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Volumn 12, Issue 1, 2016, Pages

A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 7 RECEPTOR; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; TUMOR NECROSIS FACTOR; BCG VACCINE; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84956740578     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005380     Document Type: Article
Times cited : (45)

References (83)
  • 1
    • 0025329959 scopus 로고
    • CD4+ T cell subsets. Lymphokine secretion of memory cells and of effector cells that develop from precursors in vitro
    • Swain SL, Weinberg AD, English M, CD4+ T cell subsets. Lymphokine secretion of memory cells and of effector cells that develop from precursors in vitro. J Immunol. 1990;144: 1788–1799. 1968490
    • (1990) J Immunol , vol.144 , pp. 1788-1799
    • Swain, S.L.1    Weinberg, A.D.2    English, M.3
  • 2
    • 0025918153 scopus 로고
    • Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development
    • Swain SL, Bradley LM, Croft M, Tonkonogy S, Atkins G, Weinberg AD, et al. Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development. Immunol Rev. 1991;123: 115–144. 1684776
    • (1991) Immunol Rev , vol.123 , pp. 115-144
    • Swain, S.L.1    Bradley, L.M.2    Croft, M.3    Tonkonogy, S.4    Atkins, G.5    Weinberg, A.D.6
  • 3
    • 71749113233 scopus 로고    scopus 로고
    • Diversity in T Cell Memory: An Embarrassment of Riches
    • Jameson SC, Masopust D, Diversity in T Cell Memory: An Embarrassment of Riches. Immunity. Elsevier Inc; 2009;31: 859–871. doi: 10.1016/j.immuni.2009.11.007 20064446
    • (2009) Immunity , vol.31 , pp. 859-871
    • Jameson, S.C.1    Masopust, D.2
  • 4
    • 0030001674 scopus 로고    scopus 로고
    • Immunological memory and protective immunity: understanding their relation
    • Ahmed R, Gray D, Immunological memory and protective immunity: understanding their relation. Science. 1996;272: 54–60. 8600537
    • (1996) Science , vol.272 , pp. 54-60
    • Ahmed, R.1    Gray, D.2
  • 6
    • 33749342911 scopus 로고    scopus 로고
    • Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection
    • Vezys V, Masopust D, Kemball CC, Barber DL, O'Mara LA, Larsen CP, et al. Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection. J Exp Med. 2006;203: 2263–2269. doi: 10.1084/jem.20060995 16966427
    • (2006) J Exp Med , vol.203 , pp. 2263-2269
    • Vezys, V.1    Masopust, D.2    Kemball, C.C.3    Barber, D.L.4    O'Mara, L.A.5    Larsen, C.P.6
  • 7
    • 80051882327 scopus 로고    scopus 로고
    • Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load
    • West EE, Youngblood B, Tan WG, Jin H-T, Araki K, Alexe G, et al. Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load. Immunity. 2011;35: 285–298. doi: 10.1016/j.immuni.2011.05.017 21856186
    • (2011) Immunity , vol.35 , pp. 285-298
    • West, E.E.1    Youngblood, B.2    Tan, W.G.3    Jin, H.-T.4    Araki, K.5    Alexe, G.6
  • 8
    • 0028981683 scopus 로고
    • Bacille Calmette-Guérin vaccines: a rough guide
    • Fine PE, Bacille Calmette-Guérin vaccines: a rough guide. CLIN INFECT DIS. 1995;20: 11–14. 7727635
    • (1995) CLIN INFECT DIS , vol.20 , pp. 11-14
    • Fine, P.E.1
  • 9
    • 0033231909 scopus 로고    scopus 로고
    • Beyond BCG: the potential for a more effective TB vaccine
    • Orme IM, Beyond BCG: the potential for a more effective TB vaccine. Mol Med Today. 1999;5: 487–492. 10529790
    • (1999) Mol Med Today , vol.5 , pp. 487-492
    • Orme, I.M.1
  • 10
    • 28344445877 scopus 로고    scopus 로고
    • Preclinical testing of new vaccines for tuberculosis: a comprehensive review
    • Orme IM, Preclinical testing of new vaccines for tuberculosis: a comprehensive review. Vaccine. 2006;24: 2–19. doi: 10.1016/j.vaccine.2005.07.078 16139397
    • (2006) Vaccine , vol.24 , pp. 2-19
    • Orme, I.M.1
  • 11
    • 84908145382 scopus 로고    scopus 로고
    • Memory T cell subsets in tuberculosis: what should we be targeting?
    • Henao-Tamayo M, Ordway DJ, Orme IM, Memory T cell subsets in tuberculosis: what should we be targeting? Tuberculosis (Edinb). 2014;94: 455–461. doi: 10.1016/j.tube.2014.05.001
    • (2014) Tuberculosis (Edinb) , vol.94 , pp. 455-461
    • Henao-Tamayo, M.1    Ordway, D.J.2    Orme, I.M.3
  • 12
    • 20444401506 scopus 로고    scopus 로고
    • Rate of reinfection tuberculosis after successful treatment is higher than rate of new tuberculosis
    • Verver S, Warren RM, Beyers N, Richardson M, van der Spuy GD, Borgdorff MW, et al. Rate of reinfection tuberculosis after successful treatment is higher than rate of new tuberculosis. Am J Respir Crit Care Med. 2005;171: 1430–1435. doi: 10.1164/rccm.200409-1200OC 15831840
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 1430-1435
    • Verver, S.1    Warren, R.M.2    Beyers, N.3    Richardson, M.4    van der Spuy, G.D.5    Borgdorff, M.W.6
  • 13
    • 77950909411 scopus 로고    scopus 로고
    • Risk factors for recurrent tuberculosis in England and Wales, 1998–2005
    • Crofts JP, Andrews NJ, Barker RD, Delpech V, Abubakar I, Risk factors for recurrent tuberculosis in England and Wales, 1998–2005. Thorax. BMJ Publishing Group Ltd and British Thoracic Society; 2010;65: 310–314. doi: 10.1136/thx.2009.124677 20388755
    • (2010) Thorax , vol.65 , pp. 310-314
    • Crofts, J.P.1    Andrews, N.J.2    Barker, R.D.3    Delpech, V.4    Abubakar, I.5
  • 14
    • 84878921853 scopus 로고    scopus 로고
    • Tuberculosis recurrence after completion treatment in a European city: reinfection or relapse?
    • Millet J-P, Shaw E, Orcau À, Casals M, Miro JM, Caylà JA, Mokrousov I, et al. Tuberculosis recurrence after completion treatment in a European city: reinfection or relapse? PLoS ONE. 2013;8: e64898. doi: 10.1371/journal.pone.0064898 23776440
    • (2013) PLoS ONE , vol.8 , pp. 64898
    • Millet, J.-P.1    Shaw, E.2    Orcau, À.3    Casals, M.4    Miro, J.M.5    Caylà, J.A.6    Mokrousov, I.7
  • 15
    • 22344448429 scopus 로고    scopus 로고
    • Properties and protective value of the secondary versus primary T helper type 1 response to airborne Mycobacterium tuberculosis infection in mice
    • Jung Y-J, Ryan L, LaCourse R, North RJ, Properties and protective value of the secondary versus primary T helper type 1 response to airborne Mycobacterium tuberculosis infection in mice. J Exp Med. 2005;201: 1915–1924. doi: 10.1084/jem.20050265 15955839
    • (2005) J Exp Med , vol.201 , pp. 1915-1924
    • Jung, Y.-J.1    Ryan, L.2    LaCourse, R.3    North, R.J.4
  • 16
    • 23944517342 scopus 로고    scopus 로고
    • Anamnestic responses of mice following Mycobacterium tuberculosis infection
    • Kamath AB, Behar SM, Anamnestic responses of mice following Mycobacterium tuberculosis infection. Infect Immun. 2005;73: 6110–6118. doi: 10.1128/IAI.73.9.6110–6118.2005 16113332
    • (2005) Infect Immun , vol.73 , pp. 6110-6118
    • Kamath, A.B.1    Behar, S.M.2
  • 17
    • 84929836024 scopus 로고    scopus 로고
    • CD8 T cells and Mycobacterium tuberculosis infection
    • Lin PL, Flynn JL, CD8 T cells and Mycobacterium tuberculosis infection. Semin Immunopathol. Springer Berlin Heidelberg; 2015;37: 239–249. doi: 10.1007/s00281-015-0490-8 25917388
    • (2015) Semin Immunopathol , vol.37 , pp. 239-249
    • Lin, P.L.1    Flynn, J.L.2
  • 18
    • 0027092074 scopus 로고
    • Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection
    • Flynn JL, Goldstein MM, Triebold KJ, Koller B, Bloom BR, Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc Natl Acad Sci USA. 1992;89: 12013–12017. 1465432
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 12013-12017
    • Flynn, J.L.1    Goldstein, M.M.2    Triebold, K.J.3    Koller, B.4    Bloom, B.R.5
  • 19
    • 0033591685 scopus 로고    scopus 로고
    • Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis
    • Behar SM, Dascher CC, Grusby MJ, Wang CR, Brenner MB, Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis. J Exp Med. 1999;189: 1973–1980. 10377193
    • (1999) J Exp Med , vol.189 , pp. 1973-1980
    • Behar, S.M.1    Dascher, C.C.2    Grusby, M.J.3    Wang, C.R.4    Brenner, M.B.5
  • 20
    • 0035808787 scopus 로고    scopus 로고
    • The relative importance of T cell subsets in immunity and immunopathology of airborne Mycobacterium tuberculosis infection in mice
    • Mogues T, Goodrich ME, Ryan L, LaCourse R, North RJ, The relative importance of T cell subsets in immunity and immunopathology of airborne Mycobacterium tuberculosis infection in mice. J Exp Med. 2001;193: 271–280. 11157048
    • (2001) J Exp Med , vol.193 , pp. 271-280
    • Mogues, T.1    Goodrich, M.E.2    Ryan, L.3    LaCourse, R.4    North, R.J.5
  • 21
    • 66349122656 scopus 로고    scopus 로고
    • A Critical Role for CD8 T Cells in a Nonhuman Primate Model of Tuberculosis
    • Chen CY, Huang D, Wang RC, Shen L, Zeng G, Yao S, Bishai W, et al. A Critical Role for CD8 T Cells in a Nonhuman Primate Model of Tuberculosis. PLoS Pathog. 2009;5: e1000392. doi: 10.1371/journal.ppat.1000392.g004 19381260
    • (2009) PLoS Pathog , vol.5 , pp. 1000392
    • Chen, C.Y.1    Huang, D.2    Wang, R.C.3    Shen, L.4    Zeng, G.5    Yao, S.6    Bishai, W.7
  • 22
    • 0034529550 scopus 로고    scopus 로고
    • Control of latent Mycobacterium tuberculosis infection is dependent on CD8 T cells
    • van Pinxteren LA, Cassidy JP, Smedegaard BH, Agger EM, Andersen P, Control of latent Mycobacterium tuberculosis infection is dependent on CD8 T cells. Eur J Immunol. 2000;30: 3689–3698. doi: 10.1002/1521-4141(200012)30:12<3689::AID-IMMU3689>3.0.CO;2–4 11169412
    • (2000) Eur J Immunol , vol.30 , pp. 3689-3698
    • van Pinxteren, L.A.1    Cassidy, J.P.2    Smedegaard, B.H.3    Agger, E.M.4    Andersen, P.5
  • 23
    • 66449083072 scopus 로고    scopus 로고
    • Anti-TNF immunotherapy reduces CD8+ T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humans
    • Bruns H, Meinken C, Schauenberg P, Härter G, Kern P, Modlin RL, et al. Anti-TNF immunotherapy reduces CD8+ T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humans. J Clin Invest. American Society for Clinical Investigation; 2009;119: 1167–1177. doi: 10.1172/JCI38482 19381021
    • (2009) J Clin Invest , vol.119 , pp. 1167-1177
    • Bruns, H.1    Meinken, C.2    Schauenberg, P.3    Härter, G.4    Kern, P.5    Modlin, R.L.6
  • 24
    • 84901312544 scopus 로고    scopus 로고
    • Human lung epithelial cells contain Mycobacterium tuberculosis in a late endosomal vacuole and are efficiently recognized by CD8⁺ T cells
    • Harriff MJ, Cansler ME, Toren KG, Canfield ET, Kwak S, Gold MC, Izzo AA, et al. Human lung epithelial cells contain Mycobacterium tuberculosis in a late endosomal vacuole and are efficiently recognized by CD8⁺ T cells. PLoS ONE. Public Library of Science; 2014;9: e97515. doi: 10.1371/journal.pone.0097515 24828674
    • (2014) PLoS ONE , vol.9 , pp. 97515
    • Harriff, M.J.1    Cansler, M.E.2    Toren, K.G.3    Canfield, E.T.4    Kwak, S.5    Gold, M.C.6    Izzo, A.A.7
  • 25
    • 84937516747 scopus 로고    scopus 로고
    • Safety and immunogenicity of candidate vaccine M72/AS01E in adolescents in a TB endemic setting
    • Penn-Nicholson A, Geldenhuys H, Burny W, van der Most R, Day CL, Jongert E, et al. Safety and immunogenicity of candidate vaccine M72/AS01E in adolescents in a TB endemic setting. Vaccine. 2015;33: 4025–4034. doi: 10.1016/j.vaccine.2015.05.088 26072017
    • (2015) Vaccine , vol.33 , pp. 4025-4034
    • Penn-Nicholson, A.1    Geldenhuys, H.2    Burny, W.3    van der Most, R.4    Day, C.L.5    Jongert, E.6
  • 26
    • 84908012098 scopus 로고    scopus 로고
    • The novel tuberculosis vaccine, AERAS-402, is safe in healthy infants previously vaccinated with BCG, and induces dose-dependent CD4 and CD8T cell responses
    • Kagina BMN, Tameris MD, Geldenhuys H, Hatherill M, Abel B, Hussey GD, et al. The novel tuberculosis vaccine, AERAS-402, is safe in healthy infants previously vaccinated with BCG, and induces dose-dependent CD4 and CD8T cell responses. Vaccine. Elsevier Ltd; 2014;32: 5908–5917. doi: 10.1016/j.vaccine.2014.09.001 25218194
    • (2014) Vaccine , vol.32 , pp. 5908-5917
    • Kagina, B.M.N.1    Tameris, M.D.2    Geldenhuys, H.3    Hatherill, M.4    Abel, B.5    Hussey, G.D.6
  • 27
    • 84875382846 scopus 로고    scopus 로고
    • Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial
    • Tameris MD, Hatherill M, Landry BS, Scriba TJ, Snowden MA, Lockhart S, et al. Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial. Lancet. 2013;381: 1021–1028. doi: 10.1016/S0140-6736(13)60177-4 23391465
    • (2013) Lancet , vol.381 , pp. 1021-1028
    • Tameris, M.D.1    Hatherill, M.2    Landry, B.S.3    Scriba, T.J.4    Snowden, M.A.5    Lockhart, S.6
  • 28
    • 77949409919 scopus 로고    scopus 로고
    • Extensive major histocompatibility complex class I binding promiscuity for Mycobacterium tuberculosis TB10.4 peptides and immune dominance of human leucocyte antigen (HLA)-B*0702 and HLA-B*0801 alleles in TB10.4 CD8 T-cell responses
    • Axelsson-Robertson R, Weichold F, Sizemore D, Wulf M, Skeiky YAW, Sadoff J, et al. Extensive major histocompatibility complex class I binding promiscuity for Mycobacterium tuberculosis TB10.4 peptides and immune dominance of human leucocyte antigen (HLA)-B*0702 and HLA-B*0801 alleles in TB10.4 CD8 T-cell responses. Immunology. 2010;129: 496–505. doi: 10.1111/j.1365-2567.2009.03201.x 20002212
    • (2010) Immunology , vol.129 , pp. 496-505
    • Axelsson-Robertson, R.1    Weichold, F.2    Sizemore, D.3    Wulf, M.4    Skeiky, Y.A.W.5    Sadoff, J.6
  • 29
    • 58849123775 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis-specific CD8+ T cells require perforin to kill target cells and provide protection in vivo
    • Woodworth JS, Wu Y, Behar SM, Mycobacterium tuberculosis-specific CD8+ T cells require perforin to kill target cells and provide protection in vivo. The Journal of Immunology. 2008;181: 8595–8603. 19050279
    • (2008) The Journal of Immunology , vol.181 , pp. 8595-8603
    • Woodworth, J.S.1    Wu, Y.2    Behar, S.M.3
  • 30
    • 84931573772 scopus 로고    scopus 로고
    • The tuberculosis vaccine H4:IC31 is safe and induces a persistent polyfunctional CD4 T cell response in South African adults: A randomized controlled trial
    • Geldenhuys H, Mearns H, Miles DJC, Tameris M, Hokey D, Shi Z, et al. The tuberculosis vaccine H4:IC31 is safe and induces a persistent polyfunctional CD4 T cell response in South African adults: A randomized controlled trial. Vaccine. 2015;33: 3592–3599. doi: 10.1016/j.vaccine.2015.05.036 26048780
    • (2015) Vaccine , vol.33 , pp. 3592-3599
    • Geldenhuys, H.1    Mearns, H.2    Miles, D.J.C.3    Tameris, M.4    Hokey, D.5    Shi, Z.6
  • 31
    • 0345701347 scopus 로고    scopus 로고
    • Genes required for mycobacterial growth defined by high density mutagenesis
    • Sassetti CM, Boyd DH, Rubin EJ, Genes required for mycobacterial growth defined by high density mutagenesis. Mol Microbiol. 2003;48: 77–84. 12657046
    • (2003) Mol Microbiol , vol.48 , pp. 77-84
    • Sassetti, C.M.1    Boyd, D.H.2    Rubin, E.J.3
  • 33
    • 84901847046 scopus 로고    scopus 로고
    • High-frequency vaccine-induced CD8⁺ T cells specific for an epitope naturally processed during infection with Mycobacterium tuberculosis do not confer protection
    • Lindenstrøm T, Aagaard C, Christensen D, Agger EM, Andersen P, High-frequency vaccine-induced CD8⁺ T cells specific for an epitope naturally processed during infection with Mycobacterium tuberculosis do not confer protection. Eur J Immunol. 2014;44: 1699–1709. doi: 10.1002/eji.201344358 24677089
    • (2014) Eur J Immunol , vol.44 , pp. 1699-1709
    • Lindenstrøm, T.1    Aagaard, C.2    Christensen, D.3    Agger, E.M.4    Andersen, P.5
  • 34
    • 1642362512 scopus 로고    scopus 로고
    • Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN
    • Ahonen CL, Doxsee CL, McGurran SM, Riter TR, Wade WF, Barth RJ, et al. Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN. J Exp Med. 2004;199: 775–784. doi: 10.1084/jem.20031591 15007094
    • (2004) J Exp Med , vol.199 , pp. 775-784
    • Ahonen, C.L.1    Doxsee, C.L.2    McGurran, S.M.3    Riter, T.R.4    Wade, W.F.5    Barth, R.J.6
  • 35
    • 71549172516 scopus 로고    scopus 로고
    • Optimized Peptide Vaccines Eliciting Extensive CD8 T-Cell Responses with Therapeutic Antitumor Effects
    • Cho HI, Celis E, Optimized Peptide Vaccines Eliciting Extensive CD8 T-Cell Responses with Therapeutic Antitumor Effects. Cancer Research. 2009;69: 9012–9019. doi: 10.1158/0008-5472.CAN-09-2019 19903852
    • (2009) Cancer Research , vol.69 , pp. 9012-9019
    • Cho, H.I.1    Celis, E.2
  • 36
    • 84869210900 scopus 로고    scopus 로고
    • Vaccine-elicited CD8+ T cells protect against respiratory syncytial virus strain A2-line19F-induced pathogenesis in BALB/c mice
    • Lee S, Stokes KL, Currier MG, Sakamoto K, Lukacs NW, Celis E, et al. Vaccine-elicited CD8+ T cells protect against respiratory syncytial virus strain A2-line19F-induced pathogenesis in BALB/c mice. Journal of virology. 2012;86: 13016–13024. doi: 10.1128/JVI.01770-12 23015695
    • (2012) Journal of virology , vol.86 , pp. 13016-13024
    • Lee, S.1    Stokes, K.L.2    Currier, M.G.3    Sakamoto, K.4    Lukacs, N.W.5    Celis, E.6
  • 37
    • 84855483647 scopus 로고    scopus 로고
    • A nonreplicating subunit vaccine protects mice against lethal Ebola virus challenge
    • Phoolcharoen W, Dye JM, Kilbourne J, Piensook K, Pratt WD, Arntzen CJ, et al. A nonreplicating subunit vaccine protects mice against lethal Ebola virus challenge. Proc Natl Acad Sci USA. 2011;108: 20695–20700. doi: 10.1073/pnas.1117715108 22143779
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 20695-20700
    • Phoolcharoen, W.1    Dye, J.M.2    Kilbourne, J.3    Piensook, K.4    Pratt, W.D.5    Arntzen, C.J.6
  • 38
    • 0347382593 scopus 로고    scopus 로고
    • Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
    • Kaech SM, Tan JT, Wherry EJ, Konieczny BT, Surh CD, Ahmed R, Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat Immunol. 2003;4: 1191–1198. doi: 10.1038/ni1009 14625547
    • (2003) Nat Immunol , vol.4 , pp. 1191-1198
    • Kaech, S.M.1    Tan, J.T.2    Wherry, E.J.3    Konieczny, B.T.4    Surh, C.D.5    Ahmed, R.6
  • 39
    • 34548027000 scopus 로고    scopus 로고
    • Inflammation Directs Memory Precursor and Short-Lived Effector CD8+ T Cell Fates via the Graded Expression of T-bet Transcription Factor
    • Joshi NS, Cui W, Chandele A, Lee HK, Urso DR, Hagman J, et al. Inflammation Directs Memory Precursor and Short-Lived Effector CD8+ T Cell Fates via the Graded Expression of T-bet Transcription Factor. Immunity. 2007;27: 281–295. doi: 10.1016/j.immuni.2007.07.010 17723218
    • (2007) Immunity , vol.27 , pp. 281-295
    • Joshi, N.S.1    Cui, W.2    Chandele, A.3    Lee, H.K.4    Urso, D.R.5    Hagman, J.6
  • 40
    • 81455135900 scopus 로고    scopus 로고
    • Pathogen-induced inflammatory environment controls effector and memory CD8+ T cell differentiation
    • Obar JJ, Jellison ER, Sheridan BS, Blair DA, Pham Q-M, Zickovich JM, et al. Pathogen-induced inflammatory environment controls effector and memory CD8+ T cell differentiation. The Journal of Immunology. American Association of Immunologists; 2011;187: 4967–4978. doi: 10.4049/jimmunol.1102335 21987662
    • (2011) The Journal of Immunology , vol.187 , pp. 4967-4978
    • Obar, J.J.1    Jellison, E.R.2    Sheridan, B.S.3    Blair, D.A.4    Pham, Q.-M.5    Zickovich, J.M.6
  • 41
    • 84884268174 scopus 로고    scopus 로고
    • CD8⁺ T cells produce the chemokine CXCL10 in response to CD27/CD70 costimulation to promote generation of the CD8⁺ effector T cell pool
    • Peperzak V, Veraar EAM, Xiao Y, Babala N, Thiadens K, Brugmans M, et al. CD8⁺ T cells produce the chemokine CXCL10 in response to CD27/CD70 costimulation to promote generation of the CD8⁺ effector T cell pool. The Journal of Immunology. 2013;191: 3025–3036. doi: 10.4049/jimmunol.1202222 23940275
    • (2013) The Journal of Immunology , vol.191 , pp. 3025-3036
    • Peperzak, V.1    Veraar, E.A.M.2    Xiao, Y.3    Babala, N.4    Thiadens, K.5    Brugmans, M.6
  • 42
    • 84887515800 scopus 로고    scopus 로고
    • Lung airway-surveilling CXCR3(hi) memory CD8(+) T cells are critical for protection against influenza A virus
    • Slütter B, Pewe LL, Kaech SM, Harty JT, Lung airway-surveilling CXCR3(hi) memory CD8(+) T cells are critical for protection against influenza A virus. Immunity. 2013;39: 939–948. doi: 10.1016/j.immuni.2013.09.013 24238342
    • (2013) Immunity , vol.39 , pp. 939-948
    • Slütter, B.1    Pewe, L.L.2    Kaech, S.M.3    Harty, J.T.4
  • 43
    • 33748847250 scopus 로고    scopus 로고
    • Antigen-specific CD8+ T cells and the development of central memory during Mycobacterium tuberculosis infection
    • Kamath A, Woodworth JSM, Behar SM, Antigen-specific CD8+ T cells and the development of central memory during Mycobacterium tuberculosis infection. J Immunol. 2006;177: 6361–6369. 17056567
    • (2006) J Immunol , vol.177 , pp. 6361-6369
    • Kamath, A.1    Woodworth, J.S.M.2    Behar, S.M.3
  • 44
    • 77956628455 scopus 로고    scopus 로고
    • Immediate-early expression of a recombinant antigen by modified vaccinia virus ankara breaks the immunodominance of strong vector-specific B8R antigen in acute and memory CD8 T-cell responses
    • Baur K, Brinkmann K, Schweneker M, Pätzold J, Meisinger-Henschel C, Hermann J, et al. Immediate-early expression of a recombinant antigen by modified vaccinia virus ankara breaks the immunodominance of strong vector-specific B8R antigen in acute and memory CD8 T-cell responses. Journal of virology. American Society for Microbiology; 2010;84: 8743–8752. doi: 10.1128/JVI.00604-10 20538860
    • (2010) Journal of virology , vol.84 , pp. 8743-8752
    • Baur, K.1    Brinkmann, K.2    Schweneker, M.3    Pätzold, J.4    Meisinger-Henschel, C.5    Hermann, J.6
  • 45
    • 84897954314 scopus 로고    scopus 로고
    • Structure-based programming of lymph-node targeting in molecular vaccines
    • Liu H, Moynihan KD, Zheng Y, Szeto GL, Li AV, Huang B, et al. Structure-based programming of lymph-node targeting in molecular vaccines. Nature. 2014;507: 519–522. doi: 10.1038/nature12978 24531764
    • (2014) Nature , vol.507 , pp. 519-522
    • Liu, H.1    Moynihan, K.D.2    Zheng, Y.3    Szeto, G.L.4    Li, A.V.5    Huang, B.6
  • 46
    • 38749138163 scopus 로고    scopus 로고
    • Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs
    • Wolf AJ, Desvignes L, Linas B, Banaiee N, Tamura T, Takatsu K, et al. Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs. Journal of Experimental Medicine. 2008;205: 105–115. doi: 10.1084/jem.20071367 18158321
    • (2008) Journal of Experimental Medicine , vol.205 , pp. 105-115
    • Wolf, A.J.1    Desvignes, L.2    Linas, B.3    Banaiee, N.4    Tamura, T.5    Takatsu, K.6
  • 47
    • 84897494143 scopus 로고    scopus 로고
    • Cutting edge: control of Mycobacterium tuberculosis infection by a subset of lung parenchyma-homing CD4 T cells
    • Sakai S, Kauffman KD, Schenkel JM, McBerry CC, Mayer-Barber KD, Masopust D, et al. Cutting edge: control of Mycobacterium tuberculosis infection by a subset of lung parenchyma-homing CD4 T cells. The Journal of Immunology. 2014;192: 2965–2969. doi: 10.4049/jimmunol.1400019 24591367
    • (2014) The Journal of Immunology , vol.192 , pp. 2965-2969
    • Sakai, S.1    Kauffman, K.D.2    Schenkel, J.M.3    McBerry, C.C.4    Mayer-Barber, K.D.5    Masopust, D.6
  • 48
    • 84934889059 scopus 로고    scopus 로고
    • ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis
    • Moguche AO, Shafiani S, Clemons C, Larson RP, Dinh C, Higdon LE, et al. ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis. Journal of Experimental Medicine. 2015;212: 715–728. doi: 10.1084/jem.20141518 25918344
    • (2015) Journal of Experimental Medicine , vol.212 , pp. 715-728
    • Moguche, A.O.1    Shafiani, S.2    Clemons, C.3    Larson, R.P.4    Dinh, C.5    Higdon, L.E.6
  • 49
    • 77956335589 scopus 로고    scopus 로고
    • Fidelity of pathogen-specific CD4+ T cells to the Th1 lineage is controlled by exogenous cytokines, interferon-gamma expression, and pathogen lifestyle
    • Curtis MM, Rowell E, Shafiani S, Negash A, Urdahl KB, Wilson CB, et al. Fidelity of pathogen-specific CD4+ T cells to the Th1 lineage is controlled by exogenous cytokines, interferon-gamma expression, and pathogen lifestyle. Cell Host and Microbe. 2010;8: 163–173. doi: 10.1016/j.chom.2010.07.006 20709293
    • (2010) Cell Host and Microbe , vol.8 , pp. 163-173
    • Curtis, M.M.1    Rowell, E.2    Shafiani, S.3    Negash, A.4    Urdahl, K.B.5    Wilson, C.B.6
  • 50
    • 84879604666 scopus 로고    scopus 로고
    • Pathogen-specific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12
    • Shafiani S, Dinh C, Ertelt JM, Moguche AO, Siddiqui I, Smigiel KS, et al. Pathogen-specific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12. Immunity. 2013;38: 1261–1270. doi: 10.1016/j.immuni.2013.06.003 23791647
    • (2013) Immunity , vol.38 , pp. 1261-1270
    • Shafiani, S.1    Dinh, C.2    Ertelt, J.M.3    Moguche, A.O.4    Siddiqui, I.5    Smigiel, K.S.6
  • 51
    • 84893719649 scopus 로고    scopus 로고
    • Memory CD8+ T cells exhibit increased antigen threshold requirements for recall proliferation
    • Mehlhop-Williams ER, Bevan MJ, Memory CD8+ T cells exhibit increased antigen threshold requirements for recall proliferation. Journal of Experimental Medicine. 2014;211: 345–356. doi: 10.1084/jem.20131271 24493801
    • (2014) Journal of Experimental Medicine , vol.211 , pp. 345-356
    • Mehlhop-Williams, E.R.1    Bevan, M.J.2
  • 52
    • 84897494143 scopus 로고    scopus 로고
    • Cutting Edge: Control of Mycobacterium tuberculosis Infection by a Subset of Lung Parenchyma-Homing CD4 T Cells
    • Sakai S, Kauffman KD, Schenkel JM, McBerry CC, Mayer-Barber KD, Masopust D, et al. Cutting Edge: Control of Mycobacterium tuberculosis Infection by a Subset of Lung Parenchyma-Homing CD4 T Cells. The Journal of Immunology. American Association of Immunologists; 2014;192: 1400019–2969. doi: 10.4049/jimmunol.1400019
    • (2014) The Journal of Immunology , vol.192 , pp. 1400019-1402969
    • Sakai, S.1    Kauffman, K.D.2    Schenkel, J.M.3    McBerry, C.C.4    Mayer-Barber, K.D.5    Masopust, D.6
  • 53
    • 84856574224 scopus 로고    scopus 로고
    • Population dynamics of naive and memory CD8 T cell responses after antigen stimulations in vivo
    • Martin MD, Condotta SA, Harty JT, Badovinac VP, Population dynamics of naive and memory CD8 T cell responses after antigen stimulations in vivo. The Journal of Immunology. 2012;188: 1255–1265. doi: 10.4049/jimmunol.1101579 22205031
    • (2012) The Journal of Immunology , vol.188 , pp. 1255-1265
    • Martin, M.D.1    Condotta, S.A.2    Harty, J.T.3    Badovinac, V.P.4
  • 54
    • 84867911387 scopus 로고    scopus 로고
    • Development of memory CD8+ T cells and their recall responses during blood-stage infection with Plasmodium berghei ANKA
    • Miyakoda M, Kimura D, Honma K, Kimura K, Yuda M, Yui K, Development of memory CD8+ T cells and their recall responses during blood-stage infection with Plasmodium berghei ANKA. The Journal of Immunology. American Association of Immunologists; 2012;189: 4396–4404. doi: 10.4049/jimmunol.1200781 23008449
    • (2012) The Journal of Immunology , vol.189 , pp. 4396-4404
    • Miyakoda, M.1    Kimura, D.2    Honma, K.3    Kimura, K.4    Yuda, M.5    Yui, K.6
  • 55
    • 0028872014 scopus 로고
    • Variation in protection by BCG: implications of and for heterologous immunity
    • Fine PE, Variation in protection by BCG: implications of and for heterologous immunity. Lancet. 1995;346: 1339–1345. 7475776
    • (1995) Lancet , vol.346 , pp. 1339-1345
    • Fine, P.E.1
  • 56
    • 0344289512 scopus 로고    scopus 로고
    • Exogenous reinfection as a cause of recurrent tuberculosis after curative treatment
    • van Rie A, Warren R, Richardson M, Victor TC, Gie RP, Enarson DA, et al. Exogenous reinfection as a cause of recurrent tuberculosis after curative treatment. N Engl J Med. 1999;341: 1174–1179. doi: 10.1056/NEJM199910143411602 10519895
    • (1999) N Engl J Med , vol.341 , pp. 1174-1179
    • van Rie, A.1    Warren, R.2    Richardson, M.3    Victor, T.C.4    Gie, R.P.5    Enarson, D.A.6
  • 57
    • 33745113799 scopus 로고    scopus 로고
    • Establishment and recall of CD8+ T-cell memory in a model of localized transient infection
    • Kedzierska K, La Gruta NL, Turner SJ, Doherty PC, Establishment and recall of CD8+ T-cell memory in a model of localized transient infection. Immunol Rev. Blackwell Publishing Ltd; 2006;211: 133–145. doi: 10.1111/j.0105-2896.2006.00386.x
    • (2006) Immunol Rev. Blackwell Publishing Ltd , vol.211 , pp. 133-145
    • Kedzierska, K.1    La Gruta, N.L.2    Turner, S.J.3    Doherty, P.C.4
  • 58
    • 0028023462 scopus 로고
    • Lymphocyte life-span and memory
    • Sprent J, Tough DF, Lymphocyte life-span and memory. Science. 1994;265: 1395–1400. 8073282
    • (1994) Science , vol.265 , pp. 1395-1400
    • Sprent, J.1    Tough, D.F.2
  • 59
    • 0034231222 scopus 로고    scopus 로고
    • Response of naïve and memory CD8+ T cells to antigen stimulation in vivo
    • Veiga-Fernandes H, Walter U, Bourgeois C, McLean A, Rocha B, Response of naïve and memory CD8+ T cells to antigen stimulation in vivo. Nat Immunol. 2000;1: 47–53. doi: 10.1038/76907 10881174
    • (2000) Nat Immunol , vol.1 , pp. 47-53
    • Veiga-Fernandes, H.1    Walter, U.2    Bourgeois, C.3    McLean, A.4    Rocha, B.5
  • 60
    • 0036078710 scopus 로고    scopus 로고
    • Dissemination of Mycobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity
    • Chackerian AA, Alt JM, Perera TV, Dascher CC, Behar SM, Dissemination of Mycobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity. Infect Immun. 2002;70: 4501–4509. 12117962
    • (2002) Infect Immun , vol.70 , pp. 4501-4509
    • Chackerian, A.A.1    Alt, J.M.2    Perera, T.V.3    Dascher, C.C.4    Behar, S.M.5
  • 61
    • 23844545821 scopus 로고    scopus 로고
    • In vivo depletion of CD11c+ cells delays the CD4+ T cell response to Mycobacterium tuberculosis and exacerbates the outcome of infection
    • Tian T, Woodworth J, Sköld M, Behar SM, In vivo depletion of CD11c+ cells delays the CD4+ T cell response to Mycobacterium tuberculosis and exacerbates the outcome of infection. J Immunol. 2005;175: 3268–3272. 16116218
    • (2005) J Immunol , vol.175 , pp. 3268-3272
    • Tian, T.1    Woodworth, J.2    Sköld, M.3    Behar, S.M.4
  • 62
    • 42949120641 scopus 로고    scopus 로고
    • Vaccine-elicited 10-kilodalton culture filtrate protein-specific CD8+ T cells are sufficient to mediate protection against Mycobacterium tuberculosis infection
    • Wu Y, Woodworth JS, Shin DS, Morris SL, Behar SM, Vaccine-elicited 10-kilodalton culture filtrate protein-specific CD8+ T cells are sufficient to mediate protection against Mycobacterium tuberculosis infection. Infect Immun. 2008;76: 2249–2255. doi: 10.1128/IAI.00024-08 18332205
    • (2008) Infect Immun , vol.76 , pp. 2249-2255
    • Wu, Y.1    Woodworth, J.S.2    Shin, D.S.3    Morris, S.L.4    Behar, S.M.5
  • 63
    • 1342302485 scopus 로고    scopus 로고
    • Immunization with a DNA vaccine cocktail protects mice lacking CD4 cells against an aerogenic infection with Mycobacterium tuberculosis
    • Derrick SC, Repique C, Snoy P, Yang AL, Morris S, Immunization with a DNA vaccine cocktail protects mice lacking CD4 cells against an aerogenic infection with Mycobacterium tuberculosis. Infect Immun. 2004;72: 1685–1692. doi: 10.1128/IAI.72.3.1685–1692.2004 14977976
    • (2004) Infect Immun , vol.72 , pp. 1685-1692
    • Derrick, S.C.1    Repique, C.2    Snoy, P.3    Yang, A.L.4    Morris, S.5
  • 64
    • 52949138683 scopus 로고    scopus 로고
    • Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria
    • Schmidt NW, Podyminogin RL, Butler NS, Badovinac VP, Tucker BJ, Bahjat KS, et al. Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria. Proc Natl Acad Sci USA. National Acad Sciences; 2008;105: 14017–14022. doi: 10.1073/pnas.0805452105 18780790
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14017-14022
    • Schmidt, N.W.1    Podyminogin, R.L.2    Butler, N.S.3    Badovinac, V.P.4    Tucker, B.J.5    Bahjat, K.S.6
  • 65
    • 84893360867 scopus 로고    scopus 로고
    • Reproducible selection of high avidity CD8+ T-cell clones following secondary acute virus infection
    • Cukalac T, Chadderton J, Handel A, Doherty PC, Turner SJ, Thomas PG, et al. Reproducible selection of high avidity CD8+ T-cell clones following secondary acute virus infection. Proc Natl Acad Sci USA. National Acad Sciences; 2014;111: 1485–1490. doi: 10.1073/pnas.1323736111 24474775
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 1485-1490
    • Cukalac, T.1    Chadderton, J.2    Handel, A.3    Doherty, P.C.4    Turner, S.J.5    Thomas, P.G.6
  • 66
    • 78650983452 scopus 로고    scopus 로고
    • Interferon limits the effectiveness of melanoma peptide vaccines
    • Cho HI, Lee YR, Celis E, Interferon limits the effectiveness of melanoma peptide vaccines. Blood. 2011;117: 135–144. doi: 10.1182/blood-2010-08-298117 20889921
    • (2011) Blood , vol.117 , pp. 135-144
    • Cho, H.I.1    Lee, Y.R.2    Celis, E.3
  • 67
    • 33745318852 scopus 로고    scopus 로고
    • Secreted proteins from Mycobacterium tuberculosis gain access to the cytosolic MHC class-I antigen-processing pathway
    • Lewinsohn DM, Grotzke JE, Heinzel AS, Zhu L, Ovendale PJ, Johnson M, et al. Secreted proteins from Mycobacterium tuberculosis gain access to the cytosolic MHC class-I antigen-processing pathway. J Immunol. 2006;177: 437–442. 16785540
    • (2006) J Immunol , vol.177 , pp. 437-442
    • Lewinsohn, D.M.1    Grotzke, J.E.2    Heinzel, A.S.3    Zhu, L.4    Ovendale, P.J.5    Johnson, M.6
  • 68
    • 0034234609 scopus 로고    scopus 로고
    • CD8+ CTL from lungs of Mycobacterium tuberculosis-infected mice express perforin in vivo and lyse infected macrophages
    • Serbina NV, Liu CC, Scanga CA, Flynn JL, CD8+ CTL from lungs of Mycobacterium tuberculosis-infected mice express perforin in vivo and lyse infected macrophages. J Immunol. 2000;165: 353–363. 10861072
    • (2000) J Immunol , vol.165 , pp. 353-363
    • Serbina, N.V.1    Liu, C.C.2    Scanga, C.A.3    Flynn, J.L.4
  • 69
    • 79251572061 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccination
    • Woodworth JS, Shin DS, Volman M, Nunes-Alves C, Fortune SM, Behar SM, Mycobacterium tuberculosis directs immunofocusing of CD8+ T cell responses despite vaccination. J Immunol. 2011;186: 1627–1637. doi: 10.4049/jimmunol.1002911 21178003
    • (2011) J Immunol , vol.186 , pp. 1627-1637
    • Woodworth, J.S.1    Shin, D.S.2    Volman, M.3    Nunes-Alves, C.4    Fortune, S.M.5    Behar, S.M.6
  • 70
    • 79958073315 scopus 로고    scopus 로고
    • Suboptimal activation of antigen-specific CD4+ effector cells enables persistence of M. tuberculosis in vivo
    • Bold TD, Banaei N, Wolf AJ, Ernst JD, Ramakrishnan L, Suboptimal activation of antigen-specific CD4+ effector cells enables persistence of M. tuberculosis in vivo. PLoS Pathog. Public Library of Science; 2011;7: e1002063. doi: 10.1371/journal.ppat.1002063 21637811
    • (2011) PLoS Pathog , vol.7 , pp. 1002063
    • Bold, T.D.1    Banaei, N.2    Wolf, A.J.3    Ernst, J.D.4    Ramakrishnan, L.5
  • 71
    • 79956302280 scopus 로고    scopus 로고
    • Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas
    • Egen JG, Rothfuchs AG, Feng CG, Horwitz MA, Sher A, Germain RN, Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas. Immunity. 2011;34: 807–819. doi: 10.1016/j.immuni.2011.03.022 21596592
    • (2011) Immunity , vol.34 , pp. 807-819
    • Egen, J.G.1    Rothfuchs, A.G.2    Feng, C.G.3    Horwitz, M.A.4    Sher, A.5    Germain, R.N.6
  • 72
    • 84953295338 scopus 로고    scopus 로고
    • Suboptimal Antigen Presentation Contributes to Virulence of Mycobacterium tuberculosis In Vivo
    • Grace PS, Ernst JD, Suboptimal Antigen Presentation Contributes to Virulence of Mycobacterium tuberculosis In Vivo. The Journal of Immunology. American Association of Immunologists; 2015;: 1501494. doi: 10.4049/jimmunol.1501494
    • (2015) The Journal of Immunology , pp. 1501494
    • Grace, P.S.1    Ernst, J.D.2
  • 73
    • 84913574402 scopus 로고    scopus 로고
    • Central Memory CD4+ T Cells Are Responsible for the Recombinant Bacillus Calmette-Guérin ΔureC::hly Vaccine's Superior Protection Against Tuberculosis
    • Vogelzang A, Perdomo C, Zedler U, Kuhlmann S, Hurwitz R, Gengenbacher M, et al. Central Memory CD4+ T Cells Are Responsible for the Recombinant Bacillus Calmette-Guérin ΔureC::hly Vaccine's Superior Protection Against Tuberculosis. J INFECT DIS. Oxford University Press; 2014;210: 1928–1937. doi: 10.1093/infdis/jiu347 24943726
    • (2014) J INFECT DIS , vol.210 , pp. 1928-1937
    • Vogelzang, A.1    Perdomo, C.2    Zedler, U.3    Kuhlmann, S.4    Hurwitz, R.5    Gengenbacher, M.6
  • 74
    • 84879105286 scopus 로고    scopus 로고
    • Control of chronic mycobacterium tuberculosis infection by CD4 KLRG1- IL-2-secreting central memory cells
    • Lindenstrøm T, Knudsen NPH, Agger EM, Andersen P, Control of chronic mycobacterium tuberculosis infection by CD4 KLRG1- IL-2-secreting central memory cells. The Journal of Immunology. 2013;190: 6311–6319. doi: 10.4049/jimmunol.1300248 23677471
    • (2013) The Journal of Immunology , vol.190 , pp. 6311-6319
    • Lindenstrøm, T.1    Knudsen, N.P.H.2    Agger, E.M.3    Andersen, P.4
  • 75
    • 79957618772 scopus 로고    scopus 로고
    • Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
    • Hansen SG, Ford JC, Lewis MS, Ventura AB, Hughes CM, Coyne-Johnson L, et al. Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine. Nature. 2011;473: 523–527. doi: 10.1038/nature10003 21562493
    • (2011) Nature , vol.473 , pp. 523-527
    • Hansen, S.G.1    Ford, J.C.2    Lewis, M.S.3    Ventura, A.B.4    Hughes, C.M.5    Coyne-Johnson, L.6
  • 77
    • 84933564632 scopus 로고    scopus 로고
    • A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells
    • Stary G, Olive A, Radovic-Moreno AF, Gondek D, Alvarez D, Basto PA, et al. A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells. Science. 2015;348: aaa8205–aaa8205. doi: 10.1126/science.aaa8205 26089520
    • (2015) Science , vol.348 , pp. 8205
    • Stary, G.1    Olive, A.2    Radovic-Moreno, A.F.3    Gondek, D.4    Alvarez, D.5    Basto, P.A.6
  • 79
    • 84880756431 scopus 로고    scopus 로고
    • Preexisting high frequencies of memory CD8+ T cells favor rapid memory differentiation and preservation of proliferative potential upon boosting
    • Fraser KA, Schenkel JM, Jameson SC, Vezys V, Masopust D, Preexisting high frequencies of memory CD8+ T cells favor rapid memory differentiation and preservation of proliferative potential upon boosting. Immunity. 2013;39: 171–183. doi: 10.1016/j.immuni.2013.07.003 23890070
    • (2013) Immunity , vol.39 , pp. 171-183
    • Fraser, K.A.1    Schenkel, J.M.2    Jameson, S.C.3    Vezys, V.4    Masopust, D.5
  • 81
    • 84900842237 scopus 로고    scopus 로고
    • Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire
    • Lepore M, Kalinichenko A, Kalinicenko A, Colone A, Paleja B, Singhal A, et al. Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire. Nat Commun. 2014;5: 3866. doi: 10.1038/ncomms4866 24832684
    • (2014) Nat Commun , vol.5 , pp. 3866
    • Lepore, M.1    Kalinichenko, A.2    Kalinicenko, A.3    Colone, A.4    Paleja, B.5    Singhal, A.6
  • 83
    • 84883466251 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue
    • Sherwood AM, Emerson RO, Scherer D, Habermann N, Buck K, Staffa J, et al. Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue. Cancer Immunol Immunother. Springer Berlin Heidelberg; 2013;62: 1453–1461. doi: 10.1007/s00262-013-1446-2 23771160
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 1453-1461
    • Sherwood, A.M.1    Emerson, R.O.2    Scherer, D.3    Habermann, N.4    Buck, K.5    Staffa, J.6


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