498-502
    • Mekinian, A.1    Lazzaroni, M.G.2    Kuzenko, A.3    Alijotas-Reig, J.4    Ruffatti, A.5    Levy, P.6
  • 181
    • 84957565813 scopus 로고    scopus 로고
    • The efficacy of hydroxychloroquine in altering pregnancy outcome in women with antiphospholipid antibodies. Evidence and clinical judgment
    • Sciascia, S., Branch, D.W., Levy, R.A., Middeldorp, S., Pavord, S., Roccatello, D., et al. The efficacy of hydroxychloroquine in altering pregnancy outcome in women with antiphospholipid antibodies. Evidence and clinical judgment. Thromb. Haemostasis 115 (2016), 285–290.
    • (2016) Thromb. Haemostasis , vol.115 , pp. 285-290
    • Sciascia, S.1    Branch, D.W.2    Levy, R.A.3    Middeldorp, S.4    Pavord, S.5    Roccatello, D.6
  • 182
    • 85020704652 scopus 로고    scopus 로고
    • Hydroxychloroquine to improve pregnancy outcome in women with antIphospholipid antibodies (HYPATIA) protocol: a multinational randomized controlled trial of hydroxychloroquine versus placebo in addition to standard treatment in pregnant women with antiphospholipid syndrome or antibodies
    • Schreiber, K., Breen, K., Cohen, H., Jacobsen, S., Middeldorp, S., Pavord, S., et al. Hydroxychloroquine to improve pregnancy outcome in women with antIphospholipid antibodies (HYPATIA) protocol: a multinational randomized controlled trial of hydroxychloroquine versus placebo in addition to standard treatment in pregnant women with antiphospholipid syndrome or antibodies. Semin. Thromb. Hemost. 43 (2017), 562–571.
    • (2017) Semin. Thromb. Hemost. , vol.43 , pp. 562-571
    • Schreiber, K.1    Breen, K.2    Cohen, H.3    Jacobsen, S.4    Middeldorp, S.5    Pavord, S.6
  • 183
    • 0023713269 scopus 로고
    • Lupus anticoagulant and recurrent fetal loss: successful treatment with gammaglobulin
    • Carreras, L.D., Perez, G.N., Vega, H.R., Casavilla, F., Lupus anticoagulant and recurrent fetal loss: successful treatment with gammaglobulin. Lancet 2 (1988), 393–394.
    • (1988) Lancet , vol.2 , pp. 393-394
    • Carreras, L.D.1    Perez, G.N.2    Vega, H.R.3    Casavilla, F.4
  • 184
    • 0024515466 scopus 로고
    • Intravenous gamma-globulin, antiphospholipid antibodies, and pregnancy
    • Parke, A., Maier, D., Wilson, D., Andreoli, J., Ballow, M., Intravenous gamma-globulin, antiphospholipid antibodies, and pregnancy. Ann. Intern. Med. 110 (1989), 495–496.
    • (1989) Ann. Intern. Med. , vol.110 , pp. 495-496
    • Parke, A.1    Maier, D.2    Wilson, D.3    Andreoli, J.4    Ballow, M.5
  • 185
    • 0024398190 scopus 로고
    • Successful treatment in two women with antiphospholipid antibodies and refractory pregnancy losses with intravenous immunoglobulin infusions
    • Wapner, R.J., Cowchock, F.S., Shapiro, S.S., Successful treatment in two women with antiphospholipid antibodies and refractory pregnancy losses with intravenous immunoglobulin infusions. Am. J. Obstet. Gynecol. 161 (1989), 1271–1272.
    • (1989) Am. J. Obstet. Gynecol. , vol.161 , pp. 1271-1272
    • Wapner, R.J.1    Cowchock, F.S.2    Shapiro, S.S.3
  • 186
    • 0027339619 scopus 로고
    • Intravenous immunoglobulin treatment of pregnant patients with recurrent pregnancy losses associated with antiphospholipid antibodies
    • Kaaja, R., Julkunen, H., Ammälä P., Palosuo, T., Kurki, P., Intravenous immunoglobulin treatment of pregnant patients with recurrent pregnancy losses associated with antiphospholipid antibodies. Acta Obstet. Gynecol. Scand. 72 (1993), 63–66.
    • (1993) Acta Obstet. Gynecol. Scand. , vol.72 , pp. 63-66
    • Kaaja, R.1    Julkunen, H.2    Ammälä, P.3    Palosuo, T.4    Kurki, P.5
  • 187
    • 0028338966 scopus 로고
    • High-dose intravenous immunoglobulin treatment of a pregnant patient with an antiphospholipid syndrome: immunological changes associated with a successful outcome
    • Arnout, J., Spitz, B., Wittevrongel, C., Vanrusselt, M., Van Assche, A., Vermylen, J., High-dose intravenous immunoglobulin treatment of a pregnant patient with an antiphospholipid syndrome: immunological changes associated with a successful outcome. Thromb. Haemostasis 71 (1994), 741–747.
    • (1994) Thromb. Haemostasis , vol.71 , pp. 741-747
    • Arnout, J.1    Spitz, B.2    Wittevrongel, C.3    Vanrusselt, M.4    Van Assche, A.5    Vermylen, J.6
  • 188
    • 0032144490 scopus 로고    scopus 로고
    • Intravenous immunoglobulin therapy in compromised pregnancies associated with antiphospholipid antibodies and systemic lupus erythematosus
    • Somerset, D.A., Raine-Fenning, N., Gordon, C., Weaver, J.B., Kilby, M.D., Intravenous immunoglobulin therapy in compromised pregnancies associated with antiphospholipid antibodies and systemic lupus erythematosus. Eur. J. Obstet. Gynecol. Reprod. Biol. 79 (1998), 227–229.
    • (1998) Eur. J. Obstet. Gynecol. Reprod. Biol. , vol.79 , pp. 227-229
    • Somerset, D.A.1    Raine-Fenning, N.2    Gordon, C.3    Weaver, J.B.4    Kilby, M.D.5
  • 189
    • 0033979270 scopus 로고    scopus 로고
    • A multicenter, placebo-controlled pilot study of intravenous immune globulin treatment of antiphospholipid syndrome during pregnancy. The Pregnancy Loss Study Group
    • Branch, D.W., Peaceman, A.M., Druzin, M., Silver, R.K., El-Sayed, Y., Silver, R.M., et al. A multicenter, placebo-controlled pilot study of intravenous immune globulin treatment of antiphospholipid syndrome during pregnancy. The Pregnancy Loss Study Group. Am. J. Obstet. Gynecol. 181 (2000), 122–127.
    • (2000) Am. J. Obstet. Gynecol. , vol.181 , pp. 122-127
    • Branch, D.W.1    Peaceman, A.M.2    Druzin, M.3    Silver, R.K.4    El-Sayed, Y.5    Silver, R.M.6
  • 190
    • 34547567004 scopus 로고    scopus 로고
    • Treatment of antiphospholipid syndrome in pregnancy with low doses of intravenous immunoglobulin
    • Stojanovich, L., Mikovic, Z., Mandic, V., Popovich-Kuzmanovich, D., Treatment of antiphospholipid syndrome in pregnancy with low doses of intravenous immunoglobulin. Isr. Med. Assoc. J. 9 (2007), 555–556.
    • (2007) Isr. Med. Assoc. J. , vol.9 , pp. 555-556
    • Stojanovich, L.1    Mikovic, Z.2    Mandic, V.3    Popovich-Kuzmanovich, D.4
  • 191
    • 84904763477 scopus 로고    scopus 로고
    • Recurrent thrombosis prevention with intravenous immunoglobulin and hydroxychloroquine during pregnancy in a patient with history of catastrophic antiphospholipid syndrome and pregnancy loss
    • Mar, N., Kosowicz, R., Hook, K., Recurrent thrombosis prevention with intravenous immunoglobulin and hydroxychloroquine during pregnancy in a patient with history of catastrophic antiphospholipid syndrome and pregnancy loss. J. Thromb. Thrombolysis 38 (2014), 196–200.
    • (2014) J. Thromb. Thrombolysis , vol.38 , pp. 196-200
    • Mar, N.1    Kosowicz, R.2    Hook, K.3
  • 193
    • 0026576922 scopus 로고
    • Immunoadsorbent plasmapheresis for a patient with antiphospholipid syndrome during pregnancy
    • Kobayashi, S., Tamura, N., Tsuda, H., Mokuno, C., Hashimoto, H., Hirose, S., Immunoadsorbent plasmapheresis for a patient with antiphospholipid syndrome during pregnancy. Ann. Rheum. Dis. 51 (1992), 399–401.
    • (1992) Ann. Rheum. Dis. , vol.51 , pp. 399-401
    • Kobayashi, S.1    Tamura, N.2    Tsuda, H.3    Mokuno, C.4    Hashimoto, H.5    Hirose, S.6
  • 194
    • 0032986991 scopus 로고    scopus 로고
    • Immunoadsorption plasmapheresis as a treatment for pregnancy complicated by systemic lupus erythematosus with positive antiphospholipid antibodies
    • Nakamura, Y., Yoshida, K., Itoh, S., Kanai, Y., Tsuda, H., Hashimoto, H., et al. Immunoadsorption plasmapheresis as a treatment for pregnancy complicated by systemic lupus erythematosus with positive antiphospholipid antibodies. Am. J. Reprod. Immunol. 41 (1999), 307–311.
    • (1999) Am. J. Reprod. Immunol. , vol.41 , pp. 307-311
    • Nakamura, Y.1    Yoshida, K.2    Itoh, S.3    Kanai, Y.4    Tsuda, H.5    Hashimoto, H.6
  • 195
    • 63349110639 scopus 로고    scopus 로고
    • Case reports of the use of immunoadsorption or plasma exchange in high-risk pregnancies of women with antiphospholipid syndrome
    • Bortolati, M., Marson, P., Chiarelli, S., Tison, T., Facchinetti, M., Gervasi, M.T., et al. Case reports of the use of immunoadsorption or plasma exchange in high-risk pregnancies of women with antiphospholipid syndrome. Ther. Apher. Dial. 13 (2009), 157–160.
    • (2009) Ther. Apher. Dial. , vol.13 , pp. 157-160
    • Bortolati, M.1    Marson, P.2    Chiarelli, S.3    Tison, T.4    Facchinetti, M.5    Gervasi, M.T.6
  • 197
    • 0023226294 scopus 로고
    • Successful removal of anti-phospholipid antibody during pregnancy using plasma exchange and low-dose prednisolone
    • Frampton, G., Cameron, J.S., Thom, M., Jones, S., Raftery, M., Successful removal of anti-phospholipid antibody during pregnancy using plasma exchange and low-dose prednisolone. Lancet 2 (1987), 1023–1024.
    • (1987) Lancet , vol.2 , pp. 1023-1024
    • Frampton, G.1    Cameron, J.S.2    Thom, M.3    Jones, S.4    Raftery, M.5
  • 198
    • 35548952677 scopus 로고    scopus 로고
    • Plasmapheresis and pregnancy outcome in patients with antiphospholipid syndrome
    • El-Haieg, D.O., Zanati, M.F., El-Foual, F.M., Plasmapheresis and pregnancy outcome in patients with antiphospholipid syndrome. Int. J. Gynaecol. Obstet. 99 (2007), 236–241.
    • (2007) Int. J. Gynaecol. Obstet. , vol.99 , pp. 236-241
    • El-Haieg, D.O.1    Zanati, M.F.2    El-Foual, F.M.3
  • 199
    • 33846638644 scopus 로고    scopus 로고
    • Plasma exchange in the management of high risk pregnant patients with primary antiphospholipid syndrome. A report of 9 cases and a review of the literature
    • Ruffatti, A., Marson, P., Pengo, V., Favaro, M., Tonello, M., Bortolati, M., et al. Plasma exchange in the management of high risk pregnant patients with primary antiphospholipid syndrome. A report of 9 cases and a review of the literature. Autoimmun. Rev. 6 (2007), 196–202.
    • (2007) Autoimmun. Rev. , vol.6 , pp. 196-202
    • Ruffatti, A.1    Marson, P.2    Pengo, V.3    Favaro, M.4    Tonello, M.5    Bortolati, M.6
  • 200
    • 84910018535 scopus 로고    scopus 로고
    • Management of very high risk pregnancy with secondary anti-phospholipid syndrome and triple positivity to the anti-phospholipid antibodies
    • Rose, H.L., Ho, W.K., Management of very high risk pregnancy with secondary anti-phospholipid syndrome and triple positivity to the anti-phospholipid antibodies. J. Thromb. Thrombolysis 38 (2014), 453–456.
    • (2014) J. Thromb. Thrombolysis , vol.38 , pp. 453-456
    • Rose, H.L.1    Ho, W.K.2
  • 201
    • 85020577811 scopus 로고    scopus 로고
    • Response to plasmapheresis measured by angiogenic factors in a woman with antiphospholipid syndrome in pregnancy
    • 123408–6
    • Mayer-Pickel, K., Horn, S., Lang, U., Cervar-Zivkovic, M., Response to plasmapheresis measured by angiogenic factors in a woman with antiphospholipid syndrome in pregnancy. Case. Rep. Obstet. Gynecol., 2015, 2015 123408–6.
    • (2015) Case. Rep. Obstet. Gynecol. , vol.2015
    • Mayer-Pickel, K.1    Horn, S.2    Lang, U.3    Cervar-Zivkovic, M.4
  • 202
    • 84962920443 scopus 로고    scopus 로고
    • Apheresis and intravenous immunoglobulins used in addition to conventional therapy to treat high-risk pregnant antiphospholipid antibody syndrome patients. A prospective study
    • Ruffatti, A., Favaro, M., Hoxha, A., Zambon, A., Marson, P., del Ross, T., et al. Apheresis and intravenous immunoglobulins used in addition to conventional therapy to treat high-risk pregnant antiphospholipid antibody syndrome patients. A prospective study. J. Reprod. Immunol. 115 (2016), 14–19.
    • (2016) J. Reprod. Immunol. , vol.115 , pp. 14-19
    • Ruffatti, A.1    Favaro, M.2    Hoxha, A.3    Zambon, A.4    Marson, P.5    del Ross, T.6
  • 203
    • 84908528863 scopus 로고    scopus 로고
    • Treatment strategies and pregnancy outcomes in antiphospholipid syndrome patients with thrombosis and triple antiphospholipid positivity. A European multicentre retrospective study
    • Ruffatti, A., Salvan, E., del Ross, T., Gerosa, M., Andreoli, L., Maina, A., et al. Treatment strategies and pregnancy outcomes in antiphospholipid syndrome patients with thrombosis and triple antiphospholipid positivity. A European multicentre retrospective study. Thromb. Haemostasis 112 (2014), 727–735.
    • (2014) Thromb. Haemostasis , vol.112 , pp. 727-735
    • Ruffatti, A.1    Salvan, E.2    del Ross, T.3    Gerosa, M.4    Andreoli, L.5    Maina, A.6
  • 204
    • 55849112296 scopus 로고    scopus 로고
    • Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome
    • Redecha, P., Franzke, C.W., Ruf, W., Mackman, N., Girardi, G., Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome. J. Clin. Invest. 118 (2008), 3453–3461.
    • (2008) J. Clin. Invest. , vol.118 , pp. 3453-3461
    • Redecha, P.1    Franzke, C.W.2    Ruf, W.3    Mackman, N.4    Girardi, G.5
  • 205
    • 85030858021 scopus 로고    scopus 로고
    • Pravastatin to treat and prevent preeclampsia, Preclinical and clinical studies
    • Girardi, G., Pravastatin to treat and prevent preeclampsia, Preclinical and clinical studies. J. Reprod. Immunol. 124 (2017), 15–20.
    • (2017) J. Reprod. Immunol. , vol.124 , pp. 15-20
    • Girardi, G.1
  • 207
    • 84987837104 scopus 로고    scopus 로고
    • Pravastatin improves pregnancy outcomes in obstetric antipho spholipid syndrome refractory to antithrombotic therapy
    • Lefkou, E., Mamopoulos, A., Dagklis, T., Vosnakis, C., Rousso, D., Girardi, G., Pravastatin improves pregnancy outcomes in obstetric antipho spholipid syndrome refractory to antithrombotic therapy. J. Clin. Invest. 126 (2016), 2933–2940.
    • (2016) J. Clin. Invest. , vol.126 , pp. 2933-2940
    • Lefkou, E.1    Mamopoulos, A.2    Dagklis, T.3    Vosnakis, C.4    Rousso, D.5    Girardi, G.6
  • 208
    • 85031396590 scopus 로고    scopus 로고
    • Detrimental roles of TNF-alpha in the antiphospholipid syndrome and de novo synthesis of antiphospholipid antibodies induced by biopharmaceuticals against TNF-alpha
    • Bećarević M., Detrimental roles of TNF-alpha in the antiphospholipid syndrome and de novo synthesis of antiphospholipid antibodies induced by biopharmaceuticals against TNF-alpha. J. Thromb. Thrombolysis 44 (2017), 565–570.
    • (2017) J. Thromb. Thrombolysis , vol.44 , pp. 565-570
    • Bećarević, M.1
  • 209
    • 85011695282 scopus 로고    scopus 로고
    • The role of anticoagulants in the prevention of pregnancy complications
    • Leaf, R.K., Connors, J.M., The role of anticoagulants in the prevention of pregnancy complications. Clin. Appl. Thromb. Hemost. 23 (2017), 116–123.
    • (2017) Clin. Appl. Thromb. Hemost. , vol.23 , pp. 116-123
    • Leaf, R.K.1    Connors, J.M.2
  • 210
    • 82955214541 scopus 로고    scopus 로고
    • Risk of thromboembolic events after recurrent spontan.eous abortion in antiphospholipid syndrome: a case-control study
    • Martinez-Zamora, M.A., Peralta, S., Creus, M., Tassies, D., Reverter, J.C., Espinosa, G., et al. Risk of thromboembolic events after recurrent spontan.eous abortion in antiphospholipid syndrome: a case-control study. Ann. Rheum. Dis. 71 (2012), 61–66.
    • (2012) Ann. Rheum. Dis. , vol.71 , pp. 61-66
    • Martinez-Zamora, M.A.1    Peralta, S.2    Creus, M.3    Tassies, D.4    Reverter, J.C.5    Espinosa, G.6
  • 211
    • 0034971358 scopus 로고    scopus 로고
    • High thrombosis rate after fetal loss in antiphospholipid syndrome: effective prophylaxis with aspirin
    • Erkan, D., Merrill, J.T., Yazici, Y., Sammaritano, L., Buyon, J.P., Lockshin, M.D., High thrombosis rate after fetal loss in antiphospholipid syndrome: effective prophylaxis with aspirin. Arthritis Rheum. 44 (2001), 1466–1467.
    • (2001) Arthritis Rheum. , vol.44 , pp. 1466-1467
    • Erkan, D.1    Merrill, J.T.2    Yazici, Y.3    Sammaritano, L.4    Buyon, J.P.5    Lockshin, M.D.6
  • 212
    • 84858671114 scopus 로고    scopus 로고
    • Comparative incidence of a first thrombotic event in purely obstetric antiphospholipid syndrome with pregnancy loss: the NOH-APS observational study
    • Gris, J.C., Bouvier, S., Molinari, N., Galanaud, J.P., Cochery-Nouvellon, E., Mercier, E., et al. Comparative incidence of a first thrombotic event in purely obstetric antiphospholipid syndrome with pregnancy loss: the NOH-APS observational study. Blood 119 (2012), 2624–2632.
    • (2012) Blood , vol.119 , pp. 2624-2632
    • Gris, J.C.1    Bouvier, S.2    Molinari, N.3    Galanaud, J.P.4    Cochery-Nouvellon, E.5    Mercier, E.6
  • 213
    • 20744448701 scopus 로고    scopus 로고
    • Recurrent miscarriage and long-term thrombosis risk: a case-control study
    • Quenby, S., Farquharson, R.G., Dawood, F., Hughes, A.M., Topping, J., Recurrent miscarriage and long-term thrombosis risk: a case-control study. Hum. Reprod. 20 (2005), 1729–1732.
    • (2005) Hum. Reprod. , vol.20 , pp. 1729-1732
    • Quenby, S.1    Farquharson, R.G.2    Dawood, F.3    Hughes, A.M.4    Topping, J.5
  • 216
    • 0026537186 scopus 로고
    • The catastrophic antiphospholipid syndrome
    • Asherson, R.A., The catastrophic antiphospholipid syndrome. J. Rheumatol. 19 (1992), 508–512.
    • (1992) J. Rheumatol. , vol.19 , pp. 508-512
    • Asherson, R.A.1
  • 217
    • 0038376616 scopus 로고    scopus 로고
    • Catastrophic Antiphospholipid Syndrome Registry Project Group, Catastrophic antiphospholipid syndrome: international consensus statement on classification criteria and treatment guidelines
    • Asherson, R.A., Cervera, R., de Groot, P.G., Erkan, D., Boffa, M.C., Piette, J.C., et al. Catastrophic Antiphospholipid Syndrome Registry Project Group, Catastrophic antiphospholipid syndrome: international consensus statement on classification criteria and treatment guidelines. Lupus 12 (2003), 530–534.
    • (2003) Lupus , vol.12 , pp. 530-534
    • Asherson, R.A.1    Cervera, R.2    de Groot, P.G.3    Erkan, D.4    Boffa, M.C.5    Piette, J.C.6
  • 219
    • 12344312949 scopus 로고    scopus 로고
    • Significance of valine/leucine247 polymorphism of beta2-glycoprotein I in antiphospholipid syndrome: increased reactivity of anti-beta2-glycoprotein I autoantibodies to the valine247 beta2-glycoprotein I variant
    • Yasuda, S., Atsumi, T., Matsuura, E., Kaihara, K., Yamamoto, D., Ichikawa, K., et al. Significance of valine/leucine247 polymorphism of beta2-glycoprotein I in antiphospholipid syndrome: increased reactivity of anti-beta2-glycoprotein I autoantibodies to the valine247 beta2-glycoprotein I variant. Arthritis Rheum. 52 (2005), 212–218.
    • (2005) Arthritis Rheum. , vol.52 , pp. 212-218
    • Yasuda, S.1    Atsumi, T.2    Matsuura, E.3    Kaihara, K.4    Yamamoto, D.5    Ichikawa, K.6
  • 220
    • 39649089396 scopus 로고    scopus 로고
    • Antiphospholipid antibodies, antiphospholipid syndrome and infections
    • Sène, D., Piette, J.C., Cacoub, P., Antiphospholipid antibodies, antiphospholipid syndrome and infections. Autoimmun. Rev. 7 (2008), 272–277.
    • (2008) Autoimmun. Rev. , vol.7 , pp. 272-277
    • Sène, D.1    Piette, J.C.2    Cacoub, P.3
  • 221
    • 84898881401 scopus 로고    scopus 로고
    • 14th international congress on antiphospholipid antibodies task force report on catastrophic antiphospholipid syndrome
    • Cervera, R., Rodríguez-Pintó I., Colafrancesco, S., Conti, F., Valesini, G., Rosário, C., et al. 14th international congress on antiphospholipid antibodies task force report on catastrophic antiphospholipid syndrome. Autoimmun. Rev. 13 (2014), 699–707.
    • (2014) Autoimmun. Rev. , vol.13 , pp. 699-707
    • Cervera, R.1    Rodríguez-Pintó, I.2    Colafrancesco, S.3    Conti, F.4    Valesini, G.5    Rosário, C.6
  • 222
    • 44849120143 scopus 로고    scopus 로고
    • A case of catastrophic antiphospholipid syndrome in an adolescent girl with parvovirus B19 infection
    • Canpolat, N., Topal, N., Civilibal, M., Caliskan, S., Sever, L., Kasapcopur, O., et al. A case of catastrophic antiphospholipid syndrome in an adolescent girl with parvovirus B19 infection. Clin. Pediatr. 47 (2008), 593–597.
    • (2008) Clin. Pediatr. , vol.47 , pp. 593-597
    • Canpolat, N.1    Topal, N.2    Civilibal, M.3    Caliskan, S.4    Sever, L.5    Kasapcopur, O.6
  • 223
    • 84886679576 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome (CAPS) induced by influenza A virus subtype H1N1
    • bcr2013200474–4
    • Durkin, M.L., Marchese, D., Robinson, M.D., Ramgopal, M., Catastrophic antiphospholipid syndrome (CAPS) induced by influenza A virus subtype H1N1. BMJ Case Rep., 2013, 2013 bcr2013200474–4.
    • (2013) BMJ Case Rep. , vol.2013
    • Durkin, M.L.1    Marchese, D.2    Robinson, M.D.3    Ramgopal, M.4
  • 224
    • 84962109861 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome triggered by fulminant chikungunya infection in a patient with systemic lupus erythematosus
    • 1044–4
    • Betancur, J.F., Navarro, E.P., Bravo Bonilla, J.H., Cortés, A.D., Vélez, J.D., Echeverry, A., et al. Catastrophic antiphospholipid syndrome triggered by fulminant chikungunya infection in a patient with systemic lupus erythematosus. Arthritis Rheum., 68, 2016 1044–4.
    • (2016) Arthritis Rheum. , vol.68
    • Betancur, J.F.1    Navarro, E.P.2    Bravo Bonilla, J.H.3    Cortés, A.D.4    Vélez, J.D.5    Echeverry, A.6
  • 225
    • 36248972264 scopus 로고    scopus 로고
    • The role of malignancies in patients with catastrophic anti-phospholipid (Asherson's) syndrome
    • Miesbach, W., Asherson, R.A., Cervera, R., Shoenfeld, Y., Gomez Puerta, J., Espinosa, G., et al. The role of malignancies in patients with catastrophic anti-phospholipid (Asherson's) syndrome. Clin. Rheumatol. 26 (2007), 2109–2114.
    • (2007) Clin. Rheumatol. , vol.26 , pp. 2109-2114
    • Miesbach, W.1    Asherson, R.A.2    Cervera, R.3    Shoenfeld, Y.4    Gomez Puerta, J.5    Espinosa, G.6
  • 226
    • 4644359641 scopus 로고    scopus 로고
    • The seventh ACCP conference on antithrombotic and thrombolytic therapy
    • Hirsh, J., Guyatt, G., Albers, G.W., Schünemann, H.J., The seventh ACCP conference on antithrombotic and thrombolytic therapy. Chest 126 (2004), 172S–173S.
    • (2004) Chest , vol.126 , pp. 172S-173S
    • Hirsh, J.1    Guyatt, G.2    Albers, G.W.3    Schünemann, H.J.4
  • 227
    • 0028234837 scopus 로고
    • A catastrophic antiphospholipid syndrome: the importance of high levels of warfarin anticoagulation
    • Ruffatti, A., De Silvestro, G., Ghirardello, A., Calligaro, A., Del Ross, T., Thiene, G., et al. A catastrophic antiphospholipid syndrome: the importance of high levels of warfarin anticoagulation. J. Intern. Med. 235 (1994), 81–83.
    • (1994) J. Intern. Med. , vol.235 , pp. 81-83
    • Ruffatti, A.1    De Silvestro, G.2    Ghirardello, A.3    Calligaro, A.4    Del Ross, T.5    Thiene, G.6
  • 228
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis
    • Auphan, N., DiDonato, J.A., Rosette, C., Helmberg, A., Karin, M., Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 270 (1995), 286–290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 229
    • 84864661522 scopus 로고    scopus 로고
    • Plasma exchange and immunoadsorption effectively remove antiphospholipid antibodies in pregnant patients with antiphospholipid syndrome
    • Bontadi, A., Ruffatti, A., Marson, P., Tison, T., Tonello, M., Hoxha, A., et al. Plasma exchange and immunoadsorption effectively remove antiphospholipid antibodies in pregnant patients with antiphospholipid syndrome. J. Clin. Apher. 27 (2012), 200–204.
    • (2012) J. Clin. Apher. , vol.27 , pp. 200-204
    • Bontadi, A.1    Ruffatti, A.2    Marson, P.3    Tison, T.4    Tonello, M.5    Hoxha, A.6
  • 230
    • 84881381644 scopus 로고    scopus 로고
    • Guidelines on the use of therapeutic apheresis in clinical practice-evidence-based approach from the Writing Committee of the American Society for Apheresis: the sixth special issue
    • Schwartz, J., Winters, J.L., Padmanabhan, A., Balogun, R.-A., Delaney, M., Linenberger, M.L., et al. Guidelines on the use of therapeutic apheresis in clinical practice-evidence-based approach from the Writing Committee of the American Society for Apheresis: the sixth special issue. J. Clin. Apher. 28 (2013), 145–284.
    • (2013) J. Clin. Apher. , vol.28 , pp. 145-284
    • Schwartz, J.1    Winters, J.L.2    Padmanabhan, A.3    Balogun, R.-A.4    Delaney, M.5    Linenberger, M.L.6
  • 231
    • 22144480903 scopus 로고    scopus 로고
    • The role of therapeutic plasma exchange in the catastrophic antiphospholipid syndrome
    • Uthman, I., Shamseddine, A., Taher, A., The role of therapeutic plasma exchange in the catastrophic antiphospholipid syndrome. Transfus. Apher. Sci. 33 (2005), 11–17.
    • (2005) Transfus. Apher. Sci. , vol.33 , pp. 11-17
    • Uthman, I.1    Shamseddine, A.2    Taher, A.3
  • 232
    • 46949086823 scopus 로고    scopus 로고
    • Plasma exchange for the management of the catastrophic antiphospholipid syndrome: importance of the type of fluid replacement
    • Marson, P., Bagatella, P., Bortolati, M., Tison, T., De Silvestro, G., Fabris, F., et al. Plasma exchange for the management of the catastrophic antiphospholipid syndrome: importance of the type of fluid replacement. J. Intern. Med. 264 (2008), 201–203.
    • (2008) J. Intern. Med. , vol.264 , pp. 201-203
    • Marson, P.1    Bagatella, P.2    Bortolati, M.3    Tison, T.4    De Silvestro, G.5    Fabris, F.6
  • 233
    • 66349107412 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome: treatment, prognosis, and the risk of relapse
    • Bucciarelli, S., Erkan, D., Espinosa, G., Cervera, R., Catastrophic antiphospholipid syndrome: treatment, prognosis, and the risk of relapse. Clin. Rev. Allergy Immunol. 36 (2009), 80–84.
    • (2009) Clin. Rev. Allergy Immunol. , vol.36 , pp. 80-84
    • Bucciarelli, S.1    Erkan, D.2    Espinosa, G.3    Cervera, R.4
  • 234
    • 84881551069 scopus 로고    scopus 로고
    • Catastrophic Antiphospholipid Syndrome (CAPS) Registry Project Group (European Forum on Antiphospholipid Antibodies). Rituximab use in the catastrophic antiphospholipid syndrome: descriptive analysis of the CAPS registry patients receiving rituximab
    • Berman, H., Rodríguez-Pintó I., Cervera, R., Morel, N., Costedoat-Chalumeau, N., Erkan, D., et al. Catastrophic Antiphospholipid Syndrome (CAPS) Registry Project Group (European Forum on Antiphospholipid Antibodies). Rituximab use in the catastrophic antiphospholipid syndrome: descriptive analysis of the CAPS registry patients receiving rituximab. Autoimmun. Rev. 12 (2013), 1085–1090.
    • (2013) Autoimmun. Rev. , vol.12 , pp. 1085-1090
    • Berman, H.1    Rodríguez-Pintó, I.2    Cervera, R.3    Morel, N.4    Costedoat-Chalumeau, N.5    Erkan, D.6
  • 236
    • 45549093797 scopus 로고    scopus 로고
    • Successful treatment of catastrophic antiphospholipid antibody syndrome (CAPS) associated with splenic marginal-zone lymphoma with low-molecular weight heparin, rituximab and bendamustine
    • Manner, H., Jung, B., Tonassi, L., Hackenberg, U., Plum, N., Josten, K.M., et al. Successful treatment of catastrophic antiphospholipid antibody syndrome (CAPS) associated with splenic marginal-zone lymphoma with low-molecular weight heparin, rituximab and bendamustine. Am. J.Med. Sci. 335 (2008), 394–397.
    • (2008) Am. J.Med. Sci. , vol.335 , pp. 394-397
    • Manner, H.1    Jung, B.2    Tonassi, L.3    Hackenberg, U.4    Plum, N.5    Josten, K.M.6
  • 237
    • 46849100463 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome mimicking a malignant pancreatic tumour–a case report
    • van Wissen, S., Bastiaansen, B.A.J., Stroobants, A.K., van den Dool, E.J., Idu, M.M., Levi, M., et al. Catastrophic antiphospholipid syndrome mimicking a malignant pancreatic tumour–a case report. Lupus 17 (2008), 586–590.
    • (2008) Lupus , vol.17 , pp. 586-590
    • van Wissen, S.1    Bastiaansen, B.A.J.2    Stroobants, A.K.3    van den Dool, E.J.4    Idu, M.M.5    Levi, M.6
  • 240
    • 77951025811 scopus 로고    scopus 로고
    • Osteonecrosis secondary to antiphospholipid syndrome: a case report, review of the literature, and treatment strategy
    • Haque, W., Kadikoy, H., Pacha, O., Maliakkal, J., Hoang, V., Abdellatif, A., Osteonecrosis secondary to antiphospholipid syndrome: a case report, review of the literature, and treatment strategy. Rheumatol. Int. 30 (2010), 719–723.
    • (2010) Rheumatol. Int. , vol.30 , pp. 719-723
    • Haque, W.1    Kadikoy, H.2    Pacha, O.3    Maliakkal, J.4    Hoang, V.5    Abdellatif, A.6
  • 241
    • 84940363650 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome with severe acute thrombotic microangiopathy and hemorrhagic complications
    • Vieregge, G.B., Harrington, T.J., Andrews, D.M., Carpintero, M.F., Green, D.F., Nayer, A., Catastrophic antiphospholipid syndrome with severe acute thrombotic microangiopathy and hemorrhagic complications. Case Rep. Med. 2013 (2013), 915309–915316.
    • (2013) Case Rep. Med. , vol.2013 , pp. 915309-915316
    • Vieregge, G.B.1    Harrington, T.J.2    Andrews, D.M.3    Carpintero, M.F.4    Green, D.F.5    Nayer, A.6
  • 242
    • 84962619678 scopus 로고    scopus 로고
    • Vascular endothelial cell function in catastrophic antiphospholipid syndrome: a case report and review of the literature
    • 710365–4
    • Routy, B., Huynh, T., Fraser, R., Séguin, C., Vascular endothelial cell function in catastrophic antiphospholipid syndrome: a case report and review of the literature. Case. Rep. Hematol., 2013, 2013 710365–4.
    • (2013) Case. Rep. Hematol. , vol.2013
    • Routy, B.1    Huynh, T.2    Fraser, R.3    Séguin, C.4
  • 243
    • 85044691671 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome: a case series
    • Shiber, S., Yair, M., Catastrophic antiphospholipid syndrome: a case series. Isr. Med. Assoc. J. 15 (2013), 481–484.
    • (2013) Isr. Med. Assoc. J. , vol.15 , pp. 481-484
    • Shiber, S.1    Yair, M.2
  • 244
    • 84942082065 scopus 로고    scopus 로고
    • A case of catastrophic antiphospholipid syndrome: first report with advanced cardiac imaging using MRI
    • Rosenbaum, A.N., Anavekar, N.S., Ernste, F.C., Mankad, S.V., Le, R.-J., Manocha, K.K., et al. A case of catastrophic antiphospholipid syndrome: first report with advanced cardiac imaging using MRI. Lupus 24 (2015), 1338–1341.
    • (2015) Lupus , vol.24 , pp. 1338-1341
    • Rosenbaum, A.N.1    Anavekar, N.S.2    Ernste, F.C.3    Mankad, S.V.4    Le, R.-J.5    Manocha, K.K.6
  • 245
    • 84929709351 scopus 로고    scopus 로고
    • A therapeutic challenge: catastrophic anti-phospholipid syndrome with diffuse alveolar haemorrhage
    • Martis, N., Blanchouin, E., Lazdunski, R., Lechtman, S., Robert, A., Hyvernat, H., et al. A therapeutic challenge: catastrophic anti-phospholipid syndrome with diffuse alveolar haemorrhage. Immunol. Res. 62 (2015), 222–224.
    • (2015) Immunol. Res. , vol.62 , pp. 222-224
    • Martis, N.1    Blanchouin, E.2    Lazdunski, R.3    Lechtman, S.4    Robert, A.5    Hyvernat, H.6
  • 246
    • 84991380084 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome associated with systemic lupus erythematosus treated with rituximab: case report and a review of the literature
    • Sukara, G., Baresi, M., Sentic, M., Brcic, L., Anic, B., Catastrophic antiphospholipid syndrome associated with systemic lupus erythematosus treated with rituximab: case report and a review of the literature. Acta. Reumatol. Port 40 (2015), 169–175.
    • (2015) Acta. Reumatol. Port , vol.40 , pp. 169-175
    • Sukara, G.1    Baresi, M.2    Sentic, M.3    Brcic, L.4    Anic, B.5
  • 247
    • 84947080272 scopus 로고    scopus 로고
    • Atypical Subacute recurrence of catastrophic antiphospholipid syndrome in a Japanese female patient
    • Horikoshi, M., Inokuma, S., Matsubara, E., Honda, Y., Okada, R., Kobuna, M., et al. Atypical Subacute recurrence of catastrophic antiphospholipid syndrome in a Japanese female patient. Intern. Med. 54 (2015), 2923–2927.
    • (2015) Intern. Med. , vol.54 , pp. 2923-2927
    • Horikoshi, M.1    Inokuma, S.2    Matsubara, E.3    Honda, Y.4    Okada, R.5    Kobuna, M.6
  • 248
    • 85046593981 scopus 로고    scopus 로고
    • ŞE. Tunç Catastrophic antiphospholipid syndrome treated with rituximab: a case report
    • Doğru, A., Ugan, Y., Şahin, M., Karahan, N., ŞE. Tunç Catastrophic antiphospholipid syndrome treated with rituximab: a case report. Eur. J. Rheumatol. 4 (2017), 145–147.
    • (2017) Eur. J. Rheumatol. , vol.4 , pp. 145-147
    • Doğru, A.1    Ugan, Y.2    Şahin, M.3    Karahan, N.4
  • 249
    • 77951853702 scopus 로고    scopus 로고
    • Eculizumab and renal transplantation in a patient with CAPS
    • Lonze, B.E., Singer, A.L., Montgomery, R.A., Eculizumab and renal transplantation in a patient with CAPS. N. Engl. J. Med. 362 (2010), 1744–1775.
    • (2010) N. Engl. J. Med. , vol.362 , pp. 1744-1775
    • Lonze, B.E.1    Singer, A.L.2    Montgomery, R.A.3
  • 250
    • 84864485595 scopus 로고    scopus 로고
    • Brief report: induction of sustained remission in recurrent catastrophic antiphospholipid syndrome via inhibition of terminal complement with eculizumab
    • 2719–2273
    • Shapira, I., Andrade, D., Allen, S.L., Salmon, J.E., Brief report: induction of sustained remission in recurrent catastrophic antiphospholipid syndrome via inhibition of terminal complement with eculizumab. Arthritis Rheum., 64, 2012 2719–2273.
    • (2012) Arthritis Rheum. , vol.64
    • Shapira, I.1    Andrade, D.2    Allen, S.L.3    Salmon, J.E.4
  • 251
    • 84917728306 scopus 로고    scopus 로고
    • Efficacy of eculizumab in a patient with immunoadsorption-dependent catastrophic antiphospholipid syndrome: a case report
    • Kronbichler, A., Frank, R., Kirschfink, M., Szilágyi, Á., Csuka, D., Prohászka, Z., et al. Efficacy of eculizumab in a patient with immunoadsorption-dependent catastrophic antiphospholipid syndrome: a case report. Medicine, 93, 2014, e143.
    • (2014) Medicine , vol.93 , pp. e143
    • Kronbichler, A.1    Frank, R.2    Kirschfink, M.3    Szilágyi, Á.4    Csuka, D.5    Prohászka, Z.6
  • 252
    • 84936987706 scopus 로고    scopus 로고
    • 36-year-old female with catastrophic antiphospholipid syndrome treated with eculizumab: a case report and review of literature
    • Strakhan, M., Hurtado-Sbordoni, M., Galeas, N., Bakirhan, K., Alexis, K., Elrafei, T., 36-year-old female with catastrophic antiphospholipid syndrome treated with eculizumab: a case report and review of literature. Case. Rep. Hematol. 2014 (2014), 704371–704377.
    • (2014) Case. Rep. Hematol. , vol.2014 , pp. 704371-704377
    • Strakhan, M.1    Hurtado-Sbordoni, M.2    Galeas, N.3    Bakirhan, K.4    Alexis, K.5    Elrafei, T.6
  • 253
    • 84940905884 scopus 로고    scopus 로고
    • Eculizumab induces sustained remission in a patient with refractory primary catastrophic antiphospholipid syndrome
    • Zikos, T.A., Sokolove, J., Ahuja, N., Berube, C., Eculizumab induces sustained remission in a patient with refractory primary catastrophic antiphospholipid syndrome. J. Clin. Rheumatol. 21 (2015), 311–313.
    • (2015) J. Clin. Rheumatol. , vol.21 , pp. 311-313
    • Zikos, T.A.1    Sokolove, J.2    Ahuja, N.3    Berube, C.4
  • 254
    • 84961960857 scopus 로고    scopus 로고
    • A case of relapsing and refractory catastrophic anti-phospholipid syndrome successfully managed with eculizumab, a complement 5 inhibitor
    • Wig, S., Chan, M., Thachil, J., Bruce, I., Barnes, T., A case of relapsing and refractory catastrophic anti-phospholipid syndrome successfully managed with eculizumab, a complement 5 inhibitor. Rheumatology 55 (2016), 382–384.
    • (2016) Rheumatology , vol.55 , pp. 382-384
    • Wig, S.1    Chan, M.2    Thachil, J.3    Bruce, I.4    Barnes, T.5
  • 255
    • 79551556480 scopus 로고    scopus 로고
    • Primary thrombosis prophylaxis in antiphospholipid antibody-positive patients: where do we stand?
    • Barbhaiya, M., Erkan, D., Primary thrombosis prophylaxis in antiphospholipid antibody-positive patients: where do we stand?. Curr. Rheumatol. Rep. 13 (2011), 59–69.
    • (2011) Curr. Rheumatol. Rep. , vol.13 , pp. 59-69
    • Barbhaiya, M.1    Erkan, D.2
  • 256
    • 84861480764 scopus 로고    scopus 로고
    • Thromboprophylaxis in carriers of antiphospholipid antibodies (APL) without previous thrombosis: “Pros” and “Cons”
    • Ceccarelli, F., Chighizola, C., Finazzi, G., Meroni, P.L., Valesini, G., Thromboprophylaxis in carriers of antiphospholipid antibodies (APL) without previous thrombosis: “Pros” and “Cons”. Autoimmun. Rev. 11 (2012), 568–571.
    • (2012) Autoimmun. Rev. , vol.11 , pp. 568-571
    • Ceccarelli, F.1    Chighizola, C.2    Finazzi, G.3    Meroni, P.L.4    Valesini, G.5
  • 257
    • 84921026907 scopus 로고    scopus 로고
    • Patient-level analysis of five international cohorts further confirms the efficacy of aspirin for the primary prevention of thrombosis in patients with antiphospholipid antibodies
    • Arnaud, L., Mathian, A., Devilliers, H., Ruffatti, A., Tektonidou, M., Forastiero, R., et al. Patient-level analysis of five international cohorts further confirms the efficacy of aspirin for the primary prevention of thrombosis in patients with antiphospholipid antibodies. Autoimmun. Rev. 14 (2015), 192–200.
    • (2015) Autoimmun. Rev. , vol.14 , pp. 192-200
    • Arnaud, L.1    Mathian, A.2    Devilliers, H.3    Ruffatti, A.4    Tektonidou, M.5    Forastiero, R.6
  • 258
    • 84892535614 scopus 로고    scopus 로고
    • Low-dose aspirin vs low-dose aspirin plus low- intensity warfarin in thromboprophylaxis: a prospective, multicentre, randomized, open, controlled trial in patients positive for antiphospholipid antibodies (ALIWAPAS)
    • Cuadrado, M.J., Bertolaccini, M.L., Seed, P.T., Tektonidou, M.G., Aguirre, A., Mico, L., et al. Low-dose aspirin vs low-dose aspirin plus low- intensity warfarin in thromboprophylaxis: a prospective, multicentre, randomized, open, controlled trial in patients positive for antiphospholipid antibodies (ALIWAPAS). Rheumatology 53 (2014), 275–284.
    • (2014) Rheumatology , vol.53 , pp. 275-284
    • Cuadrado, M.J.1    Bertolaccini, M.L.2    Seed, P.T.3    Tektonidou, M.G.4    Aguirre, A.5    Mico, L.6
  • 260
    • 3442901073 scopus 로고    scopus 로고
    • Antiphospholipid syndrome and asymptomatic carriers of antiphospholipid antibody: prospective analysis of 404 individuals
    • Giron-Gonzalez, J.A., Garcia del Rio, E., Rodriguez, C., Rodriguez-Martorell, J., Serrano, A., Antiphospholipid syndrome and asymptomatic carriers of antiphospholipid antibody: prospective analysis of 404 individuals. J. Rheumatol. 31 (2004), 1560–1567.
    • (2004) J. Rheumatol. , vol.31 , pp. 1560-1567
    • Giron-Gonzalez, J.A.1    Garcia del Rio, E.2    Rodriguez, C.3    Rodriguez-Martorell, J.4    Serrano, A.5
  • 261
    • 38749089852 scopus 로고    scopus 로고
    • EULAR recommendations for the management of systemic lupus erythematosus, report of a task force of the EULAR standing committee for international clinical studies including therapeutics
    • Bertsias, G., Ioannidis, J.P.A., Boletis, J., Bombardieri, S., Cervera, R., Dostál, C., et al. EULAR recommendations for the management of systemic lupus erythematosus, report of a task force of the EULAR standing committee for international clinical studies including therapeutics. Ann. Rheum. Dis. 67 (2008), 195–205.
    • (2008) Ann. Rheum. Dis. , vol.67 , pp. 195-205
    • Bertsias, G.1    Ioannidis, J.P.A.2    Boletis, J.3    Bombardieri, S.4    Cervera, R.5    Dostál, C.6
  • 262
    • 77956044827 scopus 로고    scopus 로고
    • Therapeutic opportunities in systemic lupus erythematosus: state of the art and prospects for the new decade
    • Bertsias, G.K., Salmon, J.E., Boumpas, D.T., Therapeutic opportunities in systemic lupus erythematosus: state of the art and prospects for the new decade. Ann. Rheum. Dis. 69 (2010), 1603–1611.
    • (2010) Ann. Rheum. Dis. , vol.69 , pp. 1603-1611
    • Bertsias, G.K.1    Salmon, J.E.2    Boumpas, D.T.3
  • 263
    • 73449120372 scopus 로고    scopus 로고
    • Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review
    • Ruiz-Irastorza, G., Ramos-Casals, M., Brito-Zeron, P., Khamashta, M.A., Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review. Ann. Rheum. Dis. 69 (2010), 20–28.
    • (2010) Ann. Rheum. Dis. , vol.69 , pp. 20-28
    • Ruiz-Irastorza, G.1    Ramos-Casals, M.2    Brito-Zeron, P.3    Khamashta, M.A.4
  • 264
    • 85039061628 scopus 로고    scopus 로고
    • The effect of hydroxychloroquine on haemostasis, complement, inflammation and angiogenesis in patients with antiphospholipid antibodies
    • Schreiber, K., Breen, K., Parmar, K., Rand, J.H., Wu, X.-X., Hunt, B.J., The effect of hydroxychloroquine on haemostasis, complement, inflammation and angiogenesis in patients with antiphospholipid antibodies. Rheumatology 57 (2018), 120–124.
    • (2018) Rheumatology , vol.57 , pp. 120-124
    • Schreiber, K.1    Breen, K.2    Parmar, K.3    Rand, J.H.4    Wu, X.-X.5    Hunt, B.J.6
  • 265
    • 85042129382 scopus 로고    scopus 로고
    • Hydroxychloroquine in the primary thrombosis prophylaxis of antiphospholipid antibody positive patients without systemic autoimmune disease
    • 961203317724219
    • Erkan, D., Unlu, O., Sciascia, S., Belmont, H.M., Branch, D.W., Cuadrado, M.J., et al. Hydroxychloroquine in the primary thrombosis prophylaxis of antiphospholipid antibody positive patients without systemic autoimmune disease. Lupus, 31, 2017 961203317724219.
    • (2017) Lupus , vol.31
    • Erkan, D.1    Unlu, O.2    Sciascia, S.3    Belmont, H.M.4    Branch, D.W.5    Cuadrado, M.J.6
  • 266
    • 63649095045 scopus 로고    scopus 로고
    • Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial
    • Ridker, P.M., Danielson, E., Fonseca, F.A., Genest, J., Gotto, A.M., Kastelein, J.J., et al. Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial. Lancet 373 (2009), 1175–1182.
    • (2009) Lancet , vol.373 , pp. 1175-1182
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.3    Genest, J.4    Gotto, A.M.5    Kastelein, J.J.6
  • 268
    • 84899916939 scopus 로고    scopus 로고
    • A prospective open-label pilot study of fluvastatin on proinflammatory and prothrombotic biomarkers in antiphospholipid antibody positive patients
    • Erkan, D., Willis, R., Murthy, V.L., Basra, G., Vega, J., Ruiz-Limon, P., et al. A prospective open-label pilot study of fluvastatin on proinflammatory and prothrombotic biomarkers in antiphospholipid antibody positive patients. Ann. Rheum. Dis. 73 (2014), 1176–1180.
    • (2014) Ann. Rheum. Dis. , vol.73 , pp. 1176-1180
    • Erkan, D.1    Willis, R.2    Murthy, V.L.3    Basra, G.4    Vega, J.5    Ruiz-Limon, P.6
  • 270
    • 78650676621 scopus 로고    scopus 로고
    • Vitamin D: an instrumental factor in the antiphospholipid syndrome by inhibition of tissue factor expression
    • Agmon-Levin, N., Blank, M., Zandman-Goddard, G., Orbach, H., Meroni, P.L., Tincani, A., et al. Vitamin D: an instrumental factor in the antiphospholipid syndrome by inhibition of tissue factor expression. Ann. Rheum. Dis. 70 (2011), 145–150.
    • (2011) Ann. Rheum. Dis. , vol.70 , pp. 145-150
    • Agmon-Levin, N.1    Blank, M.2    Zandman-Goddard, G.3    Orbach, H.4    Meroni, P.L.5    Tincani, A.6
  • 271
    • 84871434258 scopus 로고    scopus 로고
    • Low levels of vitamin D are common in primary antiphospholipid syndrome with thrombotic disease
    • Piantoni, S., Andreoli, L., Allegri, F., Meroni, P.L., Tincani, A., Low levels of vitamin D are common in primary antiphospholipid syndrome with thrombotic disease. Reumatismo 64 (2012), 307–313.
    • (2012) Reumatismo , vol.64 , pp. 307-313
    • Piantoni, S.1    Andreoli, L.2    Allegri, F.3    Meroni, P.L.4    Tincani, A.5
  • 272
    • 85013998847 scopus 로고    scopus 로고
    • Oxidative stress in the pathogenesis of atherothrombosis associated with anti-phospholipid syndrome and systemic lupus erythematosus: new therapeutic approaches
    • López-Pedrera, C., Barbarroja, N., Jimenez-Gomez, Y., Collantes-Estevez, E., Aguirre, M.A., Cuadrado, M.J., Oxidative stress in the pathogenesis of atherothrombosis associated with anti-phospholipid syndrome and systemic lupus erythematosus: new therapeutic approaches. Rheumatology 55 (2016), 2096–2108.
    • (2016) Rheumatology , vol.55 , pp. 2096-2108
    • López-Pedrera, C.1    Barbarroja, N.2    Jimenez-Gomez, Y.3    Collantes-Estevez, E.4    Aguirre, M.A.5    Cuadrado, M.J.6
  • 273
    • 84862496402 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q(10) treatment
    • Perez-Sanchez, C., Ruiz-Limon, P., Aguirre, M.A., Bertolaccini, M.L., Khamashta, M.A., Rodriguez-Ariza, A., et al. Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q(10) treatment. Blood 119 (2012), 5859–5870.
    • (2012) Blood , vol.119 , pp. 5859-5870
    • Perez-Sanchez, C.1    Ruiz-Limon, P.2    Aguirre, M.A.3    Bertolaccini, M.L.4    Khamashta, M.A.5    Rodriguez-Ariza, A.6
  • 275
    • 84875866781 scopus 로고    scopus 로고
    • Treatment of 139 pregnancies in antiphospholipid-positive women not fulfilling criteria for antiphospholipid syndrome: a retrospective study
    • Del Ross, T., Ruffatti, A., Visentin, M.S., Tonello, M., Calligaro, A., Favaro, M., et al. Treatment of 139 pregnancies in antiphospholipid-positive women not fulfilling criteria for antiphospholipid syndrome: a retrospective study. J. Rheumatol. 40 (2013), 425–429.
    • (2013) J. Rheumatol. , vol.40 , pp. 425-429
    • Del Ross, T.1    Ruffatti, A.2    Visentin, M.S.3    Tonello, M.4    Calligaro, A.5    Favaro, M.6
  • 276
    • 84882990161 scopus 로고    scopus 로고
    • Persistent antiphospholipid antibodies do not contribute to adverse pregnancy outcomes
    • Soh, M.C., Pasupathy, D., Gray, G., Nelson-Piercy, C., Persistent antiphospholipid antibodies do not contribute to adverse pregnancy outcomes. Rheumatology 52 (2013), 1642–1647.
    • (2013) Rheumatology , vol.52 , pp. 1642-1647
    • Soh, M.C.1    Pasupathy, D.2    Gray, G.3    Nelson-Piercy, C.4
  • 277
    • 85046587587 scopus 로고    scopus 로고
    • A multicenter prospective evaluation of the risk profile in pregnant patients with persistent positivity for antiphospholipid antibodies (APL)
    • Fredi, M., Aggogeri, E., Bettiga, E., Andreoli, L., Lazzaroni, M.G., Le Guern, V., et al. A multicenter prospective evaluation of the risk profile in pregnant patients with persistent positivity for antiphospholipid antibodies (APL). Ann. Rheum. Dis., 74, 2015, 575.
    • (2015) Ann. Rheum. Dis. , vol.74 , pp. 575
    • Fredi, M.1    Aggogeri, E.2    Bettiga, E.3    Andreoli, L.4    Lazzaroni, M.G.5    Le Guern, V.6
  • 278
    • 85046594354 scopus 로고    scopus 로고
    • Risk factors for adverse pregnancy outcome in antiphospholipid antibodies carriers: results from a multicenter Italian cohort over 20 years of experience
    • Lazzaroni, M.G., Andreoli, L., Chighizola, C.B., Ross, T.Del, Gerosa, M., Kuzenko, A., et al. Risk factors for adverse pregnancy outcome in antiphospholipid antibodies carriers: results from a multicenter Italian cohort over 20 years of experience. Ann. Rheum. Dis., 76, 2017, 70.
    • (2017) Ann. Rheum. Dis. , vol.76 , pp. 70
    • Lazzaroni, M.G.1    Andreoli, L.2    Chighizola, C.B.3    Ross, T.D.4    Gerosa, M.5    Kuzenko, A.6
  • 279
    • 0030988198 scopus 로고    scopus 로고
    • Do low-risk pregnant women with antiphospholipid antibodies need to be treated? Organizing Group of the Antiphospholipid Antibody Treatment Trial
    • Cowchock, S., Reece, E.A., Do low-risk pregnant women with antiphospholipid antibodies need to be treated? Organizing Group of the Antiphospholipid Antibody Treatment Trial. Am. J. Obstet. Gynecol. 176 (1997), 1099–1100.
    • (1997) Am. J. Obstet. Gynecol. , vol.176 , pp. 1099-1100
    • Cowchock, S.1    Reece, E.A.2
  • 280
    • 77952710588 scopus 로고    scopus 로고
    • Observational study of pregnant women with a previous spontaneous abortion before the 10th gestation week with and without antiphospholipid antibodies
    • Chauleur, C., Galanaud, J.P., Alonso, S., Cochery-Nouvellon, E., Balducchi, J.P., Marès, P., et al. Observational study of pregnant women with a previous spontaneous abortion before the 10th gestation week with and without antiphospholipid antibodies. J. Thromb. Haemostasis 8 (2010), 699–706.
    • (2010) J. Thromb. Haemostasis , vol.8 , pp. 699-706
    • Chauleur, C.1    Galanaud, J.P.2    Alonso, S.3    Cochery-Nouvellon, E.4    Balducchi, J.P.5    Marès, P.6
  • 281
    • 84861560222 scopus 로고    scopus 로고
    • The European registry on obstetric antiphospholipid syndrome (EUROAPS): a preliminary first year report
    • Alijotas-Reig, J., Ferrer-Oliveras, R., EUROAPS Study Group, The European registry on obstetric antiphospholipid syndrome (EUROAPS): a preliminary first year report. Lupus 21 (2012), 766–768.
    • (2012) Lupus , vol.21 , pp. 766-768
    • Alijotas-Reig, J.1    Ferrer-Oliveras, R.2    EUROAPS Study Group3
  • 282
    • 84995578428 scopus 로고    scopus 로고
    • Prevention & treatment of obstetrical complications in APS: is hydroxychloroquine the Holy Grail we are looking for?
    • Meroni, P.L., Prevention & treatment of obstetrical complications in APS: is hydroxychloroquine the Holy Grail we are looking for?. J. Autoimmun. 75 (2016), 1–5.
    • (2016) J. Autoimmun. , vol.75 , pp. 1-5
    • Meroni, P.L.1
  • 284
    • 84892438423 scopus 로고    scopus 로고
    • Effect of hydroxychloroquine on antiphospholipid antibody-induced changes in first trimester trophoblast function
    • Albert, C.R., Schlesinger, W.J., Viall, C.A., et al. Effect of hydroxychloroquine on antiphospholipid antibody-induced changes in first trimester trophoblast function. Am. J. Reprod. Immunol. 71 (2014), 154–164.
    • (2014) Am. J. Reprod. Immunol. , vol.71 , pp. 154-164
    • Albert, C.R.1    Schlesinger, W.J.2    Viall, C.A.3
  • 285
    • 67749101879 scopus 로고    scopus 로고
    • Laboratory criteria of the obstetrical antiphospholipid syndrome. Data from a multicentric prospective European women cohort
    • Boffa, M.C., Boinot, C., de Carolis, S., Rovere-Querini, P., Aurousseau, M.H., Allegri, F., et al. Laboratory criteria of the obstetrical antiphospholipid syndrome. Data from a multicentric prospective European women cohort. Thromb. Haemostasis 102 (2009), 25–28.
    • (2009) Thromb. Haemostasis , vol.102 , pp. 25-28
    • Boffa, M.C.1    Boinot, C.2    de Carolis, S.3    Rovere-Querini, P.4    Aurousseau, M.H.5    Allegri, F.6
  • 286
    • 52449102771 scopus 로고    scopus 로고
    • Influence of different IgG anticardiolipin antibody cut-off values on antiphospholipid syndrome classification
    • Ruffatti, A., Olivieri, S., Tonello, M., Bortolati, M., Bison, E., Salvan, E., et al. Influence of different IgG anticardiolipin antibody cut-off values on antiphospholipid syndrome classification. J. Thromb. Haemostasis 6 (2008), 1693–1696.
    • (2008) J. Thromb. Haemostasis , vol.6 , pp. 1693-1696
    • Ruffatti, A.1    Olivieri, S.2    Tonello, M.3    Bortolati, M.4    Bison, E.5    Salvan, E.6
  • 287
    • 84871552087 scopus 로고    scopus 로고
    • Diagnosis of antiphospholipid syndrome in routine clinical practice
    • Gardiner, C., Hills, J., Machin, S.J., Cohen, H., Diagnosis of antiphospholipid syndrome in routine clinical practice. Lupus 22 (2013), 18–25.
    • (2013) Lupus , vol.22 , pp. 18-25
    • Gardiner, C.1    Hills, J.2    Machin, S.J.3    Cohen, H.4
  • 288
    • 85046586690 scopus 로고    scopus 로고
    • The risk of obstetric complications and the effects of treatment in women with low titer and medium-high titer anti-phospholipid antibodies
    • Chighizola, C.B., Raimondo, M.G., Comerio, C., Pregnolato, F., Sobrino, C., Trespidi, L., et al. The risk of obstetric complications and the effects of treatment in women with low titer and medium-high titer anti-phospholipid antibodies. Arthritis Rheum., 68, 2016.
    • (2016) Arthritis Rheum. , vol.68
    • Chighizola, C.B.1    Raimondo, M.G.2    Comerio, C.3    Pregnolato, F.4    Sobrino, C.5    Trespidi, L.6
  • 289
    • 84908420463 scopus 로고    scopus 로고
    • Recurrent miscarriages in women not fulfilling classification criteria for antiphospholipid antibody syndrome
    • Proietta, M., Ferrero, S., Ferri, L., Cifani, N., Bruno, G., Del Porto, F., Recurrent miscarriages in women not fulfilling classification criteria for antiphospholipid antibody syndrome. Int. J. Immunopathol. Pharmacol. 27 (2014), 429–432.
    • (2014) Int. J. Immunopathol. Pharmacol. , vol.27 , pp. 429-432
    • Proietta, M.1    Ferrero, S.2    Ferri, L.3    Cifani, N.4    Bruno, G.5    Del Porto, F.6
  • 292
    • 84902193546 scopus 로고    scopus 로고
    • 14th international congress on antiphospholipid antibodies task force report on obstetric antiphospholipid syndrome
    • de Jesus, G.R., Agmon-Levin, N., Andrade, C.A., Andreoli, L., Chighizola, C.B., Porter, T.F., et al. 14th international congress on antiphospholipid antibodies task force report on obstetric antiphospholipid syndrome. Autoimmun. Rev. 13 (2014), 795–813.
    • (2014) Autoimmun. Rev. , vol.13 , pp. 795-813
    • de Jesus, G.R.1    Agmon-Levin, N.2    Andrade, C.A.3    Andreoli, L.4    Chighizola, C.B.5    Porter, T.F.6
  • 293
    • 0026659095 scopus 로고
    • Antiphospholipid thrombosis: clinical course after the first thrombotic event in 70 patients
    • Rosove, M.H., Brewer, P.M., Antiphospholipid thrombosis: clinical course after the first thrombotic event in 70 patients. Ann. Intern. Med. 117 (1992), 303–308.
    • (1992) Ann. Intern. Med. , vol.117 , pp. 303-308
    • Rosove, M.H.1    Brewer, P.M.2
  • 294
    • 0027203896 scopus 로고
    • Patients with antiphospholipid antibodies and venous thrombosis should receive long term anticoagulant treatment
    • Derksen, R.H., de Groot, P.G., Kater, L., Nieuwenhuis, H.K., Patients with antiphospholipid antibodies and venous thrombosis should receive long term anticoagulant treatment. Ann. Rheum. Dis. 52 (1993), 689–692.
    • (1993) Ann. Rheum. Dis. , vol.52 , pp. 689-692
    • Derksen, R.H.1    de Groot, P.G.2    Kater, L.3    Nieuwenhuis, H.K.4
  • 296
    • 0029982331 scopus 로고    scopus 로고
    • Antiphospholipid antibodies, recurrent thromboembolism, and intensity of warfarin anticoagulation
    • Prandoni, P., Simioni, P., Girolami, A., Antiphospholipid antibodies, recurrent thromboembolism, and intensity of warfarin anticoagulation. Thromb. Haemostasis, 75, 1996, 859.
    • (1996) Thromb. Haemostasis , vol.75 , pp. 859
    • Prandoni, P.1    Simioni, P.2    Girolami, A.3
  • 297
    • 0031049488 scopus 로고    scopus 로고
    • Anticardiolipin antibodies and recurrent thromboembolism
    • Rance, A., Emmerich, J., Fiessinger, J.N., Anticardiolipin antibodies and recurrent thromboembolism. Thromb. Haemostasis 77 (1997), 221–222.
    • (1997) Thromb. Haemostasis , vol.77 , pp. 221-222
    • Rance, A.1    Emmerich, J.2    Fiessinger, J.N.3
  • 298
    • 0030924102 scopus 로고    scopus 로고
    • A retrospective review of 61 patients with antiphospholipid syndrome: analysis of factors influencing recurrent thrombosis
    • Krnic-Barrie, S., O'Connor, C.R., Looney, S.W., Pierangeli, S.S., Harris, E.N., A retrospective review of 61 patients with antiphospholipid syndrome: analysis of factors influencing recurrent thrombosis. Arch. Intern. Med. 157 (1997), 2101–2108.
    • (1997) Arch. Intern. Med. , vol.157 , pp. 2101-2108
    • Krnic-Barrie, S.1    O'Connor, C.R.2    Looney, S.W.3    Pierangeli, S.S.4    Harris, E.N.5
  • 299
    • 0037182043 scopus 로고    scopus 로고
    • Bleeding and recurrent thrombosis in definite antiphospholipid syndrome: analysis of a series of 66 patients treated with oral anticoagulation to a target international normalized ratio of 3.5
    • Ruiz-Irastorza, G., Khamashta, M.A., Hunt, B.J., Escudero, A., Cuadrado, M.J., Hughes, G.R., Bleeding and recurrent thrombosis in definite antiphospholipid syndrome: analysis of a series of 66 patients treated with oral anticoagulation to a target international normalized ratio of 3.5. Arch. Intern. Med. 162 (2002), 1164–1169.
    • (2002) Arch. Intern. Med. , vol.162 , pp. 1164-1169
    • Ruiz-Irastorza, G.1    Khamashta, M.A.2    Hunt, B.J.3    Escudero, A.4    Cuadrado, M.J.5    Hughes, G.R.6
  • 300
    • 33747102710 scopus 로고    scopus 로고
    • Warfarin-related outcomes in patients with antiphospholipid antibody syndrome managed in an anticoagulation clinic
    • Wittkowsky, A.K., Downing, J., Blackburn, J., Nutescu, E., Warfarin-related outcomes in patients with antiphospholipid antibody syndrome managed in an anticoagulation clinic. Thromb. Haemostasis 96 (2006), 137–141.
    • (2006) Thromb. Haemostasis , vol.96 , pp. 137-141
    • Wittkowsky, A.K.1    Downing, J.2    Blackburn, J.3    Nutescu, E.4
  • 301
    • 76149086177 scopus 로고    scopus 로고
    • Comparison between single antiplatelet therapy and combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndrome
    • Okuma, H., Kitagawa, Y., Yasuda, T., Tokuoka, K., Takagi, S., Comparison between single antiplatelet therapy and combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndrome. Int. J. Med. Sci. 7 (2010), 15–18.
    • (2010) Int. J. Med. Sci. , vol.7 , pp. 15-18
    • Okuma, H.1    Kitagawa, Y.2    Yasuda, T.3    Tokuoka, K.4    Takagi, S.5
  • 302
    • 0029970670 scopus 로고    scopus 로고
    • A clinical trial for the treatment of antiphospholipid antibody-associated recurrent pregnancy loss with lower dose heparin and aspirin
    • Kutteh, W.H., Ermel, L.D., A clinical trial for the treatment of antiphospholipid antibody-associated recurrent pregnancy loss with lower dose heparin and aspirin. Am. J. Reprod. Immunol. 35 (1996), 402–407.
    • (1996) Am. J. Reprod. Immunol. , vol.35 , pp. 402-407
    • Kutteh, W.H.1    Ermel, L.D.2
  • 303
    • 0031022366 scopus 로고    scopus 로고
    • Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies)
    • Rai, R., Cohen, H., Dave, M., Regan, L., Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies). Br. Med. J. 314 (1997), 253–257.
    • (1997) Br. Med. J. , vol.314 , pp. 253-257
    • Rai, R.1    Cohen, H.2    Dave, M.3    Regan, L.4
  • 304
    • 64849104901 scopus 로고    scopus 로고
    • Low molecular weight heparin and aspirin for recurrent pregnancy loss: results from the randomized, controlled HepASA trial
    • Laskin, C.A., Spitzer, K.A., Clark, C.A., Crowther, M.R., Ginsberg, J.S., et al. Low molecular weight heparin and aspirin for recurrent pregnancy loss: results from the randomized, controlled HepASA trial. J. Rheumatol. 36 (2009), 279–287.
    • (2009) J. Rheumatol. , vol.36 , pp. 279-287
    • Laskin, C.A.1    Spitzer, K.A.2    Clark, C.A.3    Crowther, M.R.4    Ginsberg, J.S.5
  • 307
    • 27744565638 scopus 로고    scopus 로고
    • Comparison of two therapeutic protocols in patients with antiphospholipid antibodies and recurrent miscarriages
    • Jeremić K., Pervulov, M., Gojnić M., Dukanac, J., Ljubić A., Stojnić J., Comparison of two therapeutic protocols in patients with antiphospholipid antibodies and recurrent miscarriages. Vojnosanit. Pregl. 62 (2005), 435–439.
    • (2005) Vojnosanit. Pregl. , vol.62 , pp. 435-439
    • Jeremić, K.1    Pervulov, M.2    Gojnić, M.3    Dukanac, J.4    Ljubić, A.5    Stojnić, J.6
  • 308
    • 84869414418 scopus 로고    scopus 로고
    • Effect of prednisone, aspirin, low molecular weight heparin and intravenous immunoglobulin on outcome of pregnancy in women with antiphospholipid syndrome
    • Xiao, J., Xiong, J., Zhu, F., He, L., Effect of prednisone, aspirin, low molecular weight heparin and intravenous immunoglobulin on outcome of pregnancy in women with antiphospholipid syndrome. Exp. Ther. Med. 5 (2013), 287–291.
    • (2013) Exp. Ther. Med. , vol.5 , pp. 287-291
    • Xiao, J.1    Xiong, J.2    Zhu, F.3    He, L.4
  • 309
    • 0036045796 scopus 로고    scopus 로고
    • A cross-sectional study of clinical thrombotic risk factors and preventive treatments in antiphospholipid syndrome
    • Erkan, D., Yazici, Y., Peterson, M.G., Sammaritano, L., Lockshin, M.D., A cross-sectional study of clinical thrombotic risk factors and preventive treatments in antiphospholipid syndrome. Rheumatology 41 (2002), 924–929.
    • (2002) Rheumatology , vol.41 , pp. 924-929
    • Erkan, D.1    Yazici, Y.2    Peterson, M.G.3    Sammaritano, L.4    Lockshin, M.D.5
  • 310
    • 17144382450 scopus 로고    scopus 로고
    • Antiphospholipid antibody profiles and their clinical associations in Chinese patients with systemic lupus erythematosus
    • Mok, M.Y., Chan, E.Y.T., Fong, D.Y.T., Leung, K.F.S., Wong, W.S., Lau, C.S., Antiphospholipid antibody profiles and their clinical associations in Chinese patients with systemic lupus erythematosus. J. Rheumatol. 32 (2005), 622–628.
    • (2005) J. Rheumatol. , vol.32 , pp. 622-628
    • Mok, M.Y.1    Chan, E.Y.T.2    Fong, D.Y.T.3    Leung, K.F.S.4    Wong, W.S.5    Lau, C.S.6
  • 311
    • 41749083256 scopus 로고    scopus 로고
    • Influence of aspirin on the clinical outcomes of 103 anti-phospholipid antibodies-positive patients
    • Hereng, T., Lambert, M., Hachulla, E., Samor, M., Dubucquoi, S., Caron, C., et al. Influence of aspirin on the clinical outcomes of 103 anti-phospholipid antibodies-positive patients. Lupus 17 (2008), 11–15.
    • (2008) Lupus , vol.17 , pp. 11-15
    • Hereng, T.1    Lambert, M.2    Hachulla, E.3    Samor, M.4    Dubucquoi, S.5    Caron, C.6
  • 312
    • 33846616931 scopus 로고    scopus 로고
    • Analysis of risk factors for the development of thrombotic complications in antiphospholipid antibody positive lupus patients
    • Tarr, T., Lakos, G., Bhattoa, H.P., Shoenfeld, Y., Szegedi, G., Kiss, E., Analysis of risk factors for the development of thrombotic complications in antiphospholipid antibody positive lupus patients. Lupus 16 (2007), 39–45.
    • (2007) Lupus , vol.16 , pp. 39-45
    • Tarr, T.1    Lakos, G.2    Bhattoa, H.P.3    Shoenfeld, Y.4    Szegedi, G.5    Kiss, E.6
  • 313
    • 79955815184 scopus 로고    scopus 로고
    • Risk factors for a first thrombotic event in antiphospholipid antibody carriers: a prospective multicentre follow-up study
    • Ruffatti, A., del Ross, T., Ciprian, M., Bertero, M.T., Sciascia, S., Salvatore, S., et al. Risk factors for a first thrombotic event in antiphospholipid antibody carriers: a prospective multicentre follow-up study. Ann. Rheum. Dis. 70 (2011), 1083–1086.
    • (2011) Ann. Rheum. Dis. , vol.70 , pp. 1083-1086
    • Ruffatti, A.1    del Ross, T.2    Ciprian, M.3    Bertero, M.T.4    Sciascia, S.5    Salvatore, S.6
  • 314
    • 80055066032 scopus 로고    scopus 로고
    • Incidence of a first thromboembolic event in asymptomatic carriers of high-risk antiphospholipid antibody profile: a multicenter prospective study
    • Pengo, V., Ruffatti, A., Legnani, C., Testa, S., Fierro, T., Marongiu, F., et al. Incidence of a first thromboembolic event in asymptomatic carriers of high-risk antiphospholipid antibody profile: a multicenter prospective study. Blood 118 (2011), 4714–4718.
    • (2011) Blood , vol.118 , pp. 4714-4718
    • Pengo, V.1    Ruffatti, A.2    Legnani, C.3    Testa, S.4    Fierro, T.5    Marongiu, F.6
  • 315
    • 84911192214 scopus 로고    scopus 로고
    • Persistent antiphospholipid antibody (aPL) in asymptomatic carriers as a risk factor for future thrombotic events: a nationwide prospective study
    • Mustonen, P., Lehtonen, K.V., Javela, K., Puurunen, M., Persistent antiphospholipid antibody (aPL) in asymptomatic carriers as a risk factor for future thrombotic events: a nationwide prospective study. Lupus 23 (2014), 1468–1476.
    • (2014) Lupus , vol.23 , pp. 1468-1476
    • Mustonen, P.1    Lehtonen, K.V.2    Javela, K.3    Puurunen, M.4
  • 316
    • 84922552998 scopus 로고    scopus 로고
    • Incidence of a first thromboembolic event in carriers of isolated lupus anticoagulant
    • Pengo, V., Testa, S., Martinelli, I., Ghirarduzzi, A., Legnani, C., Gresele, P., Incidence of a first thromboembolic event in carriers of isolated lupus anticoagulant. Thromb. Res. 135 (2015), 46–49.
    • (2015) Thromb. Res. , vol.135 , pp. 46-49
    • Pengo, V.1    Testa, S.2    Martinelli, I.3    Ghirarduzzi, A.4    Legnani, C.5    Gresele, P.6
  • 317
    • 85046590281 scopus 로고    scopus 로고
    • Beyond thrombosis: anti-β2GPI domain 1 antibodies identify late pregnancy morbidity in anti-phospholipid syndrome. J. Autoimmun. This issue.
    • Chighizola CB, Pregnolato F, Andreoli L, et al. Beyond thrombosis: anti-β2GPI domain 1 antibodies identify late pregnancy morbidity in anti-phospholipid syndrome. J. Autoimmun. This issue.
    • Chighizola, C.B.1    Pregnolato, F.2    Andreoli, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.