The MarR family transcription factor Rv1404 coordinates adaptation of Mycobacterium tuberculosis to acid stress via controlled expression of Rv1405c, a virulence-associated methyltransferase

Tuberculosis

Volumn 97, Issue , 2016, Pages 154-162

  Healy, Claire ^a,d   Golby, Paul ^b,e   MacHugh, David E ^a   Gordon, Stephen V ^a,c  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b VETERINARY LABORATORIES AGENCY   (United Kingdom)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

^e NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Acid stress; Mycobacteriun tuberculosis; Transcriptional regulation; Virulence

Indexed keywords

METHYLTRANSFERASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RV1404; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; DNA BINDING PROTEIN; MARR-FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN, MYCOBACTERIUM;

ACIDITY; ARTICLE; ASSAY; BACTERIAL VIRULENCE; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE; GENE EXPRESSION; GENE FUNCTION; IN VITRO STUDY; MUTANT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REPRESSOR GENE; ADAPTATION; CHROMATIN IMMUNOPRECIPITATION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; GENOTYPE; GROWTH, DEVELOPMENT AND AGING; HOST PATHOGEN INTERACTION; METABOLISM; MUTATION; PATHOGENICITY; PH; PHENOTYPE; PHYSIOLOGICAL STRESS; VIRULENCE;

ADAPTATION, PHYSIOLOGICAL; BACTERIAL PROTEINS; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION, BACTERIAL; GENOTYPE; HOST-PATHOGEN INTERACTIONS; HYDROGEN-ION CONCENTRATION; METHYLTRANSFERASES; MUTATION; MYCOBACTERIUM TUBERCULOSIS; PHENOTYPE; POLYMERASE CHAIN REACTION; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; VIRULENCE;

EID: 84960421904     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2015.10.003     Document Type: Article

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