-
1
-
-
26644438582
-
Small-cell lung cancer
-
Jackman DM and Johnson BE. Small-cell lung cancer. Lancet. 2005; 366:1385-1396.
-
(2005)
Lancet.
, vol.366
, pp. 1385-1396
-
-
Jackman, D.M.1
Johnson, B.E.2
-
2
-
-
84938132350
-
Comprehensive genomic profiles of small cell lung cancer
-
George J, Lim JS, Jang SJ, Cun Y, Ozretic L, Kong G, Leenders F, Lu X, Fernandez-Cuesta L, Bosco G, Muller C, Dahmen I, Jahchan NS, Park KS, Yang D, Karnezis AN, et al. Comprehensive genomic profiles of small cell lung cancer. Nature. 2015; 524:47-53.
-
(2015)
Nature.
, vol.524
, pp. 47-53
-
-
George, J.1
Lim, J.S.2
Jang, S.J.3
Cun, Y.4
Ozretic, L.5
Kong, G.6
Leenders, F.7
Lu, X.8
Fernandez-Cuesta, L.9
Bosco, G.10
Muller, C.11
Dahmen, I.12
Jahchan, N.S.13
Park, K.S.14
Yang, D.15
Karnezis, A.N.16
-
3
-
-
84866849548
-
Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
-
Rudin CM, Durinck S, Stawiski EW, Poirier JT, Modrusan Z, Shames DS, Bergbower EA, Guan Y, Shin J, Guillory J, Rivers CS, Foo CK, Bhatt D, Stinson J, Gnad F, Haverty PM, et al. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nature genetics. 2012.
-
(2012)
Nature genetics.
-
-
Rudin, C.M.1
Durinck, S.2
Stawiski, E.W.3
Poirier, J.T.4
Modrusan, Z.5
Shames, D.S.6
Bergbower, E.A.7
Guan, Y.8
Shin, J.9
Guillory, J.10
Rivers, C.S.11
Foo, C.K.12
Bhatt, D.13
Stinson, J.14
Gnad, F.15
Haverty, P.M.16
-
4
-
-
0141523025
-
Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model
-
Meuwissen R, Linn SC, Linnoila RI, Zevenhoven J, Mooi WJ and Berns A. Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model. Cancer Cell. 2003; 4:181-189.
-
(2003)
Cancer Cell.
, vol.4
, pp. 181-189
-
-
Meuwissen, R.1
Linn, S.C.2
Linnoila, R.I.3
Zevenhoven, J.4
Mooi, W.J.5
Berns, A.6
-
5
-
-
79958761641
-
Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung
-
Sutherland KD, Proost N, Brouns I, Adriaensen D, Song JY and Berns A. Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung. Cancer Cell. 2011; 19:754-764.
-
(2011)
Cancer Cell.
, vol.19
, pp. 754-764
-
-
Sutherland, K.D.1
Proost, N.2
Brouns, I.3
Adriaensen, D.4
Song, J.Y.5
Berns, A.6
-
6
-
-
84896333670
-
Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing
-
McFadden DG, Papagiannakopoulos T, Taylor-Weiner A, Stewart C, Carter SL, Cibulskis K, Bhutkar A, McKenna A, Dooley A, Vernon A, Sougnez C, Malstrom S, Heimann M, Park J, Chen F, Farago AF, et al. Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing. Cell. 2014; 156:1298-1311.
-
(2014)
Cell.
, vol.156
, pp. 1298-1311
-
-
McFadden, D.G.1
Papagiannakopoulos, T.2
Taylor-Weiner, A.3
Stewart, C.4
Carter, S.L.5
Cibulskis, K.6
Bhutkar, A.7
McKenna, A.8
Dooley, A.9
Vernon, A.10
Sougnez, C.11
Malstrom, S.12
Heimann, M.13
Park, J.14
Chen, F.15
Farago, A.F.16
-
7
-
-
84974605091
-
Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer
-
Kim DW, Wu N, Kim YC, Cheng PF, Basom R, Kim D, Dunn CT, Lee AY, Kim K, Lee CS, Singh A, Gazdar AF, Harris CR, Eisenman RN, Park KS and MacPherson D. Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer. Genes Dev. 2016; 30:1289-1299.
-
(2016)
Genes Dev.
, vol.30
, pp. 1289-1299
-
-
Kim, D.W.1
Wu, N.2
Kim, Y.C.3
Cheng, P.F.4
Basom, R.5
Kim, D.6
Dunn, C.T.7
Lee, A.Y.8
Kim, K.9
Lee, C.S.10
Singh, A.11
Gazdar, A.F.12
Harris, C.R.13
Eisenman, R.N.14
Park, K.S.15
MacPherson, D.16
-
8
-
-
84893809132
-
Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells
-
Huijbers IJ, Bin Ali R, Pritchard C, Cozijnsen M, Kwon MC, Proost N, Song JY, de Vries H, Badhai J, Sutherland K, Krimpenfort P, Michalak EM, Jonkers J and Berns A. Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells. EMBO molecular medicine. 2014; 6:212-225.
-
(2014)
EMBO molecular medicine.
, vol.6
, pp. 212-225
-
-
Huijbers, I.J.1
Bin Ali, R.2
Pritchard, C.3
Cozijnsen, M.4
Kwon, M.C.5
Proost, N.6
Song, J.Y.7
de Vries, H.8
Badhai, J.9
Sutherland, K.10
Krimpenfort, P.11
Michalak, E.M.12
Jonkers, J.13
Berns, A.14
-
9
-
-
84900437332
-
PTEN is a Potent Suppressor of Small Cell Lung Cancer
-
Cui M, Augert A, Rongione M, Conkrite K, Parazzoli S, Nikitin AY, Ingolia N and Macpherson D. PTEN is a Potent Suppressor of Small Cell Lung Cancer. Mol Cancer Res. 2014.
-
(2014)
Mol Cancer Res.
-
-
Cui, M.1
Augert, A.2
Rongione, M.3
Conkrite, K.4
Parazzoli, S.5
Nikitin, A.Y.6
Ingolia, N.7
Macpherson, D.8
-
10
-
-
79960463418
-
Nuclear factor I/B is an oncogene in small cell lung cancer
-
Dooley AL, Winslow MM, Chiang DY, Banerji S, Stransky N, Dayton TL, Snyder EL, Senna S, Whittaker CA, Bronson RT, Crowley D, Barretina J, Garraway L, Meyerson M and Jacks T. Nuclear factor I/B is an oncogene in small cell lung cancer. Genes & development. 2011; 25:1470-1475.
-
(2011)
Genes & development.
, vol.25
, pp. 1470-1475
-
-
Dooley, A.L.1
Winslow, M.M.2
Chiang, D.Y.3
Banerji, S.4
Stransky, N.5
Dayton, T.L.6
Snyder, E.L.7
Senna, S.8
Whittaker, C.A.9
Bronson, R.T.10
Crowley, D.11
Barretina, J.12
Garraway, L.13
Meyerson, M.14
Jacks, T.15
-
11
-
-
11844283949
-
The transcription factor gene Nfib is essential for both lung maturation and brain development
-
Steele-Perkins G, Plachez C, Butz KG, Yang G, Bachurski CJ, Kinsman SL, Litwack ED, Richards LJ and Gronostajski RM. The transcription factor gene Nfib is essential for both lung maturation and brain development. Mol Cell Biol. 2005; 25:685-698.
-
(2005)
Mol Cell Biol.
, vol.25
, pp. 685-698
-
-
Steele-Perkins, G.1
Plachez, C.2
Butz, K.G.3
Yang, G.4
Bachurski, C.J.5
Kinsman, S.L.6
Litwack, E.D.7
Richards, L.J.8
Gronostajski, R.M.9
-
12
-
-
0036177886
-
Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia
-
Grunder A, Ebel TT, Mallo M, Schwarzkopf G, Shimizu T, Sippel AE and Schrewe H. Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mech Dev. 2002; 112:69-77.
-
(2002)
Mech Dev.
, vol.112
, pp. 69-77
-
-
Grunder, A.1
Ebel, T.T.2
Mallo, M.3
Schwarzkopf, G.4
Shimizu, T.5
Sippel, A.E.6
Schrewe, H.7
-
13
-
-
84919495606
-
Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor
-
Christensen CL, Kwiatkowski N, Abraham BJ, Carretero J, Al-Shahrour F, Zhang T, Chipumuro E, Herter-Sprie GS, Akbay EA, Altabef A, Zhang J, Shimamura T, Capelletti M, Reibel JB, Cavanaugh JD, Gao P, et al. Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor. Cancer Cell. 2014; 26:909-922.
-
(2014)
Cancer Cell.
, vol.26
, pp. 909-922
-
-
Christensen, C.L.1
Kwiatkowski, N.2
Abraham, B.J.3
Carretero, J.4
Al-Shahrour, F.5
Zhang, T.6
Chipumuro, E.7
Herter-Sprie, G.S.8
Akbay, E.A.9
Altabef, A.10
Zhang, J.11
Shimamura, T.12
Capelletti, M.13
Reibel, J.B.14
Cavanaugh, J.D.15
Gao, P.16
-
14
-
-
84989936333
-
ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs
-
Borromeo MD, Savage TK, Kollipara RK, He M, Augustyn A, Osborne JK, Girard L, Minna JD, Gazdar AF, Cobb MH and Johnson JE. ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs. Cell reports. 2016.
-
(2016)
Cell reports.
-
-
Borromeo, M.D.1
Savage, T.K.2
Kollipara, R.K.3
He, M.4
Augustyn, A.5
Osborne, J.K.6
Girard, L.7
Minna, J.D.8
Gazdar, A.F.9
Cobb, M.H.10
Johnson, J.E.11
-
15
-
-
84891953718
-
Discovery and characterization of super-enhancerassociated dependencies in diffuse large B cell lymphoma
-
Chapuy B, McKeown MR, Lin CY, Monti S, Roemer MG, Qi J, Rahl PB, Sun HH, Yeda KT, Doench JG, Reichert E, Kung AL, Rodig SJ, Young RA, Shipp MA and Bradner JE. Discovery and characterization of super-enhancerassociated dependencies in diffuse large B cell lymphoma. Cancer Cell. 2013; 24:777-790.
-
(2013)
Cancer Cell.
, vol.24
, pp. 777-790
-
-
Chapuy, B.1
McKeown, M.R.2
Lin, C.Y.3
Monti, S.4
Roemer, M.G.5
Qi, J.6
Rahl, P.B.7
Sun, H.H.8
Yeda, K.T.9
Doench, J.G.10
Reichert, E.11
Kung, A.L.12
Rodig, S.J.13
Young, R.A.14
Shipp, M.A.15
Bradner, J.E.16
-
16
-
-
84888015137
-
Super-enhancers in the control of cell identity and disease
-
Hnisz D, Abraham BJ, Lee TI, Lau A, Saint-Andre V, Sigova AA, Hoke HA and Young RA. Super-enhancers in the control of cell identity and disease. Cell. 2013; 155:934-947.
-
(2013)
Cell.
, vol.155
, pp. 934-947
-
-
Hnisz, D.1
Abraham, B.J.2
Lee, T.I.3
Lau, A.4
Saint-Andre, V.5
Sigova, A.A.6
Hoke, H.A.7
Young, R.A.8
-
17
-
-
84904963991
-
Targeting transcription regulation in cancer with a covalent CDK7 inhibitor
-
Kwiatkowski N, Zhang T, Rahl PB, Abraham BJ, Reddy J, Ficarro SB, Dastur A, Amzallag A, Ramaswamy S, Tesar B, Jenkins CE, Hannett NM, McMillin D, Sanda T, Sim T, Kim ND, et al. Targeting transcription regulation in cancer with a covalent CDK7 inhibitor. Nature. 2014; 511:616-620.
-
(2014)
Nature.
, vol.511
, pp. 616-620
-
-
Kwiatkowski, N.1
Zhang, T.2
Rahl, P.B.3
Abraham, B.J.4
Reddy, J.5
Ficarro, S.B.6
Dastur, A.7
Amzallag, A.8
Ramaswamy, S.9
Tesar, B.10
Jenkins, C.E.11
Hannett, N.M.12
McMillin, D.13
Sanda, T.14
Sim, T.15
Kim, N.D.16
-
18
-
-
58149218240
-
High-resolution mapping of copy-number alterations with massively parallel sequencing
-
Chiang DY, Getz G, Jaffe DB, O'Kelly MJ, Zhao X, Carter SL, Russ C, Nusbaum C, Meyerson M and Lander ES. High-resolution mapping of copy-number alterations with massively parallel sequencing. Nat Methods. 2009; 6:99-103.
-
(2009)
Nat Methods.
, vol.6
, pp. 99-103
-
-
Chiang, D.Y.1
Getz, G.2
Jaffe, D.B.3
O'Kelly, M.J.4
Zhao, X.5
Carter, S.L.6
Russ, C.7
Nusbaum, C.8
Meyerson, M.9
Lander, E.S.10
-
19
-
-
64849083125
-
CNV-seq, a new method to detect copy number variation using high-throughput sequencing
-
Xie C and Tammi MT. CNV-seq, a new method to detect copy number variation using high-throughput sequencing. BMC Bioinformatics. 2009; 10:80.
-
(2009)
BMC Bioinformatics.
, vol.10
, pp. 80
-
-
Xie, C.1
Tammi, M.T.2
-
20
-
-
84929949436
-
The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung
-
Gazdar AF, Savage TK, Johnson JE, Berns A, Sage J, Linnoila RI, MacPherson D, McFadden DG, Farago A, Jacks T, Travis WD and Brambilla E. The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung. Journal of thoracic oncology. 2015; 10:553-564.
-
(2015)
Journal of thoracic oncology.
, vol.10
, pp. 553-564
-
-
Gazdar, A.F.1
Savage, T.K.2
Johnson, J.E.3
Berns, A.4
Sage, J.5
Linnoila, R.I.6
MacPherson, D.7
McFadden, D.G.8
Farago, A.9
Jacks, T.10
Travis, W.D.11
Brambilla, E.12
-
21
-
-
84978379634
-
Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility
-
Denny SK, Yang D, Chuang CH, Brady JJ, Lim JS, Gruner BM, Chiou SH, Schep AN, Baral J, Hamard C, Antoine M, Wislez M, Kong CS, Connolly AJ, Park KS, Sage J, et al. Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility. Cell. 2016; 166:328-342.
-
(2016)
Cell.
, vol.166
, pp. 328-342
-
-
Denny, S.K.1
Yang, D.2
Chuang, C.H.3
Brady, J.J.4
Lim, J.S.5
Gruner, B.M.6
Chiou, S.H.7
Schep, A.N.8
Baral, J.9
Hamard, C.10
Antoine, M.11
Wislez, M.12
Kong, C.S.13
Connolly, A.J.14
Park, K.S.15
Sage, J.16
-
22
-
-
84978388629
-
Transcription Factor NFIB Is a Driver of Small Cell Lung Cancer Progression in Mice and Marks Metastatic Disease in Patients
-
Semenova EA, Kwon MC, Monkhorst K, Song JY, Bhaskaran R, Krijgsman O, Kuilman T, Peters D, Buikhuisen WA, Smit EF, Pritchard C, Cozijnsen M, van der Vliet J, Zevenhoven J, Lambooij JP, Proost N, et al. Transcription Factor NFIB Is a Driver of Small Cell Lung Cancer Progression in Mice and Marks Metastatic Disease in Patients. Cell reports. 2016; 16:631-643.
-
(2016)
Cell reports.
, vol.16
, pp. 631-643
-
-
Semenova, E.A.1
Kwon, M.C.2
Monkhorst, K.3
Song, J.Y.4
Bhaskaran, R.5
Krijgsman, O.6
Kuilman, T.7
Peters, D.8
Buikhuisen, W.A.9
Smit, E.F.10
Pritchard, C.11
Cozijnsen, M.12
van der Vliet, J.13
Zevenhoven, J.14
Lambooij, J.P.15
Proost, N.16
-
23
-
-
0344629659
-
Nuclear factor I/thyroid transcription factor 1 interactions modulate surfactant protein C transcription
-
Bachurski CJ, Yang GH, Currier TA, Gronostajski RM and Hong D. Nuclear factor I/thyroid transcription factor 1 interactions modulate surfactant protein C transcription. Mol Cell Biol. 2003; 23:9014-9024.
-
(2003)
Mol Cell Biol.
, vol.23
, pp. 9014-9024
-
-
Bachurski, C.J.1
Yang, G.H.2
Currier, T.A.3
Gronostajski, R.M.4
Hong, D.5
-
24
-
-
0032541050
-
Nuclear factor I (NFI) isoforms differentially activate simple versus complex NFI-responsive promoters
-
Chaudhry AZ, Vitullo AD and Gronostajski RM. Nuclear factor I (NFI) isoforms differentially activate simple versus complex NFI-responsive promoters. J Biol Chem. 1998; 273:18538-18546.
-
(1998)
J Biol Chem.
, vol.273
, pp. 18538-18546
-
-
Chaudhry, A.Z.1
Vitullo, A.D.2
Gronostajski, R.M.3
-
25
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen M and Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci U S A. 1992; 89:5547-5551.
-
(1992)
Proc Natl Acad Sci U S A.
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
26
-
-
65449136284
-
TopHat: discovering splice junctions with RNA-Seq
-
Trapnell C, Pachter L and Salzberg SL. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics. 2009; 25:1105-1111.
-
(2009)
Bioinformatics.
, vol.25
, pp. 1105-1111
-
-
Trapnell, C.1
Pachter, L.2
Salzberg, S.L.3
-
27
-
-
75249087100
-
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
-
Robinson MD, McCarthy DJ and Smyth GK. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics. 2010; 26:139-140.
-
(2010)
Bioinformatics.
, vol.26
, pp. 139-140
-
-
Robinson, M.D.1
McCarthy, D.J.2
Smyth, G.K.3
-
28
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang da W, Sherman BT and Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 2009; 4:44-57.
-
(2009)
Nat Protoc.
, vol.4
, pp. 44-57
-
-
Huang da, W.1
Sherman, B.T.2
Lempicki, R.A.3
|