Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

Nature Genetics

Volumn 44, Issue 10, 2012, Pages 1104-1110

  Peifer, Martin ^a   Fernández Cuesta, Lynnette ^a   Sos, Martin L ^a   George, Julie ^a   Seidel, Danila ^a   Kasper, Lawryn H ^b   Plenker, Dennis ^a   Leenders, Frauke ^a   Sun, Ruping ^c   Zander, Thomas ^a   Menon, Roopika ^d   Koker, Mirjam ^a   Dahmen, Ilona ^a   Müller, Christian ^a   Di Cerbo, Vincenzo ^e   Schildhaus, Hans Ulrich ^a   Altmüller, Janine ^f   Baessmann, Ingelore ^f   Becker, Christian ^f   De Wilde, Bram ^g   Vandesompele, Jo ^g   Böhm, Diana ^d   Ansén, Sascha ^a   Gabler, Franziska ^a   Wilkening, Ines ^a   Heynck, Stefanie ^a   Heuckmann, Johannes M ^a   Lu, Xin ^a   Carter, Scott L ^h   Cibulskis, Kristian ^h   Banerji, Shantanu ^h   Getz, Gad ^h   Park, Kwon Sik ⁱ   Rauh, Daniel ^j   Grütter, Christian ^j   Fischer, Matthias ^a,k   Pasqualucci, Laura ^l   Wright, Gavin ^m   Wainer, Zoe ^m   Russell, Prudence ⁿ   Petersen, Iver ^o   Chen, Yuan ^o   Stoelben, Erich ^p   Ludwig, Corinna ^p   Schnabel, Philipp ^q   Hoffmann, Hans ^r   Muley, Thomas ^r   Brockmann, Michael ^s   Engel Riedel, Walburga ^p   Muscarella, Lucia A ^t   Fazio, Vito M ^t   Groen, Harry ^u   Timens, Wim ^u   Sietsma, Hannie ^u   Thunnissen, Erik ^v   Smit, Egber ^v   Heideman, Daniëlle A M ^v   Snijders, Peter J F ^v   Cappuzzo, Federico ^w   Ligorio, Claudia ^x   Damiani, Stefania ^x   Field, John ^y   Solberg, Steinar ^z   Brustugun, Odd Terje ^z,aa   Lund Iversen, Marius ^z   Sänger, Jörg ^ab   Clement, Joachim H ^o   Soltermann, Alex ^ac   Moch, Holger ^ac   Weder, Walter ^ac   Solomon, Benjamin ^ad   Soria, Jean Charles ^ae   Validire, Pierre ^af   Besse, Benjamin ^ae   Brambilla, Elisabeth ^ag,ah   Brambilla, Christian ^ag,ah   Lantuejoul, Sylvie ^ag,ah   Lorimier, Philippe ^ag   Schneider, Peter M ^a   Hallek, Michael ^a   Pao, William ^ai   Meyerson, Matthew ^h,aj,ak   Sage, Julien ⁱ   Shendure, Jay ^al   Schneider, Robert ^e,am   Büttner, Reinhard ^a   Wolf, Jürgen ^a   Nürnberg, Peter ^a,f   Perner, Sven ^d   Heukamp, Lukas C ^a   Brindle, Paul K ^b   Haas, Stefan ^c   Thomas, Roman K ^a   more..

^a UNIVERSITY OF COLOGNE   (Germany)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^d UNIVERSITY HOSPITAL BONN   (Germany)

^e MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^f UNIVERSITY OF COLOGNE   (Germany)

^g GHENT UNIVERSITY HOSPITAL   (Belgium)

^h BROAD INSTITUTE OF MIT AND HARVARD   (United States)

ⁱ STANFORD UNIVERSITY   (United States)

^j TU DORTMUND UNIVERSITY   (Germany)

^k UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^l Och Spine at New York Presbyterian Hospitals   (United States)

^m UNIVERSITY OF MELBOURNE   (Australia)

ⁿ ST VINCENT S HOSPITAL   (Australia)

^o JENA UNIVERSITY HOSPITAL   (Germany)

^p Lungenklinik Merheim   (Germany)

^q Institute of Pathology   (Germany)

^r Casa Sollievo della Sofferenza ^*  (Germany)

^s Hospital Merheim   (Germany)

^t CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^u UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^v VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^w Ospedale Civile   (Italy)

^x UNIVERSITY OF BOLOGNA   (Italy)

^y UNIVERSITY OF LIVERPOOL   (United Kingdom)

^z OSLO UNIVERSITY HOSPITAL   (Norway)

^aa UNIVERSITY OF OSLO   (Norway)

^ab Institute for Pathology Bad Berka   (Germany)

^ac UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^ad PETER MACCALLUM CANCER CENTRE   (Australia)

^ae INSTITUT GUSTAVE ROUSSY   (France)

^af INSTITUT MUTUALISTE MONTSOURIS   (France)

^ag UNIV GRENOBLE ALPES   (France)

^ah INSTITUT ALBERT BONNIOT   (France)

^ai VANDERBILT INGRAM CANCER CENTER   (United States)

^aj HARVARD MEDICAL SCHOOL   (United States)

^ak DANA FARBER CANCER INSTITUTE   (United States)

^al UNIVERSITY OF WASHINGTON   (United States)

^am UNIVERSITÉ DE STRASBOURG   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 1;

ARTICLE; CLASSIFICATION ALGORITHM; CONTROLLED STUDY; COPY NUMBER VARIATION; CREBBP GENE; EP300 GENE; EPHA7 GENE; FGFR1 GENE; FRAMESHIFT MUTATION; GENE AMPLIFICATION; GENE DELETION; GENE INACTIVATION; GENE INSERTION; GENE MUTATION; GENE REARRANGEMENT; GENOME ANALYSIS; HETEROZYGOSITY LOSS; HISTONE MODIFICATION; HUMAN; HUMAN TISSUE; INFRAME MUTATION; KNOCKOUT GENE; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; MISSENSE MUTATION; MLL GENE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PTEN GENE; RB1 GENE; SLIT2 GENE; SOMATIC MUTATION; SPLICING DEFECT; TUMOR SUPPRESSOR GENE;

AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE, TUMOR; CREB-BINDING PROTEIN; DNA COPY NUMBER VARIATIONS; DNA MUTATIONAL ANALYSIS; E1A-ASSOCIATED P300 PROTEIN; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG NEOPLASMS; MICE; MICE, KNOCKOUT; MODELS, MOLECULAR; MUTATION; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NERVE TISSUE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PTEN PHOSPHOHYDROLASE; RETINOBLASTOMA PROTEIN; SMALL CELL LUNG CARCINOMA; TUMOR SUPPRESSOR PROTEIN P53;

MUS;

EID: 84866851740     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2396     Document Type: Article

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