-
1
-
-
0017075792
-
The granulomatous inflammatory response: a review
-
Adams DO. The granulomatous inflammatory response: a review. Am J Pathol. 1976;84(1):164–192.
-
(1976)
Am J Pathol
, vol.84
, Issue.1
, pp. 164-192
-
-
Adams, D.O.1
-
2
-
-
84887611505
-
ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis
-
Aguilo JI, Alonso H, Uranga S. ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis. Cell Microbiol. 2013;15(12):1994–2005.
-
(2013)
Cell Microbiol
, vol.15
, Issue.12
, pp. 1994-2005
-
-
Aguilo, J.I.1
Alonso, H.2
Uranga, S.3
-
3
-
-
84902536386
-
Phylogenetic relationships and classification of thiolases and thiolase-like proteins of Mycobacterium tuberculosis and Mycobacterium smegmatis
-
Anbazhagan P, Harijan RK, Kiema TR. Phylogenetic relationships and classification of thiolases and thiolase-like proteins of Mycobacterium tuberculosis and Mycobacterium smegmatis. Tuberculosis (Edinb). 2014;94(4):405–412.
-
(2014)
Tuberculosis (Edinb)
, vol.94
, Issue.4
, pp. 405-412
-
-
Anbazhagan, P.1
Harijan, R.K.2
Kiema, T.R.3
-
4
-
-
84906972186
-
High throughput screen identifies small molecule inhibitors specific for Mycobacterium tuberculosis phosphoserine phosphatase
-
Arora G, Tiwari P, Mandal RS. High throughput screen identifies small molecule inhibitors specific for Mycobacterium tuberculosis phosphoserine phosphatase. J Biol Chem. 2014;289(36):25149–25165.
-
(2014)
J Biol Chem
, vol.289
, Issue.36
, pp. 25149-25165
-
-
Arora, G.1
Tiwari, P.2
Mandal, R.S.3
-
5
-
-
79251578015
-
CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition
-
Barber DL, Mayer-Barber KD, Feng CG. CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition. J Immunol. 2011;186(3):1598–1607.
-
(2011)
J Immunol
, vol.186
, Issue.3
, pp. 1598-1607
-
-
Barber, D.L.1
Mayer-Barber, K.D.2
Feng, C.G.3
-
6
-
-
0014591375
-
Granuloma formation induced in mice by chemically defined mycobacterial fractions
-
Bekierkunst A, Levij IS, Yarkoni E. Granuloma formation induced in mice by chemically defined mycobacterial fractions. J Bacteriol. 1969;100(1):95–102.
-
(1969)
J Bacteriol
, vol.100
, Issue.1
, pp. 95-102
-
-
Bekierkunst, A.1
Levij, I.S.2
Yarkoni, E.3
-
7
-
-
0032561394
-
Attenuation of virulence by disruption of the Mycobacterium tuberculosis erp gene
-
Berthet FX, Lagranderie M, Gounon P. Attenuation of virulence by disruption of the Mycobacterium tuberculosis erp gene. Science. 1998;282(5389):759–762.
-
(1998)
Science
, vol.282
, Issue.5389
, pp. 759-762
-
-
Berthet, F.X.1
Lagranderie, M.2
Gounon, P.3
-
8
-
-
85046979825
-
Knockout mutation of p27–p55 operon severely reduces replication of Mycobacterium bovis in a macrophagic cell line and survival in a mouse model of infection
-
Bianco MV, Blanco FC, Forrellad MA. Knockout mutation of p27–p55 operon severely reduces replication of Mycobacterium bovis in a macrophagic cell line and survival in a mouse model of infection. Virulence. 2011;2(3):233–237.
-
(2011)
Virulence
, vol.2
, Issue.3
, pp. 233-237
-
-
Bianco, M.V.1
Blanco, F.C.2
Forrellad, M.A.3
-
9
-
-
10744228817
-
The knockout of the lprG-Rv1410 operon produces strong attenuation of Mycobacterium tuberculosis
-
Bigi F, Gioffré A, Klepp L. The knockout of the lprG-Rv1410 operon produces strong attenuation of Mycobacterium tuberculosis. Microbes Infect. 2004;6(2):182–187.
-
(2004)
Microbes Infect
, vol.6
, Issue.2
, pp. 182-187
-
-
Bigi, F.1
Gioffré, A.2
Klepp, L.3
-
10
-
-
0033819143
-
The ATP binding cassette (ABC) transport systems of Mycobacterium tuberculosis
-
Braibant M, Gilot P, Content J. The ATP binding cassette (ABC) transport systems of Mycobacterium tuberculosis. FEMS Microbiol Rev. 2000;24(4):449–467.
-
(2000)
FEMS Microbiol Rev
, vol.24
, Issue.4
, pp. 449-467
-
-
Braibant, M.1
Gilot, P.2
Content, J.3
-
11
-
-
29644438456
-
Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence
-
Brodin P, Majlessi L, Marsollier L. Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence. Infect Immun. 2006;74(1):88–98.
-
(2006)
Infect Immun
, vol.74
, Issue.1
, pp. 88-98
-
-
Brodin, P.1
Majlessi, L.2
Marsollier, L.3
-
12
-
-
0035827613
-
Analysis of the phthiocerol dimycocerosate locus of Mycobacterium tuberculosis: evidence that this lipid is involved in the cell wall permeability barrier
-
Camacho LR, Constant P, Raynaud C. Analysis of the phthiocerol dimycocerosate locus of Mycobacterium tuberculosis: evidence that this lipid is involved in the cell wall permeability barrier. J Biol Chem. 2001;276(23):19845–19854.
-
(2001)
J Biol Chem
, vol.276
, Issue.23
, pp. 19845-19854
-
-
Camacho, L.R.1
Constant, P.2
Raynaud, C.3
-
13
-
-
84892367843
-
Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids
-
Cambier CJ, Takaki KK, Larson RP. Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids. Nature. 2014;505(7482):218–222.
-
(2014)
Nature
, vol.505
, Issue.7482
, pp. 218-222
-
-
Cambier, C.J.1
Takaki, K.K.2
Larson, R.P.3
-
14
-
-
0141669013
-
Experimental Mycobacterium tuberculosis infection of cynomolgus macaques closely resembles the various manifestations of human M. tuberculosis infection
-
Capuano SV3, Croix DA, Pawar S. Experimental Mycobacterium tuberculosis infection of cynomolgus macaques closely resembles the various manifestations of human M. tuberculosis infection. Infect Immun. 2003;71(10):5831–5844.
-
(2003)
Infect Immun
, vol.71
, Issue.10
, pp. 5831-5844
-
-
Croix, D.A.1
Pawar, S.2
-
15
-
-
72149084120
-
Mycobacterial cytochrome p450 125 (cyp125) catalyzes the terminal hydroxylation of c27 steroids
-
Capyk JK, Kalscheuer R, Stewart GR. Mycobacterial cytochrome p450 125 (cyp125) catalyzes the terminal hydroxylation of c27 steroids. J Biol Chem. 2009;284(51):35534–35542.
-
(2009)
J Biol Chem
, vol.284
, Issue.51
, pp. 35534-35542
-
-
Capyk, J.K.1
Kalscheuer, R.2
Stewart, G.R.3
-
16
-
-
84956740578
-
A higher activation threshold of memory CD8+ T cells has a fitness cost that is modified by TCR affinity during tuberculosis
-
Carpenter SM, Nunes-Alves C, Booty MG. A higher activation threshold of memory CD8+ T cells has a fitness cost that is modified by TCR affinity during tuberculosis. PLoS Pathog. 2016;12(1):e1005380.
-
(2016)
PLoS Pathog
, vol.12
, Issue.1
, pp. e1005380
-
-
Carpenter, S.M.1
Nunes-Alves, C.2
Booty, M.G.3
-
17
-
-
22244455775
-
Rv0216, a conserved hypothetical protein from Mycobacterium tuberculosis that is essential for bacterial survival during infection, has a double hotdog fold
-
Castell A, Johansson P, Unge T. Rv0216, a conserved hypothetical protein from Mycobacterium tuberculosis that is essential for bacterial survival during infection, has a double hotdog fold. Protein Sci. 2005;14(7):1850–1862.
-
(2005)
Protein Sci
, vol.14
, Issue.7
, pp. 1850-1862
-
-
Castell, A.1
Johansson, P.2
Unge, T.3
-
18
-
-
34447554847
-
Identification of mycobacterial genes that alter growth and pathology in macrophages and in mice
-
Chang JC, Harik NS, Liao RP. Identification of mycobacterial genes that alter growth and pathology in macrophages and in mice. J Infect Dis. 2007;196(5):788–795.
-
(2007)
J Infect Dis
, vol.196
, Issue.5
, pp. 788-795
-
-
Chang, J.C.1
Harik, N.S.2
Liao, R.P.3
-
19
-
-
34447554847
-
Identification of mycobacterial genes that alter growth and pathology in macrophages and in mice
-
Chang JC, Harik NS, Liao RP. Identification of mycobacterial genes that alter growth and pathology in macrophages and in mice. J Infect Dis. 2007;196(5):788–795.
-
(2007)
J Infect Dis
, vol.196
, Issue.5
, pp. 788-795
-
-
Chang, J.C.1
Harik, N.S.2
Liao, R.P.3
-
20
-
-
67749095756
-
Igr Genes and Mycobacterium tuberculosis cholesterol metabolism
-
Chang JC, Miner MD, Pandey AK. igr Genes and Mycobacterium tuberculosis cholesterol metabolism. J Bacteriol. 2009;191(16):5232–5239.
-
(2009)
J Bacteriol
, vol.191
, Issue.16
, pp. 5232-5239
-
-
Chang, J.C.1
Miner, M.D.2
Pandey, A.K.3
-
21
-
-
84863116545
-
EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis
-
Chen JM, Boy-Röttger S, Dhar N. EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis. J Bacteriol. 2012;194(4):884–893.
-
(2012)
J Bacteriol
, vol.194
, Issue.4
, pp. 884-893
-
-
Chen, J.M.1
Boy-Röttger, S.2
Dhar, N.3
-
22
-
-
0036796243
-
Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of Mycobacterium tuberculosis
-
Choudhuri BS, Bhakta S, Barik R. Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of Mycobacterium tuberculosis. Biochem J. 2002;367(pt 1):279–285.
-
(2002)
Biochem J
, vol.367
, pp. 279-285
-
-
Choudhuri, B.S.1
Bhakta, S.2
Barik, R.3
-
23
-
-
48749114458
-
Tumor necrosis factor signaling mediates resistance to mycobacteria by inhibiting bacterial growth and macrophage death
-
Clay H, Volkman HE, Ramakrishnan L. Tumor necrosis factor signaling mediates resistance to mycobacteria by inhibiting bacterial growth and macrophage death. Immunity. 2008;29(2):283–294.
-
(2008)
Immunity
, vol.29
, Issue.2
, pp. 283-294
-
-
Clay, H.1
Volkman, H.E.2
Ramakrishnan, L.3
-
24
-
-
0032508046
-
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
-
Cole ST, Brosch R, Parkhill J. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature. 1998;393(6685):537–544.
-
(1998)
Nature
, vol.393
, Issue.6685
, pp. 537-544
-
-
Cole, S.T.1
Brosch, R.2
Parkhill, J.3
-
25
-
-
77952841173
-
Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved
-
Comas I, Chakravartti J, Small PM. Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved. Nat Genet. 2010;42(6):498–503.
-
(2010)
Nat Genet
, vol.42
, Issue.6
, pp. 498-503
-
-
Comas, I.1
Chakravartti, J.2
Small, P.M.3
-
26
-
-
84942604011
-
Mouse model of tuberculosis
-
6–a018556
-
Cooper AM. Mouse model of tuberculosis. Cold Spring Harb Perspect Med. 2015;5(2):a018556–a018556.
-
(2015)
Cold Spring Harb Perspect Med
, vol.5
, Issue.2
, pp. a01855
-
-
Cooper, A.M.1
-
27
-
-
84947417802
-
M. tuberculosis T cell epitope analysis reveals paucity of antigenic variation and identifies rare variable TB antigens
-
Coscolla M, Copin R, Sutherland J. M. tuberculosis T cell epitope analysis reveals paucity of antigenic variation and identifies rare variable TB antigens. Cell Host Microbe. 2015;18(5):538–548.
-
(2015)
Cell Host Microbe
, vol.18
, Issue.5
, pp. 538-548
-
-
Coscolla, M.1
Copin, R.2
Sutherland, J.3
-
28
-
-
33646948507
-
Mycobacterium marinum Erp is a virulence determinant required for cell wall integrity and intracellular survival
-
Cosma CL, Klein K, Kim R. Mycobacterium marinum Erp is a virulence determinant required for cell wall integrity and intracellular survival. Infect Immun. 2006;74(6):3125–3133.
-
(2006)
Infect Immun
, vol.74
, Issue.6
, pp. 3125-3133
-
-
Cosma, C.L.1
Klein, K.2
Kim, R.3
-
29
-
-
0033523971
-
Complex lipid determines tissue-specific replication of Mycobacterium tuberculosis in mice
-
Cox JS, Chen B, McNeil M. Complex lipid determines tissue-specific replication of Mycobacterium tuberculosis in mice. Nature. 1999;402(6757):79–83.
-
(1999)
Nature
, vol.402
, Issue.6757
, pp. 79-83
-
-
Cox, J.S.1
Chen, B.2
McNeil, M.3
-
30
-
-
84994882425
-
Macrophage epithelial reprogramming underlies mycobacterial granuloma formation and promotes infection
-
Cronan MR, Beerman RW, Rosenberg AF. Macrophage epithelial reprogramming underlies mycobacterial granuloma formation and promotes infection. Immunity. 2016;45(4):861–876.
-
(2016)
Immunity
, vol.45
, Issue.4
, pp. 861-876
-
-
Cronan, M.R.1
Beerman, R.W.2
Rosenberg, A.F.3
-
31
-
-
84903989880
-
Fit for consumption: zebrafish as a model for tuberculosis
-
Cronan MR, Tobin DM. Fit for consumption: zebrafish as a model for tuberculosis. Dis Model Mech. 2014;7(7):777–784.
-
(2014)
Dis Model Mech
, vol.7
, Issue.7
, pp. 777-784
-
-
Cronan, M.R.1
Tobin, D.M.2
-
32
-
-
58149083837
-
The role of the granuloma in expansion and dissemination of early tuberculous infection
-
Davis JM, Ramakrishnan L. The role of the granuloma in expansion and dissemination of early tuberculous infection. Cell. 2009;136(1):37–49.
-
(2009)
Cell
, vol.136
, Issue.1
, pp. 37-49
-
-
Davis, J.M.1
Ramakrishnan, L.2
-
33
-
-
84911408677
-
Mycobacterium tuberculosis strains lacking surface lipid phthiocerol dimycocerosate are susceptible to killing by an early innate host response
-
Day TA, Mittler JE, Nixon MR. Mycobacterium tuberculosis strains lacking surface lipid phthiocerol dimycocerosate are susceptible to killing by an early innate host response. Infect Immun. 2014;82(12):5214–5222.
-
(2014)
Infect Immun
, vol.82
, Issue.12
, pp. 5214-5222
-
-
Day, T.A.1
Mittler, J.E.2
Nixon, M.R.3
-
34
-
-
0037243052
-
The allele encoding the mycobacterial Erp protein affects lung disease in mice
-
De Mendonça Lima L, Bordat Y, Pivert E. The allele encoding the mycobacterial Erp protein affects lung disease in mice. Cell Microbiol. 2003;5(1):65–73.
-
(2003)
Cell Microbiol
, vol.5
, Issue.1
, pp. 65-73
-
-
De Mendonça Lima, L.1
Bordat, Y.2
Pivert, E.3
-
35
-
-
84871289607
-
The ESX-5 associated eccB5-eccC5 locus is essential for Mycobacterium tuberculosis viability
-
Di Luca M, Bottai D, Batoni G. The ESX-5 associated eccB5-eccC5 locus is essential for Mycobacterium tuberculosis viability. PLoS One. 2012;7(12):e52059.
-
(2012)
PLoS One
, vol.7
, Issue.12
, pp. e52059
-
-
Di Luca, M.1
Bottai, D.2
Batoni, G.3
-
36
-
-
84904042898
-
Tumor necrosis factor alpha in mycobacterial infection
-
Dorhoi A, Kaufmann S. Tumor necrosis factor alpha in mycobacterial infection. Semin Immunol. 2014;26(3):203–209.
-
(2014)
Semin Immunol
, vol.26
, Issue.3
, pp. 203-209
-
-
Dorhoi, A.1
Kaufmann, S.2
-
37
-
-
77956340123
-
Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2
-
Drage MG, Tsai HC, Pecora ND. Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2. Nat Struct Mol Biol. 2010;17(9):1088–1095.
-
(2010)
Nat Struct Mol Biol
, vol.17
, Issue.9
, pp. 1088-1095
-
-
Drage, M.G.1
Tsai, H.C.2
Pecora, N.D.3
-
38
-
-
38949096968
-
Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas
-
Egen JG, Rothfuchs AG, Feng CG. Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas. Immunity. 2008;28(2):271–284.
-
(2008)
Immunity
, vol.28
, Issue.2
, pp. 271-284
-
-
Egen, J.G.1
Rothfuchs, A.G.2
Feng, C.G.3
-
39
-
-
0032967118
-
Immunity to tuberculosis: a delicate balance between protection and pathology
-
Ehlers S. Immunity to tuberculosis: a delicate balance between protection and pathology. FEMS Immunol Med Microbiol. 1999;23(2):149–158.
-
(1999)
FEMS Immunol Med Microbiol
, vol.23
, Issue.2
, pp. 149-158
-
-
Ehlers, S.1
-
40
-
-
84940602262
-
Immune cell profiling to guide therapeutic decisions in rheumatic diseases
-
Ermann J, Rao DA, Teslovich NC. Immune cell profiling to guide therapeutic decisions in rheumatic diseases. Nat Rev Rheumatol. 2015;11(9):541–551.
-
(2015)
Nat Rev Rheumatol
, vol.11
, Issue.9
, pp. 541-551
-
-
Ermann, J.1
Rao, D.A.2
Teslovich, N.C.3
-
41
-
-
39749168415
-
Function of a mycobacterial major facilitator superfamily pump requires a membrane-associated lipoprotein
-
Farrow MF, Rubin EJ. Function of a mycobacterial major facilitator superfamily pump requires a membrane-associated lipoprotein. J Bacteriol. 2008;190(5):1783–1791.
-
(2008)
J Bacteriol
, vol.190
, Issue.5
, pp. 1783-1791
-
-
Farrow, M.F.1
Rubin, E.J.2
-
42
-
-
0038182023
-
Non-human primates: a model for tuberculosis research
-
Flynn JL, Capuano SV, Croix D. Non-human primates: a model for tuberculosis research. Tuberculosis (Edinb). 2003;83(1–3):116–118.
-
(2003)
Tuberculosis (Edinb)
, vol.83
, Issue.1-3
, pp. 116-118
-
-
Flynn, J.L.1
Capuano, S.V.2
Croix, D.3
-
43
-
-
0028979703
-
Tumor necrosis factor–alpha is required in the protective immune response against Mycobacterium tuberculosis in mice
-
Flynn JL, Goldstein MM, Chan J. Tumor necrosis factor–alpha is required in the protective immune response against Mycobacterium tuberculosis in mice. Immunity. 1995;2(6):561–572.
-
(1995)
Immunity
, vol.2
, Issue.6
, pp. 561-572
-
-
Flynn, J.L.1
Goldstein, M.M.2
Chan, J.3
-
44
-
-
84908635111
-
Cholesterol ester oxidation by mycobacterial cytochrome P450
-
Frank DJ, Madrona Y, Ortiz de Montellano PR. Cholesterol ester oxidation by mycobacterial cytochrome P450. J Biol Chem. 2014;289(44):30417–30425.
-
(2014)
J Biol Chem
, vol.289
, Issue.44
, pp. 30417-30425
-
-
Frank, D.J.1
Madrona, Y.2
Ortiz de Montellano, P.R.3
-
45
-
-
84907587038
-
LprG-mediated surface expression of lipoarabinomannan is essential for virulence of Mycobacterium tuberculosis
-
Gaur RL, Ren K, Blumenthal A. LprG-mediated surface expression of lipoarabinomannan is essential for virulence of Mycobacterium tuberculosis. PLoS Pathog. 2014;10(9):e1004376.
-
(2014)
PLoS Pathog
, vol.10
, Issue.9
, pp. e1004376
-
-
Gaur, R.L.1
Ren, K.2
Blumenthal, A.3
-
46
-
-
84859429244
-
Mycobacterium tuberculosis: success through dormancy
-
Gengenbacher M, Kaufmann SHE. Mycobacterium tuberculosis: success through dormancy. FEMS Microbiol Rev. 2012;36(3):514–532.
-
(2012)
FEMS Microbiol Rev
, vol.36
, Issue.3
, pp. 514-532
-
-
Gengenbacher, M.1
Kaufmann, S.H.E.2
-
47
-
-
80053459692
-
High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism
-
Griffin JE, Gawronski JD, DeJesus MA. High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism. PLoS Pathog. 2011;7(9):e1002251.
-
(2011)
PLoS Pathog
, vol.7
, Issue.9
, pp. e1002251
-
-
Griffin, J.E.1
Gawronski, J.D.2
DeJesus, M.A.3
-
48
-
-
84988689965
-
ESX secretion systems: mycobacterial evolution to counter host immunity
-
Gröschel MI, Sayes F, Simeone R. ESX secretion systems: mycobacterial evolution to counter host immunity. Nat Rev Micro. 2016;14(11):677–691.
-
(2016)
Nat Rev Micro
, vol.14
, Issue.11
, pp. 677-691
-
-
Gröschel, M.I.1
Sayes, F.2
Simeone, R.3
-
49
-
-
84984923597
-
Assembling of the Mycobacterium tuberculosis cell wall core
-
Grzegorzewicz AE, de Sousa-d’Auria C, McNeil MR. Assembling of the Mycobacterium tuberculosis cell wall core. J Biol Chem. 2016;291(36):18867–18879.
-
(2016)
J Biol Chem
, vol.291
, Issue.36
, pp. 18867-18879
-
-
Grzegorzewicz, A.E.1
de Sousa-d’Auria, C.2
McNeil, M.R.3
-
50
-
-
79952449129
-
Dominant TNF-α+ Mycobacterium tuberculosis–specific CD4+ T cell responses discriminate between latent infection and active disease
-
Harari A, Rozot V, Enders FB. Dominant TNF-α+ Mycobacterium tuberculosis–specific CD4+ T cell responses discriminate between latent infection and active disease. Nat Med. 2011;17(3):372–376.
-
(2011)
Nat Med
, vol.17
, Issue.3
, pp. 372-376
-
-
Harari, A.1
Rozot, V.2
Enders, F.B.3
-
51
-
-
84960421904
-
The MarR family transcription factor Rv1404 coordinates adaptation of Mycobacterium tuberculosis to acid stress via controlled expression of Rv1405c, a virulence-associated methyltransferase
-
Healy C, Golby P, MacHugh DE. The MarR family transcription factor Rv1404 coordinates adaptation of Mycobacterium tuberculosis to acid stress via controlled expression of Rv1405c, a virulence-associated methyltransferase. Tuberculosis (Edinb). 2016;97:154–162.
-
(2016)
Tuberculosis (Edinb)
, vol.97
, pp. 154-162
-
-
Healy, C.1
Golby, P.2
MacHugh, D.E.3
-
52
-
-
84863993689
-
ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria
-
Houben D, Demangel C, van Ingen J. ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria. Cell Microbiol. 2012;14(8):1287–1298.
-
(2012)
Cell Microbiol
, vol.14
, Issue.8
, pp. 1287-1298
-
-
Houben, D.1
Demangel, C.2
van Ingen, J.3
-
53
-
-
84960428524
-
Tuberculosis as a three-act play: a new paradigm for the pathogenesis of pulmonary tuberculosis
-
Hunter RL. Tuberculosis as a three-act play: a new paradigm for the pathogenesis of pulmonary tuberculosis. Tuberculosis (Edinb). 2016;97:8–17.
-
(2016)
Tuberculosis (Edinb)
, vol.97
, pp. 8-17
-
-
Hunter, R.L.1
-
54
-
-
34250742727
-
Pathology of postprimary tuberculosis in humans and mice: contradiction of long-held beliefs
-
Hunter RL, Jagannath C, Actor JK. Pathology of postprimary tuberculosis in humans and mice: contradiction of long-held beliefs. Tuberculosis (Edinb). 2007;87(4):267–278.
-
(2007)
Tuberculosis (Edinb)
, vol.87
, Issue.4
, pp. 267-278
-
-
Hunter, R.L.1
Jagannath, C.2
Actor, J.K.3
-
55
-
-
33645450141
-
Trehalose 6,6′-Dimycolate and lipid in the pathogenesis of caseating granulomas of tuberculosis in mice
-
Hunter RL, Olsen M, Jagannath C. Trehalose 6,6′-Dimycolate and lipid in the pathogenesis of caseating granulomas of tuberculosis in mice. Am J Pathol. 2006;168(4):1249–1261.
-
(2006)
Am J Pathol
, vol.168
, Issue.4
, pp. 1249-1261
-
-
Hunter, R.L.1
Olsen, M.2
Jagannath, C.3
-
56
-
-
34247617733
-
Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling
-
Jain M, Petzold CJ, Schelle MW. Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling. Proc Natl Acad Sci U S A. 2007;104(12):5133–5138.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.12
, pp. 5133-5138
-
-
Jain, M.1
Petzold, C.J.2
Schelle, M.W.3
-
57
-
-
84858962177
-
EccA1, a component of the Mycobacterium marinum ESX-1 protein virulence factor secretion pathway, regulates mycolic acid lipid synthesis
-
Joshi SA, Ball DA, Sun MG. EccA1, a component of the Mycobacterium marinum ESX-1 protein virulence factor secretion pathway, regulates mycolic acid lipid synthesis. Chem Biol. 2012;19(3):372–380.
-
(2012)
Chem Biol
, vol.19
, Issue.3
, pp. 372-380
-
-
Joshi, S.A.1
Ball, D.A.2
Sun, M.G.3
-
58
-
-
84940709339
-
Genetics of Mycobacterial Trehalose Metabolism
-
MGM2-0002-2013
-
Kalscheuer R, Koliwer-Brandl H. Genetics of Mycobacterial Trehalose Metabolism. Microbiol Spectr. 2014;2(3). MGM2-0002-2013. doi:10.1128/microbiolspec.MGM2-0002-2013.
-
(2014)
Microbiol Spectr
, vol.2
, Issue.3
-
-
Kalscheuer, R.1
Koliwer-Brandl, H.2
-
59
-
-
78650753476
-
Trehalose-recycling ABC transporter LpqY-SugA-SugB-SugC is essential for virulence of Mycobacterium tuberculosis
-
Kalscheuer R, Weinrick B, Veeraraghavan U. Trehalose-recycling ABC transporter LpqY-SugA-SugB-SugC is essential for virulence of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2010;107(50):21761–21766.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.50
, pp. 21761-21766
-
-
Kalscheuer, R.1
Weinrick, B.2
Veeraraghavan, U.3
-
60
-
-
84944346038
-
Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis
-
Kaushal D, Foreman TW, Gautam US. Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis. Nat Commun. 2015;6:8533.
-
(2015)
Nat Commun
, vol.6
, pp. 8533
-
-
Kaushal, D.1
Foreman, T.W.2
Gautam, U.S.3
-
61
-
-
24944529247
-
TNF-blocking agents and tuberculosis: new drugs illuminate an old topic
-
Keane J. TNF-blocking agents and tuberculosis: new drugs illuminate an old topic. Rheumatology. 2005;44(6):714–720.
-
(2005)
Rheumatology
, vol.44
, Issue.6
, pp. 714-720
-
-
Keane, J.1
-
62
-
-
34447567336
-
A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis
-
Kendall SL, Withers M, Soffair CN. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol Microbiol. 2007;65(3):684–699.
-
(2007)
Mol Microbiol
, vol.65
, Issue.3
, pp. 684-699
-
-
Kendall, S.L.1
Withers, M.2
Soffair, C.N.3
-
63
-
-
84959550074
-
Host-directed therapy targeting the Mycobacterium tuberculosis granuloma: a review
-
Kiran D, Podell BK, Chambers M. Host-directed therapy targeting the Mycobacterium tuberculosis granuloma: a review. Semin Immunopathol. 2016;38(2):167–183.
-
(2016)
Semin Immunopathol
, vol.38
, Issue.2
, pp. 167-183
-
-
Kiran, D.1
Podell, B.K.2
Chambers, M.3
-
64
-
-
60549093458
-
Identification of two proteins that interact with the Erp virulence factor from Mycobacterium tuberculosis by using the bacterial two-hybrid system
-
Klepp LI, Soria M, Blanco FC. Identification of two proteins that interact with the Erp virulence factor from Mycobacterium tuberculosis by using the bacterial two-hybrid system. BMC Mol Biol. 2009;10:3.
-
(2009)
BMC Mol Biol
, vol.10
, pp. 3
-
-
Klepp, L.I.1
Soria, M.2
Blanco, F.C.3
-
65
-
-
1342279431
-
The Erp protein is anchored at the surface by a carboxy-terminal hydrophobic domain and is important for cell-wall structure in Mycobacterium smegmatis
-
Kocíncová D, Sondén B, De Mendonça Lima L. The Erp protein is anchored at the surface by a carboxy-terminal hydrophobic domain and is important for cell-wall structure in Mycobacterium smegmatis. FEMS Microbiol Lett. 2004;231(2):191–196.
-
(2004)
FEMS Microbiol Lett
, vol.231
, Issue.2
, pp. 191-196
-
-
Kocíncová, D.1
Sondén, B.2
De Mendonça Lima, L.3
-
66
-
-
84959529153
-
Mouse models of human TB pathology: roles in the analysis of necrosis and the development of host-directed therapies
-
Kramnik I, Beamer G. Mouse models of human TB pathology: roles in the analysis of necrosis and the development of host-directed therapies. Semin Immunopathol. 2016;38(2):221–237.
-
(2016)
Semin Immunopathol
, vol.38
, Issue.2
, pp. 221-237
-
-
Kramnik, I.1
Beamer, G.2
-
67
-
-
84889844744
-
The structure of Rv3717 reveals a novel amidase from Mycobacterium tuberculosis
-
Kumar A, Kumar S, Kumar D. The structure of Rv3717 reveals a novel amidase from Mycobacterium tuberculosis. Acta Crystallogr D Biol Crystallogr. 2013;69(pt 12):2543–2554.
-
(2013)
Acta Crystallogr D Biol Crystallogr
, vol.69
, pp. 2543-2554
-
-
Kumar, A.1
Kumar, S.2
Kumar, D.3
-
68
-
-
0041694469
-
Development and maturation of the immune system in zebrafish, Danio rerio: a gene expression profiling, in situ hybridization and immunological study
-
Lam SH, Chua HL, Gong Z. Development and maturation of the immune system in zebrafish, Danio rerio: a gene expression profiling, in situ hybridization and immunological study. Dev Comp Immunol. 2004;28(1):9–28.
-
(2004)
Dev Comp Immunol
, vol.28
, Issue.1
, pp. 9-28
-
-
Lam, S.H.1
Chua, H.L.2
Gong, Z.3
-
69
-
-
44649197096
-
Differential fadE28 expression associated with phenotypic virulence of Mycobacterium tuberculosis
-
Lam THJ, Yuen KY, Ho PL. Differential fadE28 expression associated with phenotypic virulence of Mycobacterium tuberculosis. Microb Pathog. 2008;45(1):12–17.
-
(2008)
Microb Pathog
, vol.45
, Issue.1
, pp. 12-17
-
-
Lam, T.H.J.1
Yuen, K.Y.2
Ho, P.L.3
-
70
-
-
77955636377
-
Programmed death-1 (PD-1)–deficient mice are extraordinarily sensitive to tuberculosis
-
Lázár-Molnár E, Chen B, Sweeney KA. Programmed death-1 (PD-1)–deficient mice are extraordinarily sensitive to tuberculosis. Proc Natl Acad Sci U S A. 2010;107(30):13402–13407.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.30
, pp. 13402-13407
-
-
Lázár-Molnár, E.1
Chen, B.2
Sweeney, K.A.3
-
71
-
-
84874859777
-
Intracellular mycobacterium tuberculosis exploits host-derived fatty acids to limit metabolic stress
-
Lee W, VanderVen BC, Fahey RJ. Intracellular mycobacterium tuberculosis exploits host-derived fatty acids to limit metabolic stress. J Biol Chem. 2013;288(10):6788–6800.
-
(2013)
J Biol Chem
, vol.288
, Issue.10
, pp. 6788-6800
-
-
Lee, W.1
VanderVen, B.C.2
Fahey, R.J.3
-
72
-
-
0037219942
-
Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation
-
Lewis KN, Liao R, Guinn KM. Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation. J Infect Dis. 2003;187(1):117–123.
-
(2003)
J Infect Dis
, vol.187
, Issue.1
, pp. 117-123
-
-
Lewis, K.N.1
Liao, R.2
Guinn, K.M.3
-
73
-
-
84982958042
-
PET CT identifies reactivation risk in cynomolgus macaques with latent M. tuberculosis
-
Lin PL, Maiello P, Gideon HP. PET CT identifies reactivation risk in cynomolgus macaques with latent M. tuberculosis. PLoS Pathog. 2016;12(7):e1005739.
-
(2016)
PLoS Pathog
, vol.12
, Issue.7
, pp. e1005739
-
-
Lin, P.L.1
Maiello, P.2
Gideon, H.P.3
-
74
-
-
33745622432
-
Early events in Mycobacterium tuberculosis infection in cynomolgus macaques
-
Lin PL, Pawar S, Myers A. Early events in Mycobacterium tuberculosis infection in cynomolgus macaques. Infect Immun. 2006;74(7):3790–3803.
-
(2006)
Infect Immun
, vol.74
, Issue.7
, pp. 3790-3803
-
-
Lin, P.L.1
Pawar, S.2
Myers, A.3
-
75
-
-
84880070725
-
Structures of Mycobacterium tuberculosis FadD10 protein reveal a new type of adenylate-forming enzyme
-
Liu Z, Ioerger TR, Wang F, Sacchettini JC. Structures of Mycobacterium tuberculosis FadD10 protein reveal a new type of adenylate-forming enzyme. J Biol Chem. 2013;288(25):18473–18483.
-
(2013)
J Biol Chem
, vol.288
, Issue.25
, pp. 18473-18483
-
-
Liu, Z.1
Ioerger, T.R.2
Wang, F.3
Sacchettini, J.C.4
-
76
-
-
84949256765
-
The QTL within the H2 complex involved in the control of tuberculosis infection in mice is the classical class II H2–Ab1 gene
-
Logunova N, Korotetskaya M, Polshakov V. The QTL within the H2 complex involved in the control of tuberculosis infection in mice is the classical class II H2–Ab1 gene. PLoS Genet. 2015;11(11):e1005672.
-
(2015)
PLoS Genet
, vol.11
, Issue.11
, pp. e1005672
-
-
Logunova, N.1
Korotetskaya, M.2
Polshakov, V.3
-
77
-
-
84862067188
-
Mycobacterium tuberculosis modulates macrophage lipid-sensing nuclear receptors PPARγ and TR4 for survival
-
Mahajan S, Dkhar HK, Chandra V. Mycobacterium tuberculosis modulates macrophage lipid-sensing nuclear receptors PPARγ and TR4 for survival. J Immunol. 2012;188(11):5593–5603.
-
(2012)
J Immunol
, vol.188
, Issue.11
, pp. 5593-5603
-
-
Mahajan, S.1
Dkhar, H.K.2
Chandra, V.3
-
78
-
-
33749421509
-
7,8-Diaminoperlargonic acid aminotransferase from Mycobacterium tuberculosis, a potential therapeutic target: characterization and inhibition studies
-
Mann S, Ploux O. 7,8-Diaminoperlargonic acid aminotransferase from Mycobacterium tuberculosis, a potential therapeutic target: characterization and inhibition studies. FEBS J. 2006;273(20):4778–4789.
-
(2006)
FEBS J
, vol.273
, Issue.20
, pp. 4778-4789
-
-
Mann, S.1
Ploux, O.2
-
79
-
-
84956761544
-
Mycobacterial metabolic syndrome: LprG and Rv1410 regulate triacylglyceride levels, growth rate and virulence in Mycobacterium tuberculosis
-
Martinot AJ, Farrow M, Bai L. Mycobacterial metabolic syndrome: LprG and Rv1410 regulate triacylglyceride levels, growth rate and virulence in Mycobacterium tuberculosis. PLoS Pathog. 2016;12(1):e1005351.
-
(2016)
PLoS Pathog
, vol.12
, Issue.1
, pp. e1005351
-
-
Martinot, A.J.1
Farrow, M.2
Bai, L.3
-
80
-
-
19944427295
-
Mycobacterium tuberculosis pks12 produces a novel polyketide presented by CD1c to T cells
-
Matsunaga I, Bhatt A, Young DC. Mycobacterium tuberculosis pks12 produces a novel polyketide presented by CD1c to T cells. J Exp Med. 2004;200(12):1559–1569.
-
(2004)
J Exp Med
, vol.200
, Issue.12
, pp. 1559-1569
-
-
Matsunaga, I.1
Bhatt, A.2
Young, D.C.3
-
81
-
-
77049324025
-
The behavior of pulmonary tuberculous lesions; a pathological study
-
Medlar EM. The behavior of pulmonary tuberculous lesions; a pathological study. Lancet. 1956;76(4):82–88.
-
(1956)
Lancet
, vol.76
, Issue.4
, pp. 82-88
-
-
Medlar, E.M.1
-
82
-
-
79955044495
-
Rv3615c is a highly immunodominant RD1 (Region of Difference 1)–dependent secreted antigen specific for Mycobacterium tuberculosis infection
-
Millington KA, Fortune SM, Low J. Rv3615c is a highly immunodominant RD1 (Region of Difference 1)–dependent secreted antigen specific for Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A. 2011;108(14):5730–5735.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.14
, pp. 5730-5735
-
-
Millington, K.A.1
Fortune, S.M.2
Low, J.3
-
83
-
-
77957133396
-
Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome
-
Mishra BB, Moura Alves P, Sonawane A. Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome. Cell Microbiol. 2010;12(8):1046–1063.
-
(2010)
Cell Microbiol
, vol.12
, Issue.8
, pp. 1046-1063
-
-
Mishra, B.B.1
Moura Alves, P.2
Sonawane, A.3
-
84
-
-
84871188736
-
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1β
-
Mishra BB, Rathinam VAK, Martens GW. Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1β. Nat Immunol. 2013;14(1):52–60.
-
(2013)
Nat Immunol
, vol.14
, Issue.1
, pp. 52-60
-
-
Mishra, B.B.1
Rathinam, V.A.K.2
Martens, G.W.3
-
85
-
-
33644819211
-
Carbon metabolism of intracellular bacteria
-
Muñoz-Elías EJ, McKinney JD. Carbon metabolism of intracellular bacteria. Cell Microbiol. 2006;8(1):10–22.
-
(2006)
Cell Microbiol
, vol.8
, Issue.1
, pp. 10-22
-
-
Muñoz-Elías, E.J.1
McKinney, J.D.2
-
86
-
-
84944885441
-
Chemical probing suggests redox-regulation of the carbonic anhydrase activity of mycobacterial Rv1284
-
Nienaber L, Cave Freeman E, Cross M. Chemical probing suggests redox-regulation of the carbonic anhydrase activity of mycobacterial Rv1284. FEBS J. 2015;282(14):2708–2721.
-
(2015)
FEBS J
, vol.282
, Issue.14
, pp. 2708-2721
-
-
Nienaber, L.1
Cave Freeman, E.2
Cross, M.3
-
87
-
-
0027771385
-
Granuloma formation in severe combined immunodeficient (SCID) mice in response to progressive BCG infection: tendency not to form granulomas in the lung is associated with faster bacterial growth in this organ
-
North RJ, Izzo AA. Granuloma formation in severe combined immunodeficient (SCID) mice in response to progressive BCG infection: tendency not to form granulomas in the lung is associated with faster bacterial growth in this organ. Am J Pathol. 1993;142(6):1959–1966.
-
(1993)
Am J Pathol
, vol.142
, Issue.6
, pp. 1959-1966
-
-
North, R.J.1
Izzo, A.A.2
-
88
-
-
78649452380
-
Morphology and distribution of granulomatous inflammation in freshwater ornamental fish infected with mycobacteria
-
Novotny L, Halouzka R, Matlova L. Morphology and distribution of granulomatous inflammation in freshwater ornamental fish infected with mycobacteria. J Fish Dis. 2010;33(12):947–955.
-
(2010)
J Fish Dis
, vol.33
, Issue.12
, pp. 947-955
-
-
Novotny, L.1
Halouzka, R.2
Matlova, L.3
-
89
-
-
84925537336
-
Interception of host angiogenic signaling limits mycobacterial growth
-
Oehlers SH, Cronan MR, Scott NR. Interception of host angiogenic signaling limits mycobacterial growth. Nature. 2014;517(7536):612–615.
-
(2014)
Nature
, vol.517
, Issue.7536
, pp. 612-615
-
-
Oehlers, S.H.1
Cronan, M.R.2
Scott, N.R.3
-
90
-
-
84920117183
-
The formation of the granuloma in tuberculosis infection
-
Orme IM, Basaraba RJ. The formation of the granuloma in tuberculosis infection. Semin Immunol. 2014;26(6):601–609.
-
(2014)
Semin Immunol
, vol.26
, Issue.6
, pp. 601-609
-
-
Orme, I.M.1
Basaraba, R.J.2
-
91
-
-
41949119272
-
Mycobacterial persistence requires the utilization of host cholesterol
-
Pandey AK, Sassetti CM. Mycobacterial persistence requires the utilization of host cholesterol. Proc Natl Acad Sci U S A. 2008;105(11):4376–4380.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.11
, pp. 4376-4380
-
-
Pandey, A.K.1
Sassetti, C.M.2
-
92
-
-
84872026611
-
MprAB regulates the espA operon in Mycobacterium tuberculosis and modulates ESX-1 function and host cytokine response
-
Pang X, Samten B, Cao G. MprAB regulates the espA operon in Mycobacterium tuberculosis and modulates ESX-1 function and host cytokine response. J Bacteriol. 2013;195(1):66–75.
-
(2013)
J Bacteriol
, vol.195
, Issue.1
, pp. 66-75
-
-
Pang, X.1
Samten, B.2
Cao, G.3
-
93
-
-
34248364296
-
Functional complementation of the essential gene fabG1 of Mycobacterium tuberculosis by Mycobacterium smegmatis fabG but not Escherichia coli fabG
-
Parish T, Roberts G, Laval F. Functional complementation of the essential gene fabG1 of Mycobacterium tuberculosis by Mycobacterium smegmatis fabG but not Escherichia coli fabG. J Bacteriol. 2007;189(10):3721–3728.
-
(2007)
J Bacteriol
, vol.189
, Issue.10
, pp. 3721-3728
-
-
Parish, T.1
Roberts, G.2
Laval, F.3
-
94
-
-
84918538782
-
The Mycobacterium tuberculosis recombinant LprN protein of mce4 operon induces Th-1 type response deleterious to protection in mice
-
Pasricha R, Saini NK, Rathor N. The Mycobacterium tuberculosis recombinant LprN protein of mce4 operon induces Th-1 type response deleterious to protection in mice. Pathog Dis. 2014;72(3):188–196.
-
(2014)
Pathog Dis
, vol.72
, Issue.3
, pp. 188-196
-
-
Pasricha, R.1
Saini, N.K.2
Rathor, N.3
-
95
-
-
84922962816
-
Monkey models of tuberculosis: lessons learned
-
Peña JC, Ho WZ. Monkey models of tuberculosis: lessons learned. Infect Immun. 2015;83(3):852–862.
-
(2015)
Infect Immun
, vol.83
, Issue.3
, pp. 852-862
-
-
Peña, J.C.1
Ho, W.Z.2
-
96
-
-
84887103834
-
Structural and biochemical analyses of Mycobacterium tuberculosis N-acetylmuramyl-L-alanine amidase Rv3717 point to a role in peptidoglycan fragment recycling
-
Prigozhin DM, Mavrici D, Huizar JP. Structural and biochemical analyses of Mycobacterium tuberculosis N-acetylmuramyl-L-alanine amidase Rv3717 point to a role in peptidoglycan fragment recycling. J Biol Chem. 2013;288(44):31549–31555.
-
(2013)
J Biol Chem
, vol.288
, Issue.44
, pp. 31549-31555
-
-
Prigozhin, D.M.1
Mavrici, D.2
Huizar, J.P.3
-
97
-
-
84945470772
-
Mycobacterium tuberculosis oriC sequestration by MtrA response regulator
-
Purushotham G, Sarva KB, Blaszczyk E. Mycobacterium tuberculosis oriC sequestration by MtrA response regulator. Mol Microbiol. 2015;98(3):586–604.
-
(2015)
Mol Microbiol
, vol.98
, Issue.3
, pp. 586-604
-
-
Purushotham, G.1
Sarva, K.B.2
Blaszczyk, E.3
-
98
-
-
49649095178
-
Secreted transcription factor controls Mycobacterium tuberculosis virulence
-
Raghavan S, Manzanillo P, Chan K. Secreted transcription factor controls Mycobacterium tuberculosis virulence. Nature. 2008;454(7205):717–721.
-
(2008)
Nature
, vol.454
, Issue.7205
, pp. 717-721
-
-
Raghavan, S.1
Manzanillo, P.2
Chan, K.3
-
99
-
-
77952342938
-
Mycobacterium tuberculosis origin of replication and the promoter for immunodominant secreted antigen 85B are the targets of MtrA, the essential response regulator
-
Rajagopalan M, Dziedzic R, Al Zayer M. Mycobacterium tuberculosis origin of replication and the promoter for immunodominant secreted antigen 85B are the targets of MtrA, the essential response regulator. J Biol Chem. 2010;285(21):15816–15827.
-
(2010)
J Biol Chem
, vol.285
, Issue.21
, pp. 15816-15827
-
-
Rajagopalan, M.1
Dziedzic, R.2
Al Zayer, M.3
-
100
-
-
70349154626
-
Role of the Mycobacterium tuberculosis P55 efflux pump in intrinsic drug resistance, oxidative stress responses, and growth
-
Ramón-García S, Martín C, Thompson CJ. Role of the Mycobacterium tuberculosis P55 efflux pump in intrinsic drug resistance, oxidative stress responses, and growth. Antimicrob Agents Chemother. 2009;53(9):3675–3682.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, Issue.9
, pp. 3675-3682
-
-
Ramón-García, S.1
Martín, C.2
Thompson, C.J.3
-
101
-
-
38349125933
-
Mycobacterium tuberculosis Rv2224c modulates innate immune responses
-
Rengarajan J, Murphy E, Park A. Mycobacterium tuberculosis Rv2224c modulates innate immune responses. Proc Natl Acad Sci U S A. 2008;105(1):264–269.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.1
, pp. 264-269
-
-
Rengarajan, J.1
Murphy, E.2
Park, A.3
-
102
-
-
33646586698
-
Expression levels of Mycobacterium tuberculosis antigen-encoding genes versus production levels of antigen-specific T cells during stationary level lung infection in mice
-
Rogerson BJ, Jung YJ, LaCourse R. Expression levels of Mycobacterium tuberculosis antigen-encoding genes versus production levels of antigen-specific T cells during stationary level lung infection in mice. Immunology. 2006;118(2):195–201.
-
(2006)
Immunology
, vol.118
, Issue.2
, pp. 195-201
-
-
Rogerson, B.J.1
Jung, Y.J.2
LaCourse, R.3
-
103
-
-
1342325735
-
Production of phthiocerol dimycocerosates protects Mycobacterium tuberculosis from the cidal activity of reactive nitrogen intermediates produced by macrophages and modulates the early immune response to infection
-
Rousseau C, Winter N, Pivert E. Production of phthiocerol dimycocerosates protects Mycobacterium tuberculosis from the cidal activity of reactive nitrogen intermediates produced by macrophages and modulates the early immune response to infection. Cell Microbiol. 2004;6(3):277–287.
-
(2004)
Cell Microbiol
, vol.6
, Issue.3
, pp. 277-287
-
-
Rousseau, C.1
Winter, N.2
Pivert, E.3
-
104
-
-
69049108875
-
Foamy macrophages and the progression of the human tuberculosis granuloma
-
Russell DG, Cardona PJ, Kim MJ. Foamy macrophages and the progression of the human tuberculosis granuloma. Nat Immunol. 2009;10(9):943–948.
-
(2009)
Nat Immunol
, vol.10
, Issue.9
, pp. 943-948
-
-
Russell, D.G.1
Cardona, P.J.2
Kim, M.J.3
-
105
-
-
57249105493
-
Characterization of Mce4A protein of Mycobacterium tuberculosis: role in invasion and survival
-
Saini NK, Sharma M, Chandolia A. Characterization of Mce4A protein of Mycobacterium tuberculosis: role in invasion and survival. BMC Microbiol. 2008;8:200.
-
(2008)
BMC Microbiol
, vol.8
, pp. 200
-
-
Saini, N.K.1
Sharma, M.2
Chandolia, A.3
-
106
-
-
84986631520
-
Mce4A protein of Mycobacterium tuberculosis induces pro inflammatory cytokine response leading to macrophage apoptosis in a TNF-α dependent manner
-
Saini NK, Sinha R, Singh P. Mce4A protein of Mycobacterium tuberculosis induces pro inflammatory cytokine response leading to macrophage apoptosis in a TNF-α dependent manner. Microb Pathog. 2016;100:43–50.
-
(2016)
Microb Pathog
, vol.100
, pp. 43-50
-
-
Saini, N.K.1
Sinha, R.2
Singh, P.3
-
107
-
-
0242268400
-
Genetic requirements for mycobacterial survival during infection
-
Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proc Natl Acad Sci U S A. 2003;100(22):12989–12994.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.22
, pp. 12989-12994
-
-
Sassetti, C.M.1
Rubin, E.J.2
-
108
-
-
44349163542
-
Functional characterization of a vitamin B12-dependent methylmalonyl pathway in Mycobacterium tuberculosis: implications for propionate metabolism during growth on fatty acids
-
Savvi S, Warner DF, Kana BD. Functional characterization of a vitamin B12-dependent methylmalonyl pathway in Mycobacterium tuberculosis: implications for propionate metabolism during growth on fatty acids. J Bacteriol. 2008;190(11):3886–3895.
-
(2008)
J Bacteriol
, vol.190
, Issue.11
, pp. 3886-3895
-
-
Savvi, S.1
Warner, D.F.2
Kana, B.D.3
-
109
-
-
34447527891
-
Identification of a novel arabinofuranosyltransferase AftB involved in a terminal step of cell wall arabinan biosynthesis in Corynebacterianeae, such as Corynebacterium glutamicum and Mycobacterium tuberculosis
-
Seidel M, Alderwick LJ, Birch HL. Identification of a novel arabinofuranosyltransferase AftB involved in a terminal step of cell wall arabinan biosynthesis in Corynebacterianeae, such as Corynebacterium glutamicum and Mycobacterium tuberculosis. J Biol Chem. 2007;282(20):14729–14740.
-
(2007)
J Biol Chem
, vol.282
, Issue.20
, pp. 14729-14740
-
-
Seidel, M.1
Alderwick, L.J.2
Birch, H.L.3
-
110
-
-
84908349740
-
Mycobacterium tuberculosis lipoprotein LprG binds lipoarabinomannan and determines its cell envelope localization to control phagolysosomal fusion
-
Shukla S, Richardson ET, Athman JJ. Mycobacterium tuberculosis lipoprotein LprG binds lipoarabinomannan and determines its cell envelope localization to control phagolysosomal fusion. PLoS Pathog. 2014;10(10):e1004471.
-
(2014)
PLoS Pathog
, vol.10
, Issue.10
, pp. e1004471
-
-
Shukla, S.1
Richardson, E.T.2
Athman, J.J.3
-
111
-
-
84555202439
-
Phage transposon mutagenesis: Vaccine Design
-
Parish, Brown, (eds), Totowa, NJ, Humana Press,. In:, eds
-
Siegrist MS, Rubin EJ. Phage transposon mutagenesis: Vaccine Design. In: Parish T, Brown AC, eds. Vol 465. Methods in Molecular Biology. Totowa, NJ: Humana Press; 2010:311–323.
-
(2010)
Vol 465. Methods in Molecular Biology
, pp. 311-323
-
-
Siegrist, M.S.1
Rubin, E.J.2
-
112
-
-
84869176200
-
Mycobacterium tuberculosis–driven targeted recalibration of macrophage lipid homeostasis promotes the foamy phenotype
-
Singh V, Jamwal S, Jain R. Mycobacterium tuberculosis–driven targeted recalibration of macrophage lipid homeostasis promotes the foamy phenotype. Cell Host Microbe. 2012;12(5):669–681.
-
(2012)
Cell Host Microbe
, vol.12
, Issue.5
, pp. 669-681
-
-
Singh, V.1
Jamwal, S.2
Jain, R.3
-
113
-
-
84994472454
-
Tuberculosis susceptibility and vaccine protection are independently controlled by host genotype
-
Smith CM, Proulx MK, Olive AJ. Tuberculosis susceptibility and vaccine protection are independently controlled by host genotype. MBio. 2016;7(5): e01516.
-
(2016)
MBio
, vol.5
, pp. e01516
-
-
Smith, C.M.1
Proulx, M.K.2
Olive, A.J.3
-
114
-
-
84931560833
-
Evolutionary changes in the genome of Mycobacterium tuberculosis and the human genome from 9000 years BP until modern times
-
Spigelman M, Donoghue HD, Abdeen Z. Evolutionary changes in the genome of Mycobacterium tuberculosis and the human genome from 9000 years BP until modern times. Tuberculosis (Edinb). 2015;95(suppl 1):S145–S149.
-
(2015)
Tuberculosis (Edinb)
, vol.95
, pp. S145-S149
-
-
Spigelman, M.1
Donoghue, H.D.2
Abdeen, Z.3
-
115
-
-
84880670348
-
Cutting edge: direct recognition of infected cells by CD4 T cells is required for control of intracellular Mycobacterium tuberculosis in vivo
-
Srivastava S, Ernst JD. Cutting edge: direct recognition of infected cells by CD4 T cells is required for control of intracellular Mycobacterium tuberculosis in vivo. J Immunol. 2013;191(3):1016–1020.
-
(2013)
J Immunol
, vol.191
, Issue.3
, pp. 1016-1020
-
-
Srivastava, S.1
Ernst, J.D.2
-
116
-
-
33645737729
-
LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis
-
Sulzenbacher G, Canaan S, Bordat Y. LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis. EMBO J. 2006;25(7):1436–1444.
-
(2006)
EMBO J
, vol.25
, Issue.7
, pp. 1436-1444
-
-
Sulzenbacher, G.1
Canaan, S.2
Bordat, Y.3
-
117
-
-
84911997487
-
Mycobacterium smegmatis BioQ defines a new regulatory network for biotin metabolism
-
Tang Q, Li X, Zou T. Mycobacterium smegmatis BioQ defines a new regulatory network for biotin metabolism. Mol Microbiol. 2014;94(5):1006–1023.
-
(2014)
Mol Microbiol
, vol.94
, Issue.5
, pp. 1006-1023
-
-
Tang, Q.1
Li, X.2
Zou, T.3
-
118
-
-
22644436537
-
Mycobacterium tuberculosis appears to lack α-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes
-
Tian J, Bryk R, Shi S. Mycobacterium tuberculosis appears to lack α-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes. Mol Microbiol. 2005;57(3):859–868.
-
(2005)
Mol Microbiol
, vol.57
, Issue.3
, pp. 859-868
-
-
Tian, J.1
Bryk, R.2
Shi, S.3
-
119
-
-
84899419612
-
An immunomodulatory role for the Mycobacterium tuberculosis region of difference 1 locus proteins PE35 (Rv3872) and PPE68 (Rv3873)
-
Tiwari B, Soory A, Raghunand TR. An immunomodulatory role for the Mycobacterium tuberculosis region of difference 1 locus proteins PE35 (Rv3872) and PPE68 (Rv3873). FEBS J. 2014;281(6):1556–1570.
-
(2014)
FEBS J
, vol.281
, Issue.6
, pp. 1556-1570
-
-
Tiwari, B.1
Soory, A.2
Raghunand, T.R.3
-
120
-
-
80052330722
-
The steroid catabolic pathway of the intracellular pathogen Rhodococcus equi is important for pathogenesis and a target for vaccine development
-
van der Geize R, Grommen AWF, Hessels GI. The steroid catabolic pathway of the intracellular pathogen Rhodococcus equi is important for pathogenesis and a target for vaccine development. PLoS Pathog. 2011;7(8):e1002181.
-
(2011)
PLoS Pathog
, vol.7
, Issue.8
, pp. e1002181
-
-
van der Geize, R.1
Grommen, A.W.F.2
Hessels, G.I.3
-
121
-
-
0034529550
-
Control of latent Mycobacterium tuberculosis infection is dependent on CD8 T cells
-
van Pinxteren LA, Cassidy JP, Smedegaard BH. Control of latent Mycobacterium tuberculosis infection is dependent on CD8 T cells. Eur J Immunol. 2000;30(12):3689–3698.
-
(2000)
Eur J Immunol
, vol.30
, Issue.12
, pp. 3689-3698
-
-
van Pinxteren, L.A.1
Cassidy, J.P.2
Smedegaard, B.H.3
-
122
-
-
78751520936
-
Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes
-
Venugopal A, Bryk R, Shi S. Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes. Cell Host Microbe. 2011;9(1):21–31.
-
(2011)
Cell Host Microbe
, vol.9
, Issue.1
, pp. 21-31
-
-
Venugopal, A.1
Bryk, R.2
Shi, S.3
-
123
-
-
14044254749
-
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
-
Volkman HE, Clay H, Beery D. Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant. PLoS Biol. 2004;2(11):e367.
-
(2004)
PLoS Biol
, vol.2
, Issue.11
, pp. e367
-
-
Volkman, H.E.1
Clay, H.2
Beery, D.3
-
124
-
-
75649141266
-
Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium
-
Volkman HE, Pozos TC, Zheng J. Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium. Science. 2010;327(5964):466–469.
-
(2010)
Science
, vol.327
, Issue.5964
, pp. 466-469
-
-
Volkman, H.E.1
Pozos, T.C.2
Zheng, J.3
-
125
-
-
34248590375
-
Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence
-
Wang F, Langley R, Gulten G. Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence. Chem Biol. 2007;14(5):543–551.
-
(2007)
Chem Biol
, vol.14
, Issue.5
, pp. 543-551
-
-
Wang, F.1
Langley, R.2
Gulten, G.3
-
126
-
-
79251572061
-
Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccination
-
Woodworth JS, Shin D, Volman M. Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccination. J Immunol. 2011;186(3):1627–1637.
-
(2011)
J Immunol
, vol.186
, Issue.3
, pp. 1627-1637
-
-
Woodworth, J.S.1
Shin, D.2
Volman, M.3
-
127
-
-
80053459537
-
Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression
-
Woong Park S, Klotzsche M, Wilson DJ. Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression. PLoS Pathog. 2011;7(9):e1002264.
-
(2011)
PLoS Pathog
, vol.7
, Issue.9
, pp. e1002264
-
-
Woong Park, S.1
Klotzsche, M.2
Wilson, D.J.3
-
128
-
-
84941804623
-
Mycobacterium tuberculosis secreted proteins as potential biomarkers for the diagnosis of active tuberculosis and latent tuberculosis infection
-
Zhang C, Song X, Zhao Y. Mycobacterium tuberculosis secreted proteins as potential biomarkers for the diagnosis of active tuberculosis and latent tuberculosis infection. J Clin Lab Anal. 2015;29(5):375–382.
-
(2015)
J Clin Lab Anal
, vol.29
, Issue.5
, pp. 375-382
-
-
Zhang, C.1
Song, X.2
Zhao, Y.3
-
129
-
-
84973428379
-
Core component EccB1 of the Mycobacterium tuberculosis type VII secretion system is a periplasmic ATPase
-
Zhang XL, Li DF, Fleming J. Core component EccB1 of the Mycobacterium tuberculosis type VII secretion system is a periplasmic ATPase. FASEB J. 2015;29(12):4804–4814.
-
(2015)
FASEB J
, vol.29
, Issue.12
, pp. 4804-4814
-
-
Zhang, X.L.1
Li, D.F.2
Fleming, J.3
-
130
-
-
84890037649
-
Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing
-
Zhang YJ, Reddy MC, Ioerger TR. Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing. Cell. 2013;155(6):1296–1308.
-
(2013)
Cell
, vol.155
, Issue.6
, pp. 1296-1308
-
-
Zhang, Y.J.1
Reddy, M.C.2
Ioerger, T.R.3
|