-
1
-
-
0242268398
-
Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system
-
Stanley, S. A., Raghavan, S., Hwang, W. W. & Cox, J. S. Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system. Proc. Natl Acad. Sci. USA 100, 13001-13006 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 13001-13006
-
-
Stanley, S.A.1
Raghavan, S.2
Hwang, W.W.3
Cox, J.S.4
-
2
-
-
0142059794
-
The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue
-
Hsu, T. et al. The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue. Proc. Natl Acad. Sci. USA 100, 12420-12425 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 12420-12425
-
-
Hsu, T.1
-
3
-
-
34249012130
-
Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages
-
Pathak, S. K. et al. Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages. Nature Immunol. 8, 610-618 (2007).
-
(2007)
Nature Immunol
, vol.8
, pp. 610-618
-
-
Pathak, S.K.1
-
4
-
-
35348892037
-
Type VII secretion-mycobacteria show the way
-
Abdallah, A. M. et al. Type VII secretion-mycobacteria show the way. Nature Rev. Microbiol. 5, 883-891 (2007).
-
(2007)
Nature Rev. Microbiol
, vol.5
, pp. 883-891
-
-
Abdallah, A.M.1
-
5
-
-
0942290453
-
Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis
-
Guinn, K. M. et al. Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis. Mol. Microbiol. 51, 359-370 (2004).
-
(2004)
Mol. Microbiol
, vol.51
, pp. 359-370
-
-
Guinn, K.M.1
-
6
-
-
34249870368
-
A genetic screen for Mycobacterium tuberculosis mutants defective for phagosome maturation arrest identifies components of the ESX-1 secretion system
-
MacGurn, J. A. & Cox, J. S. A genetic screen for Mycobacterium tuberculosis mutants defective for phagosome maturation arrest identifies components of the ESX-1 secretion system. Infect. Immun. 75, 2668-2678 (2007).
-
(2007)
Infect. Immun
, vol.75
, pp. 2668-2678
-
-
MacGurn, J.A.1
Cox, J.S.2
-
7
-
-
14044254749
-
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
-
Volkman, H. E. et al. Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant. PLoS Biol. 2, e367 (2004).
-
(2004)
PLoS Biol
, vol.2
-
-
Volkman, H.E.1
-
8
-
-
33847359299
-
The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis
-
Stanley, S. A., Johndrow, J. E., Manzanillo, P.&Cox, J. S. The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis. J. Immunol. 178, 3143-3152 (2007).
-
(2007)
J. Immunol
, vol.178
, pp. 3143-3152
-
-
Stanley, S.A.1
Johndrow, J.E.2
Manzanillo, P.3
Cox, J.S.4
-
9
-
-
34547766513
-
ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membranelysing activity
-
de Jonge, M. I. et al. ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membranelysing activity. J. Bacteriol. 189, 6028-6034 (2007).
-
(2007)
J. Bacteriol
, vol.189
, pp. 6028-6034
-
-
de Jonge, M.I.1
-
10
-
-
0141539435
-
Intracellular expression of Mycobacterium tuberculosis-specific 10-kDa antigen down-regulates macrophage B7.1 expression and nitric oxide release
-
Singh, B., Singh, G., Trajkovic, V. & Sharma, P. Intracellular expression of Mycobacterium tuberculosis-specific 10-kDa antigen down-regulates macrophage B7.1 expression and nitric oxide release. Clin. Exp. Immunol. 134, 70-77 (2003).
-
(2003)
Clin. Exp. Immunol
, vol.134
, pp. 70-77
-
-
Singh, B.1
Singh, G.2
Trajkovic, V.3
Sharma, P.4
-
11
-
-
0033979229
-
ESAT-6 subunit vaccination against Mycobacterium tuberculosis
-
Brandt, L., Elhay, M., Rosenkrands, I., Lindblad, E. B. & Andersen, P. ESAT-6 subunit vaccination against Mycobacterium tuberculosis. Infect. Immun. 68, 791-795 (2000).
-
(2000)
Infect. Immun
, vol.68
, pp. 791-795
-
-
Brandt, L.1
Elhay, M.2
Rosenkrands, I.3
Lindblad, E.B.4
Andersen, P.5
-
12
-
-
0033972623
-
MTSA-10, the product of the Rv3874 gene of Mycobacterium tuberculosis, elicits tuberculosis-specific, delayed-type hypersensitivity in guinea pigs
-
Colangeli, R. et al. MTSA-10, the product of the Rv3874 gene of Mycobacterium tuberculosis, elicits tuberculosis-specific, delayed-type hypersensitivity in guinea pigs. Infect. Immun. 68, 990-993 (2000).
-
(2000)
Infect. Immun
, vol.68
, pp. 990-993
-
-
Colangeli, R.1
-
13
-
-
0035873516
-
Vaccination with the T cell antigen Mtb 8.4 protects against challenge with Mycobacterium tuberculosis
-
Coler, R. N. et al. Vaccination with the T cell antigen Mtb 8.4 protects against challenge with Mycobacterium tuberculosis. J. Immunol. 166, 6227-6235 (2001).
-
(2001)
J. Immunol
, vol.166
, pp. 6227-6235
-
-
Coler, R.N.1
-
14
-
-
33750319222
-
Mucosal administration of Ag85B-ESAT-6 protects against infection with Mycobacterium tuberculosis and boosts prior bacillus Calmette-Guerin immunity
-
Dietrich, J. et al. Mucosal administration of Ag85B-ESAT-6 protects against infection with Mycobacterium tuberculosis and boosts prior bacillus Calmette-Guerin immunity. J. Immunol. 177, 6353-6360 (2006).
-
(2006)
J. Immunol
, vol.177
, pp. 6353-6360
-
-
Dietrich, J.1
-
15
-
-
33748047496
-
Envisioning future strategies for vaccination against tuberculosis
-
Kaufmann, S. H. Envisioning future strategies for vaccination against tuberculosis. Nature Rev. Immunol. 6, 699-704 (2006).
-
(2006)
Nature Rev. Immunol
, vol.6
, pp. 699-704
-
-
Kaufmann, S.H.1
-
16
-
-
0029920827
-
Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis
-
Mahairas, G. G., Sabo, P. J., Hickey, M. J., Singh, D. C. & Stover, C. K. Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis. J. Bacteriol. 178, 1274-1282 (1996).
-
(1996)
J. Bacteriol
, vol.178
, pp. 1274-1282
-
-
Mahairas, G.G.1
Sabo, P.J.2
Hickey, M.J.3
Singh, D.C.4
Stover, C.K.5
-
17
-
-
4644320227
-
A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion
-
Gao, L. Y. et al. A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion. Mol. Microbiol. 53, 1677-1693 (2004).
-
(2004)
Mol. Microbiol
, vol.53
, pp. 1677-1693
-
-
Gao, L.Y.1
-
18
-
-
14544279302
-
A protein secretion pathway critical for Mycobacterium tuberculosis virulence is conserved and functional in Mycobacterium smegmatis
-
Converse, S. E. & Cox, J. S. A protein secretion pathway critical for Mycobacterium tuberculosis virulence is conserved and functional in Mycobacterium smegmatis. J. Bacteriol. 187, 1238-1245 (2005).
-
(2005)
J. Bacteriol
, vol.187
, pp. 1238-1245
-
-
Converse, S.E.1
Cox, J.S.2
-
19
-
-
29644438456
-
Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence
-
Brodin, P. et al. Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence. Infect. Immun. 74, 88-98 (2006).
-
(2006)
Infect. Immun
, vol.74
, pp. 88-98
-
-
Brodin, P.1
-
20
-
-
23044481526
-
Mutually dependent secretion of proteins required for mycobacterial virulence
-
Fortune, S. M. et al. Mutually dependent secretion of proteins required for mycobacterial virulence. Proc. Natl Acad. Sci. USA 102, 10676-10681 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 10676-10681
-
-
Fortune, S.M.1
-
21
-
-
25144441735
-
A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis
-
MacGurn, J. A., Raghavan, S., Stanley, S. A. & Cox, J. S. A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis. Mol. Microbiol. 57, 1653-1663 (2005).
-
(2005)
Mol. Microbiol
, vol.57
, pp. 1653-1663
-
-
MacGurn, J.A.1
Raghavan, S.2
Stanley, S.A.3
Cox, J.S.4
-
22
-
-
0034595501
-
Enhanced genome annotation using structural profiles in the program 3D-PSSM
-
Kelley, L. A., MacCallum, R. M. & Sternberg, M. J. Enhanced genome annotation using structural profiles in the program 3D-PSSM. J. Mol. Biol. 299, 499-520 (2000).
-
(2000)
J. Mol. Biol
, vol.299
, pp. 499-520
-
-
Kelley, L.A.1
MacCallum, R.M.2
Sternberg, M.J.3
-
23
-
-
0030070934
-
Crystallisation of the Bacillus subtilis sporulation inhibitor SinR, complexed with its antagonist, SinI
-
Lewis, R. J., Brannigan, J. A., Smith, I. & Wilkinson, A. J. Crystallisation of the Bacillus subtilis sporulation inhibitor SinR, complexed with its antagonist, SinI. FEBS Lett. 378, 98-100 (1996).
-
(1996)
FEBS Lett
, vol.378
, pp. 98-100
-
-
Lewis, R.J.1
Brannigan, J.A.2
Smith, I.3
Wilkinson, A.J.4
-
24
-
-
35848943478
-
Mycobacterium tuberculosis invasion of macrophages: Linking bacterial gene expression to environmental cues
-
Rohde, K. H., Abramovitch, R. B. & Russell, D. G. Mycobacterium tuberculosis invasion of macrophages: Linking bacterial gene expression to environmental cues. Cell Host Microbe 2, 352-364 (2007).
-
(2007)
Cell Host Microbe
, vol.2
, pp. 352-364
-
-
Rohde, K.H.1
Abramovitch, R.B.2
Russell, D.G.3
-
25
-
-
33748776564
-
C-terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis
-
Champion, P. A., Stanley, S. A., Champion, M. M., Brown, E. J. & Cox, J. S. C-terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis. Science 313, 1632-1636 (2006).
-
(2006)
Science
, vol.313
, pp. 1632-1636
-
-
Champion, P.A.1
Stanley, S.A.2
Champion, M.M.3
Brown, E.J.4
Cox, J.S.5
-
26
-
-
0027724892
-
Sensing structural intermediates in bacterial flagellar assembly by export of a negative regulator
-
Hughes, K. T., Gillen, K. L., Semon, M. J. & Karlinsey, J. E. Sensing structural intermediates in bacterial flagellar assembly by export of a negative regulator. Science 262, 1277-1280 (1993).
-
(1993)
Science
, vol.262
, pp. 1277-1280
-
-
Hughes, K.T.1
Gillen, K.L.2
Semon, M.J.3
Karlinsey, J.E.4
-
27
-
-
20344403312
-
ExsE, a secreted regulator of type III secretion genes in Pseudomonas aeruginosa
-
Rietsch, A., Vallet-Gely, I., Dove, S. L. & Mekalanos, J. J. ExsE, a secreted regulator of type III secretion genes in Pseudomonas aeruginosa. Proc. Natl Acad. Sci. USA 102, 8006-8011 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 8006-8011
-
-
Rietsch, A.1
Vallet-Gely, I.2
Dove, S.L.3
Mekalanos, J.J.4
-
28
-
-
22244459205
-
A secreted regulatory protein couples transcription to the secretory activity of the Pseudomonas aeruginosa type III secretion system
-
Urbanowski, M. L., Lykken, G. L. & Yahr, T. L. A secreted regulatory protein couples transcription to the secretory activity of the Pseudomonas aeruginosa type III secretion system. Proc. Natl Acad. Sci. USA 102, 9930-9935 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 9930-9935
-
-
Urbanowski, M.L.1
Lykken, G.L.2
Yahr, T.L.3
-
29
-
-
20344407810
-
A secreted anti-activator, OspD1, and its chaperone, Spa15, are involved in the control of transcription by the type III secretion apparatus activity in Shigella flexneri
-
Parsot, C. et al. A secreted anti-activator, OspD1, and its chaperone, Spa15, are involved in the control of transcription by the type III secretion apparatus activity in Shigella flexneri. Mol. Microbiol. 56, 1627-1635 (2005).
-
(2005)
Mol. Microbiol
, vol.56
, pp. 1627-1635
-
-
Parsot, C.1
-
30
-
-
0027458469
-
Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation
-
Ensoli, B. et al. Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J. Virol. 67, 277-287 (1993).
-
(1993)
J. Virol
, vol.67
, pp. 277-287
-
-
Ensoli, B.1
-
31
-
-
0036677811
-
Engrailed homeoprotein secretion is a regulated process
-
Maizel, A. et al. Engrailed homeoprotein secretion is a regulated process. Development 129, 3545-3553 (2002).
-
(2002)
Development
, vol.129
, pp. 3545-3553
-
-
Maizel, A.1
-
32
-
-
40349106159
-
Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP
-
Frigui, W. et al. Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP. PLoS Pathog. 4, e33 (2008).
-
(2008)
PLoS Pathog
, vol.4
-
-
Frigui, W.1
-
33
-
-
38849102911
-
Mutation in the transcriptional regulator PhoP contributes to avirulence of Mycobacterium tuberculosis H37Ra strain
-
Lee, J. S. et al. Mutation in the transcriptional regulator PhoP contributes to avirulence of Mycobacterium tuberculosis H37Ra strain. Cell Host Microbe 3, 97-103 (2008).
-
(2008)
Cell Host Microbe
, vol.3
, pp. 97-103
-
-
Lee, J.S.1
-
34
-
-
23244432880
-
Long-term control of Mycobacterium tuberculosis infection is mediated by dynamic immune responses
-
Lazarevic, V., Nolt, D. & Flynn, J. L. Long-term control of Mycobacterium tuberculosis infection is mediated by dynamic immune responses. J. Immunol. 175, 1107-1117 (2005).
-
(2005)
J. Immunol
, vol.175
, pp. 1107-1117
-
-
Lazarevic, V.1
Nolt, D.2
Flynn, J.L.3
-
35
-
-
34247588355
-
tuberculosis Ser/Thr protein kinase D phosphorylates an anti-anti-sigma factor homolog
-
Greenstein, A. E. et al. tuberculosis Ser/Thr protein kinase D phosphorylates an anti-anti-sigma factor homolog. PLoS Pathog. 3, e49 (2007).
-
(2007)
PLoS Pathog
, vol.3
-
-
Greenstein, A.E.1
-
36
-
-
0043142536
-
Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment
-
Schnappinger, D. et al. Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment. J. Exp. Med. 198, 693-704 (2003).
-
(2003)
J. Exp. Med
, vol.198
, pp. 693-704
-
-
Schnappinger, D.1
-
37
-
-
0242268398
-
Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system
-
Stanley, S. A., Raghavan, S., Hwang, W. W. & Cox, J. S. Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system. Proc. Natl Acad. Sci. USA 100, 13001-13006 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 13001-13006
-
-
Stanley, S.A.1
Raghavan, S.2
Hwang, W.W.3
Cox, J.S.4
-
38
-
-
25144441735
-
A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis
-
MacGurn, J. A., Raghavan, S., Stanley, S. A. & Cox, J. S. A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis. Mol. Microbiol. 57, 1653-1663 (2005).
-
(2005)
Mol. Microbiol
, vol.57
, pp. 1653-1663
-
-
MacGurn, J.A.1
Raghavan, S.2
Stanley, S.A.3
Cox, J.S.4
-
39
-
-
34247588355
-
tuberculosis Ser/Thr protein kinase D phosphorylates an anti-anti-sigma factor homolog
-
Greenstein, A. E. et al. tuberculosis Ser/Thr protein kinase D phosphorylates an anti-anti-sigma factor homolog. PLoS Pathog. 3, e49 (2007).
-
(2007)
PLoS Pathog
, vol.3
-
-
Greenstein, A.E.1
-
40
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
Tusher, V. G., Tibshirani, R. & Chu, G. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl Acad. Sci. USA 98, 5116-5121 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
41
-
-
0043142536
-
Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment
-
Schnappinger, D. et al. Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment. J. Exp. Med. 198, 693-704 (2003).
-
(2003)
J. Exp. Med
, vol.198
, pp. 693-704
-
-
Schnappinger, D.1
-
42
-
-
0031726240
-
An inducible expression system permitting the efficient purification of a recombinant antigen from Mycobacterium smegmatis
-
Triccas, J. A., Parish, T., Britton, W. J.&Gicquel, B. An inducible expression system permitting the efficient purification of a recombinant antigen from Mycobacterium smegmatis. FEMS Microbiol. Lett. 167, 151-156 (1998).
-
(1998)
FEMS Microbiol. Lett
, vol.167
, pp. 151-156
-
-
Triccas, J.A.1
Parish, T.2
Britton, W.J.3
Gicquel, B.4
-
43
-
-
0028079877
-
Escherichia coli-mycobacteria shuttle vectors for operon and gene fusions to lacZ: The pJEM series
-
Timm, J., Lim, E. M. & Gicquel, B. Escherichia coli-mycobacteria shuttle vectors for operon and gene fusions to lacZ: The pJEM series. J. Bacteriol. 176, 6749-6753 (1994).
-
(1994)
J. Bacteriol
, vol.176
, pp. 6749-6753
-
-
Timm, J.1
Lim, E.M.2
Gicquel, B.3
-
44
-
-
19744383611
-
Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor
-
Ehrt, S. et al. Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor. Nucleic Acids Res. 33, e21 (2005).
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Ehrt, S.1
|