Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of Mycobacterium tuberculosis

Biochemical Journal

Volumn 367, Issue 1, 2002, Pages 279-285

  Choudhuri, Baisakhee Saha ^a   Bhakta, Sanjib ^a   Barik, Rajib ^a   Basu, Joyoti ^a   Kundu, Manikuntala ^a   Chakrabarti, Parul ^a  

^a BOSE INSTITUTE   (India)

Author keywords

Antibiotic resistance; Efflux pump; Lipid transporter; Mycobacteria; Virulence

Indexed keywords

ADENOSINETRIPHOSPHATE; ANTIBIOTICS; CHARACTERIZATION; ENZYME INHIBITION; ESCHERICHIA COLI; GENES; POLYPEPTIDES; PROTEINS; SUBSTRATES;

RESISTANT PHENOTYPES;

BIOCHEMISTRY;

2',7' BIS(2 CARBOXYETHYL) 5(6) CARBOXYFLUORESCEIN; 2,7 BIS(CARBOXYETHYL) 6 CARBOXYFLUORESCEIN; ABC TRANSPORTER; ANTIBIOTIC AGENT; CATION; CHLORAMPHENICOL; DAUNORUBICIN; DOXORUBICIN; ERYTHROMYCIN; ETHAMBUTOL; ETHIDIUM BROMIDE; GENE PRODUCT; NORFLOXACIN; PUROMYCIN; RESERPINE; STREPTOMYCIN; TETRACYCLINE; UNCLASSIFIED DRUG; VERAPAMIL; ADENOSINE TRIPHOSPHATE; ADRENERGIC RECEPTOR AFFECTING AGENT; ANTINEOPLASTIC ANTIBIOTIC; BACTERIAL PROTEIN; CALCIUM CHANNEL BLOCKING AGENT; DNA BINDING PROTEIN; DRRA PROTEIN, BACTERIA; DRRB PROTEIN, MYCOBACTERIUM TUBERCULOSIS;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL MEMBRANE; CONTROLLED STUDY; DRRA GENE; DRRB GENE; DRUG UPTAKE; ESCHERICHIA COLI; GENE OVEREXPRESSION; GENETIC CODE; GENOME; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; AMINO ACID SEQUENCE; BIOSYNTHESIS; CHEMISTRY; DOSE RESPONSE; DRUG RESISTANCE; GENETICS; LIPID METABOLISM; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

MYCOBACTERIUM TUBERCULOSIS;

ADENOSINE TRIPHOSPHATE; ADRENERGIC UPTAKE INHIBITORS; AMINO ACID SEQUENCE; ANTIBIOTICS, ANTINEOPLASTIC; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL PROTEINS; BASE SEQUENCE; BIOLOGICAL TRANSPORT; CALCIUM CHANNEL BLOCKERS; CLONING, MOLECULAR; DAUNORUBICIN; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG RESISTANCE; ESCHERICHIA COLI; LIPID METABOLISM; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; RESERPINE; VERAPAMIL;

EID: 0036796243     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020615     Document Type: Article

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