XTryptophan biosynthesis protects mycobacteria from CD4 T-Cell-mediated Killing

Cell

Volumn 155, Issue 6, 2013, Pages

  Zhang, Yanjia J ^a   Reddy, Manchi C ^b   Ioerger, Thomas R ^b   Rothchild, Alissa C ^c   Dartois, Veronique ^d   Schuster, Brian M ^a   Trauner, Andrej ^a   Wallis, Deeann ^b   Galaviz, Stacy ^b   Huttenhower, Curtis ^a   Sacchettini, James C ^b   Behar, Samuel M ^c   Rubin, Eric J ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRANILIC ACID; GAMMA INTERFERON; TRYPTOPHAN; 2-AMINO-5-FLUOROBENZOIC ACID; 2-AMINO-6-FLUOROBENZOIC ACID; ANTHRANILIC ACID DERIVATIVE; INDOLEAMINE 2,3 DIOXYGENASE; VIRULENCE FACTOR; 2 AMINO 5 FLUOROBENZOIC ACID; 2 AMINO 6 FLUOROBENZOIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUXOTROPHY; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; CD4+ T LYMPHOCYTE; CHLAMYDIA; CONTROLLED STUDY; HOST RESISTANCE; IMMUNE RESPONSE; INTERFERON INDUCTION; LEISHMANIA; LYMPHOCYTE ACTIVATION; MACROPHAGE; MOLECULAR MECHANICS; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; STARVATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; DRUG EFFECTS; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MYCOBACTERIUM SMEGMATIS; PATHOGENICITY; TUBERCULOSIS; DRUG EFFECT;

BACTERIA (MICROORGANISMS); CHLAMYDIA; CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS;

ANIMALS; BIOSYNTHETIC PATHWAYS; CD4-POSITIVE T-LYMPHOCYTES; HUMANS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INTERFERON-GAMMA; MACROPHAGES; MICE; MICE, INBRED C57BL; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; ORTHO-AMINOBENZOATES; TRYPTOPHAN; TUBERCULOSIS; VIRULENCE FACTORS;

EID: 84890037649     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2013.10.045     Document Type: Article

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