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Volumn 16, Issue 2, 2014, Pages

Antiphospholipid syndrome in 2014: More clinical manifestations, novel pathogenic players and emerging biomarkers

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; BETA2 GLYCOPROTEIN 1 ANTIBODY; BIOLOGICAL MARKER; CARDIOLIPIN ANTIBODY; LIPOCORTIN 2; LIPOCORTIN 5; PHOSPHATIDYLETHANOLAMINE ANTIBODY; PHOSPHOLIPID ANTIBODY; PROTEIN ANTIBODY; PROTHROMBIN ANTIBODY; UNCLASSIFIED DRUG; VIMENTIN ANTIBODY;

EID: 84899102723     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar4549     Document Type: Review
Times cited : (93)

References (90)
  • 3
    • 84861342502 scopus 로고    scopus 로고
    • Update on the catastrophic antiphospholipid syndrome and the 'CAPS Registry'
    • Cervera R, Espinosa G. Update on the catastrophic antiphospholipid syndrome and the 'CAPS Registry'. Semin Thromb Hemost 2012, 38:333-338.
    • (2012) Semin Thromb Hemost , vol.38 , pp. 333-338
    • Cervera, R.1    Espinosa, G.2
  • 4
    • 69549110747 scopus 로고    scopus 로고
    • Antiphospholipid syndrome and systemic lupus erythematosus: are they separate entities or just clinical presentations on the same scale?
    • 10.1097/BOR.0b013e32832effdd, 19593144
    • Shoenfeld Y, Meroni PL, Toubi E. Antiphospholipid syndrome and systemic lupus erythematosus: are they separate entities or just clinical presentations on the same scale?. Curr Opin Rheumatol 2009, 21:495-500. 10.1097/BOR.0b013e32832effdd, 19593144.
    • (2009) Curr Opin Rheumatol , vol.21 , pp. 495-500
    • Shoenfeld, Y.1    Meroni, P.L.2    Toubi, E.3
  • 5
    • 77951209375 scopus 로고    scopus 로고
    • Non-criteria manifestations of antiphospholipid syndrome
    • 10.1177/0961203309360545, 20353981
    • Erkan D, Lockshin MD. Non-criteria manifestations of antiphospholipid syndrome. Lupus 2010, 19:424-427. 10.1177/0961203309360545, 20353981.
    • (2010) Lupus , vol.19 , pp. 424-427
    • Erkan, D.1    Lockshin, M.D.2
  • 6
    • 23844440880 scopus 로고    scopus 로고
    • Antiphospholipid antibody associated thrombocytopenia and the paradoxical risk of thrombosis
    • 10.1191/0961203305lu2145rr, 16130503
    • Atsumi T, Furukawa S, Amengual O, Koike T. Antiphospholipid antibody associated thrombocytopenia and the paradoxical risk of thrombosis. Lupus 2005, 14:499-504. 10.1191/0961203305lu2145rr, 16130503.
    • (2005) Lupus , vol.14 , pp. 499-504
    • Atsumi, T.1    Furukawa, S.2    Amengual, O.3    Koike, T.4
  • 7
    • 77955544103 scopus 로고    scopus 로고
    • Dermatological manifestations of Hughes' antiphospholipid antibody syndrome
    • 10.1177/0961203310370343, 20693200
    • Frances C. Dermatological manifestations of Hughes' antiphospholipid antibody syndrome. Lupus 2010, 19:1071-1077. 10.1177/0961203310370343, 20693200.
    • (2010) Lupus , vol.19 , pp. 1071-1077
    • Frances, C.1
  • 9
    • 66349127704 scopus 로고    scopus 로고
    • Renal involvement in the antiphospholipid syndrome (APS)-APS nephropathy
    • 10.1007/s12016-008-8112-z, 19048414
    • Tektonidou MG. Renal involvement in the antiphospholipid syndrome (APS)-APS nephropathy. Clin Rev Allergy Immunol 2009, 36:131-140. 10.1007/s12016-008-8112-z, 19048414.
    • (2009) Clin Rev Allergy Immunol , vol.36 , pp. 131-140
    • Tektonidou, M.G.1
  • 10
    • 79953302178 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and the brain: a consensus report
    • 10.1177/0961203310396748, 21303831
    • Brey RL, Muscal E, Chapman J. Antiphospholipid antibodies and the brain: a consensus report. Lupus 2011, 20:153-157. 10.1177/0961203310396748, 21303831.
    • (2011) Lupus , vol.20 , pp. 153-157
    • Brey, R.L.1    Muscal, E.2    Chapman, J.3
  • 12
    • 33751021370 scopus 로고    scopus 로고
    • Cognitive deficits in patients with antiphopholipid syndrome
    • 10.1001/archinte.166.20.2278, 17101948
    • Tektonidou MG, Varsou N, Kotoulas G, Antoniou A, Moutsopoulos HM. Cognitive deficits in patients with antiphopholipid syndrome. Arch Intern Med 2006, 166:2278-2284. 10.1001/archinte.166.20.2278, 17101948.
    • (2006) Arch Intern Med , vol.166 , pp. 2278-2284
    • Tektonidou, M.G.1    Varsou, N.2    Kotoulas, G.3    Antoniou, A.4    Moutsopoulos, H.M.5
  • 16
    • 79958086576 scopus 로고    scopus 로고
    • Pathogenesis of antiphospholipid syndrome: understanding the antibodies
    • Meroni PL, Borghi MO, Raschi E, Tedesco F. Pathogenesis of antiphospholipid syndrome: understanding the antibodies. Nat Rev Rheum 2011, 7:330-339.
    • (2011) Nat Rev Rheum , vol.7 , pp. 330-339
    • Meroni, P.L.1    Borghi, M.O.2    Raschi, E.3    Tedesco, F.4
  • 17
    • 84878619290 scopus 로고    scopus 로고
    • Correct laboratory approach to APS diagnosis and monitoring
    • 10.1016/j.autrev.2012.11.008, 23219767
    • Pengo V, Banzato A, Denas G, Jose SP, Bison E, Hoxha A, Ruffatti A. Correct laboratory approach to APS diagnosis and monitoring. Autoimmun Rev 2013, 12:832-834. 10.1016/j.autrev.2012.11.008, 23219767.
    • (2013) Autoimmun Rev , vol.12 , pp. 832-834
    • Pengo, V.1    Banzato, A.2    Denas, G.3    Jose, S.P.4    Bison, E.5    Hoxha, A.6    Ruffatti, A.7
  • 18
    • 7044223470 scopus 로고    scopus 로고
    • B2-glycoprotein I dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome
    • 10.1182/blood-2004-03-1107, 15315975
    • De Laat HB, Derksen RHWM, Urbanus RT, Roest M, de Groot PG. B2-glycoprotein I dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome. Blood 2004, 104:3598-3602. 10.1182/blood-2004-03-1107, 15315975.
    • (2004) Blood , vol.104 , pp. 3598-3602
    • De Laat, H.B.1    Derksen, R.H.W.M.2    Urbanus, R.T.3    Roest, M.4    de Groot, P.G.5
  • 20
    • 84856371421 scopus 로고    scopus 로고
    • Efficacy of the antiphospholipid score for the diagnosis of antiphospholipid syndrome and its predictive value for thrombotic events
    • 10.1002/art.33340, 21953404
    • Otomo K, Atsumi T, Amengual O, Fujieda Y, Kato M, Oku K, Horita T, Yasuda S, Koike T. Efficacy of the antiphospholipid score for the diagnosis of antiphospholipid syndrome and its predictive value for thrombotic events. Arthritis Rheum 2012, 64:504-512. 10.1002/art.33340, 21953404.
    • (2012) Arthritis Rheum , vol.64 , pp. 504-512
    • Otomo, K.1    Atsumi, T.2    Amengual, O.3    Fujieda, Y.4    Kato, M.5    Oku, K.6    Horita, T.7    Yasuda, S.8    Koike, T.9
  • 21
    • 84867021897 scopus 로고    scopus 로고
    • Antiphospholipid antibodies: evaluation of the thrombotic risk
    • Devreese KM. Antiphospholipid antibodies: evaluation of the thrombotic risk. Thrombosis Res 2012, 130:S37-S40.
    • (2012) Thrombosis Res , vol.130
    • Devreese, K.M.1
  • 22
    • 84872399169 scopus 로고    scopus 로고
    • The clinical relevance of IgA anticardiolipin and IgA anti-β2 glycoprotein I antiphospholipid antibodies. A systematic review
    • 10.1016/j.autrev.2012.08.002, 22951216
    • Meijide H, Sciascia S, Sanna G, Khamashta MA, Bertolaccini ML. The clinical relevance of IgA anticardiolipin and IgA anti-β2 glycoprotein I antiphospholipid antibodies. A systematic review. Autoimmun Rev 2013, 12:421-425. 10.1016/j.autrev.2012.08.002, 22951216.
    • (2013) Autoimmun Rev , vol.12 , pp. 421-425
    • Meijide, H.1    Sciascia, S.2    Sanna, G.3    Khamashta, M.A.4    Bertolaccini, M.L.5
  • 24
    • 84871552087 scopus 로고    scopus 로고
    • Diagnosis of antiphospholipid syndrome in routine clinical practice
    • 10.1177/0961203312460722, 22988029
    • Gardiner C, Hills J, Machin SJ, Cohen H. Diagnosis of antiphospholipid syndrome in routine clinical practice. Lupus 2013, 22:18-25. 10.1177/0961203312460722, 22988029.
    • (2013) Lupus , vol.22 , pp. 18-25
    • Gardiner, C.1    Hills, J.2    Machin, S.J.3    Cohen, H.4
  • 25
    • 84902047745 scopus 로고    scopus 로고
    • Phospholipid autoantibodies (non-anticardiolipin)-anti-prothrombin antibodies
    • New York: Elsevier, Shoenfeld Y, Gershwin E, Meroni PL, 3
    • Pregnolato F, Chighizola C. Phospholipid autoantibodies (non-anticardiolipin)-anti-prothrombin antibodies. The Autoantibodies 2014, 741-749. New York: Elsevier, Shoenfeld Y, Gershwin E, Meroni PL, 3.
    • (2014) The Autoantibodies , pp. 741-749
    • Pregnolato, F.1    Chighizola, C.2
  • 27
    • 84893175081 scopus 로고    scopus 로고
    • Anti-prothrombin (aPT) and anti-phosphatidylserine/prothrombin (aPS/PT) antibodies and the risk of thrombosis in the antiphospholipid syndrome: a systematic review
    • Sciascia S, Sanna G, Murru V, Roccatello D, Khamashta M, Bertolaccini ML. Anti-prothrombin (aPT) and anti-phosphatidylserine/prothrombin (aPS/PT) antibodies and the risk of thrombosis in the antiphospholipid syndrome: a systematic review. Thromb Haemost 2014, 111:354-364.
    • (2014) Thromb Haemost , vol.111 , pp. 354-364
    • Sciascia, S.1    Sanna, G.2    Murru, V.3    Roccatello, D.4    Khamashta, M.5    Bertolaccini, M.L.6
  • 28
    • 0023772539 scopus 로고
    • Anti-prothrombin antibodies and the lupus anticoagulant
    • Fleck RA, Rapaport SI, Rao LVM. Anti-prothrombin antibodies and the lupus anticoagulant. Blood 1988, 72:512-519.
    • (1988) Blood , vol.72 , pp. 512-519
    • Fleck, R.A.1    Rapaport, S.I.2    Rao, L.V.M.3
  • 29
    • 0029896410 scopus 로고    scopus 로고
    • Autoantibodies to phospholipid-binding plasma proteins in patients with thrombosis and phospholipid-reactive antibodies
    • Pengo V, Biasiolo A, Brocco T, Tonetto S, Ruffatti A. Autoantibodies to phospholipid-binding plasma proteins in patients with thrombosis and phospholipid-reactive antibodies. Thromb Haemost 1996, 75:721-724.
    • (1996) Thromb Haemost , vol.75 , pp. 721-724
    • Pengo, V.1    Biasiolo, A.2    Brocco, T.3    Tonetto, S.4    Ruffatti, A.5
  • 30
    • 0030457493 scopus 로고    scopus 로고
    • Lupus anticoagulant is the strongest risk factor for both venous and arterial thrombosis in patients with systemic lupus erythematosus. Comparison between different assays for the detection of antiphospholipid antibodies
    • Horback DA, van Oort E, Donders RC, Derksen RH, de Groot PG. Lupus anticoagulant is the strongest risk factor for both venous and arterial thrombosis in patients with systemic lupus erythematosus. Comparison between different assays for the detection of antiphospholipid antibodies. Thromb Haemost 1996, 76:916-924.
    • (1996) Thromb Haemost , vol.76 , pp. 916-924
    • Horback, D.A.1    van Oort, E.2    Donders, R.C.3    Derksen, R.H.4    de Groot, P.G.5
  • 31
    • 0030199628 scopus 로고    scopus 로고
    • Antibodies to phospholipid-binding plasma proteins and occurrence of thrombosis in patients with systemic lupus erythematosus
    • 10.1006/clin.1996.0089, 8674235
    • Puurunen M, Vaarala O, Julkunen H, Aho K, Palosuo T. Antibodies to phospholipid-binding plasma proteins and occurrence of thrombosis in patients with systemic lupus erythematosus. Clin Immunol Immunopathol 1996, 80:16-22. 10.1006/clin.1996.0089, 8674235.
    • (1996) Clin Immunol Immunopathol , vol.80 , pp. 16-22
    • Puurunen, M.1    Vaarala, O.2    Julkunen, H.3    Aho, K.4    Palosuo, T.5
  • 32
    • 0030826383 scopus 로고    scopus 로고
    • Anti-cardiolipin, antibeta2glycoprotein I, antiprothrombin antibodies, and lupus anticoagulant in patients with systemic lupus erythematosus with a history of thrombosis
    • Swadzba J, De Clerck LS, Stevens WJ, Bridts CH, van Cotthem KA, Musial J, Jankowski M, Szczeklik A. Anti-cardiolipin, antibeta2glycoprotein I, antiprothrombin antibodies, and lupus anticoagulant in patients with systemic lupus erythematosus with a history of thrombosis. J Rheumatol 1997, 24:1710-1715.
    • (1997) J Rheumatol , vol.24 , pp. 1710-1715
    • Swadzba, J.1    De Clerck, L.S.2    Stevens, W.J.3    Bridts, C.H.4    van Cotthem, K.A.5    Musial, J.6    Jankowski, M.7    Szczeklik, A.8
  • 33
    • 0030937274 scopus 로고    scopus 로고
    • Different anticoagulant and immunological properties of anti-prothrombin antibodies in patients with antiphospholipid antibodies
    • Galli M, Beretta G, Daldossi M, Bevers EM, Barbui T. Different anticoagulant and immunological properties of anti-prothrombin antibodies in patients with antiphospholipid antibodies. Thromb Haemost 1997, 77:486-491.
    • (1997) Thromb Haemost , vol.77 , pp. 486-491
    • Galli, M.1    Beretta, G.2    Daldossi, M.3    Bevers, E.M.4    Barbui, T.5
  • 34
    • 0031876557 scopus 로고    scopus 로고
    • Autoantibodies to human prothrombin and clinical manifestations in 207 patients with systemic lupus erythematosus
    • Bertolaccini ML, Atsumi T, Khamashta MA, Amengual O, Hughes GR. Autoantibodies to human prothrombin and clinical manifestations in 207 patients with systemic lupus erythematosus. J Rheumatol 1998, 25:1104-1108.
    • (1998) J Rheumatol , vol.25 , pp. 1104-1108
    • Bertolaccini, M.L.1    Atsumi, T.2    Khamashta, M.A.3    Amengual, O.4    Hughes, G.R.5
  • 35
    • 0033486182 scopus 로고    scopus 로고
    • Occurrence of anti-prothrombin antibodies and anti-beta2glycoprotein I antibodies in patients with a history of thrombosis
    • 10.1016/S0022-2143(99)90101-4, 10595789
    • Forastiero R, Martinuzzo ME, Adamczuk Y, Carreras LO. Occurrence of anti-prothrombin antibodies and anti-beta2glycoprotein I antibodies in patients with a history of thrombosis. J Lab Clin Med 1999, 134:610-615. 10.1016/S0022-2143(99)90101-4, 10595789.
    • (1999) J Lab Clin Med , vol.134 , pp. 610-615
    • Forastiero, R.1    Martinuzzo, M.E.2    Adamczuk, Y.3    Carreras, L.O.4
  • 37
    • 0033711669 scopus 로고    scopus 로고
    • Association of autoantibodies against the phosphatidylserine-prothrobin complex with manifestations of the antiphospholipid syndrome and in the presence of lupus anticoagulant
    • 10.1002/1529-0131(200009)43:9<1982::AID-ANR9>3.0.CO;2-2, 11014348
    • Atsumi T, Ieko M, Bertolaccini ML, Ichikawa K, Tsutsumi A, Matsuura E, Koike T. Association of autoantibodies against the phosphatidylserine-prothrobin complex with manifestations of the antiphospholipid syndrome and in the presence of lupus anticoagulant. Arthritis Rheum 2000, 43:1982-1993. 10.1002/1529-0131(200009)43:9<1982::AID-ANR9>3.0.CO;2-2, 11014348.
    • (2000) Arthritis Rheum , vol.43 , pp. 1982-1993
    • Atsumi, T.1    Ieko, M.2    Bertolaccini, M.L.3    Ichikawa, K.4    Tsutsumi, A.5    Matsuura, E.6    Koike, T.7
  • 38
    • 0034528912 scopus 로고    scopus 로고
    • Lupus anticoagulants and thrombosis: clinical association of different coagulation and immunologic tests
    • Galli M, Dlott J, Norbis F, Ruggeri L, Cler L, Triplett DA, Barbui T. Lupus anticoagulants and thrombosis: clinical association of different coagulation and immunologic tests. Thromb Haemost 2000, 84:1012-1016.
    • (2000) Thromb Haemost , vol.84 , pp. 1012-1016
    • Galli, M.1    Dlott, J.2    Norbis, F.3    Ruggeri, L.4    Cler, L.5    Triplett, D.A.6    Barbui, T.7
  • 39
    • 0034791684 scopus 로고    scopus 로고
    • Anti-prothrombin antibodies combined with lupus anticoagulant activity is an essential risk factor for venous thromboembolism in patients with systemic lupus erythematosus
    • 10.1046/j.1365-2141.2001.02950.x, 11552993
    • Nojima H, Kuratsune H, Suehisa E, Futsukaichi Y, Yamanishi H, Machii T, Kitani T, Iwatani Y, Kanakura Y. Anti-prothrombin antibodies combined with lupus anticoagulant activity is an essential risk factor for venous thromboembolism in patients with systemic lupus erythematosus. Br J Haematol 2001, 114:647-654. 10.1046/j.1365-2141.2001.02950.x, 11552993.
    • (2001) Br J Haematol , vol.114 , pp. 647-654
    • Nojima, H.1    Kuratsune, H.2    Suehisa, E.3    Futsukaichi, Y.4    Yamanishi, H.5    Machii, T.6    Kitani, T.7    Iwatani, Y.8    Kanakura, Y.9
  • 40
    • 0035001425 scopus 로고    scopus 로고
    • Association between the prevalence of antibodies to beta(2)-glycoprotein I, prothrombin, protein C, protein S, and annexin V in patients with systemic lupus erythematosus and thrombotic and thrombocytopenic complications
    • Nojima J, Kuratsune H, Suehisa E, Futsukaichi Y, Yamanishi H, Machii T, Iwatani Y, Kanakura Y. Association between the prevalence of antibodies to beta(2)-glycoprotein I, prothrombin, protein C, protein S, and annexin V in patients with systemic lupus erythematosus and thrombotic and thrombocytopenic complications. Clin Chem 2001, 47:1008-1015.
    • (2001) Clin Chem , vol.47 , pp. 1008-1015
    • Nojima, J.1    Kuratsune, H.2    Suehisa, E.3    Futsukaichi, Y.4    Yamanishi, H.5    Machii, T.6    Iwatani, Y.7    Kanakura, Y.8
  • 41
    • 0142259265 scopus 로고    scopus 로고
    • A study on associations between antiprothrombin antibodies, antiplasminogen antibodies and thrombosis
    • Simmelink MJA, De Groot PG, Derksen RHWM. A study on associations between antiprothrombin antibodies, antiplasminogen antibodies and thrombosis. J Thromb Haemost 2002, 1:735-739.
    • (2002) J Thromb Haemost , vol.1 , pp. 735-739
    • Simmelink, M.J.A.1    De Groot, P.G.2    Derksen, R.H.W.M.3
  • 42
    • 0036792287 scopus 로고    scopus 로고
    • Antiprothrombin antibodies in patients with systemic lupus erythematosus or with primary antiphospholipid syndrome
    • 10.1097/00124743-200210000-00004, 17041380
    • Salcido-Ochoa F, Cabiedes J, Alarcón-Segovia D, Cabral AR. Antiprothrombin antibodies in patients with systemic lupus erythematosus or with primary antiphospholipid syndrome. J Clin Rheumatol 2002, 8:251-255. 10.1097/00124743-200210000-00004, 17041380.
    • (2002) J Clin Rheumatol , vol.8 , pp. 251-255
    • Salcido-Ochoa, F.1    Cabiedes, J.2    Alarcón-Segovia, D.3    Cabral, A.R.4
  • 44
    • 0037384880 scopus 로고    scopus 로고
    • Clinical significance of antiphospholipid protein antibodies. Receiver operating characteristics plot analysis
    • Musial J, Swadzba J, Motyl A, Iwaniec T. Clinical significance of antiphospholipid protein antibodies. Receiver operating characteristics plot analysis. J Rheumatol 2003, 30:723-730.
    • (2003) J Rheumatol , vol.30 , pp. 723-730
    • Musial, J.1    Swadzba, J.2    Motyl, A.3    Iwaniec, T.4
  • 46
    • 4444273530 scopus 로고    scopus 로고
    • The association of antibodies to cardiolipin, beta 2-glycoprotein I, prothrombin, and oxidized low-density lipoprotein with thrombosis in 292 patients with familial and sporadic systemic lupus erythematosus
    • 10.1080/03009740410005386, 15370721
    • Koskenmies S, Vaarala O, Widen E, Kere J, Palosuo T, Julkunen H. The association of antibodies to cardiolipin, beta 2-glycoprotein I, prothrombin, and oxidized low-density lipoprotein with thrombosis in 292 patients with familial and sporadic systemic lupus erythematosus. Scand J Rheumatol 2004, 33:246-252. 10.1080/03009740410005386, 15370721.
    • (2004) Scand J Rheumatol , vol.33 , pp. 246-252
    • Koskenmies, S.1    Vaarala, O.2    Widen, E.3    Kere, J.4    Palosuo, T.5    Julkunen, H.6
  • 47
    • 13844267691 scopus 로고    scopus 로고
    • Antiprothrombin antibodies detected in two different assay systems. Prevalence and clinical significance in systemic lupus erythematosus
    • Bertolaccini ML, Atsumi T, Koike T, Hughes GR, Khamashta MA. Antiprothrombin antibodies detected in two different assay systems. Prevalence and clinical significance in systemic lupus erythematosus. Thromb Haemost 2005, 93:289-297.
    • (2005) Thromb Haemost , vol.93 , pp. 289-297
    • Bertolaccini, M.L.1    Atsumi, T.2    Koike, T.3    Hughes, G.R.4    Khamashta, M.A.5
  • 48
    • 11844251124 scopus 로고    scopus 로고
    • Prevalence and clinical correlation of anti-phospholipid binding protein antibodies in anti-cardiolipin negative patients with systemic lupus erythematosus and women with unexplained recurrent miscarriages
    • Bizzaro N, Tonutti E, Villalta D, Tampoia M, Tozzoli R. Prevalence and clinical correlation of anti-phospholipid binding protein antibodies in anti-cardiolipin negative patients with systemic lupus erythematosus and women with unexplained recurrent miscarriages. Arch Pathol Lab Med 2005, 129:61-68.
    • (2005) Arch Pathol Lab Med , vol.129 , pp. 61-68
    • Bizzaro, N.1    Tonutti, E.2    Villalta, D.3    Tampoia, M.4    Tozzoli, R.5
  • 49
    • 24944552151 scopus 로고    scopus 로고
    • A prospective study of antibodies to beta2-glycoprotein I and prothrombin, and risk of thrombosis
    • 10.1111/j.1538-7836.2005.01295.x, 15946213
    • Forastiero R, Martinuzzo M, Pombo G, Puente D, Rossi A, Celebrin L, Bonaccorso S, Aversa L. A prospective study of antibodies to beta2-glycoprotein I and prothrombin, and risk of thrombosis. J Thromb Haemost 2005, 3:1231-1238. 10.1111/j.1538-7836.2005.01295.x, 15946213.
    • (2005) J Thromb Haemost , vol.3 , pp. 1231-1238
    • Forastiero, R.1    Martinuzzo, M.2    Pombo, G.3    Puente, D.4    Rossi, A.5    Celebrin, L.6    Bonaccorso, S.7    Aversa, L.8
  • 50
    • 32644464435 scopus 로고    scopus 로고
    • Prevalence and clinical correlates of anti-phospholipid antibodies in South Africans with systemic lupus erythematosus
    • 10.1080/03009740510026913, 16467038
    • Gould T, Tikly M, Asherson R, Loizou S, Singh S. Prevalence and clinical correlates of anti-phospholipid antibodies in South Africans with systemic lupus erythematosus. Scand J Rheumatol 2006, 35:29-34. 10.1080/03009740510026913, 16467038.
    • (2006) Scand J Rheumatol , vol.35 , pp. 29-34
    • Gould, T.1    Tikly, M.2    Asherson, R.3    Loizou, S.4    Singh, S.5
  • 51
    • 33745045915 scopus 로고    scopus 로고
    • Significance of anti-prothrombin antibodies in patients with systemic lupus erythematosus: clinical evaluation of the antiprothrombin assay and the anti-phosphatidylserine/prothrombin assay, and comparison with other antiphospholipid antibody assays
    • 10.3109/s10165-006-0481-7, 2778700, 16767554
    • Tsutumi A, Hayashi T, Chino Y, Mamura M, Goto D, Matsumoto I, Ito S, Sumida T. Significance of anti-prothrombin antibodies in patients with systemic lupus erythematosus: clinical evaluation of the antiprothrombin assay and the anti-phosphatidylserine/prothrombin assay, and comparison with other antiphospholipid antibody assays. Mod Rheumatol 2006, 16:158-164. 10.3109/s10165-006-0481-7, 2778700, 16767554.
    • (2006) Mod Rheumatol , vol.16 , pp. 158-164
    • Tsutumi, A.1    Hayashi, T.2    Chino, Y.3    Mamura, M.4    Goto, D.5    Matsumoto, I.6    Ito, S.7    Sumida, T.8
  • 52
    • 33744493101 scopus 로고    scopus 로고
    • The presence of anti-phosphatidylserine/prothrombin antibodies as risk factor for both arterial and venous thrombosis in patients with systemic lupus erythematosus
    • Nojima J, Iwatani Y, Suehisa E, Suehisa E, Kuratsune H, Kanakura Y. The presence of anti-phosphatidylserine/prothrombin antibodies as risk factor for both arterial and venous thrombosis in patients with systemic lupus erythematosus. Haematologica 2006, 91:699-702.
    • (2006) Haematologica , vol.91 , pp. 699-702
    • Nojima, J.1    Iwatani, Y.2    Suehisa, E.3    Suehisa, E.4    Kuratsune, H.5    Kanakura, Y.6
  • 53
    • 34250173118 scopus 로고    scopus 로고
    • Anti-prothrombin antibodies predict thrombosis in patients with systemic lupus erythematosus: a 15 year longitudinal study
    • 10.1111/j.1538-7836.2007.02532.x, 17388963
    • Bizzaro N, Ghirardello A, Zampieri S, Iaccarino L, Tozzoli R, Ruffatti A, Villalta D, Tonutti E, Doria A. Anti-prothrombin antibodies predict thrombosis in patients with systemic lupus erythematosus: a 15 year longitudinal study. J Thromb Haemost 2007, 5:1158-1164. 10.1111/j.1538-7836.2007.02532.x, 17388963.
    • (2007) J Thromb Haemost , vol.5 , pp. 1158-1164
    • Bizzaro, N.1    Ghirardello, A.2    Zampieri, S.3    Iaccarino, L.4    Tozzoli, R.5    Ruffatti, A.6    Villalta, D.7    Tonutti, E.8    Doria, A.9
  • 54
    • 34248582395 scopus 로고    scopus 로고
    • The clinical significance of anti-prothrombin antibodies for risk assessment of thromboembolism in patients with lupus anticoagulant
    • 10.1016/j.thromres.2007.01.001, 17328943
    • Sailer T, Vormittag R, Zoghlami C, Koder S, Quehenberger P, Male C, Pabinger I. The clinical significance of anti-prothrombin antibodies for risk assessment of thromboembolism in patients with lupus anticoagulant. Thromb Res 2007, 120:295-302. 10.1016/j.thromres.2007.01.001, 17328943.
    • (2007) Thromb Res , vol.120 , pp. 295-302
    • Sailer, T.1    Vormittag, R.2    Zoghlami, C.3    Koder, S.4    Quehenberger, P.5    Male, C.6    Pabinger, I.7
  • 55
    • 34547210670 scopus 로고    scopus 로고
    • Does the anti-prothrombin antibodies measurement provide additional information in patients with thrombosis?
    • 10.1016/j.imbio.2007.02.001, 17678713
    • Bardin N, Alessi MC, Dignat-George F, Vague IJ, Sampol J, Harlé JR, Sanmarco M. Does the anti-prothrombin antibodies measurement provide additional information in patients with thrombosis?. Immunobiology 2007, 212:557-565. 10.1016/j.imbio.2007.02.001, 17678713.
    • (2007) Immunobiology , vol.212 , pp. 557-565
    • Bardin, N.1    Alessi, M.C.2    Dignat-George, F.3    Vague, I.J.4    Sampol, J.5    Harlé, J.R.6    Sanmarco, M.7
  • 56
    • 70350568239 scopus 로고    scopus 로고
    • Autoantibodies against phosphatidylserine, prothrombin and phosphatidylserine-prothrombin complex: identical or distinct diagnostic tools for antiphospholipid syndrome?
    • 10.1016/j.cca.2009.09.006, 19751711
    • Jakowski TD, Wilson AR, Hill HR, Branch WD, Tebo AE. Autoantibodies against phosphatidylserine, prothrombin and phosphatidylserine-prothrombin complex: identical or distinct diagnostic tools for antiphospholipid syndrome?. Clin Chim Acta 2009, 410:19-24. 10.1016/j.cca.2009.09.006, 19751711.
    • (2009) Clin Chim Acta , vol.410 , pp. 19-24
    • Jakowski, T.D.1    Wilson, A.R.2    Hill, H.R.3    Branch, W.D.4    Tebo, A.E.5
  • 57
    • 70249093236 scopus 로고    scopus 로고
    • Identification of rare anti-phospholipid/protein co-factor autoantibodies in patients with systemic lupus erythematosus
    • 10.1080/08916930902882731, 19626489
    • Szodoray P, Tarr T, Tumpek J, Kappelmayer J, Lakos G, Poor G, Szegedi G, Kiss E. Identification of rare anti-phospholipid/protein co-factor autoantibodies in patients with systemic lupus erythematosus. Autoimmunity 2009, 42:497-506. 10.1080/08916930902882731, 19626489.
    • (2009) Autoimmunity , vol.42 , pp. 497-506
    • Szodoray, P.1    Tarr, T.2    Tumpek, J.3    Kappelmayer, J.4    Lakos, G.5    Poor, G.6    Szegedi, G.7    Kiss, E.8
  • 59
    • 80054030630 scopus 로고    scopus 로고
    • Anti-prothrombin antibodies are associated with adverse pregnancy outcome
    • 10.1111/j.1600-0897.2011.01031.x, 21682791
    • Marozio L, Curti A, Botta G, Canuto EM, Salton L, Tavella AM, Benedetto C. Anti-prothrombin antibodies are associated with adverse pregnancy outcome. Am J Reprod Immunol 2011, 66:404-409. 10.1111/j.1600-0897.2011.01031.x, 21682791.
    • (2011) Am J Reprod Immunol , vol.66 , pp. 404-409
    • Marozio, L.1    Curti, A.2    Botta, G.3    Canuto, E.M.4    Salton, L.5    Tavella, A.M.6    Benedetto, C.7
  • 60
    • 84858618879 scopus 로고    scopus 로고
    • The clinical significance of autoantibodies directed against prothrombin in primary antiphospholipid syndrome
    • 10.1016/j.cca.2012.02.004, 22349599
    • Hoxha A, Ruffatti A, Pittoni M. The clinical significance of autoantibodies directed against prothrombin in primary antiphospholipid syndrome. Clin Chim Acta 2012, 413:911-913. 10.1016/j.cca.2012.02.004, 22349599.
    • (2012) Clin Chim Acta , vol.413 , pp. 911-913
    • Hoxha, A.1    Ruffatti, A.2    Pittoni, M.3
  • 61
    • 84865016939 scopus 로고    scopus 로고
    • Anti-phosphatidylserine, anti-cardiolipin, anti-beta2glycoprotein I and anti-prothrombin antibodies in recurrent miscarriage at 8-12 gestational weeks
    • 10.1016/j.ejogrb.2012.04.001, 22555404
    • Sater MS, Finan RR, Abu-Hijleh FM, Abu-Hijleh TM, Almawi WY. Anti-phosphatidylserine, anti-cardiolipin, anti-beta2glycoprotein I and anti-prothrombin antibodies in recurrent miscarriage at 8-12 gestational weeks. Eur J Obstet Gynecol Reprod Biol 2012, 163:170-174. 10.1016/j.ejogrb.2012.04.001, 22555404.
    • (2012) Eur J Obstet Gynecol Reprod Biol , vol.163 , pp. 170-174
    • Sater, M.S.1    Finan, R.R.2    Abu-Hijleh, F.M.3    Abu-Hijleh, T.M.4    Almawi, W.Y.5
  • 62
    • 2442540021 scopus 로고    scopus 로고
    • Strong correlation between the prevalence of cerebral infarction and the presence of anti-cardiolipin/antibeta2-glycoprotein I and anti-phosphatidylserine/prothrombin antibodies. Co-existence of these antibodies enhance ADP-induced platelet activation
    • Nojima J, Kuratsune H, Suehisa E, Kitani T, Iwatani Y, Kanakura Y. Strong correlation between the prevalence of cerebral infarction and the presence of anti-cardiolipin/antibeta2-glycoprotein I and anti-phosphatidylserine/prothrombin antibodies. Co-existence of these antibodies enhance ADP-induced platelet activation. Thromb Haemost 2004, 91:967-976.
    • (2004) Thromb Haemost , vol.91 , pp. 967-976
    • Nojima, J.1    Kuratsune, H.2    Suehisa, E.3    Kitani, T.4    Iwatani, Y.5    Kanakura, Y.6
  • 63
    • 77951221087 scopus 로고    scopus 로고
    • Anti-prothrombin antibody: why do we need more assays?
    • 10.1177/0961203310361487, 20353984
    • Atsumi T, Koike T. Anti-prothrombin antibody: why do we need more assays?. Lupus 2010, 19:436-439. 10.1177/0961203310361487, 20353984.
    • (2010) Lupus , vol.19 , pp. 436-439
    • Atsumi, T.1    Koike, T.2
  • 64
    • 79958263734 scopus 로고    scopus 로고
    • Modified phosphatidylserine-dependent antithrombin ELISA enables identification of patients negative for other antiphospholipid antibodies and also detects low avidity antibodies
    • Žigon P, Ambrožič A, Čučnik S, Kveder T, Rozman B, Božič B. Modified phosphatidylserine-dependent antithrombin ELISA enables identification of patients negative for other antiphospholipid antibodies and also detects low avidity antibodies. Clin Chem Lab Med 2011, 49:1011-1018.
    • (2011) Clin Chem Lab Med , vol.49 , pp. 1011-1018
    • Žigon, P.1    Ambrožič, A.2    Čučnik, S.3    Kveder, T.4    Rozman, B.5    Božič, B.6
  • 66
    • 84871100111 scopus 로고    scopus 로고
    • Clinical accuracy for diagnosis of antiphospholipid syndrome in systemic lupus erythematosus: evaluation of 23 possible combinations of antiphospholipid antibody specificities
    • 10.1111/jth.12014, 23025466
    • Sciascia S, Murru V, Sanna G, Roccatello D, Khamashta MA, Bertolaccini ML. Clinical accuracy for diagnosis of antiphospholipid syndrome in systemic lupus erythematosus: evaluation of 23 possible combinations of antiphospholipid antibody specificities. J Thromb Haemost 2012, 10:2512-2518. 10.1111/jth.12014, 23025466.
    • (2012) J Thromb Haemost , vol.10 , pp. 2512-2518
    • Sciascia, S.1    Murru, V.2    Sanna, G.3    Roccatello, D.4    Khamashta, M.A.5    Bertolaccini, M.L.6
  • 68
    • 84870255310 scopus 로고    scopus 로고
    • Autoantibodies to domain 1 of beta 2 glycoprotein 1: a promising candidate biomarker for risk management in antiphospholipid syndrome
    • 10.1016/j.autrev.2012.05.006, 22652408
    • Mahler M, Norman GL, Meroni PL, Khamashta M. Autoantibodies to domain 1 of beta 2 glycoprotein 1: a promising candidate biomarker for risk management in antiphospholipid syndrome. Autoimmun Rev 2012, 12:313-317. 10.1016/j.autrev.2012.05.006, 22652408.
    • (2012) Autoimmun Rev , vol.12 , pp. 313-317
    • Mahler, M.1    Norman, G.L.2    Meroni, P.L.3    Khamashta, M.4
  • 69
    • 79551512120 scopus 로고    scopus 로고
    • Autoantibodies directed against domain I of beta2-glycoprotein I
    • 10.1007/s11926-010-0144-8, 3016149, 21046294
    • de Laat B, de Groot PG. Autoantibodies directed against domain I of beta2-glycoprotein I. Curr Rheumatol Rep 2011, 13:70-76. 10.1007/s11926-010-0144-8, 3016149, 21046294.
    • (2011) Curr Rheumatol Rep , vol.13 , pp. 70-76
    • de Laat, B.1    de Groot, P.G.2
  • 74
    • 84896702818 scopus 로고    scopus 로고
    • New tests to detect antiphospholipid antibodies: anti-domain I beta-2-glycoprotein-I antibodies
    • Chighizola CB, Gerosa M, Meroni PL. New tests to detect antiphospholipid antibodies: anti-domain I beta-2-glycoprotein-I antibodies. Curr Rheumatol Rep 2014, 16:402.
    • (2014) Curr Rheumatol Rep , vol.16 , pp. 402
    • Chighizola, C.B.1    Gerosa, M.2    Meroni, P.L.3
  • 76
    • 33846236309 scopus 로고    scopus 로고
    • Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: mutation studies including residues R39 to R43
    • 10.1002/art.22306, 2117024, 17195232
    • Ioannou Y, Pericleous C, Giles I, Latchman DS, Isenberg DA, Rahman A. Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: mutation studies including residues R39 to R43. Arthritis Rheum 2007, 56:280-290. 10.1002/art.22306, 2117024, 17195232.
    • (2007) Arthritis Rheum , vol.56 , pp. 280-290
    • Ioannou, Y.1    Pericleous, C.2    Giles, I.3    Latchman, D.S.4    Isenberg, D.A.5    Rahman, A.6
  • 77
    • 84899079153 scopus 로고    scopus 로고
    • A human monoclonal antibody against domain I of β2-glycoprotein I prevents clotting and fetal loss induced by polyclonal anti-phospholipid antibodies in animal models
    • Agostinis C, Durigutto P, Sblattero D, Borghi M, Grossi C, Bulla R, Macor P, Meroni PL, Tedesco F. A human monoclonal antibody against domain I of β2-glycoprotein I prevents clotting and fetal loss induced by polyclonal anti-phospholipid antibodies in animal models. Arthritis Rheum 2013, 65:S245.
    • (2013) Arthritis Rheum , vol.65
    • Agostinis, C.1    Durigutto, P.2    Sblattero, D.3    Borghi, M.4    Grossi, C.5    Bulla, R.6    Macor, P.7    Meroni, P.L.8    Tedesco, F.9
  • 78
    • 84870251694 scopus 로고    scopus 로고
    • Anti-phosphatidylethanolamine antibody, thromboembolic events and the antiphospholipid syndrome
    • 10.1016/j.autrev.2012.07.008, 22796282
    • Staub HL, Bertolaccini ML, Khamashta MA. Anti-phosphatidylethanolamine antibody, thromboembolic events and the antiphospholipid syndrome. Autoimmun Rev 2012, 12:230-234. 10.1016/j.autrev.2012.07.008, 22796282.
    • (2012) Autoimmun Rev , vol.12 , pp. 230-234
    • Staub, H.L.1    Bertolaccini, M.L.2    Khamashta, M.A.3
  • 79
    • 4243094039 scopus 로고    scopus 로고
    • Antiphosphatidylethanolamine antibodies in recurrent early pregnancy loss and mid-to-late pregnancy loss
    • 10.1111/j.1447-0756.2004.00206.x, 15238112
    • Sugi T, Matsubayashi H, Inomo A, Dan L, Makino T. Antiphosphatidylethanolamine antibodies in recurrent early pregnancy loss and mid-to-late pregnancy loss. J Obstet Gynaecol Res 2004, 30:326-332. 10.1111/j.1447-0756.2004.00206.x, 15238112.
    • (2004) J Obstet Gynaecol Res , vol.30 , pp. 326-332
    • Sugi, T.1    Matsubayashi, H.2    Inomo, A.3    Dan, L.4    Makino, T.5
  • 80
    • 84856390339 scopus 로고    scopus 로고
    • Thin-layer chromatography immunostaining in detecting anti-phospholipid antibodies in seronegative anti-phospholipid syndrome
    • 10.1111/j.1365-2249.2011.04532.x, 3374275, 22288586
    • Conti F, Alessandri C, Sorice M, Capozzi A, Longo A, Garofalo T, Misasi R, Bompane D, Hughes GR, Khamashta MA, Valesini G. Thin-layer chromatography immunostaining in detecting anti-phospholipid antibodies in seronegative anti-phospholipid syndrome. Clin Exp Immunol 2012, 167:429-437. 10.1111/j.1365-2249.2011.04532.x, 3374275, 22288586.
    • (2012) Clin Exp Immunol , vol.167 , pp. 429-437
    • Conti, F.1    Alessandri, C.2    Sorice, M.3    Capozzi, A.4    Longo, A.5    Garofalo, T.6    Misasi, R.7    Bompane, D.8    Hughes, G.R.9    Khamashta, M.A.10    Valesini, G.11
  • 83
    • 0030005236 scopus 로고    scopus 로고
    • The pathogenic role of anti-phosphatidylserine antibodies: active immunization with the antibodies leads to the induction of antiphospholipid syndrome
    • 10.1006/clin.1996.0003, 8599879
    • Yodfat O, Blank M, Krause I, Shoenfeld Y. The pathogenic role of anti-phosphatidylserine antibodies: active immunization with the antibodies leads to the induction of antiphospholipid syndrome. Clin Immunol Immunopathol 1996, 78:14-20. 10.1006/clin.1996.0003, 8599879.
    • (1996) Clin Immunol Immunopathol , vol.78 , pp. 14-20
    • Yodfat, O.1    Blank, M.2    Krause, I.3    Shoenfeld, Y.4
  • 85
    • 84899067470 scopus 로고    scopus 로고
    • The clinical value of testing for Aphl, a new ELISA kit with a unique phospholipid mixture in patients with systemic lupus erythematosus (SLE)
    • Sciascia S, Sanna G, Murru V, Khamashta MA, Bertolaccini ML. The clinical value of testing for Aphl, a new ELISA kit with a unique phospholipid mixture in patients with systemic lupus erythematosus (SLE). Arthritis Rheum 2013, 65:S1.
    • (2013) Arthritis Rheum , vol.65
    • Sciascia, S.1    Sanna, G.2    Murru, V.3    Khamashta, M.A.4    Bertolaccini, M.L.5
  • 87
    • 77953624768 scopus 로고    scopus 로고
    • Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways
    • 10.4049/jimmunol.0902765, 2898497, 20483743
    • Lambrianides A, Carroll CJ, Pierangeli SS, Pericleous C, Branch W, Rice J, Latchman DS, Townsend P, Isenberg DA, Rhaman A, Giles IP. Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways. J Immunol 2010, 184:6622-6628. 10.4049/jimmunol.0902765, 2898497, 20483743.
    • (2010) J Immunol , vol.184 , pp. 6622-6628
    • Lambrianides, A.1    Carroll, C.J.2    Pierangeli, S.S.3    Pericleous, C.4    Branch, W.5    Rice, J.6    Latchman, D.S.7    Townsend, P.8    Isenberg, D.A.9    Rhaman, A.10    Giles, I.P.11
  • 88
    • 84861550718 scopus 로고    scopus 로고
    • Obstetric and vascular APS: same autoantibodies but different diseases?
    • 10.1177/0961203312438116, 22635208
    • Meroni PL, Raschi E, Grossi C, Pregnolato F, Trespidi L, Acaia B, Borghi MO. Obstetric and vascular APS: same autoantibodies but different diseases?. Lupus 2012, 21:708-710. 10.1177/0961203312438116, 22635208.
    • (2012) Lupus , vol.21 , pp. 708-710
    • Meroni, P.L.1    Raschi, E.2    Grossi, C.3    Pregnolato, F.4    Trespidi, L.5    Acaia, B.6    Borghi, M.O.7
  • 90
    • 79960646137 scopus 로고    scopus 로고
    • Molecular pathophysiology of the antiphospholipid syndrome: the role of oxidative post-translational modification of beta 2 glycoprotein I
    • Passam FH, Giannakopoulos B, Mirarabshahi P, Krilis SA. Molecular pathophysiology of the antiphospholipid syndrome: the role of oxidative post-translational modification of beta 2 glycoprotein I. J Thromb Haemost 2011, 9:275-282.
    • (2011) J Thromb Haemost , vol.9 , pp. 275-282
    • Passam, F.H.1    Giannakopoulos, B.2    Mirarabshahi, P.3    Krilis, S.A.4


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