-
1
-
-
84856425976
-
-
American Cancer Society American Cancer Society
-
American Cancer Society. Global Cancer Facts & Figures 3rd edn (American Cancer Society, 2015).
-
(2015)
Global Cancer Facts & Figures 3rd Edn
-
-
-
2
-
-
85003815084
-
Small-cell lung cancer in 2016: Shining light on novel targets and therapies
-
Rudin, C. M. & Poirier, J. T. Small-cell lung cancer in 2016: shining light on novel targets and therapies. Nat. Rev. Clin. Oncol. 14, 75-76 (2017).
-
(2017)
Nat. Rev. Clin. Oncol.
, vol.14
, pp. 75-76
-
-
Rudin, C.M.1
Poirier, J.T.2
-
3
-
-
84994470617
-
Mutational signatures associated with tobacco smoking in human cancer
-
Alexandrov, L. B. et al. Mutational signatures associated with tobacco smoking in human cancer. Science 354, 618-622 (2016).
-
(2016)
Science
, vol.354
, pp. 618-622
-
-
Alexandrov, L.B.1
-
4
-
-
84938132350
-
Comprehensive genomic profiles of small cell lung cancer
-
George, J. et al. Comprehensive genomic profiles of small cell lung cancer. Nature 524, 47-53 (2015).
-
(2015)
Nature
, vol.524
, pp. 47-53
-
-
George, J.1
-
5
-
-
84962812153
-
Small cell lung cancer: Can recent advances in biology and molecular biology be translated into improved outcomes?
-
Bunn, P. A. Jr et al. Small cell lung cancer: can recent advances in biology and molecular biology be translated into improved outcomes? J. Thorac Oncol. 11, 453-474 (2016).
-
(2016)
J. Thorac Oncol.
, vol.11
, pp. 453-474
-
-
Bunn, P.A.1
-
6
-
-
7344228962
-
Second primary tumours in more than 2-year disease-free survivors of small-cell lung cancer in Japan: The role of smoking cessation
-
Kawahara, M. et al. Second primary tumours in more than 2-year disease-free survivors of small-cell lung cancer in Japan: the role of smoking cessation. Br. J. Cancer 78, 409-412 (1998).
-
(1998)
Br. J. Cancer
, vol.78
, pp. 409-412
-
-
Kawahara, M.1
-
7
-
-
84950132486
-
Lung cancer statistics
-
Torre, L. A., Siegel, R. L. & Jemal, A. Lung cancer statistics. Adv. Exp. Med. Biol. 893, 1-19 (2016).
-
(2016)
Adv. Exp. Med. Biol.
, vol.893
, pp. 1-19
-
-
Torre, L.A.1
Siegel, R.L.2
Jemal, A.3
-
8
-
-
85034864658
-
-
Cancer Research UK. Lung cancer incidence statistics. Cancer Research UK
-
Cancer Research UK. Lung cancer incidence statistics. Cancer Research UK http://www.cancerresearchuk. org/health-professional/cancer-statistics/statistics-by-cancer-type/lung-cancer/incidence (2014).
-
(2014)
-
-
-
9
-
-
85034862392
-
Current status of small cell lung cancer in China
-
Liu, J., Cheng, Y., Li, H. & Zhang, S. Current status of small cell lung cancer in China. J. Cancer Biol. Res. 2, 1032 (2014).
-
(2014)
J. Cancer Biol. Res.
, vol.2
, pp. 1032
-
-
Liu, J.1
Cheng, Y.2
Li, H.3
Zhang, S.4
-
10
-
-
84907986013
-
US lung cancer trends by histologic type
-
Lewis, D. R., Check, D. P., Caporaso, N. E., Travis, W. D. & Devesa, S. S. US lung cancer trends by histologic type. Cancer 120, 2883-2892 (2014).
-
(2014)
Cancer
, vol.120
, pp. 2883-2892
-
-
Lewis, D.R.1
Check, D.P.2
Caporaso, N.E.3
Travis, W.D.4
Devesa, S.S.5
-
11
-
-
84964350752
-
Epidemiology of Lung cancer in Korea: Recent trends
-
Park, J. Y. & Jang, S. H. Epidemiology of Lung cancer in Korea: recent trends. Tuberc Respir. Dis. 79, 58-69 (2016).
-
(2016)
Tuberc Respir. Dis.
, vol.79
, pp. 58-69
-
-
Park, J.Y.1
Jang, S.H.2
-
12
-
-
33750603100
-
Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: Analysis of the surveillance, epidemiologic, and end results database
-
Govindan, R. et al. Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database. J. Clin. Oncol. 24, 4539-4544 (2006).
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 4539-4544
-
-
Govindan, R.1
-
13
-
-
85034864787
-
-
US Congress. H.R.733-Recalcitrant Cancer Research Act of 2012. Congress.gov
-
US Congress. H.R.733-Recalcitrant Cancer Research Act of 2012. Congress.gov https://www.congress.gov/bill/112th-congress/house-bill/733 (2012).
-
(2012)
-
-
-
14
-
-
0001248220
-
The nature of the "oat celled" sarcoma of the mediastinum
-
Barnard, W. The nature of the "oat celled" sarcoma of the mediastinum. J. Pathol. Bacteriol. 29, 241-244 (1926).
-
(1926)
J. Pathol. Bacteriol.
, vol.29
, pp. 241-244
-
-
Barnard, W.1
-
15
-
-
0000513167
-
Oat-cell carcinoma of the bronchus
-
Azzopardi, J. G. Oat-cell carcinoma of the bronchus. J. Pathol. Bacteriol. 78, 513-519 (1959).
-
(1959)
J. Pathol. Bacteriol.
, vol.78
, pp. 513-519
-
-
Azzopardi, J.G.1
-
16
-
-
67651068682
-
The epidemiology and survival of extrapulmonary small cell carcinoma in South East England, 1970-2004
-
Wong, Y. N., Jack, R. H., Mak, V., Henrik, M. & Davies, E. A. The epidemiology and survival of extrapulmonary small cell carcinoma in South East England, 1970-2004. BMC Cancer 9, 209 (2009).
-
(2009)
BMC Cancer
, vol.9
, pp. 209
-
-
Wong, Y.N.1
Jack, R.H.2
Mak, V.3
Henrik, M.4
Davies, E.A.5
-
17
-
-
0015890021
-
Frequency of residual and metastatic tumor in patients undergoing curative surgical resection for lung cancer
-
Matthews, M. J., Kanhouwa, S., Pickren, J. & Robinette, D. Frequency of residual and metastatic tumor in patients undergoing curative surgical resection for lung cancer. Cancer Chemother. Rep. 3 4, 63-67 (1973).
-
(1973)
Cancer Chemother. Rep.
, vol.34
, pp. 63-67
-
-
Matthews, M.J.1
Kanhouwa, S.2
Pickren, J.3
Robinette, D.4
-
18
-
-
0014375114
-
Oat-cell carcinoma of the lung. Its origin and relationship to bronchial carcinoid
-
Bensch, K. G., Corrin, B., Pariente, R. & Spencer, H. Oat-cell carcinoma of the lung. Its origin and relationship to bronchial carcinoid. Cancer 22, 1163-1172 (1968).
-
(1968)
Cancer
, vol.22
, pp. 1163-1172
-
-
Bensch, K.G.1
Corrin, B.2
Pariente, R.3
Spencer, H.4
-
19
-
-
0014007530
-
5-Hydroxytryptophan uptake by dog thyroid 'C' cells, and its possible significance in polypeptide hormone production
-
Pearse, A. G. 5-Hydroxytryptophan uptake by dog thyroid 'C' cells, and its possible significance in polypeptide hormone production. Nature 211, 598-600 (1966).
-
(1966)
Nature
, vol.211
, pp. 598-600
-
-
Pearse, A.G.1
-
20
-
-
0022855207
-
The diffuse neuroendocrine system: Peptides, amines, placodes and the APUD theory
-
Pearse, A. G. The diffuse neuroendocrine system: peptides, amines, placodes and the APUD theory. Prog. Brain Res. 68, 25-31 (1986).
-
(1986)
Prog. Brain Res.
, vol.68
, pp. 25-31
-
-
Pearse, A.G.1
-
21
-
-
0025347331
-
"aPUD" cells: Fact and fiction
-
Baylin, S. B. "APUD" cells: fact and fiction. Trends Endocrinol. Metab. 1, 198-204 (1990).
-
(1990)
Trends Endocrinol. Metab.
, vol.1
, pp. 198-204
-
-
Baylin, S.B.1
-
22
-
-
79953306029
-
The origin of neuroendocrine tumors and the neural crest saga
-
Rosai, J. The origin of neuroendocrine tumors and the neural crest saga. Mod. Pathol. 24, S53-S57 (2011).
-
(2011)
Mod. Pathol.
, vol.24
, pp. S53-S57
-
-
Rosai, J.1
-
23
-
-
0018954542
-
Establishment of continuous, clonable cultures of small-cell carcinoma of lung which have amine precursor uptake and decarboxylation cell properties
-
Gazdar, A. F. et al. Establishment of continuous, clonable cultures of small-cell carcinoma of lung which have amine precursor uptake and decarboxylation cell properties. Cancer Res. 40, 3502-3507 (1980).
-
(1980)
Cancer Res.
, vol.40
, pp. 3502-3507
-
-
Gazdar, A.F.1
-
24
-
-
84989936333
-
ASCL1 and NEUROD1 reveal heterogeneity in pulmonary neuroendocrine tumors and regulate distinct genetic programs
-
Borromeo, M. D. et al. ASCL1 and NEUROD1 reveal heterogeneity in pulmonary neuroendocrine tumors and regulate distinct genetic programs. Cell Rep. 16, 1259-1272 (2016).
-
(2016)
Cell Rep.
, vol.16
, pp. 1259-1272
-
-
Borromeo, M.D.1
-
25
-
-
0030936265
-
An achaete-scute homologue essential for neuroendocrine differentiation in the lung
-
Borges, M. et al. An achaete-scute homologue essential for neuroendocrine differentiation in the lung. Nature 386, 852-855 (1997).
-
(1997)
Nature
, vol.386
, pp. 852-855
-
-
Borges, M.1
-
26
-
-
84914172949
-
Transcriptional control of vertebrate neurogenesis by the proneural factor Ascl1
-
Vasconcelos, F. F. & Castro, D. S. Transcriptional control of vertebrate neurogenesis by the proneural factor Ascl1. Front. Cell. Neurosci. 8, 412 (2014).
-
(2014)
Front. Cell. Neurosci.
, vol.8
, pp. 412
-
-
Vasconcelos, F.F.1
Castro, D.S.2
-
27
-
-
84907938536
-
ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers
-
Augustyn, A. et al. ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers. Proc. Natl Acad. Sci. USA 111, 14788-14793 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 14788-14793
-
-
Augustyn, A.1
-
28
-
-
85019546383
-
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer
-
Lim, J. S. et al. Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Nature 545, 360-364 (2017).
-
(2017)
Nature
, vol.545
, pp. 360-364
-
-
Lim, J.S.1
-
29
-
-
0022006760
-
Establishment and identification of small cell lung cancer cell lines having classic and variant features
-
Carney, D. N. et al. Establishment and identification of small cell lung cancer cell lines having classic and variant features. Cancer Res. 45, 2913-2923 (1985).
-
(1985)
Cancer Res.
, vol.45
, pp. 2913-2923
-
-
Carney, D.N.1
-
30
-
-
85009505564
-
MYC drives progression of small cell lung cancer to a variant neuroendocrine subtype with vulnerability to Aurora kinase inhibition
-
Mollaoglu, G. et al. MYC drives progression of small cell lung cancer to a variant neuroendocrine subtype with vulnerability to Aurora kinase inhibition. Cancer Cell 31, 270-285 (2017).
-
(2017)
Cancer Cell
, vol.31
, pp. 270-285
-
-
Mollaoglu, G.1
-
31
-
-
77957969699
-
TTF1 expression in normal lung neuroendocrine cells and related tumors: Immunohistochemical study comparing two different monoclonal antibodies
-
La Rosa, S. et al. TTF1 expression in normal lung neuroendocrine cells and related tumors: immunohistochemical study comparing two different monoclonal antibodies. Virchows Arch. 457, 497-507 (2010).
-
(2010)
Virchows Arch.
, vol.457
, pp. 497-507
-
-
La Rosa, S.1
-
32
-
-
84878965845
-
NKX2-1/TTF-1: An enigmatic oncogene that functions as a double-edged sword for cancer cell survival and progression
-
Yamaguchi, T., Hosono, Y., Yanagisawa, K. & Takahashi, T. NKX2-1/TTF-1: an enigmatic oncogene that functions as a double-edged sword for cancer cell survival and progression. Cancer Cell 23, 718-723 (2013).
-
(2013)
Cancer Cell
, vol.23
, pp. 718-723
-
-
Yamaguchi, T.1
Hosono, Y.2
Yanagisawa, K.3
Takahashi, T.4
-
33
-
-
84951812171
-
Treatment of small-cell lung cancer: American Society of Clinical Oncology endorsement of the American College of Chest Physicians guideline
-
Rudin, C. M. et al. Treatment of small-cell lung cancer: American Society of Clinical Oncology endorsement of the American College of Chest Physicians guideline. J. Clin. Oncol. 33, 4106-4111 (2015).
-
(2015)
J. Clin. Oncol.
, vol.33
, pp. 4106-4111
-
-
Rudin, C.M.1
-
34
-
-
0021968689
-
Characterization of variant subclasses of cell lines derived from small cell lung cancer having distinctive biochemical, morphological, and growth properties
-
Gazdar, A. F., Carney, D. N., Nau, M. M. & Minna, J. D. Characterization of variant subclasses of cell lines derived from small cell lung cancer having distinctive biochemical, morphological, and growth properties. Cancer Res. 45, 2924-2930 (1985).
-
(1985)
Cancer Res.
, vol.45
, pp. 2924-2930
-
-
Gazdar, A.F.1
Carney, D.N.2
Nau, M.M.3
Minna, J.D.4
-
35
-
-
0025907433
-
Myc family DNA amplification in 107 tumors and tumor cell lines from patients with small cell lung cancer treated with different combination chemotherapy regimens
-
Brennan, J. et al. myc family DNA amplification in 107 tumors and tumor cell lines from patients with small cell lung cancer treated with different combination chemotherapy regimens. Cancer Res. 51, 1708-1712 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 1708-1712
-
-
Brennan, J.1
-
36
-
-
0020535311
-
In vitro radiation and chemotherapy sensitivity of established cell lines of human small cell lung cancer and its large cell morphological variants
-
Carney, D. N., Mitchell, J. B. & Kinsella, T. J. In vitro radiation and chemotherapy sensitivity of established cell lines of human small cell lung cancer and its large cell morphological variants. Cancer Res. 43, 2806-2811 (1983).
-
(1983)
Cancer Res.
, vol.43
, pp. 2806-2811
-
-
Carney, D.N.1
Mitchell, J.B.2
Kinsella, T.J.3
-
37
-
-
84880559818
-
Selective tropism of Seneca Valley virus for variant subtype small cell lung cancer
-
Poirier, J. T. et al. Selective tropism of Seneca Valley virus for variant subtype small cell lung cancer. J. Natl Cancer Inst. 105, 1059-1065 (2013).
-
(2013)
J. Natl Cancer Inst.
, vol.105
, pp. 1059-1065
-
-
Poirier, J.T.1
-
38
-
-
0029681702
-
MYC family DNA amplification in 126 tumor cell lines from patients with small cell lung cancer
-
Johnson, B. E. et al. MYC family DNA amplification in 126 tumor cell lines from patients with small cell lung cancer. J. Cell. Biochem. Suppl. 24, 210-217 (1996).
-
(1996)
J. Cell. Biochem. Suppl.
, vol.24
, pp. 210-217
-
-
Johnson, B.E.1
-
39
-
-
79751511326
-
A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer
-
Calbo, J. et al. A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer. Cancer Cell 19, 244-256 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 244-256
-
-
Calbo, J.1
-
40
-
-
84938209433
-
Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: Clinical update
-
Takebe, N. et al. Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update. Nat. Rev. Clin. Oncol. 12, 445-464 (2015).
-
(2015)
Nat. Rev. Clin. Oncol.
, vol.12
, pp. 445-464
-
-
Takebe, N.1
-
41
-
-
84960116298
-
Cancer stem cells in small cell lung cancer
-
Codony-Servat, J., Verlicchi, A. & Rosell, R. Cancer stem cells in small cell lung cancer. Transl Lung Cancer Res. 5, 16-25 (2016).
-
(2016)
Transl Lung Cancer Res.
, vol.5
, pp. 16-25
-
-
Codony-Servat, J.1
Verlicchi, A.2
Rosell, R.3
-
42
-
-
77349109478
-
Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy
-
Sullivan, J. P., Minna, J. D. & Shay, J. W. Evidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy. Cancer Metastasis Rev. 29, 61-72 (2010).
-
(2010)
Cancer Metastasis Rev.
, vol.29
, pp. 61-72
-
-
Sullivan, J.P.1
Minna, J.D.2
Shay, J.W.3
-
43
-
-
84938097346
-
Origins, genetic landscape, and emerging therapies of small cell lung cancer
-
Semenova, E. A., Nagel, R. & Berns, A. Origins, genetic landscape, and emerging therapies of small cell lung cancer. Genes Dev. 29, 1447-1462 (2015).
-
(2015)
Genes Dev.
, vol.29
, pp. 1447-1462
-
-
Semenova, E.A.1
Nagel, R.2
Berns, A.3
-
44
-
-
84949534082
-
Sox2, a key factor in the regulation of pluripotency and neural differentiation
-
Zhang, S. & Cui, W. Sox2, a key factor in the regulation of pluripotency and neural differentiation. World J. Stem Cells 6, 305-311 (2014).
-
(2014)
World J. Stem Cells
, vol.6
, pp. 305-311
-
-
Zhang, S.1
Cui, W.2
-
45
-
-
84866849548
-
Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
-
Rudin, C. M. et al. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nat. Genet. 44, 1111-1116 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 1111-1116
-
-
Rudin, C.M.1
-
46
-
-
84978437311
-
Identification and targeting of long-term tumor-propagating cells in small cell lung cancer
-
Jahchan, N. S. et al. Identification and targeting of long-term tumor-propagating cells in small cell lung cancer. Cell Rep. 16, 644-656 (2016).
-
(2016)
Cell Rep.
, vol.16
, pp. 644-656
-
-
Jahchan, N.S.1
-
47
-
-
54249112735
-
Small cell, big problem! Stem cells, root cause? Clin
-
Subramanian, J. & Govindan, R. Small cell, big problem! Stem cells, root cause? Clin. Lung Cancer 9, 252-253 (2008).
-
(2008)
Lung Cancer
, vol.9
, pp. 252-253
-
-
Subramanian, J.1
Govindan, R.2
-
48
-
-
67449145304
-
-
IARC Press
-
Travis, W. D., Brambilla, E., Burke, A. P., Marx, A., & Nicholson, A. G. WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart (IARC Press, 2015).
-
(2015)
WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart
-
-
Travis, W.D.1
Brambilla, E.2
Burke, A.P.3
Marx, A.4
Nicholson, A.G.5
-
49
-
-
84882995953
-
Cancer stem cells and tumor transdifferentiation: Implications for novel therapeutic strategies
-
Shekhani, M. T., Jayanthy, A. S., Maddodi, N. & Setaluri, V. Cancer stem cells and tumor transdifferentiation: implications for novel therapeutic strategies. Am. J. Stem Cells 2, 52-61 (2013).
-
(2013)
Am. J. Stem Cells
, vol.2
, pp. 52-61
-
-
Shekhani, M.T.1
Jayanthy, A.S.2
Maddodi, N.3
Setaluri, V.4
-
50
-
-
79953118839
-
Genotypic and histolgical evolution of lung cancers acquiring resistance to EGFR inhibitors
-
Sequist, L. et al. Genotypic and histolgical evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci. Transl Med. 3, 75ra26 (2011).
-
(2011)
Sci. Transl Med.
, vol.3
, pp. 75ra26
-
-
Sequist, L.1
-
51
-
-
84924590266
-
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer
-
Niederst, M. J. et al. RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer. Nature Commun. 6, 6377 (2015).
-
(2015)
Nature Commun.
, vol.6
, pp. 6377
-
-
Niederst, M.J.1
-
52
-
-
84929949436
-
The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung
-
Gazdar, A. F. et al. The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung. J. Thorac Oncol. 10, 553-564 (2015).
-
(2015)
J. Thorac Oncol.
, vol.10
, pp. 553-564
-
-
Gazdar, A.F.1
-
53
-
-
0033927099
-
Molecular changes in the bronchial epithelium of patients with small cell lung cancer
-
Wistuba, I. I. et al. Molecular changes in the bronchial epithelium of patients with small cell lung cancer. Clin. Cancer Res. 6, 2604-2610 (2000).
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2604-2610
-
-
Wistuba, I.I.1
-
54
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Alexandrov, L. B. et al. Signatures of mutational processes in human cancer. Nature 500, 415-421 (2013).
-
(2013)
Nature
, vol.500
, pp. 415-421
-
-
Alexandrov, L.B.1
-
55
-
-
74449085934
-
A small-cell lung cancer genome with complex signatures of tobacco exposure
-
Pleasance, E. D. et al. A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature 463, 184-190 (2010).
-
(2010)
Nature
, vol.463
, pp. 184-190
-
-
Pleasance, E.D.1
-
56
-
-
84866434919
-
Genomic landscape of non-small cell lung cancer in smokers and never-smokers
-
Govindan, R. et al. Genomic landscape of non-small cell lung cancer in smokers and never-smokers. Cell 150, 1121-1134 (2012).
-
(2012)
Cell
, vol.150
, pp. 1121-1134
-
-
Govindan, R.1
-
57
-
-
84883432724
-
An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers
-
Roberts, S. A. et al. An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers. Nat. Genet. 45, 970-976 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 970-976
-
-
Roberts, S.A.1
-
58
-
-
0141523025
-
Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model
-
Meuwissen, R. et al. Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model. Cancer Cell 4, 181-189 (2003).
-
(2003)
Cancer Cell
, vol.4
, pp. 181-189
-
-
Meuwissen, R.1
-
59
-
-
84896333670
-
Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing
-
McFadden, D. G. et al. Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing. Cell 156, 1298-1311 (2014).
-
(2014)
Cell
, vol.156
, pp. 1298-1311
-
-
McFadden, D.G.1
-
60
-
-
84875813017
-
Mouse models for lung cancer
-
Kwon, M. C. & Berns, A. Mouse models for lung cancer. Mol. Oncol. 7, 165-177 (2013).
-
(2013)
Mol. Oncol.
, vol.7
, pp. 165-177
-
-
Kwon, M.C.1
Berns, A.2
-
61
-
-
0020038032
-
Specific chromosome defect associated with human small-cell lung cancer; Deletion 3p(14-23)
-
Whang-Peng, J. et al. Specific chromosome defect associated with human small-cell lung cancer; deletion 3p(14-23). Science 215, 181-182 (1982).
-
(1982)
Science
, vol.215
, pp. 181-182
-
-
Whang-Peng, J.1
-
62
-
-
19244370711
-
High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints
-
Wistuba, I. I. et al. High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res. 60, 1949-1960 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 1949-1960
-
-
Wistuba, I.I.1
-
63
-
-
33751100403
-
Functional analysis of lung tumor suppressor activity at 3p21.3
-
ter Elst, A. et al. Functional analysis of lung tumor suppressor activity at 3p21.3. Genes Chromosomes Cancer 45, 1077-1093 (2006).
-
(2006)
Genes Chromosomes Cancer
, vol.45
, pp. 1077-1093
-
-
Ter Elst, A.1
-
64
-
-
0037037787
-
Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers
-
Zabarovsky, E. R., Lerman, M. I. & Minna, J. D. Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers. Oncogene 21, 6915-6935 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 6915-6935
-
-
Zabarovsky, E.R.1
Lerman, M.I.2
Minna, J.D.3
-
65
-
-
0031900879
-
Fhit in human cancer
-
Sozzi, G., Huebner, K. & Croce, C. M. Fhit in human cancer. Adv. Cancer Res. 74, 141-166 (1998).
-
(1998)
Adv. Cancer Res.
, vol.74
, pp. 141-166
-
-
Sozzi, G.1
Huebner, K.2
Croce, C.M.3
-
66
-
-
77449123163
-
Chromosomal and genomic changes in lung cancer
-
Varella-Garcia, M. Chromosomal and genomic changes in lung cancer. Cell Adh. Migr. 4, 100-106 (2010).
-
(2010)
Cell Adh. Migr.
, vol.4
, pp. 100-106
-
-
Varella-Garcia, M.1
-
67
-
-
0034327412
-
The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: Identification and evaluation of the resident candidate tumor suppressor genes
-
Lerman, M. I. & Minna, J. D. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. Cancer Res. 60, 6116-6133 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 6116-6133
-
-
Lerman, M.I.1
Minna, J.D.2
-
69
-
-
0028234984
-
Molecular analysis of the von Hippel-Lindau disease tumor suppressor gene in human lung cancer cell lines
-
Sekido, Y. et al. Molecular analysis of the von Hippel-Lindau disease tumor suppressor gene in human lung cancer cell lines. Oncogene 9, 1599-1604 (1994).
-
(1994)
Oncogene
, vol.9
, pp. 1599-1604
-
-
Sekido, Y.1
-
70
-
-
84954403082
-
NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas
-
Meder, L. et al. NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas. Int. J. Cancer 138, 927-938 (2016).
-
(2016)
Int. J. Cancer
, vol.138
, pp. 927-938
-
-
Meder, L.1
-
71
-
-
84940403711
-
A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo
-
Saunders, L. R. et al. A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo. Sci. Transl Med. 7, 302ra136 (2015).
-
(2015)
Sci. Transl Med.
, vol.7
, pp. 302ra136
-
-
Saunders, L.R.1
-
72
-
-
84896082963
-
From fly wings to targeted cancer therapies: A centennial for notch signaling
-
Ntziachristos, P., Lim, J. S., Sage, J. & Aifantis, I. From fly wings to targeted cancer therapies: a centennial for notch signaling. Cancer Cell 25, 318-334 (2014).
-
(2014)
Cancer Cell
, vol.25
, pp. 318-334
-
-
Ntziachristos, P.1
Lim, J.S.2
Sage, J.3
Aifantis, I.4
-
73
-
-
85021448605
-
Toppling high-grade pulmonary neuroendocrine tumors with a DLL3-targeted trojan horse
-
Dylla, S. J. Toppling high-grade pulmonary neuroendocrine tumors with a DLL3-targeted trojan horse. Mol. Cell. Oncol. 3, e1101515 (2016).
-
(2016)
Mol. Cell. Oncol.
, vol.3
, pp. e1101515
-
-
Dylla, S.J.1
-
74
-
-
0021053735
-
Amplification and expression of the c-myc oncogene in human lung cancer cell lines
-
Little, C. D., Nau, M. M., Carney, D. N., Gazdar, A. F. & Minna, J. D. Amplification and expression of the c-myc oncogene in human lung cancer cell lines. Nature 306, 194-196 (1983).
-
(1983)
Nature
, vol.306
, pp. 194-196
-
-
Little, C.D.1
Nau, M.M.2
Carney, D.N.3
Gazdar, A.F.4
Minna, J.D.5
-
75
-
-
0022392771
-
L-Myc, a new myc-related gene amplified and expressed in human small cell lung cancer
-
Nau, M. M. et al. L-Myc, a new myc-related gene amplified and expressed in human small cell lung cancer. Nature 318, 69-73 (1985).
-
(1985)
Nature
, vol.318
, pp. 69-73
-
-
Nau, M.M.1
-
76
-
-
0026494173
-
Myc family DNA amplification in tumors and tumor cell lines from patients with small-cell lung cancer
-
Johnson, B. E., Brennan, J. F., Ihde, D. C. & Gazdar, A. F. myc family DNA amplification in tumors and tumor cell lines from patients with small-cell lung cancer. J. Natl Cancer Inst. Monogr. (13), 39-43 (1992).
-
(1992)
J. Natl Cancer Inst. Monogr.
, Issue.13
, pp. 39-43
-
-
Johnson, B.E.1
Brennan, J.F.2
Ihde, D.C.3
Gazdar, A.F.4
-
77
-
-
84925229549
-
MYC amplification is associated with poor survival in small cell lung cancer: A chromogenic in situ hybridization study
-
Alves Rde, C., Meurer, R. T. & Roehe, A. V. MYC amplification is associated with poor survival in small cell lung cancer: a chromogenic in situ hybridization study. J. Cancer Res. Clin. Oncol. 140, 2021-2025 (2014).
-
(2014)
J. Cancer Res. Clin. Oncol.
, vol.140
, pp. 2021-2025
-
-
Alves Rde, C.1
Meurer, R.T.2
Roehe, A.V.3
-
78
-
-
84974605091
-
Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer
-
Kim, D. W. et al. Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer. Genes Dev. 30, 1289-1299 (2016).
-
(2016)
Genes Dev.
, vol.30
, pp. 1289-1299
-
-
Kim, D.W.1
-
79
-
-
84971508916
-
Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation
-
Fiorentino, F. P. et al. Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation. Oncotarget 7, 31014-31028 (2016).
-
(2016)
Oncotarget
, vol.7
, pp. 31014-31028
-
-
Fiorentino, F.P.1
-
80
-
-
84867627577
-
A framework for identification of actionable cancer genome dependencies in small cell lung cancer
-
Sos, M. L. et al. A framework for identification of actionable cancer genome dependencies in small cell lung cancer. Proc. Natl Acad. Sci. USA 109, 17034-17039 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 17034-17039
-
-
Sos, M.L.1
-
81
-
-
84990988111
-
Barasertib (AZD1152), a small molecule Aurora B Inhibitor, inhibits the growth of SCLC cell lines in vitro and in vivo
-
Helfrich, B. A. et al. Barasertib (AZD1152), a small molecule Aurora B Inhibitor, inhibits the growth of SCLC cell lines in vitro and in vivo. Mol. Cancer Ther. 15, 2314-2322 (2016).
-
(2016)
Mol. Cancer Ther.
, vol.15
, pp. 2314-2322
-
-
Helfrich, B.A.1
-
82
-
-
84895821044
-
MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1
-
Romero, O. A. et al. MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1. Cancer Discov. 4, 292-303 (2014).
-
(2014)
Cancer Discov.
, vol.4
, pp. 292-303
-
-
Romero, O.A.1
-
83
-
-
69849115509
-
Oncogenic mutation of PIK3CA in small cell lung carcinoma: A potential therapeutic target pathway for chemotherapy-resistant lung cancer
-
Shibata, T., Kokubu, A., Tsuta, K. & Hirohashi, S. Oncogenic mutation of PIK3CA in small cell lung carcinoma: a potential therapeutic target pathway for chemotherapy-resistant lung cancer. Cancer Lett. 283, 203-211 (2009).
-
(2009)
Cancer Lett.
, vol.283
, pp. 203-211
-
-
Shibata, T.1
Kokubu, A.2
Tsuta, K.3
Hirohashi, S.4
-
84
-
-
84900437332
-
PTEN is a potent suppressor of small cell lung cancer
-
Cui, M. et al. PTEN is a potent suppressor of small cell lung cancer. Mol. Cancer Res. 12, 654-659 (2014).
-
(2014)
Mol. Cancer Res.
, vol.12
, pp. 654-659
-
-
Cui, M.1
-
85
-
-
84902669919
-
FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies
-
Wynes, M. W. et al. FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies. Clin. Cancer Res. 20, 3299-3309 (2014).
-
(2014)
Clin. Cancer Res.
, vol.20
, pp. 3299-3309
-
-
Wynes, M.W.1
-
86
-
-
84893717646
-
Fibroblast growth factor receptor 1 (FGFR1) amplification is a potential therapeutic target in small-cell lung cancer
-
Schultheis, A. M. et al. Fibroblast growth factor receptor 1 (FGFR1) amplification is a potential therapeutic target in small-cell lung cancer. Mod. Pathol. 27, 214-221 (2014).
-
(2014)
Mod. Pathol.
, vol.27
, pp. 214-221
-
-
Schultheis, A.M.1
-
87
-
-
84982135138
-
Is the canonical RAF/MEK/ERK signaling pathway a therapeutic target in SCLC?
-
Cristea, S. & Sage, J. Is the canonical RAF/MEK/ERK signaling pathway a therapeutic target in SCLC? J. Thorac Oncol. 11, 1233-1241 (2016).
-
(2016)
J. Thorac Oncol.
, vol.11
, pp. 1233-1241
-
-
Cristea, S.1
Sage, J.2
-
88
-
-
84987781487
-
Targeting the cancer epigenome for therapy
-
Jones, P. A., Issa, J. P. & Baylin, S. Targeting the cancer epigenome for therapy. Nat. Rev. Genet. 17, 630-641 (2016).
-
(2016)
Nat. Rev. Genet.
, vol.17
, pp. 630-641
-
-
Jones, P.A.1
Issa, J.P.2
Baylin, S.3
-
89
-
-
84963959599
-
Epigenetic silencing of tumor suppressor genes: Paradigms, puzzles, and potential
-
Kazanets, A., Shorstova, T., Hilmi, K., Marques, M. & Witcher, M. Epigenetic silencing of tumor suppressor genes: paradigms, puzzles, and potential. Biochim. Biophys. Acta 1865, 275-288 (2016).
-
(2016)
Biochim. Biophys. Acta
, vol.1865
, pp. 275-288
-
-
Kazanets, A.1
Shorstova, T.2
Hilmi, K.3
Marques, M.4
Witcher, M.5
-
90
-
-
84880921962
-
The DNA methylation landscape of small cell lung cancer suggests a differentiation defect of neuroendocrine cells
-
Kalari, S., Jung, M., Kernstine, K. H., Takahashi, T. & Pfeifer, G. P. The DNA methylation landscape of small cell lung cancer suggests a differentiation defect of neuroendocrine cells. Oncogene 32, 3559-3568 (2013).
-
(2013)
Oncogene
, vol.32
, pp. 3559-3568
-
-
Kalari, S.1
Jung, M.2
Kernstine, K.H.3
Takahashi, T.4
Pfeifer, G.P.5
-
91
-
-
84948570001
-
DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2
-
Poirier, J. T. et al. DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2. Oncogene 34, 5869-5878 (2015).
-
(2015)
Oncogene
, vol.34
, pp. 5869-5878
-
-
Poirier, J.T.1
-
92
-
-
84981322711
-
EZH2 promotes progression of small cell lung cancer by suppressing the TGF-ß-Smad-ASCL1 pathway
-
Murai, F. et al. EZH2 promotes progression of small cell lung cancer by suppressing the TGF-ß-Smad-ASCL1 pathway. Cell Discov. 1, 15026 (2015).
-
(2015)
Cell Discov.
, vol.1
, pp. 15026
-
-
Murai, F.1
-
93
-
-
0035932393
-
Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours
-
Agathanggelou, A. et al. Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours. Oncogene 20, 1509-1518. (2001).
-
(2001)
Oncogene
, vol.20
, pp. 1509-1518
-
-
Agathanggelou, A.1
-
94
-
-
0035795676
-
Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression
-
Burbee, D. G. et al. Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression. J. Natl Cancer Inst. 93, 691-699 (2001).
-
(2001)
J. Natl Cancer Inst.
, vol.93
, pp. 691-699
-
-
Burbee, D.G.1
-
95
-
-
55949136562
-
Roles of the EZH2 histone methyltransferase in cancer epigenetics
-
Simon, J. A. & Lange, C. A. Roles of the EZH2 histone methyltransferase in cancer epigenetics. Mutat. Res. 647, 21-29 (2008).
-
(2008)
Mutat. Res.
, vol.647
, pp. 21-29
-
-
Simon, J.A.1
Lange, C.A.2
-
96
-
-
84957998842
-
Prognostic value of high EZH2 expression in patients with different types of cancer: A systematic review with meta-analysis
-
Jiang, T. et al. Prognostic value of high EZH2 expression in patients with different types of cancer: a systematic review with meta-analysis. Oncotarget 7, 4584-4597 (2016).
-
(2016)
Oncotarget
, vol.7
, pp. 4584-4597
-
-
Jiang, T.1
-
97
-
-
84957555628
-
Targeting EZH2 in cancer
-
Kim, K. H. & Roberts, C. W. Targeting EZH2 in cancer. Nat. Med. 22, 128-134 (2016).
-
(2016)
Nat. Med.
, vol.22
, pp. 128-134
-
-
Kim, K.H.1
Roberts, C.W.2
-
98
-
-
84866851740
-
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
-
Peifer, M. et al. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat. Genet. 44, 1104-1110 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 1104-1110
-
-
Peifer, M.1
-
99
-
-
85015959352
-
Small cell lung cancer exhibits frequent inactivating mutations in the histone methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance)
-
Augert, A. et al. Small cell lung cancer exhibits frequent inactivating mutations in the histone methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance). J. Thorac Oncol. 12, 704-713 (2017).
-
(2017)
J. Thorac Oncol.
, vol.12
, pp. 704-713
-
-
Augert, A.1
-
100
-
-
84962019891
-
Bromodomain and hedgehog pathway targets in small cell lung cancer
-
Kaur, G. et al. Bromodomain and hedgehog pathway targets in small cell lung cancer. Cancer Lett. 3 71, 225-239 (2016).
-
(2016)
Cancer Lett.
, vol.371
, pp. 225-239
-
-
Kaur, G.1
-
101
-
-
84866324536
-
Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1
-
Byers, L. A. et al. Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1. Cancer Discov. 2, 798-811 (2012).
-
(2012)
Cancer Discov.
, vol.2
, pp. 798-811
-
-
Byers, L.A.1
-
102
-
-
85012931265
-
Chemosensitive relapse in small cell lung cancer proceeds through an EZH2-SLFN11 axis
-
Gardner, E. E. et al. Chemosensitive relapse in small cell lung cancer proceeds through an EZH2-SLFN11 axis. Cancer Cell 31, 286-299 (2017).
-
(2017)
Cancer Cell
, vol.31
, pp. 286-299
-
-
Gardner, E.E.1
-
103
-
-
84880893647
-
EZH2 promotes E2F-driven SCLC tumorigenesis through modulation of apoptosis and cell-cycle regulation
-
Hubaux, R. et al. EZH2 promotes E2F-driven SCLC tumorigenesis through modulation of apoptosis and cell-cycle regulation. J. Thorac Oncol. 8, 1102-1106 (2013).
-
(2013)
J. Thorac Oncol.
, vol.8
, pp. 1102-1106
-
-
Hubaux, R.1
-
104
-
-
85020202044
-
Role of EZH2 in cancer stem cells: From biological insight to a therapeutic target
-
Wen, Y., Cai, J., Hou, Y., Huang, Z. & Wang, Z. Role of EZH2 in cancer stem cells: from biological insight to a therapeutic target. Oncotarget 8, 37974-37990 (2017).
-
(2017)
Oncotarget
, vol.8
, pp. 37974-37990
-
-
Wen, Y.1
Cai, J.2
Hou, Y.3
Huang, Z.4
Wang, Z.5
-
105
-
-
85012024585
-
Developing EZH2-targeted therapy for lung cancer
-
Frankel, A. E., Liu, X. & Minna, J. D. Developing EZH2-targeted therapy for lung cancer. Cancer Discov. 6, 949-952 (2016).
-
(2016)
Cancer Discov.
, vol.6
, pp. 949-952
-
-
Frankel, A.E.1
Liu, X.2
Minna, J.D.3
-
106
-
-
85008679957
-
Antitumor activity of LSD1 inhibitors in lung cancer
-
Mohammad, H. P. & Kruger, R. G. Antitumor activity of LSD1 inhibitors in lung cancer. Mol. Cell. Oncol. 3, e1117700 (2016).
-
(2016)
Mol. Cell. Oncol.
, vol.3
, pp. e1117700
-
-
Mohammad, H.P.1
Kruger, R.G.2
-
107
-
-
84937429405
-
A DNA hypomethylation signature predicts antitumor activity of LSD1 inhibitors in SCLC
-
Mohammad, H. P. et al. A DNA hypomethylation signature predicts antitumor activity of LSD1 inhibitors in SCLC. Cancer Cell 28, 57-69 (2015).
-
(2015)
Cancer Cell
, vol.28
, pp. 57-69
-
-
Mohammad, H.P.1
-
108
-
-
84919495606
-
Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor
-
Christensen, C. L. et al. Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor. Cancer Cell 26, 909-922 (2014).
-
(2014)
Cancer Cell
, vol.26
, pp. 909-922
-
-
Christensen, C.L.1
-
109
-
-
84988355089
-
NFIB overexpression cooperates with Rb/p53 deletion to promote small cell lung cancer
-
Wu, N. et al. NFIB overexpression cooperates with Rb/p53 deletion to promote small cell lung cancer. Oncotarget 7, 57514-57524 (2016).
-
(2016)
Oncotarget
, vol.7
, pp. 57514-57524
-
-
Wu, N.1
-
110
-
-
84978388629
-
Transcription factor NFIB is a driver of small cell lung cancer progression in mice and marks metastatic disease in patients
-
Semenova, E. A. et al. Transcription factor NFIB is a driver of small cell lung cancer progression in mice and marks metastatic disease in patients. Cell Rep. 16, 631-643 (2016).
-
(2016)
Cell Rep.
, vol.16
, pp. 631-643
-
-
Semenova, E.A.1
-
111
-
-
84978379634
-
Nfib promotes metastasis through a widespread increase in chromatin accessibility
-
Denny, S. K. et al. Nfib promotes metastasis through a widespread increase in chromatin accessibility. Cell 166, 328-342 (2016).
-
(2016)
Cell
, vol.166
, pp. 328-342
-
-
Denny, S.K.1
-
112
-
-
84982162351
-
Opening a chromatin gate to metastasis
-
Minna, J. D. & Johnson, J. E. Opening a chromatin gate to metastasis. Cell 166, 275-276 (2016).
-
(2016)
Cell
, vol.166
, pp. 275-276
-
-
Minna, J.D.1
Johnson, J.E.2
-
113
-
-
84994238857
-
Small cell lung cancer cell line screen of oncology drugs and investigational agents identifies patterns with gene and microRNA expression
-
Polley, E. et al. Small cell lung cancer cell line screen of oncology drugs and investigational agents identifies patterns with gene and microRNA expression. J. Natl Cancer Inst. 108, djw122 (2016).
-
(2016)
J. Natl Cancer Inst.
, vol.108
, pp. djw122
-
-
Polley, E.1
-
114
-
-
84996844180
-
Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemosensitive and chemorefractory small-cell lung cancer
-
Carter, L. et al. Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemosensitive and chemorefractory small-cell lung cancer. Nat. Med. 23, 114-119 (2017).
-
(2017)
Nat. Med.
, vol.23
, pp. 114-119
-
-
Carter, L.1
-
115
-
-
84876146708
-
The schlafen family of proteins and their regulation by interferons
-
Mavrommatis, E., Fish, E. N. & Platanias, L. C. The schlafen family of proteins and their regulation by interferons. J. Interferon Cytokine Res. 33, 206-210 (2013).
-
(2013)
J. Interferon Cytokine Res.
, vol.33
, pp. 206-210
-
-
Mavrommatis, E.1
Fish, E.N.2
Platanias, L.C.3
-
116
-
-
84998827879
-
Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition
-
Murai, J. et al. Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition. Oncotarget 7, 76534-76550 (2016).
-
(2016)
Oncotarget
, vol.7
, pp. 76534-76550
-
-
Murai, J.1
-
117
-
-
85012890398
-
Awakening of "schlafen11" to tackle chemotherapy resistance in SCLC
-
Berns, K. & Berns, A. Awakening of "Schlafen11" to tackle chemotherapy resistance in SCLC. Cancer Cell 31, 169-171 (2017).
-
(2017)
Cancer Cell
, vol.31
, pp. 169-171
-
-
Berns, K.1
Berns, A.2
-
118
-
-
85020775070
-
Methylation of SLFN11 is a marker of poor prognosis and cisplatin resistance in colorectal cancer
-
He, T. et al. Methylation of SLFN11 is a marker of poor prognosis and cisplatin resistance in colorectal cancer. Epigenomics 9, 849-862 (2017).
-
(2017)
Epigenomics
, vol.9
, pp. 849-862
-
-
He, T.1
-
119
-
-
85028352113
-
MCAM mediates chemoresistance in small cell lung cancer via the PI3K/AKT/SOX2 signaling pathway
-
Tripathi, S. C. et al. MCAM mediates chemoresistance in small cell lung cancer via the PI3K/AKT/SOX2 signaling pathway. Cancer Res. 77, 4414-4425 (2017).
-
(2017)
Cancer Res.
, vol.77
, pp. 4414-4425
-
-
Tripathi, S.C.1
-
120
-
-
85023745986
-
CHK1 inhibition in small cell lung cancer produces single-agent activity in biomarker-defined disease subsets and combination activity with cisplatin or olaparib
-
Sen, T. et al. CHK1 inhibition in small cell lung cancer produces single-agent activity in biomarker-defined disease subsets and combination activity with cisplatin or olaparib. Cancer Res. 77, 3870-3884 (2017).
-
(2017)
Cancer Res.
, vol.77
, pp. 3870-3884
-
-
Sen, T.1
-
121
-
-
84963610096
-
Activation of the PI3K/mTOR pathway following PARP inhibition in small cell lung cancer
-
Cardnell, R. J. et al. Activation of the PI3K/mTOR pathway following PARP inhibition in small cell lung cancer. PLoS ONE 11, e0152584 (2016).
-
(2016)
PLoS ONE
, vol.11
, pp. e0152584
-
-
Cardnell, R.J.1
-
122
-
-
84941986957
-
Small cell lung cancer: Will recent progress lead to improved outcomes? Clin
-
Pietanza, M. C., Byers, L. A., Minna, J. D. & Rudin, C. M. Small cell lung cancer: will recent progress lead to improved outcomes? Clin. Cancer Res. 21, 2244-2255 (2015).
-
(2015)
Cancer Res.
, vol.21
, pp. 2244-2255
-
-
Pietanza, M.C.1
Byers, L.A.2
Minna, J.D.3
Rudin, C.M.4
-
123
-
-
85018417226
-
Dynamic variations in epithelial-to-mesenchymal transition (EMT), ATM, and SLFN11 govern response to PARP inhibitors and cisplatin in small cell lung cancer
-
Stewart, C. A. et al. Dynamic variations in epithelial-to-mesenchymal transition (EMT), ATM, and SLFN11 govern response to PARP inhibitors and cisplatin in small cell lung cancer. Oncotarget 8, 28575-28587 (2017).
-
(2017)
Oncotarget
, vol.8
, pp. 28575-28587
-
-
Stewart, C.A.1
-
124
-
-
85007579435
-
Cancer therapy due to apoptosis: Galectin-9
-
Fujita, K. et al. Cancer therapy due to apoptosis: galectin-9. Int. J. Mol. Sci. 18, 74 (2017).
-
(2017)
Int. J. Mol. Sci.
, vol.18
, pp. 74
-
-
Fujita, K.1
-
125
-
-
0024452546
-
P53: A frequent target for genetic abnormalities in lung cancer
-
Takahashi, T. et al. p53: a frequent target for genetic abnormalities in lung cancer. Science 246, 491-494 (1989).
-
(1989)
Science
, vol.246
, pp. 491-494
-
-
Takahashi, T.1
-
126
-
-
69249132204
-
Pathogenesis of lung cancer signalling pathways: Roadmap for therapies
-
Brambilla, E. & Gazdar, A. Pathogenesis of lung cancer signalling pathways: roadmap for therapies. Eur. Respir. J. 33, 1485-1497 (2009).
-
(2009)
Eur. Respir. J.
, vol.33
, pp. 1485-1497
-
-
Brambilla, E.1
Gazdar, A.2
-
127
-
-
84944166647
-
Targeting BCL2-proteins for the treatment of solid tumours
-
Vogler, M. Targeting BCL2-proteins for the treatment of solid tumours. Adv. Med. 2014, 943648 (2014).
-
(2014)
Adv. Med.
, vol.2014
, pp. 943648
-
-
Vogler, M.1
-
128
-
-
84866343458
-
A genetic snapshot of small cell lung cancer
-
Rosell, R. & Wannesson, L. A genetic snapshot of small cell lung cancer. Cancer Discov. 2, 769-771 (2012).
-
(2012)
Cancer Discov.
, vol.2
, pp. 769-771
-
-
Rosell, R.1
Wannesson, L.2
-
129
-
-
84928761118
-
Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
-
Rizvi, N. A. et al. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science 348, 124-128 (2015).
-
(2015)
Science
, vol.348
, pp. 124-128
-
-
Rizvi, N.A.1
-
130
-
-
84981554895
-
The future of immunotherapy in the treatment of small cell lung cancer
-
Horn, L., Reck, M. & Spigel, D. R. The future of immunotherapy in the treatment of small cell lung cancer. Oncologist 21, 910-921 (2016).
-
(2016)
Oncologist
, vol.21
, pp. 910-921
-
-
Horn, L.1
Reck, M.2
Spigel, D.R.3
-
131
-
-
84962254409
-
Immunotherapy for small-cell lung cancer: Emerging evidence
-
Reck, M., Heigener, D. & Reinmuth, N. Immunotherapy for small-cell lung cancer: emerging evidence. Future Oncol. 12, 931-943 (2016).
-
(2016)
Future Oncol.
, vol.12
, pp. 931-943
-
-
Reck, M.1
Heigener, D.2
Reinmuth, N.3
-
132
-
-
84938416174
-
Vaccine immunotherapy in lung cancer: Clinical experience and future directions
-
Freeman-Keller, M., Goldman, J. & Gray, J. Vaccine immunotherapy in lung cancer: clinical experience and future directions. Pharmacol. Ther. 153, 1-9 (2015).
-
(2015)
Pharmacol. Ther.
, vol.153
, pp. 1-9
-
-
Freeman-Keller, M.1
Goldman, J.2
Gray, J.3
-
133
-
-
84928659261
-
Intratumoral anti-HuD immunotoxin therapy for small cell lung cancer and neuroblastoma
-
Ehrlich, D., Wang, B., Lu, W., Dowling, P. & Yuan, R. Intratumoral anti-HuD immunotoxin therapy for small cell lung cancer and neuroblastoma. J. Hematol. Oncol. 7, 91 (2014).
-
(2014)
J. Hematol. Oncol.
, vol.7
, pp. 91
-
-
Ehrlich, D.1
Wang, B.2
Lu, W.3
Dowling, P.4
Yuan, R.5
-
134
-
-
84978381315
-
CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer
-
Weiskopf, K. et al. CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. J. Clin. Invest. 126, 2610-2620 (2016).
-
(2016)
J. Clin. Invest.
, vol.126
, pp. 2610-2620
-
-
Weiskopf, K.1
-
135
-
-
84908343167
-
Liquid biopsies in lung cancer: The new ambrosia of researchers
-
Rolfo, C. et al. Liquid biopsies in lung cancer: the new ambrosia of researchers. Biochim. Biophys. Acta 1846, 539-546 (2014).
-
(2014)
Biochim. Biophys. Acta
, vol.1846
, pp. 539-546
-
-
Rolfo, C.1
-
136
-
-
85028324346
-
The clinical utility for circulating tumour cells in patients with small cell lung cancer
-
Foy, V., Fernandez-Gutierrez, F., Faivre-Finn, C., Dive, C. & Blackhall, F. The clinical utility for circulating tumour cells in patients with small cell lung cancer. Transl Lung Cancer Res. 6, 409-417 (2017).
-
(2017)
Transl Lung Cancer Res.
, vol.6
, pp. 409-417
-
-
Foy, V.1
Fernandez-Gutierrez, F.2
Faivre-Finn, C.3
Dive, C.4
Blackhall, F.5
-
137
-
-
84873866902
-
Spheroid culture of primary lung cancer cells with neuregulin 1/HER3 pathway activation
-
Endo, H. et al. Spheroid culture of primary lung cancer cells with neuregulin 1/HER3 pathway activation. J. Thorac Oncol. 8, 131-139 (2013).
-
(2013)
J. Thorac Oncol.
, vol.8
, pp. 131-139
-
-
Endo, H.1
-
138
-
-
84884281697
-
Lung cancer-initiating cells: A novel target for cancer therapy
-
Morrison, B. J., Morris, J. C. & Steel, J. C. Lung cancer-initiating cells: a novel target for cancer therapy. Target Oncol. 8, 159-172 (2013).
-
(2013)
Target Oncol.
, vol.8
, pp. 159-172
-
-
Morrison, B.J.1
Morris, J.C.2
Steel, J.C.3
-
139
-
-
84936940261
-
Paraneoplastic syndromes: The way to an early diagnosis of lung cancer
-
Paraschiv, B., Diaconu, C. C., Toma, C. L. & Bogdan, M. A. Paraneoplastic syndromes: the way to an early diagnosis of lung cancer. Pneumologia 64, 14-19 (2015).
-
(2015)
Pneumologia
, vol.64
, pp. 14-19
-
-
Paraschiv, B.1
Diaconu, C.C.2
Toma, C.L.3
Bogdan, M.A.4
-
140
-
-
84916204173
-
Paraneoplastic syndromes associated with lung cancer
-
Kanaji, N. et al. Paraneoplastic syndromes associated with lung cancer. World J. Clin. Oncol. 5, 197-223 (2014).
-
(2014)
World J. Clin. Oncol.
, vol.5
, pp. 197-223
-
-
Kanaji, N.1
-
141
-
-
49749189195
-
A case of pluriglandular syndrome: "diabetes of bearded women"
-
Brown, W. A case of pluriglandular syndrome: "Diabetes of bearded women". Lancet 212, 1022-1023 (1928).
-
(1928)
Lancet
, vol.212
, pp. 1022-1023
-
-
Brown, W.1
-
142
-
-
0021807624
-
Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer
-
Cuttitta, F. et al. Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer. Nature 316, 823-826 (1985).
-
(1985)
Nature
, vol.316
, pp. 823-826
-
-
Cuttitta, F.1
-
143
-
-
84962822743
-
Somatostatin receptors in lung cancer: From function to molecular imaging and therapeutics
-
Callison, J. C. Jr, Walker, R. C. & Massion, P. P. Somatostatin receptors in lung cancer: from function to molecular imaging and therapeutics. J. Lung Cancer 10, 69-76 (2011).
-
(2011)
J. Lung Cancer
, vol.10
, pp. 69-76
-
-
Callison, J.C.1
Walker, R.C.2
Massion, P.P.3
-
144
-
-
81255211667
-
Lambert-Eaton myasthenic syndrome: From clinical characteristics to therapeutic strategies
-
Titulaer, M. J., Lang, B. & Verschuuren, J. J. Lambert-Eaton myasthenic syndrome: from clinical characteristics to therapeutic strategies. Lancet Neurol. 10, 1098-1107 (2011).
-
(2011)
Lancet Neurol.
, vol.10
, pp. 1098-1107
-
-
Titulaer, M.J.1
Lang, B.2
Verschuuren, J.J.3
-
145
-
-
84861742450
-
Molecular and cellular biology of neuroendocrine lung tumors: Evidence for separate biological entities
-
Swarts, D. R., Ramaekers, F. C. & Speel, E. J. Molecular and cellular biology of neuroendocrine lung tumors: evidence for separate biological entities. Biochim. Biophys. Acta 1826, 255-271 (2012).
-
(2012)
Biochim. Biophys. Acta
, vol.1826
, pp. 255-271
-
-
Swarts, D.R.1
Ramaekers, F.C.2
Speel, E.J.3
-
146
-
-
84978505017
-
Next-generation sequencing of pulmonary large cell neuroendocrine carcinoma reveals small cell carcinoma-like and non-small cell carcinoma-like subsets
-
Rekhtman, N. et al. Next-generation sequencing of pulmonary large cell neuroendocrine carcinoma reveals small cell carcinoma-like and non-small cell carcinoma-like subsets. Clin. Cancer Res. 22, 3618-3629 (2016).
-
(2016)
Clin. Cancer Res.
, vol.22
, pp. 3618-3629
-
-
Rekhtman, N.1
-
147
-
-
0001949065
-
Keynote address on biostatistics and data retrieval
-
Zelen, M. Keynote address on biostatistics and data retrieval. Cancer Chemother. Rep. 3, 31-42 (1973).
-
(1973)
Cancer Chemother. Rep.
, vol.3
, pp. 31-42
-
-
Zelen, M.1
-
148
-
-
0014413596
-
Common cytochemical and ultrastructural characteristics of cells producing polypeptide hormones (the APUD series) and their relevance to thyroid and ultimobranchial C cells and calcitonin
-
Pearse, A. G. Common cytochemical and ultrastructural characteristics of cells producing polypeptide hormones (the APUD series) and their relevance to thyroid and ultimobranchial C cells and calcitonin. Proc. R. Soc. Lond. B Biol. Sci. 170, 71-80 (1968).
-
(1968)
Proc. R. Soc. Lond. B Biol. Sci.
, vol.170
, pp. 71-80
-
-
Pearse, A.G.1
-
149
-
-
79959360314
-
History of small-cell lung cancer
-
Haddadin, S. & Perry, M. C. History of small-cell lung cancer. Clin. Lung Cancer 12, 87-93 (2011).
-
(2011)
Clin. Lung Cancer
, vol.12
, pp. 87-93
-
-
Haddadin, S.1
Perry, M.C.2
-
150
-
-
0015187933
-
A new floating cell line derived from human pulmonary carcinoma of oat cell type
-
Oboshi, S. et al. A new floating cell line derived from human pulmonary carcinoma of oat cell type. Jpn. J. Cancer Res. 62, 505-514 (1971).
-
(1971)
Jpn. J. Cancer Res.
, vol.62
, pp. 505-514
-
-
Oboshi, S.1
-
151
-
-
0016382152
-
Ectopic ACTH production in carcinoma of the lung
-
Gewirtz, G. & Yalow, R. S. Ectopic ACTH production in carcinoma of the lung. J. Clin. Invest. 53, 1022-1032 (1974).
-
(1974)
J. Clin. Invest.
, vol.53
, pp. 1022-1032
-
-
Gewirtz, G.1
Yalow, R.S.2
-
152
-
-
0018889149
-
Isolation and growth characteristics of continuous cell lines from small-cell carcinoma of the lung
-
Pettengill, O. S. et al. Isolation and growth characteristics of continuous cell lines from small-cell carcinoma of the lung. Cancer 45, 906-918 (1980).
-
(1980)
Cancer
, vol.45
, pp. 906-918
-
-
Pettengill, O.S.1
-
153
-
-
0023686773
-
Abnormalities in structure and expression of the human retinoblastoma gene in SCLC
-
Harbour, J. W. et al. Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. Science 241, 353-357 (1988).
-
(1988)
Science
, vol.241
, pp. 353-357
-
-
Harbour, J.W.1
-
154
-
-
15444374561
-
Mouse models for human lung cancer
-
Meuwissen, R. & Berns, A. Mouse models for human lung cancer. Genes Dev. 19, 643-664 (2005).
-
(2005)
Genes Dev.
, vol.19
, pp. 643-664
-
-
Meuwissen, R.1
Berns, A.2
-
155
-
-
37349068491
-
The International Association for the Study of Lung Cancer lung cancer staging project: Proposals regarding the clinical staging of small cell lung cancer in the forthcoming (seventh) edition of the tumor, node, metastasis classification for lung cancer
-
Shepherd, F. A. et al. The International Association for the Study of Lung Cancer lung cancer staging project: proposals regarding the clinical staging of small cell lung cancer in the forthcoming (seventh) edition of the tumor, node, metastasis classification for lung cancer. J. Thorac Oncol. 2, 1067-1077 (2007).
-
(2007)
J. Thorac Oncol.
, vol.2
, pp. 1067-1077
-
-
Shepherd, F.A.1
-
156
-
-
84876412243
-
Rationale for chemotherapy, immunotherapy, and checkpoint blockade in SCLC: Beyond traditional treatment approaches
-
Spigel, D. R. & Socinski, M. A. Rationale for chemotherapy, immunotherapy, and checkpoint blockade in SCLC: beyond traditional treatment approaches. J. Thorac Oncol. 8, 587-598 (2013).
-
(2013)
J. Thorac Oncol.
, vol.8
, pp. 587-598
-
-
Spigel, D.R.1
Socinski, M.A.2
-
157
-
-
85007506761
-
Rovalpituzumab tesirine, a DLL3-targeted antibody-drug conjugate, in recurrent small-cell lung cancer: A first-in-human, first-in-class, open-label, phase 1 study
-
Rudin, C. M. et al. Rovalpituzumab tesirine, a DLL3-targeted antibody-drug conjugate, in recurrent small-cell lung cancer: a first-in-human, first-in-class, open-label, phase 1 study. Lancet Oncol. 18, 42-51 (2017).
-
(2017)
Lancet Oncol.
, vol.18
, pp. 42-51
-
-
Rudin, C.M.1
-
158
-
-
79958761641
-
Cell of origin of small cell lung cancer: Inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung
-
Sutherland, K. D. et al. Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung. Cancer Cell 19, 754-764 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 754-764
-
-
Sutherland, K.D.1
-
159
-
-
84944472659
-
Roles of NOTCH1 as a therapeutic target and a biomarker for lung cancer: Controversies and perspectives
-
Guo, L., Zhang, T., Xiong, Y. & Yang, Y. Roles of NOTCH1 as a therapeutic target and a biomarker for lung cancer: controversies and perspectives. Dis. Markers 2015, 520590 (2015).
-
(2015)
Dis. Markers
, vol.2015
, pp. 520590
-
-
Guo, L.1
Zhang, T.2
Xiong, Y.3
Yang, Y.4
-
160
-
-
84938694305
-
Notch signaling in cancer: Rationale and strategies for targeting
-
Alketbi, A. & Attoub, S. Notch signaling in cancer: rationale and strategies for targeting. Curr. Cancer Drug Targets 15, 364-374 (2015).
-
(2015)
Curr. Cancer Drug Targets
, vol.15
, pp. 364-374
-
-
Alketbi, A.1
Attoub, S.2
-
161
-
-
84859098510
-
Possible roles of DLK1 in the Notch pathway during development and disease
-
Falix, F. A., Aronson, D. C., Lamers, W. H. & Gaemers, I. C. Possible roles of DLK1 in the Notch pathway during development and disease. Biochim. Biophys. Acta 1822, 988-995 (2012).
-
(2012)
Biochim. Biophys. Acta
, vol.1822
, pp. 988-995
-
-
Falix, F.A.1
Aronson, D.C.2
Lamers, W.H.3
Gaemers, I.C.4
-
162
-
-
84905963021
-
The proteins DLK1 and DLK2 modulate NOTCH1-dependent proliferation and oncogenic potential of human SK-MEL-2 melanoma cells
-
Nueda, M. L., Naranjo, A. I., Baladron, V. & Laborda, J. The proteins DLK1 and DLK2 modulate NOTCH1-dependent proliferation and oncogenic potential of human SK-MEL-2 melanoma cells. Biochim. Biophys. Acta 1843, 2674-2684 (2014).
-
(2014)
Biochim. Biophys. Acta
, vol.1843
, pp. 2674-2684
-
-
Nueda, M.L.1
Naranjo, A.I.2
Baladron, V.3
Laborda, J.4
-
163
-
-
0033918563
-
Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3
-
Dammann, R. et al. Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nat. Genet. 25, 315-319 (2000).
-
(2000)
Nat. Genet.
, vol.25
, pp. 315-319
-
-
Dammann, R.1
-
164
-
-
84987842794
-
ITPKA gene body methylation regulates gene expression and serves as an early diagnostic marker in lung and other cancers
-
Wang, Y. W. et al. ITPKA gene body methylation regulates gene expression and serves as an early diagnostic marker in lung and other cancers. J. Thorac Oncol. 11, 1469-1481 (2016).
-
(2016)
J. Thorac Oncol.
, vol.11
, pp. 1469-1481
-
-
Wang, Y.W.1
-
165
-
-
85008697782
-
Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2
-
Niu, Y. et al. Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2. Mol. Cancer 16, 5 (2017).
-
(2017)
Mol. Cancer
, vol.16
, pp. 5
-
-
Niu, Y.1
-
166
-
-
84952035123
-
Long noncoding RNA-HOTAIR affects chemoresistance by regulating HOXA1 methylation in small cell lung cancer cells
-
Fang, S. et al. Long noncoding RNA-HOTAIR affects chemoresistance by regulating HOXA1 methylation in small cell lung cancer cells. Lab. Invest. 96, 60-68 (2016).
-
(2016)
Lab. Invest.
, vol.96
, pp. 60-68
-
-
Fang, S.1
-
167
-
-
0004099835
-
-
(eds Becker, K. L. & Gazdar, A. F.)
-
Pettengill, O. S., Carney, D. N., Sorenson, G. D. & Gazdar, A. F. in The Endocrine Lung in Health and Disease (eds Becker, K. L. & Gazdar, A. F.) 460-468 (1984).
-
(1984)
The Endocrine Lung in Health and Disease
, pp. 460-468
-
-
Pettengill, O.S.1
Carney, D.N.2
Sorenson, G.D.3
Gazdar, A.F.4
-
168
-
-
33646953271
-
NCI-Navy Medical Oncology Branch cell line data base
-
Phelps, R. M. et al. NCI-Navy Medical Oncology Branch cell line data base. J. Cell. Biochem. Suppl. 24, 32-91 (1996).
-
(1996)
J. Cell. Biochem. Suppl.
, vol.24
, pp. 32-91
-
-
Phelps, R.M.1
-
169
-
-
33646962490
-
NCI series of cell lines: An historical perspective
-
Gazdar, A. F. & Minna, J. D. NCI series of cell lines: an historical perspective. J. Cell. Biochem. Suppl. 24, 1-11 (1996).
-
(1996)
J. Cell. Biochem. Suppl.
, vol.24
, pp. 1-11
-
-
Gazdar, A.F.1
Minna, J.D.2
-
170
-
-
0019279209
-
Growth of human small cell (oat cell) carcinoma of the lung in serum-free growth factor-supplemented medium
-
Simms, E., Gazdar, A. F., Abrams, P. G. & Minna, J. D. Growth of human small cell (oat cell) carcinoma of the lung in serum-free growth factor-supplemented medium. Cancer Res. 40, 4356-4363 (1980).
-
(1980)
Cancer Res.
, vol.40
, pp. 4356-4363
-
-
Simms, E.1
Gazdar, A.F.2
Abrams, P.G.3
Minna, J.D.4
-
171
-
-
0022335729
-
The serum-free establishment and in vitro growth properties of classic and variant small cell lung cancer cell lines
-
Carney, D. N., Bepler, G. & Gazdar, A. F. The serum-free establishment and in vitro growth properties of classic and variant small cell lung cancer cell lines. Recent Results Cancer Res. 99, 157-166 (1985).
-
(1985)
Recent Results Cancer Res.
, vol.99
, pp. 157-166
-
-
Carney, D.N.1
Bepler, G.2
Gazdar, A.F.3
-
172
-
-
10844284696
-
Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins
-
Ramirez, R. D. et al. Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res. 64, 9027-9034 (2004).
-
(2004)
Cancer Res.
, vol.64
, pp. 9027-9034
-
-
Ramirez, R.D.1
-
173
-
-
84876207852
-
Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations
-
Sato, M. et al. Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations. Mol. Cancer Res. 11, 638-650 (2013).
-
(2013)
Mol. Cancer Res.
, vol.11
, pp. 638-650
-
-
Sato, M.1
-
174
-
-
84875803391
-
Mouse models of cancer
-
Berns, A. & Barbacid, M. Mouse models of cancer. Mol. Oncol. 7, 143-145 (2013).
-
(2013)
Mol. Oncol.
, vol.7
, pp. 143-145
-
-
Berns, A.1
Barbacid, M.2
-
175
-
-
84962522570
-
From mice to men and back: An assessment of preclinical model systems for the study of lung cancers
-
Gazdar, A. F., Hirsch, F. R. & Minna, J. D. From mice to men and back: an assessment of preclinical model systems for the study of lung cancers. J. Thorac Oncol. 11, 287-299 (2016).
-
(2016)
J. Thorac Oncol.
, vol.11
, pp. 287-299
-
-
Gazdar, A.F.1
Hirsch, F.R.2
Minna, J.D.3
-
176
-
-
84861879404
-
Genetically engineered mouse models: Closing the gap between preclinical data and trial outcomes
-
Singh, M., Murriel, C. L. & Johnson, L. Genetically engineered mouse models: closing the gap between preclinical data and trial outcomes. Cancer Res. 72, 2695-2700 (2012).
-
(2012)
Cancer Res.
, vol.72
, pp. 2695-2700
-
-
Singh, M.1
Murriel, C.L.2
Johnson, L.3
-
177
-
-
84929989581
-
Preclinical murine models for lung cancer: Clinical trial applications
-
Kellar, A., Egan, C. & Morris, D. Preclinical murine models for lung cancer: clinical trial applications. BioMed Res. Int. 2015, 621324 (2015).
-
(2015)
BioMed Res. Int.
, vol.2015
, pp. 621324
-
-
Kellar, A.1
Egan, C.2
Morris, D.3
-
178
-
-
84884318689
-
Mouse models of chemically-induced lung carcinogenesis
-
Vikis, H. G., Rymaszewski, A. L. & Tichelaar, J. W. Mouse models of chemically-induced lung carcinogenesis. Front. Biosci. 5, 939-946 (2013).
-
(2013)
Front. Biosci.
, vol.5
, pp. 939-946
-
-
Vikis, H.G.1
Rymaszewski, A.L.2
Tichelaar, J.W.3
-
179
-
-
77952794331
-
Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma
-
Schaffer, B. E. et al. Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma. Cancer Res. 70, 3877-3883 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 3877-3883
-
-
Schaffer, B.E.1
-
180
-
-
85012031704
-
Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation
-
Lázaro, S. et al. Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation. Oncotarget 8, 4373-4386 (2016).
-
(2016)
Oncotarget
, vol.8
, pp. 4373-4386
-
-
Lázaro, S.1
-
181
-
-
84873808119
-
Evaluation of novel orthotopic nude mouse models for human small-cell lung cancer
-
Isobe, T. et al. Evaluation of novel orthotopic nude mouse models for human small-cell lung cancer. J. Thorac Oncol. 8, 140-146 (2013).
-
(2013)
J. Thorac Oncol.
, vol.8
, pp. 140-146
-
-
Isobe, T.1
-
182
-
-
74349117865
-
Clinical relevance of human cancer xenografts as a tool for preclinical assessment: Example of in-vivo evaluation of topotecan-based chemotherapy in a panel of human small-cell lung cancer xenografts
-
Némati, F. et al. Clinical relevance of human cancer xenografts as a tool for preclinical assessment: example of in-vivo evaluation of topotecan-based chemotherapy in a panel of human small-cell lung cancer xenografts. Anticancer Drugs 21, 25-32 (2010).
-
(2010)
Anticancer Drugs
, vol.21
, pp. 25-32
-
-
Némati, F.1
-
183
-
-
84928092645
-
New metastatic model of human small-cell lung cancer by orthotopic transplantation in mice
-
Sakamoto, S. et al. New metastatic model of human small-cell lung cancer by orthotopic transplantation in mice. Cancer Sci. 106, 367-374 (2015).
-
(2015)
Cancer Sci.
, vol.106
, pp. 367-374
-
-
Sakamoto, S.1
-
184
-
-
0019378229
-
Intracranial growth of pulmonary small cell carcinoma cells in nude athymic mice
-
Chambers, W. F., Pettengill, O. S. & Sorenson, G. D. Intracranial growth of pulmonary small cell carcinoma cells in nude athymic mice. Exp. Cell Biol. 49, 90-97 (1981).
-
(1981)
Exp. Cell Biol.
, vol.49
, pp. 90-97
-
-
Chambers, W.F.1
Pettengill, O.S.2
Sorenson, G.D.3
-
185
-
-
0019847006
-
Heterotransplantation of small-cell carcinoma of the lung into nude mice: Comparison of intracranial and subcutaneous routes
-
Gazdar, A. F., Carney, D. N., Sims, H. L. & Simmons, A. Heterotransplantation of small-cell carcinoma of the lung into nude mice: comparison of intracranial and subcutaneous routes. Int. J. Cancer 28, 777-783 (1981).
-
(1981)
Int. J. Cancer
, vol.28
, pp. 777-783
-
-
Gazdar, A.F.1
Carney, D.N.2
Sims, H.L.3
Simmons, A.4
-
186
-
-
84893637270
-
One mouse, one patient paradigm: New avatars of personalized cancer therapy
-
Malaney, P., Nicosia, S. V. & Dave, V. One mouse, one patient paradigm: new avatars of personalized cancer therapy. Cancer Lett. 344, 1-12 (2014).
-
(2014)
Cancer Lett.
, vol.344
, pp. 1-12
-
-
Malaney, P.1
Nicosia, S.V.2
Dave, V.3
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