Selective tropism of seneca valley virus for variant subtype small cell lung cancer

Journal of the National Cancer Institute

Volumn 105, Issue 14, 2013, Pages 1059-1065

  Poirier, J T ^a   Dobromilskaya, Irina ^a   Moriarty, Whei F ^a   Peacock, Craig D ^a   Hann, Christine L ^a   Rudin, Charles M ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROGENIC DIFFERENTIATION FACTOR; TRANSCRIPTION FACTOR MASH1; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LUNG SMALL CELL CANCER; MOUSE; NONHUMAN; PICORNAVIRUS; PRIORITY JOURNAL; SENECA VALLEY VIRUS; SENSITIVITY AND SPECIFICITY; TROPISM; VIRAL GENE THERAPY;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARCINOMA, SMALL CELL; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION PROFILING; LUNG NEOPLASMS; MICE; MICE, INBRED STRAINS; MICE, SCID; ONCOLYTIC VIRUSES; PICORNAVIRIDAE; PREDICTIVE VALUE OF TESTS; PROTEIN ARRAY ANALYSIS; TRANSPLANTATION, HETEROLOGOUS; TROPISM;

EID: 84880559818     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/djt130     Document Type: Article

References (34)

1. Wistuba I, Gazdar AF, Minna JD. Molecular genetics of small cell lung carcinoma. Semin Oncol. 2001;28(2 suppl 4):3-13. (Pubitemid 32730372)
2. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin. 2012;62(1):10-29.
3. Oze I, Hotta K, Kiura K, et al. Twenty-seven years of phase III trials for patients with extensive disease small-cell lung cancer: disappointing results. PLoS One. 2009;4(11):e7835.
4. Carney DN, Gazdar AF, Bepler G, et al. Establishment and identification of small cell lung cancer cell lines having classic and variant features. Cancer Res. 1985;45(6):2913-2923. (Pubitemid 15232769)
5. Pedersen N, Mortensen S, Sorensen SB, et al. Transcriptional gene expression profiling of small cell lung cancer cells. Cancer Res. 2003;63(8):1943-1953. (Pubitemid 36460862)
6. Carney DN, Mitchell JB, Kinsella TJ. In vitro radiation and chemotherapy sensitivity of established cell lines of human small cell lung cancer and its large cell morphological variants. Cancer Res. 1983;43(6):2806-2811. (Pubitemid 13100550)
7. Kraus AC, Ferber I, Bachmann SO, et al. In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathways. Oncogene. 2002;21(57):8683-8695. (Pubitemid 36132389)
8. Radice PA, Matthews MJ, Ihde DC, et al. The clinical behavior of "mixed" small cell/ large cell bronchogenic carcinoma compared to "pure" small cell subtypes. Cancer. 1982;50(12):2894-2902. (Pubitemid 13220802)
9. Brambilla E, Moro D, Gazzeri S, et al. Cytotoxic chemotherapy induces cell differentiation in small-cell lung carcinoma. J Clin Oncol. 1991;9(1):50-61.
10. Reddy PS, Burroughs KD, Hales LM, et al. Seneca Valley virus, a systemically deliverable oncolytic picornavirus, and the treatment of neuroendocrine cancers. J Natl Cancer Inst. 2007;99(21):1623-1633.
11. Morton CL, Houghton PJ, Kolb EA, et al. Initial testing of the replication competent Seneca Valley virus (NTX-010) by the pediatric preclinical testing program. Pediatr Blood Cancer. 2010;55(2):295-303.
12. Yu L, Baxter PA, Zhao X, et al. A single intravenous injection of oncolytic picornavirus SVV-001 eliminates medulloblastomas in primary tumor-based orthotopic xenograft mouse models. Neuro Oncol. 2011;13(1):14-27.
13. Wadhwa L, Hurwitz MY, Chevez-Barrios P, et al. Treatment of invasive retinoblastoma in a murine model using an oncolytic picornavirus. Cancer Res. 2007;67(22):10653-10656. (Pubitemid 350145889)
14. Rudin CM, Poirier JT, Senzer NN, et al. Phase I clinical study of Seneca Valley Virus (SVV-001), a replication-competent picornavirus, in advanced solid tumors with neuroendocrine features. Clin Cancer Res. 2011;17(4):888-895.
15. Venkataraman S, Reddy S P, Loo J, et al. Structure of Seneca Valley virus-001: an oncolytic picornavirus representing a new genus. Structure. 2008;16(10):1555-1561.
16. Hann CL, Daniel VC, Sugar EA, et al. Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer. Cancer Res. 2008;68(7):2321-2328. (Pubitemid 351521806)
17. Daniel VC, Marchionni L, Hierman JS, et al. A primary xenograft model of small-cell lung cancer reveals irreversible changes in gene expression imposed by culture in vitro. Cancer Res. 2009;69(8):3364-3373.
18. Poirier JT, Reddy PS, Idamakanti N, et al. Characterization of a full-length infectious cDNA clone and a GFP reporter derivative of the oncolytic picornavirus SVV-001. J Gen Virol. 2012;93(Pt 12):2606-2613.
19. Kim EJ, Ables JL, Dickel LK, et al. Ascl1 (Mash1) defines cells with long-term neurogenic potential in subgranular and subventricular zones in adult mouse brain. PLoS One. 2011;6(3):e18472.
20. Neptune ER, Podowski M, Calvi C, et al. Targeted disruption of NeuroD, a proneural basic helix-loop-helix factor, impairs distal lung formation and neuroendocrine morphology in the neonatal lung. J Biol Chem. 2008;283(30):21160-21169.
21. Borges M, Linnoila RI, van de Velde HJ, et al. An achaete-scute homologue essential for neuroendocrine differentiation in the lung. Nature. 1997;386(6627):852-855. (Pubitemid 27181261)
22. Ito T, Udaka N, Yazawa T, et al. Basic helixloop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development. 2000;127 (18):3913-3921.
23. Shida T, Furuya M, Kishimoto T, et al. The expression of NeuroD and mASH1 in the gastroenteropancreatic neuroendocrine tumors. Mod Pathol. 2008;21(11):1363-1370.
24. Westerman BA, Neijenhuis S, Poutsma A, et al. Quantitative reverse transcription-polymerase chain reaction measurement of HASH1 (ASCL1), a marker for small cell lung carcinomas with neuroendocrine features. Clin Cancer Res. 2002;8(4):1082-1086. (Pubitemid 35177359)
25. Jiang T, Collins BJ, Jin N, et al. Achaete-scute complex homologue 1 regulates tumorinitiating capacity in human small cell lung cancer. Cancer Res. 2009;69(3):845-854.
26. Geman D, d'Avignon C, Naiman DQ, et al. Classifying gene expression profiles from pairwise mRNA comparisons. Stat Appl Genet Mol Biol. 2004;3:Article19.
27. Park KS, Martelotto LG, Peifer M, et al. A crucial requirement for Hedgehog signaling in small cell lung cancer. Nat Med. 2011;17(11):1504-1508.
28. Edgar R, Domrachev M, Lash AE. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res. 2002;30(1):207-210. (Pubitemid 34679544)
29. Gentleman RC, Carey VJ, Bates DM, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 2004;5(10):R80.
30. Smyth GK. Limma: linear models for micro-array data. In: Gentleman R, Carey V, Dudoit S, et al., eds. Bioinformatics and Computational Biology Solutions Using R and Bioconductor. New York: Springer; 2005:397-420.
31. Pattyn F, Robbrecht P, De Paepe A, et al. RTPrimerDB: the real-time PCR primer and probe database, major update 2006. Nucleic Acids Res. 2006;34(database issue):D684-688.
32. Nissan X, Larribere L, Saidani M, et al. Functional melanocytes derived from human pluripotent stem cells engraft into pluristratified epidermis. Proc Natl Acad Sci U S A. 2011;108(36):14861-14866.
33. Van Gele M, Boyle GM, Cook AL, et al. Gene-expression profiling reveals distinct expression patterns for classic versus variant Merkel cell phenotypes and new classifier genes to distinguish Merkel cell from small-cell lung carcinoma. Oncogene. 2004; 23(15):2732-2742. (Pubitemid 38586327)
34. Leek JT. The tspair package for finding top scoring pair classifiers in R. Bioinformatics. 2009;25(9):1203-1204. Foundation