-
1
-
-
0031733687
-
The mabA gene from the inhA operon of Mycobacterium tuberculosis encodes a 3-ketoacyl reductase that fails to confer isoniazid resistance
-
Banerjee, A., M. Sugantino, J. C. Sacchettini, and W. R. Jacobs. 1998. The mabA gene from the inhA operon of Mycobacterium tuberculosis encodes a 3-ketoacyl reductase that fails to confer isoniazid resistance. Microbiology 144:2697-2704.
-
(1998)
Microbiology
, vol.144
, pp. 2697-2704
-
-
Banerjee, A.1
Sugantino, M.2
Sacchettini, J.C.3
Jacobs, W.R.4
-
2
-
-
0041922652
-
Signature gene expression profiles discriminate between isoniazid-, thiolactomycin-, and triclosan-treated Mycobacterium tuberculosis
-
Betts, J. C., A. McLaren, M. G. Lennon, F. M. Kelly, P. T. Lukey, S. J. Blakemore, and K. Duncan. 2003. Signature gene expression profiles discriminate between isoniazid-, thiolactomycin-, and triclosan-treated Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 47:2903-2913.
-
(2003)
Antimicrob. Agents Chemother
, vol.47
, pp. 2903-2913
-
-
Betts, J.C.1
McLaren, A.2
Lennon, M.G.3
Kelly, F.M.4
Lukey, P.T.5
Blakemore, S.J.6
Duncan, K.7
-
3
-
-
2442466919
-
Arylamine N-acetyltransferase is required for synthesis of mycolic acids and complex lipids in Mycobacterium bovis BCG and represents a novel drug target
-
Bhakta, S., G. S. Besra, A. M. Upton, T. Parish, C. Sholto-Douglas-Vernon, K. J. C. Gibson, S. Knutton, S. Gordon, R. P. daSilva, M. C. Anderton, and E. Sim. 2004. Arylamine N-acetyltransferase is required for synthesis of mycolic acids and complex lipids in Mycobacterium bovis BCG and represents a novel drug target. J. Exp. Med. 199:1191-1199.
-
(2004)
J. Exp. Med
, vol.199
, pp. 1191-1199
-
-
Bhakta, S.1
Besra, G.S.2
Upton, A.M.3
Parish, T.4
Sholto-Douglas-Vernon, C.5
Gibson, K.J.C.6
Knutton, S.7
Gordon, S.8
daSilva, R.P.9
Anderton, M.C.10
Sim, E.11
-
4
-
-
27744492218
-
Conditional depletion of KasA, a key enzyme of mycolic acid biosynthesis, leads to mycobacterial cell lysis
-
Bhatt, A., L. Kremer, A. Z. Dai, J. C. Sacchettini, and W. R. Jacobs. 2005. Conditional depletion of KasA, a key enzyme of mycolic acid biosynthesis, leads to mycobacterial cell lysis. J. Bacteriol. 187:7596-7606.
-
(2005)
J. Bacteriol
, vol.187
, pp. 7596-7606
-
-
Bhatt, A.1
Kremer, L.2
Dai, A.Z.3
Sacchettini, J.C.4
Jacobs, W.R.5
-
5
-
-
0037844364
-
Structure, function, and biogenesis of the cell wall of Mycobacterium tuberculosis
-
Brennan, P. J. 2003. Structure, function, and biogenesis of the cell wall of Mycobacterium tuberculosis. Tuberculosis 83:91-97.
-
(2003)
Tuberculosis
, vol.83
, pp. 91-97
-
-
Brennan, P.J.1
-
6
-
-
0036774642
-
Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv
-
Camus, J. C., M. J. Pryor, C. Medigue, and S. T. Cole. 2002. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Microbiology 148:2967-2973.
-
(2002)
Microbiology
, vol.148
, pp. 2967-2973
-
-
Camus, J.C.1
Pryor, M.J.2
Medigue, C.3
Cole, S.T.4
-
7
-
-
0032508046
-
-
Cole, S. T., R. Brosch, J. Parkhill, T. Garnier, C. Churcher, D. Harris, S. V. Gordon, K. Eiglmeier, S. Gas, C. E. Barry, F. Tekaia, K. Badcock, D. Basham, D. Brown, T. Chillingworth, R. Connor, R. Davies, K. Devlin, T. Feltwell, S. Gentles, N. Hamlin, S. Holroyd, T. Hornby, K. Jagels, A. Krogh, J. McLean, S. Moule, L. Murphy, K. Oliver, J. Osborne, M. A. Quail, M. A. Rajandream, J. Rogers, S. Rutter, K. Seeger, J. Skelton, R. Squares, S. Squares, J. E. Sulston, K. Taylor, S. Whitehead, and B. G. Barrell. 1998. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393:537-544.
-
Cole, S. T., R. Brosch, J. Parkhill, T. Garnier, C. Churcher, D. Harris, S. V. Gordon, K. Eiglmeier, S. Gas, C. E. Barry, F. Tekaia, K. Badcock, D. Basham, D. Brown, T. Chillingworth, R. Connor, R. Davies, K. Devlin, T. Feltwell, S. Gentles, N. Hamlin, S. Holroyd, T. Hornby, K. Jagels, A. Krogh, J. McLean, S. Moule, L. Murphy, K. Oliver, J. Osborne, M. A. Quail, M. A. Rajandream, J. Rogers, S. Rutter, K. Seeger, J. Skelton, R. Squares, S. Squares, J. E. Sulston, K. Taylor, S. Whitehead, and B. G. Barrell. 1998. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393:537-544.
-
-
-
-
8
-
-
0032452982
-
The envelope layers of mycobacteria with reference to their pathogenicity
-
Daffe, M., and P. Draper. 1998. The envelope layers of mycobacteria with reference to their pathogenicity. Adv. Microb. Physiol. 39:131-203.
-
(1998)
Adv. Microb. Physiol
, vol.39
, pp. 131-203
-
-
Daffe, M.1
Draper, P.2
-
9
-
-
0021035163
-
Intérêt taxonomique des acides gras des Mycobactéries: Proposition d'une méthode d'analyse
-
Daffe, M., M.-A. Lanéelle, C. Asselineau, V. Lévy-Frébault, and H. L. David. 1983. Intérêt taxonomique des acides gras des Mycobactéries: proposition d'une méthode d'analyse. Ann. Microbiol. Inst. Pasteur 134:241-256.
-
(1983)
Ann. Microbiol. Inst. Pasteur
, vol.134
, pp. 241-256
-
-
Daffe, M.1
Lanéelle, M.-A.2
Asselineau, C.3
Lévy-Frébault, V.4
David, H.L.5
-
10
-
-
0023716154
-
Tetraenoic and pentaenoic mycolic acids from Mycobacterium thamnopheos. Structure, taxonomic and biosynthetic implications
-
Daffé, M., M.-A. Lanéelle, and P. L. Valero-Guillen. 1988. Tetraenoic and pentaenoic mycolic acids from Mycobacterium thamnopheos. Structure, taxonomic and biosynthetic implications. Eur. J. Biochem. 177:339-344.
-
(1988)
Eur. J. Biochem
, vol.177
, pp. 339-344
-
-
Daffé, M.1
Lanéelle, M.-A.2
Valero-Guillen, P.L.3
-
11
-
-
0347361707
-
In vitro inhibition of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA by isoniazid
-
Ducasse-Cabanot, S., M. Cohen-Gonsaud, H. Marrakchi, M. Nguyen, D. Zerbib, J. Bernadou, M. Daffe, G. Labesse, and A. Quemard. 2004. In vitro inhibition of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA by isoniazid. Antimicrob. Agents Chemother. 48:242-249.
-
(2004)
Antimicrob. Agents Chemother
, vol.48
, pp. 242-249
-
-
Ducasse-Cabanot, S.1
Cohen-Gonsaud, M.2
Marrakchi, H.3
Nguyen, M.4
Zerbib, D.5
Bernadou, J.6
Daffe, M.7
Labesse, G.8
Quemard, A.9
-
12
-
-
0021744394
-
Inhibition of fatty acid synthesis by the antibiotic thiolactomycin
-
Hayashi, T., O. Yamamoto, H. Sasaki, H. okazaki, and A. Kawaguchi. 1984. Inhibition of fatty acid synthesis by the antibiotic thiolactomycin. J. Antibiot. 37:1456-1461.
-
(1984)
J. Antibiot
, vol.37
, pp. 1456-1461
-
-
Hayashi, T.1
Yamamoto, O.2
Sasaki, H.3
okazaki, H.4
Kawaguchi, A.5
-
13
-
-
0028960179
-
Missense mutations in the catalase-peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis
-
Heym, B., P. M. Alzari, N. Honore, and S. T. Cole. 1995. Missense mutations in the catalase-peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis. Mol. Microbiol. 15:235-245.
-
(1995)
Mol. Microbiol
, vol.15
, pp. 235-245
-
-
Heym, B.1
Alzari, P.M.2
Honore, N.3
Cole, S.T.4
-
14
-
-
0032982736
-
Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope
-
Jackson, M., C. Raynaud, M. A. Laneelle, C. Guilhot, C. LaurentWinter, D. Ensergueix, B. Gicquel, and M. Daffe. 1999. Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope. Mol. Microbiol. 31:1573-1587.
-
(1999)
Mol. Microbiol
, vol.31
, pp. 1573-1587
-
-
Jackson, M.1
Raynaud, C.2
Laneelle, M.A.3
Guilhot, C.4
LaurentWinter, C.5
Ensergueix, D.6
Gicquel, B.7
Daffe, M.8
-
15
-
-
0034595879
-
Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis
-
Kremer, L., J. D. Douglas, A. Baulard, C. Morehouse, M. R. Guy, D. Alland, L. G. Dover, J. H. Lakey, W. R. Jacobs, P. J. Brennan, D. E. Minnikin, and G. S. Besra. 2000. Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis. J. Biol. Chem. 275:16857-16864.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 16857-16864
-
-
Kremer, L.1
Douglas, J.D.2
Baulard, A.3
Morehouse, C.4
Guy, M.R.5
Alland, D.6
Dover, L.G.7
Lakey, J.H.8
Jacobs, W.R.9
Brennan, P.J.10
Minnikin, D.E.11
Besra, G.S.12
-
16
-
-
1542286897
-
Isolation and characterization of β-ketoacyl-acyl carrier protein reductase (fabG) mutants of Escherichia coli and Salmonella enterica serovar Typhimurium
-
Lai, C.-Y., and J. E. Cronan. 2004. Isolation and characterization of β-ketoacyl-acyl carrier protein reductase (fabG) mutants of Escherichia coli and Salmonella enterica serovar Typhimurium. J. Bacteriol. 186:1869-1878.
-
(2004)
J. Bacteriol
, vol.186
, pp. 1869-1878
-
-
Lai, C.-Y.1
Cronan, J.E.2
-
17
-
-
0035884299
-
Accurate molecular mass determination of mycolic acids by MALDI-TOF mass spectrometry
-
Laval, F., M. A. Laneelle, C. Deon, B. Monsarrat, and M. Daffe. 2001. Accurate molecular mass determination of mycolic acids by MALDI-TOF mass spectrometry. Anal. Chem. 73:4537-4544.
-
(2001)
Anal. Chem
, vol.73
, pp. 4537-4544
-
-
Laval, F.1
Laneelle, M.A.2
Deon, C.3
Monsarrat, B.4
Daffe, M.5
-
18
-
-
0033616584
-
A mutant of Mycobacterium smegmatis defective in the biosynthesis of mycolic acids accumulates meromycolates
-
Liu, J., and H. Nikaido. 1999. A mutant of Mycobacterium smegmatis defective in the biosynthesis of mycolic acids accumulates meromycolates. Proc. Natl. Acad. Sci. USA 96:4011-4016.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4011-4016
-
-
Liu, J.1
Nikaido, H.2
-
19
-
-
0031820470
-
Site-directed mutagenesis of the 19-kilodalton lipoprotein antigen reveals no essential role for the protein in the growth and virulence of Mycobacterium intracellulare
-
Mahenthiralingam, E., B. I. Marklund, L. A. Brooks, D. A. Smith, G. J. Bancroft, and R. W. Stokes. 1998. Site-directed mutagenesis of the 19-kilodalton lipoprotein antigen reveals no essential role for the protein in the growth and virulence of Mycobacterium intracellulare. Infect. Immun. 66:3626-3634.
-
(1998)
Infect. Immun
, vol.66
, pp. 3626-3634
-
-
Mahenthiralingam, E.1
Marklund, B.I.2
Brooks, L.A.3
Smith, D.A.4
Bancroft, G.J.5
Stokes, R.W.6
-
20
-
-
0036228187
-
MabA (FabG1), a Mycobacterium tuberculosis protein involved in the long-chain fatty acid elongation system FAS-II
-
Marrakchi, H., S. Ducasse, G. Labesse, H. Montrozier, E. Margeat, L. Emorine, X. Charpentier, M. Daffe, and A. Quemard. 2002. MabA (FabG1), a Mycobacterium tuberculosis protein involved in the long-chain fatty acid elongation system FAS-II. Microbiology 148:951-960.
-
(2002)
Microbiology
, vol.148
, pp. 951-960
-
-
Marrakchi, H.1
Ducasse, S.2
Labesse, G.3
Montrozier, H.4
Margeat, E.5
Emorine, L.6
Charpentier, X.7
Daffe, M.8
Quemard, A.9
-
21
-
-
17644436310
-
Inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis, by triclosan and isoniazid
-
Parikh, S. L., G. Xiao, and P. J. Tonge. 2000. Inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis, by triclosan and isoniazid. Biochemistry 39:7645-7650.
-
(2000)
Biochemistry
, vol.39
, pp. 7645-7650
-
-
Parikh, S.L.1
Xiao, G.2
Tonge, P.J.3
-
22
-
-
17844394673
-
HemZ is essential for the growth of Mycobacterium tuberculosis
-
Parish, T., M. Schaeffer, G. Roberts, and K. Duncan. 2005. HemZ is essential for the growth of Mycobacterium tuberculosis. Tuberculosis 85:197-204.
-
(2005)
Tuberculosis
, vol.85
, pp. 197-204
-
-
Parish, T.1
Schaeffer, M.2
Roberts, G.3
Duncan, K.4
-
23
-
-
0033880508
-
Use of a flexible cassette method to generate a double unmarked Mycobacterium tuberculosis tlyA plcABC mutant by gene replacement
-
Parish, T., and N. G. Stoker. 2000. Use of a flexible cassette method to generate a double unmarked Mycobacterium tuberculosis tlyA plcABC mutant by gene replacement. Microbiology 146:1969-1975.
-
(2000)
Microbiology
, vol.146
, pp. 1969-1975
-
-
Parish, T.1
Stoker, N.G.2
-
24
-
-
0348110537
-
Efficient switching of mycobacteriophage L5-based integrating plasmids in Mycobacterium tuberculosis
-
Pashley, C. A., and T. Parish. 2003. Efficient switching of mycobacteriophage L5-based integrating plasmids in Mycobacterium tuberculosis. FEMS Microbiol. Lett. 229:211-215.
-
(2003)
FEMS Microbiol. Lett
, vol.229
, pp. 211-215
-
-
Pashley, C.A.1
Parish, T.2
-
25
-
-
0345701347
-
Genes required for mycobacterial growth defined by high density mutagenesis
-
Sassetti, C. M., D. H. Boyd, and E. J. Rubin. 2003. Genes required for mycobacterial growth defined by high density mutagenesis. Mol. Microbiol. 48:77-84.
-
(2003)
Mol. Microbiol
, vol.48
, pp. 77-84
-
-
Sassetti, C.M.1
Boyd, D.H.2
Rubin, E.J.3
-
26
-
-
0035861550
-
Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB
-
Schaeffer, M. L., G. Agnihotri, C. Volker, H. Kallender, P. J. Brennan, and J. T. Lonsdale. 2001. Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB. J. Biol. Chem. 276:47029-47037.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 47029-47037
-
-
Schaeffer, M.L.1
Agnihotri, G.2
Volker, C.3
Kallender, H.4
Brennan, P.J.5
Lonsdale, J.T.6
-
27
-
-
0029806578
-
Antimycobacterial action of thiolactomycin: An inhibitor of fatty acid and mycolic acid synthesis
-
Slayden, R. A., R. E. Lee, J. W. Armour, A. M. Cooper, I. M. Orme, P. J. Brennan, and G. S. Besra. 1996. Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis. Antimicrob. Agents Chemother. 40:2813-2819.
-
(1996)
Antimicrob. Agents Chemother
, vol.40
, pp. 2813-2819
-
-
Slayden, R.A.1
Lee, R.E.2
Armour, J.W.3
Cooper, A.M.4
Orme, I.M.5
Brennan, P.J.6
Besra, G.S.7
-
28
-
-
0025922291
-
New use of BCG for recombinant vaccines
-
Stover, C. K., V. F. Delacruz, T. R. Fuerst, J. E. Burlein, L. A. Benson, L. T. Bennett, G. P. Bansal, J. F. Young, M. H. Lee, G. F. Hatfull, S. B. Snapper, R. G. Barletta, W. R. Jacobs, and B. R. Bloom. 1991. New use of BCG for recombinant vaccines. Nature 351:456-460.
-
(1991)
Nature
, vol.351
, pp. 456-460
-
-
Stover, C.K.1
Delacruz, V.F.2
Fuerst, T.R.3
Burlein, J.E.4
Benson, L.A.5
Bennett, L.T.6
Bansal, G.P.7
Young, J.F.8
Lee, M.H.9
Hatfull, G.F.10
Snapper, S.B.11
Barletta, R.G.12
Jacobs, W.R.13
Bloom, B.R.14
-
29
-
-
12844278679
-
Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis
-
Takayama, K., C. Wang, and G. S. Besra. 2005. Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin. Microbiol. Rev. 18:81-101.
-
(2005)
Clin. Microbiol. Rev
, vol.18
, pp. 81-101
-
-
Takayama, K.1
Wang, C.2
Besra, G.S.3
-
30
-
-
9644257517
-
Protein-protein interactions within the fatty acid synthase-II system of Mycobacterium tuberculosis are essential for mycobacterial viability
-
Veyron-Churlet, R., O. Guerrini, L. Mourey, M. Daffe, and D. Zerbib. 2004. Protein-protein interactions within the fatty acid synthase-II system of Mycobacterium tuberculosis are essential for mycobacterial viability. Mol. Microbiol. 54:1161-1172.
-
(2004)
Mol. Microbiol
, vol.54
, pp. 1161-1172
-
-
Veyron-Churlet, R.1
Guerrini, O.2
Mourey, L.3
Daffe, M.4
Zerbib, D.5
-
31
-
-
0038410325
-
Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis
-
Vilcheze, C., H. R. Morbidoni, T. R. Weisbrod, H. Iwamoto, M. Kuo, J. C. Sacchettini, and W. R. Jacobs. 2000. Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis. J. Bacteriol. 182:4059-4067.
-
(2000)
J. Bacteriol
, vol.182
, pp. 4059-4067
-
-
Vilcheze, C.1
Morbidoni, H.R.2
Weisbrod, T.R.3
Iwamoto, H.4
Kuo, M.5
Sacchettini, J.C.6
Jacobs, W.R.7
-
32
-
-
0018648998
-
The major mycolic acids of Mycobacterium smegmatis
-
Wong, M. Y. H., P. A. Steck, and G. R. Gray. 1979. The major mycolic acids of Mycobacterium smegmatis. J. Biol. Chem. 5734-5740.
-
(1979)
J. Biol. Chem
, pp. 5734-5740
-
-
Wong, M.Y.H.1
Steck, P.A.2
Gray, G.R.3
-
33
-
-
0027211111
-
Transformation with katG restores isoniazid-sensitivity in Mycobacterium tuberculosis isolates resistant to a range of drug concentrations
-
Zhang, Y., T. Garbe, and D. Young. 1993. Transformation with katG restores isoniazid-sensitivity in Mycobacterium tuberculosis isolates resistant to a range of drug concentrations. Mol. Microbiol. 8:521-524.
-
(1993)
Mol. Microbiol
, vol.8
, pp. 521-524
-
-
Zhang, Y.1
Garbe, T.2
Young, D.3
-
34
-
-
0028090438
-
Strain variation in the katG region of Mycobacterium tuberculosis
-
Zhang, Y., and D. Young. 1994. Strain variation in the katG region of Mycobacterium tuberculosis. Mol. Microbiol. 14:301-308.
-
(1994)
Mol. Microbiol
, vol.14
, pp. 301-308
-
-
Zhang, Y.1
Young, D.2
|